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| 1 | Identification of coastal wetlands of international importance for waterbirds:a review of China Coastal Waterbird Surveys 2005–2013显示文摘Background:China's coastal wetlands belong to some of the most threatened ecosystems worldwide.The loss and degradation of these wetlands seriously threaten waterbirds that depend on wetlands.Methods:The China Coastal Waterbird Census was organized by volunteer birdwatchers in China's coastal region.Waterbirds were surveyed synchronously once every month at 14 sites,as well as irregularly at a further 18 sites,between September 2005 and December 2013.Results:A total of 75 species of waterbirds met the 1 % population level Ramsar listing criterion at least once at one site.The number of birds of the following species accounted for over 20 % of the total flyway populations at a single site:Mute Swan(Cygnus olor),Siberia Crane(Grus leucogeranus),Far Eastern Oystercatcher(Haematopus osculans),Bar-tailed Godwit(Limosa lapponica),Spotted Greenshank(Tringa guttifer),Great Knot(Calidris tenuirostris),Spoon-billed Sandpiper(Calidris pygmeus),Saunders' s Gull(Larus saundersi),Relict Gull(Larus relictus),Great Cormorant(Phalacrocorax carbo),Eurasian Spoonbill(Platalea leucorodia),Black-faced Spoonbill(Platalea minor) and Dalmatian Pelican(Pelecanus crispus).A total of 26 sites supported at least one species of which their number met the1 % criterion.Forty-two species met the 1 % criterion in the Yellow River Delta,Shandong;29 at the Cangzhou coast,Hebei and 26 species at the Lianyungang coast,Jiangsu.Conclusions:The results highlight the international importance of China's coastal wetlands for waterbirds.This study also demonstrates that participation of local birdwatchers in waterbird surveys results in data that are invaluable not only for understanding the current status of waterbirds in China's coastal regions but also for waterbird conservation and management. | Qingquan Bai Jianzhong Chen Zhihong Chen Guotai Dong Jiangtian Dong Wenxiao Dong Vivian Wing Kan Fu Yongxiang Han Gang Lu Jing Li Yang Liu Zhi Lin Derong Meng Jonathan Martinez Guanghui Ni Kai Shan Renjie Sun Suixing Tian Fengqin Wang Zhiwei Xu Yat-tung Yu Jin Yang Zhidong Yang Lin Zhang Ming Zhang Xiangwu Zeng | 2015 | Chinese Birds2015,,3: | 20 |
| 2 | Circulating tumor DNA 5-hydroxymethylcytosine as a novel diagnostic biomarker for esophageal cancer显示文摘 | Xin Tian Baofa Sun Chuanyuan Chen Chunchun Gao Ji Zhang XingYu Lu Linchen Wang Xiangnan Li Yurong Xing Ruijuan Liu Xiao Han Zheng Qi Xiaojian Zhang Chuan He Dali Han Yun-Gui Yang Quancheng Kan | 2018 | Cell Research2018,28,5: | 12 |
| 3 | Microstructure and Mechanical Properties of Al_2O_3/ZrO_2 Directionally Solidified Eutectic Ceramic Prepared by Laser 3D Printing显示文摘Directionally solidified eutectic ceramics such as(Al)_2O_3/ZrO_2 are promising structural materials for applications in harsh environment with an ultrahigh temperature. In this work, through adopting assistant heating laser 3D printing,(Al)_2O_3/ZrO_2eutectic samples were manufactured with suppressing the formation of cracks. The dependence of the average rod spacing(λav) on the scanning rate(V) follows a relation with λav V0.5= 1 μm1.5s–0.5. Typical eutectic microstructures, so-called complex regular, were analyzed with respect to its evolution with modulating the growth conditions. Formation mechanism of the solidification defect, shrinkage porosity, was discussed and the defect is found to be significantly suppressed by optimizing the solidification parameters. The maximum hardness and fracture toughness are measured to be 16.7 GPa and 4.5 MPa m1/2, respectively. The interplay between the propagation of cracks and the (Al)_2O_3/ZrO_2 interface is discussed. | Zhi Liu Kan Song Bo Gao Tian Tian Haiou Yang Xin Lin Weidong Huang | 2016 | Journal of Materials Science & Technology2016,32,4: | 12 |
| 4 | Transforming bacterial disease surveillance and investigation using whole-genome sequence to probe the trace显示文摘二十年后来过去了第一细菌的整个染色体的定序,它为微生物引起的染色体提供新机会。因而,可观的基因差异由细菌的染色体编码了,在在一样的种类之中,种类被揭示了。在最近的年里,染色体定序技术和生物信息学很快发展了,它导致了转变并且为在传染疾病流行病的解剖使用的细菌的染色体比较帮助了策略和方法论的应用程序。细菌的整个染色体的定序并且生物信息的计算允许 genotyping 在疾病控制满足流行病学的学习的要求。在这评论,我们构画出意义并且总结细菌的染色体在细菌的疾病控制和预防的上下文定序的角色。我们讨论细菌的染色体在爆发察觉,跟踪的来源,传播模式发现,和新流行克隆定序的应用程序鉴定。染色体在传染疾病监视网络定序并且数据分享的宽应用程序将更加支持爆发察觉和早警告阻止细菌的疾病的传播。 | Biao Kan Haijian Zhou Pengcheng Du Wen Zhang Xin Lu Tian Qin Jianguo Xu | 2018 | Frontiers of Medicine2018,12,1: | 11 |
| 5 | Hemodynamic changes of fractional flow reserve after double kissing crush and provisional stenting technique for true bifurcation lesions显示文摘 | YE Fei CHEN Shao-liang ZHANG Jun-jie ZHU Zhong-sheng KAN Jing TIAN Nai-liang LIN Song LIU Zhi-zhong YOU Wei XU Hai-mei XU Jing | 2012 | Chinese Medical Journal2012,,15: | 10 |
| 6 | Excessive gestational weight gain in early pregnancy and insufficient gestational weight gain in middle pregnancy increased risk of gestational diabetes mellitus显示文摘Background:Gestational weight gain(GWG)is associated with the risk of gestational diabetes mellitus(GDM).However,the effect of weight gain in different trimesters on the risk of GDM is unclear.This study aimed to evaluate the effect of GWG on GDM during different trimesters.Methods:A birth cohort study was conducted from 2017 to 2020 in Shenzhen,China.In total,51,205 participants were included comprising two models(early pregnancy model and middle pregnancy model).Gestational weight(kg)was measured at each prenatal clinical visit using a standardized weight scale.Logistic regression analysis was used to assess the risk of GDM.Interaction analysis and mediation effect analysis were performed in the middle pregnancy model.Results:In the early pregnancy model,the risk of GDM was 0.858 times lower(95%confidence interval[CI]:0.786,0.937)with insufficient GWG(iGWG)and 1.201 times higher(95%CI:1.097,1.316)with excessive GWG after adjustment.In the middle pregnancy model,the risk of GDM associated with iGWG increased 1.595 times(95%CI:1.418,1.794)after adjustment;for excessive GWG,no significant difference was found(P=0.223).Interaction analysis showed no interaction between GWG in early pregnancy(GWG-E)and GWG in middle pregnancy(GWG-M)(F=1.268;P=0.280).The mediation effect analysis indicated that GWG-M plays a partial mediating role,with an effect proportion of 14.9%.Conclusions:eGWG-E and iGWG-M are associated with an increased risk of GDM.Strict control of weight gain in early pregnancy is needed,and sufficient nutrition should be provided in middle pregnancy. | Aiqi Yin Fuying Tian Xiaoxia Wu Yixuan Chen Kan Liu Jianing Tong Xiaonian Guan Huafan Zhang Linlin Wu Jianmin Niu | 2022 | Chinese Medical Journal2022,,9: | 5 |
| 7 | Impact of Temperature on Mortality in Three Major Chinese Cities显示文摘Objective To study the relation between temperature and mortality by estimating the temperature-related mortality in Beijing,Shanghai,and Guangzhou.Methods Data of daily mortality,weather and air pollution in the three cities were collected.A distributed lag nonlinear model was established and used in analyzing the effects of temperature on mortality.Current and future net temperature-related mortality was estimated.Results The association between temperature and mortality was J-shaped,with an increased death risk of both hot and cold temperature in these cities.The effects of cold temperature on health lasted longer than those of hot temperature.The projected temperature-related mortality increased with the decreased cold-related mortality.The mortality was higher in Guangzhou than in Beijing and Shanghai.Conclusion The impact of temperature on health varies in the 3 cities of China,which may have implications for climate policy making in China. | ZHANG Jing LI Tian Tian TAN Jian Guo HUANG Cun Rui KAN Hai Dong | 2014 | Biomedical and Environmental Sciences2014,27,7: | 5 |
| 8 | Effect of coronary bifurcation angle on clinical outcomes in Chinese patients treated with crush stenting: a subgroup analysis from DKCRUSH-1 bifurcation study显示文摘背景分叉角度可以影响压碎 stenting 的临床的结果。我们寻求了比较高度(60 ( | CHEN Shao-liang ZHANG Jun-jie YE Fei CHEN Yun-dai FANG Wei-yi WEI Meng HE Ben SUN Xue-wen YANG Song CHEN Jin-guo SHAN Shou-jie TIAN Nai-liang LI Xiao-bo LIU Zhi-zhong KAN Jing Lee Michael Kwan Tak W | 2009 | Chinese Medical Journal2009,,4: | 5 |
| 9 | Obstructive Sleep Apnea Affecting Platelet Reactivity in Patients Undergoing Percutaneous Coronary Intervention显示文摘 | Xiao-Min Jiang Xue-Song Qian Xiao-Fei Gao Zhen Ge Nai-Liang Tian Jing Kan Jun-Jie Zhang | 2018 | Chinese Medical Journal2018,,9: | 4 |
| 10 | Clinical outcomes after recanalization of a chronic total occluded vessel with bifurcation lesions: results from single-center, prospective, chronic total occlusion registry study显示文摘 | CHEN Shao-liang YE Fei ZHANG Jun-jie KAN Jing LIN Song LIU Zhi-zhong TIAN Nai-liang ZHU Zhong-sheng XU Hai-mei | 2012 | Chinese Medical Journal2012,,6: | 3 |
| 11 | Geochemistry and Geochronology of the Gebunongba Iron Polymetallic Deposit in the Gangdese Belt, Tibet显示文摘The Gebunongba iron polymetallic deposit is a typical skarn deposit located at the westernmost end of the discovered iron polymetallic deposits in the Gangdese metallogenic belt. Major and trace elements of the monzonite granite related to mineralization show that these rocks are peraluminous(ACNK=1.15–1.21) and are rich in Si(76.63 wt.%–76.93 wt.% SiO2), K(K2 O/Na2 O ratio of 1.80–2.30), LREE and LILEs(Rb, Ba, Th, U, Pb), but is depleted in high field strength elements(Nb, Ta, Ti and HREE). In addition, these rocks show obviously negative Eu anomalies(δEu=0.48–0.55). The LA-ICPMS U-Pb age of zircons in monzonite granite is 59.72±0.55 Ma(MSWD=0.79), whereas the 40 Ar/39 Ar age of muscovite in iron ores is 59.22±0.61 Ma(MSWD=16.20). This indicates that the deposit formed at the syn-collision stage of Lhasa-India terrane is later than the northward subduction of the Yajiang crust. The monzonite granite has been probably derived from the partial melting of ancient lower crustal materials, which is probably resulted from the underplating of mantle-derived magmas. It is favorable for the formation of iron polymetallic deposit. Iron polymetallic mineralization is prevalent in Gangdese metallogenic belt at syn-collision stage. Therefore, syn-collision stage is an important mineralization stage for iron polymetallic deposits. The results of this study proved that iron polymetallic mineralization still took place in the western segment of Gangdese metallogenic belt and provided basis for further prospecting the deposits of the same type. | Shunbao Gao Youye Zheng Junsheng Jiang Kan Tian Jin Xu | 2019 | Journal of Earth Science2019,30,2: | 3 |
| 12 | Expression of the human fast-twitch skeletal muscle troponin I cDNA in a human ovarian carcinoma suppresses tumor growth显示文摘To explore the efficiency and mechanism of ovarian carcinoma gene therapy with the human fast-twitch skeletal muscle troponin I gene (TnI-fast), TnI-fast cDNA was transferred into human ovarian adeno-carcinoma cell-line SK-OV-3. In vitro, the cell growth and cell cycle of TnI-fast-, vector-, and mock-transfected cells were determined by MTT and flow cytometry assay, respectively. The condi-tioned media of TnI-fast-, vector-, and mock-transfected SK-OV-3 cells were collected, and the cell pro-liferation inhibiting rates of human umbilical cord venous endothelial cells (HUVECs) by the three conditioned media were assayed. All the three cell lines were implanted into node mice, and the tumor growth, cell apoptosis, angiogenesis, and expression of TnI-fast were observed or analyzed, respec-tively. In vitro, expression of TnI-fast protein had no inhibiting effect on the growth of the dominant and stable transfectant cells, but endothelium, when compared with vector-transfected cells and nontrans-fected parental SK-OV-3 cells. Implantation of stable clone expressing TnI-fast in the female BALB/c nude mice inhibits primary tumor growth by an average of 73%. The nude mice grafts expressing TnI-fast exhibit a significant decrease of microvascular density, a higher rate of tumor cells apoptosis and a comparable proliferation rate as control. Our study, to our knowledge, shows the slowed down growth of the primary ovarian carcinoma, suggested that grafts were self-inhibitory by halting angio-genesis. Our data might also provide a novel useful strategy for cancer therapy by antiangiogenic gene therapy with a specific angiogenesis inhibitor TnI-fast. | XIONG GuangWu1,3, YANG Li2, WEI YuQuan2, WANG ShiLang1, TIAN Ling2, LEI Song2, KAN Bing2 & MAO YongQiu2 1 Department of Obstetrics and Gynecology, Second Huaxi Hospital, Sichuan University, Chengdu 610041, China 2 State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China 3 Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100083, China | 2007 | Science China(Life Sciences)2007,50,1: | 2 |
| 13 | Comparative Study of the Genetic Diversity, Antimicrobial Resistance, and Pathogenicity of Aeromonas Isolates from Clinical Patients and Healthy Individuals显示文摘Objective This study was performed to compare the genetic diversity,virulence,and antimicrobial resistance of Aeromonas strains isolated from patients and healthy individuals.Methods A total of 38 clinical strains and 19 strains from healthy individuals were isolated from the samples collected in Ma’anshan City,Anhui Province.Their taxonomy was investigated using concatenated gyrB-cpn60 sequences,and their resistance to 12 antibiotics was evaluated.The pathogenicity of these strains was examined through beta-hemolysis,protease activity,and virulence gene assays.Results The 57 Aeromonas strains were divided into 55 sequence types.Of these types,21 were novel,suggesting that their genetic diversity was high.These Aeromonas isolates could be divided into 7 species,and the positive rates of beta-hemolysis and protease activity were 49.1%and 73.7%,respectively.The detection rate of clinical patients in terms of beta-hemolysis and protease activity was higher than that of healthy individuals.Among the four most common Aeromonas strains,A.dhakensis had the highest detection rate of virulence genes.The multidrug resistance rate of the clinical isolates was much higher than that of the strains isolated from healthy individuals.Conclusions The taxonomy,virulence properties,and antibiotic resistance of Aeromonas isolates from patients differ from those of the isolates from healthy individuals. | MENG Shuang DU Xiao Li WANG Yong Lu QU Feng Tian XIE Gui Lin ZHOU Hai Jian HU Jin Rui QIN Zheng WANG Yue KAN Biao CUI Zhi Gang | 2021 | Biomedical and Environmental Sciences2021,34,6: | 2 |
| 14 | Intravenous injection of nicardipine changed the distribution of coronary artery endothelial shear stress and fluid dynamics in patients with unstable angina显示文摘 | CHEN Shao-liang HU Zuo-ying ZHANG Jun-jie KAN Jing XU Tian LIU Zhi-zhong XU Hai-mei | 2012 | Chinese Medical Journal2012,,18: | 2 |
| 15 | Spectroscopic characterization of effective components anthraquinones in Chinese medicinal herbs binding with serum albumins显示文摘 | Shuyun Bi Daqian Song Yuhe Kan Dong Xu Yuan Tian Xin Zhou Hanqi Zhang | 2005 | Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy2005,,1: | 2 |
| 16 | An enhanced method for nucleic acid detection with CRISPR-Cas12a using phosphorothioate modified primers and optimized gold-nanopaticle strip显示文摘CRISPR-Cas12a system has been shown promising for nucleic acid diagnostics due to its rapid,portable and accurate features.However,cleavage of the amplicons and primers by the cis-and trans-activity of Cas12a hinders the attempts to integrate the amplification and detection into a single reaction.Through phosphorothioate modification of primers,we realized onepot detection with high sensitivity using plasmids of SARS-CoV-2,HPV16 and HPV18.We also identified the activated Cas12a has a much higher affinity to C nucleotide-rich reporter than others.By applying such reporters,the reaction time required for a lateral-flow readout was significantly reduced.Furthermore,to improve the specificity of the strip-based assay,we created a novel reporter and,when combined with a customized gold-nanopaticle strip,the readout was greatly enhanced owing to the elimination of the nonspecific signal.This established system,termed Targeting DNA by Cas12a-based Eye Sight Testing in an Onepot Reaction(TESTOR),was validated using clinical cervical scrape samples for human papillomaviruses(HPVs)detection.Our system represents a general approach to integrating the nucleic acid amplification and detection into a single reaction in CRISPR-Cas systems,highlighting its potential as a rapid,portable and accurate detection platform of nucleic acids. | Jiaojiao Gong Lijuan Kan Xiuming Zhang Ying He Jiaqiang Pan Liping Zhao Qianyun Li Menghao Liu Jie Tian Sili Lin Zhouyu Lu Liang Xue Chaojun Wang Guanghui Tang | 2021 | Bioactive Materials2021,6,12: | 1 |
| 17 | Effect of carbon nanotubes on the properties of ZrB2-SIC ceramics 显示文摘 | Tian Wu-bian Kan Yan-mei Zhang Guo-jun | 2008 | Mater Sci Engin A2008,487,12: | 1 |
| 18 | Shipping emissions associated with increased cardiovascular hospitalizations显示文摘 | Linwei Tian Kin-fai Ho Peter K.K. Louie Hong Qiu Vivian C. Pun Haidong Kan Ignatius T.S. Yu Tze Wai Wong | 2013 | Atmospheric Environment2013,,: | 1 |
| 19 | Hemodynamic change in wall shear stress in patients with coronary bifurcation lesions treated by double kissing crush or single-stent technique显示文摘 | CHEN Shao-liang KAN Jing ZHANG Jun-jie HU Zuo-ying XU Tian | 2012 | Chinese Medical Journal2012,,10: | 1 |
| 20 | Effect of carbon nanotubes on the properties of ZrB2-SiC ceramics显示文摘 | Tian W B Kan Y M Zhang G J | | 0,,: | 1 |