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| 1 | In vivo theranostics with near-infraredemitting carbon dots—highly efficient photothermal therapy based on passive targeting after intravenous administration显示文摘Carbon dots that exhibit near-infrared fluorescence(NIR CDs)are considered emerging nanomaterials for advanced biomedical applications with low toxicity and superior photostability and targeting compared to currently used photoluminescence agents.Despite progress in the synthesis of NIR CDs,there remains a key obstacle to using them as an in vivo theranostic agent.This work demonstrates that the newly developed sulfur and nitrogen codoped NIR CDs are highly efficient in photothermal therapy(PTT)in mouse models(conversion efficiency of 59%)and can be readily visualized by photoluminescence and photoacoustic imaging.The real theranostic potential of NIR CDs is enhanced by their unique biodistribution and targeting.Contrary to all other nanomaterials that have been tested in biomedicine,they are excreted through the body’s renal filtration system.Moreover,after intravenous injection,NIR CDs are accumulated in tumor tissue via passive targeting,without any active species such as antibodies.Due to their accumulation in tumor tissue without the need for intratumor injection,high photothermal conversion,excellent optical and photoacoustic imaging performance,and renal excretion,the developed CDs are suitable for transfer to clinical biomedical practice. | Xin Bao Ye Yuan Jingqin Chen Bohan Zhang Di Li Ding Zhou Pengtao Jing Guiying Xu Yingli Wang Kateřina Holá Dezhen Shen Changfeng Wu Liang Song Chengbo Liu Radek Zbořil Songnan Qu | 2018 | Light(Science & Applications)2018,7,1: | 13 |
| 2 | Geochronology, Geochemistry and Tectonic Significance of the Early Carboniferous Gabbro and Diorite Plutons in West Ujimqin, Inner Mongolia显示文摘Early Carboniferous gabbros and diorites are distributed in West Ujimqin, Inner Mongolia. The LA-ICP-MS zircon U-Pb ages of the gabbro and diorite samples are 321± 2 Ma(MSWD=0.65) and 319.4± 1.5 Ma(MSWD=0.42), respectively. In addition, new geochemistry data from three gabbro and three diorite samples are presented. All six samples show high Al_2O_3 contents but low-TiO_2 contents, belonging to tholeiitic and calc-alkali basalt series. All of the samples have similar chondrite normalized REE patterns characterized by moderate depletion in LREE similar to normal middle oceanic ridge basalt(MORB). The MORB and PM-normalized trace element patterns show the enrichment in large ion lithophile elements(LILE, e.g., Rb, Ba and Sr), depletion in high field strength elements(HFSE) and distinctly negative Nb and Ta anomalies similar to volcanic arc basalt. Furthermore, as shown in the correlation plots of La/Ba vs. La/Nb, Ba/La vs. Ce/Pb, Th/La vs. Ce/Pb, Nb/La vs. Ba/Rb, and Nb/Y vs. La/Yb, the magma source has underwent contamination and metasomatism from the subduction fluid. According to the Zr/Nb, La/Nb, and La/Ta ratios and the Nb/Y vs. Zr/Y and Sm/Yb vs. La/Sm diagrams, the magma was derived from shallow depleted lithospheric mantle and formed by moderate(5%~20%) partial melting of spinel lherzolites. Tectonic setting discrimination diagrams reveal that the gabbros and diorites display both characteristics of MORB and volcanic arc basalt, which is consistent with their geochemical characteristics. On the basis of the geochemical features of these samples, combined with regional geological data and many previous researches in the study area, the Early Carboniferous gabbros and diorites of West Ujimqin are suggested to be formed in an intensely extensional rift setting, and a limited immature ocean basin probably formed after subsequent development. | Shiwei Ma Changfeng Liu Zhiqin Xu Zhiguang Zhou Jinyuan Dong Hongying Li | 2017 | Journal of Earth Science2017,28,2: | 10 |
| 3 | Heat transfer enhancement in the tube fitted with Left–Right helical blade rotors显示文摘 | Zhen Zhang Hua Yan Weimin Yang Yinpeng Zhou Yumei Ding Changfeng Guan | 2013 | Applied Thermal Engineering (-)2013,,1: | 4 |
| 4 | The complete genome of hydrocarbon-degrading Pseudoalteromonas sp. NJ289 and its phylogenetic relationship显示文摘Genus Pseudoalteromonas belongs to Family Pseudoalteromonadaceae in Gammaproteobacteria. A cold-adapted gram-negative bacterium, hydrocarbon-degrading Pseudoalteromonas sp. NJ289, was isolated from sea-ice of the Antarctica region, and sequenced the whole genome through the next generation sequencing platform. The assembly yielded three contigs representing two chromosomes and one plasmid with the sizes of 3.2 Mb, 636 kb and 1.8 kb, respectively. The G+C contents of genome were 40.83% and included 3 589 ORFs. Functional annotation indicated some potential roles in enzymatic activity and environmental adaptability. This study may help for understanding the population diverse, evolutionary ecology and the microbial interaction. | LIU Fangming WANG Yibin QU Changfeng ZHENG Zhou MIAO Jinlai XU Hua XIAO Tian | 2017 | Acta Oceanologica Sinica2017,36,2: | 2 |
| 5 | Rice(Oryza sativa L.)seedlings enriched with zinc or manganese:Their impacts on cadmium accumulation and expression of related genes显示文摘Cadmium(Cd)contamination in paddy soils means that the rice produced there may be unsafe for human consumption.A hydroponic study was conducted to enrich rice seedlings with zinc(Zn)or manganese(Mn),and the uptake and transport characteristics of Cd in these Zn-and Mn-rich seedlings were subsequently investigated using a greenhouse pot trial.The results showed that hydroponic cultivation in 10-50μmol L^(-1) Zn(ZnSO_(4)·7 H_(2)O)or50-250μmol L^(-1) Mn(MnSO_(4)·H_(2)O)for 30 d had no significant impact on rice growth,while the accumulation of Zn and Mn was 7.31-18.5 and 25.4-47.7 times higher,respectively,than in the control(no Zn or Mn addition).The accumulation of Cd in the Zn-and Mn-rich rice plants was 26.3%-38.6% and 34.4%-44.5% lower than that in the control,respectively,and the translocation factors of Cd from roots to shoots also decreased by 23.3%-41.3% and 25.3%-37.0%,respectively,after transplanting to Cd-contaminated soils.Furthermore,the relative expression levels of OsIRT1(Oryza sativa iron-regulated transporter 1)were downregulated by 40.1%-59.3% and 16.0%-25.9%,respectively,in the Zn-and Mn-rich seedling roots.This downregulation may indicate a possible mechanism contributing to the reductions in Cd absorption.Field experiments confirmed that the Zn-and Mn-rich seedlings produced brown rice(unpolished rice grains)with significantly decreased concentrations of Cd(34.2%-44.4%).This study provides an innovative method for reducing the food safety risks from rice grown on slightly to moderately Cd-contaminated paddy soils. | Gaoxiang HUANG Changfeng DING Yibing MA Yurong WANG Zhigao ZHOU Shun'an ZHENG Xingxiang WANG | 2021 | Pedosphere2021,31,6: | 2 |
| 6 | Carboniferous ridge subduction in the Xingmeng Orogenic Belt:Constraints from geochronological,geochemical,and Sr-Nd-Hf isotopic analysis of strongly peraluminous granites and gabbro-diorites in the Xilinhot micro-continent显示文摘The Xingmeng Orogenic Belt evolved through a long-lived orogeny involving multiple episodes of subduction and accretion.However,there is a debate on its tectonic evolution during the Late Paleozoic.Here,we report geochemical,geochronological,and isotopic data from strongly peraluminous granites and gabbro-diorites from the Sunidzuoqi-Xilinhot region.Zircon U-Pb ages suggest that the intrusive rocks were emplaced during the Early Carboniferous(333-322 Ma).The granites exhibit geochemical characteristics similar to S-type granites,with high SiO_(2)(72.34-76.53 wt.%),Al_(2)O_(3)(12.45-14.65 wt.%),and A/CNK(1.07-1.16),but depleted Sr,Nb,and Ta contents.They exhibit positiveε_(Nd)(t)andε_(Hf)(t)values(-0.3 to 2.8 and 2.7-5.7,respectively)and young Nd and Hf model ages(T_(DM2)(Nd)=853-1110 Ma and T_(DM2)(Hf)=975-1184 Ma),suggesting that they may be the partial melting products of heterogeneous sources with variable proportions of pelite,psammite,and metabasaltic rocks.The meta-gabbro-diorites from the Maihantaolegai pluton have low SiO_(2)(47.06-53.49 wt.%)and K_2O(0.04-0.99 wt.%)contents,and demonstrate slight light rare earth element(REE)depletion in the chondritenormalized REE diagrams.They have high zirconε_(Hf)(t)values(14.41-17.34)and young Hf model ages(T_(DM2)(Hf)=230-418 Ma),indicating a more depleted mantle source.The variations of the Sm/Yb and La/Sm ratios can thus be used to assess the melting degree of the mantle source from 5%to 20%,suggesting a quite shallow mantle melting zone.We propose that the petrogenesis and distribution of the strongly peraluminous granites and gabbro-diorites,as well as the tectonic architecture of the region,can be explained by a ridge subduction model.Based on these results,and previous studies,we suggest a southward ridge subduction model for the Sunidzuoqi-Xilinhot region. | Changfeng Liu Zhiguang Zhou Guosheng Wang Chen Wu Hongying Li Shiwei Ma | 2021 | Geoscience Frontiers2021,12,3: | 2 |
| 7 | Effects of Kallistatin on Oxidative Stress and Inflammation on Renal Ischemia-Reperfusion Injury in Mice显示文摘 | Shuqin Zhou Yingying Sun Yugang Zhuang Wei Zhao Yuanzhuo Chen Bojie Jiang Changfeng Guo Zhonglin Zhang Hu Peng Yanqing Chen | 2015 | Current Vascular Pharmacology2015,,2: | 1 |
| 8 | Coupling non-isothermal trickle-bed reactor with catalyst pellet models to understand the reaction and diffusion in gas oil hydrodesulfurization显示文摘In this work,a trickle-bed reactor coupled with catalyst pellet model is employed to understand the effects of the temperature and catalyst pellet structures on the reaction-diffusion behaviors in gas oil hydrodesulfurization(HDS).The non-isothermal reactor model is determined to be reasonable due to non-negligible temperature variation caused by the reaction heat.The reaction rate along the reactor is mainly dominated by the temperature,and the sulfur concentration gradient in the catalyst pellet decreases gradually along the reactor,leading to the increased internal effectiveness factor.For the fixed catalyst bed volume,there exists a compromise between the catalyst reaction rate and effectiveness factor.Under commonly studied catalyst pellet size of 0.8-3 mm and porosity of 0.4-0.8,an optimization of the temperature and catalyst pellet structures is carried out,and the optimized outlet sulfur content decreases to 7.6 wppm better than the commercial level at 0.96 mm of the catalyst pellet size and 0.40 of the catalyst porosity. | Xingqiang Zhao Changfeng Yang Mengke Lu Yao Shi Gang Qian Xinggui Zhou Xuezhi Duan | 2020 | Chinese Journal of Chemical Engineering2020,28,4: | 1 |
| 9 | The effect of the partial pressure of H 2 S on the permeation of hydrogen in low carbon pipeline steel显示文摘 | Chengshuang Zhou Shuqi Zheng Changfeng Chen Guiwu Lu | 2013 | Corrosion Science2013,,: | 1 |
| 10 | Identification and Expression Profile of a Neuropeptide LFRFamide-Like Gene During Different Stages of Gonadal Development in the Cephalopod Sepia pharaonis显示文摘Neuropeptides are widely distributed in vertebrates and invertebrates,regulating a variety of physiological activities in the organisms,such as metabolism,feeding and reproduction.In this study,to explore the function of neuropeptide LFRFamide in Sepia pharaonis,the full-length cDNA of LFRFamide-like gene(named SpLFRFL,MG869822.1)was identified with rapid amplification of cDNA ends(RACE)method.The sequence of SpLFRFL was 860 bp in length and encoded 188 amino acids containing 4 different mature peptides:1 copy of PHTPFRFamide,NSLFRFamide,TIFRFamide,and 3 copies of GNLFRFamide.Multiple alignment and phylogenetic analysis results showed that SpLFRFL shared high identity with LFRFamides of Sepia officinalis and Sepiella japonica and had the closest relationship with them.Through quantitative Real-time PCR(qRT-PCR),it was found that the SpLFRFL gene was highly expressed in the optic lobe and brain at three different stages during gonad development in both genders.Moreover,the four mature peptides at a concentration of 0.01μmol L^(−1) could inhibit the protein synthesis in the Chinese hamster ovary cell strain-K1(CHOK1)induced by SpGnRH.These data suggest that SpLFRFL might be involved in the development and reproduction of S.pharaonis.The results can contribute to future studies on neuropeptide evolution and function and benefit the cuttlefish farming. | QIU Jiayin SUN Lianlian LI Shuang ZHOU Xu CHI Changfeng ZHENG Libing | 2024 | Journal of Ocean University of China2024,23,2: | 0 |
| 11 | Geochemistry of the Mesoproterozoic Intrusions, Geochronology and Isotopic Constraints on the Xiaonanshan Cu-Ni Deposit along the Northern Margin of the North China Craton显示文摘Mesoproterozoic magma events in the Bayan Obo rift belt have remained poorly constrained and as a result, the Late Paleoproterozoic–Mesoproterozoic tectonic evolution of the rift belt has remained unclear. By a multiple-facetted regional geological investigation of this belt, we have resolved the stratigraphic sequence and geochronology of the Bayan Obo Group and made new discoveries including a three-stage mantle-derived magmatic sequence. Zircon and baddeleyite dating of Xiaonanshan hornblende pyroxenite emplaced into the Bayan Obo Group yields 207Pb/206Pb ages of ca. 1.34 and 1.33 Ga. The geochronological, geochemistry, Hf isotopic analyses place an important constraint on ages of the Late Paleoproterozoic–Mesoproterozoic strata and the evolution of the rift belt. Our field observations and U-Pb dating results suggest that mineralization is genetically related to Mesoproterozoic magmatism in North China Craton, i.e., 1.33–1.34 Ga. The δ34SV-CDT values of sulphide from the ore-bearing ultra-/mafic samples are about 6.2‰, whereas the 206Pb/204Pb, 207Pb/204Pb, and 208Pb/204Pb values vary in the ranges of 17.598–18.115, 15.496–15.501, and 37.478–37.952, respectively. The Late Paleozoic mafic gabbro and acidic granite porphyry intrusions are possible to bimodal magmatic event related to the extensional tectonic setting of the Central Asia in this period. | Zhiguang Zhou Jiangwei Yi Niu Guosheng Wang Chen Wu Changfeng Liu Juncheng Ju | 2020 | Journal of Earth Science2020,31,4: | 0 |
| 12 | Prediction Research on Ride Comfort of Special Full Trailer used by Precision Equipment显示文摘In order to evaluate a full trailer’s vibration performance,lumped mass model of seven degrees of freedom is set up to predict the ride comfort of whole vehicle.The acceleration history and the transfer function of each measuring point can be got from simulation.The analysis results show that the maximum acceleration RMS value of the vehicle mass center is about 0.3g,which satisfies the requirements of attenuating vibration of precision equipment being transported on particular roads and speeds.So the research provides valuable reference for the optimum selection of the suspension system’s parameters. | Zhou Changfeng Li Fengying Yao Zhenmin Lu Fangqing | 2013 | 仪器仪表学报2013,34,S1: | 0 |
| 13 | Miscibility of light oil and flue gas under thermal action显示文摘The miscibility of flue gas and different types of light oils is investigated through slender-tube miscible displacement experiment at high temperature and high pressure.Under the conditions of high temperature and high pressure,the miscible displacement of flue gas and light oil is possible.At the same temperature,there is a linear relationship between oil displacement efficiency and pressure.At the same pressure,the oil displacement efficiency increases gently and then rapidly to more than 90% to achieve miscible displacement with the increase of temperature.The rapid increase of oil displacement efficiency is closely related to the process that the light components of oil transit in phase state due to distillation with the rise of temperature.Moreover,at the same pressure,the lighter the oil,the lower the minimum miscibility temperature between flue gas and oil,which allows easier miscibility and ultimately better performance of thermal miscible flooding by air injection.The miscibility between flue gas and light oil at high temperature and high pressure is more typically characterized by phase transition at high temperature in supercritical state,and it is different from the contact extraction miscibility of CO_(2) under conventional high pressure conditions. | XI Changfeng WANG Bojun ZHAO Fang HUA Daode QI Zongyao LIU Tong ZHAO Zeqi TANG Junshi ZHOU You WANG Hongzhuang | 2024 | Petroleum Exploration and Development2024,51,1: | 0 |
| 14 | Effect of Aging Temperature on Stress Corrosion Cracking of 17-4 PH Stainless Steel in Wet H_2S Environment显示文摘The effect of aging temperature on stress corrosion crocking of 17-4 precipitation-hardened(PH)stainless steel in simulated stimulant oil well environment was studied by the method B-NACE standard bent-beam test.It is found that when aging temperature ranges from 480 to 610℃,the sensitivity of hydrogen embrittlement decreases significantly. | Zhou Chengshuang,Zheng Shuqi,Chen Changfeng,Lu Guiwu China University of Petroleum,Beijing 102249,China | 2012 | 稀有金属材料与工程2012,41,S1: | 0 |
| 15 | XPS Analysis of the Passive Film Formed on 825 Nickel Based Alloy Lined Pipe显示文摘The compositions and structures of the passive films formed on 825 nickel base alloy lined pipe serving for one year in an actual corrosion environment including 2.0 MPa H2S and 1.5 MPa CO2 at a temperature of 55℃were investigated by X-ray photoelectron spectroscopy(XPS).The results show that the passive films formed on 825 nickel base alloy is not destroyed even thicker than air-formed one and the films are composed of multilayer with different composition in each layer:an external part composed of a mixture of Cr and Ni oxide(more Ni included)and an inner part composed of a mixture of Cr and Ni oxide(Cr-rich layer). | Zheng Shuqi Chen Changfeng Zhou Chengshuang | 2012 | 稀有金属材料与工程2012,41,S1: | 0 |
| 16 | A review:crystalline silicon membranes over sealed cavities for pressure sensors by using silicon migration technology显示文摘A silicon pressure sensor is one of the very first MEMS components appearing in the microsystem area.The market for the MEMS pressure sensor is rapidly growing due to consumer electronic applications in recent years. Requirements of the pressure sensors with low cost, low power consumption and high accuracy drive one to develop a novel technology. This paper first overviews the historical development of the absolute pressure sensor briefly. It then reviews the state of the art technology for fabricating crystalline silicon membranes over sealed cavities by using the silicon migration technology in detail. By using only one lithographic step, the membranes defined in lateral and vertical dimensions can be realized by the technology. Finally, applications of MEMS through using the silicon migration technology are summarized. | Jiale Su Xinwei Zhang Guoping Zhou Changfeng Xia Wuqing Zhou Qing'an Huang | 2018 | Journal of Semiconductors2018,39,7: | 0 |
| 17 | Catalyst particle shapes and pore structure engineering for hydrodesulfurization and hydrodenitrogenation reactions显示文摘Catalyst particle shapes and pore structure engineering are crucial for alleviating internal diffusion limitations in the hydrodesulfiirization(HDS)/hydrodeni-trogenation(HDN)of gas oil.The effects of catalyst particle shapes(sphere,cylinder,trilobe,and tetralobe)and pore structures(pore diameter and porosity)on HDS/HDN performance at the particle scale are investigated via mathematical modeling.The relationship between particle shape and effectiveness factor is first established,and the specific surface areas of different catalyst particles show a positive correlation with the average HDS/HDN reaction rates.The catalyst particle shapes primarily alter the average HDS/HDN reaction rate to adjust the HDS/HDN effectiveness factor.An optimal average HDS/HDN reaction rate exists as the catalyst pore diameter and porosity increase,and this optimum value indicates a tradeoff between diffusion and reaction.In contrast to catalyst particle shapes,the catalyst pore diameter and the porosity of catalyst particles primarily alter the surface HDS/HDN reaction rate to adjust the HDS/HDN effectiveness factor.This study provides insights into the engineering of catalyst particle shapes and pore structures for improving HDS/HDN catalyst particle efficiency. | Yao Shi Zhao Li Changfeng Yang Zhanlin Yang Zhenhui Lv Chong Peng Bao-Lian Su Weikang Yuan Xinggui Zhou Xuezhi Duan | 2022 | Frontiers of Chemical Science and Engineering2022,16,6: | 0 |
| 18 | A PIID-DTBT based semi-conducting polymer dots with broad and strong optical absorption in the visible-light region: Highly effective contrast agents for multiscale and multi-spectral photoacoustic imaging显示文摘作为一种混合成像技术, photoacoustic 成像(白族) 能提供纸巾的多尺度的词法信息,并且多光谱的白族(MSPAI ) 的使用能恢复兴趣的色基的空间分发,例如在纸巾以内的血红素。此处,我们开发了能很有效地为复杂生物纸巾的更全面的描述把多尺度的白族与 MSPAI 相结合的一个对比代理人。明确地,我们开发了新奇 PIID-DTBT 在可见光的区域(500-700 nm ) 显示出宽广、强壮的光吸收的基于的半导体的聚合物点(Pdots ) 。金 nanoparticles (GNP ) 和金 nanorods (GNR ) 的表演,作为优秀 photoacoustic 对比代理人被验证了,基于多尺度的白族系统与 Pdots 的相比。两前 vivo 并且在 vivo,实验比有在在一样的 700 nm 的 GNR 的 GNP 和显示出的类似的 photoacoustic 性能集中的证明 Pdots 在 532 nm 有更好的 photoacoustic 变换效率集中。Photostability 和毒性测试证明 Pdots 是 photostable 和 biocompatible。更重要地,一在里面 vivo MSPAI 实验显示 Pdots 比血有更好的 photoacoustic 性能,因此,信号能精确地从脉管富人的纸巾的背景被提取。我们的工作基于多尺度的白族和 MSPAI 相对血容器为损害的精确本地化作为高度有效的对比代理人表明 Pdots 的大潜力。 | Jian Zhang Haobin Chen Ting Zhou Limei Wang Duyang Gao Xuanjun Zhang Yubin Liu Changfeng Wu Zhen Yuan | 2017 | Nano Research2017,10,1: | 0 |