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| 1 | The application of large volume airgun sources to the onshore-offshore seismic surveys: implication of the experimental results in northern South China Sea显示文摘Onshore-offshore seismic experiments were carried out for the first time in northern South China Sea using large volume airgun sources at sea and seismic stations on land. The experimental results indicate that seismic signals from the new airgun array of R/V Shiyan 2 can be detected as far as 255 km. The signal effective area reaches nearly 50000 km2, which covers Hong Kong and Pearl River Delta. Compared with the old airgun array, the signal amplitude, propagation distance and effective area of the new airgun array have been increased notably, which demonstrates that the upgrade of the airgun source was successful. Comparisons with previous experimental results in other regions show that the shooting effect of the new airgun array is similar to those best airgun sources in the world. Especially, it is a new breakthrough in using the permanent seismic stations onshore to record long distance airgun signals offshore, which has great significance to the realization of the 'seismic radar' concept and the 3D seismic surveys of crustal structure in coastal areas. | QIU XueLin CHEN Yong ZHU RiXiang XU HuiLong SHI XiaoBin YE ChunMing ZHAO MingHui XIA ShaoHong | 2007 | Chinese Science Bulletin2007，52，4： | 27 |
| 2 | The South China Sea is not a mini-Atlantic: plate-edge rifting vs intra-plate rifting显示文摘The South China Sea,as‘a non-volcanic passive margin basin’in the Pacific,has often been considered as a small-scale analogue of the Atlantic.The recent ocean drilling in the northern South China Sea margin found,however,that the Iberian model of non-volcanic rifted margin from the Atlantic does not apply to the South China Sea.In this paper,we review a variety of rifted basins and propose to discriminate two types of rifting basins:plate-edge type such as the South China Sea and intra-plate type like the Atlantic.They not only differ from each other in structure,formation process,lifespan and geographic size,but also occur at different stages of the Wilson cycle.The intra-plate rifting occurred in the Mesozoic and gave rise to large oceans,whereas the plate-edge rifting took place mainly in the mid-Cenozoic,with three-quarters of the basins concentrated in the Western Pacific.As a member of the Western Pacific system of marginal seas,the South China Sea should be studied not in isolation on its origin and evolution,but in a systematic context to include also its neighboring counterparts. | Pinxian Wang Chi-Yue Huang Jian Lin Zhimin Jian Zhen Sun Minghui Zhao | 2019 | National Science Review2019，6，5： | 24 |
| 3 | Temporo-spatial Coordinates of Evolution of the Ordos Basin and Its Mineralization Responses显示文摘摘要:Ordos 盆被开发从中间迟了对早白垩纪三叠纪,然后自从迟了的白垩纪,进入了它的以后的改革时期。它的主要身体忍受 intra-cratonic 盆的特征。盆也属于在大规模盆上重叠了的多迭加的盆早并且晚古生代。当前, Ordos 盆成为了剩余盆各种各样的式样的富有经验的改革自从迟了的白垩纪。它建议了有在盆的进化期间存在的构造变丑的至少四个明显的阶段,把进化和沉积划分成四个阶段。优先二个阶段具有最繁荣,在哪个期间湖盆是宽广的,免职范围多于比当前的剩余盆两次大,导致主要含有石油、忍受煤的阶层。二个阶段被分开由地区性高举在区域的变化。在 Yan'an 阶段的结束, depositional 打断和侵蚀正在持续时间的一个短时期。第三是中间 -- 侏罗记并且 Zhiluo 舞台,沉积程度仍然在是宽广的但是湖区域显然被减少。在迟了的侏罗记构造变丑是集中的。当不同厚度的集团企业在东方方面的 foredeep 以内被积累时,一条戳越过水坝落下的水带在盆的西方的边缘上被形成。盆的中央、东方的部分服从于侵蚀和改革。一个地区性的框架与在西方在东方和消沉高举黄河向西在区域形成了。在早白垩纪,沉积广泛地被散布, unconformably 重叠北、南部的边阶上的以前的西方的边缘戳带和山脉。象在 Ordos 盆形成的油,天然气,煤和铀存款那样有丰富的精力资源。产生的主要阶段,矿化作用并且资源有明显的反应的多重精力放在 Ordos 中生代和新生代进化和改革与那些联合关系的连接和结束盆。 | LIU Chiyang ZHAO Hongge ZHAO Junfeng WANG Jianqiang ZHANG Dongdong YANG Minghui | 2008 | Acta Geologica Sinica(English Edition)2008，82，6： | 20 |
| 4 | Characteristics of the crustal structure and hypocentral tectonics in the epicentral area of Nan'ao earthquake (M7.5), the northeastern South China Sea显示文摘1918 Nan’ao earthquake (M7.5) occurred in the northeast coastal areas of Guangdong Province. With the seismogeological survey of the epicentral area and history materials analyses, the earthquake epicenter was estimated to locate in the intersection part of the Binhai fault zone (Littoral) and Huanggangshui fault, which strikes NEE and NW, respectively. The activities of the NEE-striking thrust fault and NW-striking extensional fault that were attributed to 1918 Nan’ao earthquake occurred in the Dongshan Island of the epicentral area; they reflected the focal stress field with compression in NW-SE direction and extension in NE-SW direction. The isoseismal contour of seismic intensity X shows a shape of ‘X’ composed of two mutually overlapping ellipses with two axes striking NEE and NW, respectively, and such shape implies that the occurrence of this earthquake is controlled by a pair of conjugate seismotectonic faults constituted by the NEE-striking Binhai fault zone and the NW-striking Huanggangshui fault. The Binhai fault zone is a dominant seismogenic structure, and the NW-striking Huanggangshui fault is the subdominant one. The onshoreoffshore deep seismic profile that crossed the epicentral area and was perpendicular to the strike of the Binhai fault zone was obtained. According to the analyses of the seismic data, the Binhai fault zone is defined as a low velocity zone with SE dip-slip in thecrustal structure section. The Binhai fault zone is a boundary fault between the South China subplate and South China Sea subplate. The crust structure on the northwest side of Binhai fault zone is a normal continental crust with a thickness of 30 km, and the one on the southeast side of the fault zone is a thinning continental crust with a thickness of 25―28 km. The Binhai fault zone is an important seismogenic fault and also is an earthquake-controlling fault. The intersection part between the Binhai fault zone and the low velocity zone of upper crust is advantageous to stress concentration and strain energy accumulation, and presents the deep dynamic conditions for the earthquake’s pregnancy and occurrence. | XU Huilong QIU Xuelin ZHAO Minghui SUN Jinlong ZHU Junjiang | 2006 | Chinese Science Bulletin2006，51，B12： | 17 |
| 5 | Early Serum HBsAg Kinetics as Predictor of HBsAg Loss in Patients with HBeAg-Negative Chronic Hepatitis B after Treatment with Pegylated Interferonα-2a显示文摘Hepatitis B surface antigen(HBsAg)loss is an ideal treatment endpoint for patients with chronic hepatitis B(CHB).We investigated the predictive value of on-treatment HBsAg levels for HBsAg loss in hepatitis B e antigen(HBe Ag)-negative CHB patients who received 120-week PEG-IFNα-2a treatment.Serum HBV DNA,HBsAg,and anti-HBs levels were assayed at baseline and every 3 months during the treatment.Of 81 patients,12 achieved HBsAg loss,20 achieved HBsAg\100 IU/mL,and 49 maintained HBs Ag C 100 IU/mL.HBsAg loss rate was only 3.7%at 48 weeks,while it reached to 11.1%and 14.8%after treatment of 96 weeks and 120 weeks.The cutoff HBs Ag levels at 12 weeks predicting HBsAg loss at 96 weeks and 120 weeks of treatment were 400 IU/mL and 750 IU/mL,with AUC 0.725 and 0.722,positive predictive value(PPV)29.41%and 30.56%,and negative predictive value(NPV)93.75%and 97.78%,respectively.The cutoff HBsAg levels at 24 weeks predicting HBsAg loss at 96 weeks and 120 weeks of treatment were 174 IU/m L and 236 IU/mL respectively,with AUC 0.925 and 0.922,PPV 40.0%and 46.15%,and both NPV 100%.The predictive ability of the cutoff HBsAg levels at 24 weeks was better than that at 12 weeks for HBs Ag loss at either 96 or 120 weeks(χ~2=3.880,P=0.049 andχ~2=4.412,P=0.036).These results indicate that extended therapy is critical to HBsAg loss in HBe Ag-negative CHB patients during PEG-IFN treatment,and the HBsAg level at 24 weeks can be used to predict HBsAg loss during tailoring PEG-IFN therapy. | Minghui Li Lu Zhang Yao Lu Qiqi Chen Huihui Lu Fangfang Sun Zhan Zeng Gang Wan Linqing Zhao Yao Xie | 2021 | Virologica Sinica2021，36，2： | 15 |
| 6 | miR-181b functions as an oncomiR in colorectal cancer by targeting PDCDZ显示文摘 | Yanqing Liu Uzair-ur-Rehman Yu Guo Hongwei Liang Rongjie Cheng Fei Yang Yeting Hong Chihao Zhao Minghui Liu Mengchao Yu Xinyan Zhou Kai Yin Jiangning Chen Junfeng Zhang Chen-Yu Zhang Feng Zhi Xi Chen | 2016 | Protein & Cell2016，7，10： | 14 |
| 7 | Directional sliding of water:biomimetic snake scale surfaces显示文摘Bioinspired superhydrophobic surfaces have attracted many industrial and academic interests in recent years.Inspired by unique superhydrophobicity and anisotropic friction properties of snake scale surfaces,this study explores the feasibility to produce a bionic superhydrophobic stainless steel surface via laser precision engineering,which allows the realization of directional superhydrophobicity and dynamic control of its water transportation.Dynamic mechanism of water sliding on hierarchical snake scale structures is studied,which is the key to reproduce artificially bioinspired multifunctional materials with great potentials to be used for water harvesting,droplet manipulation,pipeline transportation,and vehicle acceleration. | Yizhe Zhao Yilin Su Xuyan Hou Minghui Hong | 2021 | Opto-Electronic Advances2021，4，4： | 12 |
| 8 | Genetic and biological characteristics of the globally circulating H5N8 avian influenza viruses and the protective efficacy offered by the poultry vaccine currently used in China显示文摘The H5N8 avian influenza viruses have been widely circulating in wild birds and are responsible for the loss of over 33 million domestic poultry in Europe, Russia, Middle East, and Asia since January 2020. To monitor the invasion and spread of the H5N8 virus in China, we performed active surveillance by analyzing 317 wild bird samples and swab samples collected from 41,172 poultry all over the country. We isolated 22 H5N8 viruses from wild birds and 14 H5N8 viruses from waterfowls. Genetic analysis indicated that the 36 viruses formed two different genotypes: one genotype viruses were widely detected from different wild birds and domestic waterfowls;the other genotype was isolated from a whopper swan. We further revealed the origin and spatiotemporal spread of these two distinct H5N8 virus genotypes in 2020 and 2021. Animal studies indicated that the H5N8 isolates are highly pathogenic to chickens, mildly pathogenic in ducks, but have distinct pathotypes in mice. Moreover, we found that vaccinated poultry in China could be completely protected against H5N8 virus challenge. Given that the H5N8 viruses are likely to continue to spread in wild birds, vaccination of poultry is highly recommended in high-risk countries to prevent H5N8 avian influenza. | Pengfei Cui Xianying Zeng Xuyong Li Yanbing Li Jianzhong Shi Conghui Zhao Zhiyuan Qu Yanwen Wang Jing Guo Wenli Gu Qi Ma Yuancheng Zhang Weipeng Lin Minghui Li Jingman Tian Dongxue Wang Xin Xing Yanjing Liu Shuxin Pan Yaping Zhang Hongmei Bao Liling Liu Guobin Tian Chengjun Li Guohua Deng Hualan Chen | 2022 | Science China(Life Sciences)2022，65，4： | 12 |
| 9 | Using borehole core analysis to reveal Late Quaternary paleoearthquakes along the Nankou-Sunhe Fault,Beijing显示文摘The Nankou-Sunhe Fault is a buried active normal fault that traverses the urban area of Beijing.Its seismic risks have caused considerable concerns.This paper studies paleoearthquakes along this fault by analyzing and correlating bore-hole cores obtained from triple-tube coring,incorporating experience acquired from trenching.As a result,a model for identifying earthquake-derived colluvium by sediment-core analysis is proposed.Triple-tube coring technique is useful to collect continuous undis-turbed soil core near the Nankou-Sunhe Fault.By identifying fault-scarp colluviums,determining cumulative displacement,and analysing stratum thickening on the hanging wall,we are able to establish a preliminary paleoearthquake sequence consisting of 13 surface-rupturing events since 60 ka.The seismic history can be divided into three periods based on different recurrence intervals.Between 60 and 40 ka,three earthquakes occurred with recurrence interval of ~10 ka.From 40 to 25 ka,there were six earthquakes with the recurrence interval of about 2.5 ka.In the last 25 ka,four earthquakes have taken place with the recurrence interval varying considerably.The recurrence interval between the last three events is ~5 ka.Smaller recurrence intervals correspond to stages of faster fault slip.The coseismic displacement of a single event is 0.8 to 2.2 m,average 1.4 m,largely equivalent to moment magnitudes 6.7-7.1.This study demonstrates the feasibility of bore-hole drilling in investigating paleoearthquakes along normal faults.It also suggests that closely spaced boreholes with continuous undisturbed cores are essential for reconstructing the complete paleoearthquake sequence. | ZHANG ShiMin WANG DanDan LIU XuDong ZHANG GuoHong ZHAO JunXiang LUO MingHui REN JunJie WANG Rui ZHANG YingLi | 2008 | Science China Earth Sciences2008，51，8： | 11 |
| 10 | Population Genomic Analysis and De Novo Assembly Reveal the Origin of Weedy Rice as an Evolutionary Game显示文摘Crop weediness,especially that of weedy rice(Oryza sativa f.spontanea),remains mysterious.Weedy rice possesses robust ecological adaptability;however,how this strain originated and gradually formed proprietary genetic features remains unclear?Here,we demonstrate that weedy rice at Asian high latitudes(WRAH)is phylogenetically well defined and possesses unselected genomic characteristics in many divergence regions between weedy and cultivated rice.We also identified novel quantitative trait loci underlying weedy-specific traits,and revealed that a genome block on the end of chromosome 1 is associated with rice weediness.To identify the genomic modifications underlying weedy rice evolution,we generated the first de novo assembly of a high-quality weedy rice genome(WR04-6),and conducted a comparative genomics study between WR04-6 with other rice reference genomes.Multiple lines of evidence,including the results of demographic scenario comparisons,suggest that differentiation between weedy rice and cultivated rice was initiated by genetic improvement of cultivated rice and that the essence of weediness arose through semi-domestication.A plant height model further implied that the origin of WRAH can be modeled as an evolutionary game and indicated that strategy-based selection driven by fitness shaped its genomic diversity. | Jian Sun Dianrong Ma Liang Tang Minghui Zhao Guangchen Zhangh Wenjia Wang Jiayu Song Xiang Li Zimeng Liu Wenxing Zhang Quan Xu Yuncheng Zhou Jianzhong Wu Toshio Yamamoto Fei Dai Yan Lei Song Li Gang Zhou Hongkun Zheng Zhengjin Xu Wenfu Chen | 2019 | Molecular Plant2019，12，5： | 9 |
| 11 | OCEAN BOTTOM SEISMOMETER AND ONSHOREOFFSHORE SEISMIC EXPERIMENT IN NORTHEASTERN SOUTH CHINA SEA显示文摘Three-component Ocean Bottom Seismometers, portable land stations and marine air gun seismic sources were used to carry out an onshore-offshore deep seismic profile in northeastern South China Sea. This profile, orientated in NNW-SSE, was as long as 500 km and perpendicular to the strike of regional tectonics. The offshore data were processed in Taiwan Ocean University using a number of available software and the onshore data were analyzed in South China Sea Institute of Oceanology by new-written programs and public software. Preliminary results show that the seismic data are in good quality and contain rich information of deep structure. Seismic phases, e.g. Pg, PmP and Pn, are identified in the offset range 5~220 kin, which will provide an important dataset for the deep crustal structure and oil-gas basin evolution studies of this region. | QIU Xuelin ZHAO Minghui YE Chunming WANG Tankai WANG Ping ZHANG Yixiang XIA Kanyuan LEE Chaoshing | 2004 | Geotectonica et Metallogenia2004，28，1： | 8 |
| 12 | Finite element modeling of pore-fluid flow in the Dachang ore district,Guangxi,China:Implications for hydrothermal mineralization显示文摘当温度坡度足够地高时,在地球的上面的外壳以内在多孔的岩石和破裂中与毛孔液体的发行量联系的对流的热转移是实质的。以便在 Guangxi 的 Dachang 矿石区域理解 Sn-polymetallic 矿化作用的过程,一个有限元素方法在这研究被使用了在这个区域模仿毛孔液体流动和热转移。根据相关地质、构造、地球物理的限制,一个计算模型被建立。它使计算模拟和敏感分析能为调查可以在这个区域影响热水的矿石开始的形成矿石的毛孔液体流动和其它钥匙因素被执行。相关模拟结果显示了那:(1 ) 在矿石区域能为毛孔液体作为优先的小径服务的 Dachang 的可渗透的差错地区流动在上一地区性规模;并且(2 ) 毛孔液体流动能影响咸度分发。这个后者因素是 Sn-polymetallic 矿化作用发生在这个区域的原因的部分。 | Minghui Ju Chongbin Zhao Tagen Dai Jianwen Yang | 2011 | Geoscience Frontiers2011，2，3： | 8 |
| 13 | TWISTED DWARF 1 Associates with BRASSINOSTEROID-INSENSITIVE 1 to Regulate Early Events of the Brassinosteroid Signaling Pathway显示文摘为异种证明改变的 brassinosteroid (BR ) 敏感或象 bri1 一样显型导致了扭曲的矮子 1 的二新变异的等位基因(TWD1 ) 的鉴定的一幅染色体宽的屏幕, twd1-4,和 twd1-5。以前的研究显示了那 TWD1,也作为 ULTRACURVATA 2 或 FKBP42 说出,与植物生长素流出 transporters 联系并且为他们的生物功能是必要的。尽管更早的报告证明 BR 发信号是在 twd1 的 downregulated, TWD1 怎么集成于 BR 发信号,没被阐明。这里,我们提供证明 TWD1 以一种 BR 独立的方式与 BR 受体 BRI1 invivo 交往的基因、生物化学的证据。进一步的分析显示 TWD1 不由改变调制 BR 信号 transduction 嗯质量控制或蛋白质许多 BRI1;相反, TWD1 看起来在 BRI1 和它的合作受体的导致 BR 的相互作用批评这二蛋白质的 BAK1,以及导致 BR 的 phosphorylation。这些结果提供表明小径的 BR 的早事件的更好的理解。 | Baolin Zhao Minghui Lv Zengxiu Feng Thomas Campbell Emmanuel Liscum Jia Li | 2016 | Molecular Plant2016，9，4： | 8 |
| 14 | Crustal S-wave velocity structure across the northeastern South China Sea continental margin: implications for lithology and mantle exhumation显示文摘The northeastern margin of the South China Sea (SCS), developed from continental rifting and breakup, is usually thought of as a non-volcanic margin. However, post-spreading volcanism is massive and lower crustal high-velocity anomalies are widespread, which complicate the nature of the margin here. To better understand crustal seismic velocities, lithology, and geophysical properties, we present an S-wave velocity (VS) model and a VP/VS model for the northeastern margin by using an existing P-wave velocity (VP) model as the starting model for 2-D kinematic S-wave forward ray tracing. The Mesozoic sedimentary sequence has lower VP/VS ratios than the Cenozoic sequence;in between is a main interface of P-S conversion. Two isolated high-velocity zones (HVZ) are found in the lower crust of the continental slope, showing S-wave velocities of 4.0–4.2 km/s and VP/VS ratios of 1.73–1.78. These values indicate a mafic composition, most likely of amphibolite facies. Also, a VP/VS versus VP plot indicates a magnesium-rich gabbro facies from post-spreading mantle melting at temperatures higher than normal. A third high-velocity zone (VP : 7.0–7.8 km/s;VP/VS: 1.85–1.96), 70-km wide and 4-km thick in the continent-ocean transition zone, is most likely to be a consequence of serpentinization of upwelled upper mantle. Seismic velocity structures and also gravity anomalies indicate that mantle upwelling/ serpentinization could be the most severe in the northeasternmost continent-ocean boundary of the SCS. Empirical relationships between seismic velocity and degree of serpentinization suggest that serpentinite content decreases with depth, from 43% in the lower crust to 37% into the mantle. | WenAi Hou Chun-Feng Li XiaoLi Wan MingHui Zhao XueLin Qiu | 2019 | Earth and Planetary Physics2019，3，4： | 8 |
| 15 | Effect of Zhuyeshigao granule on tumor necrosis factor-α and inter leukins serum protein levels in rats with radiation esophagitis显示文摘OBJECTIVE: To investigate the effects of Zhuyeshigao granule(ZSG) on tumor necrosis factor-α(TNF-α), interleukin-1(IL-1), IL-2, IL-6, and IL-8 in rats with radiation esophagitis.METHODS: Fifty Wistar rats were randomly divided into five groups(10 rats in each group): control(without radiation), saline-treated, and low,medium, and high-dose ISG-treated groups. Rats were given normal saline(10 mL/kg) or 1.15, 2.3,or 4.6 g/kg ZSG by intragastric administration once a day for 7 days. A rat model of radiation esophagitis was established by local irradiation of Co60(490.25 cGy/min, totaling 30 Gy). The administration of ZSG was continued for another 7 days and on the 7th day post-irradiation, inferior vena cava blood was collected.The serum was separated, and TNF-α, IL-1, IL-2, IL-6, and IL-8 protein levels were determined.RESULTS: Inflammatory response factors were found in the serum of each group. However, levels in ZSG-treated groups were significantly lower than inthesaline-treatedgroup(P<0.05).CONCLUSION: ZSG may prevent the development of radiation esophagitis, perhaps by inhibiting the generation and release of the inflammatory responsefactorsTNF-α,IL-1,IL-2,IL-6,andIL-8. | Junzhang Lu Chen Wang Xiutang Cao Minghui Yang Hong Zhao Yi Liu | 2014 | Journal of Traditional Chinese Medicine2014，34，3： | 8 |
| 16 | Molecular network-based intervention brings us closer to ending the HIV pandemic显示文摘Precise identification of HIV transmission among populations is a key step in public health responses.However,the HIV transmission network is usually difficult to determine.HIV molecular networks can be determined by phylogenetic approach,genetic distance-based approach,and a combination of both approaches.These approaches are increasingly used to identify transmission networks among populations,reconstruct the history of HIV spread,monitor the dynamics of HIV transmission,guide targeted intervention on key subpopulations,and assess the effects of interventions.Simulation and retrospective studies have demonstrated that these molecular network-based interventions are more cost-effective than random or traditional interventions.However,we still need to address several challenges to improve the practice of molecular network-guided targeting interventions to finally end the HIV epidemic.The data remain limited or difficult to obtain,and more automatic real-time tools are required.In addition,molecular and social networks must be combined,and technical parameters and ethnic issues warrant further studies. | Xiaoxu Han Bin Zhao Minghui An Ping Zhong Hong Shang | 2020 | Frontiers of Medicine2020，14，2： | 7 |
| 17 | Hydrothermal Synthesis of MoO_2 and Supported MoO_2 Catalysts for Oxidative Desulfurization of Dibenzothiophene显示文摘A novel method for obtaining spherical MoO2 nanoparticles and SiO2-Al2O3 supported MoO2 by hydrothermal reduction of Mo(VI) species was studied. The obtained MoO2 catalysts show very high catalytic activity in the oxidative desulfurization(ODS) process. The effect of hydrothermal temperature and crystallization temperature on ODS activity was investigated. The ODS activity of supported MoO2 catalysts with various MoO2 contents were also investigated. The mechanism for formation of MoO2 involving oxalic acid was proposed. | Wang Danhong Zhang Jianyong Liu Ni Zhao Xin Zhang Minghui | 2014 | China Petroleum Processing & Petrochemical Technology2014，16，4： | 7 |
| 18 | Prevalence and treatment of hypertension in China: impacts of 2017 American College of Cardiology/American Heart Association High Blood Pressure Guideline显示文摘The definition, recommended treatment thresholds and targets of hypertension have been updated in the recent 2017 American College of Cardiology/American Heart Association(ACC/AHA) Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults. However,the impacts of this guideline on Chinese population are currently unknown. In this study, we aim to provide updated data in China using criteria from the updated guideline. A multistage, stratified sampling method was used to obtain a representative sample of 50,171 adults aged 18 years and above.Hypertension was defined as an average systolic blood pressure !130 mm Hg, or an average diastolic blood pressure !80 mm Hg, or self-reported use of antihypertensive medications in past 2 weeks. The weighted prevalence of hypertension was 60.1%(95% confidence interval [CI] 59.3%–61.0%). The treatment rate and recommended treatment rate were 16.8%(95% CI 16.1%–17.6%) and 53.7%(95% CI52.6%–54.9%), respectively; the gap was more prominent among men and participants from rural areas.Hence, the adoption of the 2017 ACC/AHA guideline will lead to a substantial increase in both prevalence and number of patients needing treatment in China. The applicability of this guideline should be carefully evaluated based on evidence from Chinese population. | Chao Yang Jinwei Wang Bixia Gao Yan Zhang Fang Wang Luxia Zhang Minghui Zhao Yong Huo | 2018 | Science Bulletin2018，63，8： | 7 |
| 19 | Cycle stability of lithium/garnet/lithium cells with different intermediate layers显示文摘The garnet-type electrolytes such as Ta-doped Li_7La_3Zr_2O_(12)(LLZTO) have been viewed as the promising electrolytes for solid-state lithium batteries, but it exhibits problem of high interfacial resistance(1960 Ω·cm^2) and short circuit when being cycled in Li/LLZTO/Li cells at the current density above 0.5 mA·cm^(-2). Introduction of intermediate layers in between lithium and LLZTO is helpful for decreasing the interfacial resistance and suppressing the growth of lithium dendrites. In this work, three kinds of intermediate layers of Au, Nb and Si with the thickness of 100 nm were prepared. Although the interfacial resistance with the Au layer decreases from 1960 to 32 Ω·cm^2, the cells can only cycle for 0.67 h at 0.5 mA·cm^(-2), related to the Au peeled off from the LLZTO. The Nb layers lead to the initial interfacial resistance of 14 Ω·cm^2, while showing extension of cycle time to 50 h with the increase in interfacial resistance due to the formation of the resistive Li–Nb–O phase. The Si layers induce the interfacial resistance as low as 5 Ω·cm^2 and the cycles as long as 120 h, which is attributed to the improvement in electrical contact between Li and electrolyte as well as the maintenance of conductive interface during cycles. | Ning Zhao Rui Fang MingHui He Cheng Chen YiQiu Li ZhiJie Bi Xiang-Xin Guo | 2018 | Rare Metals2018，37，6： | 7 |
| 20 | Baicalein suppresses vasculogenic mimicry through inhibiting RhoA/ROCK expression in lung cancer A549 cell line显示文摘Vasculogenic mimicry(VM)refers to a new tubular network of the blood supply system with abundant extracellular matrix.VM is similar to capillaries but does not involve endothelial cells.As a traditional herbal medicine commonly used in China,baicalein possesses anti-inflammatory and lipoxygenase activities.However,the effects of baicalein on the process of VM formation in nonsmall cell lung cancer(NSCLC)and the underlying mechanisms have remained poorly understood.In this study,baicalein was found to inhibit the viability and motility of A549 cells and induced the breakage of the cytoskeletal actin filament network.In addition,baicalein significantly decreased the formation of VM and downregulated the expressions of VM-associated factors,such as VEcadherin,EphA2,MMP14,MMP2,MIVIP9,PI3K and LAMC2,similar to the effects of ROCK inhibitors.In deed,baicalei n inhibited RhoA/ROCK expression in vitro and in vivo,suggesting the underlying mechanisms of reduced VM formation.Collectively,baicalein suppressed the formation of VM in NSCLC by targeting the RhoA/ROCK signaling pathway,indicating that baicalein might serve as an emerging drug for NSCLC. | Zhe Zhang Li Nong Menglei Chen Xiaoli Gu Weiwei Zhao Minghui Liu Wenwu Cheng | 2020 | Acta Biochimica et Biophysica Sinica2020，52，9： | 5 |
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