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| 1 | The roles of macrophage autophagy in atherosclerosis显示文摘尽管药和治疗的各种各样的类型是可得到的对待动脉粥样硬化,它在全世界仍然是死亡的一个主要原因。巨噬细胞是泡沫房间的主要来源,它是动脉粥样硬化患者损害的特点。因而,在动脉粥样硬化的 pathophysiology 的巨噬细胞的角色逐渐地被调查。Autophagy 是一条自我保护的细胞的分解代谢的小径。自从它的发现, autophagy 被发现了与许多疾病被联系,包括心血管的疾病,恶意的肿瘤, neurodegenerative 疾病,和免疫系统混乱。积累的证据证明 autophagy 在禁止发炎和 apoptosis,并且在支持 efferocytosis 和胆固醇流出起一个重要作用。这些事实建议 autophagy 的正式就职可以为动脉粥样硬化的治疗作为潜在的策略被利用。在这评论,我们主要讨论在巨噬细胞之间的关系 autophagy 和动脉粥样硬化和分子的机制,以及在指向 autophagy 的过程到对待的最近的进展动脉粥样硬化。 | Bo-zong SHAO Bin-ze HAN Yan-xia ZENG Ding-feng SU Chong LIU | 2016 | Acta Pharmacologica Sinica2016，37，2： | 48 |
| 2 | Chemical constituents,biological functions and pharmacological effects for comprehensive utilization of Eucommia ulmoides Oliver显示文摘Eucommia ulmoides Oliver is a native plant and valuable tonic Chinese medicine in China with a long history,great economic value and comprehensive development potential.Traditionally,the comprehensive utilization rate of E.ulmoides Oliv.is still very low,only bark has been used as medicine and other parts of Eucommia ulmoides Oliv.cannot be fully utilized,even the leaves have been well utilized in food products in Japan in the past decades.In order to improve the comprehensive utilization efficiency of E.ulmoides Oliv.,in this review,we summarized the varieties and contents of main active compounds,biological functions and pharmacological effects in different parts of E.ulmoides Oliv.The findings suggest that other parts of E.ulmoides Oliv.could replace the bark of E.ulmoides Oliv.to some extent besides of their respective applications.The unique and extensive physiological functions between different parts of E.ulmoides Oliv.indicate that the comprehensive utilization of E.ulmoides Oliv.has a wide space to develop,which is also an effective way to protect E.ulmoides Oliv.resources and improve its the utilization rate. | Yi-Fan Xing Dong He Yi Wang Wen Zeng Chong Zhang Yuan Lu Nan Su Yan-Hua Kong Xin-Hui Xing | 2019 | Food Science and Human Wellness2019，8，2： | 18 |
| 3 | 3D graphene foam-supported cobalt phosphate and borate electrocatalysts for high-efficiency water oxidation显示文摘The cobalt phosphate-/cobalt borate-based oxygen-evolving catalysts(OECs) are the important class of earth-abundant electrocatalysts that can operate with high activity for water splitting under benign conditions.This article reports the integration of cobalt phosphate(CoPi) and cobalt borate(Co-Bi) OECs with three-dimensional(3D) graphene foam(GF) for the electrocatalytic water oxidation reaction. The GF showed a unique advantage to serve as a highly conductive 3D support with large capacity for anchoring and loading Co-OECs, thereby facilitating mass and charge transfer due to the large amount of active sites provided by the 3D graphene scaffold. As a result, this integrated system of GF and Co-OECs exhibits synergistically enhanced catalytic activity. The overpotential(g) of Co-Pi and Co-Bi/graphene catalysts is about 0.390 and0.315 V in neutral solutions, respectively. Besides, the integrated Co-OECs/graphene catalysts have also exhibited improved and stable oxygen evolution catalytic ability in alkaline solution. | Min Zeng Hao Wang Chong Zhao Jiake Wei Wenlong Wang Xuedong Bai | 2015 | Science Bulletin2015，60，16： | 10 |
| 4 | Development of Light Cycle Oil(LCO) Hydrocracking Technology over a Commercial W-Ni Based Catalyst显示文摘Because of its high density and low cetane number, the light cycle oil(LCO) containing heavy aromatics(60%—80%) can hardly be transformed through the conventional hydro-upgrading technology. In this report, a novel LCO hydrocracking technology(FD2G) was proposed for the utilization of LCO to manufacture high value-added products. Through the ingenious combination of hydroprocessing catalyst and the hydrocracking process, the high octane gasoline and the ultra-low sulfur diesel(ULSD) blendstocks were produced simultaneously. The influence of catalyst type, reaction temperature, pressure, respectively, on the research octane number(RON) of produced gasoline was studied in a fixed bed hydrogenation reactor. It indicated that high reaction temperature and medium pressure would favor the production of highoctane gasoline through the conversion of bi-aromatic and tri-aromatic hydrocarbons. The typical results of FD2 G technology on commercial units showed that it could produce clean diesel with a sulfur content of less than 10 μg/g and clean gasoline with a research octane number(RON) of up to 92. It would be contributed to the achievement of the maximum profit of a refinery, the FD2 G technology could provide a higher economic efficiency than the other diesel quality upgrading technology under the current gasoline and diesel price system. | Peng Chong Yang Xuejing Fang Xiangchen Huang Xinlu Cheng Zhenmin Zeng Ronghui Guo Rong | 2015 | China Petroleum Processing & Petrochemical Technology2015，17，4： | 9 |
| 5 | Fourth C hinese National Consensus Report on the management of H elicobacter pylori infection显示文摘 | Wen Zhong Liu Yong Xie Hong Cheng Nong Hua Lu Fu Lian Hu Wan Dai Zhang Li Ya Zhou Ye Chen Zhi Rong Zeng Chong Wen Wang Shu Dong Xiao Guo Zong Pan Pin Jin Hu | 2013 | Journal of Digestive Diseases2013，，5： | 9 |
| 6 | Outcomes in children with biliary atresia following liver transplantation显示文摘BACKGROUND: Congenital biliary atresia is a rare condition characterized by idiopathic dysgenesis of the bile ducts. If untreated, congenital biliary atresia leads to liver cirrhosis, liver failure and premature death. The present study aimed to evaluate the outcomes of orthotopic liver transplantation in children with biliary atresia. METHOD: We retrospectively analyzed 45 patients with biliary atresia who had undergone orthotopic liver transplantation from September 2006 to August 2012. RESULTS: The median age of the patients was 11.0 months (5-102). Of the 45 patients, 41 were younger than 3 years old. Their median weight was 9.0 kg (4.5-29.0), 34 of the 45 patients were less than 10 kg. Thirty-one patients had undergone Kasai portoenterostomy prior to orthotopic liver transplantation. We performed 30 living donor liver transplants and 15 split liver transplants. Six patients died during a follow-up. The median follow-up time of surviving patients was 11.4 months (1.4-73.7). The overall 1-, 2- and 3-year survival rates were 88.9%, 84.4% and 84.4%, respectively. CONCLUSION: With advances in surgical techniques and management, children with biliary atresia after liver transplantation can achieve satisfactory survival in China, although there remains a high risk of complications in the early postoperative period. | Li-Ying Sun Yun-Sheng Yang Zhi-Jun Zhu Wei Gao Lin Wei Xiao-Ye Sun Wei Qu Wei Rao Zhi-Gui Zeng Chong Dong Jin-Peng Tu Jian Wang Yi-He Liu Yuan Liu Li-Xin Yu Yu Wang Jing Li Zhong-Yang Shen | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，2： | 8 |
| 7 | A new tripodal rhodamine B derivative as a highly selective and sensitive fluorescence chemosensor for copper(Ⅱ)显示文摘A new tripodal rhodamine B derivative 2 was designed and synthesized by tripodal trialdehyde and rhodamine B hydrazide for the first time. This derivative could be used as a fluorescent chemosensor for the selective and sensitive determination of copper(II) in Tris-HCl buffer and ethanol aqueous mixed media. Under the optimum conditions described herein,fluorescence enhancement at 557/577 nm was linearly related to the concentration of copper(II) in the range of 0.10 to 10.00×10-5 mol·L-1,with a corre-lation coefficient of R2=0.9964 (n=15) and a detection limit of 1.129×10-7 mol·L-1 (the relative standard deviation for five repeated measurements at 4.00×10-5 mol·L-1 Cu(II) was 2.2%). The absorbance meas-urements at 557 nm were linearly related to the concentration of Cu(II) in the range of 0.50 to 25.00×10-5 mol·L-1,with a correlation coefficient of R2=0.9948 (n=13) and a detection limit of 3.338×10-7mol·L-1. | ZENG Xi,WU Chong,DONG Lei,MU Lan,XUE SaiFeng & TAO Zhu College of Chemistry and Chemical Engineering ,Guizhou University,Guiyang 550003,China Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province,Guizhou University,Guiyang 550025,China | 2009 | Science China Chemistry2009，52，4： | 7 |
| 8 | Development of a Rapid Multi-residue Assay for Detecting β-lactams Using Penicillin Binding Protein 2x显示文摘Objective To develop a rapid multi-residue assay for detecting 16 demanded by the European Union (EU). Methods A recombinant penicillin-binding protein(PBP)2x* from Streptococcus pneumoniae R6 was expressed in vitro and six β-lactams were conjugated to HRP by four methods.A rapid multi-residue assay for β-lactams was established with PBP2x* and HRP-conjugate. Results PBP2x* was expressed and purified successfully and the ideal HRP-conjugate was identified. The multi-residue assay was developed.After optimization,penicillin G,ampicillin,amoxicillin, cloxacillin,dicloxacillin,oxacillin,nafcillin,cephalexin,ceftiofur,cefaIonium,cefquinome,cefazolin, cefoperazone,cephacetrile,and cephapirin can be detected at levels below MRL in milk with simple pretreatment. Conclusion This assay developed can detect all 16 β-lactams demanded by the European Union(EU). The whole procedure takes only 45 min and can detect 42 samples and the standards with duplicate analysis. | ZENG Kum ZHANG Jing WANG Yang WANG ZhanHui ZHANG Su Xia WU Chong Ming SHEN Jian Zhong | 2013 | Biomedical and Environmental Sciences2013，26，2： | 7 |
| 9 | High efficiency all-dielectric pixelated metasurface for near-infrared full-Stokes polarization detection显示文摘Pixelated metasurfaces integrating both the functions of linear polarization and circular polarization filters on a single platform can achieve full-Stokes polarization detection.At present,the pixelated full-Stokes metasurfaces mainly face the following problems:low transmission,low circular dichroism(CD)of circular polarization filters,and high requirements in fabrication and integration.Herein,we propose high performance ultracompact all-dielectric pixelated full-Stokes metasurfaces in the near-infrared band based on silicon-on-insulator,which is compatible with the available semiconductor industry technologies.Circular polarization filters with high CD are achieved by using simple two-dimensional chiral structures,which can be easily integrated with the linear polarization filters on a single chip.In addition,the dielectric materials have higher transmission than metal materials with intrinsic absorption.We experimentally demonstrated the circular polarization filter with maximum CD up to 70%at a wavelength of 1.6μm and average transmission efficiency above 80%from 1.48μm to 1.6μm.Therefore,our design is highly desirable for many applications,such as target detection,clinical diagnosis,and polarimetric imaging and sensing. | Chong Zhang Jingpei Hu Yangeng Dong Aijun Zeng Huijie Huang Chinhua Wang | 2021 | Photonics Research2021，9，4： | 6 |
| 10 | Increased hepatic peroxisome proliferator-activated receptor coactivator-la expression precedes the development of insulin resistance in offspring of rats from severe hyperglycemic mothers显示文摘 | MA Jing-mei ZENG Chan-juan ZHANG Li SHOU Chong YANG Hui-xia | 2012 | Chinese Medical Journal2012，，7： | 6 |
| 11 | Combined effects of ultrasonic vibration and manganese on Fe-containing inter-metallic compounds and mechanical properties of Al-17Si alloy with 3wt.%Fe显示文摘The research studied the combined effects of ultrasonic vibration (USV) and manganese on the Fe-containing inter-metallic compounds and mechanical properties of Al-17Si-3Fe-2Cu-1Ni (wt.%) alloys. The results showed that, without USV, the alloys with 0.4wt.% Mn or 0.8wt.% Mn both contain a large amount of coarse plate-like δ-Al4(Fe,Mn)Si2 phase and long needle-like β-Al5(Fe,Mn)Si phase. When the Mn content changes from 0.4wt.% to 0.8wt.% in the alloys, the amount and the length of needle-like β-Al5(Fe,Mn)Si phase decrease and the plate-like δ-Al4(Fe,Mn)Si2 phase becomes much coarser. After USV treatment, the Fe-containing compounds in the alloys are refined and exist mainly as δ-Al4(Fe,Mn)Si2 particles with an average grain size of about 20 μm, and only a small amount of β-Al5(Fe,Mn)Si phase remains. With USV treatment, the ultimate tensile strengths (UTS) of the alloys containing 0.4wt.%Mn and 0.8wt.%Mn at room temperature are 253 MPa and 262 MPa, respectively, and the ultimate tensile strengths at 350 °C are 129 MPa and 135 MPa, respectively. It is considered that the modified morphology and uniform distribution of the Fe-containing inter-metallic compounds, which are caused by the USV process, are the main reasons for the increase in the tensile strength of these two alloys. | Lin Chong Wu Shusen Zeng Jinbiao An Ping Wan Li | 2013 | China Foundry2013，10，3： | 6 |
| 12 | Cancer-associated adipocyte-derived G-CSF promotes breast cancer malignancy via Stat3 signaling显示文摘Adipocyte is the most predominant cell type in the tumor microenvironment of breast cancer and plays a pivotal role in cancer progression,yet the underlying mechanisms and functional mediators remain elusive.We isolated primary preadipocytes from mammary fat pads of human breast cancer patients and generated mature adipocytes and cancer-associated adipocytes(CAAs)in vitro.The CAAs exhibited significantly different gene expression profiles as assessed by transcriptome sequencing.One of the highly expressed genes in CAAs is granulocyte colony-stimulating factor(G-CSF).Treatment with recombinant human G-CSF protein or stable expression of human G-CSF in triple-negative breast cancer(TNBC)cell lines enhanced epithelial–mesenchymal transition,migration,and invasion of cancer cells,by activating Stat3.Accordantly,targeting G-CSF/Stat3 signaling with G-CSF-neutralizing antibody,a chemical inhibitor,or siRNAs for Stat3 could all abrogate CAA-or G-CSF-induced migration and invasion of breast cancer cells.The pro-invasive genes MMP2 and MMP9 were identified as target genes of G-CSF in TNBC cells.Furthermore,in human breast cancer tissues,elevated G-CSF expression in adipocytes is well correlated with activated Stat3 signal in cancer cells.Together,our results suggest a novel strategy to intervene with invasive breast cancers by targeting CAA-derived G-CSF. | Li Liu Yudong Wu Cheng Zhang Chong Zhou Yining Li Yi Zeng Chunbo Zhang Rong Li Daya Luo Lieliang Wang Long Zhang Shuo Tu Huan Deng Shiwen Luo Ye-Guang Chen Xiangyang Xiong Xiaohua Yan | 2020 | Journal of Molecular Cell Biology2020，12，9： | 4 |
| 13 | The influence of ^(18)F-fluorodeoxyglucose positron emission tomography/computed tomography on the N-and M-staging and subsequent clinical management of intrahepatic cholangiocarcinoma显示文摘Background:Intrahepatic cholangiocarcinoma(ICC)is a highly metastatic cancer.^(18)F-fluorodeoxyglucose positron emission tomography/computed tomography(^(18)F-FDG PET/CT)enables sensitive tumor and metastasis detection.Our aim is to evaluate the influence of pre-treatment PET/CT on the N-and M-staging and subsequent clinical management in ICC patients.Methods:Between August 2010 and August 2018,660 consecutive ICC patients,without prior anti-tumor treatments nor other malignancies,were enrolled.The diagnostic performance of PET/CT on the N-and M-staging was compared with conventional imaging,and the preoperative staging accuracy and treatment re-allocation by PET/CT were retrospectively calculated.Survival difference was compared between patients receiving PET/CT or not after propensity score matching.Results:Patients were divided into group A(n=291)and group B(n=369)according to whether PET/CT was performed.Among 291 patients with both PET/CT and conventional imaging for staging in group A,PET/CT showed significantly higher sensitivity(83.0%vs.70.5%,P=0.001),specificity(88.3%vs.74.9%,P<0.001)and accuracy(86.3%vs.73.2%,P<0.001)than conventional imaging in diagnosing regional lymph node metastasis,as well as higher sensitivity(87.8%vs.67.6%,P<0.001)and accuracy(93.5%vs.89.3%,P=0.023)in diagnosing distant metastasis.Overall,PET/CT improved the accuracy of preoperative staging from 60.1%to 71.8%(P<0.001),and modified clinical treatment strategy in 5.8%(17/291)of ICC patients,with unique roles in different tumor-node-metastasis(TNM)stages.High tumor-to-non-tumor ratio(TNR)predicted poor overall survival[hazard ratio(HR)=2.17;95%confidence interval(CI):1.49-3.15;P<0.001].Furthermore,patients performing PET/CT had longer overall survival compared with those without PET/CT(HR=0.74;95%CI:0.58-0.93;P=0.011)after propensity score matching.Conclusions:PET/CT was valuable for diagnosing regional lymph node metastasis and distant metastasis in ICC patients,and facilitated accurate tumor staging and optimal treatment allocation. | Youpei Lin Huanhuan Chong Guohe Song Chenhao Zhang Liangqing Dong Ling Aye Fei Liang Shuaixi Yang Mengsu Zeng Guangyu Ding Shu Zhang Jieyi Shi Aiwu Ke Xiaoying Wang Jian Zhou Jia Fan Qiang Gao | 2022 | Hepatobiliary Surgery and Nutrition2022，11，5： | 3 |
| 14 | A redox-active conjugated microporous polymer cathode for highperformance lithium/potassium-organic batteries显示文摘Organic redox-active materials have emerged as a class of electrode materials for rechargeable batteries due to their high redox activity,low cost,structure diversity and flexibility.However,the high solubility of organic small molecules in organic electrolytes commonly leads to the fast capacity decay with cycling.Herein,we report a redox-active conjugated microporous polymer of poly(pyrene-co-anthraquinone)(Py Aq)cathode material consisting of pyrene and anthraquinone units.Benefiting from the highly cross-linked polymer structure with insoluble nature in organic electrolytes,the high surface area and the plentiful redox-active carbonyl groups,the Py Aq cathode demonstrates outstanding electrochemical performances for both lithium-ion batteries(LIBs)and potassium-ion batteries(KIBs).Specifically,the Py Aq cathode for LIBs delivers a high reversible capacity of 169 m Ah g^-1 at the current density of 20 m A g^-1,a high rate capability(142 m Ah g^-1 at 1000 m A g^-1)and an excellent cycling stability for 4000 cycles.Additionally,the Py Aq cathode for KIBs also exhibits a high reversible capacity of143 m Ah g^-1 with a long cycling life over 800 cycles.The excellent electrochemical performance demonstrates that the newly developed Py Aq could be an attractive cathode material for the advanced energy storage technologies. | Lian-Wei Luo Chong Zhang Peixun Xiong Yongbo Zhao Wenyan Ma Yu Chen Jing Hui Zeng Yunhua Xu Jia-Xing Jiang | 2021 | Science China Chemistry2021，64，1： | 3 |
| 15 | Histones released by NETosis enhance the infectivity of SARS-CoV-2 by bridging the spike protein subunit 2 and sialic acid on host cells显示文摘Neutrophil extracellular traps(NETs)can capture and kill viruses,such as influenza viruses,human immunodeficiency virus(HIV),and respiratory syncytial virus(RSV),thus contributing to host defense.Contrary to our expectation,we show here that the histones released by NETosis enhance the infectivity of SARS-CoV-2,as found by using live SARS-CoV-2 and two pseudovirus systems as well as a mouse model.The histone H3 or H4 selectively binds to subunit 2 of the spike(S)protein,as shown by a biochemical binding assay,surface plasmon resonance and binding energy calculation as well as the construction of a mutant S protein by replacing four acidic amino acids.Sialic acid on the host cell surface is the key molecule to which histones bridge subunit 2 of the S protein.Moreover,histones enhance cell-cell fusion.Finally,treatment with an inhibitor of NETosis,histone H3 or H4,or sialic acid notably affected the levels of sgRNA copies and the number of apoptotic cells in a mouse model.These findings suggest that SARS-CoV-2 could hijack histones from neutrophil NETosis to promote its host cell attachment and entry process and may be important in exploring pathogenesis and possible strategies to develop new effective therapies for COVID-19. | Weiqi Hong Jingyun Yang Jun Zou Zhenfei Bi Cai He Hong Lei Xuemei He Xue Li Aqu Alu Wenyan Ren Zeng Wang Xiaohua Jiang Kunhong Zhong Guowen Jia Yun Yang Wenhai Yu Qing Huang Mengli Yang Yanan Zhou Yuan Zhao Dexuan Kuang Junbin Wang Haixuan Wang Siyuan Chen Min Luo Ziqi Zhang Tiangi Lu Li Chen Haiying Que Zhiyao He Qiu Sun Wei Wang Guobo Shen Guangwen Lu Zhiwei Zhao Li Yang Jinliang Yang Zhenling Wang Jiong Li Xiangrong Song Lunzhi Dai Chong Chen Jia Geng Maling Gou Lu Chen Haohao Dong Yong Peng Canhua Huang Zhiyong Qian Wei Cheng Changfa Fan Yuquan Wei Zhaoming Su Aiping Tong Shuaiyao Lu Xiaozhong Peng Xiawei Wei | 2022 | Cellular & Molecular Immunology2022，19，5： | 2 |
| 16 | Suppressing laser phase noise in an optomechanical system显示文摘We propose a scheme to suppress the laser phase noise without increasing the optomechanical single-photon coupling strength.In the scheme,the parametric amplification terms,created by Kerr and Duffing nonlinearities,can restrain laser phase noise and strengthen the effective optomechanical coupling,respectively.Interestingly,decreasing laser phase noise leads to increasing thermal noise,which is inhibited by bringing in a broadband-squeezed vacuum environment.To reflect the superiority of the scheme,we simulate quantum memory and stationary optomechanical entanglement as examples,and the corresponding numerical results demonstrate that the laser phase noise is extremely suppressed.Our method can pave the way for studying other quantum phenomena. | Yexiong Zeng Biao Xiong Chong Li | 2022 | Frontiers of physics2022，17，1： | 2 |
| 17 | Internal connections between dietary intake and gut microbiota homeostasis in disease progression of ulcerative colitis:a review显示文摘Ulcerative colitis(UC)is a chronic systematic inflammation disorder with increasing incidence,unknown pathogenesis,limited drug treatment,and abundant medical expenses.Dietary intake,as a daily indispensable environment factor,is closely related to UC pathogenesis and prevention.The underlying interactions between dietary intake and UC progression are implicated with the modulation of gut microbiome as well as microbial metabolites,suggesting the complex and systematic characteristics of UC.However,the triangular relationships with dietary intake,gut microbiota homeostasis,and UC have not been well summarized so far.Here we review the recent studies of dietary intake on the regulation of gut microbiome homeostasis as well as modulation of UC progression.These findings suggest that varieties in dietary patterns result in the production of diverse microbial fermentation metabolites,which contribute to gut microbiome homeostasis through multiple manipulations including immune modulation,inftammation restriction as well as epithelial barrier maintenance,thus finally determine the fate of UC progression and give implications for functional food development for prevention and treatment of UC patients. | Wen Zeng Dong He Yifan Xing Junyu Liu Nan Su Chong Zhang Yi Wang Xinhui Xing | 2021 | Food Science and Human Wellness2021，10，2： | 2 |
| 18 | Topologies and control strategies of multi-functional grid-connected inverters for power quality enhancement: A comprehensive review显示文摘 | Zheng Zeng Huan Yang Rongxiang Zhao Chong Cheng | 2013 | Renewable and Sustainable Energy Reviews2013，，： | 2 |
| 19 | Conserved and differentiated functions of CIK receptor kinases in modulating stem cell signaling in Arabidopsis显示文摘The shoot apical meristem(SAM)and root apical meristem(RAM)act as pools of stem cells that give rise to aboveground and underground tissues and organs in higher plants,respectively.The CLAVATA3(CLV3)-WUSCHEL(WUS)negative-feedback loop acts as a core pathway controlling SAM homeostasis,while CLV3/EMBRYO SURROUNDING REGION(ESR)40(CLE40)and WUSCHEL-RELATED HOMEOBOX5(WOX5),homologs of CLV3 and WUS,direct columella stem cell fate.Moreover,CLV3 INSENSITIVE KINASES(CIKs)have been shown to be essential for maintaining SAM homeostasis,whereas whether they regulate the distal root meristem remains to be elucidated.Here,we report that CIKs are indispensable for transducing the CLE40 signal to maintain homeostasis of the distal root meristem.We found that the cik mutant roots displayed disrupted quiescent center and delayed columella stem cell(CSC)differentiation.Biochemical assays demonstrated that CIKs interact with ARABIDOPSIS CRINKLY4(ACR4)in a ligand-independent manner and can be phosphorylated by ACR4 in vitro.In addition,the phosphorylation of CIKs can be rapidly induced by CLE40,which partially depends on ACR4.Although CIKs act as conserved and redundant regulators in the SAM and RAM,our results demonstrated that they exhibit differentiated functions in these meristems. | Yafen Zhu Chong Hu Yanwei Cui Li Zeng Sunjingnan Li Mingsong Zhu Fanhui Meng Shuting Huang Li Long Jing Yi Jia Li Xiaoping Gou | 2021 | Molecular Plant2021，14，7： | 2 |
| 20 | Terahertz emission from localized modes in one-dimensional disordered systems [Invited]显示文摘We demonstrate terahertz(THz) frequency laser emission around 3.2 THz from localized modes in one-dimensional disordered grating systems. The disordered structures are patterned on top of the double-metal waveguide of a THz quantum cascade laser. Multiple emission peaks are observed within a frequency range corresponding to the bandgap of a periodic counterpart with no disorder, indicating the presence of mode localization aided by Bragg scattering. Simulations and experimental measurements provide strong evidence for the spatial localization of the THz laser modes. | YONGQUAN ZENG GUOZHEN LIANG Bo QIANG Bo MENG Hou KUN LIANG SHAMPY MANSHA JIANPING LI ZHAOHUI L LIANHE LI ALEXANDER GILES DAVIES EDMUND HAROLD LINFIELD YING ZHANG YIDONG CHONG AND Qi JIE WANG | 2018 | Photonics Research2018，6，2： | 1 |
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