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| 1 | Tumor differentiation phenotype in gastric differentiated-type tumors and its relation to tumor invasion and genetic alterations显示文摘瞄准:在胃的区分类型的肿瘤澄清在肿瘤区别显型和肿瘤侵略或基因改变之间的关系。方法:我们检验了肿瘤区别在 48 个胃的腺瘤和 171 区分类型的癌的显型,在 APC 和 p53 的变化的存在,和微卫星不稳定性(MSI ) 地位。肿瘤区别显型被检验人的表示决定胃粘蛋白(HGM ) , MUC6, MUC2 和 CD10。肿瘤然后被分类进胃 --(G-) ,胃、肠混合 --( 官方补给 --) ,或肠 --( 我 --) 显型,根据上述标记的免疫确实。在 APC 和 p53 和 MSI 地位的变化的存在也在所有肿瘤被调查。结果:胃的腺瘤显著地与 CD10 表示,我显型肿瘤和 APC 变化的存在被联系,与癌相比(66.7% 对 25.1% , P <
0.0001;56.3% 对 14.6% , P <
0.0001;39.6% 对 14.0% , P <
0.0001,分别地) 并且相反地与 HGM 和 MUC6 和 p53 变化的存在的表情联系了(10.4% 对 62.6% , P <
0.0001;39.6% 对 64.3% , P = 0.003;2.0% 对 26.3% , P = 0.001,分别地) 。APC 变化的频率在比在 HGM 积极的肿瘤, MUC6 积极的肿瘤, CD10 否定的肿瘤和 G 显型肿瘤的 HGM 否定的肿瘤, MUC6 否定的肿瘤, CD10 积极的肿瘤和我显型肿瘤是显著地更高的(32.7% 对 7.1% , P <
0.0001;27.8% 对 14.0% , P = 0.0182;37.3% 对 10.4% , P <
0.0001;并且 38.5% 对 9.5% , P = 0.0017,分别地) 。MSI 的频率在比在 MUC6 否定的肿瘤, CD10 积极的肿瘤和我显型肿瘤的 MUC6 积极的肿瘤, CD10 否定的肿瘤和 G 显型肿瘤是显著地更高的(24.8% 对 6.7% , P = 0.0009;22.2% 对 8.0% , P = 0.0143;并且 28.6% 对 9.6% , P = 0.0353,分别地) 。结论:肿瘤区别显型是仔细与在胃的区分类型的肿瘤的肿瘤侵略和基因改变有关。 | Kimiyasu Yamazaki Yusuke Tajima Reiko Makino Nobukazu Nishino Shigeo Aoki Masanori Kato Masaaki Sakamoto Koji Morohara Tsutomu Kaetsu Mitsuo Kusano | 2006 | World Journal of Gastroenterology2006，12，24： | 9 |
| 2 | Sentinel Node Mapping Guided by Indocyanine Green Fluorescence Imaging in Gastric Cancer显示文摘 | Yusuke Tajima Kimiyasu Yamazaki Yuki Masuda Masanori Kato Daisuke Yasuda Takeshi Aoki Takashi Kato Masahiko Murakami Mitsuharu Miwa Mitsuo Kusano | 2009 | Annals of Surgery2009，，1： | 3 |
| 3 | Risk Factors for Lymph Node Metastasis from Gastric Cancers with Submucosal Invasion显示文摘 | Yusuke Tajima Masahiko Murakami Kimiyasu Yamazaki Yuki Masuda Shigeo Aoki Masanori Kato Atsushi Sato Satoru Goto Koji Otsuka Takashi Kato | 2010 | Annals of Surgical Oncology2010，，6： | 2 |
| 4 | Sentinel Node Mapping Guided by Indocyanine Green Fluorescence Imaging in Gastric Cancer显示文摘 | Yusuke Tajima Kimiyasu Yamazaki Yuki Masuda Masanori Kato Daisuke Yasuda Takeshi Aoki Takashi Kato Masahiko Murakami Mitsuharu Miwa Mitsuo Kusano | 2009 | Annals of Surgery2009，，1： | 1 |
| 5 | Weekly paclitaxel for heavily treated advanced or recurrent gastric cancer refractory to fluorouracil, irinotecan, and cisplatin显示文摘 | Rai Shimoyama Hirofumi Yasui Narikazu Boku Yusuke Onozawa Shuichi Hironaka Akira Fukutomi Kentaro Yamazaki Keisei Taku Takashi Kojima Nozomu Machida Akiko Todaka Hideharu Tomita Takeshi Sakamoto Takahiro Tsushima | 2009 | Gastric Cancer2009，，4： | 1 |
| 6 | HLA-Cw*1202-B*5201-DRB1*1502 Haplotype Increases Risk for Ulcerative Colitis but Reduces Risk for Crohn’s Disease显示文摘 | Yukinori Okada Keiko Yamazaki Junji Umeno Atsushi Takahashi Natsuhiko Kumasaka Kyota Ashikawa Tomomi Aoi Masakazu Takazoe Toshiyuki Matsui Atsushi Hirano Takayuki Matsumoto Naoyuki Kamatani Yusuke Nakamura Kazuhiko Yamamoto Michiaki Kubo | 2011 | Gastroenterology2011，，3： | 1 |
| 7 | Seasonal Changes in Runoff Characteristics on a Permafrost Watershed in the Southern Mountainous Region of Eastern Siberia显示文摘 | Yusuke Yamazaki | 2006 | Hydrological Process2006，20，： | 1 |
| 8 | Surgical Results for Functional Univentricular Heart With Total Anomalous Pulmonary Venous Connection Over a 25-Year Experience显示文摘 | Yuki Nakayama Takeshi Hiramatsu Yusuke Iwata Toru Okamura Takeshi Konuma Goki Matsumura Kenji Suzuki Kyoko Hobo Toshio Nakanishi Hiromi Kurosawa Kenji Yamazaki | 2012 | The Annals of Thoracic Surgery2012，，2： | 1 |
| 9 | Safety of bevacizumab treatment in combination with standard chemotherapy for metastatic colorectal cancer: a retrospective review of 65 Japanese patients显示文摘 | Akihiro Tamiya Kentaro Yamazaki Narikazu Boku Nozomu Machida Takashi Kojima Keisei Taku Hirofumi Yasui Akira Fukutomi Shuichi Hironaka Yusuke Onozawa | 2009 | International Journal of Clinical Oncology2009，，6： | 1 |
| 10 | Electrically polarized micro-arc oxidized TiO 2 coatings with enhanced surface hydrophilicity显示文摘 | Chufan Ma Akiko Nagai Yuko Yamazaki Takeshi Toyama Yusuke Tsutsumi Takao Hanawa Wei Wang Kimihiro Yamashita | 2011 | Acta Biomaterialia2011，，2： | 1 |
| 11 | Characterization of Trichoderma polysporum from Spitsbergen, Svalbard archipelago, Norway, with species identity, pathogenicity to moss, and polygalacturonase activity显示文摘 | Yusuke Yamazaki Motoaki Tojo Tamotsu Hoshino Kenichi Kida Tatsuji Sakamoto Hideshi Ihara Isao Yumoto Anne Marte Tronsmo Hiroshi Kanda | 2010 | Fungal Ecology2010，，1： | 1 |
| 12 | Airborne electromagnetic and magnetic surveys for long tunnel construction design显示文摘 | Kenji Okazaki Toru Mogi Mitsuru Utsugi Yoshihiko Ito Hideki Kunishima Takashi Yamazaki Yukitsugu Takahashi Takeshi Hashimoto Yusuke Ymamaya Hisatoshi Ito Hideshi Kaieda Kazuhiro Tsukuda Youichi Yuuki Akira Jomori | 2011 | Physics and Chemistry of the Earth2011，，16： | 1 |
| 13 | Association analysis of SLC22A4, SLC22A5 and DLG5 in Japanese patients with Crohn disease显示文摘 | Keiko Yamazaki Masakazu Takazoe Torao Tanaka Toshiki Ichimori Susumu Saito Aritoshi Iida Yoshihiro Onouchi Akira Hata Yusuke Nakamura | 2004 | Journal of Human Genetics2004，，12： | 1 |
| 14 | Association analysis of SLC22A4, SLC22A5 and DLG5 in Japanese patients with Crohn disease显示文摘 | Keiko Yamazaki Masakazu Takazoe Torao Tanaka Toshiki Ichimori Susumu Saito Aritoshi Iida Yoshihiro Onouchi Akira Hata Yusuke Nakamura | 2004 | Journal of Human Genetics2004，，12： | 1 |
| 15 | Sentinel Node Mapping Guided by Indocyanine Green Fluorescence Imaging During Laparoscopic Surgery in Gastric Cancer显示文摘 | Yusuke Tajima Masahiko Murakami Kimiyasu Yamazaki Yuki Masuda Masanori Kato Atsushi Sato Satoru Goto Koji Otsuka Takashi Kato Mitsuo Kusano | 2010 | Annals of Surgical Oncology2010，，7： | 1 |
| 16 | A Safeguard System for Induced Pluripotent Stem Cell-Derived Rejuvenated T Cell Therapy显示文摘 | Miki Ando Toshinobu Nishimura Satoshi Yamazaki Tomoyuki Yamaguchi Ai Kawana-Tachikawa Tomonari Hayama Yusuke Nakauchi Jun Ando Yasunori Ota Satoshi Takahashi Ken Nishimura Manami Ohtaka Mahito Nakanishi John J. Miles Scott R. Burrows Malcolm K. Brenner Hi | 2015 | Stem Cell Reports2015，，4： | 1 |
| 17 | Association analysis of SLC22A4, SLC22A5 and DLG5 in Japanese patients with Crohn disease显示文摘 | Keiko Yamazaki Masakazu Takazoe Torao Tanaka Toshiki Ichimori Susumu Saito Aritoshi Iida Yoshihiro Onouchi Akira Hata Yusuke Nakamura | 2004 | Journal of Human Genetics2004，，12： | 1 |
| 18 | Safety and efficacy of S-1 monotherapy in elderly patients with advanced gastric cancer显示文摘 | Takahiro Tsushima Shuichi Hironaka Narikazu Boku Nozomu Machida Kentaro Yamazaki Hirofumi Yasui Keisei Taku Akira Fukutomi Yusuke Onozawa | 2010 | Gastric Cancer2010，，4： | 1 |
| 19 | Association analysis of SLC22A4, SLC22A5 and DLG5 in Japanese patients with Crohn disease显示文摘 | Keiko Yamazaki Masakazu Takazoe Torao Tanaka Toshiki Ichimori Susumu Saito Aritoshi Iida Yoshihiro Onouchi Akira Hata Yusuke Nakamura | 2004 | Journal of Human Genetics2004，，12： | 1 |
| 20 | Development of a digital zenith telescope for advanced astrometry显示文摘Like other optical astrometric techniques,the Photographic Zenith Tube(PZT) has played a key role in the past observations of the Earth rotation,and it also has a potential to be applied to several other observations by taking advantage of automatic observations with self compensation of tilt of the tube.We here propose In-situ Lunar Orientation Measurement(ILOM) to study lunar rotational dynamics by direct observations of the lunar rotation from the lunar surface by using a small telescope like PZT with an accuracy of 1 milli-seconds of arc(1 mas) in the post-SELENE mission.Our second application is to obtain local gravity field on the Earth by combining deflection of the vertical measured by PZT and the position measured by Global Positioning System(GPS) or Global Navigation Satellite System(GNSS).The accuracy required for this purpose is not as strict as ILOM.We have already developed a Bread Board Model(BBM) of the telescope for ILOM and made some experiments in order to know the performance of the driving mechanism under a similar condition to the lunar environment showing high vacuum,large temperature change and dusty condition.We have also shown that it is possible to correct the effects of uniform temperature change upon the optical system by using a simple model with an accuracy of better than 1 mas.This model has the potential to attain the accuracy of 1 mas,based on the results of the experiments and the simulations. | HANADA Hideo ARAKI Hiroshi TAZAWA Seiichi TSURUTA Seiitsu NODA Hirotomo ASARI Kazuyoshi SASAKI Sho FUNAZAKI Ken'ichi SATOH Atsushi TANIGUCHI Hideo KIKUCHI Mamoru TAKAHASHI Tomoe YAMAZAKI Atsumu PING JinSong KAWANO Nobuyuki PETROVA Natalia GOUDA Naoteru YANO Taihei YAMADA Yoshiyuki NIWA Yoshito KONO Yusuke IWATA Takahiro | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，4： | 1 |
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