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| 1 | ;he regulation of TGF-β/SMAD signaling by protein deubiquitination显示文摘 | Juan Zhang Xiaofei Zhang Feng Xie Zhengkui Zhang Hans van Dam Long Zhang Fangfang Zhou | 2014 | Protein & Cell2014，5，7： | 27 |
| 2 | Consensus on the application of negative pressure wound therapy of diabetic foot wounds显示文摘Because China is becoming an aging society,the incidence of diabetes and diabetic foot have been increasing.Diabetic foot has become one of the main health-related killers due to its high disability and mortality rates.Negative pressure wound therapy(NPWT)is one of the most effective techniques for the treatment of diabetic foot wounds and great progress,both in terms of research and its clinical application,has been made in the last 20 years of its development.However,due to the complex pathogenesis and management of diabetic foot,irregular application of NPWT often leads to complications,such as infection,bleeding and necrosis,that seriously affect its treatment outcomes.In 2020,under the leadership of Burns,Trauma and Tissue Repair Committee of the Cross-Straits Medicine Exchange Association,the writing group for‘Consensus on the application of negative pressure wound therapy of diabetic foot wounds’was established with the participation of scholars from the specialized areas of burns,endocrinology,vascular surgery,orthopedics and wound repair.Drawing on evidence-based practice suggested by the latest clinical research,this consensus proposes the best clinical practice guidelines for the application and prognostic evaluation of NPWT for diabetic foot.The consensus aims to support the formation of standardized treatment schemes that clinicians can refer to when treating cases of diabetic foot. | Shizhao Ji Xiaobin Liu Jie Huang Junmin Bao Zhaohong Chen Chunmao Han Daifeng Hao Jingsong Hong Dahai Hu Yufeng Jiang Shang Ju Hongye Li Zongyu Li Guangping Liang Yan Liu Gaoxing Luo Guozhong Lv Xingwu Ran Zhongmin Shi Juyu Tang Aiping Wang Guangyi Wang Jiangning Wang Xin Wang Bing Wen Jun Wu Hailin Xu Maojin Xu Xiaofei Ye Liangxi Yuan Yi Zhang Shichu Xiao Zhaofan Xia | 2021 | Burns & Trauma2021，9，1： | 17 |
| 3 | Facile synthesis of ultrathin metal-organic framework nanosheets for Lewis acid catalysis显示文摘Ultrathin metalorganic framework (MOF) nanosheets are attracting great interest in catalysis due to their unique and intriguing two-dime nsional (2D) features. Although many progresses have been achieved, it is still highly desirable to develop novel strategies for controllable synthesis of the well-defined ultrathin MOF nanosheets. Herein we report a polyvinylpyrrolidone (PVP)-assisted route to synthesize the ultrathin Ni-MOF nanosheets characteristic of 1.5 nm in thickness, in which PVP is reacted with 2-aminoterephthalic acid (H2BDC-NH2) via formation of C=N bon d, followed by coord inatio n with Ni2+ io ns to form the ultrathi n MOF n anosheets. Impressively, when used in the Kno eve nagel condensation reactions of propane dinitrile with different aldehydes, ultrathin Ni-MOF nanosheets display the significantly enhanced catalytic activity and good stability in respect with the bulk Ni-MOF, mainly owing to the exposed active sites as well as facile mass transfer and diffusion of substrates and products. | Xiaofei Zhang Lin Chang Zhongjie Yang Yanan Shi Chang Long Jianyu Han Binhao Zhang Xueying Qiu Guodong Li Zhiyong Tang | 2019 | Nano Research2019，12，2： | 11 |
| 4 | UBE20 negatively regulates TRAF6-mediated NF-kB activation by inhibiting TRAF6 polyubiquitination显示文摘 | Xiaofei Zhang Juan Zhang Long Zhang Hans van Dam Peter ten Dijke | 2013 | Cell Research2013，23，3： | 8 |
| 5 | Hepatitis B virus X protein represses miRNA-148a to enhance tumorigenesis显示文摘 | Xu Xiaojie Fan Zhongyi Kang Lei Han Juqiang Jiang Chengying Zheng Xiaofei Zhu Ziman Jiao Huabo Lin Jing Jiang Kai Ding Lihua Zhang Hao Cheng Long Fu Hanjiang Song Yi Jiang Ying Liu Jiahong Wang Rongfu Du Nan Ye Qinong | 2013 | Journal of Clinical Investigation2013，，2： | 7 |
| 6 | Catalytic conversion of lignocellulosic biomass into chemicals and fuels显示文摘In the search of alternative resources to make commodity chemicals and transportation fuels for a low carbon future,lignocellulosic biomass with over 180-billion-ton annual production rate has been identified as a promising feedstock.This review focuses on the state-of-the-art catalytic transformation of lignocellulosic biomass into value-added chemicals and fuels.Following a brief introduction on the structure,major resources and pretreatment methods of lignocellulosic biomass,the catalytic conversion of three main components,i.e.,cellulose,hemicellulose and lignin,into various compounds are comprehensively discussed.Either in separate steps or in one-pot,cellulose and hemicellulose are hydrolyzed into sugars and upgraded into oxygen-containing chemicals such as 5-HMF,furfural,polyols,and organic acids,or even nitrogen-containing chemicals such as amino acids.On the other hand,lignin is first depolymerized into phenols,catechols,guaiacols,aldehydes and ketones,and then further transformed into hydrocarbon fuels,bioplastic precursors and bioactive compounds.The review then introduces the transformations of whole biomass via catalytic gasification,catalytic pyrolysis,as well as emerging strategies.Finally,opportunities,challenges and prospective of woody biomass valorization are highlighted. | Weiping Deng Yunchao Feng Jie Fu Haiwei Guo Yong Guo Buxing Han Zhicheng Jiang Lingzhao Kong Changzhi Li Haichao Liu Phuc T.T.Nguyen Puning Ren Feng Wang Shuai Wang Yanqin Wang Ye Wang Sie Shing Wong Kai Yan Ning Yan Xiaofei Yang Yuanbao Zhang Zhanrong Zhang Xianhai Zeng Hui Zhou | 2023 | Green Energy & Environment2023，8，1： | 6 |
| 7 | SDS-modified Nanoporous Silver as an Efficient Electrocatalyst for Selectively Converting CO2 to CO in Aqueous Solution显示文摘Selectively electrochemical conversion of CO2 into organic fuel using renewable electricity is one of the most sought-after processes.In this paper,we report the electrochemical reduction of CO2(CO2RR)on the nanoporous Ag electrodes made of compacted Ag nanoparticles(AgNPs),which were prepared by one-step reduction in the water phase with or without the surfactant sodium dodecyl sulfate(SDS).The scanning electron microscope(SEM)characterizations show that the compacted Ag electrodes have the nanoporous morphology formed by stacking AgNPs.Compared with the nanoporous Ag electrode without SDS modification(C-AgNPs),the SDS-modified AgNPs electrode(C-AgNPs-SDS)is highly effective in improving selective CO production in a wide range of potentials(-0.69 V--1.19 V,vs.RHE),with a Faradaic efficiency of 92.2% and a current density of -8.23 mA·cm^-2 for CO production at -0.79 V(vs.RHE).C-AgNPs-SDS is also catalytically stable with only less than 7% deactivation after 8 h of continuous electrolysis. | Lei Shi Yuning Zhang Xiaofei Han Dongfang Niu Jinlong Sun Jenny Y.Yang Shuozhen Hu Xinsheng Zhang | 2019 | Chinese Journal of Chemistry2019，37，4： | 5 |
| 8 | Light-absorbing impurities on Keqikaer Glacier in western Tien Shan: concentrations and potential impact on albedo reduction显示文摘Light-absorbing impurities on glaciers are important factors that influence glacial surface albedo and accelerate glacier melt. In this study, the quantity of light-absorbing impurities on Keqikaer Glacier in western Tien Shan, Central Asia, was measured. We found that the average concentrations of black carbon was 2,180 ng/g, with a range from 250 ng/g to more than 10,000 ng/g. The average concentrations of organic carbon and mineral dust were 1,738 ng/g and 194 μg/g, respectively. Based on simulations performed with the Snow Ice Aerosol Radiative model simulations, black carbon and dust are responsible for approximately 64% and 9%, respectively, of the albedo reduction, and are associated with instantaneous radiative forcing of 323.18 W/m2(ranging from 142.16 to 619.25 W/m2) and 24.05 W/m2(ranging from 0.15 to69.77 W/m2), respectively. For different scenarios, the albedo and radiative forcing effect of black carbon is considerably greater than that of dust. The estimated radiative forcing at Keqikaer Glacier is higher than most similar values estimated by previous studies on the Tibetan Plateau, perhaps as a result of black carbon enrichment by melt scavenging. Light-absorbing impurities deposited on Keqikaer Glacier appear to mainly originate from central Asia, Siberia, western China(including the Taklimakan Desert) and parts of South Asia in summer, and from the Middle East and Central Asia in winter.A footprint analysis indicates that a large fraction(>60%) of the black carbon contributions on Keqikaer Glacier comes from anthropogenic sources. These results provide a scientific basis for regional mitigation efforts to reduce black carbon. | YuLan Zhang ShiChang Kang Min Xu Michael Sprenger TanGuang Gao ZhiYuan Cong ChaoLiu Li JunMing Guo ZhiQiang Xu Yang Li Gang Li XiaoFei Li YaJun Liu HaiDong Han | 2017 | Research in Cold and Arid Regions2017，9，2： | 4 |
| 9 | MiR-205 inhibits the invasion and migration of esophageal squamous cell carcinoma by modulating SMAD1 expression显示文摘Esophageal squamous cell carcinoma(ESCC)is one of the most lethal cancers worldwide.In this study,we aimed to investigate the underlying mechanisms of metastasis inhibition by miR-205 in ESCC.In microRNA(miRNA)array and quantitative RT-PCR analyses,we found that the expression level of miR-205 was significantly lower in patients with lymph node metastasis compared with that in patients without lymph node metastasis.After transfection of miR-205 mimics or inhibitors into ESCC cell lines,a significant negative correlation was observed between the expression level of miR-205 and Smad1.In luciferase reporter assays,we revealed that miR-205 inhibited the expression of SMAD1 by targeting the 30untranslated region(30-UTR)of SMAD1 mRNA in ESCC cells.Furthermore,our results showed that miR-205 suppressed the invasion and migration of ESCC cells,whereas Smad1 increased their invasion and migration.Taken together,our study demonstrates that miR-205 functions as a suppressor of tumor metastasis by regulating SMAD1expression through targeting the 30-UTR of SMAD1 mRNAin ESCC.Therefore,miR-205 may be a potential therapeutic target for miRNA-based therapy of ESCC. | Baoyu Liang Yan Wu Xu Han Xiaofei Zheng Qimin Zhan Tong Tong | 2014 | Chinese Science Bulletin2014，59，19： | 4 |
| 10 | Stability,Thermal Conductivity and Photothermal Conversion Performance of Water-Based ZnO Nanofluids显示文摘Water-based ZnO nanofluids were prepared via the two-step method,and the influences of dispersant type and mass fraction on the stability and particle size distribution of the nanofluids were investigated.The spectral transmittances of the nanofluids were obtained by a UV-Vis-NIR spectrophotometer.Thermal conductivities of the nanofluids with various mass fractions were measured at different temperatures and a fitted nonlinear correlated equation was established for low-concentration application and compared with existing models.The photothermal conversion performance of the nanofluids was evaluated by theoretical and experimental methods at three optical depths.The results showed that,CTAB as the dispersant provides better physical stability of water-based ZnO nanofluids than SDBS or GA does.Effect of the temperature on the nanofluid thermal conductivity is remarkable with the increase of nanoparticle mass fraction,especially in the range 55°C to 75°C.The maximum thermal conductivity of the studied nanofluids is 0.9488 W/(m·℃)at 75°C,43.61%higher than that of water.The minimum thermal conductivity of the studied nanofluids is 0.6376 W/(m·℃)at 25°C,5.16%higher than that of water.The photothermal conversion performance of the nanofluids is quite good with a maximum average absorption efficiency of 0.47,135%higher than that of water(η=0.2),and the maximum SAR is 527.5 W/g. | HAN Xiaofei LU Liwei YAN Suying YANG Xiaohong TIAN Rui ZHAO Xiaoyan | 2021 | Journal of Thermal Science2021，30，5： | 3 |
| 11 | Genotypic variation in spatiotemporal distribution of canopy light interception in relation to yield formation in cotton显示文摘Background: Within-canopy interception of photosynthetically active radiation(PAR) impacts yield and other agronomic traits in cotton(Gossypium hirsutum L.). Field experiments were conducted to investigate the influence of 6 cotton varieties(they belong to 3 different plant types) on yield, yield distribution, light interception(LI), LI distribution and the relationship between yield formation and LI in Anyang, Henan, in 2014 and 2015.Result: The results showed that cotton cultivars with long branches(loose-type) intercepted more LI than did cultivars with short branches(compact-type), due to increased LI in the middle and upper canopy. Although loose-type varieties had greater LI, they did not yield significantly higher than compact-type varieties, due to decreased harvest index. Therefore, improving the harvest index by adjusting the source-to-sink relationship may further increase cotton yield for loose-type cotton. In addition, there was a positive relationship between reproductive organ biomass accumulation and canopy-accumulated LI, indicating that enhancing LI is important for yield improvement for each cultivar. Furthermore, yield distribution within the canopy was significantly linearly related to vertical LI distribution.Conclusion: Therefore, optimizing canopy structure of different plant type and subsequently optimizing LI distribution within the cotton canopy can effectively enhance the yield. | XING Fangfang HAN Yingchun FENG Lu ZHI Xiaoyu WANG Guoping YANG Beifang FAN Zhengyi LEI Yaping DU Wenli WANG Zhanbiao XIONG Shiwu LI Xiaofei Ll Yabing | 2018 | Journal of Cotton Research2018，1，3： | 3 |
| 12 | Low intensity near-infrared light promotes bone regeneration via circadian clock protein cryptochrome 1显示文摘Bone regeneration remains a great clinical challenge. Low intensity near-infrared(NIR) light showed strong potential to promote tissue regeneration, offering a promising strategy for bone defect regeneration. However, the effect and underlying mechanism of NIR on bone regeneration remain unclear. We demonstrated that bone regeneration in the rat skull defect model was significantly accelerated with low-intensity NIR stimulation. In vitro studies showed that NIR stimulation could promote the osteoblast differentiation in bone mesenchymal stem cells(BMSCs) and MC3T3-E1 cells, which was associated with increased ubiquitination of the core circadian clock protein Cryptochrome 1(CRY1) in the nucleus. We found that the reduction of CRY1 induced by NIR light activated the bone morphogenetic protein(BMP) signaling pathways, promoting SMAD1/5/9 phosphorylation and increasing the expression levels of Runx2 and Osterix. NIR light treatment may act through sodium voltage-gated channel Scn4a, which may be a potential responder of NIR light to accelerate bone regeneration. Together, these findings suggest that low-intensity NIR light may promote in situ bone regeneration in a CRY1-dependent manner, providing a novel, efficient and non-invasive strategy to promote bone regeneration for clinical bone defects. | Jinfeng Peng Jiajia Zhao Qingming Tang Jinyu Wang Wencheng Song Xiaofeng Lu Xiaofei Huang Guangjin Chen Wenhao Zheng Luoying Zhang Yunyun Han Chunze Yan Qian Wan Lili Chen | 2022 | International Journal of Oral Science2022，14，4： | 2 |
| 13 | Metaxin deficiency alters mitochondrial membrane permeability and leads to resistance to TNF-induced cell killing显示文摘The correspondence would like to state that Paul Bornstein and Lucas Armstrong were not given an opportunity to review the manuscript of this paper. | Koh Ono Xiaofei Wang Sung Ouk Kim Lucas CArmstrong Paul Bornstein Jiahuai Han | 2010 | Protein & Cell2010，1，12： | 2 |
| 14 | Ultrafast multi-target control of tightly focused light fields显示文摘The control of ultrafast optical field is of great interest in developing ultrafast optics as well as the investigation on vari-ous light-matter interactions with ultrashort pulses.However,conventional spatial encoding approaches have only lim-ited steerable targets usually neglecting the temporal effect,thus hindering their broad applications.Here we present a new concept for realizing ultrafast modulation of multi-target focal fields based on the facile combination of time-depend-ent vectorial diffraction theory with fast Fourier transform.This is achieved by focusing femtosecond pulsed light carrying vectorial-vortex by a single objective lens under tight focusing condition.It is uncovered that the ultrafast temporal de-gree of freedom within a configurable temporal duration(~400 fs)plays a pivotal role in determining the rich and exotic features of the focused optical field at one time,namely,bright-dark alternation,periodic rotation,and longitudinal/trans-verse polarization conversion.The underlying control mechanisms have been unveiled.Besides being of academic in-terest in diverse ultrafast spectral regimes,these peculiar behaviors of the space-time evolutionary beams may underpin prolific ultrafast-related applications such as multifunctional integrated optical chip,high-efficiency laser trapping,micro-structure rotation,super-resolution optical microscopy,precise optical measurement,and liveness tracking. | Yanxiang Zhang Xiaofei Liu Han Lin Dan Wang Ensi Cao Shaoding Liu Zhongquan Nie Baohua Jia | 2022 | Opto-Electronic Advances2022，5，3： | 2 |
| 15 | Contrasting effects of nitrogen addition on litter decomposition in forests and grasslands in China显示文摘Nitrogen(N)addition has profound impacts on litter-mediated nutrient cycling.Numerous studies have reported different effects of N addition on litter decomposition,exhibiting positive,negative,or neutral effects.Previous meta-analysis of litter decomposition under N addition was mainly based on a small number of samples to allow comparisons among ecosystem types.This study presents the results of a meta-analysis incorporating data from 53 published studies(including 617 observations)across forests,grasslands,wetlands,and croplands in China,to investigate how environmental and experimental factors impact the effects of N addition on litter decomposition.Averaged across all of the studies,N addition significantly slows litter decomposition by 7.02%.Considering ecosystem types,N addition significantly accelerates litter decomposition by 3.70%and 11.22%in grasslands and wetlands,respectively,clearly inhibits litter decomposition by 14.53%in forests,and has no significant effects on litter decomposition in croplands.Regarding the accelerated litter decomposition rate in grasslands due to N addition,litter decomposition rate increases slightly with increasing rates of N addition.However,N addition slows litter decomposition in forests,but litter decomposition is at a significantly increasing rate with increasing amounts of N addition.The responses of litter decomposition to N addition are also influenced by the forms of N addition,experiential duration of N addition,humidity index,litter quality,and soil pH.In summary,N addition alters litter decomposition rate,but the direction and magnitude of the response are affected by the forms of N addition,the rate of N addition,ambient N deposition,experimental duration,and climate factors.Our study highlights the contrasting effects of N addition on litter decomposition in forests and grasslands.This finding could be used in biogeochemical models to better evaluate ecosystem carbon cycling under increasing N deposition due to the differential responses of litter decomposition to N addition rates and ecosystem types. | SU Yuan MA Xiaofei GONG Yanming LI Kaihui HAN Wenxuan LIU Xuejun | 2021 | Journal of Arid Land2021，13，7： | 2 |
| 16 | MTERF3 contributes to MPP+-induced mitochondrial dysfunction in SH-SY5Y cells显示文摘Parkinson’s disease(PD)is a neurodegenerative disorder causing severe social and economic burdens.The origin of PD has been usually attributed to mitochondrial dysfunction.To this end,mitochondrial transcription regulators become attractive subjects for understanding PD pathogenesis.Previously,we found that the expression of mitochondrial transcription termination factor 3(MTERF3)was reduced in MPP+-induced mice model of PD.In the present study,we probe the function of MTERF3 and its role in MPP+-induced cellular model of PD.Initially,we observe that MTERF3 expression is also reduced in MPP+-induced cellular model of PD,which can be mainly attributed to the increase of MTERF3 degradation.Next,we examine the effect of MTERF3 knockdown and overexpression on the replication,transcription,and translation of mitochondrial DNA(mtDNA).We show that knockdown and overexpression of MTERF3 have opposite effects on mtDNA transcript level but similar effects on mtDNA expression level,in line with MTERF3’s dual roles in mtDNA transcription and translation.In addition,we examine the effect of MTERF3 knockdown and overexpression on mitochondrial function with and without MPP+treatment,and find that MTERF3 seems to play a generally protective role in MPP+-induced mitochondrial dysfunction.Together,this work suggests a regulatory role of MTERF3 in MPP+-induced cellular model of PD and may provide clues in designing novel therapeutics against PD. | Shun Zhu Nan Xu Yanyan Han Xiaofei Ye Ling Yang Ji Zuo Wen Liu | 2022 | Acta Biochimica et Biophysica Sinica2022，54，8： | 2 |
| 17 | Implementation of the Earth-based planetary radio occultation inversion technique显示文摘The planetary radio occultation technique is one of the earliest suggested and achieved methods to detect the planetary atmosphere,and has been conducted by almost every deep space planetary probe.The principles,modules,inversion results and primary analysis of the SHAO Planetary Occultation observation Processing system(SPOPs) are presented in this paper.Utilizing open-loop and closed-loop Doppler residual data of the Mars Express radio occultation experiment provided by ESA PSA and NASA PDS,the temperature,pressure,molecular number density profiles of Martian atmosphere and electron density profiles of the ionosphere are successfully retrieved,and the results are validated by the released radio science level 04 products of the ESA MaRS group.This system can also process the atmosphere radio occultation observations of other planets and theirs natural satellites.The implementation of the planetary radio occultation technique is of significance to China's YH-1 Mars exploration project,as well as for future planetary exploration missions from China. | ZHANG SuJun PING JinSong HAN TingTing MAO XiaoFei HONG ZhenJie | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，7： | 2 |
| 18 | Document Clustering Using Locality Preserving Indexing显示文摘 | Cai Deng He Xiaofei Han Jiawei | 2005 | Knowledge and Data Engineering2005，17，12： | 1 |
| 19 | Hyaluronic acid-based dual-responsive nanomicelles mediated mutually synergistic photothermal and molecular targeting therapies显示文摘Precise clinical treatment of triple-negative breast cancer(TNBC)is an obstacle in clinic.Nanotechnology-assisted photothermal therapy(PTT)is a superior treatment modality for TNBC in terms of precision.However,thermoresistance arising from PTT and insufficient drug release from nanocarriers decrease the efficacy of PTT.AT13387 is a novel HSP90 inhibitor that can weaken thermoresistance and undergoing clinic II phase study,showing satisfactory antitumour activity through molecularly targeted therapy(MTT).Whereas,it has poor solubility.Hence hyaluronic acid and stearic acid were connected by hydrazone bonds and disulfide bonds,forming an amphipathic copolymer that could self-assembled into nanomicelles,followed by encapsulating Cypate and AT13387.These nanomicelles exhibited great features,including achieving mutually synergistic PTT/MTT for overcoming thermoresistance and promoting translocation of drugs,increasing the solubility of Cypate and AT13387,showing a pH/redox dual response that contributes to drug release,and having the ability of active targeting.Thus,the nanomicelles developed in this study may be a promising strategy for the precise treatment of TNBC. | Liangliang Cai Ronghua Ni Xiaofei Ma Rongrong Huang Zhiyuan Tang Jinqiu Xu Yong Han Yuehua Guo Zhifeng Gu | 2022 | Nano Research2022，15，7： | 1 |
| 20 | Graph Regularized Non-negative Matrix Factorization for Data Representation 显示文摘 | CAI Deng HE Xiaofei HAN Jiawei | 2011 | IEEE Trans Pattern Anal Maeh Intel2011，33，8： | 1 |
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