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| 1 | Short-term power load forecasting using integrated methods based on long short-term memory显示文摘The development of power system informatization,the massive access of distributed power supply and electric vehicles have increased the complexity of power consumption in the distribution network,which puts forward higher requirements for the accuracy and stability of load forecasting.In this paper,an integrated network architecture which consists of the self-organized mapping,chaotic time series,intelligent optimization algorithm and long short-term memory(LSTM)is proposed to extend the load forecasting length,decrease artificial debugging,and improve the prediction precision for the short-term power load forecasting.Compared with LSTM prediction,the algorithm in this paper improves the prediction accuracy by 61.87%in terms of root mean square error(RMSE),and reduces the prediction error by 50%in the 40-fold forecast window under some circumstances. | ZHANG WenJie QIN Jian MEI Feng FU JunJie DAI Bo YU WenWu | 2020 | Science China(Technological Sciences)2020，63，4： | 7 |
| 2 | Sediment transportation and bed morphology reshaping in Yellow River Delta显示文摘The Yellow River Delta supports the ecological function as a typical estuarine foreshore wetland. The wetland area is changing greatly every year because of sediment deposition and erosion, which influences the wetland function tremendously. Application of environmental fluid dynamics code (EFDC) to the Yellow River Delta is on the basis of the mobile bed dynamic model and wetting-drying process. Careful calibration is carried out for the numerical model which is set up for the Yellow River Delta, the sediment transport process of the model is compatible to the Yellow River situation. The simulated bed elevation by considering the sediment deposition in the Mouth is particularly focused on, the numerical results are in agreement with the measured bed morphology within 1992 2000. Simulation in this paper indicates that most of the sediment deposited just out of the Mouth which makes the mouth move forward into the sea 2.5 km per year. This paper presents good results in simulation of varying sediment deposition and provides further methods to predict the future morphology and area of the Yellow River Delta. | KONG QingRong JIANG ChunBo QIN JunJie GUO Bin | 2009 | Science China(Technological Sciences)2009，52，11： | 6 |
| 3 | Effect of Linguizhugan decoction on hyperlipidemia rats with intermittent fasting显示文摘OBJECTIVE:To explore the effect of Linguizhugan decoction on hyperlipidemia rats with caloric restriction.METHODS:The hyperlipidemia model of rat was induced by high fat diet for 8 weeks.After the model was established,26 rats were randomly divided into 4 groups:the control group(n=6),the model group(n=6),the intermittent fasting(IF) group(n= 8),and the IF and herbal medicine(IFH) group(n= 6).IF group was applied intermittent fasting every other day.The IFH group was given Linguizhugan decoction every day and intermittent fasting every other day.Blood samples were taken at the end of 16 weeks,and serum ghrelin and lipid was tested.RESULTS:Serum ghrelin in the IF group significantly increased(P<0.01).Serum ghrelin in IFH group was lower than the IF group(P<0.05),but higher than the model group(P<0.01).CONCLUSION:Linguizhugan decoction may play a part in regulation of energy and appetite in hyperlipidemia rats with IF. | Yubin Yang Jian Qin Bin Ke Junjie Zhang Lanying Shi Qiong Li | 2013 | Journal of Traditional Chinese Medicine2013，33，2： | 6 |
| 4 | Loss of Gn1a/OsCKX2 confers heavy-panicle rice with excellent lodging resistance显示文摘Significant achievements have been made in breeding programs for the heavy-panicle-type(HPT)rice(Oryza sativa) in Southwest China. The HPT varieties now exhibit excellent lodging resistance,allowing them to overcome the greater pressures caused by heavy panicles. However, the genetic mechanism of this lodging resistance remains elusive. Here, we isolated a major quantitative trait locus, Panicle Neck Diameter 1(PND1), andidentified the causal gene as GRAIN NUMBER 1 A/CYTOKININ OXIDASE 2(Gn1 A/Os CKX2). The null gn1 a allele from rice line R498(gn1 aR498) improved lodging resistance through increasing the culm diameter and promoting crown root development.Loss-of-function of Gn1 a/Os CKX2 led to cytokinin accumulation in the crown root tip and accelerated the development of adventitious roots. Gene pyramiding between the null gn1 aR498 allele with two gain-of-function alleles, STRONG CULM 2(SCM2)and SCM3, further improved lodging resistance.Moreover, Gn1 a/Os CKX2 had minimal influence on overall rice quality. Our research thus highlights the distinct genetic components of lodging resistance of HPT varieties and provides a strategy for tailormade crop improvement of both yield and lodging resistance in rice. | Bin Tu Zhang Tao Shiguang Wang Lei Zhou Ling Zheng Chun Zhang Xinzi Li Xiaoyu Zhang Junjie Yin Xiaobo Zhu Hua Yuan Ting Li Weilan Chen Peng Qin Bingtian Ma Yuping Wang Shigui Li | 2022 | Journal of Integrative Plant Biology2022，64，1： | 5 |
| 5 | ScCas9 recognizes NNG protospacer adjacent motif in genome editing of rice显示文摘The CRISPR/Cas(clustered regularly in terspaced short palindromic repeats/CRISPR-associated protein)system has been widely used in genome editing,epigenetic modification,and other applications,because it is a precise,inexpensive,powerful and easy-to?use editing tool(Zhang et al.,2019).However,the scope of genome editing is limited by a short protospacer adjacent motif(PAM)specific sequence flanking the target site.Streptococcus pyogenes Cas9(5^Cas9),the most widely used Cas,strongly recognizes NGG PAM and partially recognizes NAG PAM in rice and is restricted to target the sites with these motifs(Anders et al.,2014;Meng et al.,2018). | Yibo Xu Xiangbing Meng Junjie Wang Baoxiang Qin Kejian Wang Jiayang Li Chun Wang Hong Yu | 2020 | Science China(Life Sciences)2020，63，3： | 4 |
| 6 | Signatures within esophageal microbiota with progression of esophageal squamous cell carcinoma显示文摘Objective: Esophageal squamous cell carcinoma(ESCC) is one of the dominant malignances worldwide, but currently there is less focus on the microbiota with ESCC and its precancerous lesions.Methods: Paired esophageal biopsy and swab specimens were obtained from 236 participants in Linzhou, China.Data from 16 S ribosomal RNA gene sequencing were processed using quantitative insights into microbial ecology(QIIME2) and R Studio to evaluate differences. The Wilcoxon rank sum test and Kruskal-Wallis rank sum test were used to compare diversity and characteristic genera by specimens and participant groups. Ordinal logistic regression model was used to build microbiol prediction model.Results: Microbial diversity was similar between biopsy and swab specimens, including operational taxonomic unit(OTU) numbers and Shannon index. There were variations and similarities of esophageal microbiota among different pathological characteristics of ESCC. Top 10 relative abundance genera in all groups include Streptococcus, Prevotella, Veillonella, Actinobacillus, Haemophilus, Neisseria, Alloprevotella, Rothia, Gemella and Porphyromonas. Genus Streptococcus, Haemophilus, Neisseria and Porphyromonas showed significantly difference in disease groups when compared to normal control, whereas Streptococcus showed an increasing tendency with the progression of ESCC and others showed a decreasing tendency. About models based on all combinations of characteristic genera, only taken Streptococcus and Neisseria into model, the prediction performance was the ideal one, of which the area under the curve(AUC) was 0.738.Conclusions: Esophageal biopsy and swab specimens could yield similar microbial characterization. The combination of Streptococcus and Neisseria has the potential to predict the progression of ESCC, which is needed to confirm by large-scale, prospective cohort studies. | Minjuan Li Dantong Shao Jiachen Zhou Jianhua Gu Junjie Qin Wen Chen Wenqiang Wei | 2020 | Chinese Journal of Cancer Research2020，32，6： | 4 |
| 7 | Double lock of a potent human therapeutic monoclonal antibody against SARS-CoV-2显示文摘Receptor recognition and subsequent membrane fusion are essential for the establishment of successful infection by SARS-CoV-2.Halting these steps can cure COVID-19.Here we have identified and characterized a potent human monoclonal antibody,HB27,that blocks SARS-CoV-2 attachment to its cellular receptor at sub-nM concentrations.Remarkably,HB27 can also prevent SARS-CoV-2 membrane fusion.Consequently,a single dose of HB27 conferred effective protection against SARS-CoV-2 in two established mouse models.Rhesus macaques showed no obvious adverse events when administrated with10 times the effective dose of HB27.Cryo-EM studies on complex of SARS-CoV-2 trimeric S with HB27 Fab reveal that three Fab fragments work synergistically to occlude SARS-CoV-2 from binding to the ACE2 receptor.Binding of the antibody also restrains any further conformational changes of the receptor binding domain,possibly interfering with progression from the prefusion to the postfusion stage.These results suggest that HB27 is a promising candidate for immuno-therapies against COVID-19. | Ling Zhu Yong-Qiang Deng Rong-Rong Zhang Zhen Cui Chun-Yun Sun Chang-Fa Fan Xiaorui Xing Weijin Huang Qi Chen Na-Na Zhang Qing Ye Tian-Shu Cao Nan Wang Lei Wang Lei Cao Huiyu Wang Desheng Kong Juan Ma Chunxia Luo Yanjing Zhang Jianhui Nie Yao Sun Zhe Lv Neil Shaw Qianqian Li Xiao-Feng Li Junjie Hu Liangzhi Xie Zihe Rao Youchun Wang Xiangxi Wang Cheng-Feng Qin | 2021 | National Science Review2021，8，3： | 3 |
| 8 | Long-term clinical observation of patients with acute and chronic complete spinal cord injury after transplantation of Neuro Regen scaffold显示文摘Spinal cord injury(SCI)often results in an inhibitory environment at the injury site.In our previous studies,transplantation of a scaffold combined with stem cells was proven to induce neural regeneration in animal models of complete SCI.Based on these preclinical studies,collagen scaffolds loaded with the patients’own bone marrow mononuclear cells or human umbilical cord mesenchymal stem cells were transplanted into SCI patients.Fifteen patients with acute complete SCI and 51 patients with chronic complete SCI were enrolled and followed up for 2 to 5 years.No serious adverse events related to functional scaffold transplantation were observed.Among the patients with acute SCI,five patients achieved expansion of their sensory positions and six patients recovered sensation in the bowel or bladder.Additionally,four patients regained voluntary walking ability accompanied by reconnection of neural signal transduction.Among patients with chronic SCI,16 patients achieved expansion of their sensation level and 30 patients experienced enhanced reflexive defecation sensation or increased skin sweating below the injury site.Nearly half of the patients with chronic cervical SCI developed enhanced finger activity.These long-term follow-up results suggest that functional scaffold transplantation may represent a feasible treatment for patients with complete SCI. | Fengwu Tang Jiaguang Tang Yannan Zhao Jiaojiao Zhang Zhifeng Xiao Bing Chen Guang Han Na Yin Xianfeng Jiang Changyu Zhao Shixiang Cheng Ziqiang Wang Yumei Chen Qiaoling Chen Keran Song Zhiwei Zhang Junjie Niu Lingjun Wang Qin Shi Liang Chen Huilin Yang Shuxun Hou Sai Zhang Jianwu Dai | 2022 | Science China(Life Sciences)2022，65，5： | 3 |
| 9 | Origin and circulation of saline springs in the Kuqa Basin of the Tarim Basin,Northwest China显示文摘It is widely accepted that hydrogeochemistry of saline springs is extremely important to understand the water circulation and evolution of saline basins and to evaluate the potential of potassium-rich evaporites.The Kuqa Basin,located in the northern part of the Tarim Basin in Northwest China,is a saline basin regarded as the most potential potash-seeking area.However,the origin and water circulation processes of saline springs have yet to be fully characterized in this saline basin.In this study,a total of 30 saline spring samples and 11 river water samples were collected from the Qiulitage Structural Belt(QSB)of the Kuqa Basin.They were analyzed for major(K^+,Ca2^+,Na^+,Mg2^+,SO42-,Cl-and HCO3-)and trace(Sr2^+and Br-)ion concentrations,stable H-O-Sr isotopes and tritium concentrations in combination with previously published hydrogeochemical and isotopic(H-O)data in the same area.It is found that the water chemical type of saline springs in the study area belonged to the Na-Cl type,and that of river water belonged to the Ca-Mg-HCO3-SO4 type.The total dissolved solid(TDS)of saline springs in the QSB ranged from 117.77 to 314.92 g/L,reaching the brine level.On the basis of the general chemical compositions and the characteristics of the stable H-O-Sr isotopes of saline springs,we infer that those saline springs mainly originated from precipitation following river water recharging.In addition,we found that saline springs were not formed by evapo-concentration because it is unlikely that the high chloride concentration of saline springs resulted in evapo-concentration and high salinity.Therefore,we conclude that saline spring water may have experienced intense evapo-concentration before dissolving the salty minerals or after returning to the surface.The results show that the origin of salinity was mainly dominated by dissolving salty minerals due to the river water and/or precipitation that passed through the halite-rich stratum.Moreover,there are two possible origins of saline springs in the QSB:one is the infiltration of the meteoric water(river water),which then circulates deep into the earth,wherein it dissolves salty minerals,travels along the fault and returns to the surface;another is the mixture of formation water,or the mixture of seawater or marine evaporate sources and its subsequent discharge to the surface under fault conditions.Our findings provide new insight into the possible saltwater circulation and evolution of saline basins in the Tarim Basin. | SHAN Junjie WANG Jianping SHAN Fashou TENG Xueming FAN Qishun LIQingkuan QIN Zhanjie ZHANG Xiangru | 2020 | Journal of Arid Land2020，12，2： | 2 |
| 10 | Zn-based metal organic framework derivative with uniform metal sites and hierarchical pores for efficient adsorption of formaldehyde显示文摘A Zn-containing graphite carbon(Zn-GC)with uniform Zn metal sites and hierarchical pore structure was obtained by pyrolysis of Zn-based metal organic framework(MOF).Zn-GC exhibited excellent adsorption capacity and reproducibility for formaldehyde.The adsorption capacity of Zn-GC was 736 times that of commercial activated carbon and 5.6 times that of ZSM-5 adsorbents.The characterization and experimental results showed that the surface chemical characteristics of the adsorption material play an important role in the adsorption performance.The superior performance was attributed to Zn metal sites and oxygen-containing functional groups on the MOF derivative as well as hierarchical pore structure.The material showed a great potential in the field of organic pollutant removal. | Junjie Yang Junxian Qin Ziyang Guo Yun Hu Xia Zhang | 2021 | Chinese Chemical Letters2021，32，5： | 2 |
| 11 | Is oral microbiome of children able to maintain resistance and functional stability in response to short-term interference of ingesta?显示文摘Dear Editor,A series of studies had focused on the ecological stability of human microbiome(Lozupone et al.,2012;Faith et al.,2013;Moya and Ferrer,2016).Despite the continuous perturbation and the highly personalized composition within the human microbiome(Human Microbiome Project,2012),healthy adults stably maintain their microbial communities in terms of space and time(Faith et al.,2013;Moya and Ferrer,2016;Oh et al.,2016).This stability is proved to be critical for the well-being of human body(Lozupone et al.,2012).On the contrary,major shifts in microbial community composition are often related to diseases(Lynch and Pedersen,2016). | Fangqiao Wei Xiangyu Sun Yufeng Gao Haoyu Dou Yang Liu Lili Su Haofei Luo Ce Zhu Qian Zhang Peiyuan Tong Wen Ren Zhe Xun Ruochun Guo Yuanlin Guan Shenghui Li Yijun Qi Junjie Qin Feng Chen Shuguo Zheng | 2021 | Protein & Cell2021，12，6： | 1 |
| 12 | Metagenome-wide analysis of antibiotic resistance genes in a large cohort of human gut microbiota显示文摘 | HU Yongfei YANG Xi QIN Junjie | 2013 | Nature Communications2013，4，： | 1 |
| 13 | A human gut microbial gene catalogue established by metagenomic sequencing显示文摘 | Junjie Qin Ruiqiang Li Jeroen Raes | 2010 | Nature2010，464，7285： | 1 |
| 14 | An InDel-based linkage map of hot pepper ( Capsicum annuum )显示文摘 | Weipeng Li Jiaowen Cheng Zhiming Wu Cheng Qin Shu Tan Xin Tang Junjie Cui Li Zhang Kailin Hu | 2015 | Molecular Breeding2015，，1： | 1 |
| 15 | Effect of Sand Body Enrichment Under the Restriction of a Tectonic Transfer Zone: A Case Study on the Pinghu Formation in the Kongqueting Region on the Pinghu Slope显示文摘Results of long-term explorations in the Kongqueting region,located in an East China Sea depression,suggest that the strong fault activity during the sedimentary period of the Pinghu formation significantly influenced the development of the sedimentary system.However,the aggregation and enrichment of the sand body under a tectonic background has become a problem that requires an immediate solution.Considering research outcomes of previous studies,this study used three-dimensional seismic and logging data to identify Y-or H-type and the en echelon distribution patterns of the fault plane,as well as identify the locations wherein the fault growth index value is greater than 1 in the study region,indicating the tectonic background of the fault transfer zone in the region.Second,the development type of the fault transfer zone was studied,and the sand body enrichment site was identified based on seismic inversion data and the development position of the fault transfer point.This helps clarify the evolution of sedimentary facies of the Pinghu formation combined with the sedimentary environment of the braided-river delta.Finally,after summarizing the coupling relationship between the synsedimentary fault systems and the sand body enrichment patterns,three sand-control models were determined,namely,the flexural-parallel,the en echelon collinear,and the torsional-reformed superimposed transfer zones.The findings of this study lay a foundation for the subsequent search of tectonic lithologic oil and gas reservoirs. | LI Junjie HOU Guowei QIN Lanzhi XIE Jingjing JIANG Xue | 2021 | Journal of Ocean University of China2021，20，4： | 1 |
| 16 | 3D-printed NIR-responsive shape memory polyurethane/magnesium scaffolds with tight-contact for robust bone regeneration显示文摘Patients with bone defects suffer from a high rate of disability and deformity.Poor contact of grafts with defective bones and insufficient osteogenic activities lead to increased loose risks and unsatisfied repair efficacy.Although self-expanding scaffolds were developed to enhance bone integration,the limitations on the high transition temperature and the unsatisfied bioactivity hindered greatly their clinical application.Herein,we report a near-infrared-responsive and tight-contacting scaffold that comprises of shape memory polyurethane(SMPU)as the thermal-responsive matrix and magnesium(Mg)as the photothermal and bioactive component,which fabricated by the low temperature rapid prototyping(LT-RP)3D printing technology.As designed,due to synergistic effects of the components and the fabrication approach,the composite scaffold possesses a homogeneously porous structure,significantly improved mechanical properties and stable photothermal effects.The programmed scaffold can be heated to recover under near infrared irradiation in 60s.With 4 wt%Mg,the scaffold has the balanced shape fixity ratio of 93.6%and shape recovery ratio of 95.4%.The compressed composite scaffold could lift a 100 g weight under NIR light,which was more than 1700 times of its own weight.The results of the push-out tests and the finite element analysis(FEA)confirmed the tight-contacting ability of the SMPU/4 wt%Mg scaffold,which had a signficant enhancement compared to the scaffold without shape memory effects.Furthermore,The osteopromotive function of the scaffold has been demonstrated through a series of in vitro and in vivo studies.We envision this scaffold can be a clinically effective strategy for robust bone regeneration. | Yuanchi Zhang Cairong Li Wei Zhang Junjie Deng Yangyi Nie Xiangfu Du Ling Qin Yuxiao Lai | 2022 | Bioactive Materials2022，7，10： | 1 |
| 17 | A human gut microbial genecatalogue established by metagenomic sequencing显示文摘 | QIN Junjie LI Ruiqiang RAES J | 2010 | Nature2010，464，： | 1 |
| 18 | Coordinated attitude control for flexible spacecraft formation with actuator configuration misalignment显示文摘This paper investigates the coordinated attitude control problem for flexible spacecraft formation with the consideration of actuator configuration misalignment.First,an integral-type sliding mode adaptive control law is designed to compensate the effects of flexible mode,environmental disturbance and actuator installation deviation.The basic idea of the Integral-type Sliding Mode Control(ISMC)is to design a proper sliding manifold so that the sliding mode starts from the initial time instant,and thus the robustness of the system can be guaranteed from the beginning of the process and the reaching phase is eliminated.Then,considering the nominal system of spacecraft formation based on directed topology,an attitude cooperative control strategy is developed for the nominal system with or without communication delay.The proposed control law can guarantee that for each spacecraft in the spacecraft formation,the desired attitude objective can be achieved and the attitude synchronization can be maintained with other spacecraft in the formation.Finally,simulation results are given to show the effectiveness of the proposed control algorithm. | Xiaomei CHENG Yuan LIU Yi QIN Feng WANG Junjie ZHANG | 2021 | Chinese Journal of Aeronautics2021，34，3： | 1 |
| 19 | Triterpenoid glycosides from leaves of llex conuta显示文摘 | Qin Wenjuan Wu Xiue Zhao Junjie | 1986 | Phytochemistry1986，25，4： | 1 |
| 20 | C-Reactive Protein and Complement Components in Patients with Pathological Myopia显示文摘 | Qin Long Junjie Ye Ying Li Shuran Wang Yang Jiang | 2013 | Optometry and Vision Science2013，，5： | 1 |
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