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21篇 您的检索式:作者名="Yumeng HAN"
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1Visible-light stimulated synaptic plasticity in amorphous indium−gallium−zinc oxide enabled by monocrystalline double perovskite for high-performance neuromorphic applications显示文摘Photoelectric synaptic devices have been considered as one of the key components in artificial neuromorphic systems due to their excellent capability to emulate the functions of visual neurons,such as light perception and image processing.Herein,we demonstrate an optically-stimulated artificial synapse with a clear photoresponse from ultraviolet to visible light,which is established on a novel heterostructure consisting of monocrystalline Cs2AgBiBr6 perovskite and indium–gallium–zinc oxide(IGZO)thin film.As compared with pure IGZO,the heterostructure significantly enhances the photoresponse and corresponding synaptic plasticity of the devices,which originate from the superior visible absorption of single-crystal Cs2AgBiBr6 and effective interfacial charge transfer from Cs2AgBiBr6 to IGZO.A variety of synaptic behaviors are realized on the fabricated thin-film transistors,including excitatory postsynaptic current,paired pulse facilitation,short-term,and long-term plasticity.Furthermore,an artificial neural network is simulated based on the photonic potentiation and electrical depression effects of synaptic devices,and an accuracy rate up to 83.8%±1.2%for pattern recognition is achieved.This finding promises a simple and efficient way to construct photoelectric synaptic devices with tunable spectrum for future neuromorphic applications.Fu Huang Feier Fang Yue Zheng Qi You Henan Li Shaofan Fang Xiangna Cong Ke Jiang Ye Wang Cheng Han Wei Chen Yumeng Shi 2023Nano Research2023,16,1:2
2Herbal medicine in the treatment of COVID-19 based on the gut-lung axis显示文摘Respiratory symptoms are most commonly experienced by patients in the early stages of novel coronavirus disease 2019 (COVID-19). However, with a better understanding of COVID-19, gastrointestinal symptoms such as diarrhea, nausea, and vomiting haveattracted increasing attention. The gastrointestinal tract may be a target organ of severe acute respiratory syndrome coronavirus2 (SARS-CoV-2) infection. The intestinal microecological balance is a crucial factor for homeostasis, including immunity andinflammation, which are closely related to COVID-19. Herbal medicine can restore intestinal function and regulate the gut florastructure. Herbal medicine has a long history of treating lung diseases from the perspective of the intestine, which is called thegut-lung axis. The physiological activities of guts and lungs influence each other through intestinal flora, microflora metabolites,and mucosal immunity. Microecological modulators are included in the diagnosis and treatment protocols for COVID-19. Inthis review, we demonstrate the relationship between COVID-19 and the gut, gut-lung axis, and the role of herbal medicine intreating respiratory diseases originating from the intestinal tract. It is expected that the significance of herbal medicine in treatingrespiratory diseases from the perspective of the intestinal tract could lead to new ideas and methods for treatment.Qiaoyu He Yumeng Shi Qian Tang Hong Xing Han Zhang Mei Wang Xiaopeng Chen 2022Acupuncture and Herbal Medicine2022,2,3:1
3Polarization-sensitive and active controllable electromagnetically induced transparency in U-shaped terahertz metamaterials显示文摘Electromagnetically induced transparency(EIT)phenomenon is observed in simple metamaterial which consists of concentric double U-shaped resonators(USRs).The numerical and theoretical analysis reveals that EIT arises from the bright-bright mode coupling.The transmission spectra at different polarization angle of incident light shows that EIT transparency window is polarization sensitive.More interestingly,Fano resonance appears in the transmission spectrum at certain polarization angles.The sharp and asymmetric Fano lineshape is high valuable for sensing.The performance of sensor is investigated and the sensitivity is high up to 327 GHz/RIU.Furthermore,active control of EIT window is realized by incorporating photosensitive silicon.The proposed USR structure is simple and compact,which may find significant applications in tunable integrated devices such as biosensor,filters,and THz modulators.Kun REN Ying ZHANG Xiaobin REN Yumeng HE Qun HAN 2021Frontiers of Optoelectronics2021,14,2:1
4Covalent stabilization of DNA nanostructures on cell membranes for efficient surface receptor-mediated labeling and function regulations显示文摘One major challenge of using DNA nanostructures for cellular and in vivo applications is their insufficiently structural integrity that stems from the non-covalent base pairing and stacking in complex cellular and physiological environment. The establishment of covalent bonds in DNA nanostructures can link individual strands more stably and therefore should improve the performance of DNA nanostructures in different scenarios where structural integrity is required. Here, we developed a convenient and effective method for constructing covalently stabilized DNA nanostructures by chemically inserting photo-crosslinker(^(CNV)K) in DNA sequences. These covalently linked DNA nanostructures were found to be more resistant to external interference, such as low cation concentrations and unspecific displacement on cell membranes. We also demonstrated that our strategy could improve the efficiency of cell surface receptor-mediated labeling and function regulations in living cells, which sheds light on broadening the biomedical applications of DNA nanostructures.Dandan Chao Xuemei Xu Yanyan Miao Linlin Yang Qianqian Gao Rui Xu Yuan Tian Yumeng Zhao Yuzhen Du Da Han 2022Science China Chemistry2022,65,11:0
5Impact of Cold Spells on Ischemic Stroke Severity and Clinical Outcomes in Tianjin, China显示文摘There are several studies on the impact of extreme weather on the incidence and mortality of stroke, but the research on the effect of extreme weather events on severity and outcome of ischemic stroke is scarce. This study aimed to evaluate the impact of cold spells on the severity and clinical outcomes of patients with initial acute ischemic stroke in a hospital-based study. We enrolled 553 patients with initial ischemic stroke during the cold seasons between 2016 and 2019. Patients were separated into the mild stroke group and moderate-to-severe stroke group according to the National Institutes of Health Stroke Scale(NIHSS) of the U.S., and good outcome group and poor outcome group according to modified Rankin Scale(mRS) scores. There are nine different definitions of cold spells according to intensities and duration time. After adjustment for climate factors, air quality index, and common risk factors, it is found that cold spells were associated with moderate-to-severe neurological deficits and clinical outcomes in overall ischemic stroke patients. Furthermore, the delay effect for stroke severity started at the beginning of the cold wave(Lag 0) and lasted up to 14 days(Lags 0–14). In addition, when a cold spell was set as a daily mean temperature < 3rd or 5th percentile and with a duration ≥ 2 or 3 consecutive days, cold spells had a significant impact on clinical outcomes, and there was a definite delay effect of at least 7 days(Lags 0–7) and it lasted up to 14days(Lags 0–14). At last, we concluded that cold spells may be a contributory factor for more severe neurological deficits and worse outcomes in patients with initial ischemic stroke.Juanjuan XUE Chanjuan WEI Xiaoshuang XIA Xuemei QI Yumeng GU Zhongyan WANG Suqin HAN Lin WANG Xin LI 2023Journal of Meteorological Research2023,37,4:0
6Tempospacial energy-saving effect-based diagnosis in large coal-fired power units:Energy-saving benchmark state显示文摘The energy-saving analytics of coal-fired power units in China is confronting new challenges especially with even more complicated system structure, higher working medium parameters, time-dependent varying operation conditions and boundaries such as load rate, coal quality, ambient temperature and humidity. Compared with the traditional optimization of specific operating parameters, the idea of the energy-consumption benchmark state was proposed. The equivalent specific fuel consumption(ESFC) analytics was introduced to determine the energy-consumption benchmark state, with the minimum ESFC under varying operation boundaries. Models for the energy-consumption benchmark state were established, and the endogenous additional specific consumption(ASFC) and exogenous ASFC were calculated. By comparing the benchmark state with the actual state, the energy-saving tempospacial effect can be quantified. As a case study, the energy consumption model of a 1000 MW ultra supercritical power unit was built. The results show that system energy consumption can be mainly reduced by improving the performance of turbine subsystem. This nearly doubles the resultant by improving the boiler system. The energy saving effect of each component increases with the decrease of load and has a greater influence under a lower load rate. The heat and mass transfer process takes priority in energy saving diagnosis of related components and processes. This makes great reference for the design and operation optimization of coal-fired power units.FU Peng WANG NingLing YANG Yong Ping XU Han LI XiaoEn ZHANG YuMeng 2015Science China(Technological Sciences)2015,58,12:0
7Overview of Recombinant Skin Models and Progress in Their Application in Vitro Assessment of Toxicity and Efficacy显示文摘A recombinant skin model is a model in which skin cells are grown in vitro on a bioactive scaffold and provided with adequate nutrition to promote cell proliferation and differentiation to produce a mock skin structure and biological features. The development of recombinant skin models allows for effective and scientifically sound in vitro evaluation tests. This review briefly summarizes the overview of recombinant skin models and the progress of their application in in vitro evaluation which focuses on three aspects: skin irritation, skin corrosivity, and anti-skin aging. Moreover, an outlook on the future development of recombinant skin models is also provided in this review.Zhang Bowen Xu Qiufeng GU Wu Zhang Zhichun Dai Yumeng Han Zhiyang Xu Mingkai Wang Yu 2023China Detergent & Cosmetics2023,8,1:0
8LIANGHEKOU:Regeneration of an Ancient Tujia Village along the Salt Road显示文摘Profile:In the upcoming tourism development,Lianghekou Village will resume its commercial function during the period of Salt Road trading and become a gathering place for locals and tourists.Timber Loggia and Silankarp Workshop in Lianghe-kou village show that the self-adaptaility of traditional Tujia wooden construction techniques can be transmitted to meet modern needs in contemporary architectural design.This project was exhibited and themed'Lianghekou:A Tujia Vllage of Re-Living-Together'on the 17th International Architecture Exhibition-La Biennale di Venezia in 2021.ZHANG Tong XU Han WANG Chuan MA Yumeng SUI Mingming CHEN Siyu YANG Chen RENG Ziqiu ZOU Yue LIN Siyuan 2022Frontiers of Architectural Research2022,11,5:0
9Electrochemical properties of LaFeO3-rGO composite显示文摘LaFeO_3-xwt% r GO composite(x = 8, 10, 12) was synthesized by ultraphonic stirring and lyophilization method.SEM, TEM and XRD results show that the perovskite-type LaFeO_3 was dispersed by rGO to form special porous structure due to the gauze-shaped wrinkles and folds structure of rGO. It was found that the special porous structure can effectively increase the specific surface area and suppress particle aggregation of LaFeO_3, thus improving the electrical conductivity and appreciably enhancing the electrochemical properties of LaFeO_3. As compared with LaFeO_3, the maximum discharge capacity of the composite(x=10) increased from 209.5 mAhg^(–1) to 334.6 mAhg^(–1).The High rate dischargeability at a discharge current density of 1500 mAg^(–1)(HRD1500) and the capacity retention rate after 100 charge/discharge cycles(S100) of the composite increased by 9% and 17%, respectively.Yongjie Yuan Zhentao Dong Yuan Li Lu Zhang Yumeng Zhao Bo Wang Shumin Han 2017Progress in Natural Science:Materials International2017,27,1:0
10Interlayer exciton dynamics of transition metal dichalcogenide heterostructures under electric fields显示文摘Stacking single layers of atoms on top of each other provides a fundamental way to achieve novel material systems and engineer their physical properties,which offers opportunities for exploring fundamental physics and realizing next-generation optoelectronic devices.Among the two-dimensional(2D)-stacked systems,transition metal dichalcogenide(TMDC)heterostructures are particularly attractive because they host tightly-bonded interlayer excitons which possess various novel and appealing properties.These interlayer excitons have drawn significant research attention and hold high potential for the application in unique optoelectronic devices,such as polarization-and wavelength-tunable single photon emitters,valley Hall transistors,and possible high-temperature superconductors.The development of these devices requires a comprehensive understanding of the fundamental properties of these interlayer excitons and the impact of electric fields on their behaviors.In this review,we summarize the recent advances on the understanding of interlayer exciton dynamics under electric fields in TMDC heterostructures.We put emphasis on the electrical modulation of interlayer excitons’emission,the valley Hall transport of charge carriers after the separation of interlayer excitons by an electric field,and the correlation physics of interlayer excitons and charges under electrical doping and tuning.Challenges and perspectives are finally discussed for the application of TMDC heterostructures in future optoelectronics.Jian Tang Yue Zheng Ke Jiang Qi You Zhentian Yin Zihao Xie Henan Li Cheng Han Xiaoxian Zhang Yumeng Shi 2024Nano Research2024,17,5:0
11Molecular Simulation on Aggregation of the Oxidation Products and Dispersion Mechanism of Gasoline Detergent显示文摘By using molecular dynamics simulations based on the classical mechanic method,the dispersion behavior of gasoline detergent in deposit aggregation system was investigated.The representative simulation relating to the deposit molecules and the gasoline detergent molecules with high market share were selected as the model compounds.The microscopic mechanism of dispersing function of gasoline detergent was revealed in detail.It was found that due to Einterac(depo-depo)>Einteraction(gaso-gaso)>Einteraction(gaso-depo),the deposits were driven to gradually aggregate themselves in the gasoline medium.The relative strong interaction between characteristic groups in detergent molecules and deposits could weaken the interaction between deposit aggregates,which mainly comes from the Van der Waals force,the electrostatic interaction,and the orbital interaction.In order to play the dispersing role of detergent,the main factor is to enhance the interaction between the gasoline detergent and the deposit appropriately from the viewpoint of molecular structure design.Li Na Long Jun Zhao Yi Tao Zhiping Guo Xin Han Lu Chen Yumeng 2020China Petroleum Processing & Petrochemical Technology2020,22,1:0
12An ethylene-induced NAC transcription factor acts as a multiple abiotic stress responsor in conifer显示文摘The proper response to various abiotic stresses is essential for plants’survival to overcome their sessile nature,especially for perennial trees with very long-life cycles.However,in conifers,the molecular mechanisms that coordinate multiple abiotic stress responses remain elusive.Here,the transcriptome response to various abiotic stresses like salt,cold,drought,heat shock and osmotic were systematically detected in Pinus tabuliformis(P.tabuliformis)seedlings.We found that four transcription factors were commonly induced by all tested stress treatments,while PtNAC3 and PtZFP30 were highly up-regulated and co-expressed.Unexpectedly,the exogenous hormone treatment assays and the content of the endogenous hormone indicates that the upregulation of PtNAC3 and PtZFP30 are mediated by ethylene.Time-course assay showed that the treatment by ethylene immediate precursor,1-aminocyclopropane-1-carboxylic acid(ACC),activated the expression of PtNAC3 and PtZFP30 within 8 hours.We further confirm that the PtNAC3 can directly bind to the PtZFP30 promoter region and form a cascade.Overexpression of PtNAC3 enhanced unified abiotic stress tolerance without growth penalty in transgenic Arabidopsis and promoted reproductive success under abiotic stress by shortening the lifespan,suggesting it has great potential as a biological tool applied to plant breeding for abiotic stress tolerance.This study provides novel insights into the hub nodes of the abiotic stresses response network as well as the environmental adaptation mechanism in conifers,and provides a potential biofortification tool to enhance plant unified abiotic stress tolerance.Fangxu Han Peiyi Wang Xi Chen Huanhuan Zhao Qianya Zhu Yitong Song Yumeng Nie Yue Li Meina Guo Shihui Niu 2023Horticulture Research2023,10,8:0
13An Initial Perturbation Method for the Multiscale Singular Vector in Global Ensemble Prediction显示文摘Ensemble prediction is widely used to represent the uncertainty of single deterministic Numerical Weather Prediction(NWP) caused by errors in initial conditions(ICs). The traditional Singular Vector(SV) initial perturbation method tends only to capture synoptic scale initial uncertainty rather than mesoscale uncertainty in global ensemble prediction. To address this issue, a multiscale SV initial perturbation method based on the China Meteorological Administration Global Ensemble Prediction System(CMA-GEPS) is proposed to quantify multiscale initial uncertainty. The multiscale SV initial perturbation approach entails calculating multiscale SVs at different resolutions with multiple linearized physical processes to capture fast-growing perturbations from mesoscale to synoptic scale in target areas and combining these SVs by using a Gaussian sampling method with amplitude coefficients to generate initial perturbations. Following that, the energy norm,energy spectrum, and structure of multiscale SVs and their impact on GEPS are analyzed based on a batch experiment in different seasons. The results show that the multiscale SV initial perturbations can possess more energy and capture more mesoscale uncertainties than the traditional single-SV method. Meanwhile, multiscale SV initial perturbations can reflect the strongest dynamical instability in target areas. Their performances in global ensemble prediction when compared to single-scale SVs are shown to(i) improve the relationship between the ensemble spread and the root-mean-square error and(ii) provide a better probability forecast skill for atmospheric circulation during the late forecast period and for short-to medium-range precipitation. This study provides scientific evidence and application foundations for the design and development of a multiscale SV initial perturbation method for the GEPS.Xin LIU Jing CHEN Yongzhu LIU Zhenhua HUO Zhizhen XU Fajing CHEN Jing WANG Yanan MA Yumeng HAN 2024Advances in Atmospheric Sciences2024,41,3:0
14Trimetaphosphate-induced chiral selection between amino acid and nucleoside using ^(15)N-^(31)P coupling NMR显示文摘Life on Earth uses a common set of L-amino acids(L-aa)to construct proteins and D-nucleosides(D-Nu)to form nucleic acids,which serve as the carrier of genetic information.Herein,we reveal the in-trinsic mechanism of chiral selection of L-aa and D-Nu from the perspective of chemical origin of life.This work employed^(15)N-labeled L-aa and performed one-pot synthesis of nucleotide amidate of amino acid(N-aa-NMP)using equal amounts of L-^(15)N-aa and D-^(14)N-aa with D-/L-Nu in the aqueous solution of trimetaphosphate,generating L-^(15)N-aa-NMP and D-^(14)N-aa-NMP,respectively.The ^(31)P-NMR data indicated that L-aa was preferentially selected during the formation of N-aa-NMP in the presence of D-Nu.Surpris-ingly,D-aa was preferred over L-aa in the presence of L-Nu.Further analysis revealed that L-^(15)N-aa-D-NMP vs.D-^(14)N-aa-L-NMP and D-^(14)N-aa-D-NMP vs.L-^(15)N-aa-L-NMP were mirror isomers of each other,respec-tively.These data suggest that there could be a set of chiral systems opposite to that on Earth,which infers there might be a world of life that is a mirror image of the Earth.Jianxi Ying Ruiwen Ding Yumeng Zhang Bowen Han Yeting Guo Ning Wang Dandan Guo Yile Wu Junwei Huang Yan Liu Feng Ni Shaohua Huang Yufen Zhao 2022Chinese Chemical Letters2022,33,2:0
15Efficiently band-tailored type-Ⅲ van der Waals heterostructure for tunnel diodes and optoelectronic devices显示文摘Broken-gap(type-Ⅲ)two-dimensional(2D)van der Waals heterostructures(vdWHs)offer an ideal platform for interband tunneling devices due to their broken-gap band offset and sharp band edge.Here,we demonstrate an efficient control of energy band alignment in a typical type-ⅢvdWH,which is composed of vertically-stacked molybdenum telluride(MoTe2)and tin diselenide(SnSe2),via both electrostatic and optical modulation.By a single electrostatic gating with hexagonal boron nitride(hBN)as the dielectric,a variety of electrical transport characteristics including forward rectifying,Zener tunneling,and backward rectifying are realized on the same heterojunction at low gate voltages of±1 V.In particular,the heterostructure can function as an Esaki tunnel diode with a room-temperature negative differential resistance.This great tunability originates from the atomicallyflat and inert surface of h-BN that significantly suppresses the interfacial trap scattering and strain effects.Upon the illumination of an 885 nm laser,the band alignment of heterojunction can be further tuned to facilitate the direct tunneling of photogenerated charge carriers,which leads to a high photocurrent on/off ratio of>105 and a competitive photodetectivity of 1.03×1012 Jones at zero bias.Moreover,the open-circuit voltage of irradiated heterojunction can be switched from positive to negative at opposite gate voltages,revealing a transition from accumulation mode to depletion mode.Our findings not only promise a simple strategy to tailor the bands of type-ⅢvdWHs but also provide an in-depth understanding of interlayer tunneling for future low-power electronic and optoelectronic applications.Xiangna Cong Yue Zheng Fu Huang Qi You Jian Tang Feier Fang Ke Jiang Cheng Han Yumeng Shi 2022Nano Research2022,15,9:0
16The long road to bloom in conifers显示文摘More than 600 species of conifers(phylum Pinophyta)serve as the backbone of the Earth’s terrestrial plant community and play key roles in global carbon and water cycles.Although coniferous forests account for a large fraction of global wood production,their productivity relies largely on the use of genetically improved seeds.However,acquisition of such seeds requires recurrent selection and testing of genetically superior parent trees,eventually followed by the establishment of a seed orchard to produce the improved seeds.The breeding cycle for obtaining the next generation of genetically improved seeds can be significantly lengthened when a target species has a long juvenile period.Therefore,development of methods for diminishing the juvenile phase is a cost-effective strategy for shortening breeding cycle in conifers.The molecular regulatory programs associated with the reproductive transition and annual reproductive cycle of conifers are modulated by environmental cues and endogenous developmental signals.Mounting evidence indicates that an increase in global average temperature seriously threatens plant productivity,but how conifers respond to the ever-changing natural environment has yet to be fully characterized.With the breakthrough of assembling and annotating the giant genome of conifers,identification of key components in the regulatory cascades that control the vegetative to reproductive transition is imminent.However,comparison of the signaling pathways that control the reproductive transition in conifers and the floral transition in Arabidopsis has revealed many differences.Therefore,a more complete understanding of the underlying regulatory mechanisms that control the conifer reproductive transition is of paramount importance.Here,we review our current understanding of the molecular basis for reproductive regulation,highlight recent discoveries,and review new approaches for molecular research on conifers.Jingjing Ma Xi Chen Fangxu Han Yitong Song Biao Zhou Yumeng Nie Yue Li Shihui Niu 2022Forestry Research2022,2,1:0
17Micropore engineering on hollow nanospheres for ultra-stable sodium-selenium batteries显示文摘Attracted by high energy density and considerable conductivity of selenium(Se),Na-Se batteries have been deemed promising energy-storage systems.But,it still suffers from sluggish kinetic behaviors and similar“shuttling effect”to S-electrodes.Herein,utilizing uniform hollow carbon spheres as precursors,Se-material is effectively loaded through vapor-infiltration method.Owing to the distribution of optimized pores,the content of microspores could be up to~60%(<2 nm),serving important roles for the physical confinement effect.Meanwhile,the rich oxygen-containing groups and N-elements could be noted,inducing the evolution of electron-moving behaviors.More significantly,assisted by the interfacial C-Se bonds and tiny Se distributions,Se electrodes are activated during cycling.Used as cathodes for Na-Se systems,the as-resulted samples display a capacity of 593.9 mA h g^(-1)after 100 cycles at the current density of 0.1 C.Even after 6000 cycles,the capacity could be still kept at about 225 mA h g^(-1)at 5.0 C.Supported by the detailed kinetic analysis,the designed microspores size induces the increasing redox reaction of nano Se,whilst the surface traits further render the enhancement of pseudo-capacitive contributions.Moreover,after cycling,the product Sex(x<4)in pores serves as the primary active material.Given this,the work is anticipated to provide an effective strategy for advanced electrodes for Na-Se systems.Gongke Wang Yumeng Chen Yu Han Lixue Yang Wenqing Zhao Changrui Chen Zihao Zeng Shuya Lei Shaohui Yuan Peng Ge 2023Journal of Energy Chemistry2023,,5:0
18Optimizing 2D-metal contact in layered Tin-selenide via native oxide modulation显示文摘The discovery of two-dimensional(2D)semiconductor has opened up new avenues for the development of short-channel field-effect transistors(FETs)with desired electrical performance.Among them,orthorhombic tin-selenide(SnSe)has garnered increasing attention due to its potential applications in a variety of electronic,optoelectronic,and thermoelectric devices.However,the realization of high-performance SnSe FETs with low contact resistance(Rc)remains a challenge.Herein,we systematically investigate the contact of few-layer SnSe FETs through the modulation of native oxide on SnSe by using different metals.It is found that chromium(Cr)-contacted devices possess the best FET performance,such as electron mobility up to 606 cm^(2)/(V·s)at 78 K,current on/off ratio exceeding 1010,and saturation current of~550μA/μm,where a negligible Schottky barrier(SB)of~30 meV and a low contact resistance of~425Ωμm are achieved.X-ray photoelectron spectroscopy(XPS)and cross-sectional electron dispersive X-ray spectroscopy(EDX)results further reveal that the improved contact arises from the Cr-induced reduction of native oxide(SnOx)to Sn,which thins the tunneling barrier for efficient electron injection.Our findings provide a deep insight into the 2D-metal contact of SnSe and pave the way for its applications in future nanoelectronics.Yue Zheng Qi You Zhentian Yin Jian Tang Ke Jiang Zihao Xie Henan Li Cheng Han Yumeng Shi 2024Nano Research2024,17,4:0
19Determination of conifer age biomarker DAL1 interactome using Y2H-seq显示文摘Age is a sophisticated physiological signal that ensures the sequence of different developmental stages in organisms.The regulation of ageing pathways appears to differ between gymnosperms and angiosperms.We previously identified DAL1 as a conserved conifer age biomarker that plays a crucial role in the transition from vegetative to reproductive life-history phases in pines.Therefore,elucidating the specific interaction events related to DAL1 is key to understanding how age drives conifer development.Large-scale yeast two-hybrid(Y2H)analysis followed by next-generation high-throughput sequencing(Y2H-seq)allowed us to identify 135 PtDAL1 interacting proteins in Pinus tabuliformis.Our study found that PtDAL1 interacting proteins showed an ageing-related module,with sophisticated interacting networks composed of transcription factors(TFs),transcriptional regulators(TRs),and kinases.These interacting proteins are produced in response to a variety of phytohormones and environmental signals,and are likely involved in wood formation,needle development,oleoresin terpenoids biosynthesis,and reproductive development.In this study,we propose a novel regulation model of conifer ageing pathways whereby PtDAL1 coordinates different environmental stimuli and interacts with corresponding proteins to regulate appropriate development.Xi Chen Qianya Zhu Yumeng Nie Fangxu Han Yue Li Harry XWu Shihui Niu 2021Forestry Research2021,1,1:0
20ABE-induced PDGFD start codon silencing unveils new insights into the genetic architecture of sheep fat tails显示文摘Sheep is an important livestock species raised globally to produce meat,milk,wool,and other by-products.During the Neolithic Revolution,sheep were domesticated in the Fertile Crescent of Southwest Asia around 10,000 years ago(Chessa et al.,2009).Peter Kalds Shuhong Huang Shiwei Zhou Siyuan Xi Yumeng Fang Yawei Gao Kexin Sun Chao Li Bei Cai Yao Liu Yige Ding Qifang Kou Tad Sonstegard Bjöm Petersen Stephen Kemp Baohua Ma Jian-Lin Han Yulin Chen Xiaolong Wang 2023Journal of Genetics and Genomics2023,50,12:0
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