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| 1 | Prevalence of Autism Spectrum Disorder in China:A Nationwide Multi-center Population-based Study Among Children Aged 6 to 12 Years显示文摘This study aimed to obtain the first national estimate of the prevalence of autism spectrum disorder(ASD) in Chinese children.We targeted the population of 6 to 12-year-old children for this prevalence study by multistage convenient cluster sampling.The Modified Chinese Autism Spectrum Rating Scale was used for the screening process.Of the target population of 142,086 children,88.5%(n=125,806) participated in the study.A total of 363 children were confirmed as having ASD.The observed ASD prevalence rate was 0.29%(95% CI:0.26%-0.32%) for the overall population.After adjustment for response rates,the estimated number of ASD cases was867 in the target population sample,thereby achieving an estimated prevalence of 0.70%(95% CI:0.64%-0.74%).The prevalence was significantly higher in boys than in girls(0.95%;95% CI:0.87%-1.02% versus 0.30%;95%CI:0.26%-0.34%;P <0.001).Of the 363 confirmed ASD cases,43.3% were newly diagnosed,and most of those(90.4%) were attending regular schools,and 68.8% of the children with ASD had at least one neuropsychiatric comorbidity.Our findings provide reliable data on the estimated ASD prevalence and comorbidities in Chinese children. | Hao Zhou Xiu Xu Weili Yan Xiaobing Zou Lijie Wu Xuerong Luo Tingyu Li Yi Huang Hongyan Guan Xiang Chen Meng Mao Kun Xia Lan Zhang Erzhen Li Xiaoling Ge Lili Zhang Chunpei Li Xudong Zhang Yuanfeng Zhou Ding Ding Andy Shih Eric Fombonne Yi Zheng Jisheng Han Zhongsheng Sun Yong-hui Jiang Yi Wang LATENT-NHC Study Team | 2020 | Neuroscience Bulletin2020,36,9: | 158 |
| 2 | Anisotropic coding metamaterials and their powerful manipulation of differently polarized terahertz waves显示文摘Metamaterials based on effective media can be used to produce a number of unusual physical properties(for example,negative refraction and invisibility cloaking)because they can be tailored with effective medium parameters that do not occur in nature.Recently,the use of coding metamaterials has been suggested for the control of electromagnetic waves through the design of coding sequences using digital elements‘0’and‘1,'which possess opposite phase responses.Here we propose the concept of an anisotropic coding metamaterial in which the coding behaviors in different directions are dependent on the polarization status of the electromagnetic waves.We experimentally demonstrate an ultrathin and flexible polarization-controlled anisotropic coding metasurface that functions in the terahertz regime using specially designed coding elements.By encoding the elements with elaborately designed coding sequences(both 1-bit and 2-bit sequences),the x-and y-polarized waves can be anomalously reflected or independently diffused in three dimensions.The simulated far-field scattering patterns and near-field distributions are presented to illustrate the dual-functional performance of the encoded metasurface,and the results are consistent with the measured results.We further demonstrate the ability of the anisotropic coding metasurfaces to generate a beam splitter and realize simultaneous anomalous reflections and polarization conversions,thus providing powerful control of differently polarized electromagnetic waves.The proposed method enables versatile beam behaviors under orthogonal polarizations using a single metasurface and has the potential for use in the development of interesting terahertz devices. | Shuo Liu Tie Jun Cui Quan Xu Di Bao Liangliang Du Xiang Wan Wen Xuan Tang Chunmei Ouyang Xiao Yang Zhou Hao Yuan Hui Feng Ma Wei Xiang Jiang Jiaguang Han Weili Zhang Qiang Cheng | 2016 | Light(Science & Applications)2016,5,1: | 36 |
| 3 | Autotrophic denitrification for nitrate and nitrite removal using sulfur-limestone显示文摘Sulfur-limestone was used in the autotrophic denitrification process to remove the nitrate and nitrite in a lab scale upflow biofilter.Synthetic water with four levels of nitrate and nitrite concentrations of 10,40,70 and 100 mg N/L was tested.When treating the low concentration of nitrate-or nitrite-contaminated water(10,40 mg N/L),a high removal rate of about 90% was achieved at the hydraulic retention time(HRT) of 3 hr and temperature of 20-25°C.At the same HRT,50% of the nitrate or nitrite could be removed even at the low temperature of 5-10°C.For the higher concentration nitrate and nitrite(70,100 mg N/L),longer HRT was required.The batch test indicated that influent concentration,HRT and temperature are important factors afiecting the denitrification eficiency.Molecular analysis implied that nitrate and nitrite were denitrified into nitrogen by the same microorganisms.The sequential two-step-reactions from nitrate to nitrite and from nitrite to the next-step product might have taken place in the same cell during the autotrophic denitrification process. | Weili Zhou Yejue Sun Bingtao Wu Yue Zhang Min Huang Toshiaki Miyanaga Zhenjia Zhang | 2011 | Journal of Environmental Sciences2011,23,11: | 34 |
| 4 | Sulfur-based autotrophic denitrification from the micro-polluted water显示文摘Eutrophication caused by high concentrations of nutrients is a huge problem for many natural lakes and reservoirs. Removing the nitrogen contamination from the low C/N water body has become an urgent need. Autotrophic denitrification with the sulfur compound as electron donor was investigated in the biofilter reactors. Through the lab-scale experiment,it was found that different sulfur compounds and different carriers caused very different treatment performances. Thiosulfate was selected to be the best electron donor and ceramsite was chosen as the suitable carrier due to the good denitrification efficiency, low cost and the good resistibility against the high hydraulic loads. Later the optimum running parameters of the process were determined. Then the pilot-scale experiment was carried out with the real micro-polluted water from the West Lake, China. The results indicated that the autotrophic denitrification with thiosulfate as electron donor was feasible and applicable for the micro-polluted lake water. | Weili Zhou Xu Liu Xiaojing Dong Zheng Wang Ying Yuan Hui Wang Shengbing He | 2016 | Journal of Environmental Sciences2016,28,6: | 18 |
| 5 | MiR-139-5p inhibits migration and invasion of colorectal cancer by downregulating AMFR and NOTCH1显示文摘MicroRNAs (miRNAs ) 由抑制最近在 carcinogenesis 和转移在我们 non-protein-coding RNA 的角色的理解带给卓见的 posttranscriptional 施加功能。在这研究,我们在 CRC 在 colorectal 癌症(CRC ) 和它的潜在的临床的应用程序描述了函数和 miR-139-5p 的分子的机制。我们发现 miR-139-5p 是显著地, CRC 与邻近的 noncancerous 纸巾(NCT ) 相比取样的在 73.8% 的 downregulated,和减少的 miR-139-5p 与穷人被联系预后。功能的分析证明 miR-139-5p 的那个宫外的表达式在 vivo 在 vitro 和转移压制了 CRC 房间移植和侵略。机械学的调查表明 miR-139-5p 由指向 AMFR 和 NOTCH1 压制 CRC 房间侵略和转移。二基因 phenocopied 击倒 CRC 上的 miR-139-5p 的禁止的效果转移。而且,二基因的蛋白质层次与 NCT 相比是在 CRC 样品的 upregulated,并且相反地与 miR-139-5p 表示相关。增加的 NOTCH1 蛋白质表示与 CRC 病人的差的预后被相关。一起,我们的数据显示 miR-139-5p 为 CRC 是潜在的肿瘤 suppressor 和预示的因素,并且指向 miR-139-5p 可以镇压 CRC 的转移并且改善幸存。 | Mingxu Song Yuan Yin Jiwei Zhang Binbin Zhang Zehua Bian Chao Quan Leyuan Zhou Yaling Hu Qifeng Wang Shujuan Ni Bojian Fei Weili Wang Xiang Du Dong Hua Zhaohui Huang | 2014 | Protein & Cell2014,5,11: | 14 |
| 6 | Modifying the Autism Spectrum Rating Scale(6–18 years)to a Chinese Context:An Exploratory Factor Analysis显示文摘The purpose of this study was to explore the psychometric properties of the Chinese version of the autism spectrum rating scale(ASRS). We recruited 1,625community-based children and 211 autism spectrum disorder(ASD) cases from 4 sites, and the parents of all participants completed the Chinese version of the ASRS. A robust weighted least squares means and variance adjusted estimator was used for exploratory factor analysis. The3-factor structure included 59 items suitable for the current sample. The item reliability for the modi?ed Chinese version of the ASRS(MC-ASRS) was excellent. Moreover,with 60 as the cut-off point, receiver operating characteristic analysis showed that the MC-ASRS had excellent discriminate validity, comparable to that of the unmodi?ed Chinese version(UC-ASRS), with area under the curve values of 0.952(95% CI: 0.936–0.967) and 0.948(95% CI:0.930–0.965), respectively. Meanwhile, the con?rm factor analysis revealed that MC-ASRS had a better construct validity than UC-ASRS based on the above factor solution in another children sample. In conclusion, the MC-ASRS shows better ef?cacy in epidemiological screening for ASD in Chinese children. | Hao Zhou Lili Zhang Xuerong Luo Lijie Wu Xiaobing Zou Kun Xia Yimin Wang Xiu Xu Xiaoling Ge Yong-Hui Jiang Eric Fombonne Weili Yan Yi Wang | 2017 | Neuroscience Bulletin2017,33,2: | 8 |
| 7 | Influence of Temperature and Salinity on Germination of Eelgrass (Zostera marina L.) Seeds显示文摘Seagrass restoration as part of ocean ecosystem protection has been launched for many years all over the world, but intensive research on this subject in China has just begun in recent years. Seed broadcasting has been widely accepted as the most potentially useful method for seagrass restoration over large areas. We examined the influence of key environmental factors on seed germination to help promote eelgrass bed restoration. Under anoxic conditions, the influence of temperature and salinity on the germination rate of eelgrass (Zostera marina L.) seeds was examined at different combinations of four temperatures (4, 9, 14, and 24℃) and nine salinities (5 to 45, increment of 5). The effect of significant interaction of temperature and salinity on germination rate was observed (ANOVA) (P<0.001). The highest germination rate (83.3 ± 3.5)% was reached in 8 weeks at 14℃ and salinity 5. Higher temperature significantly increased the germination rate at salinity 5 (P<0.001) during the whole observation period except for 24℃, while lower salinity significantly increased the germination rate at 14℃ (P<0.001). Although significant interaction was found between temperature and salinity (P<0.001), the influence of salinity was stronger than that of temperature for the germination of eelgrass seeds. These results provide useful information for the propagation of artificial seedlings for seagrass restoration in China. | PAN Jinhua JIANG Xin LI Xiaojie CONG Yizhou ZHANG Zhuangzhi LI Zhiling ZHOU Weili HAN Houwei LUO Shiju YANG Guanpin | 2011 | Journal of Ocean University of China2011,10,2: | 7 |
| 8 | Sedimentation Rate Rhythms:Evidence from Filling of the Tarim Basin,Northwest China显示文摘Variations of sedimentation rate within a basin over geologic time are a time series that can be filtered into several cyclic wave curves. Based on back-stripping and the empirical mode decomposition method, the cores from 14 wells in the Tarim Basin were selected to do filtering analysis. Four cycles or quasi-cycles(33 Ma, 64.4 Ma, 103.6 Ma, and 224 Ma) were obtained. Among these, the 33 Ma period, which was related to the internal earth activity, an external force, or a combination of the two, was the most obvious. The 64.4 Ma period corresponded to the solar system crossing the galaxy plane or the periodic melting of inner-earth material. The 103.6 Ma period was related with plate collisional tectonism around the Tarim Plate. The 224 Ma period was related to one galaxy year and may also be related to the aesthenospherical convection cycle. | CHEN Shuping JIN Zhijun WANG Yi ZHOU Ziyong LI Jingchang YANG Weili | 2015 | Acta Geologica Sinica(English Edition)2015,89,4: | 6 |
| 9 | Performance of the Autism Spectrum Rating Scale and Social Responsiveness Scale in Identifying Autism Spectrum Disorder Among Cases of Intellectual Disability显示文摘The Autism Spectrum Rating Scale(ASRS) and the Social Responsiveness Scale(SRS) have been widely used for screening autism spectrum disorder(ASD) in the general population during epidemiological studies, but studies of individuals with intellectual disability(ID) are quite limited. Therefore, we recruited the parents/caregivers of 204 ASD cases, 71 ID cases aged 6–18 years from special education schools, and 402 typically developing(TD) children in the same age span from a communitybased population to complete the ASRS and SRS. The results showed that the ID group scored significantly lower on total and subscale scores than the ASD group on both scales(P \ 0.05) but higher than TD children(P \ 0.05).Receiver operating characteristic analyses demonstrated a similar fair performance in discriminating ASD from ID with the ASRS(area under the curve(AUC) = 0.709,sensitivity = 77.0%, specificity = 52.1%, positive predictive value(PPV) = 82.2%) and the SRS(AUC = 0.742,sensitivity = 59.8%, specificity = 77.5%, PPV = 88.4%).The results showed that individuals with ID had clear autistic traits and discriminating ASD from ID cases was quite challenging, while assessment tools such as ASRS and SRS, help to some degree. | Chunpei Li Hao Zhou Tianqi Wang Shasha Long Xiaonan Du Xiu Xu Weili Yan Yi Wang | 2018 | Neuroscience Bulletin2018,34,6: | 5 |
| 10 | Integrated genomic analysis identifies deregulated JAK/STAT-MYC-biosynthesis axis in aggressive NK-cell leukemia显示文摘好攻击的 NK 房间白血病(ANKL ) 是在从亚洲的人之中是更流行的 NK 房间瘤的一种稀罕形式并且中央并且南美洲。病人们通常在天以内死到月,甚至在收到迅速的治疗学的管理以后。这里,我们由集成整个染色体执行了 ANKL 的第一全面研究, transcriptome 并且定序指向,象功能的试金一样的 cytokine 数组。在 JAK-STAT 小径的变化在 48% 被识别(14/29 ) ANKL 病人,当细胞外的 STAT3 激发器 IL10 被 56 褶层的一般水准提高时(P < 0.0001 ) 在检查的所有病人的血浆。另外的经常变异的基因包括的 TP53 (34%) , TET2 (28%) , CREBBP (21%) 和 MLL2 (21%) 。耐心的 NK 白血病房间在多重新陈代谢的小径显示出 STAT3 phosphorylation, MYC 表示和 transcriptional 活动的突出的激活。机能上地, STAT3 激活和 MYC 表示为 ANKL 房间的增长和幸存是批评的。发信号的 STAT 调整了发信号的 MYC 抄写节目,和两 STAT, MYC 抄写被要求维持核苷酸合成和 glycolysis 的激活。一起, JAK-STAT 小径在 ANKL 为 genomic 改变和 IL10 刺激代表一个主要目标。这最新发现的 JAK/STAT-MYC-biosynthesis 轴可以在对待白血病的这种子类型为新奇治疗学的策略的发展提供机会。 | Liang Huang Dan Liu Na Wang Shaoping Ling Yuting Tang Jun Wu Lingtong Hao Hui Luo Xuelian Hu Lingshuang Sheng Lijun Zhu Di Wang Yi Luo Zhen Shang Min Xiao Xia Mao Kuangguo Zhou Lihua Cao Lili Dong Xinchang Zheng Pinpin Sui Jianlin He Shanlan Mo Jin Yan Qilin Ao Lugui Qiu Hongsheng Zhou Qifa Liu Hongyu Zhang Jianyong Li Jie Jin Li Fu Weili Zhao Jieping Chen Xin Du Guoliang Qing Hudan Liu Xin Liu Gang Huang Ding Ma Jianfeng Zhou Qian-fei Wang | 2018 | Cell Research2018,28,2: | 5 |
| 11 | Chinese Norms for the Autism Spectrum Rating Scale显示文摘This study aimed to establish norms for the modi?ed Chinese version of the Autism Spectrum Rating Scale(ASRS). Participants were recruited from Shanghai,Harbin, Guangzhou, and Changsha, China, and their parents and teachers were invited to complete the Chinese Parent version and the Teacher version of the ASRS. In both versions, boys had signi?cantly higher sub-scale scores and total score(T-score) by 1–3 and 4–5 points respectively, than girls(both P \ 0.001). Age had weak correlations with some sub-scores and the T-score(r ranged from-0.1859 to 0.0738), and some reached signi?cance(P \ 0.03). The correlations appeared stronger and were more common in females. The T-score based on Chinese norms ideally correlated with the score based on the United States norms in boys and girls for both versions.Norms for the Chinese version of the ASRS for children aged 6–12 years are proposed and may be helpful for screening individuals with autism spectrum disorders from the general population of children. | Hao Zhou Lili Zhang Xiaobing Zou Xuerong Luo Kun Xia Lijie Wu Yimin Wang Xiu Xu Xiaoling Ge Yong-Hui Jiang Eric Fombonne Weili Yan Yi Wang | 2017 | Neuroscience Bulletin2017,33,2: | 5 |
| 12 | Assessing the Accuracy of the Modified Chinese Autism Spectrum Rating Scale and Social Responsiveness Scale for Screening Autism Spectrum Disorder in Chinese Children显示文摘The reported prevalence of autism spectrum disorder(ASD) has been increasing rapidly in many parts of the world. However, data on its prevalence in China are largely missing. Here, we assessed the suitability of the modi?ed Chinese version of a newly-developed ASD screening tool, the Modi?ed Chinese Autism Spectrum Rating Scales(MC-ASRS) in screening for ASD in Chi nese children aged 6–12 years, through comparison with the Social Responsiveness Scale(SRS) that has been widely used for ASD screening. We recruited the par ents/caregivers of 1588 typically-developing children and190 children with ASD aged 6–12 years to complete the MC-ASRS and SRS, and evaluated the validity of both scales in discriminating children with ASD from those developing typically. The results showed that MC-ASRSperformed as well as SRS in sensitivity, speci?city, and area-under-the-curve(both [0.95) in receiver operating characteristic analysis, with a fair false-negative rate.These results suggest that MC-ASRS is a promising tool for screening for children with ASD in the general Chinese population. | Bingrui Zhou Hao Zhou Lijie Wu Xiaobing Zou Xuerong Luo Eric Fombonne Yi Wang Weili Yan Xiu Xu | 2017 | Neuroscience Bulletin2017,33,2: | 5 |
| 13 | Improving Tribological Performance of Gray Cast Iron by Laser Peening in Dynamic Strain Aging Temperature Regime显示文摘A high and stable brake disc friction coefficient is needed for automobile safety, while the coefficient degrades due to elevated temperature during the braking process. There is no better solution except changes in material composition and shape design optimization. In the dynamic strain aging(DSA) temperature regime of gray cast iron, micro-dimples with different dimple depth over diameter and surface area density are fabricated on the material surface by laser peening(LP) which is an LST method. Friction behavior and wear mechanism are investigated to evaluate the effects of surface texturing on the tribological performance of specimens under dry conditions. Through LP impacts assisted by DSA, the friction coefficients of the LPed specimens increase noticeably both at room temperature and elevated temperature in comparison to untreated specimens. Moreover, the coefficient of specimen with dimple depth over diameter of 0.03 and surface area density of 30% is up to 0.351 at room temperature, which dramatically rises up to 1.33 times that of untextured specimen and the value is still up to 0.3305 at 400℃ with an increasing ratio of 35% compared to that of untreated specimen. The surface of textured specimen shows better wear resistance compared to untreated specimen. Wear mechanism includes adhesive wear, abrasive wear and oxidation wear. It is demonstrated that LP assisted by DSA can substantially improve wear resistance, raise the friction coefficient as well as its stability of gray cast iron under elevated temperatures. Heat fade and premature wear can be effectively relieved by this surface modification method. | FENG Xu ZHOU Jianzhong MEI Yufen HUANG Shu SHENG Jie ZHU Weili | 2015 | Chinese Journal of Mechanical Engineering2015,28,5: | 5 |
| 14 | Breast cancer-specific serum peptide profiles显示文摘Early detection of breast cancer is paramount to successful clinical therapy. Yet, early-stage breast cancer lacks specific symptoms or biomarkers. With the emerging of the mass spectrometric (MS) -based signatures as biomarkers, we investigated breast cancer-related serum profile pattern through class prediction and independent validation, and used Fourier transfer MS to identify breast cancer signature. We now show a distinctive serum peptide pattern that discriminates breast cancer from healthy controls with 93.2% sensitivity and 95.4% specificity. m/z 5901.70 and 4465.74 of ion fragment of FPA and alpha1-antichymotrypsin are found in the signatures that predominantly discriminate breast cancer from healthy individuals. These novel findings identify an MS-based serum peptide pattern of breast cancer that may have direct clinical utility in future. | WANG Na WEN XinYu WANG Jie LI AiLing LI WeiHua LI Tao Li Yan ZHANG XueMin WANG HongXia YANG SongCheng ZHOU Tao GONG WeiLi TIAN YaPing HE Kun | 2009 | Chinese Science Bulletin2009,54,3: | 4 |
| 15 | Optical rogue wave in random fiber laser显示文摘The famous demonstration of optical rogue waves(RWs),a powerful tool to reveal the fundamental physics in different laser scenarios,opened a flourishing time for temporal statistics.Random fiber laser(RFL)has likewise attracted wide attention due to its great potential in multidisciplinary demonstrations and promising applications.However,owing to the distinctive cavity-free structure,it is a scientific challenge to achieve temporal localized RWs in RFLs,whose feedback arises from multiple scattering in disordered medium.Here,we report the exploration of RW in the highly skewed,transient intensity of an incoherently pumped RFL for the first time,to our knowledge,and unfold the involved kinetics successfully.The corresponding frequency domain measurements demonstrate that the RW event arises from a crucial sustained stimulated Brillouin scattering process with intrinsic stochastic nature.This investigation highlights a novel path to fully understanding the complex physics,such as photon propagation and localization,in disordered media. | JIANGMING XU JIAN WU JUN YE JIAXIN SONG BAICHENG YAO HANWEI ZHANG JINYONG LENG WEILI ZHANG PU ZHOU YUNJIANG RAO | 2020 | Photonics Research2020,8,1: | 4 |
| 16 | 6.5 wt%Si high silicon steel sheets prepared by composite electrodeposition in magnetic field显示文摘A new preparation method of near-net-shape 6.5 wt% Si high silicon steel sheets was proposed by combining composite electrodeposition(CED) and diffusion annealing under magnetic field. The obtained sheets were characterized by scanning electron microscopy, energy dispersive spectrometry, analytical balance and a silicon steel material measurement system. The results show that the surface morphology,the elemental distribution, the cathode current efficiency and the silicon content of coatings were obviously influenced by the micro and macro magnetohydrodynamics(MHD) flows under magnetic field.With the effect of magnetic field, the silicon particles content of coatings showed an increasing trend and the diffusion process showed that an approximately uniform 6.5 wt% silicon steel sheet has been successfully obtained. The magnetism measurement showed that the high silicon steel sheet has the lower iron loss, and the iron loss further decreased under magnetic field. The new method proposed in this article,which is more environmentally friendly and low energy consumption, is feasible to prepare high silicon steel sheets. | Minghu Peng Yunbo Zhong Tianxiang Zheng Lijun Fan Junfeng Zhou Weili Ren Zhongming Ren | 2018 | Journal of Materials Science & Technology2018,34,12: | 3 |
| 17 | Reservoir accumulation conditions and key exploration&development technologies for Keshen gas field in Tarim Basin显示文摘The Keshen gas field is located in the central part of Kuqa foreland thrust belt in Tarim Basin,and is another large gas field discovered in Kuqa depression after Kela 2 gas field.Since the breakthrough in 2008,a number of large and medium scale gas reservoirs including Keshen 2,Keshen 5 and Keshen 8 have been discovered,that are characterized by ultra depth,ultra-high pressure,ultra-low porosity,ultra-low permeability,high temperature and high pressure.With natural gas geological reserves of nearly trillion cubic meters and production capacity of nearly 5.5 billion cubic meters,the Keshen gas field is the main natural gas producing area in Tarim Oilfield.The Keshen gas field is located in a series of thrusting imbrication structures in the Kelasu structural belt of Kuqa foreland thrust belt.The salt roof structure,plastic rheology of salt beds and pre-salt faulted anticlinal structure constitute the large wedge-shaped thrust body.The thick delta sandstone of the Cretaceous Bashijike Formation is widely distributed,and it forms the superior reservoir-caprock combination with overlying Paleogene thick gypsum-salt bed.The deep Jurassic-Triassic oil and gas migrate vertically along fault system formed in Late Himalaya,break through the thick Cretaceous mudstone and move laterally along the fracture system of the pre-salt reservoirs,to form anticline and fault anticline high pressure reservoir groups.Through near ten years of studies,the three-dimensional seismic acquisition and processing technology for complex mountainous areas,extrusion salt-related structural modeling technology and fractured low-porosity sandstone reservoir evaluation technology have been established,which lay a foundation for realization of oil and gas exploration objectives.Logging acquisition and evaluation technology for high temperature,high pressure,ultra-deep and low-porosity sandstone gas reservoirs,and efficient development technology for fractured tight sandstone gas reservoirs have been developed,which provide a technical support for efficient exploration&development and rapid production of the Keshen gas field. | Haijun Yang Yong Li Yangang Tang Ganglin Lei Xiongwei Sun Peng Zhou Lu Zhou Anming Xu Jingjie Tang Wenhui Zhu Jiangwei Shang Weili Chen Mei Li | 2019 | Petroleum Research2019,4,4: | 3 |
| 18 | Photothermally Responsive Conjugated Polymeric Singlet Oxygen Carrier for Phase Change-Controlled and Sustainable Phototherapy for Hypoxic Tumor显示文摘Hypoxia significantly compromises the therapeutic performance of photodynamic therapy(PDT)owing to the oxygen level which plays a key role in the production of singlet oxygen(^(1)O_(2)).Herein,the photothermally responsive phase change materials(PCM)are used to encapsulate 1,4-dimethylnaphthalene-functionalized platinum(II)-acetylide conjugated polymer(CP1)with intense nearinfrared(NIR)absorption to prepare new ^(1)O_(2) nanocarriers(CP1-NCs).The 1,4-dimethylnaphthalene moieties in CP1-NCs can trap the ^(1)O_(2) produced from CP1 under irradiation and form a stable endoperoxide.Then,the endoperoxide undergoes cycloreversion to controllably release ^(1)O_(2) via the NIR light-triggered photothermal effect of CP1 and controllable phase change of PCM,which can be used for oxygen-independent PDT for hypoxic tumor.Furthermore,the in vivo luminescence imagingguided synergistic PDT and photothermal therapy showed better efficiency in tumor ablation.The smart design shows the potent promise of CP1-NCs in PCM-controlled and sustainable phototherapy under tumor hypoxic microenvironment,providing new insights for constructing oxygen-independent precise cancer phototherapeutic platform. | Guo Li Ruyi Zhou Weili Zhao Bo Yu Jie Zhou Shujuan Liu Wei Huang Qiang Zhao | 2020 | Research2020,,1: | 3 |
| 19 | A study of peroxyacetyl nitrate at a rural site in Beijing based on continuous observations from 2015 to 2019 and the WRFChem model显示文摘Peroxyacetyl nitrate(PA N)is one of the most important photochemical pollutants and has aroused much concern in China in recent decades.However,few studies described the long-term variations in PAN in China.In this study,we continuously monitored the PAN,03 and NOx concentrations at a regional background site near Beijing from August 2015 to February 2019.Based on the observed concentrations and climate data,w e analyzed the seasonal PAN variations.The results revealed that the monthly mean PAN concentration ranged from 0.33-2.41 ppb,with an average value of 0.94 ppb.The PAN concentration exhibited a distinct seasonal variation,with high values in spring and low values in winter.After analyzing the corresponding meteorological data,we found that stronger ultraviolet(UV)radiation,a relatively longer lifetime and a higher background PAN concentration contributed to the high PAN concentrations in spring.In addition,with the utilization of the WRF-Chem(Weather Research and Forecasting with Chemistry)model,the cause of the extremely high PAN concentration in spring 2018 wa s determined.The model results demonstrated that an anomalously low pressure and the southwesterly winds in northern China might be the main causes of the increased PAN concentration in Beijing and its surrounding area in spring 2018. | Yulu Qiu Zhiqiang Ma Weili Lin Weijun Quan Weiwei Pu Yingruo Li Liyan Zhou Qingfeng Shi | 2020 | Frontiers of Environmental Science & Engineering2020,14,4: | 3 |
| 20 | Mesoporous iron oxide-silica supported gold catalysts for low-temperature CO oxidation显示文摘Mesoporous iron oxide-silica composite with a high silica content was synthesized by hydrothermal method,and another composite material with a high iron content was obtained by etching part of silica in alkaline solution.Gold catalysts were loaded onto both composites by a deposition-precipitation method,and used for CO oxidation.The samples were characterized by BrumauerEmmet-Teller(BET),X-ray diffraction(XRD),X-ray photoelectron spectra(XPS),transmission electron microscope(TEM)and scanning electron microscope(SEM)techniques.Both composites had high specific surface areas and were amorphous.The Au nanoparticles dispersed on the surface of the composites existed in metallic state.Composite with high silica content was not suitable for Au loading,and its supported gold catalyst showed poor performance in catalytic reaction.In contrast,composite with high iron content allowed efficient Au loading,and CO could be oxidized completely at low temperature on its supported gold catalyst.The effects of deposition-precipitation pH values on Au loading and activity of the catalyst were investigated,and the results indicated that Au loading was the highest and the catalyst was the most active for CO oxidation when the synthesis pH was adjusted to 8. | Weidong Zhang Xiaofei Lu Weili Zhou Feng Wu Jinjun Li | 2014 | Chinese Science Bulletin2014,59,31: | 3 |