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32篇 您的检索式:作者名="Haiyang Fan"
    题名 作者 年代 出处 被引量
1Minimal invasive microscopic tooth preparation in esthetic restoration: a specialist consensus显示文摘By removing a part of the structure,the tooth preparation provides restorative space,bonding surface,and finish line for various restorations on abutment.Preparation technique plays critical role in achieving the optimal result of tooth preparation.With successful application of microscope in endodontics for>30 years,there is a full expectation of microscopic dentistry.However,as relatively little progress has been made in the application of microscopic dentistry in prosthodontics,the following assumptions have been proposed:Is it suitable to choose the tooth preparation technique under the naked eye in the microscopic vision?Is there a more accurate preparation technology intended for the microscope?To obtain long-term stable therapeutic effects,is it much easier to achieve maximum tooth preservation and retinal protection and maintain periodontal tissue and oral function health under microscopic vision?Whether the microscopic prosthodontics is a gimmick or a breakthrough in obtaining an ideal tooth preparation should be resolved in microscopic tooth preparation.This article attempts to illustrate the concept,core elements,and indications of microscopic minimally invasive tooth preparation,physiological basis of dental pulp,periodontium and functions involved in tool preparation,position ergonomics and visual basis for dentists,comparison of tooth preparation by naked eyes and a microscope,and comparison of different designs of microscopic minimally invasive tooth preparation techniques.Furthermore,a clinical protocol for microscopic minimally invasive tooth preparation based on target restorative space guide plate has been put forward and new insights on the quantity and shape of microscopic minimally invasive tooth preparation has been provided.Haiyang Yu Yuwei Zhao Junying Li Tian Luo Jing Gao Hongchen Liu Weicai Liu Feng Liu Ke Zhao Fei Liu Chufan Ma Juergen MSetz Shanshan Liang Lin Fan Shanshan Gao Zhuoli Zhu Jiefei Shen Jian Wang Zhimin Zhu Xuedong Zhou 2019International Journal of Oral Science2019,11,4:25
2A cyclic nucleotide-gated channel mediates cytoplasmic calcium elevation and disease resistance in rice显示文摘The transient elevation of cytoplasmic calcium is essential for pathogen-associated molecular pattern(PAMP)-triggered immunity(PTI).However,the calcium channels responsible for this process have remained unknown.Here,we show that rice CDSI(CELL DEATH and SUSCEPTIBLE to BLAST 1)encoding OsCNGC9;a cyclic nucleotide-gated channel protein,positively regulates the resistance to rice blast disease.We show that OsCNGC9 mediates PAMP-induced Ca2+influx and that this event is critical for PAMPs-triggered ROS burst and induction of PTI-related defense gene expression.We further show that a PTI related receptor-lih cytoplasmic kinase OsRLCK185 physically interacts with and phosphorylates OsCNGC9 to activate its channel activity.Our results suggest a signaling cascade linking pattern recognition to calcium channel activation,which is required for initiation of PTI and disease resistance in rice.Jiachang Wang Xi Liu An Zhang Yulong Ren Fuqing Wu Gang Wang Yang Xu Cailin Lei Shanshan Zhu Tian Pan Yongfei Wang Huan Zhang Fan Wang Yan-Qiu Tan Yupeng Wang Xin Jin Sheng Luo Chunlei Zhou Xiao Zhang Jinling Liu Shuai Wang Lingzhi Meng Yihua Wang Xi Chen Qibing Lin Xin Zhang Xiuping Guo Zhijun Cheng Jiulin Wang Yunlu Tian Shijia Liu Ling Jiang Chuanyin Wu Ertao Wang Jian-Min Zhou Yong-Fei Wang Haiyang Wang Jianmin Wan 2019Cell Research2019,29,10:13
3Onco-miR-24 regulates cell growth and apoptosis by targeting BCL2L11 in gastric cancer显示文摘胃的癌症是世界范围的最普通的恶意之一;然而,在 tumorigenesis 的分子的机制仍然需要探索。BCL2L11 属于 BCL-2 家庭,并且充当内在的 apoptotic 串联的一个中央管理者并且调停房间 apoptosis。尽管 miRNAs 被报导了涉及癌症开发的每个阶段,在 GC 的 miR-24 的角色还没被报导。在现在的学习,当 BCL2L11 的表示在 GC 的肿瘤纸巾被禁止时, miR-24 被发现起来调整。研究从在 vitro 并且在显示出的 vivo,那 miR-24 调整 BCL2L11 表示由与 mRNA 的 3UTR 直接有约束力,因此支持房间生长,移植当禁止房间 apoptosis 时。因此, miR-24 是能是为未来的潜在的药目标的新奇 onco-miRNA 临床的使用。Haiyang Zhang Jingjing Duan Yanjun Qu Ting Deng Rui Liu Le Zhang Ming Bai Jialu Li Tao Ning Shaohua Ge Xia Wang ZhenzhenWang~ Qian Fan Hongli Li Guoguang Ying Dingzhi Huang Yi Ba 2016Protein & Cell2016,7,2:11
4Bushen Yisui Capsule ameliorates axonal injury in experimental autoimmune encephalomyelitis显示文摘A preliminary clinical study by our group demonstrated Bushen Yisui Capsule(formerly called Erhuang Formula)in combination with conventional therapy is an effective prescription for the treatment of multiple sclerosis.However,its effect on axonal injury during early multiple sclerosis remains unclear.In this study,a MOG35–55-immunized C57BL/6 mouse model of experimental autoimmune encephalomyelitis was intragastrically administered Bushen Yisui Capsule.The results showed that Bushen Yisui Capsule effectively improved clinical symptoms and neurological function of experimental autoimmune encephalomyelitis.In addition,amyloid precursor protein expression was down-regulated and microtubule-associated protein 2 was up-regulated.Experimental findings indicate that the disease-preventive mechanism of Bushen Yisui Capsule in experimental autoimmune encephalomyelitis was mediated by amelioration of axonal damage and promotion of regeneration.But the effects of the high-dose Bushen Yisui Capsule group was not better than that of the medium-dose and low-dose Bushen Yisui Capsule group in preventing neurological dysfunction.Ling Fang Qi Zheng Tao Yang Hui Zhao Qiuxia Zhang Kangning Li Li Zhou Haiyang Gong Yongping Fan Lei Wang 2013Neural Regeneration Research2013,8,35:6
5miR-10a inhibits cell proliferation and promotes cell apoptosis by targeting BCL6 in diffuse large B-cell lymphoma显示文摘BCL6 (B 房间淋巴瘤 6 ) 基因是经常在弥漫的大 B 房间淋巴瘤(DLBCL ) 被表示的 proto-oncogene。功能的 BCL6 损失能杀死 DLBCL 房间,证明 BCL6 为 DLBCL 房间的幸存是必要的并且能是一个治疗学的目标。在这研究,我们发现那 BCL6 蛋白质层次,建议那是一致地在 DLBCL 纸巾的 upregulated 而它的 mRNA 层次在纸巾随机变化了, post-transcriptional 机制涉及 BCL6 规定。我们使用了生物信息学分析寻找 miRNAs,它潜在地指向 BCL6,并且在 BCL6 的 3-untranslated 区域(3-UTR ) 为 miR-10a 识别了特定的指向的地点。我们进一步鉴别在 miR-10a 层次和 BCL6 蛋白质层次之间的反的关联,然而并非 mRNA 铺平,在 DLBCL 肿瘤织物样品。由 overexpressing 或在 DLBCL 房间将 miR-10a 击倒,我们试验性地直接验证了那 miR-10a 认出 BCL6 抄本和调整 BCL6 表示的 3-UTR。而且,我们证明否定地由 miR-10a 调整 BCL6 压制了增长并且支持了 DLBCL 房间的 apoptosis。Qian Fan Xiangrui Meng Hongwei Liang Huilai Zhang Xianming Liu Lanfang Li Wei Li Wu Sun Haiyang Zhang Ke Zen Chen-Yu Zhang Zhen Zhou Xi Chen Yi Ba 2016Protein & Cell2016,7,12:5
6Gene-lndexed Mutations in Maize显示文摘Xiaoduo Lu Jisheng Liu Wen Ren Qun Yang Zhenguang Chai Rumei Chen Lei Wang Jun Zhao Zhihong Lang Haiyang Wang Yunliu Fan Jiuran Zhao Chunyi Zhang 2018Molecular Plant2018,11,3:4
7Room-temperature production of silver-nanofiber film for large-area, transparent and flexible surface electromagnetic interference shielding显示文摘A kind of pollution known as electromagnetic interference(EMI),which results from ubiquitous usage of various electronic communication and military radar equipment,has been receiving increasing attention recently.However,large-area EMI shielding on transparent and/or curved surfaces,including building windows,curved glass wall,and special requirements spaces(SRSs),remains hard to achieve.In this paper,a silver nanofiber(AgNF)based flexible and transparent EMI shielding film was successfully assembled via a room-temperature roll-to-roll production method.For transparent application scenario,AgNF with 89%transmittance in visible range and 1μm thickness shows~20 dB shielding efficiency(EMI SE).On the other hand,total shielding(>50 dB)is obtained when the thickness of AgNF increases to 10μm,while its transmittance in visible range remains higher than 75%.Considering the facile and scale-free production technology,this material can be readily applied in large-scale,transparent,and/or SRSs EMI shielding.Sen Lin Haiyang Wang Fan Wu Qingmin Wang Xiaopeng Bai Di Zu Jianan Song Dong Wang Zhenglian Liu Ziwei Li Nian Tao Kai Huang Ming Lei Bo Li Hui Wu 2019npj Flexible Electronics2019,3,1:4
8Effect of erhuangfang on cerebral and spinal demyelination and regeneration as well as expression of glial fibrillary acidic protein in rats with experimental allergic encephalomyelitis显示文摘BACKGROUND: It demonstrates that erhuangfang can improve clinical symptoms of multiple sclerosis and relieve side effects of hormone. However, whether erhuangfang can improve experimental allergic encephalomyelitis (EAE) or not needs a further study. OBJECTIVE: To observe the effect of erhuangfang on neuro-pathology and astrocyte in EAE rats and compare with the effect of hormone. DESIGN: Randomized controlled animal study. SETTINGS: Department of Traditional Chinese Medicine, Beijing Tiantan Hospital, Capital Medical University; College of Traditional Chinese Medicine, Capital Medical University. MATERIALS: The experiment was carried out in the Laboratory Center of Capital Medical University from August to October 2005. Ten adult guinea pigs (SPF grade, weighing 400-450 g) and 70 adult Lewis rats (SPF grade, weighing 200-220 g) were selected in this study. Erhuangfang consisted of jiudahuang, shengdi, shuizhi, dabeimu, etc. METHODS: ① Experimental intervention: Rats were randomly divided into normal group (n=10), model group (n=20), western medicine group (n=20) and Chinese herb group (n=20). Mixed emulsion, which was consisted of Freund's adjuvant and spinal cord homogenate of guinea pigs, was subcutaneously injected into palms of the two hindfeet of rats in the latter three groups to establish EAE models. Foot pads were injected with saline and then rats were perfused with saline in the normal group. In the model group, models were established as the same as those mentioned above, and rats were also perfused with saline. Rats in the western medicine group were perfused with saline and then 5 mg/kg prednisone acetate suspension. Rats in the Chinese herb group were perfused with erhuangfang decoction (15 g raw materials per kilogram) at 5 days before model establishment. The dosage in the four groups was 3 mL/day per rat. ② Experimental evaluation: At 28 days after model establishment, rats were randomly selected for cerebral (mainly surrounding cerebral ventricle) and spinal cord (cervical enlargement and lumbar enlargement) collections, and then haematine-eosin (HE) staining and SLG myelin staining were used to observe demyelination and regeneration; meanwhile, immunohistochemical staining was used to observe the expression of glial fibriliary acidic protein (GFAP). MAIN OUTCOME MEASURES: Cerebral and spinal demyelination and regeneration as well as expression of GFAP in EAE rats. RESULTS: All 70 Lewis rats were involved in the final analysis. ① Demyelination and regeneration: Infiltration of inflammatory cells surrounding cerebrum and small venous vessels of spinal cord white matter, demyelination surrounding vessels and plentiful foam cells at myelinolysis sites were observed in the model group. Symptoms were relieved in the western medicine group and the Chinese herb group as compared with those in the model group. While, numbers of inflammatory infiltrated cells and vascular cuffs were decreased in focal region as compared with those in the model group; in addition, areas of softening focus and demyelination were decreased. ② Expression of GFAP: Volumes and numbers of positive cells of GFAP in white matter region were respectively bigger and higher than those of normal cells in the model group. Plentiful positive cells of GFAP were disorderly aggregated in hippocampus and surrounding small vessel cuffs. While, expression of GFAP was mildly increased surrounding focus in the Chinese herb group; however, GFAP did not express surrounding focus in the western medicine group. In addition, expressions of GFAP were not increased in non-focal region in both Chinese herb group and western medicine group. CONCLUSION: Both erhuangfang and hormone can relieve inflammatory reaction of central nervoussystem and demyelination of EAE rats. On one hand, erhuangfang can regulate reaction of astrocyte in two ways, relieve reaction and proliferation of astrocyte in non-focal region and maintain the protective effect of astrocyte on brain tissue in focal region; on the other hand, hormone can overall inhibit reaction of astrocyte.Xiuzhen Liu Yongping Fan Lei Wang Yun Cui Haiyang Gong 2007Neural Regeneration Research2007,2,8:4
9Evaluation of Molecular Structural Effects on Needle Coke Mesophase Stacking显示文摘Molecular simulations were performed to investigate the molecular structural effects on needle coke mesophase stacking.The simulation results showed that the stacking states of anthracene trimer and tetramer accumulations were orderly,while the stacking states of anthracene dimer,pentamer,and hexamer accumulations were disorderly.Anthracene trimer and tetramer in the model compounds were two of the most ideal needle coke mesophase constituents.It was also found that the introduction of methyl side chains in anthracene trimer derivatives was not conducive to the formation of a mesophase crystal.To sum up,the molecules which had similar structures to anthracene trimer or tetramer with no alkyl chains are ideal constituents of needle coke mesophase.Yang Haiyang Wang Chunlu Zhou Han Wang Lixin Ren Qiang Fan Qiming 2020China Petroleum Processing & Petrochemical Technology2020,22,3:3
10A Blockchain-Based Flexible Data Auditing Scheme for the Cloud Service显示文摘Nowdays, cloud storage technology has become a hot topic, and an increasing number of users are concerned with the security of their data in the cloud.Many auditing schemes on the cloud are proposed and the introduction of a third-party auditor to assist users in verifying the integrity of cloud data. As a centralized node, the third-party auditor has to communicate with all cloud users and cloud service providers, which becomes the bottleneck of the whole scheme. To solve this problem,we design a blockchain-based flexible cloud data auditing scheme. In our scheme, a decentralized auditing framework is proposed to eliminate the dependency on the thirdparty auditor, which increases the stability, security and performance of the whole scheme. Since the cloud service provider can automatically generates auditing proofs, our scheme can relieve the communication burdens of the cloud service provider. The proposed scheme also adapts the Merkle Hash tree to improve the verification performance.Security analysis and experiments show that the proposed scheme is secure and has better stability and verification efficiency.FAN Kefeng LI Fei YU Haiyang YANG Zhen 2021Chinese Journal of Electronics2021,30,6:3
11Two pathogenesis-related proteins interact with leucine-rich repeat proteins to promote Alternaria leaf spot resistance in apple显示文摘Alternaria leaf spot in apple(Malus x domestica),caused by the fungal pathogen Alternaria alternata f.sp.mali(also called A.mali),is a devastating disease resulting in substantial economic losses.We previously established that the resistance(R)protein MdRNL2,containing a coiled-coil,nucleotide-binding,and leucine-rich repeat(CC R-NB-LRR)domain,interacts with another CC R-NB-LRR protein,MdRNL6,to form a MdRNL2–MdRNL6 complex that confers resistance to A.mali.Here,to investigate the function of the MdRNL2–MdRNL6 complex,we identified two novel pathogenesis-related(PR)proteins,MdPR10-1 and MdPR10-2,that interact with MdRNL2.Yeast two-hybrid(Y2H)assays and bimolecular fluorescence complementation(BiFC)assays confirmed that MdPR10-1 and MdPR10-2 interact with MdRNL2 and MdRNL6 at the leucine-rich repeat domain.Transient expression assays demonstrated that accumulation of MdPR10-1 and MdPR10-2 enhanced the resistance of apple to four strains of A.mali that we tested:ALT1,GBYB2,BXSB5,and BXSB7.In vitro antifungal activity assays demonstrated that both the proteins contribute to Alternaria leaf spot resistance by inhibiting fungal growth.Our data provide evidence for a novel regulatory mechanism in which MdRNL2 and MdRNL6 interact with MdPR10-1 and MdPR10-2 to inhibit fungal growth,thereby contributing to Alternaria leaf spot resistance in apple.The identification of these two novel PR proteins will facilitate breeding for fungal disease resistance in apple.Qiulei Zhang Chaoran Xu Haiyang Wei Wenqi Fan Tianzhong Li 2021Horticulture Research2021,8,1:2
12The circFASN/miR-33a pathway participates in tacrolimusinduced dysregulation of hepatic triglyceride homeostasis显示文摘Dyslipidemia exhibits a high incidence after liver transplantation,in which tacrolimus,a widely used immunosuppressant,plays a fundamental role.MicroRNAs and related circRNAs represent a class of noncoding RNAs that have been recognized as important regulators of genes associated with lipid metabolism.However,their transcriptional activities and functional mechanisms in tacrolimus-related dyslipidemia remain unclear.In this study,we observed that tacrolimus could induce triglyceride accumulation in hepatocytes by stimulating sterol response element-binding proteins(SREBPs)and miR-33a.Our in silico and experimental analyses identified miR-33a as a direct target of circFASN.Tacrolimus could downregulate circFASN and result in elevated miR-33a in vivo and in vitro.Overexpression of circFASN or silencing of miR-33a decreased the promoting effects of tacrolimus on triglyceride accumulation.Clinically,the incidence of dyslipidemia in liver transplant recipients with elevated serum miR-33a after liver transplantation was higher than that in patients without elevated serum miR-33a(46.3%vs.18.8%p=0.012,n=73).Our results showed that the circFASN/miR-33a regulatory system plays a distinct role in tacrolimus-induced disruption of lipid homeostasis.MiR-33a is likely a risk factor for tacrolimus-related dyslipidemia,providing a potential therapeutic target to combat tacrolimus-induced dyslipidemia after liver transplantation.Chenzhi Zhang Kangchen Chen Rongli Wei Guanghan Fan Xuechun Cai Li Xu Beini Cen Jianguo Wang Haiyang Xie Shusen Zheng Xiao Xu 2020Signal Transduction and Targeted Therapy2020,5,1:2
13Inhomogeneous deformation of {111} grain in cold rolled tantalum显示文摘The microstructures of {111} grain were characterized in detailed and systematically investigated with the aid of electron backscatter diffraction(EBSD) and transmission electron microscope(TEM). The stored energy in different regions in the grain was evaluated by the band contrast values collected from EBSD. The results show that the distribution of energy is inhomogeneous through the grain. Especially,the regions containing the least and the largest energy were extracted from the EBSD data, and then quantitatively analyzed based on the misorientation and Schmid factor. Many peaks with large misorientation appeared in the region containing larger energy, and these peaks represent the existences of micro-bands and micro-shear bands in {111} grain. The results of Schmid factor suggest that the region containing larger energy is prone to deforming ahead of the region with less stored energy, implying the more serious subdivision of the microstructure of region with larger stored energy.Yahui Liu Shifeng Liu Chao Deng Haiyang Fan Xiaoli Yuan Qing Liu 2018Journal of Materials Science & Technology2018,34,11:2
14The Grey-backed Shrike parents adopt brood survival strategy in both the egg and nestling phases显示文摘Background:Great diversity exists in the parenting pattern of altricial birds,which has long been considered as an adaptive response to specific environmental conditions but not to their life-history style.Methods:We examined the egg-laying and nestling-raising pattern of the Grey-backed Shrike(Lanius tephronotus)that breeds only once a year on the Tibetan Plateau.We compared the dietary composition to that of its sympatric competitor,the Brown-cheeked Laughing Thrush(Trochalopteron henrici)that breeds twice a year.Results:Female Grey-backed Shrikes produced a fixed clutch size of five,with increasing egg size by their laying sequence.The last offspring in the brood is disadvantageous in the size hierarchy because it hatches later.However,they had the largest fledgling body mass.These findings indicate that Grey-backed Shrikes adopt the brood survival strategy in both the egg and nestling phases.Moreover,males and females exhibit no sexual division in providing parental care as they made an equal contribution to the total amount of food delivered to their brood.This parenting pattern of Grey-backed Shrikes,as well as their dietary items,differ significantly from those of the Brown-cheeked Laughing Thrush.Conclusions:We suggest that the differentiation in life-history style between sympatric competitors,rather than a behavioral response to specific environmental conditions,plays a decisive role in driving avian parenting strategy diversification.Liqing Fan Lifang Gao Zhenqin Zhu Xiaodan Zhang Wen Zhang Haiyang Zhang Jianchuan Li Bo Du 2021Avian Research2021,12,1:1
15Laser-induced damage of a 1064-nm ZnS/MgF2 narrow-band interference filter显示文摘Haiyang Hu Zhengxiu Fan Fu Luo 2001Applied Optics2001,40,12:1
16A novel approach to the attitude stabilization structure for ducted-fan operative aerial robots:Finding improvements for modeling error and strong external transient disturbance显示文摘This research concerns a novel attitude stabilization structure for a ducted-fan aerial robot to work against modeling error and strong external transient disturbance,and it focuses on two main control targets:modeling error compensation,and the improvement of disturbance resistance along the rolling channel.For the first research objective,we proposed an adaptive nominal controller with the reconfigurable control law design based on the estimation of the modeling error found in the closed-loop.Results of simulations and corresponding flight tests verified that the proposed adaptive control structure is robust against both constant and time-varying modeling error.For the other research objective,a SAC(Stability Augmentation Control)structure was devised based on the CMG(Control Moment Gyroscope)theory in order to provide extra moment which effectively withstands the transient disturbance beyond the CDG(Critical Disturbance Gain).Furthermore,we studied the corresponding controller for the SAC via the SMC(sliding mode control)theory,while the working mechanism and performance of the SAC were verified through a specially devised prototype.Wei FAN Bin XU Changle XIANG Yibo ZHANG Haiyang YANG 2022Chinese Journal of Aeronautics2022,35,2:1
17Laser-induced damage of a 1 064 nm ZnS/MgF2 narrow-band interference filter显示文摘Hu Haiyang Fan Zhengxiu Luo Fu 2001Appl Opt2001,40,12:1
18Jupiter system exploration trajectory design: Summary of the winning solution at CTOC10显示文摘This paper presents the methods and results submitted by the winning team from Harbin Institute of Technology of the 10th China Trajectory Optimization Competition(CTOC10).The problem posed by CTOC10 requires exploring the Jupiter system using a combined spacecraft.The exploration mission consists of the detection of Jupiter’s magnetic field and an exploration of the Galilean moons.The mission is completed through three steps:problem analysis,orbital design process,and data processing.The orbital design process is mainly divided into four parts,namely,repeating groundtrack orbit design,gravity-assisted orbit design,initial orbit parameter selection,and local optimization adjustment.The designed orbit is then evaluated using a heuristic optimization algorithm applied during the data processing.Finally,six full-coverage observations of Jupiter’s magnetic field are realized under the constraints of fuel and time.The final index of the submitted result is 357.8067.Haiyang Zhang Yabo Hu Zichen Fan Jie Lv Huidong Ma Ze Yu Mingying Huo Gang Zhang 2021Astrodynamics2021,5,1:1
19Seed,cutting and air-layering reproductive inefficiency of noxious woody vine Merremia biosiana and its implications for management strategy显示文摘Merremia boisiana(Gagnep)van Ooststr.is a noxious fast growing woody vine and is able to grow overtop other plants,causing the death of plants underneath and forming monospecies stands.To formulate management responses,we assessed its seed and vegetative reproduction efficacy through indoor and field experiments.The number of flowers counted from bagged infructescences in Guangzhou ranged from 25 to 172,with an average of 80.80.Counting the seeds of bagged infructescences had shown that there were only 1.58 hard testa seeds in each infructescence.Seed vitality tests using red ink indicated that only 68.6%of hard testa and filled seeds were viable.The emergence rate of scarified hard testa seeds in the sand bed was 31.96%.Under imitated natural conditions,8%of hard testa seeds could germinate,and 9%still retained their germination potential in one year.Thus,seedlings should be monitored and removed in a timely fashion after any attempt of clearing.Moving soil or transplanting plant from infested patches should be strictly prohibited at least for several years.All considered,an infructescence contributed 0.3 seedlings.The investigation in the field found no seedlings either inside or at the perimeter of the patch,suggesting scant expansion by means of seed dispersal.Therefore,the elimination effort could be focused on a relatively restricted scale of patches.Of 630 cuttings of young shoots,old shoots and old lying shoots with or without growth regulators,there were only four(or 0.63%)established individuals.Air-layering shoots all died in two months.Poor cuttings and airlayering reproduction indicated that regeneration from fragments of removed stems or accidentally dropped ones was quite unlikely,and thus mechanical removal was safe.Mingguang LI Haiyang LIU Fenglan LI Xiuyuan CHENG Bin GUO Zhiwei FAN 2009Frontiers in Biology2009,4,3:1
20Photodynamic Therapy Activities of 10-(4-Formylphenyl)-5,15-bis(pentafluorophenyl)corrole and Its Gallium Complex显示文摘10-(4-Formylphenyl )-5,15-bis(pentafluorophenyl)corrole 1 并且它的镓建筑群 1-Ga 被用来在肝癌症(BEL-7402 ) 调查他们的 photocytotoxicity,肺癌症(A549 ) 和颈的癌症(Siha, Hela ) 房间线。在所有测试肿瘤房间之中, Siha 肿瘤房间对光力学的治疗(太平洋夏季时间) 最敏感在 1 的治疗和 1-Ga。1 的太平洋夏季时间 IC 50 和向 Siha 肿瘤房间的 1-Ga 分别地到达 1.3 和 0.8  µmol/L,它比 cisplatin 的高是 10 褶层。1 并且没有搬运人蛋白质的帮助, 1-Ga 可能顺利越过肿瘤房间膜过去,并且在肿瘤的细胞质主要局部性房间。在太平洋夏季时间治疗以后,增加的细胞内部的反应的氧种类(ROS ) 水平和 mitochondrial 膜潜力显著地减少了,它将最后导致肿瘤房间的 apoptosis。Fan Cheng Liting Huang Huahua Wang Yunjun Liu Jaipal Kandhadi Hui Wang Liangnian Ji Haiyang Liu 2017Chinese Journal of Chemistry2017,35,1:1
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