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| 1 | Changes in sea ice kinematics in the Arctic outflow region and their associations with Arctic Northeast Passage accessibility显示文摘Amplification of climate warming in the Arctic is causing a dramatic retreat of sea ice, which means the Arctic sea routes are becoming increasingly accessible. This study used a satellite-derived sea ice motion product to quantify the kinematic features of sea ice in the Arctic outflow region which specially referred to the Fram Strait and to the north of the Northeast Passage(NEP). An observed trend of increased southward sea ice displacement from the central Arctic to the Fram Strait indicated enhancement of the Transpolar Drift Stream(TDS). In the regions to the north of the NEP, the long-term trend of northward sea ice speed in the Kara sector was +0.04 cm/s per year in spring. A significant statistical relationship was found between the NEP open period and the northward speed of the sea ice to the north of the NEP. The offshore advection of sea ice could account for the opening of sea routes by 33% and 15% in the Kara and Laptev sectors, respectively. The difference in sea level pressure across the TDS,i.e., the Central Arctic Index(CAI), presented more significant correlation than for the Arctic atmospheric Dipole Anomaly index with the open period of the NEP, and the CAI could explain the southward displacement of sea ice toward the Fram Strait by more than 45%. The impact from the summer positive CAI reinforces the thinning and mechanical weakening of the sea ice in the NEP region, which improves the navigability of the NEP. | Dawei Gui Xiaoping Pang Ruibo Lei Xi Zhao Jia Wang | 2019 | Acta Oceanologica Sinica2019，38，8： | 5 |
| 2 | Generation and characterization of stable pig pregastrulation epiblast stem cell lines显示文摘Pig epiblast-derived pluripotent stem cells are considered to have great potential and broad prospects for human therapeutic model developme nt and livestock breeding.Despite on going attempts since the 1990s,no stably defined pig epiblast-derived stem cell line has bee n established.Here,guided by in sights from a large-scale sin gle-cell tran scriptome an alysis of pig embryos from embryonic day(E)0 to E14,specifically,the tracing of pluripotency changes during epiblast development,we developed an in vitro culture medium for establishing and maintaining stable pluripotent stem cell lines from pig E10 pregastrulation epiblasts(pgEpiSCs).Enabled by chemical inhibition of WNT-related signaling in combination with growth factors in the FGF/ERK,JAK/STAT3,and Activin/Nodal pathways,pgEpiSCs maintain their pluripotency transcriptome features,similar to those of E10 epiblast cells,and normal karyotypes after more than 240 passages and have the potential to differentiate into three germ layers.Strikingly,ultradeep in situ Hi-C analysis revealed functional impacts of chromatin 3D-spatial associations on the transcriptional regulation of pluripote ncy marker genes in pgEpiSCs.I n practice,we con firmed that pgEpiSCs readily tolerate at least three rounds of successive gene editi ng and gene rated cloned gen e-edited live piglets.Our findings deliver on the long-a nticipated promise of pig pluripote nt stem cells and open new avenues for biological research,animal husbandry,and regenerative biomedicine. | Minglei Zhi Jinying Zhang Qianzi Tang Dawei Yu Shuai Gao Dengfeng Gao Pengliang Liu Jianxiong Guo Tang Hai Jie Gao Suying Cao Zimo Zhao Chongyang Li Xiaogang Weng Mengnan He Tianzhi Chen Yingjie Wang Keren Long Deling Jiao Guanglei Li Jiaman Zhang Yan Liu Yu Lin Daxin Pang Qianqian Zhu Naixin Chen Jingjing Huang Xinze Chen Yixuan Yao Jingcang Yang Zicong Xie Xianya Huang Mengxin Liu Ran Zhang Qiuyan Li Yiliang Miao Jianhui Tian Xingxu Huang Hongsheng Ouyang Bofeng Liu Wei Xie Qi Zhou Zhonghua Liu Caihong Zheng Mingzhou Li Jianyong Han | 2022 | Cell Research2022，32，4： | 3 |
| 3 | Provenance of Lower Carboniferous Bauxite Deposits in Northern Guizhou,China:Constraints from Geochemistry and Detrital Zircon U-Pb Ages显示文摘The Lower Carboniferous Jiujialu Formation bauxite deposits of northern Guizhou Province,China,are a Kazakhstan subtype of karst bauxite deposits.The provenance of the Jiujialu Formation has long been debated,with uncertainty about the formation of the bauxite deposits.Here we report new geochemical data that indicate the affinity between the Lower-Middle Ordovician clastic rocks and argillaceous dolostones and the overlying Carboniferous bauxite deposits,all of which are characterized by high Al_(2)0_(3),K2_(O),and∑REE contents,flat post-Archean Australian shale(PAAS)-normalized REE patterns,and uniform immobile element ratios(TiO2/Al_(2)0_(3),Nb/TiO2,and Zr/TiO2).Their similar detrital zircon age distributions further indicate the link between the bauxite deposits and the clastic rocks and argillaceous dolostones.Zircon age spectra of clastic rocks of the Lower Silurian Hanchiatien Formation in northern Guizhou match those of the bauxite deposits,with a maximum age peak at-980 Ma and other secondary age peaks,suggesting these clastic rocks may represent the provenance of the bauxite deposits.The youngest detrital zircons(-445 Ma)occur only in the bauxite deposits and are probably sourced from K-bentonite beds of the Ordovician-Silurian tran-sition.Our analyses indicate that the source materials of the bauxite deposits in the Jiujialu Formation are of mixed provenance:Lower-Middle Ordovician aluminosilicate rocks and argillaceous dolostones of the underlying strata,and Lower Silurian clastic rocks and K-bentonite from adjacent areas.A comparison of Early Carboniferous bauxitic provenances in northern and central Guizhou indicates that paleotopography was the major factor controlling the provenance of these bauxite deposits. | Guolin Xiong Wenchao Yu Yuansheng Du Shenfu Weng Dawei Pang Xusheng Deng Jintao Zhou | 2021 | Journal of Earth Science2021，32，1： | 3 |
| 4 | Characterization of the unprecedented polynya events north of Greenland in 2017/2018 using remote sensing and reanalysis data显示文摘Based on an ice concentration threshold of 90%,it has been identified that two polynya events occurred in the region north of Greenland during the 2017/2018 ice season.The winter event lasted from February 20 to March 3,2018 and the summer event persisted from August 2 to September 5,2018.The minimum ice concentration derived from Advanced Microwave Scanning Radiometer 2(AMSR2)observations was 72%and 65%during the winter and summer events,respectively.The occurrence of both events can be related to strengthened southerly winds associated with an increased east-west zonal surface level air pressure gradient across the north Greenland due to perturbation of mid-troposphere polar vortex.The relatively warm air temperature during the 2017/2018 freezing season in comparison with previous years,together with the occurrence of the winter polynya,formed favourable pre-conditions for ice field fracturing in summer,which promoted the formation of the summer polynya.Diminished southerly winds and increased cover of new ice over the open water were the dominant factors for the disappearance of the winter polynya,whereas increased ice inflow from the north was the primary factor behind the closure of the summer polynya.Sentinel-1 Synthetic Aperture Radar(SAR)images were found better suited than AMSR2 observations for quantification of a new ice product during the polynya event because the SAR images have high potential for mapping of different sea ice regimes with finely spatial resolution.The unprecedented polynya events north of Greenland in 2017/2018 are important from the perspective of Arctic sea ice loss because they occurred in a region that could potentially be the last“Arctic sea ice refuge”in future summers. | Ruibo Lei Dawei Gui Zhouli Yuan Xiaoping Pang Ding Tao Mengxi Zhai | 2020 | Acta Oceanologica Sinica2020，39，9： | 3 |
| 5 | Rapid Microwave-Assisted Ionothermal Dissolution of Cellulose and Its Regeneration Properties显示文摘Introduction of the strategy of anhydrous calcium carbonate protection incorporated with the drop by drop reaction,high-purity 1-butyl-3-methylimidazolium chloride([Bmim]Cl)was prepared at reaction temperature of 80°C for only 10 h.Cellulose samples from different biomass sources(with different degree of polymerization characteristic)could be rapidly(no more than 10 minutes)and completely dissolved in the[Bmim]Cl using a microwave-assisted ionothermal route.Homogeneous cellulosic regenerates with high degree of polymerization and thermal stability characteristics were obtained through a coagulation process in water.Furthermore,the dissolved celluloses were readily regenerated into solid products such as casting films and spinning fibers,which exhibited high transparency and flexibility,as well as superior mechanical properties of over 300 MPa(tensile strength)more than those of cellulose samples reported.This study therefore provides a new process for the synthesis of high-purity[Bmim]Cl for the highly efficient dissolution of cellulose to produce high performance cellulosic materials for various applications such as flexible electronic,optoelectronic,soft robots. | Xu Wang Jianhong Zhou Bo Pang Dawei Zhao | 2019 | Journal of Renewable Materials2019，7，12： | 2 |
| 6 | Molecular Cloning and Bioinformatics Analysis of TypeⅢSecretion System Effector Protein Va1686 Gene of Vibrio alginolyticus显示文摘In this study,Va1686 gene was cloned from Vibrio alginolyticus. The total length of the gene is 1 164 bp,and it could encode 387 amino acids. The physicochemical properties,protein structure,genetic evolutionary relationship and antigenic characteristics of the effect protein Va1686 of V. alginolyticus HY9901 type Ⅲ secretion system were studied and analyzed by bioinformatics methods and tools. The results showed that Va1686 is a stable hydrophilic and acidic protein without a transmembrane region and a signal peptide,and secondary structure to α-helix. The evolutionary analysis showed that V. alginolyticus HY9901 and V.harveyi were clustered together,which indicated that the genetic relationship between the two species was the closest. Va1686 contains a Fic superfamily conserved domain associated with cell division. Bioinformatics analysis showed that the B-cell preponderant epitopes of Va1686 might be localized in the regions of 48-49,82-85,125-126,150-153,185-186,236-237 and so on. The 3D structure model of Va1686 subunit was simulated by SWISS-MODEL software and it was found that the vop S of V. parahaemolyticus was similar and the similarity was 89. 46%. In this study,the feasibility of Va1686 as a common antigen of Vibrio was verified from the perspective of bioinformatics,which laid the foundation for the next step in vaccine development. | Zhihao WU Mingjie FAN Jiaming LIAO Huanying PANG Chuanhao PAN Dawei SONG Mingsheng QIU Shuanghu CAI Jichang JIAN | 2018 | Agricultural Biotechnology2018，7，5： | 2 |
| 7 | Molecular Cloning and Bioinformatics Analysis of T3SS Effector HopPmaJ from Vibrio alginolyticus显示文摘In this paper,the hopPmaJ gene,which encodes type III effector HopPmaJ of Vibrio alginolyticus,was cloned,sequenced and bioinformatically predicted.The results showed that hopPmaJ(GenB ank accession number:KX245315)is 345 bp in length and encodes 114 amino acids,with a theoretical molecular mass of 12.774 kD,and a pI of 4.45.The protein has multiple functional domains and binding sites,but no signal peptide.The tertiary structure of the protein is a homodimer.Based on multiple parameters,the possible dominant B cell antigenic epitopes of HopPmaJ were predicted to be at positions 13-16,29-30,40-42,45-49 and 84-91. | Jingmin ZHAO Mingsheng QIU Huanying PANG Dawei SONG Yunsheng CHANG Yang HUANG Jichang JIAN | 2017 | Agricultural Biotechnology2017，6，4： | 1 |
| 8 | Towards safe lithium-sulfur batteries from liquid-state electrolyte to solid-state electrolyte显示文摘Lithium-sulfur(Li-S)battery has been considered as one of the most promising future batteries owing to the high theoretical energy density(2600 W-h-kg-1)and the usage of the inexpensive active materials(elemental sulfur).The recent progress in fundamental research and engineering of the Li-S battery,involved in electrode,electrolyte,membrane,binder,and current collector,has greatly promoted the performance of Li s batteries from the laboratory level to the approaching practical level.However,the safety concerns still deserve attention in the following application stage.This review focuses on the development of the electrolyte for Li S batteries from liquid state to solid state.Some problems and the corresponding solutions are emphasized,such as the soluble lithium polysulfides migration,ionic conductivity of electrolyte,the interface contact between electrolyte and electrode,and the reaction kinetics.Moreover,future perspectives of the safe and high-performance Li S batteries arealso introduced. | Zhiyuan Pang Hongzhou Zhang Lu Wang Dawei Song Xixi Shi Yue Ma Linglong Kong Lianqi Zhang | 2023 | Frontiers of Materials Science2023，17，1： | 0 |
| 9 | Asynchronous gain-scheduled control of deepwater drilling riser system with hybrid event-triggered sampling and unreliable communication显示文摘This paper investigates the recoil control of the deepwater drilling riser system with nonlinear tension force and energy-bounded friction force under the circumstances of limited network resources and unreliable communication.Different from the existing linearization modeling method,a triangle-based polytope modeling method is applied to the nonlinear riser system.Based on the polytope model,to improve resource utilization and accommodate random data loss and communication delay,an asynchronous gain-scheduled control strategy under a hybrid event-triggered scheme is proposed.An asynchronous linear parameter-varying system that blends input delay and impulsive update equation is presented to model the nonlinear networked recoil control system,where the asynchronous deviation bounds of scheduling parameters are calculated.Resorting to the Lyapunov-Krasovskii functional method,some solvable conditions of disturbance attenuation analysis and recoil control design are derived such that the resulting networked system is exponentially mean-square stable with prescribed H∞performance.The obtained numerical results verified that the proposed nonlinear networked control method can achieve a better recoil response of the riser system with less transmission data compared with the linear control method. | Na PANG Dawei ZHANG Shuqian ZHU | 2024 | Frontiers of Information Technology & Electronic Engineering2024，25，2： | 0 |
| 10 | Systematic evaluation of IgG responses to SARS-CoV-2 spike protein-derived peptides for monitoring COVID-19 patients显示文摘Serological tests play an essential role in monitoring and combating the COVID-19 pandemic.Recombinant spike protein(S protein),especially the S1 protein,is one of the major reagents used for serological tests.However,the high cost of S protein production and possible cross-reactivity with other human coronaviruses pose unavoidable challenges.By taking advantage of a peptide microarray with full spike protein coverage,we analyzed 2,434 sera from 858 COVID-19 patients,63 asymptomatic patients and 610 controls collected from multiple clinical centers.Based on the results,we identified several S protein-derived 12-mer peptides that have high diagnostic performance.In particular,for monitoring the IgG response,one peptide(aa 1148-1159 or S2-78)exhibited a sensitivity(95.5%,95%CI 93.7-96.9%)and specificity(96.7%,95%CI 94.8-98.0%)comparable to those of the S1 protein for the detection of both symptomatic and asymptomatic COVID-19 cases.Furthermore,the diagnostic performance of the S2-78(aa 1148-1159)IgG was successfully validated by ELISA in an independent sample cohort.A panel of four peptides,S1-93(aa 553-564),S1-97(aa 577-588),S1-101(aa 601-612)and S1-105(aa 625-636),that likely will avoid potential cross-reactivity with sera from patients infected by other coronaviruses was constructed.The peptides identified in this study may be applied independently or in combination with the S1 protein for accurate,affordable,and accessible COVID-19 diagnosis. | Yang Li Dan-yun La Qing Lei Zhao-wei Xu Feng Wang Hongyan Hou Lingyun Chen Jiaoxiang Wu Yan Ren Ming-liang Ma Bo Zhang Hong Chen Caizheng Yu Jun-biao Xue Yun-xiao Zheng Xue-ning Wang He-wei Jiang Hai-nan Zhang Huan Qi Shu-juan Guo Yandi Zhang Xiaosong Lin Zongjie Yao Pengfei Pang Dawei Shi Wei Wang Xiao Yang Jie Zhou Huiming Sheng Ziyong Sun Hong Shan Xionglin Fan Sheng-ce Tao | 2021 | Cellular & Molecular Immunology2021，18，3： | 0 |
| 11 | Research on Planning and Design of Landscape Nursery of Hohhot City in China Based on Quickbird Image显示文摘Based on Quickbird images, 1:1,000 topographic map, hydrologic data, soil distribution, regulation of plant diseases and insect pests, and materials of commonly used local tree species, 188.3 hm 2 of production land and 45.6 hm 2 of non production land have been divided on the land covering an area of 234 hm 2 . Production land has been divided into eight functional areas and non production land has been classified into five types. And 47 species have been planned in nursery seedlings area and Quickbird image has been well applied in the planning and design of landscape nursery. | LIU Tiedong XU Dawei GONG Wenfeng HU Yuandong ZHU Lei WU Yan PANG Ying | 2012 | Journal of Landscape Research2012，4，8： | 0 |
| 12 | Construction of Live Attenuated Vaccine against Vib- rio alginolyticus and the Evaluation on Its Immuno- protection Effect显示文摘Vibrio alginolyticus,a gram-negative bacterium has been described to be one of the most common and economically important aquatic pathogens of fish and shellfish. Vaccine immunization is an effective approach preventing V. alginolyticus infection. Attenuated vaccine stimulates systemic immune response in the host,but few attenuated vaccine against V. alginolyticus is available. The type III secretion system( T3SS),an important pathogenic factor of V. alginolyticus,is used by bacterial pathogens to inject effector proteins into the cytoplasm of their host cells. The T3 SS forms a structure called needle complex with a multi-ring base that spans the bacteria and a needle-like extension that protrudes several nanometers from the bacterial surface. vscO locates at the ' needle' site of T3 SS,playing the role of escorting the molecular chaperone and effector proteins into host cells and further inducing the death of host cells. In this paper,an in-frame deletion mutant of vscO was constructed using overlap PCR and homologous recombination technology combining with chloramphenicol( Cm) and sucrose screening. The LD50 changes of ZJ03ΔvscO mutant strains compared with the strain ZJ03 were examined in grouper( Epinephelus coioides). The ZJ03ΔvscO mutant showed about 150 times decrease in virulence in E. coioides compared with wide type ZJ03. After vaccination with ZJ03ΔvscO in E. coioides through injection and immersion,the specific antibody titers were markedly higher than that in the saline control group( P < 0. 05). The titers of injection and immersion group on the forth week reached the maximums at 1∶ 2 048 and 1∶ 128,respectively. The relative percentage survival( RPS) of injection group was 84%,while that in immersion group was 68%.These results indicate that the ZJ03ΔvscO of V. alginolyticus has a high immunogenicity,and can be used as live attenuated vaccine. In addition,RPS may be affected by vaccination and infection methods. This study can provide technical support for controlling fish diseases caused by V. alginolyticus. | Yuan Yonghong Pang Huanying Zhou Zejun Song Dawei Ding Yu Jian Jichang Wu Zaohe | 2016 | Animal Husbandry and Feed Science2016，8，2： | 0 |
| 13 | Molecular Cloning and Bioinformatics Analysis of kdpE Gene from Vibrio alginolyticus显示文摘The two-component regulatory system plays an important role in the growth and virulence of bacteria.In this study,the phosphate transcriptional regulatory protein (KdpE) gene of Vibrio alginolyticus strain HY9901 was cloned.Sequence analysis revealed that the length of kdp E gene is 732 bp and encodes a putative protein of 243 amino acids.The predicted molecular weight (MW) of Kdp E was 27.66 k D with an estimated p I of 5.01.Using SignalP 4.0 and TMHMM Server 2.0 software,it was predicted that the Kdp E protein was located in cytoplasm.It did not contain a signal peptide or a transmembranous region.A phylogenetic tree was constructed by MEGA 5.0 software,indicating that the Kdp E of V.alginolyticus had high genetic relationship with Vibrio campbellii and Vibrio parahaemolyticus.Using SWISS-MODEL work-space,the three-dimensional structures of conserved domain REC in the Kdp E was determined.These results can provide a basis for further studies on the two-component regulatory systems of V.alginolyticus. | Hong Shunhua Yang Fan Pang Huanying Zhang Yanfei Song Dawei Wang Zhiwen Lu Yishan Jian Jichang | 2016 | Animal Husbandry and Feed Science2016，8，5： | 0 |
| 14 | Analysis of Biological Activity and Immunogenicity of Extracellular Products from Streptococcus iniae显示文摘[Objectives] This study aimed to analyze the biological activity and immunogenicity of extracellular products from Streptococcus iniae. [Methods] S.iniae was incubated with brain heart infusion agar medium( BHIA + 4% calf serum) for 60 h. The bacterial liquid was rinsed with PBS,centrifuged,and filtered through microporous filtering film to collect extracellular products( ECPs). [Results]Extracellular proteinase( ECPase) of S. iniae exhibited amylase,protease,lecitinase,gelatinase,lipase activities and hemolytic activity but had no urease activity. EDTA,DTT and PMSF could reduce ECPase activity to 72. 4%,77. 6%and 72. 4%,respectively. Cu^(2+),Ca^(2+),K+and Mg^(2+)exhibited an inhibitory effect on ECPase activity,whereas Fe^(3+),Co^(2+)and Mn^(2+)could activate ECPase activity. ECPs had good heat stability and exhibited relatively high activities under alkaline conditions. The optimal temperature for ECPs was 55 ℃. Two-dimensional electrophoresis was performed to analyze the main protein of ECPs. The results indicated that there are 12 main bands of ECPs,and the molecular weights mainly ranged between 28-68 kD a. About 120 protein spots were detected,and the molecular weights mainly ranged between 26-95 kD a. The mouse anti-S. iniae was used for Western-blot analysis of ECPs,and the results showed that there were four proteins,with molecular weights of 26,37,95,and 97 kD a,respectively. The pathogenicity assay indicated that ECPs of S. iniae were highly pathogenic to tilapia. The mortality rate of tilapia was enhanced as the concentration of ECPs increased. [Conclusions] This study provided a certain theoretical basis for revealing the pathogenic mechanism of Streptococcus iniae. | Danling GUO Shihui ZHOU Siyao ZHENG Dawei SONG Xuli ZHANG Huanying PANG Peiwen WU Jichang JIAN Yang HUANG | 2018 | Agricultural Biotechnology2018，7，4： | 0 |
| 15 | Molecular Cloning and Bioinformatics Analysis of TypeⅢSecretion System Effector Protein HY 322 Gene of Vibrio alginolyticus显示文摘In this study,Hy322 gene was cloned from Vibrio alginolyticus.The total length of its gene was 969 bp,and it could encode 322 amino acids.The physicochemical properties,protein structure,genetic evolutionary relationship and antigenic characteristics of the effector protein Hy322 of V.alginolyticus HY9901 type Ⅲ secretion system were studied and analyzed by bioinformatics methods and tools.The results showed that Hy322 is an unstable hydrophilic and acidic protein without a transmembrane region and a signal peptide,and secondary structure to α-helix.The evolutionary analysis showed that V.alginolyticus HY9901 and V.harveyi were clustered together,which indicated that the genetic relationship between the two species was closest.HY322 contains a FliN super family conserved domain associated with Flagellar motor switch.Bioinformatics analysis showed that the B-cell preponderant epitopes of Hy322 might be localized in the regions of 32-33,100-102,138-140,215-216,235-238 and 246-249.The 3D structure model of Hy322 subunit was simulated by SWISS-MODEL software and itwas found that the yscQ of Yersinia were similar and the similarity was 42.25%.In this study,the feasibility of Hy322 as a common antigen of Vibrio was verified from the perspective of bioinformatics,which laid the foundation for the next step in vaccine development. | Shanshan LIANG Mingjie FAN Weijian LIANG Huanying PANG Chuanhao PAN Dawei SONG Mingsheng QIU Jichang JIAN | 2018 | Agricultural Biotechnology2018，7，6： | 0 |
| 16 | Molecular Cloning and Bioinformatics Analysis of kdpD Gene from Vibrio alginolyticus显示文摘In this study,histidine kinase gene kdpD in the two-component regulatory system of Vibrio alginolyticus strain HY9901 was cloned for bioinformatics analysis. Sequence analysis revealed that kdpD gene( GenB ank accession number: KJ544668) was 1 374 bp in length,encoding a putative protein of 457 amino acids. The predicted molecular weight( MW) of KdpE was 51. 60 kD with a theoretical isoelectric point( pI) of 6. 02. Using SignalP 4. 0,TMHMM Server 2. 0 and SoftB erry-Psite software,it was predicted that KdpE protein was equally located in Golgi apparatus,plasma membrane and endoplasmic reticulum( 33. 3%),which did not contain a signal peptide but contained three transmembrane domains. KdpE protein had five casein kinase II phosphorylation sites,five protein kinase C phosphorylation sites and one cA MP- and cG MP-dependent protein kinase phosphorylation site. A phylogenetic tree was constructed by MEGA 5. 0 software,which revealed that KdpD from V. alginolyticus had close genetic relationship with corresponding proteins from V. campbellii and V. parahaemolyticus. Using SWISSMODEL Workspace,the three-dimensional structure of HATPase_c conserved domain in KdpD protein was constructed. These results may provide the basis for further studies on two-component regulatory system KdpD/KdpE of V. alginolyticus. | Haitao LIU Fan YANG Huanying PANG Yanfei ZHANG Dawei SONG Shuhe CHEN Ganlin WU Jichang JIAN | 2016 | Agricultural Biotechnology2016，5，3： | 0 |
| 17 | Disturbing cytoskeleton by engineered nanomaterials for enhanced cancer therapeutics显示文摘Cytoskeleton plays a significant role in the shape change,migration,movement,adhesion,cytokinesis,and phagocytosis of tumor cells.In clinical practice,some anti-cancer drugs achieve cytoskeletal therapeutic effects by acting on different cytoskeletal protein components.However,in the absence of cell-specific targeting,unnecessary cytoskeletal recombination in organisms would be disastrous,which would also bring about severe side effects during anticancer process.Nanomedicine have been proven to be superior to some small molecule drugs in cancer treatment due to better stability and targeting,and lower side effects.Therefore,this review summarized the recent developments of various nanomaterials disturbing cytoskeleton for enhanced cancer therapeutics,including carbon,noble metals,metal oxides,black phosphorus,calcium,silicon,polymers,peptides,and metal-organic frameworks,etc.A comprehensive analysis of the characteristics of cytoskeleton therapy as well as the future prospects and challenges towards clinical application were also discussed.We aim to drive on this emerging topic through refreshing perspectives based on our own work and what we have also learnt from others.This review will help researchers quickly understand relevant cytoskeletal therapeutic information to further advance the development of cancer nanomedicine. | Xueli Xu Shanbin Xu Jipeng Wan Diqing Wang Xinlong Pang Yuan Gao Nengyi Ni Dawei Chen Xiao Sun | 2023 | Bioactive Materials2023，，11： | 0 |
| 18 | Dynamical investigation of tunable magnetism in Au@Ni-carbide nanocrystals by a combined soft and hard X-ray absorption spectroscopy显示文摘Nickel based magnetic nanocrystals have been widely applied in magnetic and catalytic facilities.Tunable magnetic properties of nickel can be easily obtained via non-magnetic doping or phase transformation.However,phase transformation from face centered cubic(fcc)to hexagonal close packed(hcp)induced magnetism adjustment of Ni are always confused with nickel carbide(Ni_(3)C),due to the similar atomic structures of hcp-Ni and Ni3C.Here,we present series of Au@Ni-carbide magnetic materials achieved from the controlled carbonation of Au@Ni core-shell structures,whose magnetism is tunable by adjusting the amount of carbon in the Ni layer.Ex-situ hard X-ray absorption spectroscopy(XAS)at the metal K edge and soft XAS at both metal L edge and carbon K edge provide solid evidence for the carbonation process from fcc-Ni to Ni_(x)C,rather than phase transformation to hcp-Ni.Further investigation reveals that the magnetism of the hybrids is mainly contributed from the residual fcc-Ni.The result represents an accurate and effective way to distinguish hexagonal Ni_(3)C from hcp-Ni,and provides the pathway to control magnetism of Ni-based materials for applications. | Weifeng Huang Jianxin Kang Tingwen Chen Dawei Pang Lihua Wang Hang Wei Changchun Yang Dongfeng Zhang Lin Guo | 2022 | Nano Research2022，15，5： | 0 |
| 19 | Highly efficient and recyclable amorphous Pd(II)/crystal Pd(0)catalyst for boosting Suzuki reaction in aqueous solution显示文摘Ultrafine and highly dispersed Pd nanoparticles have drawn considerable attention with high activity,selectivity and atomic efficiency.In this paper,amorphous Pd(II)-complex solid spheres with-5 nm Pd nanoparticles loaded on were successfully achieved through a simple and gentle one-pot solution method with vitamin B1 simultaneously as complexing agent and reducing agent.An ultrathin mesoporous SiO_(2) shell was then coated at the surface of Pd(II-O)spheres as the armor which could prevent the dissolution of Pd(II)during the catalytic process.The combination of Pd(II)and Pd(0)endowed Pd(II-0)@m-SiO_(2) catalyst an excellent performance in eco-friendly aqueous media Suzuki reactions.The high activity,productivity and recyclability were all comparable with the best Pd catalysts ever reported.The ingenious formation of amorphous Pd(II)/crystal Pd(0)with enhanced catalytic performances provides a new,scalable strategy to practical promotion of Suzuki cross-coupling reactions. | Yong Zhao Zhongning Huang Lianmeng Wang Xiangyu Chen Yan Zhang Xiuqin Yang Dawei Pang Jianxin Kang Lin Guo | 2022 | Nano Research2022，15，2： | 0 |
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