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| 1 | How many sutures in the southern Central Asian Orogenic Belt:Insights from East Xinjiang-West Gansu(NW China)?显示文摘How ophiolitic mèlanges can be defined as sutures is controversial with regard to accretionary orogenesis and continental growth.The Chinese Altay,East junggar,Tianshan,and Beishan belts of the southern Central Asian Orogenic Belt(CAOB) in Northwest China,offer a special natural laboratory to resolve this puzzle.In the Chinese Altay,the Erqis unit consists of ophiolitic melanges and coherent assemblages,forming a Paleozoic accretionary complex.At least two ophiolitic melanges(Armantai,and Kelameili) in East Junggar,characterized by imbricated ophiolitic melanges,Nb-enriched basalts,adakitic rocks and volcanic rocks,belong to a Devonian-Carboniferous intra-oceanic island arc with some Paleozoic ophiolites,superimposed by Permian arc volcanism.In the Tianshan,ophiolitic melanges like Kanggurtag,North Tianshan,and South Tianshan occur as part of some Paleozoic accretionary complexes related to amalgamation of arc terranes.In the Beishan there are also several ophiolitic melanges,including the Hongshishan,Xingxingxia-Shibangjing,Hongliuhe-Xichangjing,and Liuyuan ophiolitic units.Most ophiolitic melanges in the study area are characterized by ultramafic,mafic and other components,which are juxtaposed,or even emplaced as lenses and knockers in a matrix of some coherent units.The tectonic settings of various components are different,and some adjacent units in the same melange show contrasting different tectonic settings.The formation ages of these various components are in a wide spectrum,varying from Neoproterozoic to Permian.Therefore we cannot assume that these ophiolitic melanges always form in linear sutures as a result of the closure of specific oceans.Often the ophiolitic components formed either as the substrate of intra-oceanic arcs,or were accreted as lenses or knockers in subduction-accretion complexes.Using published age and paleogeographic constraints,we propose the presence of (1) a major early Paleozoic tectonic boundary that separates the Chinese Altay-East Junggar multiple subduction systems of the southern Siberian active margin from those of the northern Tarim;and (2) a major Permian suture zone that separates the Tianshan-Beishan from the northern active margin of the Tarim Craton.These new observations and interpretations have broad implications for the architecture and crustal growth of central Asia and other ancient orogens as well. | Wenjiao Xiao Chunming Han Wei Liu Bo Wan Ji'en Zhang Songjian Ao Zhiyong Zhang Dongfang Song Zhonghua Tian Jun Luo | 2014 | Geoscience Frontiers2014，5，4： | 31 |
| 2 | Inhibition of the B7-H3 immune checkpoint limits tumor growth by enhancing cytotoxic lymphocyte function显示文摘在肿瘤和免疫系统之间的相互作用仍然糟糕被理解。重要临床的回答在对 CTLA4 和 PD-1/PD-L1 检查点与抗体对待的癌症病人被完成了;然而,仅仅病人的小部分对治疗作出回应,显示需要探索为癌症治疗的另外的 co 禁止的分子。B7-H3, B7 总科的一个成员,被我们以前显示出禁止 T 房间激活和 autoimmunity。在这研究,我们在肿瘤免疫分析了 B7-H3 的功能。B7-H3 的表示在多重肿瘤线,渗入肿瘤的树枝状的房间,和巨噬细胞被发现。与对抗抗体对待到 B7-H3 的 B7-H3-deficient 老鼠或老鼠显示出多重肿瘤的减少的生长,它取决于 NK 和 CD8 + T 房间。与细胞毒素的淋巴细胞表示的通常认为的受体, B7-H3 禁止了他们的激活,并且它的缺乏在忍受肿瘤的鼠标导致了增加的细胞毒素的淋巴细胞功能。B7-H3 和 PD-1 的联合封锁导致了迟了阶段的肿瘤的进一步提高的治疗学的控制。一起拿,我们的结果显示 B7-H3 检查点可以对癌症为免疫疗法用作一个新奇目标。 | Young-hee Lee Natalia Martin-Orozco Peilin Zheng Jing Li Peng Zhang Haidong Tan Hyun Jung Park Mira Jeong Seon Hee Chang Byung-Seok Kim Wei Xiong Wenjuan Zang Li Guo Yang Liu Zhong-jun Dong Willem W Overwijk Patrick Hwu Qing Yi Larry Kwak Zhiying Yang Tak W Mak Wei-Li Laszlo G Radvanyi Ling Ni Dongfang Liu Chen Dong | 2017 | Cell Research2017，27，8： | 29 |
| 3 | METTL3-mediated N^6-methyladenosine mRNA modification enhances long-term memory consolidation显示文摘 | Zeyu Zhang Meng Wang Dongfang Xie Zenghui Huang Lisha Zhang Ying Yang Dongxue Ma Wenguang Li Qi Zhou Yun-Gui Yang Xiu-Jie Wang | 2018 | Cell Research2018，28，11： | 29 |
| 4 | A Road Extraction Method for Remote Sensing Image Based on Encoder-Decoder Network显示文摘According to the characteristics of the road features,an Encoder-Decoder deep semantic segmentation network is designed for the road extraction of remote sensing images.Firstly,as the features of the road target are rich in local details and simple in semantic features,an Encoder-Decoder network with shallow layers and high resolution is designed to improve the ability to represent detail information.Secondly,as the road area is a small proportion in remote sensing images,the cross-entropy loss function is improved,which solves the imbalance between positive and negative samples in the training process.Experiments on large road extraction datasets show that the proposed method gets the recall rate 83.9%,precision 82.5%and F1-score 82.9%,which can extract the road targets in remote sensing images completely and accurately.The Encoder-Decoder network designed in this paper performs well in the road extraction task and needs less artificial participation,so it has a good application prospect. | Hao HE Shuyang WANG Shicheng WANG Dongfang YANG Xing LIU | 2020 | Journal of Geodesy and Geoinformation Science2020，3，2： | 20 |
| 5 | Accretionary processes and metallogenesis of the Central Asian Orogenic Belt:Advances and perspectives显示文摘As one of the largest Phanerozoic orogens in the world,the Central Asian Orogenic Belt(CAOB)is a natural laboratory for studies of continental dynamics and metallogenesis.This paper summarizes the research progresses of the accretionary processes and metallogenesis of the CAOB since the Peopled Republic of China was founded,and puts forward the prospect for future research.During the early period(1950s-1970s),several geological theories were applied to explain the geological evolution of Central Asia.In the early period of China's reform and opening-up,the plate tectonics theory was applied to explain the evolution of the northern Xinjiang and Xingmeng regions,and the opinion of subduction-collision between Siberian Kazakhstan and China-North Korea-Tarim plates was proposed.The idea of the Solonker-Yanbian suture zone was established.In the 1990s,the study of the CAOB entered a period of rapid development.One school of scholars including geologists from the former Soviet Union proposed a multi-block collision model for the assemblage of the CAOB.In contrast,another school of scholars,led by a Turkish geologist,Celal Sengor,proposed that the Altaids was formed through the growth and strike-slip duplicates of a single island arc,and pointed out that the Altaids is a special type of collisional orogen.During this period,Chinese geologists carried out a lot of pioneering researches on ophiolites and high-pressure metamorphic rocks in northern China,and confirmed the main suture zones accordingly.In 1999,the concept of'Central Asian metallogenic domain'was proposed,and it became one of the three major metallogenic domains in the world.Since the 21st century,given the importance for understanding continental accretion and metallogenic mechanism,the CAOB has become the international academic forefront.China has laid out a series of scientific research projects in Central Asia.A large number of important scientific research achievements have been spawned,including the tectonic attribution of micro-continents,timing and tectonic settings of ophiolites,magmatic arcs,identification and anatomy of accretionary wedges,regional metamorphism-deformation,(ultra)high-pressure metamorphism,ridge subduction plume-plate interaction archipelagic paleogeography and spatio-temporal framework of multiple accretionary orogeny,continental growth accretionary metallogenesis,structural superposition and transformation etc.These achievements have made important international influences.There still exist the following aspects that need further study:(1)Early evolution history and subduction initiation of the Paleo-Asian Ocean;(2)The accretionary mechanism of the extroversion Paleo-Asian Ocean;(3)The properties of the mantle of the Paleo-Asian Ocean and their spatiotemporal distribution;(4)The interaction between the Paleo-Asian Ocean and the Tethys Ocean;(5)Phanerozoic continental growth mechanism and its global comparison;(6)Accretionary metallogenic mechanism of the Central Asian metallogenic domain;and(7)Continental transformation mechanism. | Wenjiao XIAO Dongfang SONG Brian FWINDLEY Jiliang LI Chunming HAN Bo WAN Ji'en ZHANG Songjian AO Zhiyong ZHANG | 2020 | Science China Earth Sciences2020，63，3： | 16 |
| 6 | Lightning Activity and Its Relation to the Intensity of Typhoons over the Northwest Pacific Ocean显示文摘Data from the World Wide Lightning Location Network(WWLLN) were used to analyze the lightning activity and the relationship between maximum sustained wind and lightning rate in 69 tropical cyclones over the Northwest Pacific Ocean from 2005 to 2009. The minimum lightning density was observed in the category 2 typhoon Kong-Rey(2007), with a value of only 1.15 d-1(100 km)-2. The maximum lightning density occurred in the category 2 typhoon Mitag(2007), with a value of 510.42 d-1(100 km)-2. The average lightning density decreased with radius from the typhoon center in both weak(categories 1–3) and super(categories 4–5) typhoons. The average lightning density in the inner core of super typhoons was more than twice as large as that for weak typhoons. Both groups of typhoons showed a near-monotonic decrease in lightning density with radius. Results also showed that lightning activity was more active in typhoons that made landfall than in those that did not. The mean correlation coefficient between the accumulated flashes within a 600-km radius and the maximum wind speed in the weak typhoons and super typhoons was 0.81 and 0.74, respectively. For more than 78%(56%) of the super(weak) typhoons, the lightning activity peaked before the maximum sustained wind speed, with the most common leading time being 30(60) h. The results suggest that, for the Northwest Pacific Ocean, lightning activity might be used as a measurement of the intensification of typhoons. | PAN Lunxiang QIE Xiushu WANG Dongfang | 2014 | Advances in Atmospheric Sciences2014，31，3： | 12 |
| 7 | Chimeric antigen receptor (CAR)-modified natural killer cell-based immunotherapy and immunological synapse formation in cancer and HIV显示文摘 | Dongfang Liu Shuo Tian Kai Zhang Wei Xiong Ndongala Michel Lubaki Zhiying Chen Weidong Han | 2017 | Protein & Cell2017，8，12： | 11 |
| 8 | Studies on the evolution process of rockbursts in deep tunnels显示文摘This paper focuses on the evolution processes of different types of rockbursts occurring in deep tunnels. A series of laboratory tests and in-situ monitoring in deep tunnels excavated by tunnel boring machine (TBM) and drill-and-blast (D&B) method have been conducted to understand the mechanisms and processes of the evolution of different types of rockbursts, including strain rockburst, strain-structure slip rockburst, immediate rockburst and time-delayed rockburst. Three different risk assessment methods are proposed to evaluate the intensity and potential failure depth of rockbursts. These methods can be applied before excavation and the results can be updated according to the real-time information during excavation. Two micro-seismicity based real-time warning systems have been established for predicting various intensities of rockbursts, such as slight, moderate, intensive and extremely intensive rockbursts. Meanwhile, the probability and intensity of the rockburst are also given. The strategy for excavation and support design has been suggested for various intensities of rockbursts before excavation. The strategy for dynamic control of the rockburst evolution process is also proposed according to the monitoring results. The methodology has been successfully applied to rockburst risk reduction for deep tunnels at Jinping II hydropower project. The results have illustrated the applicability of the proposed methodology and techniques concerning rockbursts. | Xiating Feng Bingrui Chen Shaojun Li Chuanqing Zhang Yaxun Xiao Guangliang Feng Hui Zhou Shili Qiu Zhouneng Zhao Yang Yu Dongfang Chen Huajun Ming | 2012 | Journal of Rock Mechanics and Geotechnical Engineering2012，4，4： | 11 |
| 9 | The lightning activities in super typhoons over the Northwest Pacific显示文摘The spatial and temporal characteristics of lightning activities have been studied in seven super typhoons from 2005 to 2008 over the Northwest Pacific, using data from the World Wide Lightning Location Network (WWLLN). The results indicated that there were three distinct lightning flash regions in mature typhoon, a significant maximum in the eyewall regions (20-80 km from the center), a minimum from 80-200 km, and a strong maximum in the outer rainbands (out of 200 km from the center). The lightning flashes in the outer rainbands were much more than those in the inner rainbands, and less than 1% of flashes occurred within 100 km of the center. Each typhoon produced eyewall lightning outbreak during the periods of its intensification, usually several hours prior to its maximum intensity, indicating that lightning activity might be used as a proxy of intensification of super typhoon. Little lightning occurred near the center after landing of the typhoon. | PAN LunXiang QIE XiuShu LIU DongXia WANG DongFang YANG Jing | 2010 | Science China Earth Sciences2010，53，8： | 7 |
| 10 | Preparation and hydrogen gas sensitive characteristics of highly ordered titania nanotube arrays显示文摘In this paper, we report the growth and characteristics of titania nanotube arrays prepared by anodic oxidation and then annealed in an oxygen atmosphere at 500℃. The titania nanotube arrays presented high sensitivity to hydrogen gas. The crystalline phase of the samples was checked by X-ray diffraction (XRD). The differences in the nanotubes morphology attributed to the etched samples due to anodiza- tion potential, reaction time and the electrolyte concentration were analyzed by scanning electron mi- croscopy (SEM). The gas sensitive parameters of the samples were obtained from resistance, the re- sponse time and the recovery time at different temperatures. | JI HuiMing LU HuiXiang MA DongFang YU JianJun MA ShiCai | 2008 | Chinese Science Bulletin2008，53，9： | 7 |
| 11 | Experimental and numerical study on fretting wear and fatigue of full-scale railway axles显示文摘This study investigated the fretting wear and fatigue of full-scale railway axles.Fatigue tests were conducted on full-scale railway axles,and the fretting wear and fretting fatigue in the fretted zone of the railway axles were analysed.Three-dimensional finite element models were established based on the experimental results.Then,multi-axial fatigue parameters and a linear elastic fracture mechanics-based approach were used to investigate the fretting fatigue crack initiation and propagation,respectively,in which the role of the fretting wear was taken into account.The experimental and simulated results showed that the fretted zone could be divided into zones I-III according to the surface damage morphologies.Fretting wear alleviated the stress concentration near the wheel seat edge and resulted in a new stress concentration near the worn/unworn boundary in zone II,which greatly promoted the fretting crack initiation at the inner side of the fretted zone.Meanwhile,the stress concentration also increased the equivalent stress intensity factor range DKeq below the mating surface,and thus promoted the propagation of fretting fatigue crack.Based on these findings,the effect of the stress redistribution resulting from fretting wear is suggested to be taken into account when evaluating the fretting fatigue in railway axles. | Lang Zou Dongfang Zeng Yabo Li Kai Yang Liantao Lu Caiqin Yuan | 2020 | Railway Engineering Science2020，28，4： | 7 |
| 12 | Reversible hydrogels with tunable mechanical properties for optically controlling cell migration显示文摘 | Xin Wu Wenmao Huang Wen-Hao Wu Bin Xue Dongfang Xiang Ying Li Meng Qin Fei Sun Wei Wang Wen-Bin Zhang Yi Cao | 2018 | Nano Research2018，11，10： | 6 |
| 13 | A novel none once per revolution blade tip timing based blade vibration parameters identification method显示文摘The vibration caused blade High Cycle Fatigue(HCF)is seriously affects the safety operation of turbomachinery especially for aero-engine.Thus,it is crucial important to identify the blade vibration parameters and then evaluate the dynamic stress amplitude.Blade Tip Timing(BTT)method is one of the promising method to solve these problems.While,it need a high resolution Once Per Revolution(OPR)signal which is difficult to get for the aero-engine.Here,a Coupled Vibration Analysis(CVA)method for identifying blade vibration parameters by a none OPR BTT is proposed.The method assumes that every real blade has its own vibration performance at a given speed.Whereby,it can take any blade as the reference blade,and the other blades using the reference blade as the OPR for vibration displacement calculating and further parameter identifying.The proposed method is validated by numerical model.Also,experimental studies are carried out on a straight blade and a twisted three dimensional blade test rig as well as a large industrial axial compressor respectively.The results show that the proposed method can accurately identify the blade synchronous vibration parameters and quantitatively evaluate the mistuning in bladed disks,which lays a foundation for the reliability improvement of aero-engine. | Weimin WANG Xulong ZHANG Dongfang HU Dengpeng ZHANG Paul ALLAIRE | 2020 | Chinese Journal of Aeronautics2020，33，7： | 6 |
| 14 | Pathological changes in the lungs and lymphatic organs of 12 COVID-19 autopsy cases显示文摘Systematic autopsy and comprehensive pathological analyses of COVID-19 decedents should provide insights into the disease characteristics and facilitate the development of novel therapeutics.In this study,we report the autopsy findings from the lungs and lymphatic organs of 12 COVID-19 decedents—findings that evaluated histopathological changes;immune cell signature and inflammatory factor expression in the lungs,spleen and lymph nodes.Here we show that the major pulmonary alterations included diffuse alveolar damage,interstitial fibrosis and exudative inflammation featured with extensive serous and fibrin exudates,macrophage infiltration and abundant production of inflammatory factors(IL-6,IP-10,TNFo?and IL-I f).The spleen and hilar lymph nodes contained lesions with tissue structure disruption and immune cell dysregulation,including lymphopenia and macrophage accumulation.These findings provide pathological evidence that links injuries of the lungs and lymphatic organs with the fatal systematic respiratory and immune malfunction in critically ill COVID-19 patients. | Qian Liu Yu Shi Jun Cai Yaqi Duan Rongshuai Wang Hongyan Zhang Qiurong Ruan Jiansha Li Lei Zhao Yifang Ping Rong Chen Liang Ren Xiaochun Fei Heng Zhang Rui Tang Xi Wang Tao Luo Xindong Liu Xuequan Huang Zhenhua Liu Qilin Ao Yong Ren Jing Xiong Zhicheng He Haibo Wu Wenjuan Fu Pengnan Zhao Xinwei Chen Guoqiang Qu Yunyun Wang Xi Wang Jia Liu Dongfang Xiang Sanpeng Xu Xiaowei Zhou Qingrui Li Jinghong Ma Heng Li Jie Zhang Sizhe Huang Xiaohong Yao Yiwu Zhou Chaofu Wang Dingyu Zhang Guoping Wang Liang Liu Xiu-Wu Bian | 2020 | National Science Review2020，7，12： | 6 |
| 15 | Dynamic full-color digital holographic 3D display on single DMD显示文摘Digital holography has high potentials for future 3D imaging and display technology.We present a method for a dynamic full-color digital holographic 3D display on single digital micro-mirror device(DMD)with full-color,high-speed and high-fidelity characteristics.We combine the square regions of adjacent micro-mirrors into super-pixels that can modulate amplitude and phase independently.Gray images are achieved by amplitude modulation and precise positioning of each color is achieved by phase modulation.The proposed method realizes a full-color imaging based on the three primary colors and achieves measured structural similarity of more than 88%and color similarity of more than 98%,while retaining the high switch speed of 9 kHz,thus achieving dynamic full-color 3D display on charge-coupled device(CCD). | Chonglei Zhang Dongfang Zhang Zhouping Bian | 2021 | Opto-Electronic Advances2021，4，3： | 6 |
| 16 | Shiga toxin-producing Escherichia coli O104:H4: An emerging 0important pathogen in food safety显示文摘In 2011, Shiga toxin-producing Escherichia coli O104 : H4 resulted in a large outbreak of bloody diarrhea and hemolytic uremic syndrome (HUS) in Germany and 15 other countries in Europe and North America. This event raised a serious public health crisis and caused more than two billion US dollars in economic losses. In this review, we describe the classification of E. coli, the Germany outbreak, and the characteristics and epidemical source-tracing of the causative agent. We also discuss the genomics analysis of the outbreak organism and propose an open-source genomics analysis as a new strategy in combating the emerging infectious diseases. | CUI YuJun LI DongFang YANG RuiFu | 2013 | Chinese Science Bulletin2013，58，14： | 5 |
| 17 | Application of an analytic hierarchy process to hydrocarbon accumulation coefficient estimation显示文摘The hydrocarbon accumulation coefficient is a key parameter in resources evaluation by genetic techniques. Methods of obtaining its value scientifically have always been an important factor influencing evaluation credibility. In this paper, the hydrocarbon accumulation system is evaluated quantitatively by establishing a hierarchy structure model based on an analytical hierarchy process. The hydrocarbon accumulation system of a higher exploration degree is selected as a calibration area and its hydrocarbon accumulation coefficient can be calculated using methods of hydrocarbon generation potential and reservoir-scale sequence. The hydrocarbon accumulation coefficient of a petroleum accumulation system can be gained by analogy of reservoir forming comprehensive evaluation results with the calibration area. The hydrocarbon accumulation coefficient of each petroleum accumulation system in the upper reservoir-forming combination of the Liaohe Western Sag can be obtained with this method. Practice shows that using the analytical hierarchy process to quantitatively evaluate the hydrocarbon accumulation system and then quantitatively predict the hydrocarbon accumulation coefficient decreases the influence of human factors in resources evaluation, and makes the resources assessment more objective and closer to the actual geological condition. | Gao Yongjin Liu Lifeng Liu Huimin Zheng Feifei Wu Li Zhou Jingjing Qu Dongfang | 2010 | Petroleum Science2010，7，3： | 5 |
| 18 | Multiple sulfur and oxygen isotope compositions in Beijing aerosol显示文摘Multiple sulfur isotopes(32S, 33 S, 34 S, 36S) and oxygen isotopes(16O, 18O) in Beijing aerosols were measured with MAT-253 isotope mass spectrometer. The δ34S values of Beijing aerosol samples range from 1.68‰ to 12.57‰ with an average value of 5.86‰, indicating that the major sulfur source is from direct emission during coal combustion. The δ18O values vary from 5.29‰ to 9.02‰ with an average value of 5.17‰, revealing that the sulfate in Beijing aerosols is mainly composed of the secondary sulfate. The main heterogeneous oxidation of SO2 in atmosphere is related to H2O2 in July and August, whereas H2O2 oxidation and Fe3+ catalytic oxidation with SO2 exist simultaneously in September and October. Remarkable sulfur isotope mass-independent fractionation effect is found in Beijing aerosols, which is commonly attributed to the photochemical oxidation of SO2 in the stratosphere. In addition, thermochemical reactions of sulfur-bearing compounds might be also a source of sulfur isotope anomalies based on the correlation between ?33S and CAPE. | GUO ZhaoBing WU MengLong LIU FengLing WEI Ying LI DongFang | 2014 | Science China Earth Sciences2014，57，11： | 5 |
| 19 | SDS-modified Nanoporous Silver as an Efficient Electrocatalyst for Selectively Converting CO2 to CO in Aqueous Solution显示文摘Selectively electrochemical conversion of CO2 into organic fuel using renewable electricity is one of the most sought-after processes.In this paper,we report the electrochemical reduction of CO2(CO2RR)on the nanoporous Ag electrodes made of compacted Ag nanoparticles(AgNPs),which were prepared by one-step reduction in the water phase with or without the surfactant sodium dodecyl sulfate(SDS).The scanning electron microscope(SEM)characterizations show that the compacted Ag electrodes have the nanoporous morphology formed by stacking AgNPs.Compared with the nanoporous Ag electrode without SDS modification(C-AgNPs),the SDS-modified AgNPs electrode(C-AgNPs-SDS)is highly effective in improving selective CO production in a wide range of potentials(-0.69 V--1.19 V,vs.RHE),with a Faradaic efficiency of 92.2% and a current density of -8.23 mA·cm^-2 for CO production at -0.79 V(vs.RHE).C-AgNPs-SDS is also catalytically stable with only less than 7% deactivation after 8 h of continuous electrolysis. | Lei Shi Yuning Zhang Xiaofei Han Dongfang Niu Jinlong Sun Jenny Y.Yang Shuozhen Hu Xinsheng Zhang | 2019 | Chinese Journal of Chemistry2019，37，4： | 5 |
| 20 | Global sources, emissions, transport and deposition of dust and sand and their effects on the climate and environment: a review显示文摘 | Feng Wang Xueqiu Zhao Cynthia Gerlein-Safdi Yue Mu Dongfang Wang Qi Lu | 2017 | Frontiers of Environmental Science & Engineering2017，11，1： | 5 |
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