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| 1 | Surveillance of Mycoplasma pneumoniae infection among children in Beijing from 2007 to 2012显示文摘 | Zhao Hanqing Li Shaoli Cao Ling Yuan Yi Xue Guanhua Feng Yanling Yan Chao Wang Liqiong Fan Zhaoyang Sun Hongmei | 2014 | Chinese Medical Journal2014,,7: | 61 |
| 2 | Wnt and BMP signaling crosstalk in regulating dental stem cells:Implications in dental tissue engineering显示文摘Tooth is a complex hard tissue organ and consists of multiple cell types that are regulated by important signaling pathways such as Wnt and BMP signaling.Serious injuries and/or loss of tooth or periodontal tissues may significantly impact aesthetic appearance,essential oral functions and the quality of life.Regenerative dentistry holds great promise in treating oral/dental disorders.The past decade has witnessed a rapid expansion of our understanding of the biological features of dental stem cells,along with the signaling mechanisms governing stem cell self-renewal and differentiation.In this review,we first summarize the biological characteristics of seven types of dental stem cells,including dental pulp stem cells,stem cells from apical papilla,stem cells from human exfoliated deciduous teeth,dental follicle precursor cells,periodontal ligament stem cells,alveolar bone-derived mesenchymal stem cells(MSCs),and MSCs from gingiva.We then focus on how these stem cells are regulated by bone morphogenetic protein(BMP)and/or Wnt signaling by examining the interplays between these pathways.Lastly,we analyze the current status of dental tissue engineering strategies that utilize oral/dental stem cells by harnessing the interplays between BMP and Wnt pathways.We also highlight the challenges that must be addressed before the dental stem cells may reach any clinical applications.Thus,we can expect to witness significant progresses to be made in regenerative dentistry in the coming decade. | Fugui Zhang Jinlin Song Hongmei Zhang Enyi Huang Dongzhe Song Viktor Tollemar Jing Wang Jinhua Wang Maryam Mohammed Qiang Wei Jiaming Fan Junyi Liao Yulong Zou Feng Liu Xue Hu Xiangyang Qu Liqun Chen Xinyi Yu Hue H.Luu Michael J.Lee Tong-Chuan He Ping Ji | 2016 | Genes & Diseases2016,3,4: | 16 |
| 3 | Single-cell RNA-seq reveals the diversity of trophoblast subtypes and patterns of differentiation in the human placenta显示文摘胎盘为成功的怀孕和胎儿和怀孕女人的健康是关键的。然而,人的 trophoblast 系怎么被调整,包括胎盘的房间的分类,子类型糟糕被理解。这里,我们在排序的胎盘的房间上执行了定序的单个房间的 RNA (RNA-seq ) 从第一三个月并且秒三个月人胎盘。已知的 cytotrophoblast 房间(CTB ) 的房间的新子类型, extravillous trophoblast 房间(EVT ) , Hofbauer 房间,和间充质的 stromal 房间被识别, cell-type-specific 基因签名被定义。机能上地,这研究揭示了人的胎盘的许多以前未知的功能。尤其是, 102 多肽荷尔蒙基因被发现被胎盘的房间的各种各样的子类型表示,它在调整母亲的生理学的胎儿的生长和改编到怀孕建议建筑群和这些荷尔蒙的重要角色。这些结果在单个房间的分辨率记录人的胎盘的 trophoblast 区别并且因此在怀孕的早阶段期间推进我们人的胎座式的理解。 | Yawei Liu Xiaoying Fan Rui Wang Xiaoyin Lu Yan-Li Dang Huiying Wang Hai-Yan Lin Cheng Zhu Hao Ge James C. Cross Hongmei Wang | 2018 | Cell Research2018,28,8: | 15 |
| 4 | Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event. | TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou | 2018 | Science China(Physics,Mechanics & Astronomy)2018,61,3: | 12 |
| 5 | MiR-98 promotes chondrocyte apoptosis by decreasing Bcl-2 expression in a rat model of osteoarthritis显示文摘 | Jing Wang Lingqiang Chen Song Jin Jun Lin Hongmei Zheng Hong Zhang Hongtao Fan Fang He Sha Ma Qin Li | 2016 | Acta Biochimica et Biophysica Sinica2016,48,10: | 8 |
| 6 | Effect of SiO2 addition on NH4HSO4 decomposition and SO2 poisoning over V2O5-MoO3/TiO2-CeO2 catalyst显示文摘The deposition of NH4 HSO4 and the poisoning effect of SO2 on SCR catalyst are the main obstacles that restrict the industrial application of CeO2-doped SCR catalysts.In this work,deposited NH4 HSO4 decomposition behavior and SO2 poisoning over V2 O5-MoO3/TiO2 catalysts modified with CeO2 and SiO2 were investigated.By the means of characterization analysis,it was found that the addition of SiO2 into VMo/Ti-Ce had an impact on the interaction existed between catalyst surface atoms and NH4 HSO4.Temperatureprogrammed methods and in situ diffused reflectance infrared Fourier transform spectroscopy(DRIFTS)experiments indicated that the doping of SiO2 promoted the decomposition of deposited NH4 HSO4 on VMo/Ti-Ce catalyst surface by reducing the thermal stability of NH4 HSO4 and enhancing the NH4 HSO4 reactivity with NO in low temperature.And this improvement may be the reason for the better catalytic activity than VMo/Ti-Ce in the case of NH4 HSO4 deposition.Accompanied with cerium sulfate species generated over catalyst surface,the conversion of SO2 to SO3 was inhibited in SiCe mixed catalyst.The addition of SiO2 could promote the decomposition of cerium sulfate,which may be a potential strategy to enhance the resistance of SO2 poisoning over CeO2-modifed catalysts. | Chengqiang Zheng Teng Cheng Linjun Yang Hao Wu Hongmei Fan | 2020 | Journal of Environmental Sciences2020,32,5: | 6 |
| 7 | SO_2/Hg removal from flue gas by dry FGD显示文摘To study the mechanism of SO 2 and Hg removal from flue gas, an experimental packed bed reactor was designed to simulate the dry FGD, where a mixture of lime and fly ash in ratio 1:3 w/w was used as the SO 2 and Hg sorbent, and steam at temperature of 100℃ was applied for activation of the sorbent, while the activation time set to 20 min. The experimental factors including the SO 2 /Hg sorbent characteristics, 50% breakthrough time for SO 2 /Hg removal, sorbent packed bed depth and reaction temperature were investigated. The experimental results show that after steam activation, the BET specific surface area and specific pore volume increased from 37.8 to 45.5 m 2 /g and from 0.42 to 0.51 cm 3 /g, respectively. With activation of the sorbent by steam, the 50% breakthrough times of SO 2 and Hg removal increased from 34 to 42 min and from 23 to 45 min, respectively. When the packed bed depth was increased from 5 to 25 mm, the 50% breakthrough times for Hg and SO 2 removal increased from 12 to 52 min and from 6 to 47 min, respectively. With the increase of the reaction temperature, the 50% breakthrough of SO 2/Hg removal decreased accordingly. Steam activation can efficiently improve SO 2 /Hg removal simultaneously. | Wang Fan Wang Hongmei Zhang Fan Zhu Jinwei Tian Gang Liu Yu Mao Jixian | 2012 | International Journal of Mining Science and Technology2012,22,1: | 5 |
| 8 | Catalytic reduction of NO_x by biomass-derived activated carbon supported metals显示文摘In this study,to prepare a series of activated carbon-supported metals for the catalytic reduction of NO_x to N_2 in excess O_2,activated carbons derived from lignocellulosic and herbaceous biomasses were selected as the reducing agents,and alkali and transition metals were used as the catalytic active phases.The effects of the type of biomass,carbonization temperature and catalyst composition on NO_x reduction efficiency were analyzed in a fixed-bed flow reactor.The results showed that two temperature regimes are present for the NO_x-carbon reaction:at temperatures below 250°C,the NO_x adsorption process on the carbon surface was predominant,whereas true NO_x reduction by carbon occurred at temperatures above 250°C,producing N_2,CO_2 and CO.The influence of the carbonization temperature on carbon reactivity depended on the effect of the carbonization temperature on the carbon surface area and the reduction of the metal species on carbon.All studied metals catalyzed both NO_xand O_2reduction by carbon,and potassium could strongly enhance the C-NO_x reaction without substantial carbon consumption by O_2.Moreover,the potassium supported by sawdust-derived activated carbon exhibited higher selectivity and capacity towards NO_x reduction than did its previously reported coal-derived counterparts.These properties were ascribed to the high dispersion of the active potassium species on the carbon surface,as observed through the comparison of X-ray photoelectron spectroscopy and powder X-ray diffraction results for the carbons made from biomass and coal-based precursors. | Yun Shu Fan Zhang Fan Wang Hongmei Wang | 2018 | Chinese Journal of Chemical Engineering2018,26,10: | 5 |
| 9 | Risk Factors for Age-Related Macular Degeneration in Elderly Chinese Population in Shenyang of China显示文摘Objective The paper aims to evaluate the risk factors for age‐related macular degeneration (AMD) in elderly Chinese population in Shenyang,a northeast city of China.Methods A case‐control study was conducted to investigate the risk factors for the prevalence of AMD.Ninety three AMD patients diagnosed by a complete ophthalmic examination were recruited as cases from the outpatient departments of two eye hospitals in Shenyang,while 108 normal subjects of similar age and sex were recruited as controls.A questionnaire was administered among both cases and controls.Results AMD patients aged 60 years and older accounted for 75.3%.There were significantly higher educational levels,shorter smoking history,less sunlight exposure and cataract,and higher proportion of antioxidants intake in controls than in AMD patients.The frequency of intake of fruits,legumes,fish and shrimps was significantly higher in controls than in AMD patients.In a binary logistic regression analysis,smoking and cataract were the risk factors for AMD (OR:4.44,95% CI:2.27‐8.69;OR:4.47,95% CI:2.26‐8.85 respectively).The high educational background was a protective factor for AMD (OR:0.761,95% CI:0.51‐0.98).Conclusion A low educational background,smoking and cataract are associated with a higher prevalence of AMD. | JIA LiHong SHEN XueLi FAN Rui SUN Yan PAN XingYue YANH HongMei LIU Lu | 2011 | Biomedical and Environmental Sciences2011,24,5: | 4 |
| 10 | A male-ABCD algorithm for hepatocellular carcinoma risk prediction in HBs Ag carriers显示文摘Objective: Hepatocellular carcinoma(HCC) development among hepatitis B surface antigen(HBs Ag) carriers shows gender disparity, influenced by underlying liver diseases that display variations in laboratory tests. We aimed to construct a risk-stratified HCC prediction model for HBs Ag-positive male adults.Methods: HBs Ag-positive males of 35-69 years old(N=6,153) were included from a multi-center populationbased liver cancer screening study. Randomly, three centers were set as training, the other three centers as validation. Within 2 years since initiation, we administrated at least two rounds of HCC screening using Bultrasonography and α-fetoprotein(AFP). We used logistic regression models to determine potential risk factors,built and examined the operating characteristics of a point-based algorithm for HCC risk prediction.Results: With 2 years of follow-up, 302 HCC cases were diagnosed. A male-ABCD algorithm was constructed including participant's age, blood levels of GGT(γ-glutamyl-transpeptidase), counts of platelets, white cells,concentration of DCP(des-γ-carboxy-prothrombin) and AFP, with scores ranging from 0 to 18.3. The area under receiver operating characteristic was 0.91(0.90-0.93), larger than existing models. At 1.5 points of risk score,26.10% of the participants in training cohort and 14.94% in validation cohort were recognized at low risk, with sensitivity of identifying HCC remained 100%. At 2.5 points, 46.51% of the participants in training cohort and 33.68% in validation cohort were recognized at low risk with 99.06% and 97.78% of sensitivity, respectively. At 4.5 points, only 20.86% of participants in training cohort and 23.73% in validation cohort were recognized at high risk,with positive prediction value of 22.85% and 12.35%, respectively.Conclusions: Male-ABCD algorithm identified individual's risk for HCC occurrence within short term for their HCC precision surveillance. | Yuting Wang Minjie Wang He Li Kun Chen Hongmei Zeng Xinyu Bi Zheng Zhu Yuchen Jiao Yong Wang Jian Zhu Hui Zhao Xiang Liu Chunyun Dai Chunsun Fan Can Zhao Deyin Guo Hong Zhao Jianguo Zhou Dongmei Wang Zhiyuan Wu Xinming Zhao Wei Cui Xuehong Zhang Jianqiang Cai Wanqing Chen Chunfeng Qu | 2021 | Chinese Journal of Cancer Research2021,33,3: | 3 |
| 11 | Micronuclei rate and hypoxanthine phosphoribosyl transferase mutation in radon-exposed rats显示文摘在有氡暴露的老鼠的基因变化被微原子核技术和低亚硫酸钠黄质 phosphoribosyl transferase (hprt ) 的察觉学习变化。在外部血淋巴细胞的微原子核和在吸入氡的老鼠的气管支气管的上皮的房间的率比控制的高(P <
0.05 ) 。类似的结果从 hprt 试金被获得,它在暴露氡的老鼠显示出更高的变化频率。我们的结果建议那微原子核率和 hprt 缺乏能与氡暴露为基因变化被用作简历标记。 | Fengmei Cui Saijun Fan Mingjiang Hu Jihua Nie Hongmei Li Jian Tong | 2008 | Progress in Natural Science:Materials International2008,18,10: | 3 |
| 12 | Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite显示文摘As China’s first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2017, is a wide-band(1-250 ke V) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2-3 Me V. It was designed to perform pointing, scanning and gamma-ray burst(GRB)observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be reconstructed.Here we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results. | Shuang-Nan Zhang TiPei Li FangJun Lu LiMing Song YuPeng X u CongZhan Liu Yong Chen XueLei Cao QingCui Bu Zhi Chang Gang Chen Li Chen TianXiang Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong Yuan Yuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan Can Gungor ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge Ou JinLu Qu Na Sai RenCheng Shang GuoHong Shen Liang Sun Ying Tan Lian Tao YouLi Tuo Chen Wang ChunQin Wang GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BaiYang Wu BoBing Wu Mei Wu GuangCheng Xiao ShaoLin Xiong LinLi Yan JiaWei Yang Sheng Yang YanJi Yang QiBin Yi Bin Yuan AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang ShenYi Zhangs Shu Zhang Tong Zhang WanChang Zhang Wei Zhang WenZhao Zhang Yi Zhang YiFei Zhang YongJie Zhang Yue Zhang Zhao Zhang Zhi Zhang ZiLiang Zhang HaiSheng Zhao XiaoFan Zhao ShiJie Zheng JianFeng Zhou YuXuan Zhu Yue Zhu RenLin Zhuang | 2020 | Science China(Physics,Mechanics & Astronomy)2020,63,4: | 2 |
| 13 | Effect of hindlimb unloading on resting intracellular calcium in intrafusal fibers and ramp-and-hold stretches evoked responsiveness of soleus muscle spindles in conscious rats显示文摘 | Yongjin Zhu Xiaoli Fan Xiaohui Li Sudi Wu Hongmei Zhang Lei Yu | 2008 | Neuroscience Letters2008,,3: | 1 |
| 14 | Reactive plasma spraying synthesis and characterization of TiB 2 –TiC–Al 2 O 3 /Al composite coatings on a magnesium alloy显示文摘 | Jiaying Xu Binglin Zou Xizhi Fan Sumei Zhao Yu Hui Ying Wang Xin Zhou Xiaolong Cai Shunyan Tao Hongmei Ma Xueqiang Cao | 2014 | Journal of Alloys and Compounds2014,,: | 1 |
| 15 | Prevention and Control of Iodine Deficiency Disorders—China,1995–2020显示文摘Basic Information about Iodine Deficiency Disorders Iodine is an essential micronutrient for the human body and an important raw material for the synthesis of thyroid hormones.Thyroid hormones maintain the basic activities of the body and have different effects on almost all systems of the body by promoting growth and development,participating in brain development,regulating metabolism,and impacting most organs and system functions. | Peng Liu Lijun Fan Fangang Meng Xiaohui Su Shoujun Liu Hongmei Shen Dianjun Sun | 2020 | China CDC weekly2020,2,20: | 1 |
| 16 | Self-propagating high-temperature synthesis of TiC–TiB 2 -based Co cermets from a Co–Ti–B 4 C system and fabrication of coatings using the cermet powders显示文摘 | Binglin Zou Jiaying Xu Ying Wang Sumei Zhao Xizhi Fan Yu Hui Xin Zhou Wenzhi Huang Xiaolong Cai Shunyan Tao Hongmei Ma Xueqiang Cao | 2013 | Chemical Engineering Journal2013,,: | 1 |
| 17 | Synthesis and characterization of in situ TiC–TiB 2 composite coatings by reactive plasma spraying on a magnesium alloy显示文摘 | Binglin Zou Shunyan Tao Wenzhi Huang Zuhair S. Khan Xizhi Fan Lijian Gu Ying Wang Jiaying Xu Xiaolong Cai Hongmei Ma Xueqiang Cao | 2013 | Applied Surface Science2013,,: | 1 |
| 18 | Identification of the RNA chaperone activity of recombinant human tumor necrosis factor alpha in vitro显示文摘 | Guojun Cao Guang Yang Zhaohui Liu Xuemei Liu Jie Zhang Dajin Zhang Nongle Liu Hongmei Ding Ming Fan Beifen Shen Ningsheng Shao | 2005 | Biochemical and Biophysical Research Communications2005,,2: | 1 |
| 19 | Altering membrane structure to enhance water permeability and performance of anion exchange membrane fuel cell显示文摘Water management has been proven significant for enhancing both performance and durability of anion exchange membrane fuel cell. Besides searching new material, decreasing membrane thickness and modifying operation parameters, a simple and universal method of altering membrane structure is proposed in this work. Composite membranes made by unique processing method that includes both casting and electrospinning processes were compared with traditional casting membrane, all with the same thickness of 40 μm. Comparing to traditional casting membrane, the composite membrane put at proper position shows a higher water permeability, thus even more than 50% enhancement of the peak performance. | YANG Yue GAO XueQiang SONG Wei YU HongMei LI WenBin QI ManMan HUANG He WANG PengHao FAN ZhiXuan SHAO ZhiGang | 2021 | Science China(Technological Sciences)2021,64,2: | 1 |
| 20 | Montmorillonite–Cu(II)/Fe(III) oxides magnetic material for removal of cyanobacterial Microcystis aeruginosa and its regeneration显示文摘 | Zhengwen Gao Xianjia Peng Hongmei Zhang Zhaokun Luan Bin Fan | 2009 | Desalination2009,,1: | 1 |