|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Task-related functional magnetic resonance imaging-based neuronavigation for the treatment of depression by individualized repetitive transcranial magnetic stimulation of the visual cortex显示文摘To determine whether repetitive transcranial magnetic stimulation(rTMS)of the visual cortex(VC)provides effective and welltolerated treatment and whether magnetic resonance imaging(MRI)measures functional change of the VC as a biomarker of therapeutic effect in major depressive disorder(MDD),we performed a sham-controlled,double-blind,randomized,three-arm VC rTMS treatment study in 74 MDD patients.Neuronavigated rTMS(10 Hz,90%of resting motor threshold,1,600 pulses over20 min twice per day)was performed over the VC for five days.Clinical outcome was measured by Hamilton Depression Rating Scale(HAMD-24)at days 0,1,3,5 and after terminating rTMS,with follow-up at four weeks.MRI was measured at days 0 and5.The individualized group exhibited the greatest change in HAMD-24 scores after VC rTMS for 5 days(F=5.53,P=0.005),which were maintained during follow-up period(F=4.22,P=0.016).All patients reported good tolerance.Changes in VC taskrelated functional MRI correlated with symptomatic reduction in the individualized group.Treatment reduced the initially abnormal increase in resting state functional connectivity from the VC to the pre/subgenual anterior cingulate cortex at day 5,especially in the individualized group.We demonstrated therapeutic potential and good tolerance of VC rTMS in MDD patients,indicated by biomarkers of f MRI measurement. | Zhijun Zhang Hongxing Zhang Chun-Ming Xie Meng Zhang Yachen Shi Ruize Song Xiang Lu Haisan Zhang Kun Li Bi Wang Yongfeng Yang Xianrui Li Jianli Zhu Yang Zhao Ti-Fei Yuan Georg Northoff | 2021 | Science China(Life Sciences)2021，64，1： | 8 |
| 2 | Tribological properties of nanometer cerium oxide as additives in lithium grease显示文摘This paper presents a comparative study of the influence of nanometer-CeO_2(nano-CeO_2) and temperature on tribological and lubricating properties of lithium grease. The morphology and structure of nanocrystals were characterized by means of transmission electron microscopy(TEM) and X-ray diffraction(XRD), respectively. Friction and wear tests were conducted on the friction and wear tester.Results show that the lithium grease with addition of nanometer-CeO_2 has much better friction-reducing and anti-wear performance than that of base grease. When the additive in grease is 0.6 wt%, the friction coefficient(COF) and wear scar diameter(WSD) decrease by 28% and 13% comparing with base grease,respectively. The base grease and grease with 0.6 wt% nanometer-CeO_2 both possess the lowest average COF and wear width at 50 ℃. The worn surface morphology after friction test was analyzed by scanning electron microscopy(SEM) and NANOVEA three-dimensional profilometer. Under the lubrication of the lithium grease containing 0.6 wt% nano-CeO_2. few shallow furrows can be observed on the quite smoothed surface and the WSD decreased. Moreover, It was found that the nano-CeO_2 has been incorporated into the surface protective and lubricious layer by energy dispersive spectrometer(EDS) analysis. | Qiang He Anling Li Yachen Guo Songfeng Liu Yong Zhang Linghao Kong | 2018 | Journal of Rare Earths2018，36，2： | 6 |
| 3 | Nucleic acid nanoassembly-enhanced RNA therapeutics and diagnosis显示文摘RNAs are involved in the crucial processes of disease progression and have emerged as powerful therapeutic targets and diagnostic biomarkers.However,efficient delivery of therapeutic RNA to the targeted location and precise detection of RNA markers remains challenging.Recently,more and more attention has been paid to applying nucleic acid nanoassemblies in diagnosing and treating.Due to the flexibility and deformability of nucleic acids,the nanoassemblies could be fabricated with different shapes and structures.With hybridization,nucleic acid nanoassemblies,including DNA and RNA nanostructures,can be applied to enhance RNA therapeutics and diagnosis.This review briefly introduces the construction and properties of different nucleic acid nanoassemblies and their applications for RNA therapy and diagnosis and makes further prospects for their development. | Mengnan Zhao Rujing Wang Kunmeng Yang Yuhong Jiang Yachen Peng Yuke Li Zhen Zhang Jianxun Ding Sanjun Shi | 2023 | Acta Pharmaceutica Sinica B2023，13，3： | 2 |
| 4 | Oxidized LowDensity lipoprotein and C-Reactive protein have combined utility for better predicting prognosis after acute coronary syndrome显示文摘 | ZHANG Yachen TANG Yong CHEN Yu | 2014 | Cell Biochemistry and Biophysics2014，68，2： | 1 |
| 5 | Photo Responsive Silver Nanoparticles Incorporated Liquid Crystalline Elastomer Nanocomposites Based on Surface Plasmon Resonance显示文摘 | ZHANG Jindi WANG Jun ZHAO Lina YANG Wenlong BI Meng WANG Yuchang NIU Hongyan LI Yuxin WANG Binsong GAO Yachen LI Chensha HUANG Xuezhen | 2017 | Chemical Research in Chinese Universities2017，33，5： | 1 |
| 6 | Synthesis and nonlinear optical properties of reduced graphene oxide hybrid material covalently functionalized with zinc phthalocyanine显示文摘 | Weina Song Chunying He Wang Zhang Yachen Gao Yixiao Yang Yiqun Wu Zhimin Chen Xiaochen Li Yongli Dong | 2014 | Carbon2014，，： | 1 |
| 7 | Effects of Gurney flaps on a NACA0012 airfoil显示文摘 | Li Yachen Wang Jinjun Zhang Panfeng | 2002 | Flow Turbulence and Combustion2002，68，1： | 1 |
| 8 | VAV2 is required for DNA repair and implicated in cancer radiotherapy resistance显示文摘Radiotherapy remains the mainstay for treatment of various types of human cancer;however,the clinical efficacy is often limited by radioresistance,in which the underlying mechanism is largely unknown.Here,using esophageal squamous cell carcinoma(ESCC)as a model,we demonstrate that guanine nucleotide exchange factor 2(VAV2),which is overexpressed in most human cancers,plays an important role in primary and secondary radioresistance.We have discovered for the first time that VAV2 is required for the Ku70/Ku80 complex formation and participates in non-homologous end joining repair of DNA damages caused by ionizing radiation. | Weiling Liu Chuanwang Miao Shaosen Zhang Yachen Liu Xiangjie Niu Yiyi Xi Wenjia Guo Jiahui Chu Ai Lin Hongjin Liu Xinyu Yang Xinjie Chen Ce Zhong Yuling Ma Yuqian Wang Shihao Zhu Shuning Liu Wen Tan Dongxin Lin Chen Wu | 2021 | Signal Transduction and Targeted Therapy2021，6，9： | 1 |
| 9 | High-mainte-nance-dose clopidogrel in patients undergoing percutaneous coronary intervention= a systematic review and meta-analysis 显示文摘 | Chen Yu Zhang YaChen Tang Yong | 2013 | PLoS One2013，8，78： | 1 |
| 10 | Formation kinetics of polyoxymethylene dimethyl ethers from methylal and trioxane with little water显示文摘Polyoxymethylene dimethyl ethers(CH_(3)-O-(CH_(2)O)_(n)-CH_(3),PODE_(n),n>1)can be added to diesel to reduce air pollution caused by incomplete combustion.Driven by this need,a cost-effective and efficient synthetic route is presented and investigated by this work for the production of PODE_(n),which are formed from methylal and trioxane with low water content(<10%(mass))over HZSM-5 catalyst in a batch slurry autoclave at the temperature from 353.15 K to 393.15 K.The reaction rate laws including the PODE_(n) and byproducts of polyoxymethylene hemiformals(HF_(n)),polyoxymethylene glycols(MG),methanol(MeOH)and methyl formate(MF)are developed.The rate constants of propagation step(k_(6))and depolymerization step(k_(-6))are assumed independent on polymerization degree of PODE_(n).The rate of reaction is proportional to the content of the catalyst(Wcat)for the catalytic reaction within the scope of the study.All kinetic parameters were estimated by combining genetic algorithm and least square regression to fit experimental data well.This work is valuable for process optimization and reactor design. | Xiaofei Qin Sen Lei Xubin Zhang Chen Cao Feng Xin Honglin Chen Xiaoming Zhang Yachen Yin Guilian Wu | 2021 | Chinese Journal of Chemical Engineering2021，34，5： | 0 |
| 11 | Nanomaterials for Cardiac Tissue Engineering Application显示文摘In recent years, the emerging cardiac tissue engineering provides a new therapeutic method for heart diseases. And in the tissue engineering, the scaffold material which can mimic the structure of the extracellular matrix properly is a key factor. The rapid expansion of nano-scaffolds during the past ten years has led to new perspectives and advances in biomedical research as well as in clinical practice. Here we search articles published in recent years extensively on cardiac tissue engineering scaffold materials and nanotechnology. And we review the traditional scaffold materials and the advances of the nano-scaffolds in cardiac tissue engineering. A thorough understanding of the nano-scaffolds would enable us to better exploit technologies to research the ideal scaffold material, and promote the cardiac tissue engineering using in the clinical practice as soon as possible. | Yachen Zhang Yong Tang Ying Wang Liying Zhang | 2011 | Nano-Micro Letters2011，3，4： | 0 |
| 12 | Effects of window opening style on inside environment of solar greenhouse based on CFD simulation显示文摘Solar greenhouse is extensively used in horticultural production in China.Natural ventilation is one of the key technological means to adjust the inside environment of greenhouse,while the effects of window opening styles on the inside environment are still not well understood.In the present study,the temperature and air flow field of five operation styles,namely back roof central opening style(G1),back roof evenly spaced opening style(G2),top roof full opening style(G3),style of G1+G3,and style of G2+G3 were simulated using the CFD method.The results indicated that:(1)the simulated and measured results exhibited favorable agreement,with relative errors within 5%;(2)In the case of the windows opening area was the same and only single ventilation style was applied,back roof full opening style exhibited the best cooling effect.The inside average temperature of the greenhouse with G1 style decreased by 0.5°C and 1.6°C respectively compared with those of greenhouses with G2 and G3.(3)The cooling effect of the style of G2+G3 was more favorable than that of the style of G1+G3.The style of G2+G3 exhibited better cooling effect than the single ventilation styles,with the lowest temperature(27.5°C)and temperature uniformity coefficient(0.36). | Yachen Sun Encai Bao Chenmeng Zhu Lulu Yan Yanfei Cao Xuanhe Zhang Jianming Li Haiwei Jing Zhirong Zou | 2020 | International Journal of Agricultural and Biological Engineering2020，13，6： | 0 |
| 13 | Dual-band dynamic reconfigurable intelligent surface for signal enhancement in millimeter wave显示文摘Millimeter wave with large bandwidth,high transmission rate,and low delay is considered a reliable alternative to cope with the spectrum shortage.However,the fast attenuation and narrow beam characteristics make it difficult to achieve long-distance or wide-range applications.Here,a 1-bit dual-band reflective reconfigurable intelligent surface(RIS)for signal enhancement in millimeter wave with 16×16 elements is designed,fabricated,and measured.Different from most existent RIS,dynamic programming is realized at two separate frequency bands by integrating the PIN diodes and field-programmable gate array(FPGA).Particularly,the beam deflection,dual-beam,and multi-beam are created based on the coding theory and convolution operation,proving the effectiveness of wavefront manipulation.Moreover,the far-field patterns and signal power with different coding sequences are measured and compared.It is indicated that the received signal power is 6–7 dB stronger than that without coding,which shows good agreement with the desired expectations.The proposed reconfigurable metasurface exhibits great potential in beam forming,making it a promising candidate for progressive wireless communication applications. | YAO HuiMing DU XinRun WANG HengBin GAO Song PANG YaChen ZHENG HaiRong GONG HuiWen LI Yi XU JianChun ZHANG JianHua BI Ke | 2024 | Science China(Technological Sciences)2024，67，4： | 0 |
| 14 | Switchable optical nonlinear properties of W_(18)O_(49) nanowires by Ag nanoparticles supported显示文摘During the past decades,nonlinear optical(NLO)materials have attracted special interest because of their potential applications in photonic devices,such as optical switching,frequency conversion and electro-optic modulators.Among the finding ways to obtain excellent NLO materials with both large NLO response and short response time,the most common approach is to design and prepare new | Yang Liu XueSong Xu Yang Chen ZhenYi Zhang YaChen Gao KuiChao Liu LiDong Gong Bin Dong | 2017 | Science China(Physics,Mechanics & Astronomy)2017，60，11： | 0 |
| 15 | Dynamic Study of Nonlinear Optical Properties in Tetrasodium Salt of Copper Tetrasulfophthalocyanine/Water Solution显示文摘 | Wang Zhang Chunying He Xiangwu Xiao Weina Song Yachen Gao Zhimin Chen Yongli Dong Yiqun Wu Qian Wang | 2016 | Chinese Journal of Chemistry2016，34，10： | 0 |
| 16 | The effect of Coulomb interaction on particle-antiparticle correlation function显示文摘Dear Editors,The quantitative interpretation of the particle and antiparticle correlation results depends critically on understanding the role of Coulomb interaction of the measured pairs of particles with each other,as well as the Coulomb interaction of the pair with the system of remaining particles[1-7]. | ShuXia Li YaChen Gao YongZhi Zhang ZiShi Jiang | 2016 | Science China(Physics,Mechanics & Astronomy)2016，59，7： | 0 |
| 17 | Research on angle-dependent to mographic static correction显示文摘Reflection data in CMP has influenced seriously in static calculations,especially in some highly weathered and structurally altered circumstances. Because of static correction in the existed problems and requests,the authors studied the angle dependent tomographic static correction,and discussed its basic theory, including the establishment of forward model,the calculation theory of tomography and tomographic static correction. The usage of theoretical models and practical information on the method has been validated. The results show that using these methods to calculate static correction in a complex area,the quality of static correction is greatly improved. | CHEN Guangyu LIU Yang WANG Kai ZHANG Yachen | 2012 | Global Geology2012，15，2： | 0 |
| 18 | Application performances of two greenhouses with new types of backwall in Yangling,China显示文摘In order to investigate the application performances of the solar greenhouses with new types of backwall(greenhouse W_(2),and greenhouse W_(3))and the ordinary clay brick backwall greenhouse(greenhouse W_(1)),and provide a theoretical basis for the construction of solar greenhouse in Yangling Demonstration Zone,Shaanxi,China,two greenhouses with different new types of backwall were designed.The backwall of one of them was built with lightweight aggregate concrete block(greenhouse W_(2))and that of the other one was assembled with a row of sand-filled cement pipes(greenhouse W_(3)).The tested greenhouses were constructed in Yangling Demonstration Zone.Based on the data collected on typical sunny and cloudy days,the indoor temperature,inside wall temperature,and the heat flow of the greenhouses with new types of backwall were compared with those detected in the ordinary clay brick backwall solar greenhouse,and the tested results were numerically simulated.According to the comparison of the physiological indicators of tomatoes planted in the greenhouses and the construction costs,the greenhouse type with the best practicability was found.The results indicated that:The average air temperature in greenhouses W_(1),W_(2),and W_(3)and outside was 15.1℃,15.9℃,17.3℃,and−0.4℃ on the night of a sunny day,and the air temperature in W_(3)was the highest.The average air temperature in greenhouses W_(1),W_(2),and W_(3)and outside were 9.5℃,13.3℃,11.0℃,and−5.5℃ on the night of a cloudy day,the air temperature in W_(2)was the highest.In the depth of 0-330 mm from the interface of the backwalls,the walls were obviously affected by the solar radiation,and the temperature changed greatly.The wall temperature on the sunny days exhibited an ascending order of W_(1),W_(2),W_(3),while on the cloudy days was in the ascending order of W_(1),W_(3),W_(2).The wall of W_(3)absorbed the most heat during the daytime and released the most heat at night on the sunny day,while W_(2)exhibited the second most heat absorption during the daytime,however,it exhibited the highest heat release at night on the cloudy day,which were almost equaled to its heat absorption.Tomatoes in W_(3)grew well and exhibited the highest yield,and this greenhouse had the lowest construction costs.Comprehensively considering the physiological indicators of tomatoes and the corresponding construction costs of greenhouses,W_(3)has the best application performance in Yangling Demonstration Zone. | Yachen Sun Haotian Wang Chenmeng Zhu Hongyi Lyu Xuanhe Zhang Yanfei Cao Jianming Li Zhirong Zou Encai Bao | 2022 | International Journal of Agricultural and Biological Engineering2022，15，3： | 0 |
| 19 | Sensitivity of solar greenhouse envelopes to the thermal disfigurements and optimal selection of the thermal insulation quilt显示文摘The objectives of the present work are focused on exploration of the reasons for temperature difference in different envelopes,the sensitivity of envelopes of solar greenhouse to thermal disfigurements and optimal selection of the thermal insulation quilt.Theoretical analysis and derivation are conducted according to the experimental results of surface temperature,convective heat transfer,and heat flux density in different envelopes which with thermal disfigurements of solar greenhouse using heat transfer theory.The results revealed that the difference of intrinsic thermal conductivity and thickness of the envelopes leads to difference in the thermal flux and thus in the surface temperature of different envelopes.Compared with the front roof and back roof,the wall is more sensitive to thermal disfigurements.According to the influence of thermal disfigurements on solar greenhouse temperature,the allowable thermal disfigurements area fraction of front roof and back roof are given.Based on the analysis of heat transfer theory and test results,the work given the expression of the thickness and thermal conductivity of thermal insulation quilt under different outdoor minimum temperatures for optimal selection of thermal insulation quilt based on comprehensive considering factors of the solar greenhouse structure,crop demand,outdoor minimum temperature,and insulation quilt properties.The results of this work give technical criterion for whether the envelopes with thermal disfigurements needs to be repaired or replaced,and it also provides theoretical and technical support for design the solar greenhouse as well as methodological guidance for the optimal selection of the thermal insulation quilt. | Yachen Sun Yao Zhang Chenmeng Zhu Shaonan Xu Bowen Liu Yanfei Cao Changji Zhou Yaqi Zhou Zhirong Zou Encai Bao | 2021 | International Journal of Agricultural and Biological Engineering2021，14，5： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员