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| 1 | AXL is a candidate receptor for SARS-CoV-2 that promotes infection of pulmonary and bronchial epithelial cells显示文摘The current coronavirus disease 2019(COVID-19)pandemic presents a global public health challenge.The viral pathogen responsible,severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),binds to the host receptor ACE2 through its spike(S)glycoprotein,which mediates membrane fusion and viral entry.Although the role of ACE2 as a receptor for SARS-CoV-2 is clear,studies have shown that ACE2 expression is extremely low in various human tissues,especially in the respiratory tract.Thus,other host receptors and/or co-receptors that promote the entry of SARS-CoV-2 into cells of the respiratory system may exist.In this study,we found that the tyrosine-protein kinase receptor UFO(AXL)specifically interacts with the N-terminal domain of SARS-CoV-2 S.Using both a SARS-CoV-2 virus pseudotype and authentic SARS-CoV-2,we found that overexpression of AXL in HEK293T cells promotes SARS-CoV-2 entry as efficiently as overexpression of ACE2,while knocking out AXL significantly reduces SARS-CoV-2 infection in HI 299 pulmonary cells and in human primary lung epithelial cells.Soluble human recombinant AXL blocks SARS-CoV-2 infection in cells expressing high levels of AXL.The AXL expression level is well correlated with SARS-CoV-2 S level in bronchoalveolar lavage fluid cells from COVID-19 patients.Taken together,our findings suggest that AXL is a novel candidate receptor for SARS-CoV-2 which may play an important role in promoting viral infection of the human respiratory system and indicate that it is a potential target for future clinical intervention strategies. | Shuai Wang Zongyang Qiu Yingnan Hou Xiya Deng Wei Xu Tingting Zheng Peihan Wu Shaofang Xie Weixiang Bian Chong Zhang Zewei Sun Kunpeng Liu Chao Shan Aifu Lin Shibo Jiang Youhua Xie Qiang Zhou Lu Lu Jing Huang Xu Li | 2021 | Cell Research2021，31，2： | 39 |
| 2 | Antimony smelting process generating solid wastes and dust:Characterization and leaching behaviors显示文摘A large amount of solid waste has been produced by the antimony smelting process in the'World Capital of Antimony', Xikuangshan area in China. This study comprehensively investigated the physical and chemical characteristics of the various solid wastes, as well as the leaching behavior of the solid wastes, which included water-quenched slag,arsenic-alkali residue, desulfurized slag and blast furnace dust. These four types of waste were enriched in a variety of heavy metals and metalloids and more specifically with As and Sb levels up to 8.6 × 104 and 3.16 × 105mg/kg, respectively, in arsenic-alkali residue. For desulfurized slag and water-quenched slag, the leaching concentration of Sb significantly exceeded the acceptable limits during the leaching tests using the toxicity characteristic leaching procedure and the synthetic precipitation leaching procedure. In addition, As leaching in arsenic-alkali residue was extraordinarily hazardous, being three orders of magnitude higher than the regulatory level of As. According to the results of the extraction tests, all the tested wastes were classified as hazardous waste. | Xuejun Guo Kunpeng Wang Mengchang He Ziwei Liu Hailin Yang Sisi Li | 2014 | Journal of Environmental Sciences2014，26，7： | 13 |
| 3 | Thermally conductive polyvinyl alcohol composite films via introducing hetero-structured MXene@silver fillers显示文摘Ag nanoparticles were in-situ grown on the surface of MXene nanosheets to prepare thermally conductive hetero-structured MXene@Ag fillers.With polyvinyl alcohol(PVA)as the polymer matrix,thermally conductive MXene@Ag/PVA composite films were fabricated by the processes of solution blending,pouring,evaporative self-assembly.With the same mass fraction,MXene@Ag-III(MXene/Ag,2:1,w/w)presents more significant improvement in thermal conductivity coefficient(λ)than MXene@Ag,single MXene,Ag,simply blending MXene/Ag.MXene@Ag-III/PVA composite films show dual functions of excellent thermal conductivity and electromagnetic interference(EMI)shielding.When the mass fraction of MXene@Ag-III is 60 wt.%,the in-planeλ(λ_(∥)),through-planeλ(λ_(⊥)),EMI shielding effectiveness(EMI SE)are 3.72 and 0.41 W/(m∙K),32 dB,which are increased by 3.1,1.3,105.7 times than those of pure PVA film(0.91 and 0.18 W/(m∙K),0.3 dB),respectively.The 60 wt.%MXene@Ag-III/PVA composite film also has satisfying mechanical and thermal properties,with Young’s modulus,glass transition temperature,heat resistance index of 3.8 GPa,58.5 and 175.3℃,respectively. | Mukun Li Yuyao Sun Dianying Feng Kunpeng Ruan Xia Liu Junwei Gu | 2023 | Nano Research2023，16，5： | 10 |
| 4 | Cubic surface fitting to image by combination显示文摘We present a new method for constructing a fitting surface to image data. The new method is based on a supposition that the given image data are sampled from an original scene that can be represented by a surface defined by piecewise quadratic polynomials. The surface representing the original scene is known as the original surface in this paper. Unlike existing methods, which generally construct the fitting surface to the original surface using image data as interpolation data, the new method constructs the fitting surface using the image data as constraints to reverse the sampling process, which improves the approximation precision of the fitting surface. Associated with each data point and its near region, the new method constructs a quadratic polynomial patch locally using the sampling formula as constraint. The quadratic patch approximates the original surface with a quadratic polynomial precision. The fitting surface which approximates the original surface is formed by the combination of all the quadratic polynomial patches. The experiments demonstrate that compared with Bi-cubic and Separable PCC methods, the new method produced resized images with high precision and good quality. | LI XueMei ZHANG CaiMing YUE YiZhen WANG KunPeng | 2010 | Science China(Information Sciences)2010，53，7： | 7 |
| 5 | Electrically controllable laser frequency combs in graphene-fibre microresonators显示文摘Laser frequency combs emitting ultrafast pulses of light,at equidistantly discrete frequencies,are cornerstones of modern information networks.In recent years,the generation of soliton combs in microcavities with ultrahighquality factors has established microcombs as out-oflaboratory tools.However,the material and geometry of a laser cavity,which determine comb formation,are difficult to electrically tune.Such dynamic control can further enrich the diversity of comb outputs and help to actively stabilize them. | Chenye Qin Kunpeng Jia Qianyuan Li Teng Tan Xiaohan Wang Yanhong Guo Shu-Wei Huang Yuan Liu Shining Zhu Zhenda Xie Yunjiang Rao Baicheng Yao | 2020 | Light(Science & Applications)2020，9，1： | 5 |
| 6 | Thyristor Junction Temperature Estimation Based on Measured Temperature of Molybdenum Flat显示文摘为获得较准确的晶闸管结温,提出了基于晶闸管钼层实测温度计算结温的共扼梯度算法。分析了共轭梯度法用于求解结温的具体步骤,并通过FORTRAN语言编译形成LOG命令流,导入ANSYS软件中来实现算法,该方法对于未知的低频分量,以较少的迭代次数即可以得到准确解,对于未知的高频分量,通过多次的迭代也能够获得准确的返溯值,因而具备处理多个未知量且收敛速度快的优点。以KPD3000-72型晶闸管应用于直流输电领域为例,分别在直流稳态、单波次浪涌电流和3波次浪涌电流的试验条件下进行计算,结果表明所得结温准确,为传统热阻抗法提供了校核的依据。 | ZHANG Chunyu LI Chengrong HAN Xiaohui ZHA Kunpeng TANG Guangfu | 2012 | 中国电机工程学报2012，32，22： | 5 |
| 7 | Molecular architecture of the luminal ring of the Xenopus laevis nuclear pore complex显示文摘The nuclear pore complex(NPC)mediates the flow of substances between the nucleus and cytoplasm in eukaryotic cells.Here we report the cryo-electron tomography(cryo-ET)structure of the luminal ring(LR)of the NPC from Xenopus laevis oocyte.The observed key structural features of the LR are independently confirmed by single-particle cryo-electron microscopy(cryo-EM)analysis.The LR comprises eight butterfly-shaped subunits,each containing two symmetric wings.Each wing consists of four elongated,tubular protomers.Within the LR subunit,the eight protomers form a Finger domain,which directly contacts the fusion between the inner and outer nuclear membranes and a Grid domain,which serves as a rigid base for the Finger domain.Two neighboring LR subunits interact with each other through the lateral edges of their wings to constitute a Bumper domain,which displays two major conformations and appears to cushion neighboring NPCs.Our study reveals previously unknown features of the LR and potentially explains the elastic property of the NPC. | Yanqing Zhang Sai Li Chao Zeng Gaoxingyu Huang Xuechen Zhu Qifan Wang Kunpeng Wang Qiang Zhou Chuangye Yan Wusheng Zhang Guangwen Yang Minhao Liu Qinghua Tao Jianlin Lei Yigong Shi | 2020 | Cell Research2020，30，6： | 4 |
| 8 | Influence of transboundary air pollution on air quality in southwestern China显示文摘Air pollution is a grand challenge of our time due to its multitude of adverse impacts on environment and society,with the scale of impacts more severe in developing countries,including China.Thus,China has initiated and implemented strict air pollution control measures over last several years to reduce impacts of air pollution.Monitoring data from Jan 2015 to Dec 2019 on six criteria air pollutants(SO_(2),NO_(2),CO,O_(3),PM_(2.5),and PM_(10))at eight sites in southwestern China were investigated to understand the situation and analyze the impacts of transboundary air pollutants in this region.In terms of seasonal variation,the maximum concentrations of air pollutants at these sites were observed in winter or spring season depending on individual site.For diurnal variation,surface ozone peaked in the afternoon while the other pollutants had a bimodal pattern with peaks in the morning and late afternoon.There was limited transport of domestic emissions of air pollutants in China to these sites.Local emissions enhanced the concentrations of air pollutants during some pollution events.Mostly,the transboundary transport of air pollution from South Asia and Southeast Asia was associated with high concentrations of most air pollutants observed in southwestern China.Since air pollutants can be transported to southwestern China over long distances from the source regions,it is necessary to conduct more research to properly attribute and quantify transboundary transport of air pollutants,which will provide more solid scientific guidance for air pollution management in southwestern China. | Xiufeng Yin Shichang Kang Maheswar Rupakheti Benjamin de Foy Ping Li Junhua Yang Kunpeng Wu Qianggong Zhang Dipesh Rupakheti | 2021 | Geoscience Frontiers2021，12，6： | 4 |
| 9 | Estimation of Crop Biomass Using GF-3 Polarization SAR Data Based on Genetic Algorithm Feature Selection显示文摘In recent years,Polarization SAR(PolSAR)has been widely used in the filed of crop biomass estimation.However,high dimensional features extracted from PolSAR data will lead to information redundancy which will result in low accuracy and poor transfer ability of the estimation model.Aiming at this problem,we proposed a estimation method of crop biomass based on automatic feature selection method using genetic algorithm(GA).Firstly,the backscattering coefficient,the polarization parameters and texture features were extracted from PolSAR data.Then,these features were automatically pre-selected by GA to obtain the optimal feature subset.Finally,based on this subset,a support vector regression machine(SVR)model was applied to estimate crop biomass.The proposed method was validated using the GaoFen-3(GF-3)QPSΙ(C-band,quad-polarization)SAR data.Based on wheat and rape biomass samples acquired from a synchronous field measurement campaign,the proposed method achieve relative high validation accuracy(over 80%)in both crop types.For further analyzing the improvement of proposed method,validation accuracies of biomass estimation models based on several different feature selection methods were compared.Compared with feature selection based on linear correlation,GA method has increased by 5.77%in wheat biomass estimation and 11.84%in rape biomass estimation.Compared with the method of recursive feature elimination(RFE)selection,the proposed method has improved crops biomass estimation accuracy by 3.90%and 5.21%,respectively. | Kunpeng XU Lei ZHAO Kun LI Erxue CHEN Wangfei ZHANG Hao YANG | 2020 | Journal of Geodesy and Geoinformation Science2020，3，4： | 3 |
| 10 | Design of Microstructure Parameters on a Small Multi-Throttle Aerostatic Guideway in Photolithography显示文摘A compact multi-throttle aerostatic guideway is the preferred structure for high precision and acceleration motion in the variable-slit system(VS)of photolithography.The presence of microstructure,such as recesses and grooves,on the guideway working surface has been found to improve the loading performance.Nevertheless,the effects on the guideway performance of changing the microstructure on the micron level are not yet clear.The mesh adaptation method,which was proposed by the authors,is employed in this paper to quantitatively study the influences of four microstructure parameters.The effect of tuning these parameters on the loading performance is revealed.The level of impact determines the proposed design process of the parameters.The characteristic feature of the proposed design process is that the working points of carrying capacity,stiffness,and rotational stiffness are unified under twoway adjusting by means of recess parameters.According to the proposed design process and tuning method,the restriction of supply pressure is lifted to a certain extent and the mutual tradeoff among the loading performances is relieved.The experimental results show that the rotational stiffness of the designed guideway,based on the tuned parameters,reached 2.14×10^(4) Nmrad1 and increased by 69.8%.In a scanning test of the applied VS on argon fluoride laser(ArF)photolithography,the average scanning acceleration reached 67.5 m·s^(-2),meeting the design specification. | Zhongpu Wen Jianwei Wu Kunpeng Xing Yin Zhang Jiean Li Jiubin Tan | 2021 | Engineering2021，7，2： | 3 |
| 11 | Montgomery Algorithm over a Prime Field显示文摘New formulae for point addition and point doubling on elliptic curves over prime fields are presented.Based on these formulae, an improved Montgomery algorithm is proposed. The theoretical analysis indicates that it is about 13.4% faster than Brier and Joye's Montgomery algorithm. Experiments on the elliptic curve over a 256-bit prime field recommended by the National Institute of Standards and Technology and over a 256-bit prime field in Chinese elliptic curve standard SM2 support the theoretical analysis. | YU Wei WANG Kunpeng LI Bao TIAN Song | 2019 | Chinese Journal of Electronics2019，28，1： | 2 |
| 12 | Economy Analysis of Flexible LCC-HVDC Systems with Controllable Capacitors显示文摘Commutation failure(CF)is a frequent dynamic event at inverter of LCC-HVDC systems caused by AC side faults which can lead to inverter blocking,interruption of active power transfer,and even system blackout.To eliminate CFs and improve system performance,new Flexible LCC-HVDC topologies have been proposed in previous research but with limited analysis on its economic performance.Therefore,to further validate the applicability of Flexible LCC-HVDC topologies,this paper utilizes Life-Cycle Cost Analysis model to analyze the life-cycle cost of inverter stations for conventional LCCHVDC,Capacitor Commutated Converter based HVDC(CCCHVDC)topology and Flexible LCC-HVDC topologies including Controllable Capacitor based Flexible LCC-HVDC,AC Filterless Controllable Capacitor based Flexible LCC-HVDC and improved Flexible LCC-HVDC.Through a case study based on a 500 kV,1000 MW LCC-HVDC scheme,comparison results show that the AC Filterless Controllable Capacitor based Flexible LCCHVDC topology and the improved Flexible LCC-HVDC topology have lower cost than the conventional LCC-HVDC and CCCHVDC topologies,which proves that the elimination of CFs can be achieved with reduced cost. | Nan Chen Kunpeng Zha Haitao Qu Fangling Li Ying Xue Xiao-Ping Zhang | 2022 | CSEE Journal of Power and Energy Systems2022，8，6： | 2 |
| 13 | Three-dimensional structure of the hepatitis B core antigen particle truncated at residue 154显示文摘The three-dimensional structure of recombinant hepatitis B core antigen(HBcAg) particles truncated at residue 154(HBcAg-154) was determined to 7.8 ? resolution by cryo-electron microscopy(cryoEM) and computer reconstruction.The capsid of HBcAg-154 is mainly constituted by α-helical folds,highly similar to that of HBcAg-149.The C-terminal region between residues 155 and 183 of the core protein is more crucial to the encapsidation of RNA,and the short C-terminal tail of HBcAg-154 results in a nearly empty capsid. | LIU ShuYu HE Jian LI KunPeng DAI AGuang CAI ChangJie ZHANG JingQiang | 2011 | Science China(Life Sciences)2011，54，2： | 2 |
| 14 | Liquid crystalline texture and hydrogen bond on the thermal conductivities of intrinsic thermal conductive polymer films显示文摘Polymer-dispersed liquid crystal(PDLC)films comprising polyvinyl alcohol(PVA)and liquid crystal monomer(LCM)were successfully obtained by the method of solution casting&thermal compressing.LCM was distributed orderly in PVA matrix by hydrogen bond interaction,to form PVA-LCM interpe net rating-layered networks.When the mass fraction of LCM was up to 35 wt%,the corresponding in-plane thermal conductivity coefficient(λ//)of PDLC film was significantly increased to 1.41 W m^(-1)K^(-1),about 10.8 times that of neat PVA(0.13 W m^(-1)K^(-1)).High intrinsicλ//values of PDLC films were mainly attributed to the formed microscopic-ordered structures from ordered stacking of LCM,ordered arrangement of PVA chains,and their hydrogen bond interaction.This work would offer a new way to design and prepare novel intrinsic high thermal conductive polymers. | Ying Li Changdan Gong Chenggong Li Kunpeng Ruan Chao Liu Huan Liu Junwei Gu | 2021 | Journal of Materials Science & Technology2021，，23： | 2 |
| 15 | C60intercalating Ti_(3)C_(2)T_(x) MXenes assisted by γ-cyclodextrin for electromagnetic interference shielding films with high stability显示文摘Ti_(3)C_(2)T_(x)MXenes with excellent metallic conductivity and flexibility have shown a promising prospect as electromagnetic interference(EMI) shielding materials. Ultrathin, hierarchical hybrid films were fabricated by using C60intercalating Ti_(3)C_(2)T_(x)MXenes with the assistance of water-soluble γ-cyclodextrin(CD). The C_(60)/CD complex was obtained by high-speed vibration milling using hydrophilic CD as dispersing agent. After thermal annealing treatment, the obtained hybrid film exhibited excellent EMI shielding(53.52±0.43 dB), hydrophobicity(water contact angle: 93.7°) and mechanical stability(over 0.9 million bending times). Taking advantage of the antioxidant of C_(60), the chemical durability of Ti_(3)C_(2)T_(x) MXenes based hybrid films was also improved as expected. These results indicate that the well-designed hierarchical hybrid films with the intercalation of C_(60) have promising potential for high-performance EMI shielding applications. | Kunpeng Qian Shuang Li Jianhui Fang Yuhuan Yang Shaomei Cao Miao Miao Xin Feng | 2022 | Journal of Materials Science & Technology2022，，32： | 2 |
| 16 | Transport of dissolved oxygen at the sediment-water interface in the spanwise oscillating flow显示文摘The distribution and concentration of dissolved oxygen(DO)play important roles in aerobic heterotroph activities and some slow chemical reactions,and can affect the water quality,biological communities,and ecosystem functions of rivers and lakes.In this work,the transport of high Schmidt number DO at the sediment-water interface of spanwise oscillating flow is investigated.The volume-averaged Navier-Stokes(VANS)equations and Monod equation are used to describe the flow in the sediment layer and the sediment oxygen demand of microorganisms.The phase-averaged velocities and concentrations of different amplitudes and periods are studied.The dependence of DO transfer on the amplitude and period is analyzed by means of phase-average statistical quantities.It is shown that the concentration in the sediment layer is positively correlated with the turbulence intensity,and the DO concentration and penetration depth in the sediment layer increases when the period and amplitude of the oscillating flow increase.Moreover,in the presence of oscillating flow,a specific scaling relationship exists between the Sherwood number/oxygen consumption of aerobic heterotrophs and the Reynolds number. | Kunpeng WANG Qingxiang LI Yuhong DONG | 2021 | Applied Mathematics and Mechanics(English Edition)2021，42，4： | 2 |
| 17 | Subdivision Surface-Based Isogeometric Boundary Element Method for Steady Heat Conduction Problems with Variable Coefficient显示文摘The present work couples isogeometric analysis(IGA)and boundary element methods(BEM)for three dimensional steady heat conduction problems with variable coefficients.The Computer-Aided Design(CAD)geometries are built by subdivision surfaces,and meantime the basis functions of subdivision surfaces are employed to discretize the boundary integral equations for heat conduction analysis.Moreover,the radial integration method is adopted to transform the additional domain integrals caused by variable coefficients to the boundary integrals.Several numerical examples are provided to demonstrate the correctness and advantages of the proposed algorithm in the integration of CAD and numerical analysis. | Xiuyun Chen Xiaomeng Yin Kunpeng Li Ruhui Cheng Yanming Xu Wei Zhang | 2021 | Computer Modeling in Engineering & Sciences2021，，10： | 1 |
| 18 | 2 μm optical frequency comb generation via optical parametric oscillation from a lithium niobate optical superlattice box resonator显示文摘Optical parametric oscillators(OPOs) can downconvert the pump laser to longer wavelengths with octave separation via χ^((2)), which is widely used for laser wavelength extension including mid-infrared(MIR) generation.Such a process can be integrated in monolithic resonators, being compact and low in threshold. In this work, we show that the monolithic χ^((2))mini-OPO can also be used for optical frequency comb generation around 2096 nm and enters the boundary of MIR range. A new geometry called an optical superlattice box resonator is developed for this realization with near-material-limited quality factor of 4.0 × 10^(7). Only a continuous-wave near-infrared pump laser is required, with OPO threshold of 80 mW and output power up to 340 mW. Revival temporal profiles are measured at a detectable repetition frequency of 1.426 GHz, and narrow beat note linewidth of less than 10 Hz shows high comb coherence. These results are in good agreement with our simulation for a stable comb generation. Such an OPO-based comb source is useful for carbon dioxide sensing or the mine prospect applications and can be generalized to longer MIR wavelengths for general gas spectroscopy. | Xiaohan Wang Kunpeng Jia Mengwen Chen Shanshan Cheng Xin Ni Jian Guo Yihao Li Huaying Liu Liyun Hao Jian Ning Gang Zhao Xinjie Lv Shu-Wei Huang Zhenda Xie Shi-Ning Zhu | 2022 | Photonics Research2022，10，2： | 1 |
| 19 | A highly efficient and selective catalyst for liquid phase hydrogenation of maleic anhydride to butyric acid 显示文摘 | Xu Jian Sun Kunpeng Zhang Li | 2005 | Catalysis Communications2005，6，7： | 1 |
| 20 | A novel synthesis route of butyric acid from hydrogenation of maleic anhydride over Pd/TiO2 catalysts 显示文摘 | Xu Jian Sun Kunpeng Zhang Li | 2006 | Catalysis Letters2006，107，： | 1 |
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