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23篇 您的检索式:作者名="Changmin Li"
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1Red carbon dots as label-free two-photon fluorescent nanoprobes for imaging of formaldehyde in living cells and zebrafishes显示文摘Direct,in situ selective detection of intracellular formaldehyde(FA)is of great significance for understanding its function in FA-related diseases.Herein,red carbon dots(RCD)are reported as label-free two-photon fluorescent nanoprobes for detecting and imaging of FA.Upon addition of FA,the-NH2 groups of RCD could quickly and specially react with aldehydes to form Schiff base and then the strong fluorescence of RCD with blue-shift emission is recovery due to the destruction of the hydrogen bond interaction between RCD and water.In addition,the nanoprobes exhibit outsta nding photo stability,rapid response(<1 min),high sensitivity(~9.9μmol/L)and excellent selectivity toward FA over other aldehyde group compounds.Notably,owing to the good cell-membrane permeability and biocompatibility,as well as the large two-photon absorption cross-section,the as-prepared RCD can be used as label-free nanoprobes for selectively detecting and imaging FA in living cells and zebrafishes through one-photon and two-photon excitation.Moreover,RCD could stain the tissue of zebrafishes at depths interval of up to 240μm under two-photon excitation.This research implied that RCD are promising tools for directly and in situ imaging FA in vivo,thus providing critical insights into FA-related pathophysiological processes.Hong Wang Jing Wei Chonghua Zhang Yuan Zhang Yubin Zhang Lin Li Changmin Yu Peisheng Zhang Jian Chen 2020Chinese Chemical Letters2020,31,3:3
2OGT Mediated Histone H2B S112 Glc NAcylation Regulates DNA Damage Response显示文摘O-GlcNAcylation is an important post-translational modification and has been implicated in many fundamental cellular processes. Recent studies showed that O-linked N-acetylglucosamine(GlcNAc) transferase(OGT) mediated O-Glc NAcylation of histone H2B Ser 112(H2B S112 Glc NAcylation) plays an important role in gene transcription. However, the role of this histone modification in DNA damage response has not been studied yet. In this study, we found that OGT and OGT mediated H2B S112 Glc NAcylation are involved in DNA damage response for maintaining genomic stability and are required for resistance to many DNA-damaging and replication stressinducing agents. OGT mediated H2B S112 GlcNAcylation increased locally upon the induction of double-strand breaks(DSBs), and depletion of OGT or overexpression of H2B S112A mutant impaired homologous recombination(HR) and nonhomologous end-joining(NHEJ). Mechanistically, H2B S112 GlcNAcylation could bind Nijmegen breakage syndrome 1(NBS1) and regulate NBS1 foci formation. Taken together, our results demonstrate a new function of histone O-GlcNAcylation in DNA damage response(DDR).Panfei Wang Changmin Peng Xia Liu Hailong Liu Yali Chen Li Zheng Baolin Han Huadong Pei 2015Journal of Genetics and Genomics2015,42,9:3
3Recent progress in small molecule fluorescent probes for nitroreductase显示文摘Nitroreductase(NTR) is a member of flavin-containing enzymes that exists widely in bacteria. Hypoxia,which is a characteristic of locally advanced solid tumors, resulting from an imbalance between oxygen consumption and supply, can result in NTR overexpression. Using either nicotinamide adenine dinucleotide(NADH) or nicotinamide adenine dinucleotide phosphate(NADPH) as a source of reducing equivalents, NTR can catalyze the reduction of nitroaromatic compounds to the corresponding amines.Based on this reduction mechanism, NTR can be applied not only in the bioremediation and degradation of organic nitrogen compounds, but also in the development of NTR-targeted fluorescent probes to detect the hypoxic status of cancer cells. This review aims to provide a summary of the progress in fluorescent probes for NTR in recent years and elucidate the main fluorescent mechanisms that have been applied to design probes.Wenjing Qin Chenchen Xu Yanfei Zhao Changmin Yu Sheng Shen Lin Li Wei Huang 2018Chinese Chemical Letters2018,29,10:2
4Influences of Tibetan Plateau uplift on provenance evolution of the paleo-Pearl River显示文摘A comparative analysis of the geochemical characteristics of sediments from the Oligocene Zhuhai Formation(32-23.8 Ma),the Miocene Zhujiang Formation(23.8-16.5 Ma),and the Hanjiang Formation(16.5—10.5 Ma) and a comprehensive analysis of the geochemical characteristics of rocks surrounding the paleo-Pearl River drainage contribute to understanding the influences of the Tibetan Plateau uplift on provenance evolution of the paleo-Pearl River.The results show that the geochemical characteristics of sediments from the Oligocene Zhuhai Formation are very different from the geochemical characteristics of sediments from the Miocene Zhujiang and Hanjiang Formations.The ∑ rare earth elements(REE) of mudstone is relatively high in the Zhuhai Formation,204.07-293.88 ppm(average 240.46 ppm),and low in the Zhujiang and Hanjiang Formations,181.32-236.73 ppm(average 203.83 ppm) and 166.84-236.65 ppm(average199.04 ppm),respectively.The chemical index of alteration(CIA) for these samples has a similar trend to the∑ REE:the CIA of the Zhuhai Formation is relatively high and the CIA of the Zhujiang and Hanjiang Formations is relatively low.The uplift of the Tibetan Plateau is crucial to the westward expansion of the paleo-Pearl River drainage.Ye Yu Changmin Zhang Shaohua Li Rui Zhu Jiangyan Liu Chenggang Qin Zhongtao Zhang 2015Chinese Journal Of Geochemistry2015,34,2:2
5Application and improvement of stamping automation technology 显示文摘Li Zhenkui Liu Changmin 2012Forging & Metalforming2012,,16:1
6COST REDUCTION OF CEMENTING FILL IN KANGJIAWAN MINE显示文摘COSTREDUCTIONOFCEMENTINGFILLINKANGJIAWANMINEWangXinmin,ZhangQinliDepartmentofResourcesExploitationEnginering,CentralSouthUniv...Wang, Xinmin Zhang, Qinli Chen, Changmin Li, Yanping 1997中国有色金属学会会刊:英文版1997,7,1:1
7Preparation of TiO2 Nanoflakes and Their Influence on Lithium Ion Battery Storage Performance显示文摘LI Yi HAN Xiangbo LIANG Jicai LENG Xuning YE Kaiqi HOU Changmin YU Kaifeng 2015Chemical Research in Chinese Universities2015,31,3:1
8Tradable travel credits for congestion management with heterogeneous users显示文摘Wang Xiaolei Yang Hai Zhu Daoli Li Changmin 2012Transportation Research Part E2012,48,2:1
9Tradable travel credits for congestion management with heterogeneous users显示文摘Xiaolei Wang Hai Yang Daoli Zhu Changmin Li 2012Transportation Research Part E2012,48,2:1
10Wearable Sweat Biosensors Refresh Personalized Health/Medical Diagnostics显示文摘Sweat contains a broad range of critical biomarkers including ions,small molecules,and macromolecules that may indirectly or directly reflect the health status of the human body and thereby help track disease progression.Wearable sweat biosensors enable the collection and analysis of sweat in situ,achieving real-time,continuous,and noninvasive monitoring of human biochemical parameters at the molecular level.This review summarizes the physiological/pathological information of sweat and wearable sweat biosensors.First,the production of sweat pertaining to various electrolytes,metabolites,and proteins is described.Then,the compositions of the wearable sweat biosensors are summarized,and the design of each subsystem is introduced in detail.The latest applications of wearable sweat biosensors for outdoor,hospital,and family monitoring are highlighted.Finally,the review provides a summary and an outlook on the future developments and challenges of wearable sweat biosensors with the aim of advancing the field of wearable sweat monitoring technology.Wenhui Ji Jingyu Zhu Wanxia Wu Nanxiang Wang Jiqing Wang Jiansheng Wu Qiong Wu Xuewen Wang Changmin Yu Gaofeng Wei Lin Li Fengwei Huo 2021Research2021,,1:1
11Tradable travel credits for congestion management with heterogeneous users显示文摘Xiaolei Wang Hai Yang Daoli Zhu Changmin Li 2011Transportation Research Part E2011,,2:1
12Photoluminescence Characterization of Sm 3+ -Doped Fluoroborate Ceramics显示文摘Li Changmin Yang Dianlai Zhang Yingying Wang Zhiqiang Li Hai 2007Journal of Rare Earths2007,,:1
13Wearable Sweat Biosensors Refresh Personalized Health/Medical Diagnostics显示文摘Sweat contains a broad range of critical biomarkers including ions,small molecules,and macromolecules that may indirectly or directly reflect the health status of the human body and thereby help track disease progression.Wearable sweat biosensors enable the collection and analysis of sweat in situ,achieving real-time,continuous,and noninvasive monitoring of human biochemical parameters at the molecular level.This review summarizes the physiological/pathological information of sweat and wearable sweat biosensors.First,the production of sweat pertaining to various electrolytes,metabolites,and proteins is described.Then,the compositions of the wearable sweat biosensors are summarized,and the design of each subsystem is introduced in detail.The latest applications of wearable sweat biosensors for outdoor,hospital,and family monitoring are highlighted.Finally,the review provides a summary and an outlook on the future developments and challenges of wearable sweat biosensors with the aim of advancing the field of wearable sweat monitoring technology.Wenhui Ji Jingyu Zhu Wanxia Wu Nanxiang Wang Jiqing Wang Jiansheng Wu Qiong Wu Xuewen Wang Changmin Yu Gaofeng Wei Lin Li Fengwei Huo 2022Research2022,,1:1
14Mitochondria-targeted fluorescent probe based on vibration-induced emission for real-time monitoring mitophagy-specific viscosity dynamic显示文摘Directly monitoring mitophagy-specific viscosity dynamic in living cells is of great significance but remains challenging.Herein,this study reported a novel mitochondria-targeted fluorescent probe DPACDY based on vibration-induced emission(VIE)for monitoring viscosity changes during mitochondrial autophagy.This probe contained N,N’-diphenyl-dihydrodibenzo[a,c]phenazine(DPAC)as the VIE core and two positively charged pyridinium moieties for mitochondria anchoring.As the ambient viscosity increased,the vibration of DPAC-DY could be hindered,and subsequently resulting in the enhancement of fluorescence emission.In vitro and intracellular experiments indicated that the probe DPAC-DY showed highly sensitive response to viscosity due to VIE mechanism.Importantly,by virtue of this probe,in situ and real-time visualization of the specific viscosity dynamics during the mitochondrial autophagy process was achieved.Thus,this work provides a novel strategy for VIE-based viscosity response sensors applied to specific organelles and offers a platform for in-depth study of mitochondrial viscosity-related diseases.Shuangxi Wang Bicong Zhou Na Wang Changmin Yu Naidi Yang Jian Chen Qiong Wu Chengwu Zhang Lin Li Wei Huang 2020Chinese Chemical Letters2020,31,11:1
15Prepara- tion and property analysis of a heat - resistant and anti - eroding coating 显示文摘Keke Huang Changmin Hou Bin Hu Yixin Li Lei Chen 2012Procedia Engineering2012,,27:1
16A unique Janus PdZn-Co catalyst for enhanced photocatalytic syngas production from CO_(2) and H_(2)O显示文摘The development of excellent catalyst to achieve photocatalytic syngas production from CO_(2) and H_(2)O is a prospective and sustainable strategy to alleviate environment and energy crisis. In this study, a unique Janus PdZn-Co catalyst is prepared by annealed the Pd/IRMOF-3(Co, Zn) precursor. Due to the strong interaction, the electron transfers from PdZn terminal to Co terminal in the Janus structure. The electron-received Co terminal facilitates Co sites coordinate with the electrophilic C atom of CO_(2) and the electron-donated PdZn center is easier to coordinate with nucleophilic O atoms of H_(2)O or C=O bonds.The charge redistribution enhances the absorption of CO_(2) and H2O, which promotes H_(2) evolution and CO production. In addition, the carbon shell effectively suppresses the metal core agglomeration and facilitates the electron transmission from photosensitizer to metallic active sites. Meanwhile, the ratio of CO/H_(2) can be regulated(~3:1 to 2:1) by adjusting the proportion of Co and PdZn. The Janus structure and graphite carbon synergistically play a profound impact on improving the photocatalytic performance.The optimized PdZn-Co catalyst exhibits a superior photocatalytic CO production rate(20.03 μmol/h) and the H_(2) generation rate(9.90 μmol/h) with a ratio of CO/H_(2)= 2.02.Dongxue Zhou Xiangdong Xue Qingjie Luan Liguo Zhang Baozhen Li Xing Wang Wenjun Dong Ge Wang Changmin Hou 2023Chinese Chemical Letters2023,34,7:0
17Bedding-parallel fractures in ultradeep tight sandstone reservoirs in Jurassic and Cretaceous of Yongjin Oil Field,Junggar Basin,China显示文摘Bedding-parallel fractures are fractures that are parallel to rock bedding structure planes and have been widely accepted as a key factor for oil and gas production in tight sandstone and shale reservoirs.However,the formation mechanisms of these parallel-bedding fractures are still under debate.In this study,bedding-parallel fractures in Yongjin Oil Field were analyzed using methods including core and microscopic observations,element geochemistry,and carbon and oxygen isotope analysis.Their origin and relations to reservoir quality,faults,and rock mechanical properties were examined.The discovery of bedding-parallel fractures in both the Upper Jurassic and Lower Cretaceous formations indicates that the BPFs are generated later than the early Cretaceous.The filling state of bedding-parallel fractures that with no bitumen and carbonate cement indicate that they formed after oil charging and carbonate cementation.The tensile fracture characteristics in core and thin section observa-tions,and the fact that overburden stress exceeds the pore pressure indicate that the bedding-parallel fractures were neither generated from tectonic compression nor over-pressure.The most likely generation mechanism is stress relief during core drilling under high in situ stress conditions.High in situ stress and low tensile strength lead to thinner fracture spacing.The existence of high bedding-parallel fracture density is an indicator of good reservoir quality and result in high oil/gas production.Hongping LIU Changmin ZHANG Li ZHANG Yang LUO 2022Frontiers of Earth Science2022,16,4:0
18Radiative-coupled evaporative cooling:Fundamentals,development,and applications显示文摘As global energy demand continues to rise and climate change accelerates,the need for sustainable and energy-efficient cooling solutions has reached a critical level.Conventional air conditioning systems heavily rely on energy-intensive mechanical cooling,which significantly contributes to both electricity demand and greenhouse gas emissions.Passive cooling strategies,particularly radiative cooling(RC)and evaporative cooling(EC),present an alternative approach by harnessing natural processes for temperature regulation.While standalone RC can be affected by weather conditions and EC relies on water availability,Radiative-coupled EC(REC)offers a versatile and sustainable cooling solution suitable for various applications.Here we summarize an overview of the theoretical foundations and mathematical models of REC,encompassing REC by bulk water(REC-BW),REC by perspiration(REC-P),and REC by sorbed water(REC-SW).Moreover,we explore a range of applications,spanning from industrial processes to personal thermal management,and examine the advantages and challenges associated with each REC approach.The significance of REC lies in its potential to revolutionize cooling technology,reduce energy consumption,and minimize the environmental impact.REC-BW can conserve water resources in industrial cooling processes,while REC-P offers innovative solutions for wearable electronics and textiles.REC-SW’s adaptability makes it suitable for food preservation and future potable cooling devices.By addressing the challenges posed by REC,including water consumption,textile design,and optimization of bilayer structures,we can unlock the transformative potential of REC and contribute to sustainable cooling technologies in a warming world.Li Yu Yimou Huang Weihong Li Changmin Shi Brian W.Sheldon Zhuo Chen Meijie Chen 2024Nano Research Energy2024,3,2:0
19Ultrasensitive detection of IgE levels based on magnetic nanocapturer linked immunosensor assay for early diagnosis of cancer显示文摘Rapid and accurate detection of immunoglobulin E(Ig E) in serum and reduction of serum dosage are of great significance for clinical detection. Herein, we described a rapid magnetic separation of Ig E from patient serum based on Fe3 O4@Si O2-NTA@026 sdab as the capture probe and multiple horseradish peroxidase(HRP)-labeled antibodies linked gold nanoparticles(Au NPs) as chemiluminescence(CL) signal amplifier for ultrasensitive detection of total Ig E. Results showed that the limit of detection of our immunosensor system in serum samples was 0.03 k U/L, which is lowest in comparison with current methods, and far lower than that of Immuno CAP for Ig E detection(0.1 k U/L). Furthermore, our immunosensor possessed satisfied repeatability and accuracy, as well as good stability. In comparison with the Immuno CAP for the quantitative detection of Ig E, highly consistent results were achieved in 20 serum samples. Specially, this method was also successfully utilized for assessing the Ig E traces in breast cancer patients,which provides a new idea for the diagnosis of early cancer. Therefore, we believe that such versatile immunosensor will offer an alternative method for the on-site monitoring and determination of various Ig E-related diseases.Yongxin Liu Mengda Cao Zhongxi Huang Changmin Yu Naidi Yang Qiong Wu Liang Shi Wenjie Duan Yi Zhu Jifu Wei Lin Li Wei Huang 2022Chinese Chemical Letters2022,33,4:0
20United Nations and Human Rights显示文摘Charter and Universal Declaration Human rights problem has aroused serious concem from the international community. It was originated in the Second World War. Fascists of Germany, Italy and Japan committed genocide and crimes of killing innocents and it became a matter of worldwide concem to defend the right to life. The war between the anti-fascist alliance against the axis powers including Germany and Japan was in fact a war of protecting the dignity and rights of humanity and a war to defend human rights and for national independence. The programmatic document Charter of the Atlantic of the alliance during the war and the Declaration of the United Nations all clearly put forward the idea that defending human rightsLI TIECHENG AND LIU CHANGMIN 2002The Journal of Human Rights2002,1,3:0
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