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| 1 | Design, Synthesis and Biological Evaluation of Isothiazole Based 1,2,4-Trizaole Derivatives显示文摘 | Lai Chen Qifan Wu Zhijin Fan Hongpeng Li Jiwei Li Wenhao Hu Xiumei Liu Nataliya P Belskaya Tatiana Glukhareva Bin Zhao | 2018 | Chinese Journal of Chemistry2018，36，8： | 2 |
| 2 | Encapsulation of lyophilized platelet-rich fibrin in alginate-hyaluronic acid hydrogel as a novel vascularized substitution for myocardial infarction显示文摘Cardiovascular diseases such as myocardial infarction(MI)are among the major causes of death worldwide.Although intramyocardial injection of hydrogels can effectively enhance the ventricular wall,this approach is limited because of its restriction to the poor vascularization in the infarcted myocardium.Here,we reported a new type of hydrogel composed of alginate(ALG)and hyaluronic acid(HA)with lyophilized platelet-rich fibrin(Ly-PRF)for releasing abundant growth factors to realize their respective functions.The results of in vitro studies demonstrated favorable mechanical property and release ability of ALG-HA with Ly-PRF.When injected into the infarcted myocardium,this composite hydrogel preserved heart function and the Ly-PRF within the hydrogel promoted angiogenesis and increased vascular density in both infarcted and border zone,which rescued the ischemic myocardium.These beneficial effects were also accompanied by macrophage polarization and regulation of myocardial fibrosis.Moreover,the autologous origin of Ly-PRF with ALG-HA hydrogel offers myriad advantages including safety profile,easiness to obtain and cost-effectiveness.Overall,this study demonstrated the versatile therapeutic effects of a novel composite hydrogel ALG-HA with Ly-PRF,which optimizes a promising vascularized substitution strategy for improving cardiac function after MI. | Bei Qian Qi Yang Mingliang Wang Shixing Huang Chenyu Jiang Hongpeng Shi Qiang Long Mi Zhou Qiang Zhao Xiaofeng Ye | 2022 | Bioactive Materials2022，7，1： | 2 |
| 3 | Histone acetyltransferase p300 promotes MKLl-mediated transactivation of catechol-O-methyltransferase gene显示文摘以前的研究表明了 histone acetyltransferase p300 被招募到某些心脏、光滑的肌肉的倡导者特定的基因到提高 myocardin 的 transactivation 活动,它是在心血管的区别和开发的一个主人管理者。这里,我们发现编码 catechol-O-methyltransferase (COMT ) 的基因,催化雌激素的变换的重要的新陈代谢的酶,也是 myocardin 相关的抄写因素(MRTF ) 的目标基因。Megakaryoblastic 白血病 1 (MKL1,也命名的 MRTF -- 一) 并且 p300 能 synergistically 扩充 COMT 基因的表示,增加雌激素的新陈代谢的率,并且因此减少雌激素刺激的 MCF-7 乳癌房间的增长。 | Zhipeng Liu Xuegang Luo Lei Liu Wenwen Zhao Shu Guo Yu Guo Nan Wang Hongpeng He XinghuaLiao Wenjian Ma Hao Zhou Tongcun Zhang | 2013 | Acta Biochimica et Biophysica Sinica2013，45，12： | 1 |
| 4 | Reactivity and kinetic analysis of biomass during combustion显示文摘 | Wang Qing Zhao Weizhen Liu Hongpeng | 2012 | Energy Procedia2012，，： | 1 |
| 5 | Immunomodulatory and anticancer activities of phenolics from emblica fruit ( Phyllanthus emblica L.)显示文摘 | Xiaoli Liu Mouming Zhao Kegang Wu Xianghua Chai Hongpeng Yu Zhihua Tao Jinshui Wang | 2011 | Food Chemistry2011，，2： | 1 |
| 6 | Interac- tions and kinetic analysis of oil shale semi-coke with cornstalk during co-eombus tion 显示文摘 | Qing Wang Weizhen Zhao Hongpeng Liu | 2011 | Applied Energy2011，，6： | 1 |
| 7 | Interactions and kinetic analysis of oil shale semi-coke with cornstalk during co-combustion显示文摘 | Wang Qing Zhao Weizhen Liu Hongpeng | 2011 | Applied Energy2011，88，4： | 1 |
| 8 | Reactivity and kinetic analysis of biomass during combustion显示文摘 | Qing Wang Weizhen Zhao Hongpeng Liu | 2012 | Energy Procedia2012，17，： | 1 |
| 9 | A spike-trimer protein-based tetravalent COVID-19 vaccine elicits enhanced breadth of neutralization against SARS-CoV-2 Omicron subvariants and other variants显示文摘Multivalent vaccines combining crucial mutations from phylogenetically divergent variants could be an effective approach to defend against existing and future SARS-Co V-2 variants.In this study,we developed a tetravalent COVID-19 vaccine SCTV01E,based on the trimeric Spike protein of SARS-Co V-2 variants Alpha,Beta,Delta,and Omicron BA.1,with a squalenebased oil-in-water adjuvant SCT-VA02B.In the immunogenicity studies in na?ve BALB/c and C57BL/6J mice,SCTV01E exhibited the most favorable immunogenic characteristics to induce balanced and broad-spectrum neutralizing potencies against pre-Omicron variants(D614G,Alpha,Beta,and Delta)and newly emerging Omicron subvariants(BA.1,BA.1.1,BA.2,BA.3,and BA.4/5).Booster studies in C57BL/6J mice previously immunized with D614G monovalent vaccine demonstrated superior neutralizing capacities of SCTV01E against Omicron subvariants,compared with the D614G booster regimen.Furthermore,SCTV01E vaccination elicited na?ve and central memory T cell responses to SARS-Co V-2 ancestral strain and Omicron spike peptides.Together,our comprehensive immunogenicity evaluation results indicate that SCTV01E could become an important COVID-19 vaccine platform to combat surging infections caused by the highly immune evasive BA.4/5 variants.SCTV01E is currently being studied in a head-to-head immunogenicity comparison phase 3 clinical study with inactivated and m RNA vaccines(NCT05323461). | Rui Wang Hongpeng Huang Chulin Yu Chunyun Sun Juan Ma Desheng Kong Yalong Lin Dandan Zhao Shaozheng Zhou Jianbo Lu Sai Cao Yanjing Zhang Chunxia Luo Xuefeng Li Yang Wang Liangzhi Xie | 2023 | Science China(Life Sciences)2023，66，8： | 1 |
| 10 | Interactions and kinetic analysis of oil shale semi-coke with cornstalk during co-combustion显示文摘 | Qing w Weizhen Zhao Hongpeng L | 2011 | Applied Energy2011，88，6： | 1 |
| 11 | A SNOW-BLANKETED CAPITAL显示文摘Beijing boasts distinctively beautiful views inall four seasons In winter,snow is certainly a charming feature for residents and visitors in the city.In Chinese tradition,snow has long been a symbol of good harvest in the coming year,so the Chinese people naturally consider snow to be an auspicious sign.With a layer of snow covering the city,Beijing resembles a large and beautiful Chinese ink wash painting.The slivery landscape is dotted with the red walls of the Forbidden City,green pine needles and cypress leaves in parks and along roads,and yellow roofs of palatial buildings scattered throughout. | Zhang Hongpeng Ren Xingli(Photos) Yan Weiyou(Photos) Yuan Baolin(Photos) Zhao Shucheng(Photos) Zheng Qingxiang(Photos) Zhou Jin(Photos) Zhou Shijie(Photos) | 2021 | Beijing2021，，2： | 0 |
| 12 | REVITALISING OLD BEIJING显示文摘 | Zhang Hongpeng Brad Green Jin Jjianhui Sang Yi Xu Xiaoping Zhang Qi Zhao Yue | 2021 | Beijing2021，，40： | 0 |
| 13 | Association of self-reported health with alcohol consumption: a study conducted among Chinese and Canadian middle-aged and older adults显示文摘There has been lack of studies that examine the relationship between self-rated health(SRH)and alcohol consumption,particularly in middle-aged and older adult populations.This study aims to investigate association of SRH status with alcohol consumption in middle-aged and older adult populations.The study is a cross-sec-tional study design that was based on the China Health and Retired Longitudinal study(CHARLS)and the Canadian Alcohol and Drug Monitoring Survey(CAD-UMS)and the Canadian Alcohol,Tobacco and Drug Survey(CTADS).Measure of health is SRH status and self-reported alcohol use.Multinomial logistic regres-sion was performed to model the data and the odds ratio of self-reported excel-lent,very good,good and fair(versus poor)for current and former drinkers versus nondrinkers and current drinkers versus former drinkers was estimated in models after adjusting for covariates.This study found that in both Chinese and Canadian adult populations,current drinkers reported better health status than former drink-ers;lifetime nondrinkers reported better health status than former drinkers.Current drinkers reported better health status than nondrinkers.Canadian moderate drinkers(1.3-44 g per day)tended to report better health compared with occasional drinkers and Chinese heavy drinkers(45+grams per day)reported better health status com-pared with occasional drinkers in both populations.This study found current drink-ers tended to have better health status than former drinker and lifetime nondrinkers in adult populations.Nondrinkers tended to report better health status than former drinkers.Low and medium drinkers reported better health status. | Jinhui Zhao Hongpeng Sun Yana Ma Xingxue Cheng | 2020 | China Population and Development Studies2020，4，4： | 0 |
| 14 | Parameter optimization and experiment of the negative pressure precision seed-metering device for wheat显示文摘In order to ensure the most reasonable distribution of wheat seeds in the field to improve seeding quality and uniformity,a set of negative pressure precision seed-metering device was designed,which shares a hollow shaft.Every seed-metering device can sow two rows of wheat.By the STAR-CCM+,the analysis of nephogram,vectogram and streamline graph showed that more ideal structural parameters of the seed-metering device are 0.5 mm width of the slit sucking seed(WSS),150-200 mm diameter of the seed-metering disc(DSD),2.0 mm axial depth of air chamber in the seed-metering disc(ADS),and arc-shaped cross-section shape of the ring groove sucking seed(CSGS).Single-factor test on the JPS-12 test-bed analyzed the influence of the CSGS,WSS,DSD,and ADS on the qualified index(Iq),multiple index(Imul),miss index(Imiss)and coefficient of variation of qualified seed spacing(CV).Through the orthogonal on the JPS-12 test-bed,it is found that the influence of vacuum negative pressure and seed-metering device shaft speed is significant on the Iq,Imiss and Imul.Based on these,the structural parameters of the seed-metering device were optimized.The DSD is 180 mm,the WSS is 0.7 mm,the ADS is 2.5 mm,and the CSGS is arc-shaped.The optimization seed-metering device was tested on the JPS-12 test-bed.The Iq is 86.66%,the Imiss is 5.09%,the Imul is 8.25%,and the CV is 24.50%.These testing results fully coincide with the standard JB/T 10293-2013 Specifications of single seed drill(precision drill).The seed-metering device meets fully the requirements for wheat precision seeding. | Yubo Feng Xiaoshun Zhao Jincai Li Huali Yu Hongpeng Zhao Baozhong Yin | 2024 | International Journal of Agricultural and Biological Engineering2024，17，1： | 0 |
| 15 | Robust H_(∞) Control of Switched Nonlinear Systems Under Sampled Data显示文摘This paper investigates the globally asymptotically stable and L_(2)-gain of robust H_(∞)control for switched nonlinear systems under sampled data.By considering the relationship between the sampling period and the dwell time,the non-switching and one switching are discussed in the sampling interval,respectively.Firstly,a state feedback sampled-data controller is constructed by the back-stepping method,and the switching converts to asynchronous switching if it happens within the sampling interval.Then,under the limiting conditions of the sampling period,which are obtained by the average dwell time method,the closed-loop system is globally asymptotically stable and has L_(2)-gain.Finally,two numerical examples are provided to demonstrate the effectiveness of the proposed method. | ZHAO Hongpeng WANG Xingtao | 2022 | Journal of Systems Science & Complexity2022，35，5： | 0 |
| 16 | 透射电子显微镜研究低能高剂量氦离子辐照引起非晶6H-SiC微观结构演化过程显示文摘Silicon carbide(SiC)is regarded as an important material in nuclear energy system and semiconductor industry,because of its excellent physical,electronic and optical properties.It is inevitable that dense atomic He atoms produced by(n,)nuclear transmutation reaction.Due to the low solubility of He atoms in SiC,He atoms are easy to be trapped by vacancies to form helium-vacancy clusters.After thermal annealing,helium atoms will escape from vacancies,to form cavities.In semiconductor technology,He implantation-induced cavities have lots of important applications.Therefore,the study of He-implanted SiC is critical.He-implantation-induced cavities have been extensively investigated.He-implantation-induced dislocation loops also have been investigated.Chen et al.observed interstitial-type dislocation loops associated with He bubbles due to the release of bubble interior pressure via emitting interstitials[1].These interstitials agglomerate into dislocation loops.It is consistent with previous results observed in the case of He-implanted 6H-SiC[2].What’s more,Barbot et al.regarded that the growth of the Frank loops lead to the formation of stacking faults,which do not result from the agglomeration of interstitials[3]. | Li Bingsheng Han Yi Wang Zhiguang Wei Kongfang Shen Tielong Sun Jianrong Yao Cunfeng Gao Ning Gao Xing Pang Lilong Zhu Yabin Chang Hailong Cui Minghuan Luo Peng Sheng Yanbin Zhang Hongpeng Fang Xuesong Zhao Sixiang Jin Jin Huang Yuxuan Liu Chao Tai Pengfei Wang Dong He Wenhao Qi Ming | 2017 | IMP & HIRFL Annual Report2017，，1： | 0 |
| 17 | Effects of Different Shading Treatments on Agronomic Characters of Cultivated Ginseng(Panax ginseng)in Farmland显示文摘As the main environmental factor of ginseng growth,illumination plays an important role in ginseng( Panax ginseng) growth and development. Although ginseng is a shade-demanding plant,we need to get higher yield and quality under ideal light conditions. Three different illumination conditions for growth were created through different shading treatments. It was concluded that the adjustment of illumination according to monthly irradiance is beneficial to ginseng growth; appropriate illumination significantly affected root diameter; and SPAD value could also be used in the production of ginseng,but different light environments have influences on its accuracy. Reasonable light adjustment could improve the accuracy of the prediction value of SPAD. | Hongpeng LI Yingjiao LI Yuting ZHAO Xiangguo LI | 2018 | Agricultural Biotechnology2018，7，2： | 0 |
| 18 | 4-1 Lattice Disorder Produced in GaN by He-ion Implantation显示文摘Because of excellent electronic and optical properties,GaN has been used in the laser diodes,microwave,ultrahigh power switches and other fields.Due to an attractive process for selective region doping of semiconductor devices,ion implantation has widely been applied to GaN fabrication processing.However,ion implantation introduces extensive damage that can degrade the performance,properties as well as lifetimes of the devices.Thus,it is very important to understand the ion-beam damage processes in the fabrication of GaN-based devices.The effects of ion implantation into GaN have been extensively investigated. | Li Bingsheng Han Yi Wang Zhiguang Wei Kongfang Shen Tielong Sun Jianrong Yao Cunfeng Gao Ning Gao Xing Pang Lilong Zhu Yabin Chang Hailong Cui Minghuan Luo Peng Sheng Yanbin Zhang Hongpeng Fang Xuesong Zhao Sixiang Jin Jin Huang Yuxuan Liu Chao Tai Pengfei Wang Dong He Wenhao Qi Ming | 2016 | IMP & HIRFL Annual Report2016，，1： | 0 |
| 19 | Drinking alcohol increased the possibility of self-rated poor health and mortality risk among middle-aged and seniors: a longitudinal study conducted in China显示文摘There has been lack of studies that investigate the causal impact of alcohol consumption on health and mortality in middle-aged and older populations in China.This cohort study aims to investigate whether alcohol use increases poor health and mortality risk in middle-aged and older Chinese population.The study is a cohort study design that was based on the China Health and Retired Longitudinal study(CHARLS).Measures of poor health and alcohol use are self-rated poor/very poor and alcohol use.Competing Cox proportional hazard regression model(CPHM)was used to model the data and the hazards ratio(HR)of poor health,mortality for current and former drinkers versus nondrinkers and current drinkers versus former drinkers was estimated using CPHM after adjusting for deign-effects and covariates.This study found significantly increased risk of all-cause mortality among current(adjusted HR=1.54 and P=0.0423)and former drinkers(Adjusted HR=1.52 and P=0.0096)compared to lifetime nondrinkers among middle-aged and senior Chinese people;significantly increased hazard of poor health among current drinkers(Adjusted HR=1.26 and P=0.0443)compared with lifetime nondrinkers.The hazards of all-cause mortality and self-rated poor health increased with the amount and frequency of alcohol drinking,and drinking years.This study found that either former or current drinkers self-rated having a poor health and had a significantly increased risk of all-cause mortality compared with nondrinkers.Heavy drinkers had poor health status and higher risk of mortality compared with those who drank light or moderate amount of alcohol in middle-aged and senior Chinese population. | Jinhui Zhao Yana Ma Hongpeng Sun | 2021 | China Population and Development Studies2021，5，5： | 0 |
| 20 | Effect of annealing treatment on the performance of organic photovoltaic devices using SPFGraphene as electron-accepter material显示文摘We have researched the performances of organic photovoltaic devices with the bulk heterojunction (BHJ) structure using the organic solution-processable functionalized graphene (SPFGraphene) material as the electron-accepter material and P3OT as the donor material. The structural configuration of the device is ITO/PEDOT:PSS/P3OT:PCBM-SPFGraphene/LiF/Al. Given the P3OT/PCBM (1:1) mixture with 8wt% of SPFGraphene, the open-circuit voltage (Voc) of the device reaches 0.64 V, a short-circuit current density (Jsc) reaches 5.7 mA/cm2, a fill factor (FF) reaches 0.42, and the power conversion efficiency ( ) reaches 1.53% at illumination at 100 mW/cm2 AM1.5. We further studied the reason for the device performances improvement. In the P3OT:PCBM-SPFGraphene composite, the SPFGraphene material acts as exciton dissociation sites and provides the transport pathways of the lowest unoccupied molecular orbital (LUMO)-SPFGraphene-Al. Furthermore, adding SPFGraphene to P3OT results in appropriate energetic distance between the highest occupied molecular orbital (HOMO) and LUMO of the donor/acceptor and provides higher exciton dissociation volume mobility of carrier transport. We have researched the effect of annealing treatment for the devices and found that the devices with annealing treatment at 180°C show better performances compared with devices without annealed treatment. The devices with annealed treatment show the best performance, with an enhancement of the power conversion efficiency from 1.53% to 1.75%. | WANG HaiTeng HE DaWei WANG YongSheng LIU ZhiYong WU HongPeng WANG JiGang ZHAO Yu | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，8： | 0 |
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