|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Geochemistry of Permian Mafic Igneous Rocks from the Napo-Qinzhou Tectonic Belt in Southwest Guangxi, Southwest China: Implications for Arc-Back Arc Basin Magmatic Evolution显示文摘The Napo-Qinzhou Tectonic Belt (NQTB) lies at the junction of the Yangtze, Cathaysia and Indochina (North Vietnam) Blocks, which is composed of five major lithotectonic subunits: the Qinzhou-Fangcheng Suture Zone (QFSZ), the Shiwandashan Basin (SB), the Pingxiang-Nanning Suture Zone (PNSZ), the Damingshan Block (DB) and the Babu-Lingma Suture Zone (BLSZ). On the basis of geochemical compositions, the Permian mafic igneous rocks can be divided into three distinct groups: (1) mafic igneous rocks (Group 1) from the Longjing region in the PNSZ and Hurun region in the BLSZ, which are characterized by intermediate Ti, P and Zr with low Ni and Cr contents; (2) mafic igneous rocks (Group 2) from the Naxiao and Chongzuo region in the DB, characterized by low-intermediate Ti, P and Zr with high Ni and Cr concentrations; and (3) mafic igneous rocks (Group 3) from the Siming region in the Jingxi carbonate platform of the northwestern margin of the NQTB, with intermediate-high Ti, P and Zr and low Ni and Cr contents. The Group 1 rocks yield a weighted mean 206 Pb/ 238 U age of 250.5±2.8 Ma and are geochemically similar to basalts occurring in back-arc basin settings. The Group 2 rocks exhibit geochemical features to those basalts in island arcs, whereas the Group 3 rocks show geochemical similarity to that of ocean island basalts. All three groups are characterized by relatively low ε Nd (t) values (-2.61 to +1.10) and high initial 87 Sr/ 86 Sr isotopic ratios (0.705309-0.707434), indicating that they were derived from a subduction-modified lithospheric mantle and experienced assimilation, fractional crystallization, and crustal contamination or mixing during magmatic evolution. Accordingly, we propose the existence of an arc-back arc basin system that developed along the NQTB at the border of SW Guangxi Province (SW China) and northern Vietnam, and it was formed by continued northwestward subduction of the Cathaysian (or Yunkai) Block under the Yangtze Block, and northeastward subduction of the Indochina Block beneath the Yangtze Block during Permian time. | QIN Xiaofeng WANG Zongqi ZHANG Yingli PAN Luozhong HU Guiang ZHOU Fusheng | 2012 | Acta Geologica Sinica(English Edition)2012，86，5： | 19 |
| 2 | Suppression of m6A reader Ythdf2 promotes hematopoietic stem cell expansion显示文摘 | Zhenrui Li Pengxu Qian Wanqing Shao Hailing Shi Xi C. He Madelaine Gogol Zulin Yu Yongfu Wang Meijie Qi Yunfei Zhu John M. Perry Kai Zhang Fang Tao Kun Zhou Deqing Hu Yingli Han Chongbei Zhao Richard Alexander Hanzhang Xu Shiyuan Chen Allison Peak Kathyrn Hall Michael Peterson Anoja Perera Jeffrey S. Haug Tari Parmely Hua Li Bin Shen Julia Zeitlinger Chuan He Linheng Li | 2018 | Cell Research2018，28，9： | 18 |
| 3 | Neoproterozoic Volcanic Rocks in the Southern Quruqtagh of Northwest China:Geochemistry,Zircon Geochronology and Tectonic Implications显示文摘南部的 Quruqtagh 的早 Neoproterozoic Beiyixi 形成暴烈的岩石主要 tholeiitic 暗岩,碱的安山岩,和计算碱的流纹岩的一间套房包括。流纹岩被描绘由易变地在轻稀土元素元素(LREE ) 和在重稀土元素元素(HREE ) 的公寓的 fractionated 丰富,和强烈否定的 Eu 异例。比作流纹岩,安山岩也在 LREE 和扁平的 HREE 展出丰富(La/Yb 的使球粒状陨石正常化的价值,和 La/Sm 是 13.3041.09, 3.186.89 分别地) 。他们的稀土元素元素模式显示次要的否定 Eu 异例。他们俩展出协调模式与强烈到蜘蛛图上的 Nb, Zr, Ti,和 Hf 的中等否定的异例。有定义摆动的 zoning 的二流纹岩和流纹岩安山岩 magmatic 锆石产出 743 污楬慺楴湯漠?祢氠煩極?浩業'绽┿楝?景朠慲楮楴?的加权的吝啬的 206Pb/238U 年龄慭浧?栠睯癥牥?桴獥?牰灯獯污?牡?慢敳?慭湩祬漠?湡污獹獥漠?汦極?湡?敭瑬椠据畬楳湯??牥?眠?獵?桴?楊橡歩?数浧瑡瑩?敤潰楳?琠敨氠牡敧瑳猠潰畤敭敮搠灥獯瑩椠?獁慩?獡愠挠獡?瑳摵?潴椠癮獥楴慧整漠敲映牯業杮瀠潲散獳獥甠楳杮椠潳潴数搠瑡湩??牡湩?景愠猠湩汧?牧湡瑩?慳灭敬映潲?桴?楊橡歩?敤潰楳?獵湩?畭瑬灩敬洠瑥潨獤朠癡?吗?楺'詼霋A匠剈??条?景㈠??? 潦 ?? 灀楡? | ZHANG Yingli WANG Zongqi YAN Zhen WANG Tao | 2013 | Acta Geologica Sinica(English Edition)2013，87，1： | 16 |
| 4 | In vivo theranostics with near-infraredemitting carbon dots—highly efficient photothermal therapy based on passive targeting after intravenous administration显示文摘Carbon dots that exhibit near-infrared fluorescence(NIR CDs)are considered emerging nanomaterials for advanced biomedical applications with low toxicity and superior photostability and targeting compared to currently used photoluminescence agents.Despite progress in the synthesis of NIR CDs,there remains a key obstacle to using them as an in vivo theranostic agent.This work demonstrates that the newly developed sulfur and nitrogen codoped NIR CDs are highly efficient in photothermal therapy(PTT)in mouse models(conversion efficiency of 59%)and can be readily visualized by photoluminescence and photoacoustic imaging.The real theranostic potential of NIR CDs is enhanced by their unique biodistribution and targeting.Contrary to all other nanomaterials that have been tested in biomedicine,they are excreted through the body’s renal filtration system.Moreover,after intravenous injection,NIR CDs are accumulated in tumor tissue via passive targeting,without any active species such as antibodies.Due to their accumulation in tumor tissue without the need for intratumor injection,high photothermal conversion,excellent optical and photoacoustic imaging performance,and renal excretion,the developed CDs are suitable for transfer to clinical biomedical practice. | Xin Bao Ye Yuan Jingqin Chen Bohan Zhang Di Li Ding Zhou Pengtao Jing Guiying Xu Yingli Wang Kateřina Holá Dezhen Shen Changfeng Wu Liang Song Chengbo Liu Radek Zbořil Songnan Qu | 2018 | Light(Science & Applications)2018，7，1： | 13 |
| 5 | Using borehole core analysis to reveal Late Quaternary paleoearthquakes along the Nankou-Sunhe Fault,Beijing显示文摘The Nankou-Sunhe Fault is a buried active normal fault that traverses the urban area of Beijing.Its seismic risks have caused considerable concerns.This paper studies paleoearthquakes along this fault by analyzing and correlating bore-hole cores obtained from triple-tube coring,incorporating experience acquired from trenching.As a result,a model for identifying earthquake-derived colluvium by sediment-core analysis is proposed.Triple-tube coring technique is useful to collect continuous undis-turbed soil core near the Nankou-Sunhe Fault.By identifying fault-scarp colluviums,determining cumulative displacement,and analysing stratum thickening on the hanging wall,we are able to establish a preliminary paleoearthquake sequence consisting of 13 surface-rupturing events since 60 ka.The seismic history can be divided into three periods based on different recurrence intervals.Between 60 and 40 ka,three earthquakes occurred with recurrence interval of ~10 ka.From 40 to 25 ka,there were six earthquakes with the recurrence interval of about 2.5 ka.In the last 25 ka,four earthquakes have taken place with the recurrence interval varying considerably.The recurrence interval between the last three events is ~5 ka.Smaller recurrence intervals correspond to stages of faster fault slip.The coseismic displacement of a single event is 0.8 to 2.2 m,average 1.4 m,largely equivalent to moment magnitudes 6.7-7.1.This study demonstrates the feasibility of bore-hole drilling in investigating paleoearthquakes along normal faults.It also suggests that closely spaced boreholes with continuous undisturbed cores are essential for reconstructing the complete paleoearthquake sequence. | ZHANG ShiMin WANG DanDan LIU XuDong ZHANG GuoHong ZHAO JunXiang LUO MingHui REN JunJie WANG Rui ZHANG YingLi | 2008 | Science China Earth Sciences2008，51，8： | 11 |
| 6 | Geochronology and Geochemistry of Mafic Rocks in the Xuhe, Shaanxi, China: Implications for Petrogenesis and Mantle Dynamics显示文摘The Xuhe mafic rocks, located in Ziyang county of Shaanxi Province, are dominated by diabase-porphyrite, gabbro–diabase, diabase, and pyroxene diorite. Primitive mantle-normalized multi-element patterns show that, the Xuhe mafic rocks are enriched in large ion lithophile elements(LITE), such as Ba and Pb, depleted in K and Sr for basic rocks, and are depleted in Sr, P and Ti for pyroxene diorite. Chondrite-normalized REE patterns display LREE enrichment(LaN/YbN = 9.34–13.99) and have normalized patterns for trace element and REE similar to that of typical OIB. Detailed SIMS zircon U–Pb dating yields emplacement ages of 438.4 ± 3.1 Ma for Xuhe mafic rocks. The relatively low Mg O(basic rock: 3.11–7.21 wt%; pyroxene diorite: 0.89–1.21 wt%) and Mg#(0.20–0.49) for Xuhe mafic rocks suggest that they were possibly originated from an extremely evolved magma. The rising parental mafic magmas underwent pyroxene and plagioclase fractionation. Crustal contamination of pyroxene diorite before emplacement occurred at a higher crustal level compared to other lithology in Xuhe mafic rocks. The degree of partial melt was low(5%–10%) and in garnetspinel transition facies. Sr-Nd isotope of pyroxene diorite and enrichment mantle characteristics for Xuhe mafic rocks suggest that mafic rocks in the North Daba Mountains were derived from a mixture of HIMU, EMII and small amount of EMI components. Furthermore, this study discusses mantle geodynamic significance of Xuhe mafic rocks in the Silurian, which indicates subduction and uplift of magma caused back-arc extension. | WANG Kunming WANG Zongqi ZHANG Yingli WANG Gang | 2015 | Acta Geologica Sinica(English Edition)2015，89，1： | 9 |
| 7 | Microvascular protective role of pericytes in melatonin-treated spinal cord injury in the C57BL/6 mice显示文摘 | Jing Yingli Wu Qingbin Yuan Xiaochen Li Bingwei Liu Mingming Zhang Xiaoyan Liu Shuying Li Hongwei Xiu Ruijuan | 2014 | Chinese Medical Journal2014，，15： | 9 |
| 8 | Repetitive transcranial magnetic stimulation for hallucination in schizophrenia spectrum disorders A meta-analysis显示文摘OBJECTIVE:This study assessed the efficacy and tolerability of repetitive transcranial magnetic stimulation for treatment of auditory hallucination of patients with schizophrenia spectrum disorders.DATA SOURCES:Online literature retrieval was conducted using PubMed,ISI Web of Science,EMBASE,Medline and Cochrane Central Register of Controlled Trials databases from January1985 to May 2012.Key words were'transcranial magnetic stimulation','TMS','repetitive transcranial magnetic stimulation',and'hallucination'.STUDY SELECTION:Selected studies were randomized controlled trials assessing therapeutic efficacy of repetitive transcranial magnetic stimulation for hallucination in patients with schizophrenia spectrum disorders.Experimental intervention was low-frequency repetitive transcranial magnetic stimulation in left temporoparietal cortex for treatment of auditory hallucination in schizophrenia spectrum disorders.Control groups received sham stimulation.MAIN OUTCOME MEASURES:The primary outcome was total scores of Auditory Hallucinations Rating Scale,Auditory Hallucination Subscale of Psychotic Symptom Rating Scale,Positive and Negative Symptom Scale-Auditory Hallucination item,and Hallucination Change Scale.Secondary outcomes included response rate,global mental state,adverse effects and cognitive function.RESULTS:Seventeen studies addressing repetitive transcranial magnetic stimulation for treatment of schizophrenia spectrum disorders were screened,with controls receiving sham stimulation.All data were completely effective,involving 398 patients.Overall mean weighted effect size for repetitive transcranial magnetic stimulation versus sham stimulation was statistically significant(MD=–0.42,95%CI:–0.64 to–0.20,P=0.000 2).Patients receiving repetitive transcranial magnetic stimulation responded more frequently than sham stimulation(OR=2.94,95%CI:1.39 to 6.24,P=0.005).No significant differences were found between active repetitive transcranial magnetic stimulation and sham stimulation for positive or negative symptoms.Compared with sham stimulation,active repetitive transcranial magnetic stimulation had equivocal outcome in cognitive function and commonly caused headache and facial muscle twitching.CONCLUSION:Repetitive transcranial magnetic stimulation is a safe and effective treatment for auditory hallucination in schizophrenia spectrum disorders. | Yingli Zhang Wei Liang Shichang Yang Ping Dai Lijuan Shen Changhong Wang | 2013 | Neural Regeneration Research2013，8，28： | 8 |
| 9 | Rb-Sr and Sm-Nd Isochron Ages of the Dongmozhazhua and Mohailaheng Pb-Zn Ore Deposits in the Yushu area, southern Qinghai and Their Geological Implications显示文摘Located on the northeast margin of the Qiangtang terrane between the Jinshajiang suture zone and Bangonghu-Nujiang suture zone, the Dongmozhazhua and Mohailaheng Pb-Zn deposits in the Yushu area of Qinghai Province are representative Pb-Zn deposits of the Pb-Zn-Cu polymetallic mineralization belt in the northern part of the Nujiang-Lancangjiang-Jinshajiang area, which are in the front belt of the Yushu thrust nappe system. The formed environments of these two deposits are different from those of sediment-hosted base metal deposits elsewhere in the world. The authors hold that they were formed during the Indian-Asian continental collision and developed within the foldthrust belt combined with thrust and strike-slip-related Cenozoic basins in the interior of the collisional zone. Studying on the metallogenic epochs of these two deposits is helpful to the understanding of ore-forming regularity of the regional Pb-Zn-Cu mineralization belt and also to the search for new deposits in this region. The age of the Dongmozhazhua deposit has been determined by the Rb-Sr isochron method for sphalerite residues, whereas the age of the Mohailaheng deposit has been determined by the Rb-Sr isochron method for sphalerite residues and the Sm-Nd isochron method for fluorite. The age of the Dongmozhazhua deposit is 35.0±0.0 Ma((87Sr/86Sr)0=0.708807) for sphalerite residues. The age of the Mohailaheng deposit is 32.2±0.4 Ma((87Sr/86Sr)0=0.708514) for sphalerite residues and 31.8±0.3 Ma((143Nd/144Nd)0=0.512362) for fluorite with an average of 32.0 Ma. Together with the regional geological setting during mineralization, a possible tectonic model for metallogeny of the Dongmozhazhua and Mohailaheng Pb-Zn deposits has been established. These two ages are close to the ages of the Pb-Zn deposits in the Lanping and Tuotuohe basins, indicating that it is possible that the narrow 1000-kilometer-long belt controlled by a thrust nappe system on the eastern and northern margins of the Tibetan plateau could be a giant Pb-Zn mineralized belt. | TIAN Shihong GONG Yingli YANG Zhusen HOU Zengqian LIU Yingchao SONG Yucai XUE Wanwen LU Haifeng WANG Fuchun ZHANG Yubao ZHU Tian YU Changjie | 2014 | Acta Geologica Sinica(English Edition)2014，88，2： | 8 |
| 10 | Crosstalk-free achromatic full Stokes imaging polarimetry metasurface enabled by polarization-dependent phase optimization显示文摘Imaging polarimetry is one of the most widely used analytical technologies for object detection and analysis.To date,most metasurface-based polarimetry techniques are severely limited by narrow operating bandwidths and inevitable crosstalk,leading to detrimental effects on imaging quality and measurement accuracy.Here,we propose a crosstalkfree broadband achromatic full Stokes imaging polarimeter consisting of polarization-sensitive dielectric metalenses,implemented by the principle of polarization-dependent phase optimization.Compared with the single-polarization optimization method,the average crosstalk has been reduced over three times under incident light with arbitrary polarization ranging from 9μm to 12μm,which guarantees the measurement of the polarization state more precisely.The experimental results indicate that the designed polarization-sensitive metalenses can effectively eliminate the chromatic aberration with polarization selectivity and negligible crosstalk.The measured average relative errors are 7.08%,8.62%,7.15%,and 7.59%at 9.3,9.6,10.3,and 10.6μm,respectively.Simultaneously,the broadband full polarization imaging capability of the device is also verified.This work is expected to have potential applications in wavefront detection,remote sensing,light-field imaging,and so forth. | Yaxin Zhang Mingbo Pu Jinjin Jin Xinjian Lu Yinghui Guo Jixiang Cai Fei Zhang Yingli Ha Qiong He Mingfeng Xu Xiong Li Xiaoliang Ma Xiangang Luo | 2022 | Opto-Electronic Advances2022，5，11： | 6 |
| 11 | A pair of transposon-derived proteins function in a histone acetyltransferase complex for active DNA demethylation显示文摘Transposons 被 epigenetic 机制通常包括 DNA methylation 使沉默。这里,我们识别了一双先驱导出 transposon 的蛋白质(HDP ) , HDP1 和 HDP2,在 Arabidopsis 的反沉默因素。hdp1 和 hdp2 异种显示了 transgenes 和某 transposons 的提高的 silencing。种系发生的分析表明 HDP1 和 HDP2 分别地从先驱编码 transposon 的 transposase 和 DNA 有约束力的蛋白质被共同驯养。HDP1 在原子核与 HDP2 交往,类似于他们的 transposon 对应物。而且, HDP1 和 HDP2 与组成在 DNA demethylation 工作的 histone acetyltransferase 建筑群的 IDM1, IDM2, IDM3 和 MBD7 被联系。HDP2 和 methyl-DNA-binding 蛋白质 MBD7 分享普通 genomic 绑定地点的一个大集合,显示他们联合决定 histone acetyltransferase 建筑群的目标特性。因此,我们的数据表明 HDP1 和 HDP2 组成被招募了到 histone acetyltransferase 建筑群阻止 DNA hypermethylation 和 epigenetic silencing 的一个功能的模块。 | Cheng-Guo Duan Xingang Wang Shaojun Xie Li Pan Daisuke Miki Kai Tang Chuan-Chih Hsu Mingguang Lei Yingli Zhong Yueh-Ju Hou ZhijuanWang Zhengjing Zhang Satendra K Mangrauthia Huawei Xu Heng Zhang Brian Dilkes W Andy Tao Jian-Kang Zhu | 2017 | Cell Research2017，27，2： | 6 |
| 12 | Insular Cortex is Critical for the Perception, Modulation,and Chronification of Pain显示文摘An increasing body of neuroimaging and electrophysiological studies of the brain suggest that the insular cortex(IC) integrates multimodal salient information ranging from sensation to cognitive-affective events to create conscious interoception. Especially with regard to pain experience, the IC has been supposed to participate in both sensory-discriminative and affective-motivational aspects of pain. In this review, we discuss the latest data proposing that subregions of the IC are involved in isolated pain networks: the posterior sensory circuit and the anterior emotional network. Due to abundant connections with other brain areas, the IC is likely to serve as an interface where cross-modal shaping of pain occurs. In chronic pain,however, this mode of emotional awareness and the modulation of pain are disrupted. We highlight some of the molecular mechanisms underlying the changes of the pain modulation system that contribute to the transition from acute to chronic pain in the IC. | Changbo Lu Tao Yang Huan Zhao Ming Zhang Fancheng Meng Hao Fu Yingli Xie Hui Xu | 2016 | Neuroscience Bulletin2016，32，2： | 6 |
| 13 | GATA family members as inducers for cellular reprogramming to pluripotency显示文摘GATA 蛋白质家庭的成员在系说明和 transdifferentiation 起重要作用。以前的报告证明 GATA 蛋白质家庭罐头的一些成员也由代替 Oct4 在体的房间导致 pluripotency,一个关键联系 pluripotency 的因素。然而,连接指定系的暗示的机制和 pluripotency 的激活留下逃犯。这里,我们报导所有 GATA 家庭成员能代替让 Oct4 导致 pluripotency。我们发现 GATA 家庭的所有成员能禁止 overrepresented ectodermal 系基因,它与以前的报告显示不同指定系的力量的平衡为 pluripotency 的恢复是重要的一致。一根保存锌手指在 C 终点的 DNA 有约束力的领域是批评的让 GATA 家庭导致 pluripotency。用 RNA-seq 和 ChIP-seq,我们决定 pluripotency 相关的基因 Sall4 在 reprogramming 期间是 GATA 家庭成员的一个直接目标并且用作连接指定系的 GATA 家庭到 pluripotency 电路的一座桥。因此, GATA 家庭是所有成员能作为 reprogramming 进程的 inducers 工作并且能代替 Oct4 的第一个蛋白质家庭。我们的结果建议在 reprogramming 的 GATA 家庭的角色被低估了并且 GATA 家庭可以担任房间命运变换的一个重要调停人。 | Jian Shu Ke Zhang Minjie Zhang Yao Sida Shao Fengxia Du Caiyun Yang Wenhan Chen Chen Wu Weifeng Yang Yingli Sun Hongkui Deng | 2015 | Cell Research2015，25，2： | 5 |
| 14 | Effects of biochar amendment in two soils on greenhouse gas emissions and crop production显示文摘 | Jinyang Wang Xiaojian Pan Yinglie Liu Xiaolin Zhang Zhengqin Xiong | 2012 | Plant and Soil2012，，1： | 5 |
| 15 | Injectable dual glucose-responsive hydrogel-micelle composite for mimicking physiological basal and prandial insulin delivery显示文摘For type 1 and advanced type 2 diabetic patients, insulin replacement therapy with simulating on-demand prandial and basal insulin secretion is the best option for optimal glycemic control. However, there is no insulin delivery system yet could mimic both controlled basal insulin release and rapid prandial insulin release in response to real-time blood glucose changes. Here we reported an artificial insulin delivery system, mimicking physiological basal and prandial insulin secretion, to achieve real-time glycemic control and reduce risk of hypoglycemia. A phenylboronic acid(PBA)/galactosyl-based glucose-responsive insulin delivery system was prepared with insulin-loaded micelles embedded in hydrogel matrix. At the hyperglycemic state, both the hydrogel and micelles could swell and achieve rapid glucose-responsive release of insulin, mimicking prandial insulin secretion.When the glucose level returned to the normal state, only the micelles partially responded to glucose and still released insulin gradually. The hydrogel with increased crosslinking density could slow down the diffusion speed of insulin inside, resulting in controlled release of insulin and simulating physiological basal insulin secretion. This hydrogel-micelle composite insulin delivery system could quickly reduce the blood glucose level in a mouse model of type 1 diabetes, and maintain normal blood glucose level without hypoglycemia for about 24 h. This kind of glucose-responsive hydrogel-micelle composite may be a promising candidate for delivery of insulin in the treatment of diabetes. | Juan Lv Gang Wu Ying Liu Chang Li Fan Huang Yumin Zhang Jinjian Liu Yingli An Rujiang Ma Linqi Shi | 2019 | Science China Chemistry2019，62，5： | 5 |
| 16 | Melting and shrinkage of cryosphere in Tibet and its impact on the ecological environment显示文摘Global warming is having a profound impact on global ecological systems,and has inevitably induced changes in the cryosphere,one of the five layers of the earth.Major changes include the shrinking and reduction in the area and volume of both the mountain glaciers and the ice caps covering the North and South poles,and the melting of permafrost and thickening of the active frost layer.Swift changes in the cryosphere have inevitably induced ecological and environmental changes in its zone.While some of these changes are beneficial to mankind,such as an increase in water circulation,short term increases in water volumes and the enlargement of the cultivatable area,others are extremely hazardous,like the flooding of lowlands caused by an increased sea level elevation,debris flow caused by glaciers,glacier lake bursts,undermined building safety caused by permafrost melting,the deterioration of alpine cold meadows,and the surface aridization and desertification of land.Tibet,having a major part of the cryosphere in China,is home to the most widely spread glaciers and permafrost,which play a vital role in regulating water resources,climate,environment and the ecological safety in China and Asia.However,due to global warming,the glaciers and permafrost in Tibet have recently changed dramatically,exhibiting shrinkage and melting,which threatens long-term water resources,and the ecological and environmental safety of China.Based on existing research,this paper discusses the relationship between global warming and the melting and shrinkage of the cryosphere.The results show that the cryosphere's melting and shrinkage in Tibet are the direct result of global warming.The melting of glaciers has led to a series of disasters,such as changes in river runoff,the heightened frequency of debris flows induced by glaciers and the outbursts of glacier lakes.The melting of the permafrost also resulted in a series of ecological and environmental problems in Tibet,such as the degradation and population succession of the alpine grassland and meadows,the aridization of the land surface,and the occurrence of freeze-thaw erosion. | JianGuo ZHANG YingLi WANG YunSong JI DeZhi YAN | 2011 | Journal of Arid Land2011，3，4： | 4 |
| 17 | The function and regulation of OTU deubiquitinases显示文摘Post-translational modification of cellular proteins by ubiquitin regulates numerous cellular processes,including cell division,immune responses,and apoptosis.Ubiquitin-mediated control over these processes can be reversed by deubiquitinases(DUBs),which remove ubiquitin from target proteins and depolymerize polyubiquitin chains.Recently,much progress has been made in the DUBs.In humans,the ovarian tumor protease(OTU)subfamily of DUBs includes 16 members,most of which mediate cell signaling cascades.These OTUs show great variation in structure and function,which display a series of mechanistic features.In this review,we provide a comprehensive analysis of current progress in character,structure and function of OTUs,such as the substrate specificity and catalytic activity regulation.Then we discuss the relationship between some diseases and OTUs.Finally,we summarize the structure of viral OTUs and their function in immune escape and viral survival.Despite the challenges,OTUs might provide new therapeutic targets,due to their involvement in key regulatory processes. | Jiansen Du Lin Fu Yingli Sui Lingqiang Zhang | 2020 | Frontiers of Medicine2020，14，5： | 4 |
| 18 | Commercialized non-Camellia tea:traditional function and molecular identification显示文摘Non-Camellia tea is a part of the colorful Chinese tea culture,and is also widely used as beverage and medicine in folk for disease prevention and treatment.In this study,37 samples were collected,including 33 kinds of non-Camellia teas and 4 kinds of teas(Camellia).Traditional functions of non-Camellia teas were investigated.Furthermore,non-Camellia teas of original plants were characterized and identified by molecular methods.Four candidate regions(rbcL,matK,ITS2,psbA-trnH)were amplified by polymerase chain reaction.In addition,DNA barcodes were used for the first time to discriminate the commercial non-Camellia tea and their adulterants,and to evaluate their safety.This study showed that BLASTN and the relevant phylogenetic tree are efficient tools for identification of the commercial non-Camellia tea and their adulterants.However,some sequences from original plants have not been found and there is a limitation of sequence number of original plants in GenBank.Submitting more original plant sequences to the GenBank will be helpful for evaluating the safety of non-Camellia teas. | Ping Long Zhanhu Cui Yingli Wang Chunhong Zhang Na Zhang Minhui Li Peigen Xiao | 2014 | Acta Pharmaceutica Sinica B2014，4，3： | 3 |
| 19 | Equilibrium between Clinopyroxene and Host Rocks:Implication for the Magmatic Source and Evolution of Alkali Basalts of the Taohekou Formation in the Northern Daba Mountains,China显示文摘Taohekou 形成是在北 Daba 山在早志留纪形成的一个暴烈沉积的岩层,中国。与主导的碱暗岩和次要的披风捕虏体,暴烈的岩石在 clinopyroxene 斑晶被充实。Geochemical 分析证明从不同岩相的 clinopyroxenes 的作文有一种靠近的亲密关系。从到 amygdaloidal 暗岩的粗糙的斑状的暗岩,枕头或好斑状的暗岩有在 clinopyroxenes (包括的斑晶, microcrystal 和 xenocryst ) 的作文在场的班机关联。所有 clinopyroxenes 除了在披风捕虏体的 clinopyroxenes,显示出踪迹元素和 REE 的一个类似的模式,它显示他们是从血缘的岩浆的连续部分结晶化的可能的产品。然而,在披风捕虏体的 Clinopyroxenes 是披风 xenocrysts。clinopyroxenes 的结晶化压力逐渐地从披风捕虏体,深层的 xenocryst,粗糙的 porphritic 暗岩,枕头或好 porphritic 暗岩减少,到 amygdaloidal 暗岩,它分别地是 1.924.41 GPa, 1.182.36 GPa, 1.132.05 GPa, 0.440.62 GPa 和 0.140.28 GPa。计算结果建议主要岩浆比 68 km 深从一个披风区域发源并且在 3768 km, 1520 km 和 59 km 的间隔停滞在期间它的上升。碱暗岩被增加 Si 的集中描绘并且与 magmatic 进化碱。同时,他们显著地在 LREE 被充实,并且踪迹元素和 REE 的模式类似于海洋的岛暗岩的那些。 | XIANG Zhongjin YAN Quanren YAN Zhen WANG Zongqi WANG Tao ZHANG Yingli QIN Xiaofeng | 2011 | Acta Geologica Sinica(English Edition)2011，85，1： | 3 |
| 20 | Discovery of late Paleozoic fossils in tectonic blocks of the Dabao Formation in the South Qinling Orogenic Belt and their significance显示文摘The Dabao Formation in the South Qinling Orogenic Belt was previously regarded as Ordovician in age and consists of clastic matrix and blocks of siltstone,limestone,chert,and volcanic rocks.However,some Middle Devonian corals,conodonts,and other fossil fragments within the limestone blocks were discovered in recent field investigations,indicating that the Dabao Formation was formed during late Paleozoic.Combined with other regional geological data,the Dabao Formation in the Southern Qinling Orogenic Belt is considered to be a late Paleozoic or early Mesozoic accretionary complex. | WANG Tao WANG ZongQi YAN Zhen YAN QuanRen ZHANG YingLi XIANG ZhongJin | 2011 | Science China Earth Sciences2011，54，7： | 3 |
您所在的机构暂未开通此部分的功能，请联系管理员