|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Geological Fluid Mapping in the Tongling Area:Implications for the Paleozoic Submarine Hydrothermal System in the Middle-Lower Yangtze Metallogenic Belt,East China显示文摘The Tongling area is one of the 7 ore-cluster areas in the Middle-Lower Yangtze metallogenic belt,East China,and has tectonically undergone a long-term geologic history from the late Paleozoic continental rifting,through the Middle Triassic continent-continent collision to the Jurassic-Cretaceous intracontinental tectono-magmatic activation.The Carboniferous sedimentary-exhalative processes in the area produced widespread massive sulfides with ages of 303-321 Ma,which partly formed massive pyrite-Cu deposits,but mostly provided significant sulfur and metals to the skarn Cu mineralization associated with the Yanshanian felsic intrusions. To understand the Carboniferous submarine hydrothermal system,an area of about 1046 km^2 was chosen to carry out the geological fluid mapping.Associated with massive sulfide formation,footwall sequences 948 m to 1146m thick,composed of the Lower Silurian-Upper Devonian sandstone,siltstone and thin-layered shale,were widely altered.This hydrothermal alteration is interpreted to reflect large- scale hydrothermal fluid flow associated with the late Paleozoic crustal rifting and subsidence.Three hydrothermal alteration types,i.e.,deep-level semiconformable silicification(S_1),fracture-controlled quartz-sericite-pyrite alteration(S_(2-3)),and upper-level sub-discordant quartz-sericite-chlorite alteration(D_3),were developed to form distinct zones in the mapped area.About 50-m thick semiconformable silicification zones are located at~1-km depth below massive sulfides and developed between an impermeable shale caprock(S_1)and the underlying Ordovician unaltered limestone. Comparisons with modern geothermal systems suggest that the alteration zones record a sub-seafloor aquifer with the most productive hydrothermal fluid flow.Fracture-controlled quartz-sericite-pyrite alteration formed transgressive zones,which downward crosscut the semiconformable alteration zones, and upwards grade into sub-discordant alteration zones that enveloped no economic stringer- stockwork zones beneath massive sulfides.This transgressive zone likely marks an upflow path of high- flux fluids from the hydrothermal aquifer.Lateral zonation of the sub-discordant alteration zones and their relationship to overlying massive sulfide lenses suggest lateral flows and diffusive discharging of the hydrothermal fluids in a permeable sandstone sequence.Three large-sized,14 middle-small massive sulfide deposits,and 40 massive sulfide sites have been mapped in detail.They show regional strata- bound characters and two major styles,i.e.,the layered sheet plus strata-bound stringer-style and the mound-style.Associated exhalite and chemical sedimentary rock suites include(1)anhydrite-barite,(2) jasper-chert,(3)Mg-rich mudstone-pyrite shale,(4)barite lens,(5)siderite-Fe-bearing dolomite,and (6)Mn-rich shale-mudstone,which usually comprise three sulfide-exhalite cyclic units in the area. The spatial distribution of these alteration zones(minerals)and associated massive sulfides and exhalites,and regional variation inδ^(34)S of hydrothermal pyrite and inδ^(18)O-δ^(34)C of hanging wall carbonates,suggest three WNW-extending domains of fluid flow,controlled by the basement faults and syn-depositional faults.Each fluid domain appears to have at least two upflow zones,with estimated even spacing of about 5-8 km in the mapped area.The repeated appearance of sulfide-sulfate or sulfide-carbonate rhythmic units in the area suggests episodically venting of fluids through the upflow conduits by breaking the overlying seals of the hydrothermal aquifer. | HOU Zengqian YANG Zhusen MENG Yifeng ZENG Pusheng LI Hongyang XU Wenyi | 2007 | Acta Geologica Sinica(English Edition)2007，81，5： | 8 |
| 2 | Serum DKK1 as a protein biomarker for the diagnosis of hepatocellular carcinoma: a large-scale, multicentre study显示文摘 | Qiujin Shen Jia Fan Xin-Rong Yang Yexiong Tan Weifeng Zhao Yang Xu Ning Wang Yongdong Niu Zheng Wu Jian Zhou Shuang-Jian Qiu Ying-Hong Shi Bin Yu Ning Tang Wei Chu Min Wang Jinhua Wu Zhigang Zhang Shengli Yang Jianren Gu Hongyang Wang Wenxin Qin | 2012 | Lancet Oncology2012，，8： | 4 |
| 3 | IUKF neural network modeling for FOG temperature drift显示文摘A novel neural network based on iterated unscented Kalman filter(IUKF) algorithm is established to model and compensate for the fiber optic gyro(FOG) bias drift caused by temperature. In the network, FOG temperature and its gradient are set as input and the FOG bias drift is set as the expected output. A2-5-1 network trained with IUKF algorithm is established. The IUKF algorithm is developed on the basis of the unscented Kalman filter(UKF). The weight and bias vectors of the hidden layer are set as the state of the UKF and its process and measurement equations are deduced according to the network architecture. To solve the unavoidable estimation deviation of the mean and covariance of the states in the UKF algorithm, iterative computation is introduced into the UKF after the measurement update. While the measurement noise R is extended into the state vectors before iteration in order to meet the statistic orthogonality of estimate and measurement noise. The IUKF algorithm can provide the optimized estimation for the neural network because of its state expansion and iteration. Temperature rise(-20-20 C) and drop(70-20 C)tests for FOG are carried out in an attemperator. The temperature drift model is built with neural network, and it is trained respectively with BP, UKF and IUKF algorithms. The results prove that the proposed model has higher precision compared with the backpropagation(BP) and UKF network models. | Feng Zha Jiangning Xu Jingshu Li Hongyang He | 2013 | Journal of Systems Engineering and Electronics2013，24，5： | 4 |
| 4 | Poly-PR in C9ORF72-Related Amyotrophic Lateral Sclerosis/Frontotemporal Dementia Causes Neurotoxicity by Clathrin-Dependent Endocytosis显示文摘GGGGCC repeat expansions in the C9 ORF72 gene are the most common cause of amyotrophic lateral sclerosis and frontotemporal dementia(c9 ALS/FTD). It has been reported that hexanucleotide repeat expansions in C9 ORF72 produce five dipeptide repeat(DPR) proteins by an unconventional repeat-associated non-ATG(RAN)translation. Within the five DPR proteins, poly-PR and poly-GR that contain arginine are more toxic than the other DPRs(poly-GA, poly-GP, and poly-PA). Here, we demonstrated that poly-PR peptides transferred into cells by endocytosis in a clathrin-dependent manner, leading to endoplasmic reticulum stress and cell death. In SH-SY5 Y cells and primary cortical neurons, poly-PR activated JUN amino-terminal kinase(JNK) and increased the levels of p53 and Bax. The uptake of poly-PR peptides by cells was significantly inhibited by knockdown of clathrin or by chlorpromazine, an inhibitor that blocks clathrin-mediated endocytosis. Inhibition of clathrin-dependent endocytosis by chlorpromazine significantly blocked the transfer of poly-PR peptides into cells, and attenuated poly-PRinduced JNK activation and cell death. Our data revealed that the uptake of poly-PR undergoes clathrin-dependentendocytosis and blockade of this process prevents the toxic effects of synthetic poly-PR peptides. | Rui Wang Xingyun Xu Zongbing Hao Shun Zhang Dan Wu Hongyang Sun Chenchen Mu Haigang Ren Guanghui Wang | 2019 | Neuroscience Bulletin2019，35，5： | 4 |
| 5 | Blue revolution for food security under carbon neutrality: A case from the water-saving and drought-resistance rice显示文摘The increasing concentration of greenhouse gases(GHGs)in Earth's atmosphere leads to global warming,which further causes a series of climate changes and does great harm to both human society and natural ecosystems.Agricultural GHG emissions,mainly in theform of methane(CH4)and nitrous oxide(N2O),areasignificantsourceofGHGs,accountingfor~14%total global GHGs(Zhang et al.,2022).One major source of agricultural GHGs is CH4 emissions from rice paddies,which is responsiblefor~10%-12%ofhuman-inducedCH4emissions(van Groenigen et al.,2013)and contributes~2.40%to the enhanced global warming effect(Zhang et al.,2022).The global warming potential of GHGs emissions from rice systems is roughly four times higher than either wheat or maize(Linquist et al.,2012). | Hui Xia Xianxian Zhang Yi Liu Junguo Bi Xiaosong Ma Anning Zhang Hongyan Liu Liang Chen Sheng Zhou Huan Gao Kai Xu Haibin Wei Guolan Liu Feiming Wang Hongyang Zhao Xingxing Luo Danping Hou Qiaojun Lou Fangjun Feng Liguo Zhou Shoujun Chen Ming Yan Tianfei Li Mingshou Li LeiWang Zaochang Liu Xinqiao Yu HanweiMei Lijun Luo | 2022 | Molecular Plant2022，15，9： | 3 |
| 6 | Metabolic Characterization of Hepatocellular Carcinoma Using Nontargeted Tissue Metabolomics显示文摘 | Qiang Huang Yexiong Tan Peiyuan Yin Guozhu Ye Peng Gao Xin Lu Hongyang Wang Guowang Xu | 2013 | Cancer Research2013，，16： | 2 |
| 7 | Evaluation on Fracture Toughness at Dynamic Loading for Welded Joint Based on the Local Approach显示文摘The changes in mechanical properties and fracture toughness by dynamic loading were investigated with experiments.The parameter R, which can reflect the effect of the loading rate and the temperature rising during the high loading rate, could be employed to describe the constituent relation for the typical structure steel and its weld metal. The dynamic loading effect on the stress/strain fields and the temperature variation in the vicinity of the crack tip was analyzed by the finite element method, the dynamic fracture behavior was evaluated based on the local approach. It has been found that the Weibull stress is an effective fracture parameter, independent of the temperature and the loading rate. | Hongyang JING, Lianyong XU, Lixing HUO and Yufeng ZHANGSchool of Materials Science and Engineering, Tianjin University, Tianjin 300072, China | 2004 | Journal of Materials Science & Technology2004，20，1： | 2 |
| 8 | Strongly coupled Te-SnS_(2)/MXene superstructure with self-autoadjustable function for fast and stable potassium ion storage显示文摘Potassium-ion batteries(PIBs)are a promising candidate for next-generation electric energy storage applications because of the abundance and low cost of potassium.However,the development of PIBs is limited by sluggish kinetics and huge volume expansion of anodes,leading to poor rate capability and cycling stability.Herein,an advanced superstructure anode,including Te-doped SnS_(2) nanosheets uniformly anchored on MXene surface(Te-SnS_(2)/MXene),is rationally designed for the first time to boost K^(+)storage performance.Featuring with strong interface interaction and self-autoadjustable interlayer spacings,the Te-SnS_(2)/MXene can efficiently accelerate electron/ion transfer,accommodate volume expansion,inhibit crack formation,and improve pseudocapacitive contribution during cycling.Thus,the novel Te-SnS_(2)/MXene anode delivers a high reversible capacity(343.2 mAh g^(-1) after 50 cycles at0.2 A g^(-1)),outstanding rate capability(186.4 mAh g^(-1) at 20 A g^(-1)),long cycle stability(165.8 mAh g^(-1)after 5000 cycles at 10 A g^(-1) with a low electrode swelling rate of only 15.4%),and reliable operation in flexible full battery.The present Te-SnS_(2)/MXene becomes among the best transition metal-based anode materials for PIBs reported to date. | Hongyang Sun Yelong Zhang Xiaodan Xu Jianwen Zhou Fan Yang Hao Li Hao Chen Yucheng Chen Zheng Liu Zhenping Qiu Da Wang Lipo Ma Jiawei Wang Qingguang Zeng Zhangquan Peng | 2021 | Journal of Energy Chemistry2021，30，10： | 2 |
| 9 | Fusion boundary evolution, precipitation behaviour, and interaction with dislocations in an Fe–22Cr–15Ni steel weldment during long-term creep显示文摘A tungsten inert gas welded joint between a novel heat-resistant austenitic steel and ERNiCrCoMo-1 weld metal was investigated before and after creep in this study. The evolution of the microstructures in the base and weld metals was discussed based on the electron back-scatter diffraction(EBSD) and transmission electron microscopy(TEM) analyses. The preferred orientations of the fusion boundary after creep revealed the influence of the applied stress on creep deformation mechanism. A cooperative nucleation process of M23C6 carbides in the base metal was proposed. The finely distributed Cu-rich phase was cut off by the dislocations during creep, leading to increased mean size and reduced amount of the nano-Cu phase. A modified triple-precipitate hardening model was constructed based on TEM observations of the interactions between the particles and the dislocations in the base metal after creep at 200 MPa. The evolution of a μ phase in the weld metal involved epitaxial growth and dissolving into the matrix. | Yu Zhang Hongyang Jing Lianyong Xu Yongdian Han Lei Zhao Xishan Xie Zhengxin Tang | 2019 | Progress in Natural Science:Materials International2019，29，1： | 2 |
| 10 | All in one theranostic nanoplatform enables efficient anti-tumor peptide I delivery for triple-modal imaging guided cancer therapy显示文摘Developing a reliable system to efficiently and safely deliver peptide drugs into tumor tissues still remains a great challenge since the instability of peptide drugs and low ability to traverse the cell membrane. Herein, we constructed a multifunctional nanoplatform based on porous europium/gadolinium (Eu/Gd)-doped NaLa(MoO4)2 nanoparticles (NLM NPs) to deliver antitumor peptide of B-cell lymphoma/leukemia-2-like protein 11 (BIM) for cancer therapy. The porous NLM NPs exhibited inherent photoluminescent, magnetic and X-ray absorbable properties, which enable them for triple-modal bioimaging, including fluorescence, magnetic resonance imaging (MRI) and computed tomography (CT). This triple-modal bioimaging can contribute to monitoring NLM NPs biodistribution and guiding therapy in vitro and in vivo. Furthermore, the NLM NPs showed negligible cytotoxicity in vitro and tissue toxicity in vivo. Importantly, NLM NPs could load the antitumor peptide of BIM and efficiently improve the resistance of peptide drugs to proteolysis. The BIM peptide was efficiently delivered into the tumor cells by NLM NPs, which can inhibit the growth and promote the apoptosis of cancer cells in vitro, significantly inhibit the tumor growth in vivo. Notably, NLM-BIM theranostic nanoplatform exhibits low systemic toxicity and fewer side effects in vivo. The NLM NPs can serve as a promising multifunctional peptide delivery nanoplatform for multi-modal bioimaging and cancer therapy. | Xiaoyan Qu Zhengqing Liu Bohan Ma Na Li Hongyang Zhao Tian Yang Yumeng Xue Xiaozhi Zhang Yongping Shao Ying Chang Jun Xu Bo Lei Yaping Du | 2019 | Nano Research2019，12，3： | 2 |
| 11 | Proper animal experimental designs for preclinical research of biomaterials for intervertebral disc regeneration显示文摘Low back pain is a vital musculoskeletal disease that impairs life quality,leads to disability and imposes heavy economic burden on the society,while it is greatly attributed to intervertebral disc degeneration(IDD).However,the existing treatments,such as medicines,chiropractic adjustments and surgery,cannot achieve ideal disc regeneration.Therefore,advanced bioactive therapies are implemented,including stem cells delivery,bioreagents administration,and implantation of biomaterials etc.Among these researches,few reported unsatisfying regenerative outcomes.However,these advanced therapies have barely achieved successful clinical translation.The main reason for the inconsistency between satisfying preclinical results and poor clinical translation may largely rely on the animal models that cannot actually simulate the human disc degeneration.The inappropriate animal model also leads to difficulties in comparing the efficacies among biomaterials in different reaches.Therefore,animal models that better simulate the clinical charateristics of human IDD should be acknowledged.In addition,in vivo regenerative outcomes should be carefully evaluated to obtain robust results.Nevertheless,many researches neglect certain critical characteristics,such as adhesive properties for biomaterials blocking annulus fibrosus defects and hyperalgesia that is closely related to the clinical manifestations,e.g,low back pain.Herein,in this review,we summarized the animal models established for IDD,and highlighted the proper models and parameters that may result in acknowledged IDD models.Then,we discussed the existing biomaterials for disc regeneration and the characteristics that should be considered for regenerating different parts of discs.Finally,well-established assays and parameters for in vivo disc regeneration are explored. | Yizhong Peng Xiangcheng Qing Hongyang Shu Shuo Tian Wenbo Yang Songfeng Chen Hui Lin Xiao Lv Lei Zhao Xi Chen Feifei Pu Donghua Huang Xu Cao Zengwu Shao | 2021 | Biomaterials Translational2021，2，2： | 2 |
| 12 | J-integral of interfacial crack between metal-base ceramic coating and steel显示文摘 | Xu Lianyong Jing Hongyang He Ying | | 0，，01： | 1 |
| 13 | Young's modulus and stress intensity factor determination of high velocity electric arc sprayed metal-based ceramic coatings显示文摘 | Xu Lianyong Jing Hongyang Huo Lixing | 2006 | Surf Coat Techn2006，201，6： | 1 |
| 14 | Growth and diode-pumped CW lasing of Nd:KLu(WO4)2显示文摘 | Zhang Jianxiu Wang Jiyang Zhang Huaijin Xu Fanghua Wang Zhengping Shao Zongshu Zhao Hongyang Wang Yuping | 2005 | Journal of Crystal Growth2005，284，： | 1 |
| 15 | A 2-step GPS carrier tracking loop for urban vehicle applications显示文摘Global positioning system(GPS) for vehicle applications in the urban area is challenged by low signal intensity. The carrier loop based on fast Fourier transform(FFT) can obtain a high signal to noise ratio(SNR) gain by increasing the observation time. However, this leads to a major problem that the acceleration cannot be ignored. The performance of the FFT-based loop will decline with the acceleration increasing. This paper discusses the effect of the dynamic on FFT first. Then a high performance carrier tracking loop for weak GPS L5 signals is proposed. It combines discrete chirp-Fourier transform(DCFT) and the phase fitting method to estimate Doppler frequency and Doppler rate simultaneously.First, a sequence of integration results is used to perform DCFT to estimate coarse Doppler frequency and Doppler rate. Second, the phase of the sequence is calculated and used to perform linear fitting. By the phase fitting method, the fine Doppler frequency and Doppler rate can be estimated. The computation cost is small because the integration results are used and the phase fitting method needs only coarse estimates of Doppler frequency and Doppler rate. Compared with FFT and DCFT, the precision of the phase fitting method is not limited by the resolution. Thus the proposed loop can get high precision and low carrier to noise ratio(C/N0) tracking threshold. Simulation results show this loop has a great improvement than conventional loops for urban weak-signal applications. | Hongyang Zhang Luping Xu Yue Jian Xiaochen Ma | 2017 | Journal of Systems Engineering and Electronics2017，28，5： | 1 |
| 16 | Improving performance of multi-infeed HVDC systems using grid dynamic segmentation technique based on fault current limiters显示文摘 | HUANG Hongyang XU Zheng LIN Xi | 2012 | IEEE Transactions on Power Systems2012，27，3： | 1 |
| 17 | Preparation and characterization of hollow glass microspheres/ZnO composites显示文摘 | Yongming Sui Haibin Yang Wuyou Fu Jing Xu Lianxia Chang Hongyang Zhu Qingjiang Yu Minghui Li Guangtian Zou | 2008 | Journal of Alloys and Compounds2008，，1： | 1 |
| 18 | Synthesis and characterization of hollow glass microspheres coated by SnO 2 nanoparticles显示文摘 | Jing Xu Haibin Yang Qingjiang Yu Lianxia Chang Xiaofen Pang Xiang Li Hongyang Zhu Minghui Li Guangtian Zou | 2006 | Materials Letters2006，，6： | 1 |
| 19 | 非洲猪瘟病毒pI215L蛋白介导非洲猪瘟病毒免疫逃逸新机制显示文摘非洲猪瘟(African swine fever,ASF)是由非洲猪瘟病毒(African swine fever virus,ASFV)感染家猪和野猪引起的一种急性、烈性传染病,高致病性病毒株感染的发病率和死亡率高达100%。ASF自2018年8月传入我国以来,对我国乃至世界养猪业造成了严重的经济损失。ASFV主要的靶细胞是巨噬细胞和单核细胞,其致病机制极其复杂。先天免疫是宿主防御病原感染的第一道防线,在抗病原感染过程中起着至关重要的作用。 | HUANG LI XU WEN-JIE LIU HONGYANG | 2022 | 中国预防兽医学报2022，44，2： | 1 |
| 20 | Improving perform- ance of mulfi-infeed HVDC systems using grid dynamic segmen- tation technique based on fault current limiters 显示文摘 | HUANG Hongyang XU Zheng LIN Xi | 2012 | IEEE Trans- actions on Power System2012，27，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员