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| 1 | 美国老年人家庭护理中不良事件防范探讨显示文摘从不同视角探讨了美国老年人在家庭护理过程中出现不良事件的防范措施和策略,以期为提高我国老年人家庭护理服务质量、降低家庭护理中不良事件的发生率提供参考和借鉴。 | 汤先萍 Bei Wu Chenjuan Ma | 2020 | 护理研究2020，34，21： | 4 |
| 2 | Continuous and comprehensive atmospheric observations in Beijing:a station to understand the complex urban atmospheric environment显示文摘Due to profound impact on climate and human health,air quality has attracted attention from all levels of the civil society.The key step in the provision of required tools for the society to tackle the complex air quality problem is to characterize it in a comprehensive manner with a long-term perspective.Here,we describe a continuous and comprehensive observation station and its accompanying state-ofthe-art instrumentation that was established to investigate the complex urban atmospheric environment in a rapidly developing Chinese Megacity.The station,located in downtown Beijing,aims to study air quality by identifying the major atmospheric pollutants and key processes determining their formation and loss mechanisms.A few hundreds of parameters are continuously measured with the state-of-the-art instruments,including trace gas concentrations,aerosol particle size distributions,and mass concentrations,covering aerosol particle chemical composition from molecules to micrometer-sized aerosol particles.This produced long-term,comprehensive big data with around 1�10^(11)bytes per year.In this paper,we provide an overview on the facilities of the station,the instrumentation used,the workflow of continuous observations and examples of results from 2018 to 2019 and a basis for establishing a modern long-term,comprehensive atmospheric urban observation station in other megacities. | Yongchun Liu Chao Yan Zemin Feng Feixue Zheng Xiaolong Fan Yusheng Zhang Chang Li Ying Zhou Zhuohui Lin Yishou Guo Ying Zhang Li Ma Wenshuo Zhou Zhikun Liu Lubna Dada Kaspar Dallenbach Jenni Kontkanen Runlong Cai Tommy Chan Biwu Chu Wei Du Lei Yao Yonghong Wang Jing Cai Juha Kangasluoma Tom Kokkonen Joni Kujansuu Anton Rusanen Chenjuan Deng Yueyun Fu Rujing Yin Xiaoxiao Li Yiqun Lu Yiliang Liu Chaofan Lian Dongsen Yang Weigang Wang Maofa Ge Yuesi Wang Douglas R.Worsnop Heikki Junninen Hong He Veli-Matti Kerminen Jun Zheng Lin Wang Jingkun Jiang Tuukka Petaja Federico Bianchi Markku Kulmala | 2020 | Big Earth Data2020，4，3： | 3 |
| 3 | Synthesis of two lanthanide clusters Ln^(Ⅲ)_(4)(Gd_(4) and Dy_(4)) with [2×2] square grid shape:Magnetocaloric effect and slow magnetic relaxation behaviors显示文摘Two isostructural tetranuclear lanthanide clusters named [Ln_(4)(L)_(4)(CH_(3) O)_(4)]·CH_(3) OH(Ln=Gd(Ⅲ) for 1,Dy(Ⅲ) for 2,H_(2) L=N’-(2-hydroxy-3-methoxybenzylidene)-6-(hydroxymethyl) picolinohydrazide) were successfully isolated by using a polydentate Schiff based ligand and Ln(Ⅲ) nitrate salts.The structures of 1 and 2 were characterized by X-ray structural analyses,they are held by four double deprotonated ligands L2-.In them all the lanthanide ions are eight-coordinated and distributed over four vertices of a parallelogram,presenting a Ln4 cluster with a strict [2 × 2] square grid pattern.The details of magnetic analysis show that 1 displays weak anti-ferromagnetic exchange between neighboring Gd(Ⅲ) ions through carboxylate oxygen and methanol oxygen ligand atoms.Furthermore,1 exhibits significant magnetocaloric effect with the maximum entropy change-ΔSm value of 28.5 J/(kg K) for ΔH=7.0 T at 2.0 K.For compound 2,remarkable slow magnetic relaxation behaviors are observed in the presence of zero magnetic field with τ0=1.02 × 10^(-6) s and energy barrier ΔE/kB=43.24 K. | Chunying Xu Zhilei Wu Chenjuan Fan Lili Yan Wenmin Wang Baoming Ji | 2021 | Journal of Rare Earths2021，39，9： | 2 |
| 4 | Three ne- w C19-diterpenoid alkaloids from Aconitum pendulum显示文摘 | Wang Yujie Zhang Jing Zeng Chenjuan | 2011 | Phytochem Lett2011，，4： | 1 |
| 5 | Using hierarchical agglomerative clustering in wireless sensor networks:An energy-efficient and flexible approach显示文摘 | Lung Chung-Horng Chenjuan Zhou | | 0，，3： | 1 |
| 6 | 显示文摘 | CHENJuan(陈娟) YETian-Nan(叶天南) ZHAOYong-Nan(赵永男) etal | | GaodengXuexiaoHuaxueXuebao0，，： | 1 |
| 7 | Effects of navigational works on morphological changes in the bar area of the Yangtze Estuary显示文摘 | Chenjuan Jiang Jiufa Li Huib E. de Swart | 2011 | Geomorphology2011，，： | 1 |
| 8 | Using hierarchical agglomerative clus- tering in wireless sensor networks:An energy-efficient and flexi- ble approach 显示文摘 | Lung C H Zhou Chenjuan | 2010 | Ad Hoc Networks2010，8，3： | 1 |
| 9 | Planet-satellite cage hybrids:covalent organic cages encircling metal organic cage显示文摘As a rising type of precisely molecular nanoobjects,porous molecular cages,including covalent organic cages(COCs) and metal organic cages(MOCs),have attracted much more attention.It is fascinating to construct well-defined cage hybrids combining COCs and MOCs to further rich their types,properties,and applications.However,it is a big challenge due to the isotropy of the porous molecular cages.In this article,an anisotropic COC ligand based on aryl ether bonds and bearing one isophthalate moiety has been designed and synthesized.Then planet-satellite cage hybrids(PSCHs),MOC@COCs,have been constructed through the coordination of the anisotropic COC ligand and copper ions with or without the help of extra dicarboxylic ligands in an almost quantitative manner for the first time.Three PSCHs with one different topological MOC(heteroleptic bipolar,distorted cuboctahedral or homoleptic cuboctahedral) as the planet and different numbers of COCs(6,12 or 24) as satellites are obtained.The structural and thermal properties of these PSCHs have also been studied.The obtained PSCHs exhibit discrete,uniform and stable structures,good solubility and strong film-forming property. | Chenjuan Yu Pan Yang Xinyuan Zhu Youfu Wang | 2022 | Science China Chemistry2022，65，5： | 0 |
| 10 | The Effect of cdk-5 Overexpression and Overactivation on Tau Hyperphosphorylation in Cultured N2a Cells显示文摘Neurofibrillary tangles (NFTs) are one of the neuropathological hallmarks of Alzheimer’s disease (AD) and abnormally hyperphosphorylated tau is the major protein of NFTs. It was reported that cyclin\|dependent kinase5 (Cdk\|5) could phosphorylate tau at most AD\|related epitopes in vivo. In this study, we investigated the effect of cdk\|5 overexpression on tau hyperphosphorylation in neuroblastoma N2a cells. We demonstrated that overexpression of cdk\|5 which resulted in a 3.5\|fold Cdk\|5 activation in the transfected cells induced a dramatic increase in phosphorylation of tau at several phosphorylation sites. Overexpression of cdk\|5 led to a reduced staining with antibody Tau\|1 and an enhanced staining with antibody PHF\|1, suggesting hyperphosphorylation of tau at Ser199/202 and Ser396/404 sites. It implies that in vitro overexpression of cdk\|5 leads to Cdk\|5 overactivation and tau hyperphosphorylation may be the underline mechanism. | CHENJuan LIHong-lian FENGYou-mei WANGjian-zhi | 2005 | Wuhan University Journal of Natural Sciences2005，10，2： | 0 |
| 11 | Measurement of atmospheric nanoparticles:Bridging the gap between gas-phase molecules and larger particles显示文摘Atmospheric nanoparticles are crucial components contributing to fine particulate matter(PM_(2.5)),and therefore have significant effects on visibility,climate,and human health.Due to the unique role of atmospheric nanoparticles during the evolution process from gas-phase molecules to larger particles,a number of sophisticated experimental techniques have been developed and employed for online monitoring and characterization of the physical and chemical properties of atmospheric nanoparticles,helping us to better understand the formation and growth of new particles.In this paper,we firstly review these state-of-the-art techniques for investigating the formation and growth of atmospheric nanoparticles(e.g.,the gas-phase precursor species,molecular clusters,physicochemical properties,and chemical composition).Secondly,we present findings from recent field studies on the formation and growth of atmospheric nanoparticles,utilizing several advanced techniques.Further-more,perspectives are proposed for technique development and improvements in measuring atmospheric nanoparticles. | Chao Peng Chenjuan Deng Ting Lei Jun Zheng Jun Zhao Dongbin Wang Zhijun Wu Lin Wang Yan Chen Mingyuan Liu Jingkun Jiang Anpei Ye Maofa Ge Weigang Wang | 2023 | Journal of Environmental Sciences2023，，1： | 0 |
| 12 | Overinhibition of Mitogen-Activated Protein Kinase Inducing Tau Hyperphosphorylation显示文摘To reveal the relationship between mitogen-activated protein kinase (MAPK) and tau phosphorylation, we used different concentration of PD98059, an inhibitor of MEK (MAPK kinase), to treat mice neuroblastma (N2a) cell line for 6 h. It showed that the activity of MAPK decreased in a dose-dependent manner. But Western blot and immunofluorescence revealed that just when the cells were treated with 16 μmol/L PD98059, tau was hyperphosphorylated at Ser396/404 and Ser199/202 sites. We obtained the conclusion that overinhibited MAPK induced tau hyperphosphorylation at Ser396/404 and Ser199/202 sites. | LIHong-lian CHENJuan LIUShi-jie ZHANGJia-yu WANGQun WANGJian-Zhi | 2005 | Wuhan University Journal of Natural Sciences2005，10，3： | 0 |
| 13 | Research progress on neutralizing epitopes and antibodies for the Rabies virus显示文摘Rabies is a zoonotic infectious disease with a high fatality rate.It is caused by a virus in the genus Lyssavirus and is a global public health threat.The rabies virus invades and infects cells mainly via a glycoprotein,which may involve multiple receptors.Neutralizing antibodies against the rabies virus function by blocking the binding of the glycoprotein to a receptor or preventing the membrane fusion process.Vaccination combined with anti-rabies virus neutralizing antibodies is essential for postexposure prophylaxis for category III exposure to the rabies virus.In this review,we discussed the neutralizing epitopes of the rabies virus and the neutralization mechanism of monoclonal antibodies.The neutralizing antibodies that have been commercialized or are under development are also summarized.Our review would provide a basis for the further development of safe and effective broadspectrum neutralizing antibodies to replace the rabies virus immunoglobulin in rabies post-exposure prophylaxis. | Chenjuan Shi Peilu Sun Pan Yang Lele Liu Li Tian Wenkai Liu Min Wang Xuexing Zheng Wenwen Zheng | 2022 | Infectious Medicine2022，1，4： | 0 |
| 14 | Theoretical Simulation on a Nonlinear Photonics Process of Er(1%)Yb(8%):FOV Oxyfluoride Nanophase Vitroceramics显示文摘We numerically simulate a photonics phenomenon of what we call intensity inversion between red and green fluorescence in oxyfluoride nanophase vitroceramics Er(1%)Yb(8%):FOV through the integration of whole fluorescence’s theories.We found that it is essential to introduce a coefficient presenting the difference between the Stokes energy transfer and anti-Stokes energy transfer processes in nano-material when calculating the energy transfer rate.Under this consideration,and with the total crystallized volume ratio set to be 17.6%,the simulation results of the population probabilities values of all energy levels of Er^(3+) ion are coincident with the experimental result perfectly. | Ce Wang Xiaobo Chen Gregory J.Salamo Naruhito Sawanobori Chenjuan He Hongyu Zhou Hongmei Jing Yongzhi Zeng Song Li Xiaoling Xu | 2010 | Communications in Computational Physics2010，7，3： | 0 |
| 15 | A mechanical model for the role of the neck linker during kinesin stepping and gating显示文摘In this paper, considering the different elastic properties in the attached head and the free head, we propose a physical model, in which the free head undergoes a diffusive search in an entropic spring potential formed by undocking the neck linker, and there are asymmetric conformational changes in the attached head formed by docking the neck linker to support the load force and bias the diffusive search to the forward direction. By performing the thermodynamic analysis, we obtain the free energy difference between forward and backward binding sites. And using the Fokker-Planck equation with two absorbing boundaries, we obtain the dependence of the ratio of forward to backward steps on the backward force. Also, within the Michaelis-Menten model, we investigate the dependence of the velocity-load relationship on the effective length of the junction between the two heads. The results show that our model can provide a physical understanding for the processive movement of kinesin. | WANG HaiYan HE ChenJuan | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，12： | 0 |
| 16 | S-doped graphene quantum dots as nanophotocatalyst for visible light degradation显示文摘Graphene quantum dots(GQDs) recently emerge as the new and appealing nanophotocatalyst because of their low-cost, environmental compatibility and the ability to facilitate the charge migration and prolong the charge lifetimes. In this work, a visible photocatalyst of S-doped graphene quantum dots(S-GQDs)was prepared by a facile hydrothermal synthesis using 1,3,6-trinitropyrene and Na_2 S as precursors. The well crystallization and monodispersity as well as the chemical environment of S-GQDs were characterized by transmission electron microscopy, atom force microscopy and X-ray photoelectron spectrum. A superior photocatalytic performance of S-GQDs was demonstrated for degradation of basic fuchsin under visible light irradiation. Furthermore, the possible photocatalytic mechanism was proposed based on the trapping experiments of active species. | Biting Huang Jingbo He Shiyue Bian Chenjuan Zhou Zhiyang Li Fengna Xi Jiyang Liu Xiaoping Dong | 2018 | Chinese Chemical Letters2018，29，11： | 0 |
| 17 | The missing base molecules in atmospheric acid–base nucleation显示文摘Transformation of low-volatility gaseous precursors to new particles affects aerosol number concentration,cloud formation and hence the climate.The clustering of acid and base molecules is a major mechanism driving fast nucleation and initial growth of new particles in the atmosphere.However,the acid–base cluster composition,measured using state-of-the-art mass spectrometers,cannot explain the measured high formation rate of new particles.Here we present strong evidence for the existence of base molecules such as amines in the smallest atmospheric sulfuric acid clusters prior to their detection by mass spectrometers.We demonstrate that forming(H_(2)SO_(4))1(amine)1 is the rate-limiting step in atmospheric H_(2)SO_(4)-amine nucleation and the uptake of(H_(2)SO_(4))1(amine)1 is a major pathway for the initial growth of H_(2)SO_(4)clusters.The proposed mechanism is very consistent with measured new particle formation in urban Beijing,in which dimethylamine is the key base for H_(2)SO_(4)nucleation while other bases such as ammonia may contribute to the growth of larger clusters.Our findings further underline the fact that strong amines,even at low concentrations and when undetected in the smallest clusters,can be crucial to particle formation in the planetary boundary layer. | Runlong Cai Rujing Yin Chao Yan Dongsen Yang Chenjuan Deng Lubna Dada Juha Kangasluoma Jenni Kontkanen Roope Halonen Yan Ma Xiuhui Zhang Pauli Paasonen Tuukka Petaja Veli-Matti Kerminen Yongchun Liu Federico Bianchi Jun Zheng Lin Wang Jiming Hao James N.Smith Neil M.Donahue Markku Kulmala Douglas R.Worsnop Jingkun Jiang | 2022 | National Science Review2022，9，10： | 0 |
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