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| 1 | Extended surgical resection for xanthogranulomatous cholecystitis mimicking advanced gallbladder carcinoma: A case report and review of literature显示文摘Xanthogranulomatous 胆汁(XGC ) 是胆囊的破坏煽动性的疾病,很少包含邻近的机关并且模仿国王先进胆囊癌。诊断在病理学的检查以后仅仅通常是可能的。46 42 岁的女人被指我们包含肝核,正确的肝脑叶,恰好结肠的弯曲,和十二指肠的怀疑的胆囊癌症的中心。刷细胞学获得了由内视镜后退胆管造影术(ERC ) 出现了高级发育异常。病人经历了团的在团体切除术,由正确叶切除术,正确的半结肠切除术,和部分十二指肠的切除术组成。出人意料地揭示的病理学的检查一 XGC.Only,为有邻近的机关的直接参与的 XGC 的扩大外科的切除术的六个案例到目前为止被报导了。在这些情况中,与癌给 XGC 的可能的共存,恶意不能被排除,甚至在细胞学和 intraoperative 冰冻切片调查以后。在结论,由于源于在另外的方面上包围机关的高度好攻击的煽动性的侵略的一个方面和可能的复杂并发症上的胆囊癌的差的预后,它似乎这些案例应该被当作恶性瘤直到不那样证明。临床医生们应该包括 XGC 在之中可能微分在肝核群众诊断。 | Antonino Spinelli Guido Schumacher Andreas Pascher Enrique Lopez-Hanninen Hussain Al-Abadi Christoph Benckert Igor M Sauer Johann Pratschke Ulf P Neumann Sven Jonas Jan M Langrehr Peter Neuhaus | 2006 | World Journal of Gastroenterology2006，12，14： | 13 |
| 2 | Biodegradable magnesium barrier membrane used for guided bone regeneration in dental surgery显示文摘Barrier membranes are commonly used as part of the dental surgical technique guided bone regeneration(GBR)and are often made of resorbable collagen or non-resorbable materials such as PTFE.While collagen membranes do not provide sufficient mechanical protection of the covered bone defect,titanium reinforced membranes and non-resorbable membranes need to be removed in a second surgery.Thus,biodegradable GBR membranes made of pure magnesium might be an alternative.In this study a biodegradable pure magnesium(99.95%)membrane has been proven to have all of the necessary requirements for an optimal regenerative outcome from both a mechanical and biological perspective.After implantation,the magnesium membrane separates the regenerating bone from the overlying,faster proliferating soft tissue.During the initial healing period,the membrane maintained a barrier function and space provision,whilst retaining the positioning of the bone graft material within the defect space.As the magnesium metal corroded,it formed a salty corrosion layer and local gas cavities,both of which extended the functional lifespan of the membrane barrier capabilities.During the resorption of the magnesium metal and magnesium salts,it was observed that the membrane became surrounded and then replaced by new bone.After the membrane had completely resorbed,only healthy tissue remained.The in vivo performance study demonstrated that the magnesium membrane has a comparable healing response and tissue regeneration to that of a resorbable collagen membrane.Overall,the magnesium membrane demonstrated all of the ideal qualities for a barrier membrane used in GBR treatment. | Patrick Rider Zeljka Peric Kacarevic Akiva Elad Drazen Tadic Daniel Rothamel Gerrit Sauer Fabien Bornert Peter Windisch David Botond Hangyasi Balint Molnar Emely Bortel Bernhard Hesse Frank Witte | 2022 | Bioactive Materials2022，7，8： | 7 |
| 3 | Biliary phosphatidylcholine and lysophosphatidylcholine profiles in sclerosing cholangitis显示文摘AIM:To analyze phospholipid profiles in intrahepatic bile from patients with primary sclerosing cholangitis(PSC)and secondary sclerosing cholangitis(SSC).METHODS:Intrahepatic bile specimens collected via endoscopic retrograde cholangiography from 41 patients were analyzed.Fourteen of these patients were diagnosed with PSC,10 with SSC,11 with choledocholithiasis or no identifiable biliary disease,and 6 with cholangiocellular carcinoma(CCC).Bile acid,cholesterol,protein,and bilirubin contents as well as pancreas lipase activity in bile were determined by biochemical methods.Phosphatidylcholine(PC)and lysophosphatidylcholine(LPC)species were quantified using nanoelectrospray ionization tandem mass spectrometry.RESULTS:Bile from all the examined patient groups showed a remarkably similar PC and LPC species composition,with only minor statistical differences.Total biliary PC concentrations were highest in controls(8030±1843 mol/L)and lowest in patients with CCC(1969±981 mol/L)(P=0.005,controls vs SSC and CCC,respectively,P<0.05).LPC contents in bile were overall low(4.2%±1.8%).Biliary LPC/PC ratios and ratios of biliary PC to bilirubin,PC to cholesterol,PC to protein,and PC to bile acids showed no intergroup differences.CONCLUSION:PC and LPC profiles being similar in patients with or without sclerosing cholangitis,these phospholipids are likely not of major pathogenetic importance in this disease group. | Annika Gauss Robert Ehehalt Wolf-Dieter Lehmann Gerhard Erben Karl-Heinz Weiss Yvonne Schaefer Petra Kloeters-Plachky Adolf Stiehl Wolfgang Stremmel Peter Sauer Daniel Nils Gotthardt | 2013 | World Journal of Gastroenterology2013，19，33： | 3 |
| 4 | Effect of thiol antioxidant on body fat and insulin reactivity显示文摘 | Wulf Hildebrandt Andreas Hamann Holger Krakowski-Roosen Ralf Kinscherf Klaus Dugi Roland Sauer Sabrina Lacher Nuria N?bel Anne Bodens Vassiliki Bellou Lutz Edler Peter Nawroth Wulf Dr?ge | 2004 | Journal of Molecular Medicine2004，，5： | 1 |
| 5 | Donor evaluation, donor risks, donor outcome, and donor quality of life in adult-to-adult living donor liver transplantation显示文摘 | Andreas Pascher Igor M. Sauer Marc Walter Enrique Lopez-Haeninnen Tom Theruvath Antonino Spinelli Ruth Neuhaus Utz Settmacher Andrea R. Mueller Thomas Steinmueller Peter Neuhaus | 2002 | Liver Transplantation2002，，9： | 1 |
| 6 | CYP3A activity in severe liver cirrhosis correlates with C hild– P ugh and model for end‐stage liver disease ( MELD ) scores显示文摘 | Albader Albarmawi David Czock Annika Gauss Robert Ehehalt Justo Lorenzo Bermejo Jürgen Burhenne Tom M. Ganten Peter Sauer Walter E. Haefeli | 2014 | Br J Clin Pharmacol2014，，1： | 1 |
| 7 | Time course of microglia activation and apoptosis in various brain regions after permanent focal cerebral ischemia in mice显示文摘 | Katrin Rupalla Peter R. Allegrini Dirk Sauer C. Wiessner | 1998 | Acta Neuropathologica1998，，2： | 1 |
| 8 | Surgical Treatment of Primary Hepatic Epithelioid Hemangioendothelioma显示文摘 | Arianeb Mehrabi Arash Kashfi Peter Schemmer Peter Sauer Jens Encke Hamidreza Fonouni Helmut Friess Jürgen Weitz Jan Schmidt Markus W. Büchler Thomas W. Kraus | 2005 | Transplantation (S Suppl)2005，，1： | 1 |
| 9 | Technical and clinical outcome of transjugular intrahepatic portosystemic stent shunt: Bare metal stents (BMS) versus viatorr stent-grafts (VSG)显示文摘 | Christof M. Sommer Theresa L. Gockner Ulrike Stampfl Nadine Bellemann Peter Sauer Tom Ganten Juergen Weitz Hans U. Kauczor Boris A. Radeleff | 2011 | European Journal of Radiology2011，，9： | 1 |
| 10 | Bacteriobilia and fungibilia are associated with outcome in patients with endoscopic treatment of biliary complications after liver transplantation显示文摘 | Daniel Gotthardt Karl Weiss Christian Rupp Konrad Bode Isabella Eckerle Gerda Rudolph Janine Bergemann Petra Kloeters-Plachky Fadi Chahoud Markus Büchler Peter Schemmer Wolfgang Stremmel Peter Sauer | 2013 | Endoscopy2013，，： | 1 |
| 11 | Towards awind farm reduced-order model显示文摘 | Hector A Pulgar Painemal Peter W Sauer | 2011 | Electric PowerSystems Research2011，81，8： | 1 |
| 12 | Successful combination of direct antiviral agents in livertransplanted patients with recurrent hepatitis C virus显示文摘AIM To analyze the safety and efficiency of direct-actingantiviral(DAA) regimens in liver-transplanted patients with hepatitis C virus(HCV) reinfection.METHODS Between January 2014 and December 2016, 39 patients with HCV reinfection after liver transplantation were treated at our tertiary referral center with sofosbuvir(SOF)-based regimens, including various combinations with interferon(IFN), daclatasvir(DAC), simeprivir(SIM) and/or ledipasvir(LDV). Thirteen patients were treated with SOF + IFN ± RBV. Ten patients were treated with SOF + DAC ± RBV. Fiveteen patients were treated with fixed-dose combination of SOF + LDV ± RBV. One patient was treated with SOF + SIM + RBV. Three patients with relapse were retreated with SOF + LDV + RBV. The treatment duration was 12-24 wk in all cases. The decision about the HCV treatment was made by specialists at our transplant center, according to current available or recommended medications.RESULTS The majority of patients were IFN-experienced(29/39, 74.4%) and had a history of hepatocellular carcinoma(26/39, 66.7%) before liver transplantation. Sustained virological response at 12 wk(SVR12) was achieved in 10/13(76.9%) of patients treated with SOF + IFN ± RBV. All patients with relapse were treated with fixed-dose combination of SOF + LDV + RBV. Patients treated with SOF + DAC + RBV or SOF + LDV + RBV achieved 100% SVR12. SVR rates after combination treatment with inhibitors of the HCV nonstructural protein(NS)5 A and NS5 B for 24 wk were significantly higher, as compared to all other therapy regimens(P = 0.007). Liver function was stable or even improved in the majority of patients during treatment. All antiviral therapies were safe and well-tolerated, without need of discontinuation of treatment or dose adjustment of immunosuppression. No serious adverse events or any harm to the liver graft became overt. No patient experienced acute cellular rejection during the study period. CONCLUSION Our cohort of liver-transplanted patients achieved high rates of SVR12 after a 24-wk course of treatment, especially with combination of NS5 A and NS5 B inhibitors. | Christian Rupp Theresa Hippchen Manuel Neuberger Peter Sauer Jan Pfeiffenberger Wolfgang Stremmel Daniel Nils Gotthardt Arianeb Mehrabi Karl-Heinz Weiss | 2018 | World Journal of Gastroenterology2018，24，12： | 1 |
| 13 | Adjuvant versus Neoadjuvant Radiochemotherapy for Locally Advanced Rectal Cancer A Progress Report of a Phase-III Randomized Trial (Protocol CAO/ARO/AIO-94)显示文摘 | Rolf Sauer Rainer Fietkau Christian Wittekind Peter Martus Claus R?del Werner Hohenberger Gerhard Jatzko Hubert Sabitzer Johann-Hinrich Karstens Heinz Becker Clemens Hess Rudolf Raab | 2001 | Strahlentherapie und Onkologie2001，，4： | 1 |
| 14 | New designer drugα-pyrrolidinovalerophenone(PVP):studies on its metabolismand toxicological detection in rat urine using gaschromatographic/mass spectrometric techniques显示文摘 | Sauer C Peters F T Haas C | 2009 | J MassSpectrom2009，44，6： | 1 |
| 15 | Histone hypomethylation is an indicator of epigenetic plasticity in quiescent lymphocytes显示文摘 | BAXTER J SAUER S PETERS A | | 0，，22： | 1 |
| 16 | The vanilloid receptor TRPV1 is activated and sensitized by local anesthetics in rodent sensory neurons显示文摘 | Leffler Andreas Fischer Michael J Rehner Dietlinde Kienel Stephanie Kistner Katrin Sauer Susanne K Gavva Narender R Reeh Peter W Nau Carla | 2008 | Journal of Clinical Investigation2008，，： | 1 |
| 17 | Efficacy of Radiochemotherapy with Platin Derivatives Compared to Radiotherapy Alone in Organ-Sparing Treatment of Bladder Cancer显示文摘 | Rolf Sauer Stefan Birkenhake Reinhard Kühn Christian Wittekind Karl Michael Schrott Peter Martus | 1998 | International Journal of Radiation Oncology Biology Physics1998，，1： | 1 |
| 18 | Formulation and analysis of a three-dimensional finite element implementation for adhesive contact at nanoscale显示文摘 | Roger A Sauer Peter Wriggers | 2009 | Computer Methods in Applied Mechanics and Engieering2009，198，49505152： | 1 |
| 19 | Oxygen isotope ratios of organic matter in arctic lakes as a paleoclimate proxy: field and laboratory investigations显示文摘 | Peter E. Sauer Gifford H. Miller Jonathan T. Overpeck | 2001 | Journal of Paleolimnology2001，，1： | 1 |
| 20 | Hematopoietic stem cell transplantation for mucopolysaceharidoses and leukodystrophies显示文摘 | Sauer M Grewal S Peters C | 2004 | Klin Padiatr2004，216，3： | 1 |
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