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| 1 | Prognostic factors for transarterial chemoembolization combined with sustained oxaliplatin-based hepatic arterial infusion chemotherapy of colorectal cancer liver metastasis显示文摘Objective: To investigate the prognostic factors in chemorefractory colorectal cancer liver metastasis(CRCLM)patients treated by transarterial chemoembolization(TACE) and sustained hepatic arterial infusion chemotherapy(HAIC).Methods: Between 2006 and 2015, 162 patients who underwent 763 TACE and HAIC in total were enrolled in this retrospective study, including 110 males and 52 females, with a median age of 60(range, 26–83) years.Prognostic factors were assessed with Log-rank test, Cox univariate and multivariate analyses.Results: The median survival time(MST) and median progression-free survival(PFS) of the 162 patients from first TACE/HAIC were 15.6 months and 5.5 months respectively. Normal serum carbohydrate antigen 19-9(CA19-9, <37 U/m L)(P<0.001) and carbohydrate antigen 72-4(CA72-4, <6.7 U/m L)(P=0.026), combination with other local treatment(liver radiotherapy or liver radiofrequency ablation)(P=0.034) and response to TACE/HAIC(P<0.001) were significant factors related to survival after TACE/HAIC in univariate analysis. A multivariate analysis revealed that normal serum CA19-9(P<0.001), response to TACE/HAIC(P<0.001) and combination with other local treatment(P=0.001) were independent factors among them.Conclusions: Our findings indicate that serum CA19-9 <37 U/m L and response to TACE/HAIC are significant prognostic indicators for this combined treatment, and treated with other local treatment could reach a considerable survival benefit for CRCLM. This could be useful for making decisions regarding the treatment of CRCLM. | Hangyu Zhang Jianhai Guo Song Gao Pengjun Zhang Hui Chen Xiaodong Wang Xiaoting Li Xu Zhu | 2017 | Chinese Journal of Cancer Research2017，29，1： | 12 |
| 2 | Abrogation of Hn RNP L enhances anti-PD-1 therapy efficacy via diminishing PD-L1 and promoting CD8^(+) T cell-mediated ferroptosis in castration-resistant prostate cancer显示文摘Owing to incurable castration-resistant prostate cancer(CRPC)ultimately developing after treating with androgen deprivation therapy(ADT),it is vital to devise new therapeutic strategies to treat CRPC.Treatments that target programmed cell death protein 1(PD-1)and programmed death ligand-1(PD-L1)have been approved for human cancers with clinical benefit.However,many patients,especially prostate cancer,fail to respond to anti-PD-1/PD-L1 treatment,so it is an urgent need to seek a support strategy for improving the traditional PD-1/PD-L1 targeting immunotherapy.In the present study,analyzing the data from our prostate cancer tissue microarray,we found that PD-L1 expression was positively correlated with the expression of heterogeneous nuclear ribonucleoprotein L(Hn RNP L).Hence,we further investigated the potential role of Hn RNP L on the PD-L1 expression,the sensitivity of cancer cells to T-cell killing and the synergistic effect with anti-PD-1 therapy in CRPC.Indeed,Hn RNP L knockdown effectively decreased PD-L1 expression and recovered the sensitivity of cancer cells to T-cell killing in vitro and in vivo,on the contrary,Hn RNP L overexpression led to the opposite effect in CRPC cells.In addition,consistent with the previous study,we revealed that ferroptosis played a critical role in T-cell-induced cancer cell death,and Hn RNP L promoted the cancer immune escape partly through targeting YY1/PD-L1 axis and inhibiting ferroptosis in CRPC cells.Furthermore,Hn RNP L knockdown enhanced antitumor immunity by recruiting infiltrating CD8^(+)T cells and synergized with anti-PD-1 therapy in CRPC tumors.This study provided biological evidence that Hn RNP L knockdown might be a novel therapeutic agent in PD-L1/PD-1 blockade strategy that enhanced anti-tumor immune response in CRPC. | Xumin Zhou Libin Zou Hangyu Liao Junqi Luo Taowei Yang Jun Wu Wenbin Chen Kaihui Wu Shengren Cen Daojun Lv Fangpeng Shu Yu Yang Chun Li Bingkun Li Xiangming Mao | 2022 | Acta Pharmaceutica Sinica B2022，12，2： | 4 |
| 3 | Pristine PN junction toward atomic layer devices显示文摘In semiconductor manufacturing,PN junction is formed by introducing dopants to activate neighboring electron and hole conductance.To avoid structural distortion and failure,it generally requires the foreign dopants localize in the designated micro-areas.This,however,is challenging due to an inevitable interdiffusion process.Here we report a brand-new junction architecture,called'layer PN junction',that might break through such limit and help redefine the semiconductor device architecture.Different from all existing semiconductors,we find that a variety of van der Waals materials are doping themselves from n-to p-type conductance with an increasing/decreasing layer-number.It means the capability of constructing homogeneous PN junctions in monolayers'dimension/precision,with record high rectification-ratio(>10^(5))and low cut-off current(<1 pA).More importantly,it spawns intriguing functionalities,like gate-switchable-rectification and noise-signal decoupled avalanching.Findings disclosed here might open up a path to develop novel nanodevice applications,where the geometrical size becomes the only critical factor in tuning charge-carrier distribution and thus functionality. | Hui Xia Man Luo Wenjing Wang Hailu Wang Tianxin Li Zhen Wang Hangyu Xu Yue Chen Yong Zhou Fang Wang Runzhang Xie Peng Wang Weida Hu Wei Lu | 2022 | Light(Science & Applications)2022，11，7： | 4 |
| 4 | Plasmacytoid dendritic cell deficiency in neonates enhances allergic airway inflammation via reduced production of IFN-α显示文摘Allergic asthma,a chronic inflammatory airway disease associated with type 2 cytokines,often originates in early life.Immune responses at an early age exhibit a Th2 cell bias,but the precise mechanisms remain elusive.Plasmacytoid dendritic cells(pDCs),which play a regulatory role in allergic asthma,were shown to be deficient in neonatal mice.We report here that this pDC deficiency renders neonatal mice more susceptible to severe allergic airway inflammation than adult mice in an OVA-induced experimental asthma model.Adoptive transfer of pDCs or administration of IFN-αto neonatal mice prevented the development of allergic inflammation in wild type but not in IFNAR1−/−mice.Similarly,adult mice developed more severe allergic inflammation when pDCs were depleted.The protective effects of pDCs were mediated by the pDC-/IFN-α-mediated negative regulation of the secretion of epithelial cell-derived CCL20,GM-CSF,and IL-33,which in turn impaired the recruitment of cDC2 and ILC2 cells to the airway.In asthmatic patients,the percentage of pDCs and the level of IFN-αwere lower in children than in adults.These results indicate that impairment of pDC-epithelial cell crosstalk in neonates is a susceptibility factor for the development of allergeninduced allergic airway inflammation. | Min Wu Liuchuang Gao Miao He Hangyu Liu Han Jiang Ketai Shi Runshi Shang Bing Liu Shan Gao Hebin Chen Feili Gong Erwin WGelfand Yafei Huang Junyan Han | 2020 | Cellular & Molecular Immunology2020，17，5： | 3 |
| 5 | Regulating the growth of lithium dendrite by coating an ultra-thin layer of gold on separator for improving the fast-charging ability of graphite anode显示文摘With the ever-growing application of lithium-ion batteries(LIBs), their fast-charging technology has attracted great interests of scientists. However, growth of lithium dendrites during fast charge of the bat teries with high energy density may pose great threats to the operation and cause serious safety issues Herein, we prepared a functional separator with an ultra-thin(20 nm) layer of Au nanoparticles deposited by evaporation coating method which could regulate growth direction and morphology of the lithium dendrites, owing to nearly zero overpotential of lithium meal nucleation on lithiated Au. Once the Li den drites are about to form on the graphite anode during fast charging(or lithiation), they plate predomi nantly on the Au deposited separator rather than on the graphite. Such selective deposition does no compromise the electrochemical performance of batteries under normal cycling. More importantly, i enables the better cycling stability of batteries at fast charge condition. The Li/Graphite cells with Au nanoparticles coated separator could cycle stably with a high areal capacity retention of 90.5% over 95 cycles at the current density of 0.72 m A cm^(-2). The functional separator provides an effective strategy to adjust lithium plating position at fast charge to ensure high safety of batteries without a compromise on the energy density of LIBs. | Shuaishuai Yan Xiaoxia Chen Pan Zhou Peican Wang Hangyu Zhou Weili Zhang Yingchun Xia Kai Liu | 2022 | Journal of Energy Chemistry2022，31，4： | 2 |
| 6 | Degradation of metronidazole by dielectric barrier discharge in an aqueous solution显示文摘Degradation of metronidazole (MNZ) which is a representative and stable antibiotic by dielectric barrier discharge (DBD) in an aqueous solution has been studied. Effects of initial MNZ concentration, solution pH and coexisting organics on the degradation were investigated. The results illustrated that increasing the input power and the discharge frequency can improve the removal of MNZ. At low initial concentration, the removal of MNZ can reach up to 99.1%. Acidic and neutral conditions are more favorable for MNZ removal than alkaline condition in the early stage of degradation. However, the difference in MNZ removal between those in acidic or neutral media and that in alkaline one could be neglected with prolonging of the treatment time. Therefore, this method can be applied to MNZ degradation with a wide pH range. Coexisting organic matter in water can attenuate the removal to some extent. This study could provide valuable references for the degradation of nitroimidazole antibiotics by DBD. | Zhipeng Yang Anxing Lai Hangyu Chen Youxiang Yan Ye Yang Weiwei Zhang Lei Wang | 2019 | Frontiers of Environmental Science & Engineering2019，13，3： | 1 |
| 7 | Identification and Analysis of Magnetic Structures on HL-2A显示文摘 | JI Xiaoquan YANG Qingwei FENG Beibing ZHOU Hangyu YUAN Baoshan CHEN Wei YANG Zhoujun | 2006 | Southwestern Institute of Physics Annual Report2006，，1： | 1 |
| 8 | New Exact Solutions of the CDGSK Equation Related to a Non-local Symmetry显示文摘A non-local symmetry of the Caudrey-Dodd-Gibbon-Sawada-Kotera(CDGSK)equation has been used for finding exact solution in two different ways.Firstly,using the standard prolongation approach,we obtain the finite Lie Bäcklund transformation and the single soliton solution.Secondly,combining some local symmetries and the nonlocal symmetry,we get the group invariant solution which is described by the Weierstrass elliptic function and is deduced to the so-called interacting soliton for a special parameter. | LOU Senyue RUAN Hangyu CHEN Weizhong WANG Zhenli CHEN Lili | 1994 | Chinese Physics Letters1994，11，10： | 1 |
| 9 | Diurnal evolution of the barrier layer and its local feedback in the central Taiwan Strait显示文摘Diurnal evolution of the barrier layer (BL) and its local feedback features in the central Taiwan Strait (119.2oE,24.3oN) during summertime monsoon are investigated using in situ moored observations conducted by the 'Yan-Ping 2' research vessel in late June 2005.During the initiation phase,for the non-solar radiation tends to be trapped in the upper mixed layer,whereas the solar radiation can penetrate deeply through the mixed layer approaching the thermocline,most heat is accumulated inside the BL inducing an inverse-thermal layer.Along with heat convergence inside the BL,thermal exchange increases between the BL and the overlaying mixed layer and finally,a prominently warming mixed layer is formed.Moreover,the BL is associated with a buoyancy frequency minimum with mild stability.Further analysis reveals that the BL's local feedbacks can be divided into two aspects,on one hand,the BL can generate dramatic changes in the local sensible and latent heat fluxes;on the other hand,the sub-halocline and the thermocline serve as two interfaces during the downward transmission of the wind stirring turbulent kinetic energy (TKE) and as a result,most TKE is retarded by the shallow halocline and being trapped above the upper mixed layer,while the residual pierced through the base of the mixed layer is likewise blocked by the thermocline. | PAN AiJun1,WAN XiaoFang,CHEN HangYu & GUO XiaoGang Ocean Dynamics Lab.,Third Institute of Oceanography State Oceanic Administration (TIOSOA),Xiamen 361005,China | 2010 | Science China Earth Sciences2010，53，2： | 1 |
| 10 | Similarity reductions of the KP equation by a direct method显示文摘 | Lou Senyue Ruan Hangyu Chen Defang | 1991 | J Phys A1991，24，： | 1 |
| 11 | Targeting N-methyl-D-aspartate receptors for treatment of neuropathic pain显示文摘 | ZHOU Hangyu CHEN Senrui PAN Hanli | 2011 | Expert Rev Clin Pharmacol2011，4，3： | 1 |
| 12 | Co‑packaged optics(CPO):status,challenges,and solutions显示文摘Due to the rise of 5G,IoT,AI,and high-performance computing applications,datacenter trafc has grown at a compound annual growth rate of nearly 30%.Furthermore,nearly three-fourths of the datacenter trafc resides within datacenters.The conventional pluggable optics increases at a much slower rate than that of datacenter trafc.The gap between application requirements and the capability of conventional pluggable optics keeps increasing,a trend that is unsustainable.Copackaged optics(CPO)is a disruptive approach to increasing the interconnecting bandwidth density and energy efciency by dramatically shortening the electrical link length through advanced packaging and co-optimization of electronics and photonics.CPO is widely regarded as a promising solution for future datacenter interconnections,and silicon platform is the most promising platform for large-scale integration.Leading international companies(e.g.,Intel,Broadcom and IBM)have heavily investigated in CPO technology,an inter-disciplinary research feld that involves photonic devices,integrated circuits design,packaging,photonic device modeling,electronic-photonic co-simulation,applications,and standardization.This review aims to provide the readers a comprehensive overview of the state-of-the-art progress of CPO in silicon platform,identify the key challenges,and point out the potential solutions,hoping to encourage collaboration between diferent research felds to accelerate the development of CPO technology. | Min Tan Jiang Xu Siyang Liu Junbo Feng Hua Zhang Chaonan Yao Shixi Chen Hangyu Guo Gengshi Han Zhanhao Wen Bao Chen Yu He Xuqiang Zheng Da Ming Yaowen Tu Qiang Fu Nan Qi Dan Li Li Geng Song Wen Fenghe Yang Huimin He Fengman Liu Haiyun Xue Yuhang Wang Ciyuan Qiu Guangcan Mi Yanbo Li Tianhai Chang Mingche Lai Luo Zhang Qinfen Hao Mengyuan Qin | 2023 | Frontiers of Optoelectronics2023，16，1： | 1 |
| 13 | The study of exact solutions to the nonlinear schrodinger equations in optical fiber显示文摘 | Ruan Hangyu Chen Yixin | | 0，，06： | 1 |
| 14 | Commonalities and characteristics of aqueous extracts from three Uighur medicines were analyzed by using three-stage infrared spectroscopy combined with ultra-performance liquid chromatography-time of flight-mass spectra显示文摘OBJECTIVE: To establish a method to analyze the commonalities and characteristics of the aqueous extracts from three Uighur medicines.METHODS: In this study, a combination method of three-stage infrared spectroscopy and ultra-performance liquid chromatography-time of flight-mass spectra(UPLC-TOF-MS) method was used to analyze the commonalities and characteristics of the aqueous extracts from Hezi(Fructus Chebulae),Maohezi(Terminalia Belliricae Fructus) and Xiqingguo(Chebulae Fructus Immaturus).RESULTS: In Fourier transform-infrared spectroscopy spectra, all three samples showed the characteristic absorption peaks of tannins similarly. According to UPLC-TOF-MS data analysis, the difference of the position and intensity of the peaks at 1713-1707 cm^(-1) in the three samples were related to the difference in the relative content of tannin and pentacyclic triterpenoids. In second derivative infrared spectroscopy spectra, further analysis of the differences in the infrared spectra of the three samples was performed by increasing the apparent resolution. In combination with UPLC-TOF-MS data, some features infrared absorption peaks were assigned.The absorption peaks at 1032-1030 cm^(-1) assigned to the stretching vibration of C-O-C(ether bond)groups of tannins; 1164-1163, 1063-1062, 1009-1005, 904 cm^(-1) attributed to the stretching vibration of C-O(ether bond) and C-O-C groups of glycosidic compounds. 1385-1383 cm^(-1) attributed to the bending vibration of C-H(alkyl hydrogen) of methoxyl group of pentacyclic triterpenoids. Peak 835 cm^(-1) was assigned to the characteristic absorption peak of bending vibration of = C-H groups of pentacyclic triterpenoids. The two dimensional correlation infrared spectroscopy could further quickly distinguish three samples through the dynamic structural information of their chemical components and discrepancy of auto-peaks and cross-peaks intuitively in the range of 1720-419 cm^(-1).CONCLUSION: By comparing the intensity of the infrared characteristic absorption peaks, the main chemical components were assigned, which significantly enriched and perfected the data analysis of the infrared spectra of three Uighur Medicines. It provided a rationale for the identification of medicinal materials with complex and similar chemical components using the three-stage infrared spectroscopy and UPLC-TOF-MS. | Qu Tiange Zhu Yun Zhang Ke Huang Jian Wang Hangyu Gao Le Liang Xu Chen Long Wang Jinhui Pang Xiaobo Duan Xingwu | 2019 | Journal of Traditional Chinese Medicine2019，39，1： | 1 |
| 15 | Isoforsythiaside confers neuroprotection against Alzheimer's disease by attenuating ferroptosis and neuroinflammation in vivo and in vitro显示文摘Ferroptosis and neuroinflammation contribute to the development of Alzheimer's disease(AD). Isoforsythiaside(IFY)is a phenylethanoid glycoside isolated from the dried fruit of Forsythia suspensa(Thunb.)Vahl that has been confirmed to improve the memory and cognitive abilities of APP/PS1 mice in our previous study. The purpose of this study was to explore the anti-ferroptosis and anti-neuroinflammatory properties of IFY-mediated neuroprotection. In APP/PS1 mice, erastin-damaged HT22 cells, and LPS-exposed BV2 cells, the neuroprotective effects against ferroptosis and neuroinflammation were investigated using immunohistochemistry, label-free proteomics, western blot, ELISA, MTT, fluorescence, and TEM. IFY alleviated the expression levels of NO, IL-6, and IL-1β in LPS-exposed BV2 cells and improved the morphology of mitochondria in erastin-damaged HT22 cells. Additionally, IFY upregulated the expression levels of GPX4, FTH, FTL, p-GSK-3β, Nrf2, and NQO1, and downregulated the expression of TFR1, DMT1, p-Fyn, GFAP, p-IKKα+β, p-IκBα, p-NF-κB, and pro-inflammatory factors in the brains of APP/PS1 mice and erastin-damaged HT22 cells. In conclusion, IFY inhibits ferroptosis and neuroinflammation in erastin-damaged HT22 cells and APP/PS1 mice, at least partially by regulating the activation of Nrf2 and NF-κB signaling. IFY may prevent ferroptosis and neuroinflammation in AD and provide a new treatment strategy for AD. | Chunyue Wang Hongbo Jiang Honghan Liu Shanshan Chen Hangyu Guo Shuoshuo Ma Weiwei Han Yu Li Di Wang | 2023 | Food Science and Human Wellness2023，12，5： | 0 |
| 16 | Strategies for high-performance perovskite solar cells from materials, film engineering to carrier dynamics and photon management显示文摘In recent years,halide perovskite solar cells(HPSCs)have attracted a great atten-tion due to their superior photoelectric performance and the low-cost of processing their quality films.In order to commercialize HPSCs,the researchers are focusing on developing high-performance HPSCs.Many strategies have been reported to increase the power conversion efficiency and the long-term stability of HPSCs over the past decade.Herein,we review the latest efforts and the chemical-physical principles for preparing high-efficiency and long-term stability HPSCs in particu-lar,concentrating on the perovskite materials,technologies for perovskite films,charge transport materials and ferroelectric effect to reduce the carrier loss,and photon management via plasmonic and upconversion effects.Finally,the key issues for future researches of HPSCs are also discussed with regard to the require-ments in practical application. | Huilin Li Chong Chen Hangyu Hu Yu Li Zhitao Shen Fumin Li Ying Liu Rong Liu Junwei Chen Chao Dong Sally Mabrouk Raja Sekhar Bobba Abiral Baniya Mingtai Wang Quinn Qiao | 2022 | InfoMat2022，4，7： | 0 |
| 17 | Estimate of contribution of near-inertial waves to the velocity shear in the Bay of Bengal based on mooring observations from2013 to 2014显示文摘Near-inertial motions contribute most of the velocity shear in the upper ocean.In the Bay of Bengal(BoB),the annual-mean energy flux from the wind to near-inertial motions in the mixed layer in 2013 is dominated by tropical cyclone(TC)processes.However,due to the lack of long-term observations of velocity profiles,our knowledge about interior near-inertial waves(NIWs)as well as their shear features is limited.In this study,we quantified the contribution of NIWs to shear by integrating the wavenumber-frequency spectra estimated from velocity profiles in the upper layers(40-440 m)of the southern Bo B from April 2013 to May 2014.It is shown that the annual-mean proportion of near-inertial shear out of the total is approximately 50%,and the high contribution is mainly due to the enhancement of the TC processes during which the near-inertial shear accounts for nearly 80%of the total.In the steady monsoon seasons,the near-inertial shear is dominant to or at least comparable with the subinertial shear.The contribution of NIWs to the total shear is lower during the summer monsoon than during the winter monsoon owing to more active mesoscale eddies and higher subinertial shear during the summer monsoon.The Doppler shifting of the M_(2)internal tide has little effect on the main results since the proportion of shear from the tidal motions is much lower than that from the near-inertial and subinertial motions. | Shanwu Zhang Yun Qiu Hangyu Chen Junqiang Shen Junpeng Zhang Jing Cha Fuwen Qiu Chunsheng Jing | 2021 | Acta Oceanologica Sinica2021，40，11： | 0 |
| 18 | Effects of landscape fragmentation of plantation forests on carbon storage in the Loess Plateau,China显示文摘Tree plantation and forest restoration are the major strategies for enhancing terrestrial carbon sequestration and mitigating climate change.The Grain for Green Project in China has positively impacted global carbon sequestration and the trend towards fragmentation of plantation forests.Limited studies have been conducted on changes in plantation biomass and stand structure caused by fragmentation,and the effect of fragmentation on the carbon storage of plantation forests remains unclear.This study evaluated the differences between carbon storage and stand structure in black locust forests in fragmented and continuous landscape in the Ansai District,China and discussed the effects of ecological significance of four landscape indices on carbon storage and tree density.We used structural equation modelling to explore the direct and indirect effects of fragmentation,edge,abiotic factors,and stand structure on above-ground carbon storage.Diameter at breast height(DBH)in fragmented forests was 53.3%thicker,tree density was 40.9%lower,and carbon storage was 49.8%higher than those in continuous forests;for all given DBH>10 cm,the trees in fragmented forests were shorter than those in continuous forests.The patch area had a negative impact on carbon storage,i.e.,the higher the degree of fragmentation,the lower the density of the tree;and fragmentation and distance to edge(DTE)directly increased canopy coverage.However,canopy coverage directly decreased carbon storage,and fragmentation directly increased carbon storage and tree density.In non-commercial forests,fragmentation reduces the carbon storage potential of plantation,and the influence of patch area,edge,and patchy connection on plantation should be considered when follow-up trees are planted and for the plantation management.Thus,expanding the area of plantation patches,repairing the edges of complex-shaped patches,enhancing the connectivity of similar patches,and applying nutrients to plantation forests at regular intervals are recommended in fragmented areas of the Loess Plateau. | LEI Hangyu DUAN Dantong CHEN Yi GUO Huifeng LI Jiangtao LI Xiang | 2024 | Journal of Arid Land2024，16，2： | 0 |
| 19 | Automatic extraction method of force chain information and its application in the flow photoelastic experiment of granular matter显示文摘The force chain is the core of the multi-scale analysis of granular matter.Accurately extracting the force chain information among particles is of great significance to the study of particle mechanics and geological hazards caused by particle flow.However,in the photoelastic experiment,the precise identification of the branching points of force chains has not been effectively realized.Therefore,this study proposes an automatic extraction method of force chain key information.First,based on the Hough transform and the Euclidean distance,a particle geometric information identification model is established and geometric information such as particle circle center coordinates,radius,contact point location,and contact angle is extracted.Then,a particle contact force information identification model is established following the color gradient mean square method.The model realizes the rapid calibration and extraction of a large number of particle media contact force information.Next,combined with the force chain composition criterion and its quasilinear feature,an automatic extraction method of force chain information is established,which solves the problem of the accurate identification of the force chain branch points.Finally,in the photoelastic experiment of ore drawing from a single drawpoint,the automatic extraction method of force chain information is verified.The results show that the macroscopic distribution of force chains during ore drawing from a single drawpoint is left–right symmetrical.Strong force chains are mostly located on the two sides of the model but in small numbers and they mainly develop vertically.Additionally,the ends are mostly in a combination of Y and inverted Y shapes,while the middle is mostly quasilinear.Weak force chains are abundant and mostly distributed in the middle of the model,and develop in different directions.The proposed extraction method accurately extracts the force chain network from the photoelastic experiment images and dynamically characterizes the force chains of granular matter,which has significant advantages in particle geometry information extraction,force chain branch point discrimination,force chain retrieval,and force chain distribution and its azimuthal characterization.The results provide a scientific basis for studying the macroscopic and microscopic mechanical parameters of granular matter. | Qingfa Chen Enlin Long Wenjing Niu Jun Liu Wenyu Fan Hangyu Li | 2023 | Particuology2023，，12： | 0 |
| 20 | Intra-seasonal variability of the abyssal currents in COMRA's contract area in the Clarion-Clipperton Zone显示文摘In this paper,the intra-seasonal variability of the abyssal currents in the China Ocean Mineral Resources Association(COMRA)polymetallic nodule contact area,located in the western part of the Clarion and Clipperton Fraction Zone in the tropical East Pacific,is investigated using direct observations from subsurface mooring instruments as well as sea-surface height data and reanalysis products.Mooring observations were conducted from September 13,2017 to August 15,2018 in the COMRA contact area(10°N,154°W).The results were as follows:(1)At depths below 200 m,the kinetic energy of intra-seasonal variability(20-100 d)accounts for more than 40%of the overall low-frequency variability,while the ratio reaches more than 50%below 2000 m.(2)At depths below 200 m,currents show a synchronous oscillation with a characteristic time scale of 30 d,lasting from October to the following January;the energy of the 30-d oscillation increases with depth until the layer of approximately 4616 m,and the maximum velocity is approximately 10 cm/s.(3)The 30-d oscillation of deep currents is correlated with the tropical instability waves in the upper ocean. | Fangfang Kuang Jing Cha Junpeng Zhang Aijun Pan Hangyu Chen Xiwu Zhou Chunsheng Jing Xiaogang Guo | 2022 | Acta Oceanologica Sinica2022，41，11： | 0 |
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