|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Fhe roles and functional mechanisms of interleukin-17 amily cytokines in mucosal immunity显示文摘 | Xinyang Song Xiao He Xiaoxia Li Youcun Qian | 2016 | Cellular & Molecular Immunology2016，13，4： | 29 |
| 2 | NLRC5 regulates MHC class I antigen presentation in host defense against intracellular pathogens显示文摘像点头的受体(NLR ) 是对微生物引起的感染在天生的免疫起关键作用的细胞内部的蛋白质的一个家庭。NLRC5, NLR 家庭的最大的成员,最近吸引了许多注意。然而,在 vitro,研究在主人防卫并且在调整有免疫力的发信号的小径关于 NLRC5 的角色报导了不一致的结果。在里面 NLRC5 的 vivo 功能仍然保持未知。这里,我们报导 NLRC5 是对在 vivo 的细胞内部的病原体的主人防卫的一个批评管理者。NLRC5 明确地为涉及 MHC 一级抗原表示的基因的表示被要求。NLRC5 缺乏的老鼠显示了在 MHC 一级基因和伴随物失败的表示的一个深刻缺点激活 L。monocytogenes 特定的 CD8 + T 房间回答,包括的激活,增长和 cytotoxicity,和变异的老鼠更产生病原体感染。调停 NLRP3 的 inflammasome 激活部分也在 NLRC5 缺乏的老鼠被损害。然而, NLRC5 为 NF-κ 的导致病原体的表示是非必需的; B 依赖的支持 inflammatory 基因以及类型我干扰素基因。因此, NLRC5 极其调整 MHC 一级抗原表示控制细胞内部的病原体感染。 | Yikun Yao Yalong Wang Fuxiang Chen Yin Huang Shu Zhu Qibin Leng Hongyan Wang Yufang Shi Youcun Qian | 2012 | Cell Research2012，22，5： | 13 |
| 3 | Current Status and Future Challenges of Weather Radar Polarimetry: Bridging the Gap between Radar Meteorology/Hydrology/Engineering and Numerical Weather Prediction显示文摘After decades of research and development, the WSR-88 D(NEXRAD) network in the United States was upgraded with dual-polarization capability, providing polarimetric radar data(PRD) that have the potential to improve weather observations,quantification, forecasting, and warnings. The weather radar networks in China and other countries are also being upgraded with dual-polarization capability. Now, with radar polarimetry technology having matured, and PRD available both nationally and globally, it is important to understand the current status and future challenges and opportunities. The potential impact of PRD has been limited by their oftentimes subjective and empirical use. More importantly, the community has not begun to regularly derive from PRD the state parameters, such as water mixing ratios and number concentrations, used in numerical weather prediction(NWP) models.In this review, we summarize the current status of weather radar polarimetry, discuss the issues and limitations of PRD usage, and explore potential approaches to more efficiently use PRD for quantitative precipitation estimation and forecasting based on statistical retrieval with physical constraints where prior information is used and observation error is included. This approach aligns the observation-based retrievals favored by the radar meteorology community with the model-based analysis of the NWP community. We also examine the challenges and opportunities of polarimetric phased array radar research and development for future weather observation. | Guifu ZHANG Vivek N.MAHALE Bryan J.PUTNAM Youcun QI Qing CAO ANDrew D.BYRD Petar BUKOVCIC Dusan S.ZRNIC Jidong GAO Ming XUE Youngsun JUNG Heather D.REEVES Pamela L.HEINSELMAN AlexANDer RYZHKOV Robert D.PALMER Pengfei ZHANG Mark WEBER Greg M.MCFARQUHAR Berrien MOORE III Yan ZHANG Jian ZHANG J.VIVEKANANDAN Yasser AL-RASHID Richard L.ICE Daniel S.BERKOWITZ Chong-chi TONG Caleb FULTON Richard J.DOVIAK | 2019 | Advances in Atmospheric Sciences2019，36，6： | 9 |
| 4 | IL-17 signaling in host defense and inflammatory diseases显示文摘Interleukin(IL)-17,the signature cytokine secreted by T helper(Th)17 cells,plays important roles in host defense against extracellular bacterial infection and fungal infection and contributes to the pathogenesis of various autoimmune inflammatory diseases.Here we review the recent advances in IL-17-mediated functions with emphasis on the studies of IL-17-mediated signal transduction,providing perspective on potential drug targets for the treatment of autoimmune inflammatory diseases. | Youcun Qian Zizhen Kang Caini Liu Xiaoxia Li | 2010 | Cellular & Molecular Immunology2010，7，5： | 7 |
| 5 | Expression regulation and function of NLRC5显示文摘The NOD like receptors(NLRs),a class of intracellular receptors that respond to pathogen attack or cellular stress,have gained increasing attention.NLRC5,the largest member of the NLR protein family,has recently been identified as a critical regulator of immune responses.While NLRC5 is constitutively and widely expressed,it can be dramatically induced by interferons during pathogen infections.Both in vitro and in vivo studies have demonstrated that NLRC5 is a specifi c and master regulator of major mistocompatibility complex(MHC)class I genes as well as related genes involved in MHC class I antigen presentation.The expression of MHC class I genes is regulated by NLRC5 in coordination with the RFX components through an enhanceosome-dependent manner.And the involvement of NLRC5 in MHC class I mediated CD8^(+)T cell activation,proliferation and cytotoxicity is proved to be critical for host defense against intracellular bacterial infections.Nevertheless,the role of NLRC5 in innate immunity remains to be further explored.Here,we review the research advances on the structure,expression regulation and function of NLRC5. | Yikun Yao Youcun Qian | 2013 | Protein & Cell2013，4，3： | 5 |
| 6 | Acute carbon monoxide poisoning in Shandong, China: an observational study显示文摘Background: Carbon monoxide (CO) poisoning remains a major cause of accidental injuries and multiple studies have indicated that CO is also associated with significantly severe or long-term toxicity to the central nervous system. Given that CO poisoning causes serious morbidity and mortality, a better understanding of epidemiological features and clinical characteristics of acute CO poisoning in China is crucial.Methods: We collected the clinical data of acute CO poisoning in patients between November 2019 and April 2020 across Shandong province, China and analyzed its characteristics focusing on the weekly amount and the severity of the confirmed cases.Results: A total number of 21,088 acute CO poisoning cases were diagnosed. The overall incidence of acute CO poisoning was approximately 0.021%. On severity rankings, 63% of confirmed cases (n=13,378) were mild, 27%(n=5635) were moderate, and 10% (n=2075) were severe. Interestingly, the coastal cities had more confirmed cases than the inland/suburban areas in Shandong. Meanwhile, the number of confirmed cases was negatively correlated with the local mean daily temperature (P=0.0167).Conclusions: Mild acute CO poisoning cases accounted for the majority of all confirmed cases during the winter of 2019. In Shandong province, which is located in east China, residents of the coastal cities are more susceptible to CO poisoning than residents of inland cities. | Lina Zhang Di Wu Mingyue Xu Yonghui Bian Youcun Wang Guangkai Gao Qing Sun | 2022 | Chinese Medical Journal2022，，13： | 4 |
| 7 | A small biomoleculeassisted synthesis of iron sulfide nanostructures and magnetic properties 显示文摘 | MIN Yulin CHEN Youcun ZHAO Yingguo | 2009 | Solid State Sci2009，11，： | 1 |
| 8 | 显示文摘 | Min Yulin Zhang Kan Chen Youcun | 2012 | Ultrasonics Sonochemistry2012，19，4： | 1 |
| 9 | Formation of α-Mn2O3nanorods via a hydrothermal-assisted cleavage-decomposition mechanism显示文摘 | Chen Youcun Zhang Yuanguang Yao Qizhi | 2007 | Solid State Chemistry2007，180，： | 1 |
| 10 | Synthesis of nanostructured ZnO/Bi2WO6 heterojunction for photocatalysis application显示文摘 | Min Yulin Zhang Kan Chen Youcun | 2012 | Sep Purif Technol2012，92，1： | 1 |
| 11 | Statistical and Physical Analysis of the Vertical Structure of Precipitation in the Mountainous West Region of the United States Using 11+ Years of Spaceborne Observations from TRMM Precipitation Radar显示文摘 | Cao Qing Hong Yang Gourley Jonathan J Qi Youcun Zhang Jian Wen Yixin Kirstetter Pierre-Emmanuel | 2013 | Journal of Applied Meteorology and Climatology2013，，2： | 1 |
| 12 | A novel fluorescent array for mercury (II) ion in aqueous solution with functionalized cadmium selenide nanoclusters显示文摘 | Jinlong Chen YingChun Gao ZhiBing Xu GenHua Wu YouCun Chen ChangQing Zhu | 2006 | Analytica Chimica Acta2006，，1： | 1 |
| 13 | Enhanced chemical interaction between TiO 2 and graphene oxide for photocatalytic decolorization of methylene blue显示文摘 | YuLin Min Kan Zhang Wei Zhao FangCai Zheng YouCun Chen YuanGuang Zhang | 2012 | Chemical Engineering Journal2012，，： | 1 |
| 14 | IL-17 family cytokines mediated signaling in the pathogenesis of inflammatory diseases 显示文摘 | Xinyang Song Youcun Qian | 2013 | Cel- lular Signalling2013，，25： | 1 |
| 15 | An efficient precursor method to porous hematite architectures and their photocatalytic properties显示文摘 | YuLin Min FangCai Zheng YingGuo Zhao YouCun Chen | 2011 | Solid State Sciences2011，，5： | 1 |
| 16 | A novel fluorescent array for mercury (II) ion in aqueous solution with functionalized cadmium selenide nanoclusters显示文摘 | Jinlong Chen YingChun Gao ZhiBing Xu GenHua Wu YouCun Chen ChangQing Zhu | 2006 | Analytica Chimica Acta2006，，1： | 1 |
| 17 | Halogen chlorine triggered oxygen vacancy-rich Ni(OH)_(2) with enhanced reaction kinetics for pseudocapacitive energy storage显示文摘Two-dimensional (2D)Ni(OH)_(2) nanosheets can theoretically expose their active sites of 100%.Whereas,their intrinsic easy accumulation and low conductivity lead to weak and unsustainable reaction kinetics.Herein,we propose a novel halogen chlorine-triggered electrochemical etching strategy to controllably manage the reaction kinetics of 2D Ni(OH)_(2) nanosheets(EE/Cl-Ni(OH)_(2)).It is found that halogen chlorine doping can adjust the interlamellar spacing flexibly and promote the lattice oxygen activation to achieve controlled construction of superficial oxygen defects at the adjustable voltage.The optimal EE/Cl-Ni(OH)_(2) electrode exhibits a high rate capability and excellent specific capacity of 206.9 mA h g^(-1) at 1 A g^(-1) in a three-electrode system,which is more than twice as high as the pristine Ni(OH)_(2).Furthermore,EE/Cl-Ni(OH)_(2) cathode and FeOOH@rGO anode are employed for developing an aqueous Ni-Fe battery with an excellent energy density of 83 W h kg^(-1),a high power density of 17051 W kg^(-1),and robust durability over 20,000 cycles.This strategy exploits a fresh channel for the ingenious fabrication of highefficiency and stable nickel-based deficiency materials for energy storage. | Jiangyu Hao Lijin Yan Liang Luo Qiaohui Liu Youcun Bai Yuying Han Yang Zhou Xuefeng Zou Bin Xiang | 2023 | Journal of Energy Chemistry2023，，7： | 0 |
| 18 | Create Rich Oxygen Defects of Unique Tubular Hierarchical Molybdenum Dioxide to Modulate Electron Transfer Rate for Superior High-Energy Metal-Ion Hybrid Capacitor显示文摘Metal-ion capacitors could merit advantages from both batteries and capacitors,but they need to overcome the severe restrictions from their sluggish reaction kinetics of the battery type electrode and low specific capacitance of capacitor type electrode for both high energy and power density.Herein,we use the Kirkendall effect for the first time to synthesize unique tubular hierarchical molybdenum dioxide with encapsulated nitrogen-doped carbon sheets while in situ realizing phosphorus-doping to create rich oxygen vacancies(P-MoO_(2-x)@NP-C)as a sodium-ion electrode.Experimental and theoretical analysis confirm that the P-doping introduced oxygen defects can partially convert the high-bond-energy Mo–O to low-bond-energy Mo–P,resulting in a low oxidation state of molybdenum for enhanced surface reactivity and rapid reaction kinetics.The as-prepared P-MoO_(2-x)@NP-C as an ion-battery electrode is further used to pair active N-doped carbon nanosheet(N-C-A)electrode for Na-ion hybrid capacitor,delivering excellent performance with an energy density of 140.3 Wh kg^(−1),a power density of 188.5 W kg^(−1)and long stable life in non-aqueous solution,which ranks the best among all reported MoO x-based hybrid capacitors.P-MoO_(2-x)@NP-C is also used to fabricate a zinc-ion hybrid capacitor,also accomplishing a remarkable energy density of 43.8 Wh kg^(−1),a power density of 93.9 W kg^(−1),and a long stable life@2A g^(−1)of 32000 cycles in aqueous solutions,solidly verifying its universal significance.This work not only demonstrates an innovative approach to synthesize high-performance metal ion hybrid capacitor materials but also reveals certain scientific insights into electron transfer enhancement mechanisms. | Heng Zhang Jinggao Wu Zhuo Zou Youcun Bai Chao Wu Qingxin Zeng Feng Liu Wei Shen Jian Jiang Chang Ming Li | 2023 | Energy & Environmental Materials2023，6，3： | 0 |
| 19 | Natural killer cells go inside: Entosis versus cannibalism显示文摘 | Youcun Qian Yufang Shi | 2009 | Cell Research2009，19，12： | 0 |
| 20 | Calibration of GRACE on-board accelerometers for thermosphere density derivation显示文摘Low Earth Orbit satellite on-board accelerometers play an important role in improving our understanding of thermosphere density;however,the accelerometer-derived densities are subject to accelerometer calibration errors.In this study,two different dynamic calibration schemes,the accelerometer parameter-incorporated orbit fitting and precise orbit determination(POD),are investigated with the Gravity Recovery And Climate Experiment(GRACE)satellite accelerometers for thermosphere density derivation during years 2004–2007(inclusive).We show that the GRACE accelerometer parametrization can be optimized by fixing scale coefficients and estimating biases every 60 min so that the orbit fitting and POD precision can be improved from 10 cm to 2 cm in the absence of empirical acceleration compensations and as a result the integrity of calibration parameters may be reserved.The orbit-fitting scheme demonstrates similar calibration precision with respect to POD.Their bias estimates in the along-track and cross-track components exhibit an offset within 0.1%and a standard deviation(STD)less than 0.3%.Correspondingly,a bias of 2.20%and a STD of 5.75%exists between their thermosphere density estimates.The orbit-fitting and POD-derived thermosphere densities are validated through the comparison against the results published by other institution.The comparison shows that either of them can achieve a precision level at 6%.To derive thermosphere density from the rapid-increasing amount of on-board accelerometer data sets,it is suggested to take full advantage of the orbit-fitting scheme due to its high efficiency as well as high precision. | Min Li Zhuo Lei Wenwen Li Kecai Jiang Youcun Wang Qile Zhao | 2022 | Geo-Spatial Information Science2022，25，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员