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| 1 | Photocatalytic degradation of methyl orange using ZnO/TiO_(2) composites显示文摘ZnO/TiO_(2)composites were synthesized by using the solvothermal method and ultrasonic precipitation followed by heat treatment in order to investigate their photocatalytic degradation of methyl orange(MO)in aqueous suspension under UV irradiation.The composition and surface structure of the catalyst were characterized by X-ray diffraction(XRD),field emission scanning electron microscope(FE-SEM),and transmission electron microscopy(TEM).The degradation efficiencies of MO at various pH values were obtained.The highest degradation efficiencies were obtained before 30 min and after 60 min at pH 11.0 and pH 2.0,respectively.A sample analysis was conducted using liquid chromatography coupled with electrospray ionization ion-trap mass spectrometry.Six intermediates were found during the photocatalytic degradation process of quinonoid MO.The degradation pathway of quinonoid MO was also proposed. | Ming GE Changsheng GUO Xingwang ZHU Lili MA Zhenan HAN Wei HU Yuqiu WANG | 2009 | Frontiers of Environmental Science & Engineering2009，3，3： | 3 |
| 2 | Water-trapping and drag-reduction effects of fish Ctenopharyngodon idellus scales and their simulations显示文摘In the last decades, surface drag reduction has been re-emphasized because of its practical values in engineering applications,including vehicles, aircrafts, ships, and fuel pipelines. The bionic study of drag reduction has been attracting scholars' attentions. Here, it was determined that the delicate microstructures on the scales of the fish Ctenopharyngodon idellus exhibit remarkable drag-reduction effect. In addition, the underlying drag-reduction mechanism was carefully investigated. First,exceptional morphologies and structures of the scales were observed and measured using a scanning electron microscope and3-dimensional(3D) microscope. Then, based on the acquired data, optimized 3D models were created. Next, the mechanism of the water-trapping effect of these structures was analyzed through numerical simulations and theoretical calculations. It was determined that there are many microcrescent units with certain distributions on its surface. In fact, these crescents are effective in generating the 'water-trapping' effect and forming a fluid-lubrication film, thus reducing the skin friction drag effectively.Contrasting to a smooth surface, the dynamics finite-element analysis indicated that the maximum drag-reduction rate of a bionic surface is 3.014% at 0.66 m/s flow rate. This study can be used as a reference for an in-depth analysis on the bionic drag reduction of boats, underwater vehicles, and so forth. | WU LiYan JIAO ZhiBin SONG YuQiu REN WenTao NIU ShiChao HAN ZhiWu | 2017 | Science China(Technological Sciences)2017，60，7： | 3 |
| 3 | Antibiotics-mediated intestinal microbiome perturbation aggravates tacrolimus-induced glucose disorders in mice显示文摘Both immunosuppressants and antibiotics (ABX) are indispensable for transplant patients. However, the former increases the risk of new-onset diabetes, whereas the latter impacts intestinal microbiota (IM). It is still unclear whether and how the interaction between immunosuppressants and ABX alters the IM and thus leads to glucose metabolism disorders. This study examined the alterations of glucose and lipid metabolism and IM in mice exposed to tacrolimus (TAC) with or without ABX. We found that ABX further aggravated TAC-induced glucose tolerance and increased insulin secretion. Combined treatment resulted in exacerbated lipid accumulation in the liver. TAC-altered microbial community was further amplified by ABX administration, as characterized by reductions in phylum Firmicutes, family Lachnospiraceae, and genus Copyococcus. Analyses based on the metagenomic profiles revealed that ABX augmented the effect of TAC on microbial metabolic function mostly related to lipid metabolism. The altered components of gut microbiome and predicted microbial functional profiles showed significant correlation with hepatic lipid accumulation and glucose disorders. In conclusion, ABX aggravated the effect of TAC on the microbiome and its metabolic capacities, which might contribute to hepatic lipid accumulation and glucose disorders. These findings suggest that the ABX-altered microbiome can amplify the diabetogenic effect of TAC and could be a novel therapeutic target for patients. | Yuqiu Han Xiangyang Jiang Qi Ling Li Wu Pin Wu Ruiqi Tang Xiaowei Xu Meifang Yang Lijiang Zhang Weiwei Zhu Baohong Wang Lanjuan Li | 2019 | Frontiers of Medicine2019，13，4： | 3 |
| 4 | Optimization of phosphorus removal from secondary effluent using simplex method in Tianjin,China显示文摘 | Wang Yuqiu Han Tianwei Xu Ze | | 0，，1： | 1 |
| 5 | Optimization of phosphorus removal from secondary effluent using simplex method in Tianjin,China显示文摘 | Tianwei Han Ze Xu | 2005 | Journal of Hazardous Materials2005，121，13： | 1 |
| 6 | Gut Microbiota-Controlled Tryptophan Metabolism Improves D-Gal/LPS-Induced Acute Liver Failure in C57BL/6 Mice显示文摘Acute liver failure(ALF)has an abrupt onset with a frequently fatal outcome.Previous studies have found that oral antibiotics prevent drug-induced liver injury in animal experiments,indicating that the gut microbiota plays a critical role in the pathophysiological process.However,the underlying mechanism has not been fully understood.This study explored the comprehensive role of the gut microbiota in ALF using multi-omics.A cocktail of broad-spectrum antibiotics(Abx)pretreatment by gavage for four weeks improved the survival of D-(+)-galactosamine hydrochloride(D-Gal)/lipopolysaccharide(LPS)-induced ALF in C57BL/6 mice.RNA sequencing showed that inflammatory responses were inhibited and metabolic pathways were upregulated in the liver of Abx-treated ALF mice.The 16S rRNA gene sequencing revealed that Abx reshaped the composition and function of the gut microbiota,with an increased proportion of tryptophan(Trp)metabolism.In addition,global metabolic profiling by ultraperformance liquid chromatography–mass spectrometry(UPLC–MS)indicated that the gut microbiota post-Abx intervention reduced Trp excretion,liberated more Trp to the host,and enhanced the kynurenine(Kyn)pathway with increased production of Kyn.As an endogenous aryl hydrocarbon receptor(AhR)ligand,Kyn has anti-inflammatory and immunosuppressive effects.Furthermore,AhR-targeted treatments affected the outcome of ALF mice with or without Abx pretreatment,indicating that AhR directly regulated susceptibility to ALF,at least in part.This study demonstrates that the gut microbiota-dependent control of the Trp metabolism could regulate host susceptibility to ALF by modulating the activity of AhR,and thus provides a promising target for better management of ALF. | Zhipeng Zheng Li Wu Yuqiu Han Jun Chen Shuai Zhu Yuanyuan Yao Baohong Wang Lanjuan Li | 2022 | Engineering2022，8，7： | 1 |
| 7 | Role of Akkermansia muciniphila in the development of nonalcoholic fatty liver disease: current knowledge and perspectives显示文摘Nonalcoholic fatty liver disease(NAFLD)is a hepatic manifestation of metabolic syndrome and a common cause of liver cirrhosis and cancer.Akkermansia muciniphila(A.muciniphila)is a next-generation probiotic that has been reported to improve metabolic disorders.Emerging evidence indicates the therapeutic potential of A.muciniphila for NAFLD,especially in the inflammatory stage,nonalcoholic steatohepatitis.Here,the current knowledge on the role of A.muciniphila in the progression of NAFLD was summarized.A.muciniphila abundancy is decreased in animals and humans with NAFLD.The recovery of A.muciniphila presented benefits in preventing hepatic fat accumulation and inflammation in NAFLD.The details of how microbes regulate hepatic immunity and lipid accumulation in NAFLD were further discussed.The modulation mechanisms by which A.muciniphila acts to improve hepatic inflammation are mainly attributed to the alleviation of inflammatory cytokines and LPS signals and the downregulation of microbiota-related innate immune cells(such as macrophages).This review provides insights into the roles of A.muciniphila in NAFLD,thereby providing a blueprint to facilitate clinical therapeutic applications. | Yuqiu Han Lanjuan Li Baohong Wang | 2022 | Frontiers of Medicine2022，16，5： | 1 |
| 8 | Replication of Papilio maackii Ménétriés butterfly scale structural color using a magnetron sputtering method显示文摘The natural butterfly Papilio maackii Ménétriés scales were found, through scanning and transmission electron microscopy, to comprise stacks of thin layers. Replicated scales were then fabricated on a silicon substrate using a magnetron sputtering (MS) method with ITO (In2O3(90%)+SnO2(10%)) and polymethyl methacrylate (PMMA). Finally, the optical effects of the replicated scale were examined by a spectrometer. The results showed that the replicated and natural scales have the similar characteristics in structural colors. As a result, it can be concluded that the MS method reported in this paper is a feasible method for fabricating an artificial biological structural color or other optical elements. | WU LiYan HAN ZhiWu SONG YuQiu NIU ShiChao Ren LuQuan | 2012 | Chinese Science Bulletin2012，57，34： | 1 |
| 9 | 肝脏移植术后糖尿病患者肠道微生物组的变化显示文摘Post-transplant diabetes mellitus(PTDM)increases the risk of graft failure and death in liver transplant(LT)recipients.Experimental studies have indicated that enteric dysbiosis mediated by immunosuppressive tacrolimus(TAC)could contribute to glucose disorders,but no data on human recipients with PTDM have been reported.Here,by combining high-throughput shotgun metagenomics sequencing and metabolomics profiling,we characterized the intestinal microbiome(IM)in LT recipient cohort with or without PTDM and deciphered the potential relationship among IM,TAC dosage,and diabetes.By comparing with both non-PTDM and classical type 2 diabetes mellitus(T2DM),we identified microbial signatures of PTDM,which was characterized by the enriched Proteobacteria and decreased Bacteroidetes.Additionally,the altered microbes,as well as the microbial metabolomics,correlated with the dosage of TAC.Specifically,the levels of beneficial microbes associated with PTDM were lowered in recipients with the high TAC trough concentrations(>5 ng·mL^(-1))than those with low ones(<5 ng·mL^(-1)),which was accompanied by reduced faecal metabolites involved in the biosynthesis of a-linolenic acid and arachidonic acid-lowering factors of developing T2DM.Moreover,these microbial signatures linked with the extent of glucose disorders in LT recipients.In summary,the faecal microbiome and metabolome differed between PTDM and non-PTDM patients,which were linked with TAC dosage.This study was the first to explore taxonomic alterations and bacterial gene functions to better understand the contribution of the IM to PTDM. | Qi Ling Yuqiu Han Yue Ma Xiaosen Wang Zheng Zhu Jingyu Wang Jiaying Cao Lin Xiaohan Jun Wang Baohong Wang | 2023 | Engineering2023，31，12： | 0 |
| 10 | The Development of Early Life Microbiota in Human Health and Disease显示文摘The colonization of the human microbiota in early life has long-lasting health implications.The status of the initial intestinal microbiota determines human growth and development from infancy to adulthood,and thus represents a crucial window in our long-term development.This review aims to summarize the latest findings on the symbiotic gut microbiota early in life and its vital role in metabolic-,allergic-,and auto-immune-disorder-related diseases,including obesity,diabetes,allergy,autism,inflammatory bowel disease,and stunting.It discusses the development process and various factors shaping the gut micro-biota,as well as the crosstalk between the gut microbiota and the host’s physiological systems(especially intestinal immune development and homeostasis,and the central nervous system in the course of neu-rodevelopment),during the early life establishment of the gut microbiota,in order to decipher the mech-anisms of diseases associated with the intestinal microbiome of early life.In addition,it examines microbiota-targeted therapeutic methods that show promising effects in treating these diseases.The true process of gut microbiome maturation,which depends on genetics,nutrition,and environmental factors,must be scrutinized in order to monitor healthy gut microbiome development and potentially correct unwanted courses by means of intervention via methods such as novel probiotics or fecal microbiota transplantation. | Hanying Lv Lijiang Zhang Yuqiu Han Li Wu Baohong Wang | 2022 | Engineering2022，8，5： | 0 |
| 11 | Commissioning experiment of the high-contrast SILEX-Ⅱ multi-petawatt laser facility显示文摘The results of a commissioning experiment on the SILEX-Ⅱlaser facility(formerly known as CAEP-PW)are reported.SILEX-Ⅱis a complete optical parametric chirped-pulse amplification laser facility.The peak power reached about 1 PWin a 30 fs pulse duration during the experiment.The laser contrast was better than 1010 at 20 ps ahead of the main pulse.In the basic laser foil target interaction,a set of experimental data were collected,including spatially resolved x-ray emission,the image of the coherent transition radiation,the harmonic spectra in the direction of reflection,the energy spectra and beam profile of accelerated protons,hot-electron spectra,and transmitted laser energy fraction and spatial distribution.The experimental results show that the laser intensity reached 531020 W/cm^(2) within a 5.8μm focus(FWHM).Significant laser transmission did not occur when the thickness of theCHfoil was equal to or greater than 50 nm.The maximum energy of the accelerated protons in the target normal direction was roughly unchanged when the target thickness varied between 50 nm and 15μm.The maximum proton energy via the target normal sheath field acceleration mechanism was about 21 MeV.We expect the on-target laser intensity to reach 10^(22) W/cm^(2) in the near future,after optimization of the laser focus and upgrade of the laser power to 3 PW. | Wei Hong Shukai He Jian Teng Zhigang Deng Zhimeng Zhang Feng Lu Bo Zhang Bin Zhu Zenghai Dai Bo Cui Yuchi Wu Dongxiao Liu Wei Qi Jinlong Jiao Faqiang Zhang Zuhua Yang Feng Zhang Bi Bi Xiaoming Zeng Kainan Zhou Yanlei Zuo Xiaojun Huang Na Xie Yi Guo Jingqin Su Dan Han Ying Mao Leifeng Cao Weimin Zhou Yuqiu Gu Feng Jing Baohan Zhang Hongbo Cai Minqing He Wudi Zheng Shaoping Zhu Wenjun Ma Dahui Wang Yinren Shou Xueqing Yan Bin Qiao Yi Zhang Congling Zhong Xiaohui Yuan and Wenqing Wei | 2021 | Matter and Radiation at Extremes2021，6，6： | 0 |
| 12 | Chemical constituents and biological activities of Azadirachta indica A. Juss显示文摘Azadirachta indica A. Juss is a tropical evergreen plant, belonging to the Meliaceae family. The plant is used as folk medicines for the treatment of fever, neuromuscular pains, skin infections, diabetes and heart disease. Previous researches show that the plant possesses several types of chemical constituents and diverse biological activities. The paper concludes chemical constituents, biological activities and pesticide products of A. indica. | Xuegui Liu Yuqiu Sun Jun Bian Mengchao Lv Ting Han Danqi Li Pinyi Gao | 2019 | Asian Journal of Traditional Medicines2019，14，1： | 0 |
| 13 | Reproductive height determines the loss of clonal grasses with nitrogen enrichment in a temperate grassland显示文摘Tall clonal grasses commonly display competitive advantages with nitrogen(N)enrichment.However,it is currently unknown whether the height is derived from the vegetative or reproductive module.Moreover,it is unclear whether the height of the vegetative or reproductive system regulates the probability of extinction and colonization,and determines species diversity.In this study,the impacts on clonal grasses were studied in a field experiment employing two frequencies(twice a year vs.monthly)crossing with nine N addition rates in a temperate grassland,China.We found that the N addition decreased species frequency and increased extinction probability,but did not change the species colonization probability.A low frequency of N addition decreased species frequency and colonization probability,but increased extinction probability.Moreover,we found that species reproductive height was the best index to predict the extinction probability of clonal grasses in N-enriched conditions.The low frequency of N addition may overestimate the negative effect from N deposition on clonal grass diversity,suggesting that a higher frequency of N addition is more suitable in assessing the ecological effects of N deposition.Overall,this study illustrates that reproductive height was associated with the clonal species extinction probability under N-enriched environment. | Xu Chen Haining Lu Zhengru Ren Yuqiu Zhang Ruoxuan Liu Yunhai Zhang Xingguo Han | 2024 | Plant Diversity2024，46，2： | 0 |
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