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| 1 | Porcine growth differentiation factor 9 gene polymorphisms and their associations with litter size显示文摘Growth differentiation factor 9 (GDF9) is expressed in oocytes and is thought to be required for ovarian folliculogenesis. Given this function, GDF9 may be considered as a candidate gene controlling pig ovulate rate. In this study, the complete coding sequence was cloned (encoding a 444 amino acid), intron sequence and partial 5′-UTR of pig GDF9. RT-PCR results showed that GDF9 mRNA is expressed in a wide range of tissues of the ruttish Erhualian pig. The expression levels of GDF9 mRNA in pituitary, ovary, uterus and ovi-duct are higher in the Erhualian pigs than those in Duroc pigs, especially in pituitary with a significant difference (P< 0.05). Comparative sequencing revealed 12 polymorphisms, including 8 single nucleotide polymorphisms (SNPs) and one 314 bp indel in noncoding regions, and the other 3 SNPs in coding regions. Four polymorphisms, G359C, C1801T, T1806C and 314 bp indel, were developed as markers for further use in population variation and association studies. The G359C polymorphism segregates only in Chinese native pigs, Erhualian and Dahuabai, on the contrary, 314 bp indel segregates only in Duroc and Landrace. C1801T and T1806C sites seem to be completely linked and segregate in Erhualian, Dahuabai and Landrace. In a word, GDF9 may be not associated with pig litter size in extensive popu-lations as per the studies of allele distributions of the four polymorphisms and pilot association in four breeds. | Yushan Zhang Hongli Du Jing Chen Guanfu Yang Xiquan Zhang | 2008 | Journal of Genetics and Genomics2008，35，3： | 4 |
| 2 | Modification of ADP extinguishing powder by siliconization in spray drying显示文摘Superfine spherical fire-extinguishing powder,ammonium dihydrogen phosphate(ADP,NH4H2PO4),was prepared by spray drying and modified in situ with methyl hydrogen silicone oil(MHSO)emulsion and the fluorinated surfactant FK-510.The influences of the MHSO mass ratio on the hydrophobicity,surface composition,surface morphology,dispersion and particle-size distribution of the NH4H2PO4 were studied,and the influence of the drying air temperature on the decomposition of the NH4H2PO4 was also researched.The results indicate that the MHSO and FK-510 congregate on the particle surfaces and then form a hydrophobic shell.This shell improves the particle hydrophobicity and leads to a fine dispersion of the particles.During the process of preparing the precursor solution,3 wt%(based on the weight of NH4H2PO4)was chosen as the optimum value of the MHSO mass ratio.During the spray drying,a low absolute humidity of the air should be maintained,and it is very important to keep the exit-air temperature below 100°C to avoid decomposition. | Xiaojing Zhang ZhigangShen Chujiang Cai Xiaozheng Yu Jun Du Yushan Xing Shulin Ma | 2012 | Particuology2012，10，4： | 2 |
| 3 | A chromosome-level genome assembly of rugged rose (Rosa rugosa) provides insights into its evolution, ecology, and floral characteristics显示文摘Rosa rugosa,commonly known as rugged rose,is a perennial ornamental shrub.It produces beautiful flowers with a mild fragrance and colorful seed pods.Unlike many other cultivated roses,R.rugosa adapts to a wide range of habitat types and harsh environmental conditions such as salinity,alkaline,shade,drought,high humidity,and frigid temperatures.Here,we produced and analyzed a high-quality genome sequence for R.rugosa to understand its ecology,floral characteristics and evolution.PacBio HiFi reads were initially used to construct the draft genome of R.rugosa,and then Hi-C sequencing was applied to assemble the contigs into 7 chromosomes.We obtained a 382.6Mb genome encoding 39,704 protein-coding genes.The genome of R.rugosa appears to be conserved with no additional whole-genome duplication after the gamma whole-genome triplication(WGT),which occurred~100 million years ago in the ancestor of core eudicots.Based on a comparative analysis of the high-quality genome assembly of R.rugosa and other high-quality Rosaceae genomes,we found a unique large inverted segment in the Chinese rose R.chinensis and a retroposition in strawberry caused by post-WGT events.We also found that floral development-and stress response signaling-related gene modules were retained after the WGT.Two MADS-box genes involved in floral development and the stress-related transcription factors DREB2A-INTERACTING PROTEIN 2(DRIP2)and PEPTIDE TRANSPORTER 3(PTR3)were found to be positively selected in evolution,which may have contributed to the unique ability of this plant to adapt to harsh environments.In summary,the high-quality genome sequence of R.rugosa provides a map for genetic studies and molecular breeding of this plant and enables comparative genomic studies of Rosa in the near future. | Fei Chen Liyao Su Shuaiya Hu Jia-Yu Xue Hui Liu Guanhua Liu Yifan Jiang Jianke Du Yushan Qiao Yannan Fan Huan Liu Qi Yang Wenjie Lu Zhu-Qing Shao Jian Zhang Liangsheng Zhang Feng Chen Zong-Ming(Max)Cheng | 2021 | Horticulture Research2021，8，1： | 2 |
| 4 | Regulation of mATG9 trafficking by Src- and ULK1mediated phosphorylation in basal and starvation-induced autophagy显示文摘Autophagy 要求多样的膜来源并且包含 mATG9 的膜 trafficking,在 ATG 家庭的唯一的膜蛋白质。然而,为 autophagy 开始的 mATG9 trafficking 的分子的规定仍然保持不清楚。这里,我们识别了在 mATG9 的 cytosolic N 终点以内排序信号的二保存经典适配器蛋白质,它调停从经由和 AP1/2 建筑群的相互作用的血浆膜和 trans-Golgi 网络(TGN ) 的 mATG9 的 trafficking。在 Tyr8 到的 Src phosphorylates mATG9 处于不着重的条件维持它的 endocytic 和组成的 trafficking。响应饥饿,在由 Src 的 Tyr8 并且在由 ULK1 的 Ser14 的 mATG9 的 phosphorylation 机能上地合作支持在 mATG9 和 AP1/2 建筑群之间的相互作用,为 autophagy 从血浆膜和 juxta 原子的区域导致 mATG9 的再分配到外部水池开始。我们的调查结果揭开 mATG9 trafficking 的新奇机制并且建议基础、导致压力的 autophagy 的协作。 | Changqian Zhou Kaili Ma Ruize Gao Chenglong Mu Linbo Chen Qiangqiang Liu Qian Luo Du Feng Yushan Zhu Quan Chen | 2017 | Cell Research2017，27，2： | 2 |
| 5 | Molecular characteristics of S-RNase alleles as the determ inant of self-i ncompatibility in the style of Fragaria viridi显示文摘Strawberry(Fragaria spp.)is a member of the Rosoideae subfamily in the family Rosaceae.The self-incompatibility(SI)of some diploid species is a key agronomic trait that acts as a basic pollination barrier;however,the genetic mechanism underlying SI control in strawberry remains unclear.Two candidate S-RNases(S a-and S^-RNase)identi fi ed in the transcriptome of the styles of the self-incompatible Fragaria viridis 42 were con fi rmed to be SI determinants at the S locus following genotype identi fi cation and intraspeci fi c hybridization using sel fi ng progenies.Whole-genome collinearity and RNase T2 family analysis revealed that only an S locus exists in Fragaria;however,none of the compatible species contained S-RNase.Although the results of interspeci fi c hybridization experiments showed that F.viridis(SI)styles could accept pollen from F.mandshurica(self-compatible),the reciprocal cross was incompatible.S a and S b-RNase contain large introns,and their noncoding sequences(promotors and introns)can be transcribed into long noncoding RNAs(lncRNAs).Overall,the genus Fragaria exhibits S-RNase-based gametophytic SI,and S-RNase loss occurs at the S locus of compatible germplasms.In addition,a type of SI-independent unilateral incompatibility exists between compatible and incompatible Fragaria species.Furthermore,the large introns and neighboring lncRNAs in S-RNase in Fragaria could offer clues about S-RNase expression strategies. | Jianke Du Chunfeng Ge Tingting Li Sanhong Wang Zhihong Gao Hidenori Sassa Yushan Qiao | 2021 | Horticulture Research2021，8，1： | 1 |
| 6 | Genome-wide identification and co-expression analysis of GDSL genes related to suberin formation during fruit russeting in pear显示文摘Glycine-aspartic acid–serine-leucine(GDSL)type lipases/esterases genes play critical roles in plant development and are related to the responses to abiotic and biotic stress.However,little is known about the GDSL family in pear(Pyrus spp.).Studies have shown GDSL-domain proteins play key roles in suberin deposition.Suberin deposition in the fruit epidermis,also called russeting,is an important defect that negatively affects consumer's appeal in some fruit species,such as pear,apple and grapevine.Fruit russeting is mainly associated with cuticle microcracking and suberin accumulation in the inner part of the epidermal cell walls.To gain insight into the role of the GDSL gene family in suberin deposition and russet development in pear,we performed a genome-wide characterization of the GDSL family,including their identification,chromosomal localization,phylogenetic relationships,and expression patterns,in different tissues/organs in pear.One hundred and thirteen GDSL-type lipases/esterases genes were identified in the pear genome,and a phylogenetic analysis revealed that GDSL family can be classified into four distinct groups.Thirty GDSL genes were co-expressed with five homolog pear genes of three well-known suberin biosynthesis Arabidopsis genes(AtGPAT5,AtASFT,and AtCYP86B1)in the transcriptional co-expression network during pear fruit development.Among the 30 co-expressed GDSL genes,twelve genes were further analyzed by quantitative Real-time PCR,and the results showed the expression levels of the 12 genes were different between the russet exocarp and green exocarp of sand pear at different fruit development stages.Our study provides a detailed overview of the GDSL gene family and lays the foundation for future functional characterization of GDSL genes in P.bretschneideri. | Pujuan Zhang Hong Zhang Jianke Du Yushan Qiao | 2022 | Horticultural Plant Journal2022，8，2： | 1 |
| 7 | CO_(2)methanation boosted by support-size-dependent strong metal-support interaction and B-O-Ti component显示文摘Strong metal-support interaction(SMSI)has a great impact on the activity and selectivity of heterogeneous catalysts,which was usually adjusted by changing reduction temperature or processing catalyst in different atmosphere.However,few researches concentrate on modulating SMSI through regulating the structure of the support.Herein,we show how changing the surface environment of the anatase TiO_(2)(B–TiO_(2))can be used to modulate the SMSI.The moderate TiOx overlayer makes the Ni metal highly dispersed on the high specific surface area of support,resulting in a substantially enhanced CO_(2)methanation rate.Besides,a novel phenomenon was observed that boron dopants promote the for-mation of the B–O–Ti interface site,enhancing the catalytic performance of CO_(2)hydrogenation.DFT calculations confirm that the B–O–Ti structure facilitates the activation of CO_(2)and further hydrogenation to methane. | Shaoyu Yuan Yushan Yang Zhangyi Xiong Peijing Guo Sufang Sun Zejiang Li Jianlong Du Yongjun Gao | 2024 | Green Energy & Environment2024，9，2： | 0 |
| 8 | Effect modifications of BMI transition and trajectory in the associations of adverse childhood experiences with new-onset dementia and its subtypes in older US adults显示文摘Background Adverse childhood experiences(ACEs)and dementia are associated and comorbid with obesity.However,according to emerging research,the role of obesity in the association between ACEs and dementia seems controversial.Aims This analysis aimed to explore the associations between ACEs and different dementia subtypes and the effect modification of long-term body mass index(BMI).Methods Data were obtained from the US Health and Retirement Study.Six ACEs were categorised as 0,1 and 2 or more.All-cause dementia,Alzheimer’s disease(AD)and other dementias were defined by self-reported or proxy-reported physician diagnosis.Cox proportional hazards regression was used to explore the associations of ACEs with new-onset all-cause dementia,AD and other dementias from 2010 to 2020.Effect modification of BMI in 2010 and BMI transition and trajectory(fitted by group-based trajectory modelling)from 2004 to 2010 were assessed.Results 15282 participants with a mean age of 67.0 years(58.0–75.0)were included in the 2010 data analysis.Significant interactions of ACEs with baseline BMI,BMI transition and BMI trajectory in their associations with new-onset all-cause dementia and AD were observed(all p<0.05).For instance,positive associations of two or more ACEs(vs none)with all-cause dementia and AD were found in those with a BMI trajectory of maintaining≥30 kg/m2(maintain obesity)rather than a decline to or maintaining<25 kg/m2(decline to or maintain normal weight),with hazard ratios(HRs)of 1.87(95%confidence interval(CI):1.45 to 2.42)and 1.85(95%CI:1.22 to 2.80),respectively.Conclusions ACEs were associated with dementia and AD in US adults with long-term abnormally elevated BMI but not with long-term normal or decreasing BMI.Integrated weight management throughout life could prevent dementia among those with childhood adversity. | Ziyang Ren Binbin Su Yushan Du Tianjing Zhou Xiaoying Zheng Jufen Liu | 2023 | General Psychiatry2023，36，4： | 0 |
| 9 | Photothermal superhydrophobic copper nanowire assemblies: fabrication and deicing/defrosting applications显示文摘Ice and frost buildup continuously pose significant challenges to multiple fields.As a promising de-icing/defrosting alternative,designing photothermal coatings that leverage on the abundant sunlight source on the earth to facilitate ice/frost melting has attracted tremendous attention recently.However,previous designs suffered from either localized surface heating owing to the limited thermal conductivity or unsatisfied meltwater removal rate due to strong water/substrate interaction.Herein,we developed a facile approach to fabricate surfaces that combine photothermal,heat-conducting,and superhydrophobic properties into one to achieve efficient de-icing and defrosting.Featuring copper nanowire assemblies,such surfaces were fabricated via the simple template-assisted electrodeposition method,allowing us to tune the nanowire assembly geometry by adjusting the template dimensions and electrodeposition time.The highly ordered copper nanowire assemblies facilitated efficient sunlight absorption and lateral heat spreading,resulting in a fast overall temperature rise to enable the thawing of ice and frost.Further promoted by the excellent water repellency of the surface,the thawed ice and frost could be spontaneously and promptly removed.In this way,the all-in-one design enabled highly enhanced de-icing and defrosting performance compared to other nanostructured surfaces merely with superhydrophobicity,photothermal effect,or the combination of both.In particular,the defrosting efficiency could approach∼100%,which was the highest compared to previous studies.Overall,our approach demonstrates a promising path toward designing highly effective artificial deicing/defrosting surfaces. | Siyan Yang Qixun Li Bingang Du Yushan Ying Yijun Zeng Yuankai Jin Xuezhi Qin Shouwei Gao Steven Wang Zuankai Wang Rongfu Wen Xuehu Ma | 2023 | International Journal of Extreme Manufacturing2023，5，4： | 0 |
| 10 | Periconceptional Folic Acid Only Versus Multiple Micronutrients Containing Folic Acid and Association with Gestational Diabetes Mellitus-Beijing Municipality,China,2017-2021显示文摘Summary What is already known about this topic?Inconsistent results have been reported on the association between periconceptional folic acid only(FAO)or multiple micronutrients containing folic acid(MMFA)supplementation and the risk of gestational diabetes mellitus(GDM)in previous research.What is added by this report?In a prospective cohort study conducted among pregnant women in Haidian District,Beijing Municipality,it was observed that those who took MMFA demonstrated a higher likelihood of developing GDM in comparison to those who consumed FAO periconceptionally.Interestingly,the increased risk for GDM in pregnant women supplemented with MMFA compared to FAO was primarily due to changes in fasting plasma glucose.What are the implications for public health practice?It is highly recommended that women prioritize the use of FAO in order to yield potential benefits in the prevention of GDM. | Shuangbo Xia Yushan Du Ziyang Ren Jinjuan Zhang Suhong Gao Jiamei Wang Zhiwen Li Xiaohong Liu Jufen Liu | 2023 | China CDC weekly2023，5，23： | 0 |
| 11 | The effect of Lorentz-like force on collective flows of K+in Au+Au collisions at 1.5 Ge V/nucleon显示文摘Producing kaon mesons in heavy-ion collisions at beam energies below their threshold energy is an important way to investigate the properties of dense nuclear matter. In this study, based on the newly updated version of the ultrarelativistic quantum molecular dynamics model, we introduce the kaon-nucleon(KN) potential, including both the scalar and vector(also dubbed Lorentz-like)aspects. We revisit the influence of the KN potential on the collective flow of K+mesons produced in Au+Au collisions at Elab= 1.5 Ge V/nucleon and find that the contribution of the newly included Lorentz-like force is very important, particulary for describing the directed flow of K+. Finally, the corresponding Kao S data of both directed and elliptic flows can be simultaneously reproduced well. | YuShan Du YongJia Wang QingFeng Li Ling Liu | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，6： | 0 |
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