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| 1 | Imaging pitfalls of pancreatic serous cystic neoplasm and its potential mimickers显示文摘The aim of this article is to clarify diagnostic pitfalls of pancreatic serous cystic neoplasm(SCN) that may result in erroneous characterization. Usual and unusual imaging findings of SCN as well as potential SCN mimickers are presented. The diagnostic key of SCN is to look for a cluster of microcysts(honeycomb pattern), which may not be always found in the center. Fibrosis in SCN may be mistaken for a mural nodule of intraductal papillary mucinous neoplasm(IPMN). The absence of cyst wall enhancement may be helpful to distinguish SCN from mucinous cystic neoplasm. However, oligocystic SCN and branch duct type IPMN may morphologically overlap. In addition, solid serous adenoma, an extremely rare variant of SCN, is difficult to distinguish from neuroendocrine tumor. | Kousei Ishigami Akihiro Nishie Yoshiki Asayama Yasuhiro Ushijima Yukihisa Takayama Nobuhiro Fujita Shunichi Takahata Takao Ohtsuka Tetsuhide Ito Hisato Igarashi Shuji Ikari Catherine M Metz Hiroshi Honda | 2014 | World Journal of Radiology2014，6，3： | 6 |
| 2 | 帮助, P53,和 Mlh1 蛋白质在的表示内视镜地 resected 区分类型的早胃的癌症显示文摘 AIM: To analyze the expression of the tumor-related proteins in differentiated-type early gastric carcinoma (DEGC) samples. METHODS: Tumor specimens were obtained from 102 patients (75 males and 27 females) who had received an endoscopic tumor resection at Tottori University Hospital between 2007 and 2009. Ninety-one cancer samples corresponded to noninvasive or intramucosal carcinoma according to the Vienna classification system, and 11 samples were submucosal invasive carcinomas. All of the EGCs were histologically differenti- ated carcinomas. All patients were classified as having Helicobacter pylori (H. pylori ) infections by endoscopic atrophic changes or by testing seropositive for H. pylori IgG. All of the samples were histopathologically classified as either tubular or papillary adenocarcinoma according to their structure. The immunohistochemi- cal staining was performed in a blinded manner with respect to the clinical information. Two independent observers evaluated protein expression. All data were statistically analyzed then. RESULTS: The rates of aberrant activation-induced cytidine deaminase (AID) expression and P53 overexpression were both 34.3% in DEGCs. The expression of Mlh1 was lost in 18.6% of DEGCs. Aberrant AID expression was not significantly associated with P53 overexpression in DEGCs. However, AID expression was associated with the severity of mononuclear cell activity in the non-cancerous mucosa adjacent to the tumor (P = 0.064). The rate of P53 expression was significantly greater in flat or depressed tumors than in elevated tumors. The frequency of Mlh1 loss was significantly increased in distal tumors, elevated gross-type tumors, papillary histological-type tumors, and tumors with a severe degree of endoscopic atrophic gastritis (P < 0.05). CONCLUSION: Aberrant AID expression, P53 overexpression, and the loss of Mlh1 were all associated with clinicopathological features and gastric mucosal alterations in DEGCs. The aberrant expression of AID protein may partly contribute to the induction of nuclear P53 expression. | Yohei Takeda Kazuo Yashima Akihiro Hayashi Shuji Sasaki Koichiro Kawaguchi Kenichi Harada Yoshikazu Murawaki Hisao Ito | 2012 | World Journal of Gastrointestinal Oncology2012，4，6： | 2 |
| 3 | SAP155-Mediated Splicing of FUSE-Binding Protein-Interacting Repressor Serves as a Molecular Switch for c-myc Gene Expression显示文摘 | Kazuyuki Matsushita Toshiko Kajiwara Mai Tamura Mamoru Satoh Nobuko Tanaka Takeshi Tomonaga Hisahiro Matsubara Hideaki Shimada Rei Yoshimoto Akihiro Ito Shuji Kubo Tohru Natsume David Levens Minoru Yoshida Fumio Nomura | 2012 | Molecular Cancer Research2012，，6： | 2 |
| 4 | Preoperative Ultrasonographic Examination for Lymph Node Metastasis: Usefulness when Designing Lymph Node Dissection for Papillary Microcarcinoma of the Thyroid显示文摘 | Yasuhiro Ito M.D. Ph.D. Chisato Tomoda M.D. Takashi Uruno M.D. Yuuki Takamura M.D. Akihiro Miya M.D. Kaoru Kobayashi M.D. Fumio Matsuzuka M.D. Kanji Kuma M.D. Akira Miyauchi M.D | 2004 | World Journal of Surgery2004，，5： | 1 |
| 5 | Reversible Right Ventricular Regional Non-Uniformity Quantified by Speckle-Tracking Strain Imaging in Patients With Acute Pulmonary Thromboembolism显示文摘 | Emiyo Sugiura Kaoru Dohi Katsuya Onishi Takeshi Takamura Akihiro Tsuji Satoshi Ota Norikazu Yamada Mashio Nakamura Tsutomu Nobori Masaaki Ito | 2009 | Journal of the American Society of Echocardiography2009，，12： | 1 |
| 6 | Correlation between Detection Rates of Periodontopathic Bacterial DNA in Carotid Coronary Stenotic Artery Plaque and in Dental Plaque Sample显示文摘 | Kazuyuki Ishihara Akihiro Nabuchi Rieko Ito | 2004 | Journal of Clinical Microbiology2004，42，3： | 1 |
| 7 | Platelet-derived RANK ligand enhances CCL17 secretion from dendritic cells mediated by thymic stromal lymphopoietin显示文摘 | Takahisa Nakanishi Muneo Inaba Noriko Inagaki-Katashiba Akihiro Tanaka Phan Thi Xuan Vien Kayoko Kibata Tomoki Ito Shosaku Nomura | 2014 | Platelets2014，，： | 1 |
| 8 | Excellent Prognosis of Patients with Solitary T1N0M0 Papillary Thyroid Carcinoma Who Underwent Thyroidectomy and Elective Lymph Node Dissection Without Radioiodine Therapy显示文摘 | Yasuhiro Ito Hiroo Masuoka Mitsuhiro Fukushima Hiroyuki Inoue Minoru Kihara Chisato Tomoda Takuya Higashiyama Yuuki Takamura Kaoru Kobayashi Akihiro Miya Akira Miyauchi | 2010 | World Journal of Surgery2010，，6： | 1 |
| 9 | Tetraarylethylene having two nitroxide groups:redox-switching of through-bond magnetic interaction by conformation change显示文摘 | Ito Akihiro Nakano Yoshiaki Kato Tatsuhisa | 2005 | Chemical Communications2005，，3： | 1 |
| 10 | Influence of learning curve on short-term results after laparoscopic resection for rectal cancer显示文摘 | Masaaki Ito Masanori Sugito Akihiro Kobayashi Yusuke Nishizawa Yoshiyuki Tsunoda Norio Saito | 2009 | Surgical Endoscopy2009，，2： | 1 |
| 11 | Suppression by estrogen receptor β of AP-1 mediated transactivation through estrogen receptor α显示文摘 | Satoshi Maruyama Nariaki Fujimoto Kohsuke Asano Akihiro Ito | 2001 | Journal of Steroid Biochemistry and Molecular Biology2001，，2： | 1 |
| 12 | Antiproliferative effects of isoflavones on human cancer cell lines established from the gastrointestinal tract显示文摘 | Kazuyoshi Yanagihara Akihiro Ito Tetsuya Toge | 1993 | Cancer Research1993，53，： | 1 |
| 13 | Risk factors for pancreatic stone formation in autoimmune pancreatitis over a long-term course显示文摘 | Masahiro Maruyama Norikazu Arakura Yayoi Ozaki Takayuki Watanabe Tetsuya Ito Suguru Yoneda Masafumi Maruyama Takashi Muraki Hideaki Hamano Akihiro Matsumoto Shigeyuki Kawa | 2012 | Journal of Gastroenterology2012，，5： | 1 |
| 14 | Long-term Outcomes after Intersphincteric Resection for Low-Lying Rectal Cancer显示文摘 | Norio Saito Masaaki Ito Akihiro Kobayashi Yusuke Nishizawa Motohiro Kojima Yuji Nishizawa Masanori Sugito | 2014 | Annals of Surgical Oncology2014，，11： | 1 |
| 15 | Transoral surgery for laryngo-pharyngeal cancer – The paradigm shift of the head and cancer treatment显示文摘 | Ichiro Tateya Akihiro Shiotani Yasuo Satou Masayuki Tomifuji Shuko Morita Manabu Muto Juichi Ito | 2015 | Auris Nasus Larynx2015，，： | 1 |
| 16 | Evaluation of cytologically benign solitary thyroid nodules by ultrasonography: A retrospective analysis of 1877 cases显示文摘 | Minoru Kihara Mitsuyoshi Hirokawa Hiroo Masuoka Tomonori Yabuta Hisakazu Shindo Takuya Higashiyama Mitsuhiro Fukushima Osamu Yamada Yuuki Takamura Yasuhiro Ito Kaoru Kobayashi Akihiro Miya Akira Miyauchi | 2012 | Auris Nasus Larynx2012，，： | 1 |
| 17 | An- tiproliferative effects of isoflavones on human cancer eelllines established from the gastrointestinal tract 显示文摘 | KAZUYOSHI YANAGIHARA AKIHIRO ITO TETSUYA TOGE | 1993 | Cancer Researoh1993，53，： | 1 |
| 18 | Sensitivity and Specificity of Intraoperative Recurrent Laryngeal Nerve Stimulation Test for Predicting Vocal Cord Palsy after Thyroid Surgery显示文摘 | Chisato Tomoda MD Yoshihiro Hirokawa MD Takashi Uruno MD Yuuki Takamura MD Yasuhiro Ito MD Akihiro Miya MD Kaoru Kobayashi MD Fumio Matsuzuka MD Kanji Kuma MD Akira Miyauchi MD | 2006 | World Journal of Surgery2006，，7： | 1 |
| 19 | Antiproliferative effects of isoflavones on human cancer cell lines established from the gastrointestinal tract显示文摘 | Kazuyoshi Yanagihara Akihiro Ito Tetsuya Toge | 1993 | Cancer Research1993，53，： | 1 |
| 20 | In vivo anti-inflammatory and antioxidant properties of ellagitannin metabolite urolithin A显示文摘 | Hidekazu Ishimoto Mari Shibata Yuki Myojin Hideyuki Ito Yukio Sugimoto Akihiro Tai Tsutomu Hatano | 2011 | Bioorganic & Medicinal Chemistry Letters2011，，19： | 1 |
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