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| 1 | Qinghu zircon:A working reference for microbeam analysis of U-Pb age and Hf and O isotopes显示文摘Zircon is the most useful mineral for studies in U-Pb geochronology and Hf and O isotope geochemistry.Matrix effect is a major problem of the microbeam techniques such as SIMS and LA-(MC)-ICPMS.Therefore,external standardization using well-characterized natural zircon standards is fundamental for accurate microbeam measurements.While the isotopic geochronology and geochemistry laboratories equipped with microbeam analytical facilities have been increasingly established in China during the past decade,applications of the isotopic microanalysis are still limited due to shortage of available standards.We report here the Qinghu zircon as a potential new working reference for microbeam analysis of zircon U-Pb age and O-Hf isotopes.This zircon was separated from the Qinghu quartz monzonite from the western Nanling Range,Southeast China.It is fairly homogeneous in U-Pb age and Hf and O isotopes in terms of large amounts of mircobeam measurements by LA-MC-ICPMS and SIMS at the scales of 20–60 m.SIMS measurements yield consistent206Pb/238U age within analytical uncertainties with that obtained by ID-TIMS.Precise determinations of O isotopes by IRMS and Hf isotopes by solution MC-ICPMS are in good agreement with the statistical mean of microbeam measurements.We recommend U-Pb age of=159.5±0.2 Ma(2SE),18O=5.4‰±0.2‰(2SD)and176Hf/177Hf=0.283002±0.000004(2SD)as the best reference values for the Qinghu zircon. | LI XianHua TANG GuoQiang GONG Bing YANG YueHeng HOU KeJun HU ZhaoChu LI QiuLi LIU Yu LI WuXian | 2013 | Chinese Science Bulletin2013，58，36： | 60 |
| 2 | Transmission Dynamics of an Outbreak of the COVID-19 Delta Variant B.1.617.2——Guangdong Province,China,May-June 2021显示文摘On May 21,2021,a local case of coronavirus disease 2019(COVID-19)was confirmed in a 75-year-old woman(experienced onset of symptoms on May 18)in Liwan District,Guangzhou City,Guangdong Province,China.The number of infections has increased in the following 10 days and led to 5 generations of transmission. | Meng Zhang Jianpeng Xiao Aiping Deng Yingtao Zhang Yali Zhuang Ting Hu Jiansen Li Hongwei Tu Bosheng Li Yan Zhou Jun Yuan Lei Luo Zimian Liang Youzhi Huang Guoqiang Ye Mingwei Cai Gongli Li Bo Yang Bin Xu Ximing Huang Yazun Cui Dongsheng Ren Yanping Zhang Min Kang Yan Li | 2021 | China CDC weekly2021，3，27： | 51 |
| 3 | Effect of cypermethrin insecticide on the microbial community in cucumber phyllosphere显示文摘Cucumber (Cucumis sativus) is one of the most widely used vegetable in the world,and different pesticides have been extensively used for controlling the insects and disease pathogens of this plant.However,little is known about how the pesticides affect the microbial community in cucumber phyllosphere.This study was the first attempt to assess the impact of pyrethroid insecticide cyperemethrin on the microbial communities of cucumber phyllosphere using biochemical and genetic approaches.Phospholipid fatty acid (PLFA) assay indicated that cyperemethrin insecticide treatment led to a significant increase in both total and bacterial biomass and a decrease in fungal biomass and the ratio of Gram-positive (GP) bacteria to Gram-negative (GN) bacteria within the cucumber phyllosphere.Principal-component analyses (PCA) suggested that the number of unsaturated and cyclopropane PLFAs (16:1ω9t,18:1ω7,cy17:0,cy19:0) increased with the insecticide treatment,whereas the saturated PLFA i16:0,i17:0 decreased.The increase of GN bacteria implied that the cypermethrin insecticide might be a nutrient for the growth of these phyllosphere microbes.Terminal restriction fragment length polymorphism (T-RFLP) reinforced the PLFA results.A significant change of bacterial community structure was observed in the separate dendrogram cluster between control and treated samples with the cucumber phyllosphere following cypermethrin insecticide treatment.Moreover,the increased terminal restriction fragments (T-RFs) (58,62,89,99,119,195,239,311,340,and 473 bp) indicated that some bacteria might play a significant role in the insecticide degradation within the cucumber phylosphere,whereas the disappeared T-RFs (44,51,96,223,306,and 338 bp) implied that some other bacteria might potentially serve as microbial indicator of cyperemethrin insecticide exposure. | Baoguo ZHANG Zhihui BAI | 2008 | Journal of Environmental Sciences2008，20，11： | 19 |
| 4 | Hierarchical graphene foam-based phase change materials with enhanced thermal conductivity and shape stability for efficient solar-to-thermal energy conversion and storage显示文摘最近, graphene 泡沫(GF ) 与一三维(3D ) 互连指导模板的化学蒸汽免职(CVD ) 生产的网络被用来与提高的热电导率准备合成阶段变化材料(脉冲编码调制) 。然而, GF 的毛孔尺寸象几百测微计一样大,导致为从在到 GF 神气墙的大毛孔内的 PCM 的热转移的一个显著热电阻。在这研究,新奇 3D 层次 GF (HGF ) 被用空 graphene 网络填满 GF 的毛孔获得。HGF 然后被用来准备基于的石蜡蜡(PW ) 合成脉冲编码调制。PW/HGF 合成脉冲编码调制的热传导性分别地比 PW/GF 合成脉冲编码调制和纯 PW 的高是 87% 和 744% 。PW/HGF 合成脉冲编码调制也与在 100 次骑车比 PW/GF 合成脉冲编码调制,在阶段变化温度的可以忽略的变化,是 95% 纯 PW 的高热的精力存储密度,好热可靠性,和化学稳定性展出更好的形状稳定性。更重要地, PW/HGF 合成脉冲编码调制与高 light-to-thermal 精力变换和存储效率允许光驱动的热精力存储,显示它为在太阳能的利用和存储的应用的大潜力。 | Guoqiang Qi Jie Yang Ruiying Bao Dongyun Xia Min Cao Wei Yang Mingbo Yang Dacheng Wei | 2017 | Nano Research2017，10，3： | 18 |
| 5 | Efficacy and safety evaluation of intravenous infusion of cervus and cucumis polypeptides for treatment of avascular necrosis of the femoral head: a randomized clinical trial显示文摘OBJECTIVE: To investigate the efficacy and safety of intravenous cervus and cucumis polypeptides for treating avascular necrosis of the femoral head(ANFH) in regard to pain and hip function in a randomized clinical trial.METHODS: A total of 96 subjects with ANFH who were recruited at the Orthopaedic Hospital Affiliated with Hebei United University and Qian Hai Femoral Head Hospital of Beijing were assigned by lottery to an intervention group(n = 48) or a control group(n = 48). All subjects underwent physical therapy and rehabilitation exercises. In addition,subjects in the intervention group were given intravenous infusions of cervus and cucumis polypeptides. Visual analogue scale(VAS), Harris hip score,and radiography or magnetic resonance imaging were applied to assess all subjects at the beginning of treatment and 3, 6, and 9 months afterward. All the subjects were followed up for 2 years.RESULTS: At the beginning of treatment, there were no statistically significant differences between the two groups in terms of the general condition of patients or the VAS and Harris hip scores(all P > 0.05). At 3, 6, and 9 months after treatment,however, the VAS score decreased and the Harris hip score increased in all patients, with the improvement of intervention group significantly greater than that of the control group(P < 0.05).The total effectiveness rates for the intervention and control groups were 89.58% and 70.83%, respectively, with the difference being statistically significant(P < 0.05). There was no statistically significant difference between the two groups in terms of the safety of the injections(P > 0.05).CONCLUSION: Intravenous infusion of cervus and cucumis polypeptides relieved pain and improved hip function of subjects with ANFH.Thus, the intravenous infusion of cervus and cucumis polypeptides was a safe, effective treatment for ANFH. | Wei Liyou Zhang Hongwei Li Xinmin Yang Chunyan Wang Guoqiang Zhang Lifeng Cui Mingwu Han Lijun | 2016 | Journal of Traditional Chinese Medicine2016，36，1： | 15 |
| 6 | Wheat genomic study for genetic improvement of traits in China显示文摘Bread wheat(Triticum aestivum L.)is a major crop that feeds 40%of the world’s population.Over the past several decades,advances in genomics have led to tremendous achievements in understanding the origin and domestication of wheat,and the genetic basis of agronomically important traits,which promote the breeding of elite varieties.In this review,we focus on progress that has been made in genomic research and genetic improvement of traits such as grain yield,end-use traits,flowering regulation,nutrient use efficiency,and biotic and abiotic stress responses,and various breeding strategies that contributed mainly by Chinese scientists.Functional genomic research in wheat is entering a new era with the availability of multiple reference wheat genome assemblies and the development of cutting-edge technologies such as precise genome editing tools,highthroughput phenotyping platforms,sequencing-based cloning strategies,high-efficiency genetic transformation systems,and speed-breeding facilities.These insights will further extend our understanding of the molecular mechanisms and regulatory networks underlying agronomic traits and facilitate the breeding process,ultimately contributing to more sustainable agriculture in China and throughout the world. | Jun Xiao Bao Liu Yingyin Yao Zifeng Guo Haiyan Jia Lingrang Kong Aimin Zhang Wujun Ma Zhongfu Ni Shengbao Xu Fei Lu Yuannian Jiao Wuyun Yang Xuelei Lin Silong Sun Zefu Lu Lifeng Gao Guangyao Zhao Shuanghe Cao Qian Chen Kunpu Zhang Mengcheng Wang Meng Wang Zhaorong Hu Weilong Guo Guoqiang Li Xin Ma Junming Li Fangpu Han Xiangdong Fu Zhengqiang Ma Daowen Wang Xueyong Zhang Hong-Qing Ling Guangmin Xia Yiping Tong Zhiyong Liu Zhonghu He Jizeng Jia Kang Chong | 2022 | Science China(Life Sciences)2022，65，9： | 9 |
| 7 | Enhanced methane production in an anaerobic digestion and microbial electrolysis cell coupled system with co-cultivation of Geobacter and Methanosarcina显示文摘The anaerobic digestion(AD)and microbial electrolysis cell(MEC)coupled system has been proved to be a promising process for biomethane production.In this paper,it was found that by co-cultivating Geobacter with Methanosarcina in an AD–MEC coupled system,methane yield was further increased by 24.1%,achieving to 360.2 m L/g-COD,which was comparable to the theoretical methane yield of an anaerobic digester.With the presence of Geobacter,the maximum chemical oxygen demand(COD)removal rate(216.8 mg COD/(L·hr))and current density(304.3 A/m_3)were both increased by 1.3 and 1.8 fold compared to the previous study without Geobacter,resulting in overall energy efficiency reaching up to 74.6%.Community analysis demonstrated that Geobacter and Methanosarcina could coexist together in the biofilm,and the electrochemical activities of both were confirmed by cyclic voltammetry.Our study observed that the carbon dioxide content in total gas generated from the AD reactor with Geobacter was only half of that generated from the same reactor without Geobacter,suggesting that Methanosarcina may obtain the electron transferred from Geobacter for the reduction of carbon dioxide to methane.Taken together,Geobacter not only can improve the performance of the MEC system,but also can enhance methane production. | Qi Yin Xiaoyu Zhu Guoqiang Zhan Tao Bo Yanfei Yang Yong Tao Xiaohong He Daping Li Zhiying Yan | 2016 | Journal of Environmental Sciences2016，28，4： | 9 |
| 8 | Lipogenesis in myoblasts and its regulation of CTRP6 by AdipoR1/Erk/PPARγ signaling pathway显示文摘在 C2C12 myoblasts 的导致的 lipogenesis 和它的规定仍然保持大部分不清楚。这里,我们发现鸡尾酒 methodcould 显著地通过调整类脂化合物导致 lipogenesis 在 myoblasts 的新陈代谢的基因和 Erk1/2 phosphorylation。同时, CTRP6 的表示和分泌物在宫外的 lipogenesis 期间被增加。而且, CTRP6 击倒下面调整 lipogenic 基因的层次和在早 lipogenic 的 phosphorylated Erk1/2 (p-Erk1/2 ) 上演,而在终端区别的起来调整的 p-Erk1/2。有趣地, CTRP6 siRNA 的效果在 myoblasts 是稀释 byU0126 (一个特殊 p-Erk1/2 禁止者) 。而且, AdipoR1,不是 AdipoR2,首先在有丝分裂的同种细胞的扩大的过程期间作为受体 ofCTRP6 被识别。一起,我们建议 CTRP6 调停通过在 myoblasts 表明小径的 AdipoR1/Erk/PPAR 的宫外的 lipogenesis。我们的调查结果将流轻在小说生物在 myoblast lipogenesis 期间 CTRP6 工作并且提供由 lipogenic regulationin 改进家畜的肉质量的一个有希望的方向骨胳的肌肉 myoblasts。 | Wenjing Wu Yunmei Sun Chen Zhao Cunzhen Zhao Xiaochang Chen Guoqiang Wang Weijun Pang Gongshe Yang | 2016 | Acta Biochimica et Biophysica Sinica2016，48，6： | 9 |
| 9 | Mechanism of low thermal conductivity of xonotlite-silica aerogel nanoporous super insulation material显示文摘In an effort to incorporate the low thermal conductivity of the silica aerogel and the superior structure strength of the xonotlite,a composite material of these two was produced. It was synthesized under vacuum condition and dried by supercritical drying technique. The thermal conductivity of the new material,which is at 298K with the gas pressure ranging from 1.01×105 to 1×10-2Pa,was measured using the transient hot-strip method. The mechanism of the low thermal conductivity was studied. The re-sults indicate that the low thermal conductivity mainly results from the significant decrease of gaseous thermal conductivity of the new material due to the restriction of the motion of gas molecules in its fine structures. The formation of the fine structures is be-cause the new material takes the pore structure of the silica aerogel which consists of mainly nanometer-sized pores. | Hailong Yang Wen Ni Deping Chen Guoqiang Xu Tao Liang Li Xu | 2008 | Journal of University of Science and Technology Beijing2008，15，5： | 8 |
| 10 | Genomic insights into the fast growth of paulownias and the formation of Paulownia witches' broom显示文摘Paulownias are among the fastest growing trees in the world,but they often suffer tremendous loss of wood production due to infection by Paulownia witches'broom(PaWB)phytoplasmas.In this study,we have sequenced and assembled a high-quality nuclear genome of Paulownia fortunei,a commonly cultivated paulownia species.The assembled genome of P.fortunei is 511.6 Mb in size,with 93.2%of its sequences anchored to 20 pseudo-chromosomes,and it contains 31985 protein-coding genes.Phylogenomic analyses show that the family Paulowniaceae is sister to a clade composed of Phrymaceae and Orobanchaceae.Higher photosynthetic efficiency is achieved by integrating C3 photosynthesis and the crassulacean acid metabolism pathway,which may contribute to the extremely fast growth habit of paulownia trees.Comparative transcriptome analyses reveal modules related to cambial growth and development,photosynthesis,and defense responses.Additional genome sequencing of PaWB phytoplasma,combined with functional analyses,indicates that the effector PaWB-SAP54 interacts directly with Paulownia PfSPLa,which in turn causes the degradation of PfSPLa by the ubiquitin-mediated pathway and leads to the formation of witches'broom.Taken together,these results provide significant insights into the biology of paulownias and the regulatory mechanism for the formation of PaWB. | Yabing Cao Guiling Sun Xiaoqiao Zhai Pingluo Xu Liming Ma Minjie Deng Zhenli Zhao Haibo Yang Yanpeng Dong Zhonghai Shang Yujie Lv Lijun Yan Haifang Liu Xibing Cao Bingbing Li Zhe Wang Xiaogai Zhao Haiyan Yu Fan Wang Wen Ma Jinling Huang Guoqiang Fan | 2021 | Molecular Plant2021，14，10： | 7 |
| 11 | ESTIMATION METHOD ON THE BATTERY STATE OF CHARGE FOR HYBRID ELECTRIC VEHICLE显示文摘A combined algorithm for battery state of charge(SOC)estimation is proposed to solve the critical issue of hybrid electric vehicle(HEV).To obtain a more accurate SOC,both coulomb-accumulation and battery resistance-capacitor(RC)model are weighted combined to compensate the deficiencies of individual methods.In order to solve the key issue of coulomb-accumulation,the battery thermal model is used.Based on the principle of energy conservation,the heat generated from battery charge and discharge process is converted into the equivalent electricity to calculate charge and discharge efficiency under variable current.The extended Kalman filter(EKF)as a closed loop algorithm is applied to estimate the parameters of resistance-capacitor model.The input variables do not increase much computing difficulty.The proposed combined algorithm is implemented by adjusting the weighting factor of coulomb- accumulation and resistance-capacitor model In the end,four different methods including Ah-efficiency,Ah-Equip,RC-SOC and Combined-SOC are compared in federal testing procedure (FTP)drive cycle.The experiment results show that the proposed method has good robustness and high accuracy which is suitable for HEV application. | QIANG Jiaxi AO Guoqiang YANG Lin | 2008 | Chinese Journal of Mechanical Engineering2008，21，3： | 7 |
| 12 | Characteristics of pantograph‐catenary arc under low air pressure and strong airflow显示文摘Pantograph‐catenary arc fault is the primary factor threatening the stability of the power transmission for high‐speed railway.The motion characteristics of the pantograph‐catenary arc under low air pressure and strong airflow is significantly different from the case under atmospheric pressure.In this paper,an experimental platform of panto-graph‐catenary arc was built to investigate arc root position‐time and arc column lon-gitudinal drift height‐time characteristic curves under different air pressures and airflow velocites.Via analysing the corresponding results,it can be found that there are different arc root-arc column traction mechanisms at different stages of arc development.The arcing time and arc root stagnation time under low air pressure are significantly longer than the case under atmospheric pressure,resulting in more serious electrode ablation.The arc column longitudinal drift velocity and height are greater with the increase of airflow velocity.Two typical irregular arc motion phenomena-arc root jumping and arc reignition are observed.To clarify the internal mechanism of the above phenomenon,a magnetohydrodynamics(MHD)model of the pantograph‐catenary arc was lauched,the influence mechanism of the pantograph‐catenary arc temperature and voltage are studied,and the physical process of arc temperature oscillation is analysed.The research results provide theoretical support for arc protection in high‐altitude areas. | Zhilei Xu Guoqiang Gao Wenfu Wei Zefeng Yang Wenhan Xie Keliang Dong Yaguang Ma Yan Yang Guangning Wu | 2022 | High Voltage2022，7，2： | 7 |
| 13 | Effects of exogenous short-chain N-acyl homoserine lactone on denitrifying process of Paracoccus denitrificans显示文摘N-acyl-homoserine lactones(AHLs) serve as quorum-sensing signals, which control a number of bacterial processes in many proteobacteria. Here we report the effects of exogenous short-chain AHL on the denitrifying process of Paracoccus denitrificans, which are capable of aerobic and anaerobic growth by utilizing nitrate. The denitrification activity of these cells was monitored by measuring denitrification products(including nitrate, nitrite,and nitrous oxide), and the individual messenger ribonucleic acid(m RNA) levels of nitrate,nitrite, nitric oxide and nitrous oxide reductases. The results indicated that 2 μmol/L C6-homoserine lactone(HSL) has little effect on cell density under either anaerobic or aerobic culture conditions, and the nitrate reduction activity appeared slightly affected by N-hexanoyl-DL-homoserine lactone(C6-HSL). However, exogenous C6-HSL significantly affected the transcription of nitrite reductase and nitric oxide reductase genes in P.denitrificans regardless of the presence of oxygen, and N_2O accumulation activity in P. denitrificans was suppressed by C6-HSL under aerobic condition. In contrast, exogenous C6-HSL stimulated the production of N_2O under anaerobic condition, suggesting that the regulation of denitrification by quorum sensing may be important in N_2O release. | Yun Cheng Yang Zhang Qiuxuan Shen Jie Gao Guoqiang Zhuang Xuliang Zhuang | 2017 | Journal of Environmental Sciences2017，29，4： | 6 |
| 14 | Room temperature ferromagnetism in ultra-thin van der Waals crystals of 1T-CrTe2显示文摘Although many emerging new phenomena have been unraveled in two dimensional(2D)materials with long-range spin orderings,the usually low critical temperature in van der Waals(vdW)magnetic material has thus far hindered the related practical applications.Here,we show that ferromagnetism can hold above 300 K in a metallic phase of 1T-CrTe2 down to the ultra-thin limit.It thus makes CrTe2 so far the only known exfoliated ultra-thin vdW magnets with intrinsic long-range magnetic ordering above room temperature.An in-plane room-temperature negative anisotropic magnetoresistance(AMR)was obtained in ultra-thin CrTe2 devices,with a sign change in the AMR at lower temperature,with−0.6%and+5%at 300 and 10 K,respectively.Our findings provide insights into magnetism in ultra-thin CrTe2,expanding the vdW crystals toolbox for future room-temperature spintronic applications. | Xingdan Sun Wanying Li Xiao Wang Qi Sui Tongyao Zhang Zhi Wang Long Liu Da Li Shun Feng Siyu Zhong Hanwen Wang Vincent Bouchiat Manuel Nunez Regueiro Nicolas Rougemaille Johann Coraux Anike Purbawati Abdellali Hadj-Azzem Zhenhua Wang Baojuan Dong Xing Wu Teng Yang Guoqiang Yu Bingwu Wang Zheng Han Xiufeng Han Zhidong Zhang | 2020 | Nano Research2020，13，12： | 6 |
| 15 | Microstructure and Mechanical Properties of Electron Beam Welded Titanium Alloy Ti-6246显示文摘Electron beam welding(EBW) was applied to a 10-mm-thick plate cut from Ti-6246 compressor disk.The microstructural characteristics, microhardness and room temperature tensile properties were investigated. Microstructure observations indicated that there existed plenty of thin needle-like α platelets studding in the matrix of the columnar β grains in the as-welded fusion zone(FZ). Post-weld heat treatment(PWHT) led to the precipitation of small secondary α platelets in the β matrix in heat affected zone and FZ. The thickness and the density of α platelets increased as the temperature of PWHT increased from545 to 645°C. The microhardness across the Ti-6246 EBW joint exhibited a nonuniform distribution. The hardness increased with the decrease of distance to the weld center, and reached the maximum of 467 HV in FZ when PWHT was carried out at 595°C. All the weldments tested with tension were fractured at the base material(BM) and exhibited a ductile fracture mode. The major deformation barrier in BM was the platelet α/β interfaces, however, the major deformation barrier in FZ was found to be β grain boundaries and secondary α/β interfaces. The BM with thicker platelet α phases had lower strength than the other two zones in the joint, and the BM deformed first and led to fracture in this zone. | Guoqiang Wang Zhiyong Chen Jinwei Li Jianrong Liu Qingjiang Wang Rui Yang | 2018 | Journal of Materials Science & Technology2018，34，3： | 6 |
| 16 | Buoyancy effect on heat transfer in rotating smooth square U-duct at high rotation number显示文摘The buoyancy effect on heat transfer in a rotating,two-pass,square channel is experimentally investigated in curent work.The classical copper plate technique is performed to measure the regional averaged heat transfer cofficients.In order to perform a fundamental research,all turbulators are removed away.Two approaches of altering Buoyancy numbers are selected:varying rotation number from 0 to 2.08 at Reynolds number ranges of 10000 to 70000,and varying inlet density ratio from 0.07 to 0.16 at Reynolds number of 10000.And thus,Buoyancy numbers range from 0 to 12.9 for both cases.According to the experimental results,the relationships between heat transfer and Buoyancy numbers are in accord with those obtained under different rotation numbers.For both leading and trailing surface,a critical Buoyancy number exists for each X/D location.Before the critical point,the effect of Buoyancy number on heat transfer is limited;but after that,the Nusselt number ratios show different increase rate.Given the same rotation number,higher wall temperature ratios with its corresponding higher Buoyancy numbers substantially enhance heat transfer on both passages.And the critical exceed-point that heat transfer from trailing surface higher than leading surface happens at the same Buoyancy number for different wall temperature ratios in the second passage.Thus,the stronger buoyancy effect promotes heat transfer enhancement at high rotation number condition. | Yang Li Guoqiang Xu Hongwu Deng Shuqing Tian | 2014 | Propulsion and Power Research2014，3，3： | 6 |
| 17 | Recombinant vaccine containing an RBD-Fc fusion induced protection against SARS-CoV-2 in nonhuman primates and mice显示文摘The novel coronavirus SARS-CoV-2 has infected more than 104 million individuals and resulted in more than 2.2 million deaths worldwide as of February 7,2021(http://gffzze7c39cdc9e894ca6sx6pkuww5o5fn60on.ffgz.tsg.suse.edu.cn).The COVID-19 pandemic highlights the need for safe and effective vaccines against SARS-CoV-2 infection. | Shihui Sun Lei He Zhongpeng Zhao Hongjing Gu Xin Fang Tiecheng Wang Xiaolan Yang Shaolong Chen Yongqiang Deng Jiangfan Li Jian Zhao Liang Li Xinwang Li Peng He Ge Li Hao Li Yuee Zhao Chunrun Gao Xiaoling Lang Xin Wang Guoqiang Fei Yan Li Shusheng Geng Yuwei Gao Wenjin Wei Zhongyu Hu Gencheng Han Yansong Sun | 2021 | Cellular & Molecular Immunology2021，18，4： | 5 |
| 18 | Genome wide abnormal DNA methylome of human blastocyst in assisted reproductive technology显示文摘Proper reprogramming of parental DNA methylomes is essential for mammalian embryonic development.However,it is unknown whether abnormal methylome reprogramming occurs and is associated with the failure of embryonic development.Here we analyzed the DNA methylomes of 57 blastocysts and 29 trophectoderm samples with different morphological grades during assisted reproductive technology(ART) practices.Our data reveal that the global methylation levels of high-quality blastocysts are similar(0.30 ± 0.02,mean ± SD).while the methylation levels of low-quality blastocysts are divergent and away from those of high-quality blastocysts.The proportion of blastocysts with a methylation level falling within the range of 0.30 ± 0.02 in different grades correlates with the live birth rate for that grade.Moreover,abnormal methylated regions are associated with the failure of embryonic development.Furthermore,we can use the methylation data of cells biopsied from trophectoderm to predict the blastocyst methylation level as well as to detect the aneuploidy of the blastocysts.Our data indicate that global abnormal methylome reprogramming often occurs in human embryos,and suggest that DNA methylome is a potential biomarker in blastocyst selection in ART. | Guoqiang Li Yang Yu Yong Fan Congru Li Xiaocui Xu Jialei Duan Rong Li Xiangjin Kang Xin Ma Xuepeng Chen Yuwen Ke Jie Yan Ying Lian Ping Liu Yue Zhao Hongcui Zhao Yaoyong Chen Xiaofang Sun Jianqiao Liu Jie Qiao Jiang Liu | 2017 | Journal of Genetics and Genomics2017，44，10： | 5 |
| 19 | China under Uncertainty: Outlook, Counterfactual and Policy Simulations, and Reform Implementation--A Summary of Annual Report (2016-2017)显示文摘当面对时,瓷器 macroeconomy 被增加的无常包围坚持向下压力进入年 2017。主要外部挑战被混乱政治气候和混乱撤退从喂的率步行的伴有逼近的 US 的全球化强加,它可以触发破坏贸易战争并且对 RMB 跌价和撤资施加压力。在主要内部挑战仍然保持根深蒂固高压封锁风险在根本上增强债层次,和更多中从房地产部门和胀大的住房市场水泡的过多的 financialization 被积累,在在在资源分配的市场上的管理的一般经济和优势的继续的 off-real-to-virtual 运动。基于 IAR-CMM 模型,它考虑轮转、世俗的因素,基线真实 GDP 生长率被投射在 2017 是 6.5%( 而不是正式数据可靠的 6.13% 使用更多) 。Counterfactual 分析和政策模拟也被进行加亮包围瓷器 macroeconomy 的旋绕的无常。通过这些分析的透镜,我们作为固执地弄歪的经济结构识别弱眼界的一个根原因由于拖延在里面机构和统治改过,它不仅损害瓷器生长潜力而且当加重他们的副作用时,限制它的最近的刺激政策的权力。在面临不利地发展人口分布时的成功的经济重构的钥匙是面向市场的改革,与平衡短期的稳定和长期间开发的设计得好的策略。如此的改革应该向现代自由市场经济和规章的状态在瓷器转变保持中心舞台。 | Kevin X. D. Huang Guoqiang Tian Yibo Yang | 2017 | Frontiers of Economics in China-Selected Publications from Chinese Universities2017，12，2： | 5 |
| 20 | Facile fabrication of micro-grooves based photonic crystals towards anisotropic angle-independent structural colors and polarized multiple reflections显示文摘In nature,many living organisms exhibit low-angle-dependent or even angle-independent structural colors for wide viewing angle,such as the blue skin of mandrill,feather of blue bird and shell of longhorn beetle,etc.To mimic these structural colors,based on periodic semicircular micro-grooved(PSMG) substrate,silica colloidal photonic crystals provide anisotropic angle-independent structural colors.The PSMG photonic crystals were fabricated by self-assembling monodispersed silica nanoparticles on a micro-grooved template,which can be easily prepared in large scale by a hot embossing method,and no additional materials are needed in the whole preparation process.The PSMG photonic crystals exhibit identical structural colors around the groove axis,whereas it is angle-dependent along the groove axis.In addition,this PSMG surface of photonic crystal also leads to color separation effect and monocolor polarization conversion.This system provides a facile and scalable means to prepare anisotropically angleindependent colloidal photonic crystal,which is considered important in applications in the field of anti-counterfeiting or the manufacture of monochromatic light reflector with wide viewing angles and other novel optical devices. | Chuanyong Liu Yue Long Bingquan Yang Guoqiang Yang Chen-Ho Tung Kai Song | 2017 | Science Bulletin2017，62，13： | 5 |
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