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| 1 | In-situ observation for formation and dissociation of carbon dioxide hydrate in porous media by magnetic resonance imaging显示文摘The study of formation and dissociation of CO 2 hydrate in porous media was characterized by magnetic resonance imaging (MRI) system in in situ conditions. This work simulated porous media by using glass beads of uniform size. The growth and dissociation habit of CO2 hydrate was observed under different temperature and pressure conditions. The induction time and the hydrate saturation during the growth and dissociation process in different sizes of porous media were obtained by using the MRI signal intensity. The results indicate that hydrate growth rate and the induction time are affected by the size of porous media, pressure, and degree of supercooling. There are three hydrate growth stages, i.e., initial growth stage, rapid growth stage and steady stage. In this study,the CO2 hydrate forms preferentially at the surface of vessel and then gradually grows inward. The hydrate tends to cement the glass beads together and occupies the pore gradually. As the hydrate decomposes gradually, the dissociation rate increases to the maximum and then decreases to zero. | CHENG ChuanXiao ZHAO JiaFei SONG YongChen ZHU ZiHao LIU WeiGuo ZHANG Yi YANG MingJun YU XiChong | 2013 | Science China Earth Sciences2013,56,4: | 5 |
| 2 | Molecular cloning and functional identification of a cDNA encoding 4-hydroxy-3-methylbut-2-enyl diphosphate reductase from Tripterygium wilfordii显示文摘The 4-hydroxy-3-methylbut-2-enyl diphosphate reductase(HDR) is the last step key enzyme of the methylerythritol phosphate(MEP) pathway,synthesizing isopentenyl diphosphate and its allyl isomer dimethylallyl diphosphate,which is important for regulation of isoprenoid biosynthesis.Here the full-length cDNA of HDR,designated TwHDR(GenBank Accession No.KJ933412.1),was isolated from Tripterygium wilfordii for the first time.TwHDR has an open reading frame(ORF) of 1386 bp encoding461 amino acids.TwHDR exhibits high homology with HDRs of other plants,with an N-terminal conserved domain and three conserved cysteine residues.TwHDR cDNA was cloned into an expression vector and transformed into an Escherichia coli hdr mutant.Since loss-of-function E.coli hdr mutant is lethal,the result showed that transformation of TwHDR cDNA rescued the E.coli hdr mutant.This complementation assay suggests that the TwHDR cDNA encodes a functional HDR enzyme.The expression of TwHDR was induced by methyl-jasmonate(MJ) in T.wilfordii suspension cells.The expression of TwHDR reached the highest level after 1 h of MJ treatment.These results indicate that we have identified a functional TwHDR enzyme,which may play a pivotal role in the biosynthesis of diterpenoid triptolide in T.wilfordii. | Qiqing Cheng Yuru Tong Zihao Wang Ping Su Wei Gao Luqi Huang | 2017 | Acta Pharmaceutica Sinica B2017,7,2: | 5 |
| 3 | Ectopic expression of VRT-A2 underlies the origin of Triticum polonicum and Triticum petropavlovskyi with long outer glumes and grains显示文摘Polish wheat (Triticum polonicum) is a unique tetraploid wheat species characterized by an elongated outer glume. The genetic control of the long-glume trait by a single semi-dominant locus, P1 (from Polish wheat), was established more than 100 years ago, but the underlying causal gene and molecular nature remain elusive. Here, we report the isolation of VRT-A2, encoding an SVP-clade MADS-box transcription factor, as the P1 candidate gene. Genetic evidence suggests that in T. polonicum, a naturally occurring sequence rearrangement in the intron-1 region of VRT-A2 leads to ectopic expression of VRT-A2 in floral organs where the long-glume phenotype appears. Interestingly, we found that the intron-1 region is a key ON/OFF molecular switch for VRT-A2 expression, not only because it recruits transcriptional repressors, but also because it confers intron-mediated transcriptional enhancement. Genotypic analyses using wheat accessions indicated that the P1 locus is likely derived from a single natural mutation in tetraploid wheat, which was subsequently inherited by hexaploid T. petropavlovskyi. Taken together, our findings highlight the promoter-proximal intron variation as a molecular basis for phenotypic differentiation, and thus species formation in Triticum plants. | Jing Liu Zhaoyan Chen Zhihui Wang Zhaoheng Zhang Xiaoming Xie Zihao Wang Lingling Chai Long Song Xuejiao Cheng Man Feng Xiaobo Wang Yanhong Liu Zhaorong Hu Jiewen Xing Zhenqi Su Huiru Peng Mingming Xin Yingyin Yao Weilong Guo Qixin Sun Jie Liu Zhongfu Ni | 2021 | Molecular Plant2021,14,9: | 4 |
| 4 | Design of the real-time detection system based on LabVIEW for no-till seeder working performance显示文摘In order to ensure the working performance of the seeder,reduce the labor intensity of manual testing,and improve the efficiency and accuracy of the detection,a real-time detection system for detecting the performance of no-till seeders was designed based on the LabVIEW software platform of virtual instrument technology and the MCC USB-231 data acquisition card.The detection system can be used to detect the seeding quality index and residue cover index.The detection of the seeding quality index included the middle detection between the metering device and the opener,the end detection between the opener and the furrow.The result of the field test showed that the detection accuracies of seed quantity,multiple index,and miss index were 94.51%,92.83%,and 91.81%,respectively.The fault position can be accurately determined,and the measurement accuracy of residue cover index was 94.54%.The working performance of the no-tillage seeder can be monitored by the detection system to avoid the occurrence of reseeding and miss-seeding and improve production efficiency. | Huibin Zhu Cheng Qian Zihao Guo Lizhen Bai | 2021 | International Journal of Agricultural and Biological Engineering2021,14,5: | 3 |
| 5 | Frequency comb swept laser with a high-Q microring filter显示文摘Frequency comb swept lasers are the enabling technology of circular interferometric imaging.which was proposed to break the bottleneck of data acquisition and proessing in optical coherence tomography(OCT)at video rate.In this paper,we propose and demonstrate a highly coherent frequency comb swept laser by using a high-quality(high-Q)microring comb filter to discretize a Fourier domain mode-locked(FDML)laser.The microring filter has a Q factor of^2×10^6 and a linewidth of^90 MHz.To demonstrate the improvement in performance,a Fabry-Perot comb filter with a Q factor of 6.2×10^4 and a linewidth of 3.1 GHz is also used in the experiment for comparison.Both comb filters have free spectral ranges(FSRs)of^50 GHz for consistence.Stable and clearly discretized temporal waveforms and frequency comb spectra with 50 GHz FSR are observed.Adoption of the high-Q microring filter narrows the instantaneous linewidth of the FDML laser down to 1.5 GHz.The OCT system with the frequency comb swept laser source with a microring filter demonstrates an ultralong imaging range,which has a 6,10,and 15 dB sensitivity roll-off length of^53,~73,and over 100 mm,respectively. | DONGMEI HUANG FENG LI CHAO SHANG ZIHAO CHENG S.T.CHU P.K.A.WAI | 2020 | Photonics Research2020,8,6: | 2 |
| 6 | Catalytic hydrogenation performance of ZIF-8 carbide for electrochemical reduction of carbon dioxide显示文摘The conversion of CO_(2) electrocatalytic hydrogenation into energy-rich fuel is considered to be the most effective way to carbon recycle.Nitrogen-doping carbonized ZIF-8 is proposed as carrier of the earth-rich Sn catalyst to overcome the limit of electron transfer and CO_(2) adsorption capacity of Sn.Hierarchically porous structure of Sn doped carbonized ZIF-8 is controlled by hydrothermal and carbonization conditions,which induces much higher specific surface area than that of the commercial Sn nanoparticle(1003.174 vs.7.410 m^(2)·g^(-1)).The shift of nitrogen peaks in X-ray Photoelectron Spectroscopy spectra indicates interaction between ZIF-8 and Sn,which induces the shift of electron cloud from Sn to the chemical nitrogen to enhance conductivity and regulate electron transfer from catalyst to CO_(2).Lower mass transfer resistance and Warburg resistance are investigated through EIS,which significantly improves the catalytic activity for CO_(2) reduction reaction(CO_(2)RR).Onset potential of the reaction is reduced from-0.74 V to less than-0.54 V vs.RHE.The total Faraday efficiency of HCOOH and CO reaches 68.9%at-1.14 V vs.RHE,which is much higher than that of the commercial Sn(45.0%)and some other Sn-based catalyst reported in the literature. | Shuai Fan Huiyuan Cheng Manman Feng Xuemei Wu Zihao Fan Dongwei Pan Gaohong He | 2021 | Chinese Journal of Chemical Engineering2021,34,11: | 2 |
| 7 | 系统药理学方法发现汉黄芩苷作为新型三阴性乳腺癌血管生成抑制剂靶向Hedgehog通路显示文摘文章简介三阴性乳腺癌(TNBC)是一种侵袭性和异质性疾病,由于临床上缺乏可靶向的遗传突变,因而限制了靶向治疗的应用。近年来,系统生物学和多组学技术的崛起,极大地促进了系统药理学等网络方法在药物发现中的应用。 | 黄玉杰 方坚松 卢伟强 Zihao Wang Qi Wang Yuan Hou Xingwu Jiang Ofer Reizes Justin Lathia Ruth Nussinov Charis Eng Feixiong Cheng | 2020 | 科学新闻2020,,2: | 2 |
| 8 | Reconfigurable time-stretched swept laser source with up to 100 MHz sweep rate,100 nm bandwidth,and 100 mm OCT imaging range显示文摘The sweep rate,sweep range,and coherence length of swept sources,respectively,determine the acquisition rate,axial resolution,and imaging range of optical coherence tomography(OCT).In this paper,we demonstrate a reconfigurable high-speed and broadband swept laser by time stretching of a flat spectrum femtosecond pulse train with over 100 nm bandwidth and a repetition rate of 100 MHz.By incorporating an optical modulator and utilizing appropriate dispersive modules,the reconfiguration of the swept source is demonstrated with sweep rates of 25 and 2.5 MHz.The 2.5 MHz swept source enables an imaging range of>110 mm with 6 dB sensitivity rolloff in OCT,which is the longest imaging range ever reported for megahertz OCT. | DONGMEI HUANG FENG LI CHAO SHANG ZIHAO CHENG P.K.A.WAI | 2020 | Photonics Research2020,8,8: | 1 |
| 9 | Programmed death ligand-1 regulates angiogenesis and metastasis by participating in the c-JUN/VEGFR2 signaling axis in ovarian cancer显示文摘Background:Although programmed cell death-ligand 1(PD-L1)plays a wellknown function in immune checkpoint response by interacting with programmed cell death-1(PD-1),the cell-intrinsic role of PD-L1 in tumors is still unclear.Here,we explored the molecular regulatory mechanism of PD-L1 in the progression and metastasis of ovarian cancer.Methods:Immunohistochemistry of benign tissues and ovarian cancer samples was performed,followed by migration,invasion,and angiogenesis assays in PDL1-knockdown ovarian cancer cells.Immunoprecipitation,mass spectrometry,and chromatin immunoprecipitation were conducted along with zebrafish and mouse experiments to explore the specific functions and mechanisms of PD-L1 in ovarian cancer.Results:Our results showed that PD-L1 induced angiogenesis,which further promoted cell migration and invasion in vitro and in vivo of ovarian cancer.Mechanistically,PD-L1 was identified to directly interact with vascular endothelial growth factor receptor-2(VEGFR2)and then activated the FAK/AKT pathway,which further induced angiogenesis and tumor progression,leading to poor prognosis of ovarian cancer patients.Meanwhile,PD-L1 was found to be regulated by the oncogenic transcription factor c-JUN at the transcriptional level,which enhanced the expression of PD-L1 in ovarian cancer.Furthermore,we demonstrated that PD-L1 inhibitor durvalumab,combined with the antiangiogenic drug,apatinib,could enhance the effect of anti-angiogenesis and the inhibition of cell migration and invasion.Conclusion:Our results demonstrated that PD-L1 promoted the angiogenesis and metastasis of ovarian cancer by participating in the c-JUN/VEGFR2 signaling axis,suggesting that the combination of PD-L1 inhibitor and antiangiogenic drugs may be considered as a potential therapeutic approach for ovarian cancer patients. | Yufei Yang Lingfang Xia Yong Wu Hongyu Zhou Xin Chen Haoran Li Midie Xu Zihao Qi Ziliang Wang Huizhen Sun Xi Cheng | 2021 | Cancer Communications2021,41,6: | 1 |
| 10 | Fast Remaining Capacity Estimation for Lithium-ion Batteries Based on Short-time Pulse Test and Gaussian Process Regression显示文摘It remains challenging to effectively estimate the remaining capacity of the secondary lithium-ion batteries that have been widely adopted for consumer electronics,energy storage,and electric vehicles.Herein,by integrating regular real-time current short pulse tests with data-driven Gaussian process regression algorithm,an efficient battery estimation has been successfully developed and validated for batteries with capacity ranging from 100%of the state of health(SOH)to below 50%,reaching an average accuracy as high as 95%.Interestingly,the proposed pulse test strategy for battery capacity measurement could reduce test time by more than 80%compared with regular long charge/discharge tests.The short-term features of the current pulse test were selected for an optimal training process.Data at different voltage stages and state of charge(SOC)are collected and explored to find the most suitable estimation model.In particular,we explore the validity of five different machine-learning methods for estimating capacity driven by pulse features,whereas Gaussian process regression with Matern kernel performs the best,providing guidance for future exploration.The new strategy of combining short pulse tests with machine-learning algorithms could further open window for efficiently forecasting lithium-ion battery remaining capacity. | Aihua Ran Ming Cheng Shuxiao Chen Zheng Liang Zihao Zhou Guangmin Zhou Feiyu Kang Xuan Zhang Baohua Li Guodan Wei | 2023 | Energy & Environmental Materials2023,6,3: | 1 |
| 11 | hsa-mir-181a and hsa-mir-181b function as tumor suppressors in human glioma cells显示文摘 | Lei Shi Zihao Cheng Junxia Zhang Rui Li Peng Zhao Zhen Fu Yongping You | 2008 | Brain Research2008,,: | 1 |
| 12 | Bone morphogenetic protein 4 (BMP4) promotes hepatic glycogen accumulation and reduces glucose level in hepatocytes through mTORC2 signaling pathway显示文摘Liver is an important organ for regulating glucose and lipid metabolism.Recent studies have shown that bone morphogenetic proteins(BMPs)may play important roles in regu-lating glucose and lipid metabolism.Inour previous studies,we demonstrated that BMP4 signif-icantly inhibits hepatic steatosis and lowers serum triglycerides,playing a protective role against the progression of non-alcoholic fatty liver disease(NAFLD).However,the direct impact of BMP4 on hepatic glucose metabolism is poorly understood.Here,we investigated the regulatory roles of BMP4 in hepatic glucose metabolism.Through a comprehensive analysis of the 14 types of BMPs,we found that BMP4 was one of the most potent BMPs in promoting hepatic glycogen accumulation,reducing the level of glucose in hepatocytes and effecting the expression of genes related to glucose metabolism.Mechanistically,we demonstrated that BMP4 reduced the hepatic glucose lewels through the activation of mTORC2 signaling pathway in vitro and in wivo.Collectively,our findings strongly suggest that BMP4 may play an essential role in regulating hepatic glucose metabolism.This knowledge should aid us to understand the molecular pathogenesis of NAFLD,and may lead to the development of novel therapeutics by exploiting the inhibitory effects of BMPs on hepatic glucose and lipid metabolism. | Liqin An Qiong Shi Ying Zhu Hao Wang Qi Peng Jinghong Wu Yu Cheng Wei Zhang Yanyu Yi Zihao Bao Hui Zhang Yetao Luo Jiaming Fan | 2021 | Genes & Diseases2021,8,4: | 1 |
| 13 | Power system transient stability assessment based on the multiple paralleled convolutional neural network and gated recurrent unit显示文摘In order to accurately evaluate power system stability in a timely manner after faults,and further improve the feature extraction ability of the model,this paper presents an improved transient stability assessment(TSA)method of CNN+GRU.This comprises a convolutional neural network(CNN)and gated recurrent unit(GRU).CNN has the feature extraction capability for a micro short-term time sequence,while GRU can extract characteristics contained in a macro long-term time sequence.The two are integrated to comprehensively extract the high-order features that are contained in a transient process.To overcome the difficulty of sample misclassification,a multiple parallel(MP)CNN+GRU,with multiple CNN+GRU connected in parallel,is created.Additionally,an improved focal loss(FL)func-tion which can implement self-adaptive adjustment according to the neural network training is introduced to guide model training.Finally,the proposed methods are verified on the IEEE 39 and 145-bus systems.The simulation results indicate that the proposed methods have better TSA performance than other existing methods. | Shan Cheng Zihao Yu Ye Liu Xianwang Zuo | 2022 | Protection and Control of Modern Power Systems2022,7,1: | 1 |
| 14 | Role of innate immunity in SARS-CoV-2 infection显示文摘During severe acute respiratory syndrome coronavirus 2(SARS‐CoV‐2)infection,activated macrophages,dendritic cells(D.C.),neutrophils,and natural killer(N.K.)cells are the first defense against infection.These immune effectors trap and ingest the virus,kill infected epithelial cells,or produce anti‐viral cytokines.Evidence suggests that aging,obesity,and mental illness can lead to weakened innate immunity and,thus,are all associated with elevated infection and severe disease progression of coronavirus disease 2019(COVID‐19).Innate immune defense networks play a fundamental role in suppressing viral replication,infection establishment,and viral pathogenesis of SARS‐CoV‐2 and other respiratory viruses. | Zihao Wang Fang Cheng Yuxiu Xu Xin Li Songdong Meng | 2023 | Biosafety and Health2023,5,5: | 0 |
| 15 | Interlayer exciton dynamics of transition metal dichalcogenide heterostructures under electric fields显示文摘Stacking single layers of atoms on top of each other provides a fundamental way to achieve novel material systems and engineer their physical properties,which offers opportunities for exploring fundamental physics and realizing next-generation optoelectronic devices.Among the two-dimensional(2D)-stacked systems,transition metal dichalcogenide(TMDC)heterostructures are particularly attractive because they host tightly-bonded interlayer excitons which possess various novel and appealing properties.These interlayer excitons have drawn significant research attention and hold high potential for the application in unique optoelectronic devices,such as polarization-and wavelength-tunable single photon emitters,valley Hall transistors,and possible high-temperature superconductors.The development of these devices requires a comprehensive understanding of the fundamental properties of these interlayer excitons and the impact of electric fields on their behaviors.In this review,we summarize the recent advances on the understanding of interlayer exciton dynamics under electric fields in TMDC heterostructures.We put emphasis on the electrical modulation of interlayer excitons’emission,the valley Hall transport of charge carriers after the separation of interlayer excitons by an electric field,and the correlation physics of interlayer excitons and charges under electrical doping and tuning.Challenges and perspectives are finally discussed for the application of TMDC heterostructures in future optoelectronics. | Jian Tang Yue Zheng Ke Jiang Qi You Zhentian Yin Zihao Xie Henan Li Cheng Han Xiaoxian Zhang Yumeng Shi | 2024 | Nano Research2024,17,5: | 0 |
| 16 | Mechanical properties and damage characteristics of solidified body-coal combination in continuous driving and gangue backfilling显示文摘Recovery of the coal buried under buildings,railways and water bodies and the residual coal in irregularly arranged fully mechanized mining faces is a common engineering problem facing underground coal mining.In this study,a mining technology of continuous driving and gangue backfilling(CDGB)was proposed.The technology,which can not only alleviate ground subsidence and gangue discharge,but also release the above-mentioned coals,contributes to green and efficient sustainable development of mining.The stability of the system of the solidified body-reserved coal pillar combination(S-C combination)is crucial to the CDGB technology.Therefore,it is of great significance to explore the mechanical and damage characteristics of S-C combination in the synergistic bearing process.First,four sets of differentshaped S-C combination specimens were fabricated and a S-C combination bearing structure in CDGB was constructed to explore the differences in mechanical characteristics and damage modes of different-shaped S-C combination specimens during CDGB.Subsequently,their surface strain field evolutions and acoustic emission(AE)response characteristics in the load-bearing process were obtained with the aid of the digital image correlation technique and the AE signal monitoring system.Furthermore,a damage evolution model based on AE parameters and mechanical parameters was established to clarify the damage evolution law.The following results were obtained:(1)The free area of S-C combination can serve as a quantitative index to evaluate the stability of the overburden control system;(2)The concept of critical value k of the free area was first proposed.When the free area exceeds the critical value k(free area ratio greater than 1.13),the deformation resistance and the free area changes becomes negatively correlated;(3)As the free area expands,the failure of the S-C combination specimen evolves from tensile failure to shear failure.The distribution characteristics of the axial strain field also verified such a change in the failure mode;(4)When the free area expands,the peak AE count gradually changes from“double peaks”to“a single peak”.In this process,the expansion of free area shortens the time for accumulating and releasing energy during loading.Micro cracks generated in the specimen change from a phased steep growth to a continuous increase,and the process in which micro cracks develop,converge,intersect and connect to form macro cracks accelerates.The damage evolution law concluded based on AE parameters and mechanical parameters can well characterize the damage evolution process of S-C combination,providing certain reference for the study on the synergistic bearing of S-C combination during CDGB. | Yi Tan Hao Cheng Wenbing Guo Erhu Bai Shaopu Zhang Yu Wang Zihao Li | 2023 | International Journal of Mining Science and Technology2023,33,10: | 0 |
| 17 | Determination of Double Beta Decay Half-Life of 136Xe with the PandaX-4T Natural Xenon Detector显示文摘Precise measurement of two-neutrino double beta decay(DBD)half-life is an important step for the searches of Majorana neutrinos with neutrinoless double beta decay.We report the measurement of DBD half-life of 136xe using the Pandax-4T dual-phase Time Projection Chamber(TPC)with 3.7-tonne natural xenon and the first 94.9-day physics data release. | Lin Si Zhaokan Cheng Abdusalam Abdukerim Zihao Bo Wei Chen Xun Chen Yunhua Chen Chen Cheng Yunshan Cheng Xiangyi Cui Yingjie Fan Deqing Fang Changbo Fu Mengting Fu Lisheng Geng Karl Giboni Linhui Gu Xuyuan Guo Ke Han Changda He Jinrong He Di Huang Yanlin Huang Zhou Huang Ruquan Hou Xiangdong Ji Yonglin Ju Chenxiang Li Jiafu Li Mingchuan Li Shu Li Shuaijie Li Qing Lin Jianglai Liu Xiaoying Lu Lingyin Luo Yunyang Luo Wenbo Ma Yugang Ma Yujun Mao Yue Meng Nasir Shaheed Xiaofeng Shang Xuyang Ning Ningchun Qi Zhicheng Qian Xiangxiang Ren Changsong Shang Guofang Shen Wenliang Sun Andi Tan Yi Tao Anqing Wang Meng Wang Qiuhong Wang Shaobo Wang Siguang Wang Wei Wang Xiuli Wang Zhou Wang Yuehuan Wei Mengmeng Wu Weihao Wu Jingkai Xia Mengjiao Xiao Xiang Xiao Pengwei Xie Binbin Yan Xiyu Yan Yong Yang Chunxu Yu Jumin Yuan Ying Yuan Zhe Yuan Dan Zhang Minzhen Zhang Peng Zhang Shibo Zhang Shu Zhang Tao Zhang Li Zhao Qibin Zheng Jifang Zhou Ning Zhou Xiaopeng Zhou Yong Zhou | 2023 | Research2023,,2: | 0 |
| 18 | Missing Value Imputation for Radar-Derived Time-Series Tracks of Aerial Targets Based on Improved Self-Attention-Based Network显示文摘The frequent missing values in radar-derived time-series tracks of aerial targets(RTT-AT)lead to significant challenges in subsequent data-driven tasks.However,the majority of imputation research focuses on random missing(RM)that differs significantly from common missing patterns of RTT-AT.The method for solving the RM may experience performance degradation or failure when applied to RTT-AT imputation.Conventional autoregressive deep learning methods are prone to error accumulation and long-term dependency loss.In this paper,a non-autoregressive imputation model that addresses the issue of missing value imputation for two common missing patterns in RTT-AT is proposed.Our model consists of two probabilistic sparse diagonal masking self-attention(PSDMSA)units and a weight fusion unit.It learns missing values by combining the representations outputted by the two units,aiming to minimize the difference between the missing values and their actual values.The PSDMSA units effectively capture temporal dependencies and attribute correlations between time steps,improving imputation quality.The weight fusion unit automatically updates the weights of the output representations from the two units to obtain a more accurate final representation.The experimental results indicate that,despite varying missing rates in the two missing patterns,our model consistently outperforms other methods in imputation performance and exhibits a low frequency of deviations in estimates for specific missing entries.Compared to the state-of-the-art autoregressive deep learning imputation model Bidirectional Recurrent Imputation for Time Series(BRITS),our proposed model reduces mean absolute error(MAE)by 31%~50%.Additionally,the model attains a training speed that is 4 to 8 times faster when compared to both BRITS and a standard Transformer model when trained on the same dataset.Finally,the findings from the ablation experiments demonstrate that the PSDMSA,the weight fusion unit,cascade network design,and imputation loss enhance imputation performance and confirm the efficacy of our design. | Zihao Song Yan Zhou Wei Cheng Futai Liang Chenhao Zhang | 2024 | Computers, Materials & Continua2024,78,3: | 0 |
| 19 | Nanoengineered polypeptides from tetraphenylethylene-functionalized N-carboxyanhydride: Synthesis, self-assembly and intrinsic aggregation-induced emission显示文摘Ring-opening polymerization of N-carboxyanhydrides(NCAs)bearing pendant groups creates functional polypeptides.In this paper,we report the design,synthesis and polymerization of tetraphenylethylene(TPE)-modified NCA,which is used to incorporate aggregation-induced emission(AIE)-active segments into polypeptides.Specifically,we attempted the synthesis of amphiphilic methoxy poly(ethyleneglycol)-block-poly(γ-benzyl-L-glutamate)-block-poly(γ-4-(1,2,2-triphenylvinyl)benzyl-L-glutamate)(PEG-PBLG-PTPELG),which had well-controlled molecular weight and narrow polydispersity.The hydrophilic PEG and hydrophobic PBLG-PTPELG assembled into micelles in aqueous solution with diameter around 70 nm,displaying AIE at 480 nm.Our work demonstrates that the TPE-modified NCA is applicable for the preparation of the AIE-active polypeptides,integrating the AIE luminogens into the polypeptides which may offer unique opportunities for tuning AIE properties by adjusting the composition and conformation of polypeptides.We preliminarily explored the use of the amphiphilic polypeptides for the formulation of doxorubicin-containing micelles that can potentially be used for real-time monitoring of the nanomedicine distribution. | Xu Wang Zihao Zhao Tianrui Xue Zhengzhong Tan Ziyuan Song Shiqi Wei Yang Bo Ying Wang Jianjun Cheng | 2021 | Progress in Natural Science:Materials International2021,31,4: | 0 |
| 20 | Modulating of MoSe_(2)functional plane via doping-defect engineering strategy for the development of conductive and electrocatalytic mediators in Li-S batteries显示文摘The lithium polysulfide shuttle and sluggish sulfur reaction kinetics still pose significant challenges to lithium-sulfur(Li-S)batteries.The functional plane of Fe-MoSe_(2)@r GO nanohybrid with abundant defects has been designed and applied in Li-S batteries to develop the functional separator and multi-layer sulfur cathode.The cell with a functional separator exhibits a retention capacity of 462 m Ah g^(-1)after the 1000th at 0.5 C and 516 m Ah g^(-1)after the 600th at 0.3 C.Even at low electrolyte conditions(7.0μL_(mgsulfur)^(-1)and 15μL_(mgsulfur)^(-1))under high sulfur loadings(3.46 mg cm^(-2)and 3.73 mg cm^(-2)),the cell still presents high reversible discharge capacities 679 and 762 m Ah g^(-1)after 70 cycles,respectively.Further,at sulfur loadings up to 8.26 and 5.2 mg cm^(-2),the cells assembled with the bi-layers sulfur cathode and the tri-layers sulfur cathode give reversible capacities of 3.3 m Ah cm^(-2)after the 100th cycle and 3.0 m Ah cm^(-2)after the 120th cycle,respectively.This research not only demonstrates that the FeMoSe_(2)@r GO functional plane is successfully designed and applied in Li-S batteries with superior electrochemical performances but also paves the novel way for developing a unique multi-layer cathode technique to enhance and advance the electrochemical behavior of Li-S cells at a high-sulfur-loading cathode under lean electrolyte/sulfur(E/S)ratio. | Mohammed A.Al-Tahan Yutao Dong Aml E.Shrshr Xiyang Kang Hui Guan Yumiao Han Zihao Cheng Weihua Chen Jianmin Zhang | 2022 | Journal of Energy Chemistry2022,,12: | 0 |