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| 1 | Hypoglycemic effect of catalpol on high-fat diet/streptozotocin-induced diabetic mice by increasing skeletal muscle mitochondrial biogenesis显示文摘Catalpol, iridoid glycoside,在根值 Rehmanniae 的根存在。一些研究证明了 catalpol 为这效果在导致 streptozotocin 的糖尿病的模型,而是内在的机制有显著血糖过低的效果充分没被阐明。因为 mitochondrial 机能障碍在糖尿病的病理起一个重要作用并且因为改善 mitochondrial 功能可以为糖尿病的处理提供一条新途径,这研究被设计。Catalpol 口头上地予导致的高脂肪的 diet/streptozotocin (HFD/STZ ) 和 metformin 被以为 4 个星期的糖尿病的老鼠日报。身体重量(BW )(IPGTT ) , fasting 血葡萄糖(FBG ) 水平,和葡萄糖处理被测量在期间或在处理以后。结果整个 catalpol 管理的四个连续星期在 BW 没有明显的变化显示出 FBG 水平的剂量依赖者减小。Catalpol 治疗实质地在糖尿病的老鼠减少了浆液总数胆固醇和 triglyceride 层次。另外, catalpol 高效地增加了 mitochondrial ATP 生产并且在骨胳的肌肉织物颠倒了 mitochondrial 膜潜力和 mtDNA 拷贝数字的减少。而且, catalpol (200 mg/kg ) 在骨胳的肌肉救了 mitochondrial 超微结构,与传播电子显微镜学检测了。peroxisome 的相对 mRNA 水平(PGC1 ) 当这效果被 catalpol 颠倒时,激活 proliferator 的受体 gamma 激活剂 1 显著地在糖尿病的老鼠的肌肉组织被减少,导致一条剂量依赖者起来规定。一起拿,我们发现 catalpol 能够经由在 HFD/STZ-induced 糖尿病的老鼠的骨胳的肌肉改进 mitochondrial 功能的阴沉的 FBG 水平。 | Xia Li Zhimeng Xu Zhenzhou Jiang Lixin Sun Jinzi Ji Jingshan Miao Xueji Zhang Xiaojie Li Shan Huang Tao Wang Luyong Zhang | 2014 | Acta Biochimica et Biophysica Sinica2014,46,9: | 16 |
| 2 | Mitochondrial fusion/fission process involved in the improvement of catalpol on high glucose- induced hepatic mitochondrial dysfunction显示文摘Catalpol, iridoid glycoside,被显示了由 rescuing mitochondrial 功能,而是详细机制遗体施加血糖过低的效果不清楚还。在这研究,在糖尿病的条件下面的肝的线粒体上的 catalpol 的效果和机制进一步被检验。catalpol 的口头的管理显著地在高脂肪的导致食谱、导致 streptozotocin 的糖尿病的老鼠减少了血葡萄糖, triglyceride,和胆固醇层次。另外, catalpol 在源于糖尿病的肝 mitochondrial ATP 内容稀释了减少。而且,拥有一种长尺寸的线粒体的数字在对待 catalpol 的老鼠被增加。有趣地, mitochondrial 功能的导致 catalpol 的恢复与减少的分裂蛋白质 1 被联系并且 dynamin 相关的蛋白质象增加的 mitofusin 一样的 1 个表达式在肝的 1 个表达式。在 HepG2 房间, catalpol 减轻了 ATP 内容和 mitochondrial 膜潜力的减少,并且反应的氧种类形成的增加由高葡萄糖导致了。当房间与 catalpol 被对待时,线粒体的管状的特征被维持的米托特拉克·格林污点表演。Catalpol 也减少了分裂蛋白质 1 并且 dynamin 相关的蛋白质 1 表情和增加的 mitofusin 在 HepG2 房间的 1 表情。现在的结果建议 catalpol 能改善在一名糖尿病患者下面的肝的 mitochondrial 机能障碍状态,和这可能与它 mitochondrial 的规定有关熔化和分裂事件。 | Zhimeng Xu Luyong Zhang Xiaojie Li Zhenzhou Jiang Lixin Sun Guolin Zhao Guohua Zhou Heran Zhang Jing Shang Tao Wang | 2015 | Acta Biochimica et Biophysica Sinica2015,47,9: | 4 |
| 3 | SEMIPARAMETRIC ANALYSIS OF ISOTONIC ERRORS-IN-VARIABLES REGRESSION MODELS WITH RANDOMLY RIGHT CENSORED RESPONSE显示文摘This paper considers the estimation of a semiparametric isotonic regression model when the covariates are measured with additive errors and the response is randomly right censored by a censoring time.The authors show that the proposed estimator of the regression parameter is rootn consistent and asymptotically normal.The authors also show that the isotonic estimator of the functional component,at a fixed point,is cubic root-n consistent and converges in distribution to the slope at zero of the greatest convex minorant of the sum of a two-sided standard Brownian motion and the square of the time parameter.A simulation study is carried out to investigate the performance of the estimators proposed in this article. | SUN Zhimeng ZHANG Zhongzhan DU Jiang | 2013 | Journal of Systems Science & Complexity2013,26,3: | 3 |
| 4 | Note: Low Genetic Variation of Penaeus chinensis as Revealed by Mitochondrial COI and 16S rRNA Gene Sequences显示文摘 | Jiexia Quan Xue-mei Lü Zhimeng Zhuang Jixun Dai Jingyao Deng Ya-ping Zhang | 2001 | Biochemical Genetics (-)2001,,7: | 1 |
| 5 | Synergistic actions of complement and lysozyme in clearance of Escherichia coli from amphioxus Branchiostoma belcheri显示文摘Amphioxus appears to lack free circulating blood cells. How it clears invading pathogens from its body remains unknown to date. We demonstrate here that amphioxus Branchiostoma belcheri is capable of efficiently eliminating the invading bacterium Escherichia coli from its humoral fluid,and the complement and lysozyme are both involved in the elimination of the invading pathogen. Both the com-plement and lysozyme act in concert against the invading bacterium,but the complement appears to play a more dominant role than the lysozyme. | Guangfeng Wang Shicui Zhang Zhimeng Zhuang Zhiping Wang | 2009 | Progress in Natural Science:Materials International2009,19,2: | 1 |
| 6 | C-banding pattern and nucleolar organizer regions of Cynoglossus semilaevis Günther, 1873显示文摘乐队 C 模式和 Cynoglossus semilaevis 的中期染色体的核仁的组织者区域被报导。在包括性染色体的对的所有染色体的 interstital 区域有积极 C 乐队,和 6 th 和第 12 个染色体完全在大多数情况中被染色。一些染色体例如第一,第二,第 7,第 8,第 9 和第 10 对在 centromeric 或远侧的结束显示出 C 乐队。染色质占据的到此为止的乐队 C 30.03% 全部的染色体出现在 C。semilaevis,它类似于象 Mixophyes fasciolatus (30.2%) 和 M 那样的两栖动物的。schevilli (20.7%) ,但是比头索动物 Branchiostoma belcher i (54.3%) 的相当低。银染色揭示了位于染色体 2 的 telomeric 区域的核仁的组织者区域(NORs ) 的单个对。有在脊椎动物观察的异种染色质的 NORs 的协会也发生在 C。染色体 2 的 telomeric 区域总是是的半 laevisas 与乐队 C 断然染色了。 | WU Di ZHANG Shicui ZHUANG Zhimeng PANG Qiuxiang WANG Changliu WAN Ruijing | 2006 | Progress in Natural Science:Materials International2006,16,7: | 1 |
| 7 | Protochordate amphioxus is an emerging model organism for comparative immunology显示文摘Protochordate amphioxus is an extant invertebrate regarded quite recently as a basal chordate. It has a vertebrate-like body plan including a circulation system with an organization similar to that of vertebrates. However, amphioxus is less complex than vertebrates for having a genome uncomplicated by extensive genomic duplication, and lacking lymphoid organs and free circulating blood cells. Recent studies on immunity have demonstrated the presence in amphioxus of both the constituent elements of key molecules involved in adaptive immunity such as proto-major histocompatibility complex (proto-MHC), V region-containing chitin-binding protein (VCBP) and V and C domain-bearing protein (VCP), and the complement system operating via the alternative and lectin pathways resembling those seen in vertebrates. In addition, the acute phase response profile in amphioxus has been shown to be similar to that observed in vertebrates. These findings together with the relative structural and genomic simplicity make amphioxus an ideal organism for gaining insights into the origin and evolution of the vertebrate immune system, especially adaptive immunity, and the composition and mech- anisms of the vertebrate innate immunity. | Shicui Zhang Yujun Liang Guangdong Ji Zhimeng Zhuang | 2009 | Progress in Natural Science:Materials International2009,19,8: | 1 |
| 8 | An active phase locking of multiple fiber channels via square wave dithering algorithm 显示文摘 | Xuan Tang Zhimeng Huang Dayong Zhang et aL | 2014 | Opt Commun2014,321,: | 1 |
| 9 | Synthesis of SrTiO_3 for immobilization of simulated HLW by SHS显示文摘Strontium titanate synroc samples were synthesized by self-propagating high-temperature synthesis (SHS). Sr directly took part in the synthesis process. As a result, the loading content issue is basically resolved. The products were characterized by density, microhardness X-ray diffraction, and scanning electron microscopy (SEM/EDS). The leaching rate was measured by the method of PCT (product consistency test). The results indicate that the Sr2+-SrTiO3 compound is of high density, low leach rate and high stability and the synthesis process is feasible in technology and economy. It can be concluded that the strontium titanate synroc is a perfect material to immobilize HLW. | Ruizhu Zhang junjie Hao Zhimeng Guo | 2005 | Journal of University of Science and Technology Beijing2005,12,4: | 1 |
| 10 | Synthesis of nanosized tungsten powder显示文摘Nanosized tungsten powder was synthesized by means of different methods and under different conditions with nanosized WO3 powder. The powder and the intermediate products were characterized using XRD, SEM, TEM, BET (Brunauer Emmett Teller Procedure) and SAXS (X-ray diffracto-spectrometer/Kratky small angle scattering goniometer). The results show that nanosized WO3 can be completely reduced to WO2 at 600℃ after 40 min, and WO2 can be reduced to W at 700℃ after 90 min, moreover, the mean size of W particles is less than 40 nm. Furthermore, the process of WO3→WO2→W excelled that of WO3→W in getting stable nanosized tungsten powder with less grain size. | Guangfeng Lu Junjie Hao Zhimeng Guo Ruizhu Zhang Ji Luo Liying Zhang | 2005 | Journal of University of Science and Technology Beijing2005,12,4: | 1 |
| 11 | VARIABLE SELECTION FOR PARTIALLY LINEAR VARYING COEFFICIENT QUANTILE REGRESSION MODEL显示文摘 | JIANG DU ZHONGZHAN ZHANG ZHIMENG SUN | 2013 | International Journal of Biomathematics2013,6,3: | 1 |
| 12 | Magnetically accelerated thermal energy storage within Fe_(3)O_(4)-anchored MXene-based phase change materials显示文摘Inherent weak photon-capturing ability is a long-standing bottleneck for pristine phase change materials(PCMs)in photothermal conversion application.To conquer this difficulty,herein,magnetic Fe_(3)O_(4) nanoparticles were in situ anchored between the layers and the surface of two-dimensional MXene for the infiltration of myristic acid(MA)by an in situ chemical anchoring strategy.Benefiting from the synergistic localized surface plasmon resonance effect of MXene and Fe_(3)O_(4) nanoparticles,our designed MXene@Fe_(3)O_(4)-MA composite PCMs harvested an ultrahigh photothermal conversion efficiency of 97.7%.During the photothermal conversion process,MXene can capture photons and convert solar energy into heat energy efficiently,and the in situ anchored Fe_(3)O_(4) nanoparticles further enhanced the photothermal conversion efficiency.Moreover,the introduction of Fe_(3)O_(4) nanoparticles improved the thermal energy storage density(144.17 J/g)of MXene-MA composite PCMs since Fe_(3)O_(4) nanoparticles provided more heterogeneous nucleation sites for MA.Simultaneously,MXene@Fe_(3)O_(4)-MA composite PCMs were endowed with excellent paramagnetism,and realized efficient magnetic-thermal conversion.Additionally,MXene@Fe_(3)O_(4)-MA composite PCMs exhibited excellent energy conversion stability,thermal stability,and reliability after undergoing multiple thermal cycles.Therefore,high-performance MXene@Fe_(3)O_(4)-based energy conversion composite PCMs are promising candidates to accelerate efficient utilization of the practical solar energy and magnetic energy. | Yan Gao Zhaodi Tang Xiao Chen Jiamin Yan Yu Jiang Jianhang Xu Zhang Tao Lei Wang Zhimeng Liu Ge Wang | 2023 | Aggregate2023,4,1: | 0 |
| 13 | Molecular sieve based Janus separators for Li-ions redistribution to enable stable lithium deposition显示文摘During operation of a lithium metal battery,uneven lithium deposition often results in the growth of lithium dendrites and causes a rapid decay in battery performance and even leads to safety issues.This is still the main hurdle hindering the practical application of lithium metal anodes.We report a new type of Janus separator fabricated by introducing a molecular sieve coating on the surface of the polypropylene separator that serves as a redistribution layer for lithium ions.Our results show that using this layer,the growth of lithium dendrites can be largely inhibited and the battery performance greatly improved.In a typical Li||Cu half-cell with the Janus separator,the Coulombic efficiency of the lithium metal anode can be maintained at>98.5%for over 500 cycles.The cycling life span is also extended by a factor of 8 in the Li||Li symmetric cell.Furthermore,the high-strength coating improves the mechanical properties of the separator,thus enhancing safety.The effectiveness of our strategy is demonstrated by both the inhibited growth of lithium dendrites and the improved battery performance.Our methodology could eventually be generalized for electrode protection in other battery systems. | Huanyu Xie Zhimeng Hao Shuai Xie Yadong Ye Wei Zhang Zhaowei Sun Song Jin Hengxing Ji Jun Chen | 2022 | Nano Research2022,15,6: | 0 |
| 14 | The effects of amino groups and open metal sites of MOFs on polymer-based electrolytes for all-solid-state lithium metal batteries显示文摘Metal-organic frameworks(MOFs) are becoming more and more popular as the fillers in polymer electrolytes in recent years. In this study, a series of MOFs(NH_(2)-MIL-101(Fe), MIL-101(Fe), activated NH_(2)-MIL-101(Fe) and activated MIL-101(Fe)) were synthesized and added to PEO-based solid composite electrolytes(SCEs). Furthermore, the role of the —NH_(2) groups and open metal sites(OMSs) were both examined. Different ratios of MOFs vs polymers were also studied by the electrochemical characterizations. At last, we successfully designed a novel solid composite electrolyte containing activated NH_(2)-MIL-101(Fe),PEO, Li TFSI and PVDF for the high-performance all-solid-state lithium-metal batteries. This work might provide new insight to understand the interactions between polymers and functional groups or OMSs of MOFs better. | Jiahao Lu Zhimeng Wang Qi Zhang Cheng Sun Yanyan Zhou Sijia Wang Xiangyun Qiu Shoudong Xu Rentian Chen Tao Wei | 2023 | Chinese Journal of Chemical Engineering2023,60,8: | 0 |
| 15 | Commissioning experiment of the high-contrast SILEX-Ⅱ multi-petawatt laser facility显示文摘The results of a commissioning experiment on the SILEX-Ⅱlaser facility(formerly known as CAEP-PW)are reported.SILEX-Ⅱis a complete optical parametric chirped-pulse amplification laser facility.The peak power reached about 1 PWin a 30 fs pulse duration during the experiment.The laser contrast was better than 1010 at 20 ps ahead of the main pulse.In the basic laser foil target interaction,a set of experimental data were collected,including spatially resolved x-ray emission,the image of the coherent transition radiation,the harmonic spectra in the direction of reflection,the energy spectra and beam profile of accelerated protons,hot-electron spectra,and transmitted laser energy fraction and spatial distribution.The experimental results show that the laser intensity reached 531020 W/cm^(2) within a 5.8μm focus(FWHM).Significant laser transmission did not occur when the thickness of theCHfoil was equal to or greater than 50 nm.The maximum energy of the accelerated protons in the target normal direction was roughly unchanged when the target thickness varied between 50 nm and 15μm.The maximum proton energy via the target normal sheath field acceleration mechanism was about 21 MeV.We expect the on-target laser intensity to reach 10^(22) W/cm^(2) in the near future,after optimization of the laser focus and upgrade of the laser power to 3 PW. | Wei Hong Shukai He Jian Teng Zhigang Deng Zhimeng Zhang Feng Lu Bo Zhang Bin Zhu Zenghai Dai Bo Cui Yuchi Wu Dongxiao Liu Wei Qi Jinlong Jiao Faqiang Zhang Zuhua Yang Feng Zhang Bi Bi Xiaoming Zeng Kainan Zhou Yanlei Zuo Xiaojun Huang Na Xie Yi Guo Jingqin Su Dan Han Ying Mao Leifeng Cao Weimin Zhou Yuqiu Gu Feng Jing Baohan Zhang Hongbo Cai Minqing He Wudi Zheng Shaoping Zhu Wenjun Ma Dahui Wang Yinren Shou Xueqing Yan Bin Qiao Yi Zhang Congling Zhong Xiaohui Yuan and Wenqing Wei | 2021 | Matter and Radiation at Extremes2021,6,6: | 0 |
| 16 | Laser compression via fast-extending plasma gratings显示文摘A method is proposed for compressing laser pulses by fast-extending plasma gratings(FEPGs),which are created by ionizing a hypersonic wave generated by stimulated Brillouin scattering in a background gas.Ionized by a short laser pulse,the phonon forms a light-velocity FEPG to fully reflect a resonant pump laser.As the reflecting surface moves with the velocity of light,the reflected pulse is temporally overlapped and compressed.One-and two-dimensional fully kinetic particle-in-cell simulations with a laser wavelength of 1μm show that in this regime,a pump pulse is compressed from 10–40 ps to 7–10 fs(i.e.,a few optical cycles),with a two-dimensional transfer efficiency up to 60%.This method is a promising way to produce critical laser powers while avoiding several significant problems that arise in plasma-based compressors,including an unwanted linear stage,major plasma instabilities,and the need for seed preparation. | Zhaohui Wu Yanlei Zuo Xiaoming Zeng Zhaoli Li Zhimeng Zhang Xiaodong Wang Bilong Hu Xiao Wang Jie Mu Jingqin Su Qihua Zhu Yaping Dai | 2022 | Matter and Radiation at Extremes2022,7,6: | 0 |