|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Natural orifice transluminal endoscopic surgery in urology: The Chinese experience显示文摘Objective:To describe the Chinese experience of natural orifice transluminal endoscopic surgery(NOTES)in urology.Methods:From December 2008 to May 2017,35 animal experiments and 305 clinical surgeries of NOTES or natural orifices specimen extractions(NOSE)were performed in China.The animal experiments included five kidney biopsies,24 nephrectomies and six partial nephrectomies.The clinical surgeries included 12 transvaginal NOSE(TV-NOSE),266 hybrid transvaginal NOTES(TV-NOTES)and 27 pure TV-NOTES.The TV-NOSE procedure was performed in five transumbilical laparoendoscopic single-site(U-LESS)nephrectomies,four suprapubic-assisted laparoendoscopic single-site surgery(SA-LESS)nephroureterectomies,and three laparoscopic radical cystectomies.The hybrid TV-NOTES procedure included 210 nephrectomies,31 adrenalectomies,eight nephroureterectomies,13 partial nephrectomies,and four heminephrectomies.The pure TV-NOTES procedure included five renal cyst decortications and 22 nephrectomies.Results:A total of 29 animal experiments were successfully performed.One partial nephrectomy was converted to standard laparoscopic surgery.Two kidney biopsies and two nephrectomies were unsuccessful.A total of 297 clinical surgeries were successfully performed.Six patients who underwent hybrid TV-NOTES were converted to open surgery.Two patients who underwent pure TV-NOTES were converted to SA-LESS.There were 22 major complications,16 occurred intraoperatively and six postoperatively.The mean visual analog score(VAS)of 48 h after the operation was 2.5 points in TV-NOSE,2.3 points in hybrid TV-NOTES and 1.7 points in pure TV-NOTES.The mean follow-up of 50.6(3.0-87.0)months showed that all patients were in good condition.The umbilicus scars were nearly invisible in TV-NOSE and hybrid TV-NOTES.The vaginal incision healed well.Conclusions:TV-NOSE and TV-NOTES are feasible,safe,and effective with little injury,low pain,fast recovery,and good cosmetic outcomes in properly selected patients.They are worth consideration for urological clinical practice. | Xiaofeng Zou Guoxi Zhang Tianpeng Xie Yuanhu Yuan Rihai Xiao Gengqing Wu Xiaoning Wang Hui Xu Folin Liu Yuting Wu Yunfeng Liao Quanliang Liu Yinghao Sun Bo Yang Linhui Wang Chuanliang Xu Xiaofeng Gao | 2020 | Asian Journal of Urology2020，7，1： | 5 |
| 2 | Purely organic optoelectronic materials with ultralong-lived excited states under ambient conditions显示文摘The exponential growth of utilizing synthetic organic molecules in optoelectronic applications poses strong demands for rational control over the excited states of the materials. The manipulation of excited states through molecular design has led to the development of high-performance optoelectronic devices with tunable emission colors, high quantum efficiencies and efficient energy/charge transfer processes. Recently, a significant breakthrough in lifetime tuning of excited states has been made;the purely organic molecules were found to have ultralonglived excited state under ambient conditions with luminescence lifetimes up to 1.35 s, which are several orders of magnitude longer than those of conventional organic fluorophores. Given the conceptual advance in understanding the fundamental behavior of excited state tuning in organic luminescent materials, the investigations of organic ultralong room-temperature phosphorescence(OURTP) should provide new directions for researches and have profound impacts on many different disciplines. Here, we summarized the recent understandings on the excited state tuning, the reported OURTP molecules and their design considerations,the spectacular photophysical performance, and the amazing optoelectronic applications of the newly emerged organic optoelectronic materials that free of heavy metals. | Jie Yuan Yuting Tang Shen Xu Runfeng Chen Wei Huang | 2015 | Science Bulletin2015，60，19： | 4 |
| 3 | Reconstruction the Process of Partial Melting of the Retrograde Eclogite from the North Qaidam,Western China: Constraints from Titanite U-Pb Dating and Mineral Chemistry显示文摘Retrograde eclogite and garnet amphibolite of the Lüliangshan unit of the Shenglikou area,North Qaidam,were studied with emphasis on rutile and titanite.A special focus is on the formation of rutile and its corona of titanite(Ttn1)in retrograde eclogite and on coarse-grained titanite(Ttn2)from the garnet amphibolite.Using zirconium(Zr)-in-rutile and Zr-in-titanite thermometers,the temperatures estimated for the formation of an early generation of rutile are 823–884℃at 2.5–2.8 GPa,while 812–894℃at 1.3–1.5 GPa are derived for the formation of coronitic Ttn1 in the retrograde eclogite.Therefore,isothermal decompression must have occurred during exhumation,which also has triggered the partial melting of the retrograde eclogite.Ttn2 of the garnet amphibolite has high REE contents and high Th/U ratios,indicating that it is newly grown from a Ti,Ca,and LREE enriched anatectic melt derived from the partial melting of retrograde eclogite.LA-ICP MS U-Pb dating yields a lower intercept age of 423±4 Ma for Ttn2,which is consistent with the granulite-facies metamorphic age of the retrograde eclogite.Moreover,a temperature of 781–823℃at 1.0–1.2 GPa is obtained for Ttn2,which fits the P-T conditions of the HP granulite-facies metamorphic stage(P=1.07–1.24 GPa and T=774–814℃),and documents that the crystallization of the melt occurred at the granulite-facies stage at 423 Ma.The high amount of REE of the garnet amphibolite is a consequence of the formation of Ttn2 from the melt.The contents and ratios of Zr and Hf in rutile and Ttn2 differ from those in the garnet amphibolite,and the whole rock Zr/Hf ratios of retrograde eclogite and garnet amphibolite are both higher than the respective ratios in rutile and Ttn2,suggesting that rutile and titanite cannot be the major carriers of Zr and Hf accounting for the high whole rock Zr/Hf ratios. | Yuting Cao Liang Liu Wenqiang Yang Yuan Gao Xiaohui Zhu | 2019 | Journal of Earth Science2019，30，6： | 4 |
| 4 | Effect of pH on N 2 O reduction and accumulation during denitrification by methanol utilizing denitrifiers显示文摘 | Yuting Pan Liu Ye Bing-Jie Ni Zhiguo Yuan | 2012 | Water Research2012，，15： | 2 |
| 5 | Characterization and Expression Analysis of Protein Kinase C Gene from Dunaliella salina显示文摘Protein kinase C (PKC) has a crucial role in signal transduction for a variety of biologically active substances which activate cellular functions and proliferation. We previously isolated the full-length PKC gene from Dunaliella salina (DsPKC) using rapid amplification of cDNA ends (RACE) and RT-PCR methods. And we submitted the mRNA sequence of DsPKC gene to NCBI (Genbank No. JN625213). In the present paper, the DsPKC gene open reading frame obtained by PCR was cloned into pGS-21a vector and transformed into Escherichia coli to generate the fusion protein. Bioinformatics analysis revealed that DsPKC gene was a member of serine/threonine kinase with two conserved domains and highly conserved motifs. The DsPKC was highly expressed upon induction with isopropyl-β-d-thiogalactoside (IPTG) at a final concentration of 0.2 mmol L 1 at 37℃. Under salt stress, the fu- sion protein Green Fluorescent Protein (GFP)-DsPKC was transferred from the cytoplasm to the cell membrane. The expression pat- tern of DsPKC gene was analyzed using real-time quantitative PCR, and indicated that DsPKC gene was up-regulated by 3.0 mol L 1 NaCl at 12 h, which was significantly higher than in control values (P < 0.05). These results suggest that the DsPKC gene plays an important role in response to salt stress in D. salina. | CONG Yuting MA Yuexin WANG Yuan LIU Yiqiong CHAI Xiaojie | 2019 | Journal of Ocean University of China2019，18，4： | 2 |
| 6 | Suprapubic‐assisted laparoendoscopic single‐site surgery ( LESS ) in urology: our experience显示文摘 | Xiaofeng Zou Guoxi Zhang Yijun Xue Yuanhu Yuan Rihai Xiao Gengqing Wu Xiaoning Wang Yuting Wu Dazhi Long Jun Yang Hui Xu Folin Liu Xu Zhang | 2013 | BJU Int2013，，2： | 1 |
| 7 | Drop dis- tributions and numerical simulation of dropwise condensa- tion heat transfer 显示文摘 | WU Yuting YANG Chunxin YUAN Xiugan | 2001 | International Journal of Heat and Mass Transfer2001，44，23： | 1 |
| 8 | Improvement of Coenzyme Q10 Production: Mutagenesis Induced by High Hydrostatic Pressure Treatment and Optimization of Fermentation Conditions显示文摘 | Yahong Yuan Yuting Tian Tianli Yue Andrei Surguchov | 2012 | Journal of Biomedicine and Biotechnology2012，，： | 1 |
| 9 | Angular momentum holography via a minimalist metasurface for optical nested encryption显示文摘Metasurfaces can perform high-performance multi-functional integration by manipulating the abundant physical dimensions of light,demonstrating great potential in high-capacity information technologies.The orbital angular momentum(OAM)and spin angular momentum(SAM)dimensions have been respectively explored as the independent carrier for information multiplexing.However,fully managing these two intrinsic properties in information multiplexing remains elusive.Here,we propose the concept of angular momentum(AM)holography which can fully synergize these two fundamental dimensions to act as the information carrier,via a single-layer,non-interleaved metasurface.The underlying mechanism relies on independently controlling the two spin eigenstates and arbitrary overlaying them in each operation channel,thereby spatially modulating the resulting waveform at will.As a proof of concept,we demonstrate an AM meta-hologram allowing the reconstruction of two sets of holographic images,i.e.,the spin-orbital locked and the spin-superimposed ones.Remarkably,leveraging the designed dual-functional AM meta-hologram,we demonstrate a novel optical nested encryption scheme,which is able to achieve parallel information transmission with ultra-high capacity and security.Our work opens a new avenue for optionally manipulating the AM,holding promising applications in the fields of optical communication,information security and quantum science. | Hui Yang Peng He Kai Ou Yueqiang Hu Yuting Jiang Xiangnian Ou Honghui Jia Zhenwei Xie Xiaocong Yuan Huigao Duan | 2023 | Light(Science & Applications)2023，12，4： | 1 |
| 10 | The influence of public perception on risk acceptance of the chemical industry and the assistance for risk communication显示文摘 | Lei Huang Jie Ban Kai Sun Yuting Han Zengwei Yuan Jun Bi | 2013 | Safety Science2013，，1： | 1 |
| 11 | Identification of Persister Drug Combination Clinafloxacin+Cefuroxime+Gentamicin That Eradicates Persistent Pseudomonas aeruginosa Infection in a Murine Cystic Fibrosis Model显示文摘Pseudomonas aeruginosa can cause persistent infections,such as biofilm infections,in cystic fibrosis patients,which are difficult to cure due to non-growing persister bacteria that are not effectively killed by the current treatments.While antibiotic activity against growing P.aeruginosa is well documented,their activity against non-growing stationary phase cultures is less clear.Here,we evaluated six major classes of antibiotics,including cell wall and cell membrane inhibitors,protein synthesis inhibitors,DNA synthesis inhibitors,RNA synthesis inhibitors,sulfa drugs and nitrofurantoin,for their activity against growing and non-growing P.aeruginosa.We foundthat cell wall and cell membrane inhibitors(cefuroxime and colistin),DNA synthesis inhibitors(clinafloxacin)and sulfa drugs(sulfamethoxazole)had good activity against stationary-phase bacteria,while protein synthesis inhibitors(gentamicin),RNA synthesis inhibitor(rifampin)and nitrofurantoin showed relatively poor activity.Clinafloxacin was the only drug able to completely eradicate stationary-phase bacteria within four days.The cefuroxime+gentamicin+clinafloxacin combination was able to kill all bacteria from a biofilm within two days,whereas the clinically used drug combination cefuroxime+gentamicin/colistin only partially killed the biofilmbacteria.In amurine persistent cystic fibrosis lung infectionmodel,only the cefuroxime+gentamicin+clinafloxacin drug combination eradicated all bacteria from the lungs,whereas clinafloxacin alone,cefuroxime+clinafloxacin or the currently recommended drug combination cefuroxime+gentamicin failed to do so.The complete eradication is a property of the clinafloxacin combination,as the otherwise identical levofloxacin combination did not clear the bacterial loads from the lungs.Our findings offer new therapeutic options for more effective treatment of persistent P.aeruginosa infections,with possible implications for treating other persistent infections. | Yuting Yuan Rebecca Yee Naina Gour Xinzhong Dong Jie Feng Wanliang Shi Ying Zhang | 2023 | Infectious Microbes & Diseases2023，5，1： | 1 |
| 12 | Nitrous oxide emissions from wastewater treatment processes显示文摘 | Yingyu Law Liu Ye Yuting Pan Zhiguo Yuan | 2012 | Philosophical Transactions of the Royal Society B2012，，1593： | 1 |
| 13 | Designing and deploying a mixed-reality aquarium for cognitive training of young children with autism spectrum disorder显示文摘Autism spectrum disorder(ASD),a developmental disorder severely affecting cognition and social behavior,is increasing in prevalence[1].This increasing trend is especially severe in children,making the early intervention crucial to ASD treatment.Children with ASD have been found impairments in several aspects of cognition functions. | Juan LIU Yulong BIAN Yanran YUAN Yuting XI Wenxiu GENG Xinpei JIN Wei GAI Xiangmin FAN Feng TIAN Xiangxu MENG Chenglei YANG | 2021 | Science China(Information Sciences)2021，64，5： | 1 |
| 14 | Heritable expansion of the genetic code in mouse and zebrafish显示文摘 | Yuting Chen Ji Ma Wenqing Lu Meilin Tian Marion Thauvin Chonggang Yuan Michel Volovitch Qian Wang Jeff Holst Mingyao Liu Sophie Vriz Shixin Ye Lei Wang Dali Li | 2017 | Cell Research2017，27，2： | 1 |
| 15 | Flexible Hf_(0.5)Zr_(0.5)O_(2)ferroelectric thin films on polyimide with improved ferroelectricity and high flexibility显示文摘Flexible memory devices are promising for information storage and data processing applications in portable,wearable,and smart electronics operating under curved conditions.In this work,we realized high-performance flexible ferroelectric capacitors based on Hf_(0.5)Zr_(0.5)O_(2)(HZO)thin film by depositing a buffer layer of Al_(2)O_(3)on polyimide(PI)substrates using atomic layer deposition(ALD).The flexible ferroelectric HZO films exhibit high remnant polarization(Pr)of 21μC/cm^(2).Furthermore,deterioration of polarization,retention,and endurance performance was not observed even at a bending radius of 2 mm after 5,000 bending cycles.This work marks a critical step in the development of high-performance flexible HfO_(2)-based ferroelectric memories for next-generation wearable electronic devices. | Yuting Chen Yang Yang Peng Yuan Pengfei Jiang Yuan Wang Yannan Xu Shuxian Lv Yaxin Ding Zhiwei Dang Zhaomeng Gao Tiancheng Gong Yan Wang Qing Luo | 2022 | Nano Research2022，15，4： | 1 |
| 16 | Drop distributions and numerical simulation of dropwise condensation heat transfer显示文摘 | WU Yuting YANG Chunxin YUAN Xiugan | 2001 | Int J Heat Mass Transfer2001，44，23： | 1 |
| 17 | Polarimetric parity-time symmetry in a photonic system显示文摘Parity-time(PT)symmetry has attracted intensive research interest in recent years.PT symmetry is conventionally implemented between two spatially distributed subspaces with identical localized eigenfrequencies and complementary gain and loss coefficients.The implementation is complicated.In this paper,we propose and demonstrate that PT symmetry can be implemented between two subspaces in a single spatial unit based on optical polarimetric diversity.By controlling the polarization states of light in the single spatial unit,the localized eigenfrequencies,gain,loss,and coupling coefficients of two polarimetric loops can be tuned,leading to PT symmetry breaking.As a demonstration,a fiber ring laser based on this concept supporting stable and single-mode lasing without using an ultranarrow bandpass filter is implemented. | Lingzhi Li Yuan Cao Yanyan Zhi Jiejun Zhang Yuting Zou Xinhuan Feng Bai-Ou Guan Jianping Yao | 2020 | Light(Science & Applications)2020，9，1： | 1 |
| 18 | Milk-derived exosomes as a promising vehicle for oral delivery of hydrophilic biomacromolecule drugs显示文摘Exosomes,as promising vehicles,have been widely used in the research of oral drug delivery,but the generally low drug loading efficiency of exosomes seriously limits its application and transformation.In this study,we systematically investigated the effects of drug loading methods and physicochemical properties(lipophilicity and molecular weight)on drug loading efficiency of milk-derived exosomes to explore the most appropriate loading conditions.Our finding revealed that the drug loading efficiency of exosomes was closely related to the drug loading method,drug lipophilicity,drug molecular weight and exosome/drug proportions.Of note,we demonstrated the universality that hydrophilic biomacromolecule drugs were the most appropriate loading drugs for milk-derived exosomes,which was attributed to the efficient loading capacity and sustained release behavior.Furthermore,milk-derived exosomes could significantly improve the transepithelial transport and oral bioavailability of model hydrophilic biomacromolecule drugs(octreotide,exendin-4 and salmon calcitonin).Collectively,our results suggested that the encapsulation of hydrophilic biomacromolecule drugs might be the most promising direction for milk exosomes as oral drug delivery vehicles. | Yuting Li Liyun Xing Lingling Wang Xi Liu Licheng Wu Mingjie Ni Zhou Zhou Lian Li Xiuxiu Liu Yuan Huang | 2023 | Asian Journal of Pharmaceutical Sciences2023，18，2： | 1 |
| 19 | Sex differences of brain cortical structure in major depressive disorder显示文摘Background:Major depressive disorder(MDD)has different clinical presentations in males and females.However,the neuroanatom-ical mechanisms underlying these sex differences are not fully understood.Objective:The purpose of present study was to explore the sex differences in brain cortical thickness(CT)and surface area(SA)of MDD and the relationship between these differences and clinical manifestations in different gender.Methods:High-resolution T1-weighted images were acquired from 61 patients with MDD and 61 healthy controls(36 females and 25 males,both).The sex differences in CT and SA were obtained using the FreeSurfer software and compared between every two groups by post hoc test.Spearman correlation analysis was also performed to explore the relationships between these regions and clinical characteristics.Results:In male patients with MDD,the CT of the right precentral was thinner compared to female patients,although this did not survive Bonferroni correction.The SA of several regions,including right superior frontal,medial orbitofrontal gyrus,inferior frontal gyrus triangle,superior temporal,middle temporal,lateral occipital gyrus,and inferior parietal lobule in female patients with MDD was smaller than that in male patients(P<0.01 after Bonferroni correction).In female patients,the SA of the right superior temporal(r=0.438,P=0.008),middle temporal(r=0.340,P=0.043),and lateral occipital gyrus(r=0.372,P=0.025)were positively correlated with illness duration.Conclusion:The current study provides evidence of sex differences in CT and SA in patients with MDD,which may improve our understanding of the sex-specific neuroanatomical changes in the development of MDD. | Jingping Mou Ting Zheng Zhiliang Long Lan Mei Yuting Wang Yizhi Yuan Xin Guo Hongli Yang Qiyong Gong Lihua Qiu | 2023 | Psychoradiology2023，3，1： | 0 |
| 20 | Counteracting lineage-specific transcription factor network finely tunes lung adeno-to-squamous transdifferentiation through remodeling tumor immune microenvironment显示文摘Human lung adenosquamous cell carcinoma(LUAS),containing both adenomatous and squamous pathologies,harbors strong plasticity and is significantly associated with poor prognosis.We established an up-to-date comprehensive genomic and transcriptomic landscape of LUAS in 109 Chinese specimens and demonstrated LUAS development via adeno-to-squamous transdifferentiation.Unsupervised transcriptomic clustering and dynamic network biomarker analysis identified an inflammatory subtype as the critical transition stage during LUAS development.Dynamic dysregulation of the counteracting lineage-specific transcription factors(TFs),containing adenomatous TFs NKX2-1 and FOXA2,and squamous TFs TP63 and SOX2,finely tuned the lineage transition via promoting CXCL3/5-mediated neutrophil infiltration.Genomic clustering identified the most malignant subtype featured with STK11-inactivation,and targeting LSD1 through genetic deletion or pharmacological inhibition almost eradicated STK11-deficient lung tumors.These data collectively uncover the comprehensive molecular landscape,oncogenic driver spectrum and therapeutic vulnerability of Chinese LUAS. | Shijie Tang Yun Xue Zhen Qin Zhaoyuan Fang Yihua Sun Chongzhe Yuan Yunjian Pan Yue Zhao Xinyuan Tong Jian Zhang Hsinyi Huang Yuting Chen Liang Hu Dasong Huang Ruiqi Wang Weiguo Zou Yuan Li Roman KThomas Andrea Ventura Kwok-Kin Wong Haiquan Chen Luonan Chen Hongbin Ji | 2023 | National Science Review2023，10，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员