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	题名	作者	年代	出处	被引量
1	Not interferon, but interleukin‐6 controls early gene expression in hepatitis B virus infection显示文摘	Marianna H?sel Maria Quasdorff Katja Wiegmann Dennis Webb Uta Zedler Mathias Broxtermann Raindy Tedjokusumo Knud Esser Silke Arzberger Carsten J. Kirschning Anja Langenkamp Christine Falk Hildegard Büning Stefan Rose‐John Ulrike Protzer	2009	Hepatology2009，，6：	3
2	Docosahexaenoic acid suppresses arachidonic acid-induced proliferation of LS-174T human colon carcinoma cells显示文摘AIM:To investigate the impact of arachidonic acid (AA) and docosahexaenoic acid (DHA) and their combination on colon cancer cell growth.METHODS:The LS-174T colon cancer cell line was used to study the role of the prostaglandin precursor AA and the omega-3 polyunsaturated fatty acid DHA on cell growth. Cell viability was assessed in XTT assays. For analysis of cell cycle and cell death,flow cytometry and DAPI staining were applied. Expression of cyclooxygenase-2 (COX-2),p21 and bcl-2 in cells incubated with AA or DHA was examined by real-time RT-PCR. Prostaglandin E2 (PGE2) generation in the presence of AA and DHA was measured using a PGE2-ELISA.RESULTS:AA increased cell growth,whereas DHAreduced viability of LS 174T cells in a time-and dose-dependent manner. Furthermore,DHA down-regulated mRNA of bcl-2 and up-regulated p21. Interestingly,DHA was able to suppress AA-induced cell proliferation and significantly lowered AA-derived PGE2 formation. DHA also down-regulated COX-2 expression. In addition to the effect on PGE2 formation,DHA directly reduced PGE2-induced cell proliferation in a dose-dependent manner. CONCLUSION:These results suggest that DHA can inhibit the pro-proliferative effect of abundant AA or PGE2.	Piet Habbel Karsten H Weylandt Katja Lichopoj Johannes Nowak Martin Purschke Jing-Dong Wang Cheng-Wei He Daniel C Baumgart Jing X Kang	2009	World Journal of Gastroenterology2009，15，9：	2
3	Genotype-dependent activation or repression of HBV enhancer Ⅱ by transcription factor COUP-TF1显示文摘AIM: To study the expression of HBV enhancer Ⅱ by transcription factor COUP-TF1. METHODS: In order to study the regulation of HBV variants in the vicinity of the NRRE we cloned luciferase constructs containing the HBV enhancer Ⅱ from variants and from HBV genotypes A and D and cotransfected them together with expression vectors for COUP-TF1 into HepG2 cells. RESULTS: Our fi ndings show that enhancer Ⅱ of HBV genotype A is also repressed by COUP-TF1. In contrast, two different enhancer Ⅱ constructs of HBV genotype D were activated by COUP-TF1. The activation was independent of the NRRE because a natural variant with a deletion of nt 1763-1770 was still activated by COUP- TF1. CONCLUSION: Regulation of transcription of the HBV genome seems to differ among HBV genomes derived from different genotypes. These differences in transcriptional control among HBV genotypes may be the molecular basis for differences in the clinical course among HBV genotypes.	Silke F Fischer Katja Schmidt Nicola Fiedler Dieter Glebe Christian Schüttler Jianguang Sun Wolfram H Gerlich Reinald Repp Stephan Schaefer	2006	World Journal of Gastroenterology2006，12，37：	2
4	Confirmation of tubal patencyin hysterosalpingo -contrast sonography by transvaginalhydrolaparoscopy 显示文摘	Katja M Heini H Helena T	2009	Acta Obstet Gynecol2009，88，3：	1
5	Developmental outcome and psychosocial adjustment in children after surgery for congenital heart disease during infancy 显示文摘	Katja H Karl - Otto D Herman K	2007	SRIP2007，25，2：	1
6	Cephalometric characteristics of Class 2 division 2 malocclusion : A comparative study in children 显示文摘	Pancherz D Katja Z Britta H	2007	An- gle Orthod2007，67，2：	1
7	Clinical utility of cytokeratins as tumor markers 显示文摘	Barak V Goike H Katja W	2004	Clinical Biochemistry2004，37，：	1
8	The validity of air and salinehysterosalpingo-contrast sonography in tubal patency inves-tigation before insemination treatment显示文摘	Katja AH Heini H Helena T	2007	Eur J Obstet GynReprad Biol2007，132，1：	1
9	Safety and toxicity of intrathecal liposomal cytarabine ( Depocyte ) in children and adolescents with recurrent or refractory brain tumors:a multi-institutional retrospective study显示文摘	Martin B Nele S Katja yon H	2009	Anti-Cancer Drugs2009，11，9：	1
10	Separation of saturated and unsaturated fatty acid by capillary electrophoresis and HPLC显示文摘	Katja H Frank H Suasann M	1998	American Laboratory1998，30，10：	1
11	Generation and characterization of cDNA clones from Sarcoptes scabiei varhominis for an expressed sequence tag library:iden- tification of homologues of house dust mite allergens 显示文摘	Katja F Deborah C H Pearly H	2003	Am J Trop Med Hyg2003，68，1：	1
12	Plasma carotenoids and vitamin C concentrations and risk of urothelial cell carcinoma in the European Prospective Investigation into Cancer and Nutrition12345显示文摘	Martine M Ros H Bas Bueno-de-Mesquita Ellen Kampman Katja KH Aben Frederike L Büchner Eugene HJM Jansen Carla H van Gils Lars Egevad Kim Overvad Anne Tj?nneland Nina Roswall Marie Christine Boutron-Ruault Marina Kvaskoff Florence Perquier Rudolf Kaaks Jen	2012	American Journal of Clinical Nutrition2012，，4：	1
13	Quality components of sea buckthom (Hippophae rhamnoides) varieties显示文摘	KATJA M T MARI A H HEIKKI P K	2005	Journal of Agricultural and Food Chemistry2005，53，5：	1
14	Glanzmann thrombasthenia Frankfurt I is associated with a point mutation Thr176I1e in the N-terminal region of αⅡb subunit integrin 显示文摘	Westrup D Santoso S Katja F H	2004	Thromb Haemost2004，92，5：	1
15	DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer显示文摘	Kathrin Mutze Rupert Langer Felix Schumacher Karen Becker Katja Ott Alexander Novotny Alexander Hapfelmeier Heinz H?fler Gisela Keller	2011	European Journal of Cancer2011，，12：	1
16	Prognostic Significance of Free Peritoneal Tumor Cells in the Peritoneal Cavity Before and After Neoadjuvant Chemotherapy in Patients with Gastric Carcinoma Undergoing Potentially Curative Resection显示文摘	Sylvie Lorenzen Benjamin Panzram Robert Rosenberg Hjalmar Nekarda Karin Becker Ulrich Schenk Heinz H?fler J?rg-Rüdiger Siewert Dirk J?ger Katja Ott	2010	Annals of Surgical Oncology2010，，10：	1
17	Determination of cationic surfacrants by capillary electrophoresis with indirect photometric detection 显示文摘	KATJA H CARLA V GERHARD W	1997	Journal of Chromatography A1997，781，12：	1
18	Near-field investigations of nanoshell cylinder dimers显示文摘	H Katja G Ulrich C Silke	2009	The Journal of Chemical Physics2009，131，16：	1
19	Suppression of hepatitis B virus enhancer 1 and 2 by hepatitis C virus core protein显示文摘	Christian G Schüttler Nicola Fiedler Katja Schmidt Reinald Repp Wolfram H Gerlich Stephan Schaefer	2002	Journal of Hepatology2002，，6：	1
20	Cephalometric characteristics of Class Ⅱ division 2 malocclusion:A comparative study in children显示文摘	Pancherz D Katja Z Britta H	1997	Angle Orthod1997，67，2：	1

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