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| 1 | Pathogenicity of a currently circulating Chinese variant pseudorabies virus in pigs显示文摘AIM:To test the pathogenicity of pseudorabies virus(PRV)variant HN1201 and compare its pathogenicity with a classical PRV Fa strain.METHODS:The pathogenicity of the newly-emerging PRV variant HN1201 was evaluated by different inoculating routes,virus loads,and ages of pigs.The classical PRV Fa strain was then used to compare with HN1201 to determine pathogenicity.Clinical symptoms after virus infection were recorded daily and average daily body weight was used to measure the growth performance of pigs.At necropsy,gross pathology and histopathology were used to evaluate the severity of tissue damage caused by virus infection.RESULTS:The results showed that the efficient infection method of RPV HN1201 was via intranasal inoculation at 107 TCID50,and that the virus has high pathogenicity to 35-to 127-d old pigs.Compared with Fa strain,pigs infected with HN1201 showed more severe clinical symptoms and pathological lesions.Immunochemistry results revealed HN1201 had more abundant antigen distribution in extensive organs.CONCLUSION:All of the above results suggest that PRV variant HN1201 was more pathogenic to pigs than the classical Fa strain. | Qing-Yuan Yang Zhe Sun Fei-Fei Tan Ling-Hua Guo Yu-Zhou Wang Juan Wang Zhi-Yan Wang Li-Lin Wang Xiang-Dong Li Yan Xiao Ke-Gong Tian | 2016 | World Journal of Virology2016，5，1： | 31 |
| 2 | Neddylation of PTEN regulates its nuclear import and promotes tumor development显示文摘PTEN tumor suppressor opposes the PI3K/Akt signaling pathway in the cytoplasm and maintains chromosomal integrity in the nucleus.Nucleus–cytoplasm shuttling of PTEN is regulated by ubiquitylation,SUMOylation and phosphorylation,and nuclear PTEN has been proposed to exhibit tumor-suppressive functions.Here we show that PTEN is conjugated by Nedd8 under high glucose conditions,which induces PTEN nuclear import without effects on PTEN stability.PTEN neddylation is promoted by the XIAP ligase and removed by the NEDP1 deneddylase.We identify Lys197 and Lys402 as major neddylation sites on PTEN.Neddylated PTEN accumulates predominantly in the nucleus and promotes rather than suppresses cell proliferation and metabolism.The nuclear neddylated PTEN dephosphorylates the fatty acid synthase(FASN)protein,inhibits the TRIM21-mediated ubiquitylation and degradation of FASN,and then promotes de novo fatty acid synthesis.In human breast cancer tissues,neddylated PTEN correlates with tumor progression and poor prognosis.Therefore,we demonstrate a previously unidentified pool of nuclear PTEN in the Nedd8-conjugated form and an unexpected tumor-promoting role of neddylated PTEN. | Ping Xie Zhiqiang Peng Yujiao Chen Hongchang Li Mengge Du Yawen Tan Xin Zhang Zhe Lu Chun-Ping Cui Cui Hua Liu Fuchu He Lingqiang Zhang | 2021 | Cell Research2021，31，3： | 11 |
| 3 | Amine-based solvent for CO_2 absorption and its impact on carbon steel corrosion: A perspective review显示文摘Carbon dioxide(CO2)is one of the commonly emitted gaseous by-products in industrial processes.While CO2 gas is the main cause to greenhouse effect,various CO2 capture technologies have been proposed and implemented to sequester the CO2 before the waste gases being released into the atmosphere.One of the mature technologies for CO2 absorption is by using amine-based solvents.In this regard,different single amine solvents or blended amine solvents have been proven for their capability to remove CO2.However,the dissolution and reaction of CO2 gas with the amine solvents turn the solution corrosive.Such phenomenon is undesired as it posts corrosion problem to the absorption column,which normally built of carbon steel material.Henceforth,understanding the behaviour of different amine-based solvents in absorbing CO2 and its subsequent impact on carbon steel corrosion is very significant.In this review article,we will outline some of the more commonly used solvents and their respective advantages and disadvantages,motivating further investigation into the corrosion tendency.Meanwhile,existing gaps in this research area are discussed for future investigation. | Zhe Lun Ooi Pui Yee Tan Lian See Tan Swee Pin Yeap | 2020 | Chinese Journal of Chemical Engineering2020，28，5： | 7 |
| 4 | Emission characteristics of offshore fishing ships in the Yellow Bo Sea, China显示文摘Maritime transport has been playing a decisive role in global trade. Its contribution to the air pollution of the sea and coastal areas has been widely recognized. The air pollutant emission inventories of several harbors in China have already been established. However,the emission factors of local ships have not been addressed comprehensively, and thus are lacking from the emission inventories. In this study, on-board emission tests of eight diesel-powered offshore fishing ships were conducted near the coastal region of the northern Yellow Bo Sea fishing ground of Dalian, China. Results show that large amounts of fine particles(< 0.5 μm, 90%) were found in maneuvering mode, which were about five times higher than those during cruise mode. Emission rates as well as emission factors based on both distance and fuel were determined during the cruise and maneuvering modes(including departure and arrival). Average emission rates and distance-based emission factors of CO, HC and PM were much higher during the maneuvering mode as compared with the cruise mode. However, the average emission rate of Nitrous Oxide(NOx) was higher during the cruise mode as compared with the maneuvering modes. On the contrary, the average distance-based emission factors of NOxwere lower during the cruise mode relative to the maneuvering mode due to the low sailing speed of the latter. | Yingshuai Liu Yunshan Ge Jianwei Tan Mingliang Fu Asad Naeem Shah Luqiang Li Zhe Ji Yan Ding | 2018 | Journal of Environmental Sciences2018，30，3： | 5 |
| 5 | Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection显示文摘Structural principles underlying the composition and synergistic mechanisms of protective monoclonal antibody cocktails are poorly defined.Here,we exploited antibody cooperativity to develop a therapeutic antibody cocktail against SARS-CoV-2.On the basis of our previously identified humanized cross-neutralizing antibody H014,we systematically an a lyzed a fully human n aive antibody library and rationally identified a potent neutralizing antibody partner,P17,which confers effective protection in animal model.Cryo-EM studies dissected the nature of the P17 epitope,which is SARS-CoV-2 specific and distinctly different from that of HOI4.High-resolution structure of the SARS-CoV-2 spike in complex with HOM and P17,together with functional investigations revealed that in a two-antibody cocktail,synergistic neutralization was achieved by S1 shielding and conformational locking,thereby blocking receptor attachment and viral membrane fusion,conferring high potency as well as robustness against viral mutation escape.Furthermore,cluster analysis identified a hypothetical 3rd antibody partner for further reinforcing the cocktail as pan-SARS-CoVs therapeutics. | Hangping Yao Yao Sun Yong-Qiang Deng Nan Wang Yongcong Tan Na-Na Zhang Xiao-Feng Li Chao Kong Yan-Peng Xuc Qi Chen Tian-Shu Cao Hui Zhao Xintian Yan Lei Cao Zhe Lv Dandan Zhu Rui Feng Nanping Wu Wenhai Zhang Yuhao Hu Keda Chen Rong-Rong Zhang Qingyu Lv Shihui Sun Yunhua Zhou Run Yan Guan Yang Xinglu Chanjuan Liu Xiangyun Lu Linfang Cheng Hongying Qiu Xing-Yao Huang Tianhao Weng Danrong Shi Weidong Jiang Junbin Shao Lei Wang Jie Zhang Tao Jiang Guojun Lang Cheng-Feng Qinc Lanjuan Li Xiangxi Wang | 2021 | Cell Research2021，31，1： | 5 |
| 6 | Inhibition of DNA restrictive endonucleases and Taq DNA polymerase by trimalonic acid C_(60)显示文摘Activities of trimalonic acid fullerene (TMA C_60) on DNA restrictive enzymatic reaction were investigated by using two restrictive endonucleases Hind III and EcoR I and plasmid pEGFP-N1 with single restric-tive site for both enzymes. Meanwhile, TMA C60 was also tested to clarify its effects on polymerase chain reaction (PCR) with the catalyst of Taq DNA polymerase and the template of plasmid pEGFP-N1. The products from restrictive reactions or PCR were detected by agarose gel electrophoresis. It was found that the product amounts from restrictive reactions or PCR decreased significantly with addition of TMA C60. The inhibition by TMA C60 was dose-dependent and IC50 values for reactions of Hind III, EcoR I and PCR were 16.3, 6.0 and 6.0 μmol/L, respectively. Addition of two scavengers of reactive oxygen species (ROS), L-ascorbic acid-2-phosphate ester magnesium and sodium azide at the con-centrations of 2―10 mmol/L did not antagonize the activities of TMA C60 against PCR and two restrictive reactions. However, increase of Taq DNA polymerase amounts in PCR system antagonized the activities of TMA C60. These data implied that TMA C60 was able to inhibit the activities of the three above-mentioned enzymes involved in DNA metabolism, and that this inhibition probably did not correlate to ROS. | YANG XinLin CHEN Zhe MENG XianMei LI Bo TAN Xin | 2007 | Chinese Science Bulletin2007，52，13： | 4 |
| 7 | (±)-Zanthonitidine A,a Pair of Enantiomeric Furoquinoline Alkaloids from Zanthoxylum nitidum with Antibacterial Activity显示文摘A pair of new enantiomeric furoquinoline alkaloids,(±)-zanthonitidine A(1),together with nine known ones(2-10)were isolated from the radix of Zanthoxylum nitidum.Their chemical structures were elucidated based on the extensive spectroscopic analysis.The racemic mixture of 1 was separated by chiral column chromatography,and the absolute configurations of (+)-1 and(-)-1 were determined by the comparison of experimental and calculated electronic circular dichroism spectra.Antibacterial activities of compounds 1-9 were evaluated,and compounds(+)-1,(-)-1,3,7 and 8 showed antibacterial activities against Bacillus subtilis,Enterococcus faecalis or Staphylococcus aureus. | Li-Na Zhao Xi-Xi Guo Shuai Liu Li Feng Qi-Rui Bi Zhe Wang Ning-Hua Tan | 2018 | Natural Products and Bioprospecting2018，8，5： | 3 |
| 8 | A super pan-genomic landscape of rice显示文摘Pan-genomes from large natural populations can capture genetic diversity and reveal genomic complexity.Using de novo longread assembly,we generated a graph-based super pan-genome of rice consisting of a 251-accession panel comprising both cultivated and wild species of Asian and African rice.Our pan-genome reveals extensive structural variations(SVs)and gene presence/absence variations.Additionally,our pan-genome enables the accurate identification of nucleotide-binding leucine-rich repeat genes and characterization of their inter-and intraspecific diversity.Moreover,we uncovered grain weight-associated SVs which specify traits by affecting the expression of their nearby genes.We characterized genetic variants associated with submergence tolerance,seed shattering and plant architecture and found independent selection for a common set of genes that drove adaptation and domestication in Asian and African rice.This super pan-genome facilitates pinpointing of lineage-specific haplotypes for trait-associated genes and provides insights into the evolutionary events that have shaped the genomic architecture of various rice species. | Lianguang Shang Xiaoxia Li Huiying He Qiaoling Yuan Yanni Song Zhaoran Wei Hai Lin Min Hu Fengli Zhao Chao Zhang Yuhua Li Hongsheng Gao Tianyi Wang Xiangpei Liu Hong Zhang Ya Zhang Shuaimin Cao Xiaoman Yu Bintao Zhang Yong Zhang Yiqing Tan Mao Qin Cheng Ai Yingxue Yang Bin Zhang Zhiqiang Hu Hongru Wang Yang Lv Yuexing Wang Jie Ma Quan Wang Hongwei Lu Zhe Wu Shanlin Liu Zongyi Sun Hongliang Zhang Longbiao Guo Zichao Li Yongfeng Zhou Jiayang Li Zuofeng Zhu Guosheng Xiong Jue Ruan Qian Qian | 2022 | Cell Research2022，32，10： | 3 |
| 9 | TECHNOLOGY AND APPLICATION OF PRODUCT EVOLUTIONARY DESIGN BASED ON CONFIGURATION IN MASS CUSTOMIZATION MODE显示文摘Product customization has been recognized as an effective means to implement mass cus-tomization (MC). A new theory and method for MC-oriented evolutionary design of configuration product is presented based on the study of developing law of evolutionary design in integrated envi-ronment, which focuses on the innovation and reuse properties of configuration product. The key technologies for general requirement modeling in quick response to customer requirement, multi-level stepwise configuration optimization driven by customer requirement and evolutionary deduction of product variable structure based on configuration association are thoroughly investigated. The suc-cessful application of the presented method in the development of real-life products demonstrates its utility, flexibility and robusticity. | FENG Yixiong CHENG Jin TAN Jianrong ZHENG Bing WEI Zhe | 2007 | Chinese Journal of Mechanical Engineering2007，20，3： | 3 |
| 10 | Overcoming the limitation of in-situ microstructural control in laser additive manufactured Ti-6Al-4V alloy to enhanced mechanical performance by integration of synchronous induction heating显示文摘Although a variety of processing routes were developed to in-situ manipulate microstructure for fabricating high-performance Ti-6Al-4 V alloy by directed energy deposition(DED),the in-situ microstructural control ability has been limited and lead to a narrowed mechanical property control range.This work proved the microstructural correlation betweenβ-grains andα-laths resulting from the unique thermal characteristics of DED for the first time and solved such a dilemma through synchronous induction heating assisted laser deposition(SILD)technology.The results confirmed that the laser energy and inductive energy have a different effect on the solidification and solid phase transformation conditions.By adjusting the laser-induction parameters,the microstructural correlation can be tuned;theβ-grains andα-laths can be controlled relatively separately,thereby significantly enhancing the ductility of as-deposited sample(elongation from 14.2%to 20.1%).Furthermore,the mechanical properties of the tuned microstructures are even comparable to that of DED Ti-6Al-4 V with post heat treatment,which indicates that the potential of SILD to be a one-step manufacturing process to fabricate high performance components without post heat treatment.Furthermore,the tensile testing results of the tuned microstructures indicate thatα-lath size is more influential on the mechanical properties than theβ-grain size due to its stronger hindering effect on the slipping of dislocations.This work promotes the understanding of the microstructural formation mechanism in DED titanium alloy and proves that the combination of synchronous induction and laser can expand the ability to control the microstructure and properties of multi-layer deposition. | Wei Fan Hua Tan Fengying Zhang Zhe Feng Yongxia Wang Lai-Chang Zhang Xin Lin Weidong Huang | 2021 | Journal of Materials Science & Technology2021，，35： | 3 |
| 11 | Enhancing bifunctionality of CoN nanowires by Mn doping for long-lasting Zn-air batteries显示文摘Tailoring the nanostructure and composition of transition metal nitrides is highly important for their use as potent low-cost electrocatalysts. Cobalt nitride(CoN) exhibits strong catalytic activity for oxygen evolution reaction(OER). However, its poor catalytic efficiency for oxygen reduction reaction(ORR) hinders its application in rechargeable zinc-air batteries(ZABs) as the air cathode. In this work, we deploy the effective strategy of Mn doping to improve both OER and ORR activity of CoN nanowires as the cathode material for ZAB. Theoretical calculation predicts that moderate Mn doping in cobalt nitride results in a downshift of the d-band center and reduces the adsorption energy of reaction intermediates. With ~10 at% Mn dopants, stronger catalysis activities for both OER and ORR are achieved compared to pure CoN nanowires. Subsequently, both aqueous and flexible quasi-solid-state ZABs are constructed using the Mn-doped CoN nanowires array as additive-free air cathode. Both types of devices present large open circuit potential, high power density and long-cycle stability. This work pushes forward the progress in developing cost-effective ZABs. | Yongqi Zhang Bo Ouyang Guankui Long Hua Tan Zhe Wang Zheng Zhang Weibo Gao Rajdeep Singh Rawat Hong Jin Fan | 2020 | Science China Chemistry2020，63，7： | 3 |
| 12 | Study protocol:A cross-sectional study on psychology and behavior investigation of Chinese residents,PBICR显示文摘Objective:This study protocol identifies the basic research route and framework of psychological and behavioral surveys among Chinese residents,aims establishing a database through a multicenter,large-sample cross-sectional survey in China to provide strong data support for research development in various fields and a more comprehensive and systematic understanding of the physical and mental health status of the public.Method:The study was conducted from June 20,2022 to August 31,2022,using stratified sampling and quota sampling methods,a total of 148 cities,202 districts and counties,390 townships/towns/sub-districts,and 780 communities/villages(excluding Hong Kong,Macao,and Taiwan)from 23 provinces,5 autonomous regions,and 4 municipalities directly under the central government in China were selected.The questionnaire was distributed one-on-one and face-to-face to the public by trained investigators,and the questionnaire included eight aspects:personal basic information,personal health status,family basic information,social environment in which they were located,psychological level scale,behavioral level scale,other scales,and attitude towards social hot issues.Data analysis will be performed after questionnaire return.Results:Data collection is ongoing.These findings will support physical and mental health research and strategy development in China and even globally,guiding policy-makers and health care organizations to reform their programs to ensure the best interests of residents and their families. | Yu-Jia Wang Ayidana Kaierdebieke Si-Yuan Fan Rui-Feng Zhang Meng-Jie Huang Han Li Xiao-Nan Sun Qi-Yu Li Wen-Jia Meng Wen-Yu Wu Zhi Lin Jing-Yao Liu Xin-Pei Wang Yun-Chou Wu Jing-Qi Tang Yi-Ke Sun Ke Chen Pu Ge Wai-Kit Ming Casper Zhang Zheng Feei Ma Lei Feng Xin-Yue Zhang Yu-Yao Niu Yu-Pei Yan Yi-Le Jin Guang-Ze Gao Shuang Dai Yu-Liu Li Yue Tan Yi-Wei Wu Qi Zhang Gui Gui Xian-Li Pan Yan-Ming Liao Xian-Qi Zhao Ya-Ting Zhang Hui-Yi Chen Yue-Wei Qiu Xiao-Min Fu Jiang-Ling Zhou Dan Li Ke-Han Li Meng-Wei Xu Zhe Wang Yue-Qi Wang Yong Ma Xin-Ying Sun Yi-Bo Wu | 2022 | Psychosomatic Medicine Research2022，4，3： | 3 |
| 13 | Mn-Based Two Dimensional Metal-Organic Framework Material from Benzimidazole-5,6-dicarboxylic Acid显示文摘新二维的金属器官的框架(MOF ) 结构被 MnCl 2·4H2 有 1H-benzimidazole-5,6-dicarboxylic 酸的 O (H 3 bidc ) 在 85 °C。结构被单个水晶的 X 光检查衍射,粉末 X 光检查衍射(PXRD ) ,红外线的光谱学(英尺红外) ,和 thermogravimetric 分析(TGA ) 描绘了。单个水晶的 X 光检查衍射分析表明这 MOF 是展出一个分层的 2D 网络,在不协调的羧基的氧原子之间的结合氢的相互作用和在咪唑戒指的 NH 组在最后的 3D 在起一个关键作用的五坐标的 Mn (II ) 混合物超分子的建筑学。这 MOF 显示出高热的稳定性直到 400 °C。而且,在在水里浸泡了以后, MOF 结构的 XRD 模式为多达 20 d 被保留,并且仅仅 MOF 的 2.8 wt% 在水里在开始的 48 h 以内被分解。 | Erpan Zhang Lili Zhang Zhe Tan Zhenguo Ji Qiaowei Li | 2016 | Chinese Journal of Chemistry2016，34，2： | 2 |
| 14 | On the robustness of EEG tensor completion methods显示文摘During the acquisition of electroencephalographic(EEG) signals, data may be missing or corrupted by noise and artifacts. To reconstruct the incomplete data, EEG signals are firstly converted into a three-order tensor(multi-dimensional data) of shape time × channel × trial. Then, the missing data can be efficiently recovered by applying a tensor completion method(TCM).However, there is not a unique way to organize channels and trials in a tensor, and different numbers of channels are available depending on the EEG setting used, which may affect the quality of the tensor completion results. The main goal of this paper is to evaluate the robustness of EEG completion methods with several designed parameters such as the ordering of channels and trials, the number of channels, and the amount of missing data. In this work, the results of completing missing data by several TCMs were compared. To emulate different scenarios of missing data, three different patterns of missing data were designed.Firstly, the amount of missing data on completion effects was analyzed, including the time lengths of missing data and the number of channels or trials affected by missing data. Secondly, the numerical stability of the completion methods was analyzed by shuffling the indices along channels or trials in the EEG data tensor. Finally, the way that the number of electrodes of EEG tensors influences completion effects was assessed by changing the number of channels. Among all the applied TCMs, the simultaneous tensor decomposition and completion(STDC) method achieves the best performance in providing stable results when the amount of missing data or the electrode number of EEG tensors is changed. In other words, STDC proves to be an excellent choice of TCM, since permutations of trials or channels have almost no influence on the complete results. The STDC method can efficiently complete the missing EEG signals. The designed simulations can be regarded as a procedure to validate whether or not a completion method is useful enough to complete EEG signals. | DUAN Feng JIA Hao ZHANG ZhiWen FENG Fan TAN Ying DAI YangYang CICHOCKI Andrzej YANG ZhengLu CAIAFA Cesar F. SUN Zhe SOLE-CASALS Jordi | 2021 | Science China(Technological Sciences)2021，64，9： | 2 |
| 15 | Laser powder bed fusion of high-strength Sc/Zr-modified Al–Mg alloy:phase selection,microstructural/mechanical heterogeneity,and tensile deformation behavior显示文摘Laser powder bed fusion(L-PBF)of Sc/Zr-modified Al-based alloys has recently become a promising method for developing a new generation of high-performance Al alloys.To clarify the modification roles of Sc/Zr elements,an Al–4.66Mg–0.48Mn–0.72Sc–0.33Zr(wt.%)alloy was processed using L-PBF.The effect of the local solidification condition of the molten pool on the precipitation behavior of primary Al_(3)(Sc,Zr)was analyzed based on time-dependent nucleation theory.It was found that primary Al_(3)(Sc,Zr)inevitably precipitated at the fusion boundary,while its precipitation could be effectively suppressed in the inner region of the molten pool.This subsequently induced the formation of a heterogeneousα-Al matrix.After direct aging,the heredity of solidification microstructure introduced heterogeneous secondary Al_(3)(Sc,Zr)precipitates withinα-Al matrix.Owing to the inverse relationship between grain boundary strengthening and precipitation strengthening,the direct-aged sample with dual heterogeneous structures exhibited reduced mechanical heterogeneity,resulting in lowered hetero-deformation-induced hardening.The low strain-hardening capability in the direct-aged sample promoted necking instability while inducing a large Lüders elongation,which effectively improved the tensile ductility. | Zihong Wang Xin Lin Nan Kang Jing Chen Hua Tan Zhe Feng Zehao Qin Haiou Yang Weidong Huang | 2021 | Journal of Materials Science & Technology2021，，36： | 2 |
| 16 | A mine drainage treatment system for AMD in remediation of metal sulfide mines显示文摘1. Objective In the process of mining, sorting and smelting metal sulfide mines, a large amount of acid mine drainage (AMD) containing concentrated sulfate (SO4 ^2-) and various metal elements (Fe, Mn, Cu, Zn, Ni, etc.) are produced. In order to solve current problems of mine acid drainage, we have improved the existing repair technology based on biogeochemical technology, and provided a new treatment system for AMD from metal sulfide mines. | Shi-Tian Hou Jing-Yi Cai Ke-Yan Tan Hong Yang Xin Hu Zhe Wang Xin Yuan | 2019 | China Geology2019，2，3： | 1 |
| 17 | A longitudinal analysis of innate and adaptive immune profile during hepatic flares in chronic hepatitis B显示文摘 | Anthony T. Tan Sarene Koh Winnie Goh Heng Yee Zhe Adam J. Gehring Seng Gee Lim Antonio Bertoletti | 2009 | Journal of Hepatology2009，，3： | 1 |
| 18 | Analytical Method for Main Cable Configuration of Tow-span Self-anchored Suspension Bridges显示文摘 | Tan Yonggang Gong Feng Zhang Zhe | 2009 | Structural Engineering and Mechanics2009，32，5： | 1 |
| 19 | High-speed multiwavelength InGaAs/InP quantum well nanowire array micro-LEDs for next generation optical communications显示文摘Miniaturized light sources at telecommunication wavelengths are essential components for on-chip optical communication systems.Here,we report the growth and fabrication of highly uniform p-i-n core-shell InGaAs/InP single quantum well(QW)nanowire array light emitting diodes(LEDs)with multi-wavelength and high-speed operations.Two-dimensional cathodoluminescence mapping reveals that axial and radial QWs in the nanowire structure contribute to strong emission at the wavelength of~1.35 and~1.55μm,respectively,ideal for low-loss optical communications.As a result of simultaneous contributions from both axial and radial QWs,broadband electroluminescence emission with a linewidth of 286 nm is achieved with a peak power of~17μW.A large spectral blueshift is observed with the increase of applied bias,which is ascribed to the band-filling effect based on device simulation,and enables voltage tunable multi-wavelength operation at the telecommunication wavelength range.Multi-wavelength operation is also achieved by fabricating nanowire array LEDs with different pitch sizes on the same substrate,leading to QW formation with different emission wavelengths.Furthermore,high-speed GHz-level modulation and small pixel size LED are demonstrated,showing the promise for ultrafast operation and ultracompact integration.The voltage and pitch size controlled multi-wavelength highspeed nanowire array LED presents a compact and efficient scheme for developing high-performance nanoscale light sources for future optical communication applications. | Fanlu Zhang Zhicheng Su Zhe Li Yi Zhu Nikita Gagrani Ziyuan Li Mark Lockrey Li Li Igor Aharonovich Yuerui Lu Hark Hoe Tan Chennupati Jagadish Lan Fu | 2023 | Opto-Electronic Science2023，2，5： | 1 |
| 20 | Accurate and robust estimation of phase error and its uncertainty of 50 GHz bandwidth sampling circuit显示文摘This paper discusses the dependence of the phase error on the 50 GHz bandwidth oscilloscope's sampling circuitry. We give the definition of the phase error as the difference between the impulse responses of the NTN (nose-to-nose) estimate and the true response of the sampling circuit. We develop a method to predict the NTN phase response arising from the internal sampling circuitry of the oscilloscope. For the default sampling-circuit configuration that we examine, our phase error is approximately 7.03° at 50 GHz. We study the sensitivity of the oscilloscope's phase response to parametric changes in sampling-circuit component values. We develop procedures to quantify the sensitivity of the phase error to each component and to a combination of components that depend on the fractional uncertainty in each of the model parameters as the same value, ±10%. We predict the upper and lower bounds of phase error, that is, we vary all of the circuit parameters simultaneously in such a way as to increase the phase error, and then vary all of the circuit parameters to decrease the phase error. Based on Type B evaluation, this method qualifies the impresses of all parameters of the sampling circuit and gives the value of standard uncertainty, 1.34°. This result is developed at the first time and has important practical uses. It can be used for phase calibration in the 50 GHz bandwidth large signal network analyzers (LSNAs). | ZHANG Zhe LIN MaoLiu XU QingHua TAN JiuBin | 2007 | Science in China(Series F)2007，50，6： | 1 |
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