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| 1 | Cropland redistribution to marginal lands undermines environmental sustainability显示文摘Cropland redistribution to marginal land has been reported worldwide;however,the resulting impacts on environmental sustainability have not been investigated sufficiently.Here we investigated the environmental impacts of cropland redistribution in China.As a result of urbanization-induced loss of high-quality croplands in south China(~8.5 t ha^(-1)),croplands expanded to marginal lands in northeast(~4.5 t ha^(-1)) and northwest China(~2.9 t ha^(-1)) during 1990-2015 to pursue food security.However,the reclamation in these low-yield and ecologically vulnerable zones considerably undermined local environmental sustainability,for example increasing wind erosion(+3.47%),irrigation water consumption(+34.42%),fertilizer use(+20.02%) and decreasing natural habitats(-3.11%).Forecasts show that further reclamation in marginal lands per current policies would exacerbate environmental costs by 2050.The future cropland security risk will be remarkably intensified because of the conflict between food production and environmental sustainability.Our research suggests that globally emerging reclamation of marginal lands should be restricted and crop yield boost should be encouraged for both food security and environmental benefits. | Wenhui Kuang Jiyuan Liu Hanqin Tian Hao Shi Jinwei Dong Changqing Song Xiaoyong Li Guoming Du Yali Hou Dengsheng Lu Wenfeng Chi Tao Pan Shuwen Zhang Rafiq Hamdi Zherui Yin Huimin Yan Changzhen Yan Shixin Wu Rendong Li Jiuchun Yang Yinyin Dou Wenbin Wu Liqiao Liang Bao Xiang Shiqi Yang | 2022 | National Science Review2022，9，1： | 13 |
| 2 | Continuous land cover change monitoring in the remote sensing big data era显示文摘Since the late 20th century,global change issues have attracted lots of attention.As a key component of global changes,land cover and land use information has been increasingly important for improved understanding of global environmental changes and feedbacks between social and environmental systems(Verburg et al.,2015).A set of national and global scale land cover/use products with higher spatial and temporal resolutions have been developed to fill this gap.In China,existing efforts include China’s | DONG JinWei KUANG WenHui LIU JiYuan | 2017 | Science China Earth Sciences2017，60，12： | 13 |
| 3 | Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event. | TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，3： | 12 |
| 4 | Procalcitonin could be a reliable marker in differential diagnosis of post-implantation syndrome and infection after percutaneous endovascular aortic repair显示文摘 | Xue Ling Luo Songyuan Luo Jianfang Liu Zhen Gu Mengnan Kang Huiyuan Yang Fan Nie Bingrong Liu Yuan Huang Wenhui Xie Nianjin He Pengcheng Dong Haojian Ni Zhonghan Fan Ruixin Chen Jiyan | 2014 | Chinese Medical Journal2014，，14： | 8 |
| 5 | High-Resolution Genome-wide Association Study Identifies Genomic Regions and Candidate Genes for Important Agronomic Traits in Wheat显示文摘Wheat(Triticum aestivum)is a major staple food crop worldwide.Genetic dissection of important agronomic traits is essential for continuous improvement of wheat yield to meet the demand of the world's growing population.We conducted a large-scale genome-wide association study(GWAS)using a panel of 768 wheat cultivars that were genotyped with 327609 single-nucleotide polymorphisms generated by genotyping-by-sequencing and detected 395 quantitative trait loci(QTLs)for 12 traits under 7 environments.Among them,273 QTLs were delimited to≤1.0-Mb intervals and 7 of them are either known genes(Rht-D,Vrn-B1,and Vrn-D1)that have been cloned or known QTLs(TaGA2ox8,APO1,TaSus1-7B,and Rht12)that were previously mapped.Eight putative candidate genes were identified for three QTLs that enhance spike seed setting and grain size using gene expression data and were validated in three bi-parental populations.Protein sequence analysis identified 33 putative wheat orthologs that have high identity with rice genes in QTLs affecting similar traits.Large r^2 values for additive effects observed among the QTLs for most traits indicated that the phenotypes of these identified QTLs were highly predictable.Results from this study demonstrated that significantly increasing GWAS population size and marker density greatly improves detection and identification of candidate genes underlying a QTL,solidifying the foundation for large-scale QTL fine mapping,candidate gene validation,and developing functional markers for genomics-based breeding in wheat. | Yunlong Pang Chunxia Liu Danfeng Wang Paul St.Amand Amy Bernardo Wenhui Li Fang He Linzhi Li Liming Wang Xiufang Yuan Lei Dong Yu Su Huirui Zhang Meng Zhao Yunlong Liangi Hongze Jia Xitong Shen Yue Lu Hongming Jiang Yuye Wu Anfei Li Honggang Wang Lingrang Kong Guihua Bai Shubing Liu | 2020 | Molecular Plant2020，13，9： | 8 |
| 6 | Fibrinolytic Evaluation of Compounds Isolated from a Marine Fungus Stachybotrys Iongispora FG216显示文摘 | Ruihua Guo Yiting Zhang Dong Duan Qiang Fu Xiangyu Zhang Xiaowei Yu Shujun Wang Bin Bao Wenhui Wu | 2016 | Chinese Journal of Chemistry2016，34，11： | 4 |
| 7 | Assessment of the risk of infectious aerosols leaking to the environment from BSL-3 laboratory HEPA air filtration systems using model bacterial aerosols显示文摘To assess the risk of infectious bacterial aerosols leaking to the environment, the filtration efficiency of a biosafety level 3(BSL-3) laboratory high-efficiency particulate(HEPA) filter was investigated using the aerosolized bacteria Serratia marcescens. The aerosol size was measured using an Andersen sampler. Eight first stage HEPA filters(numbered 1-8) were distributed in contaminated labs and exhausts from each0f the first stage HEPA filters were aggregated and filtered through one second stage HEPA filter before being released to the environment. In total, 8 first-stage and 1 second-stage HEPA filters from the BSL-3 air purification system were analyzed. No S. marcescens was detected in first stage filters 1,2,4,5,7 and 8 and the second stage HEPA filter. The filtration efficiencies against aerosolized S. marcescens were >99.9999%.First stage filter numbers 3 and 6 had filtration efficiencies of 99.9825% and 99.9906%, respectively. When filter number 3 was replaced by a new filter and the bracket for filter number 6 was sealed, no aerosolized S. marcescens was detected in the filtered air. Our work suggests that the BSL-3 laboratory HEPA filter air purification system is effective against bacterial aerosols, with little to no bacterial leakage into the environment. | Zhanbo Wen Wenhui Yang Na Li Jie Wang Lingfei Hu Jinsong Li Zhe Yin Ke Zhang Xiaokai Dong | 2014 | Particuology2014，12，2： | 2 |
| 8 | Homing and differentiation of mesenchymal stem cells delivered intravenously to ischemic myocardium in vivo: a time-series study显示文摘 | Wenhui Jiang Aiqun Ma Tingzhong Wang Ke Han Yu Liu Yanmin Zhang Anping Dong Yuan Du Xin Huang Jun Wang Xinjun Lei Xiaopu Zheng | 2006 | Pflügers Archiv - European Journal of Physiology2006，，1： | 1 |
| 9 | Protein kinase A mediates glucagon - like peptide 1 - induced nitric oxide production and muscle microvascular recruitment 显示文摘 | DONG Zhenhua CHAI Weidong WANG Wenhui | 2013 | Am J Physiol Endocrinol Metab2013，304，2： | 1 |
| 10 | Degradation particles derived from high-purity magnesium inhibit osteogenic differentiation through regulation of macrophage polarization显示文摘Magnesium(Mg)and its alloys have great potential as orthopedic implant candidates,which could release various bioactive substances during degradation.Degradation particles(DPs)are one of the degradation products,but the osteoimmunology effects are still unclear.In this study,the effect of DPs on the polar-ization of macrophages and their release of cytokines was investigated.The results verify that excessive generation of DPs from biodegradable Mg can induce macrophages to realize polarization of proinflamma-tory M1 phenotype.Moreover,macrophages secrete proinflammatory cytokines to inhibit the osteogenic differentiation of rat bone marrow stem cells(rBMSCs).This suggests that the effects of DPs should be considered when evaluating Mg-based implants.DPs continuously produced with the degradation of Mg-based implants may influence osseointegration. | Yu Sun Han Yu Hongzhou Peng Xinbao Kang Zhaoxiang Peng Xieping Dong Wenhui Wang Yang Song Xiaonong Zhang | 2023 | Journal of Materials Science & Technology2023，，8： | 1 |
| 11 | Partner selection and optimization model in global manufacturing显示文摘 | DONG Wenhui GONG Yadong WANG Wanshan | 2005 | Journal of Northeastern University2005，26，5： | 1 |
| 12 | Establishment of an experimental human lung adenocarcinoma cell line SPC-A-1BM with high bone metastases potency by 99m Tc-MDP bone scintigraphy显示文摘 | Shunfang Yang Qianggang Dong Ming Yao Meiping Shi Jianding Ye Langxiang Zhao Jianzhong Su Weiyong Gu Wenhui Xie Kankan Wang Yanzhi Du Yao Li Yan Huang | 2009 | Nuclear Medicine and Biology2009，，3： | 1 |
| 13 | Scheduling strategy for network-based multi-camera relay tracking in large scene显示文摘 | Chang Faliang Dong Wenhui Li Jiangbao | 2013 | Journal of Computational Information Systems2013，9，1： | 1 |
| 14 | Design and fabrication of superconducting transition edge sensor bolometers with background limited noise performance显示文摘We successfully designed and fabricated TES bolometers utilizing Al/Ti bilayer TESs as sensitive thermometers.To reduce the intrinsic noise level and tune the saturation power of a bolometer,the TES thermometer is placed on a suspended SiN platform which is thermally coupled to the heat bath by four long SiN beams with different geometries.The measurement results show that the detectors have background limited noise performance,with a low noise equivalent power(NEP)on the order of10-17W/Hz1/2and have a saturation power of several tens pW at a bath temperature of 320 mK.These detectors are suitable for applications in ground-based astrophysics experiments by integrating absorbers for specific wavelengths. | Qingya Zhang Jianshe Liu Wenhui Dong Tianshun Wang Genfang He Tiefu Li Xingxiang Zhou Wei Chen | 2014 | Chinese Science Bulletin2014，59，19： | 1 |
| 15 | Si/ PEDOT hybrid core/shell nanowire arrays as photoelectrodes for photoelectrochemical water- splitting显示文摘 | Li Xiaojuan Lu Wenhui Dong Weiling | 2013 | Nanoscale2013，5，12： | 1 |
| 16 | Part- ner selection and optimization model in global manufactur- ing 显示文摘 | DONG Wenhui GONG Yadong WANG Wanshan | 2005 | Journal of Northeastern University2005，26，5： | 1 |
| 17 | Albumin-induced premature senescence in human renal proximal tubular cells and its relationship with intercellular fibrosis显示文摘The presence of senescent cells is associated with renal fibrosis.This study aims to investigate the effect of albumininduced premature senescence on tubulointerstitial fibrosis and its possible mechanism in vitro.Different concentrations of bovine serum albumim(BSA)with or without si-p21 are used to stimulate HK-2 cells for 72 h,and SA-β-gal activity,senescence-associated secretory phenotypes(SASPs),LaminB1 are used as markers of senescence.Immunofluorescence staining is performed to characterize the G2/M phase arrest between the control and BSA groups.Alterations in the DNA damage markerγ-H2AX,fibrogenesis,and associated proteins at the G2/M phase,such as p21,p-CDC25C and p-CDK1,are evaluated.Compared with those in the control group,the SA-β-gal activity,SASP,andγ-H2AX levels are increased in the BSA group,while the level of LaminB1 is decreased.Meanwhile,HK-2 cells blocked at the G2/M phase are significantly increased under the stimulation of BSA,and the levels of p21,p-CDC25C and p-CDK1,as well as fibrogenesis are also increased.When p21 expression is inhibited,the levels of p-CDC25C and p-CDK1 are decreased and the G2/M phase arrest is improved,which decreases the production of fibrogenesis.In conclusion,BSA induces renal tubular epithelial cell premature senescence,which regulates the G2/M phase through the CDC25C/CDK1 pathway,leading to tubulointerstitial fibrosis. | Wen Lu Shijing Ren Wenhui Dong Xiaomin Li Zongji Zheng Yijie Jia Yaoming Xue | 2022 | Acta Biochimica et Biophysica Sinica2022，54，7： | 1 |
| 18 | The studies of PLGA nanoparticles loading atorvastatin calcium for oral administration in vitro and in vivo显示文摘A biodegradable poly(lactic-co-glycolic acid) loading atorvastatin calcium(AC) nanoparticles(AC-PLGA-NPs) were prepared by probe ultrasonication and evaporation method aiming at improving the oral bioavailability of AC. The effects of experimental parameters, including stabilizer species, stabilizer concentration and pH of aqueous phase, on particle size were also evaluated. The resultant nanoparticles were in spherical shape with an average diameter of 174.7 nm and a narrow particle size distribution. And the drug loading and encapsulation efficiency were about 8% and 71%, respectively. The particle size and polydispersion were almost unchanged in 10 days. The release curves of AC-PLGA-NPs in vitro displaying sustained release characteristics indicated that its release mechanisms were matrix erosion and diffusion. The pharmacokinetic study in vivo revealed that the Cmax and AUC0-∞ of AC-PLGA-NPs in rats were nearly 3.7-fold and 4.7-fold higher than that of pure atorvastatin calcium suspension. Our results demonstrated that the delivery of AC-PLGANPs could be a promising approach for the oral delivery of AC for enhanced bioavailability. | Zhenbao Li Wenhui Tao Dong Zhang Chunnuan Wu Binbin Song Shang Wang Tianyang Wang Mingming Hu Xiaohong Liu Yongjun Wang Yinghua Sun Jin Sun | 2017 | Asian Journal of Pharmaceutical Sciences2017，12，3： | 1 |
| 19 | Re- mediation of soil co-contaminated with petroleum and heavy metals by the integration of electrokinetics and biostimulation 显示文摘 | DONG Zhiyong HUANG Wenhui XING Dingfeng | 2013 | Journal of Hazardous Materials2013，260，9： | 1 |
| 20 | An air-stable supported Cu(?) catalyst for azide-alkyne click polymerization显示文摘An air-stable supported Cu(I) catalyst, Cu I@PS-Phen, was designed and synthesized. Cu I@PS-Phen can efficiently catalyze the click polymerization of diynes a and diazides b to produce soluble and thermally stable polytriazoles with high molecular weights(Mw up to 30800), and low copper residue content(down to 190 ppm) in high yields(up to 94.2%) under mild reaction conditions without the exclusion of oxygen. | Haiqiang Wu Wenhui Dong Zongtan Wang Bicheng Yao Ming Chen Jingzhi Sun Anjun Qin Ben Zhong Tang | 2015 | Science China Chemistry2015，58，11： | 0 |
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