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| 1 | Particulate matter pollution in Kunshan High-Tech zone: Source apportionment with trace elements, plume evolution and its monitoring显示文摘Particulate matter(PM) in the Kunshan High-Tech zone is studied during a three-month campaign. PM and trace elements are measured by the online pollution monitoring, forecastwarning and source term retrieval system AS3. Hourly measured concentrations of PM_(10), PM_(2.5) and 16 trace elements in the PM_(2.5) section(Ca, Pb, Cu, Cl, V, Cr, Fe, Ti, Mn, Ni, Zn, Ga, As, Se, Sr, Ba)are focused. Source apportionment of trace elements by Positive Matrix Factorization modeling indicates that there are five major sources, including dust, industrial processing, traffic,combustion, and sea salt with contribution rate of 23.68%, 21.66%, 14.30%, 22.03%, and 6.89%,respectively. Prediction of plume dispersion from concrete plant and traffic emissions shows that PM_(10) pollution of concrete plant is three orders of magnitude more than that of the traffic. The influence range can extend to more than 3 km in 1 hr. Because the footprint of the industrial plumes is constantly moving according to the local meteorological conditions, the fixed monitoring sites scattered in a few hundred meters haven't captured the heaviest pollution plume at the local scale of a few km^2. As a more intensive monitoring network is not operationally possible, the use of online modeling gives accurate and quantitative information of plume location, which increases the spatial pollution monitoring capacity and improves the understanding of measurement data. These results indicate that the development of the AS3 system, which combines monitoring equipment and air pollution modeling systems, is beneficial to the real-time pollution monitoring in the industrial zone. | Suwei Zhang Qijie Zhang Armand Albergel Didier Buty Liangmin Yu Haiting Wang Wuxia Bi Peng Cheng Fu Chen Jun Fang Ruirui Hou Xudong Luan Changgan Shu Jingjing Su | 2018 | Journal of Environmental Sciences2018，30，9： | 3 |
| 2 | Baeyer-Villiger Oxidation of Cyclic Ketones Catalyzed by Amino Acid Ionic Liquids显示文摘A series of amino-acid-based ionic liquids was synthesized via one-step protonation of the corresponding L-amiiio acid by utilizing an array of proton sources.The catalytic activity of the amino-acid-based ionic liquids for the Baeyer-Villiger oxidation of cyclic ketones was investigated using cyclopentanone as a model cycloketone.Theproline-based ionic liquid[ProH]CF3SO3 was shown to exliibit thebest catalytic activity.The reaction condition was optimized to give the following reagent ratio of h(cyclopentanone):n(catalyst):w(H2O2)=1:0.06:4,60℃and 6 h.Under the optimum conditions,the conversion of cyclopentanone was 96.57%and the selectivity forδ-valerolactone was 73.01%.The catalytic activity was shown to be constant after 4 cycles.A simple treatment was allowed for the recover and the reuse of[ProH]CF3S03.The successful utilization of[ProH]CF3SO3 to catalyze a host of cyclic ketones via Baeyer-Villiger oxidation clearly demonstrated the capacity of[ProH]CF3S03 to tolerate variation in the substrate. | YU Fengli CHI Yujie GAO Chong CHEN Ruirui XIE Congxia YU Shitao | 2020 | Chemical Research in Chinese Universities2020，36，5： | 1 |
| 3 | The C_(6)D_(6)detector system on the Back-n beam line of CSNS显示文摘Introduction The neutron capture cross sections are very important in the field of nuclear device design and basic physics research.Hydrogen-free liquid scintillator such as C_(6)D_(6)detectors are widely used in the neutron capture cross-sectional measurements for the low neutron sensitivity and fast time response.The Back-n white neutron source at China Spallation Neutron Source is the first spallation white neutron source in China,and it is suitable for neutron capture cross-sectional measurement.Materials and methods A C_(6)D_(6)detector system was built in the Back-n experimental station.The pulse height weighting technique was used to determine the system’s detection efficiency.The response to gamma rays of the C_(6)D_(6)detector was measured,and the energy resolution function was determined.Monte Carlo simulation with Geant4 code was carried out to get the weighting function of this C_(6)D_(6)detector system.Additionally,the systematic uncertainty of the weighting function was also determined.Conclusion According to the experimental and simulation results,this C_(6)D_(6)detector system can be used to measure neutron capture cross section. | Jie Ren Xichao Ruan Jie Bao Guangyuan Luan Wei Jiang Qi An Huaiyong Bai Ping Cao Qiping Chen Yonghao Chen Pinjing Cheng Zengqi Cui Ruirui Fan Changqing Feng Minhao Gu Fengqin Guo Changcai Han Zijie Han Guozhu He Yongcheng He Yuefeng He Hanxiong Huang Weiling Huang Xiru Huang Xiaolu Ji Xuyang Ji Haoyu Jiang Hantao Jing Ling Kang Mingtao Kang Bo Li Lun Li Qiang Li Xiao Li Yang Li Yang Li Rong Liu Shubin Liu Xingyan Liu Yinglin Ma Changjun Ning Binbin Qi Zhaohui Song Hong Sun Xiaoyang Sun Zhijia Sun Zhixin Tan Hongqing Tang Jingyu Tang Pengcheng Wang Qi Wang Taofeng Wang Yanfeng Wang Zhaohui Wang Zheng Wang Jie Wen Zhongwei Wen Qingbiao Wu Xiaoguang Wu Xuan Wu Likun Xie Yiwei Yang Han Yi Li Yu Tao Yu Yongji Yu Guohui Zhang Jing Zhang Linhao Zhang Liying Zhang Qingmin Zhang Qiwei Zhang Xianpeng Zhang Yuliang Zhang Zhiyong Zhang Yingtan Zhao Liang Zhou Zuying Zhou Danyang Zhu Kejun Zhu Peng Zhu | 2019 | Radiation Detection Technology and Methods2019，3，3： | 1 |
| 4 | Nitric oxide participates in the regulation of LeCBF1 gene expression and improves cold tolerance in harvested tomato fruit显示文摘 | Ruirui Zhao Jiping Sheng Shengnan Lv Yang Zheng Jian Zhang Mengmeng Yu Lin Shen | 2011 | Postharvest Biology and Technology2011，，2： | 1 |
| 5 | Nitric oxide participates in the regulation of LeCBF1 gene expression and improves cold tolerance in harvested tomato fruit显示文摘 | Ruirui Zhao Jiping Sheng Shengnan Lv Yang Zheng Jian Zhang Mengmeng Yu Lin Shen | 2011 | Postharvest Biology and Technology2011，，： | 1 |
| 6 | Cell-delivery therapeutics for liver regeneration显示文摘 | Wenxia Zhang Lisa Tucker-Kellogg B.C. Narmada Lakshmi Venkatraman Shi Chang Yin Lu Nancy Tan Jacob K. White Ruirui Jia Sourav Saha Bhowmick Shali Shen C. Forbes Dewey Hanry Yu | 2010 | Advanced Drug Delivery Reviews2010，，7： | 1 |
| 7 | Exposure Response Relationship of Acute Effects of Air Pollution on Respiratory Diseases-China,2013−2018显示文摘Summary What is already known about this topic?Short-term exposure to air pollutants has been associated with chronic obstructive pulmonary disease(COPD)and asthma,which needs continuous observation.What is added by this report?This study uses the longest time series data so far from 2013 to 2018 and adds additional data analysis for ozone(O_(3))to existing studies. | Hongtao Niu Tao Yu Xuexin Li Hanna Wu Meilin Yan Ruirui Duan Ting Yang | 2021 | China CDC weekly2021，3，45： | 1 |
| 8 | DOCK2 regulates antifungal immunity by regulating RAC GTPase activity显示文摘Fungal infections cause~1.5 million deaths each year worldwide,and the mortality rate of disseminated candidiasis currently exceeds that of breast cancer and malaria.The major reasons for the high mortality of candidiasis are the limited number of antifungal drugs and the emergence of drug-resistant species.Therefore,a better understanding of antifungal host defense mechanisms is crucial for the development of effective preventive and therapeutic strategies.Here,we report that DOCK2(dedicator of cytokinesis 2)promotes indispensable antifungal innate immune signaling and proinflammatory gene expression in macrophages.DOCK2-deficient macrophages exhibit decreased RAC GTPase(Rac family small GTPase)activation and ROS(reactive oxygen species)production,which in turn attenuates the killing of intracellular fungi and the activation of downstream signaling pathways.Mechanistically,after fungal stimulation,activated SYK(spleen-associated tyrosine kinase)phosphorylates DOCK2 at tyrosine 985 and 1405,which promotes the recruitment and activation of RAC GTPases and then increases ROS production and downstream signaling activation.Importantly,nanoparticle-mediated delivery of in vitro transcribed(IVT)Rac1 mRNA promotes the activity of Rac1 and helps to eliminate fungal infection in vivo.Taken together,this study not only identifies a critical role of DOCK2 in antifungal immunity via regulation of RAC GTPase activity but also provides proof of concept for the treatment of invasive fungal infections by using IVT mRNA. | Xiaojian Ma Xi Tan Bingbing Yu Wanwei Sun Heping Wang Huijun Hu Yanyun Du Ruirui He Ru Gao Qianwen Peng Zhihui Cui Ting Pan Xiong Feng Junhan Wang Chengqi Xu Bin Zhu Wei Liu Chenhui Wang | 2022 | Cellular & Molecular Immunology2022，19，5： | 1 |
| 9 | Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia显示文摘Aberrant self-renewal of leukemia initiation cells(LICs)drives aggressive acute myeloid leukemia(AML).Here,we report that UHRF1,an epigenetic regulator that recruits DNMT1 to methylate DNA,is highly expressed in AML and predicts poor prognosis.UHRF1 is required for myeloid leukemogenesis by maintaining self-renewal of LICs.Mechanistically,UHRF1 directly interacts with Sin3A-associated protein 30(SAP30)through two critical amino acids,G572 and F573 in its SRA domain,to repress gene expression.Depletion of UHRF1 or SAP30 derepresses an important target gene,MXD4,which encodes a MYC antagonist,and leads to suppression of leukemogenesis.Further knockdown of MXD4 can rescue the leukemogenesis by activating the MYC pathway.Lastly,we identified a UHRF1 inhibitor,UF146,and demonstrated its significant therapeutic efficacy in the myeloid leukemia PDX model.Taken together,our study reveals the mechanisms for altered epigenetic programs in AML and provides a promising targeted therapeutic strategy against AML. | Cheng-Long Hu Bing-Yi Chen Zijuan Li Tianbiao Yang Chun-Hui Xu Ruirui Yang Peng-Cheng Yu Jingyao Zhao Ting Liu Na Liu Bin Shan Qunling Zhang Junhong Song Ming-Yue Fei Li-Juan Zong Jia-Ying Zhang Ji-Chuan Wu Shu-Bei Chen Yong Wang Binhe Chang Dan Hou Ping Liu Yilun Jiang Xiya Li Xinchi Chen Chu-Han Deng Yi-Yi Ren Roujia Wang Jiacheng Jin Kai Xue Ying Zhang Meirong Du Jun Shi Ling-Yun Wu Chun-Kang Chang Shuhong Shen Zhu Chen Sai-Juan Chen Xiaolong Liu Xiao-Jian Sun Mingyue Zheng Lan Wang | 2022 | Cell Research2022，32，12： | 1 |
| 10 | The physicochemical properties of different biomass ashes at different ashing temperature显示文摘 | Ruirui Xiao Xueli Chen Fuchen Wang Guangsuo Yu | 2010 | Renewable Energy2010，，1： | 1 |
| 11 | 3D magnetic field guided sunflower-like nanocatalytic active swarm targeting patients-derived organoids显示文摘Nanocatalytic medicine triggering in situ catalytic reactions has been considered as a promising strategy for tumor-selective therapeutics.However,the targeted distribution of nanocatalysts was still low,considering the absence of targeting propulsion capability.Here,encouraged by the fast-developing controllable microrobotics for targeting delivery,a sunflower-like nanocatalytic active swarm(SNCAS)controlled by a three-dimensional(3D)magnetic field was proposed for synergistic tumorselective and magnetic-actively tumor-targeting therapeutics.Furthermore,a patient-derived renal cancer cell 3D organoid was utilized for the verification of the effective tumor therapeutic outcomes.Under the targeted control of 3D magnetic field,the multiple cascade catalytic efficiency of SNCAS based on Fenton reaction was evaluated,resulting in efficient tumor cell apoptosis and death.For the patient-derived organoid treatment,the SNCAS presented significant lethality toward 3D organoid structure to induce cell apoptosis with the collapse of organoid morphology.The targeting efficiency was further enhanced under the magnetic-controllable of SNCAS.Overall,empowered by the magnetic control technology,the synergistic therapeutic strategy based on controllable swarm combined active targeting and tumor-specific catalytic nanomedicine has provided a novel way for advanced cancer therapy.Meanwhile,3D patient-derived organoids were proved as a powerful tool for the effectiveness verification of nanocatalytic medicine. | Dong Liu Ruirui Guo Shuangshuang Mao Yanjie Huang Bin Wang Zijian Wu Xuanjie Xia Jian Dong Yu Xin Ruiyang Xie Jianzhong Shou Wei Sun Yuan Pang Yuan Lu | 2023 | Nano Research2023，16，1： | 0 |
| 12 | Detector development at the Back-n white neutron source显示文摘Purpose Back-n is a white neutron beamline at China spallation neutron source,which was established in the year of 2018.It is a powerful facility for nuclear data measurement,neutron detector calibration,and radiation effect research.Method A series of detectors were built for different experiments,including beam monitoring,beam profile measurement,neutron induced secondaries(fission fragments,light charged particles and gamma)cross section measurement,and neutron resonance radiography,etc.A common digitization electronics and a cluster-based DAQ were developed for these detector systems.Most detectors have been employed at Back-n and serviced for experiments from the beginning of the beamline running.Results and conclusion As an overview of detectors of Back-n,the details of the detector design and the experiment performing are described in this paper.Some developing systems,e.g.,MTPC and B-MCP,are also included. | Fan Ruirui Li Qiang Bao Jie Li Yang Liu Rong Jiang Wei Ren Jie Zhang Qiwei Cao Ping Gu Minhao Ren Zhizhou Yi Han Tang Jingyu An Qi Bai Haofan Bai Jiangbo Chen Qiping Chen Yonghao Chen Zhen Cui Zengqi Fan Anchuan Feng Changqing Feng Fanzhen Gao Keqing Han Changcai Han Zijie He Guozhu He Yongcheng Hong Yang Hu Yiwei Huang Hanxiong Jia Weihua Jiang Haoyu Jiang Zhijie Jin Zhengyao Kang Ling Li Bo Li Chao Li Gong Li Jiawen Li Xiao Liu Jie Liu Shubin Luan Guangyuan Ning Changjun Qi Binbin Ruan Xichao Song Zhaohui Sun Kang Tan Zhixin Tang Shengda Wang Pengcheng Wang Zhaohui Wen Zhongwei Wu Xiaoguang Wu Xuan Xie Likun Yang Yiwei Yu Yongji Zhang Guohui Zhang Linhao Zhang Mohan Zhang Xianpeng Zhang Yuliang Zhang Yue Zhang Zhiyong Zhao Maoyuan Zhou Luping Zhou Zhihao Zhu Kejun The CSNS Back-n Collaboration | 2023 | Radiation Detection Technology and Methods2023，7，2： | 0 |
| 13 | Cardiopulmonary prognosis of prophylactic endotracheal intubation in patients with upper gastrointestinal bleeding undergoing endoscopy显示文摘BACKGROUND:It is controversial whether prophylactic endotracheal intubation(PEI)protects the airway before endoscopy in critically ill patients with upper gastrointestinal bleeding(UGIB).The study aimed to explore the predictive value of PEI for cardiopulmonary outcomes and identify high-risk patients with UGIB undergoing endoscopy.METHODS:Patients undergoing endoscopy for UGIB were retrospectively enrolled in the eICU Collaborative Research Database(eICU-CRD).The composite cardiopulmonary outcomes included aspiration,pneumonia,pulmonary edema,shock or hypotension,cardiac arrest,myocardial infarction,and arrhythmia.The incidence of cardiopulmonary outcomes within 48 h after endoscopy was compared between the PEI and non-PEI groups.Logistic regression analyses and propensity score matching analyses were performed to estimate effects of PEI on cardiopulmonary outcomes.Moreover,restricted cubic spline plots were used to assess for any threshold effects in the association between baseline variables and risk of cardiopulmonary outcomes(yes/no)in the PEI group.RESULTS:A total of 946 patients were divided into the PEI group(108/946,11.4%)and the non-PEI group(838/946,88.6%).After propensity score matching,the PEI group(n=50)had a higher incidence of cardiopulmonary outcomes(58.0%vs.30.3%,P=0.001).PEI was a risk factor for cardiopulmonary outcomes after adjusting for confounders(odds ratio[OR]3.176,95%confidence interval[95%CI]1.567-6.438,P=0.001).The subgroup analysis indicated the similar results.A shock index>0.77 was a predictor for cardiopulmonary outcomes in patients undergoing PEI(P=0.015).The probability of cardiopulmonary outcomes in the PEI group depended on the Charlson Comorbidity Index(OR 1.465,95%CI 1.079-1.989,P=0.014)and shock index>0.77(compared with shock index≤0.77[OR 2.981,95%CI 1.186-7.492,P=0.020,AUC=0.764]).CONCLUSION:PEI may be associated with cardiopulmonary outcomes in elderly and critically ill patients with UGIB undergoing endoscopy.Furthermore,a shock index greater than 0.77 could be used as a predictor of a worse prognosis in patients undergoing PEI. | Yufang Lin Fei’er Song Weiyue Zeng Yichi Han Xiujuan Chen Xuanhui Chen Yu Ouyang Xueke Zhou Guoxiang Zou Ruirui Wang Huixian Li Xin Li | 2023 | World Journal of Emergency Medicine2023，14，5： | 0 |
| 14 | Analysis of Epidemiological and Issues Encountered in Case Reports on Echinococcosis—China,2022显示文摘Summary What is already known about this topic?Echinococcosis is classified as a Class C infectious disease in China.It is endemic in 370 counties located in the agricultural and pastoral regions of western China.What is added by this report?This report provides a comprehensive overview of the cases of echinococcosis reported in China in 2022.Following a thorough evaluation conducted by provincial CDCs. | Yan Kui Shuai Han Xiaojuan Zhang Guangzhong Shi Yale Yu Ruirui Li Peizheng Zhan Hongju Duan Wenbo Luo Benfu Li Shaoqi Ning Yalan Zhang Aiya Zhu Jingbo Xue | 2024 | China CDC weekly2024，6，6： | 0 |
| 15 | Global Avalanche Characteristics of Boolean Functions by Concatenation显示文摘In order to measure the correlation propeties of two Boolean functions,the global avalanche characteristics of Boolean functions constructed by concatenation are discussed,i.e.,f_1‖f_2and f_1‖f_2‖f_3‖f_4.Firstly,for the function f = f_1‖f_2,the cross-correlation function of f_1,f_2 in the special condition are studied.In this case,f,f_1,f_2 must be in desired form.By computing their sum-of-squares indicators,the crosscorrelation function between f_1,f_2 is obtained.Secondly,for the function g = f_1‖f_2‖f_3‖f_4,by analyzing the relation among their auto-correlation functions,their sum-of-squares indicators are investigated.Based on them,the sum-of-squares indicators of functions obtained by Canteaut et al.are investigated.The results show that the correlation property of g is good when the correlation properties of Boolean functions f_1,f_2,f_3,f_4 are good. | Zepeng Zhuo Jinfeng Chong Ruirui Yu Mingsheng Ren | 2016 | Journal of Harbin Institute of Technology(New Series)2016，23，3： | 0 |
| 16 | CsBZIP40 confers resistance against citrus bacterial canker by repressing CsWRKY43-CsPrx53/CsSOD13 cascade mediated ROS scavenging显示文摘As the bacterial etiologic agent causing citrus bacterial canker(CBC),Xanthomonas citri subsp.citri(Xcc)seriously impacts citrus plantation and fruit production globally.In an earlier study,we demonstrated that CsBZIP40 can positively impact CBC resistance in the sweet orange(Citrus sinensis).However,the mechanistic basis for the protective benefits conferred by CsBZIP40 is yet to be delineated.Here,we show that CsBZIP40 positively regulates CBC resistance and reactive oxygen species(ROS)homeostasis in transgenic sweet orange overexpressing CsBZIP40.CsBZIP40 directly binds to the TGA-box of the CsWRKY43 promoter to repress its transcriptional activity.CsWRKY43 overexpression induces CBC susceptibility in transgenic sweet oranges.In contrast,its inhibition produces strong resistance to CBC.CsWRKY43 directly binds to the W-boxes of the CsPrx53 and CsSOD13 promoters to positively regulate the activities of these antioxidant enzymes,resulting in the negative regulation of ROS homeostasis and CBC resistance in sweet orange plants.CsPrx53/CsSOD13 knockdown enhances ROS accumulation and CBC resistance.Overall,our results outline a regulatory pathway through which CsBZIP40 transcriptionally represses CsWRKY43-CsPrx53/CsSOD13 cascade-mediated ROS scavenging in a manner conducive to CBC resistance.These mechanisms underscore the potential importance of CsBZIP40,CsWRKY43,CsPrx53,and CsSOD13,providing promising strategies for the prevention of CBC. | Qiang Li Xiujuan Qin Miao Zhang Qiyuan Yu Ruirui Jia Jie Fan Xin Huang Jia Fu Chenxi Zhang Baohang Xian Wen Yang Qin Long Aihong Peng Lixiao Yao Shanchun Chen Yongrui He | 2023 | Horticulture Research2023，10，8： | 0 |
| 17 | Research progress and application of the CRISPR/Cas9 gene-editing technology based on hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC)is now a common cause of cancer death,with no obvious change in patient survival over the past few years.Although the traditional therapeutic modalities for HCC patients mainly involved in surgery,chemotherapy,and radiotherapy,which have achieved admirable achievements,challenges are still existed,such as drug resistance and toxicity.The emerging gene therapy of clustered regularly interspaced short palindromic repeat/CRISPR-associated nuclease 9-based(CRISPR/Cas9),as an alternative to traditional treatment methods,has attracted considerable attention for eradicating resistant malignant tumors and regulating multiple crucial events of target gene-editing.Recently,advances in CRISPR/Cas9-based anti-drugs are presented at the intersection of science,such as chemistry,materials science,tumor biology,and genetics.In this review,the principle as well as statues of CRISPR/Cas9 technique were introduced first to show its feasibility.Additionally,the emphasis was placed on the applications of CRISPR/Cas9 technology in therapeutic HCC.Further,a broad overview of non-viral delivery systems for the CRISPR/Cas9-based anti-drugs in HCC treatment was summarized to delineate their design,action mechanisms,and anticancer applications.Finally,the limitations and prospects of current studies were also discussed,and we hope to provide comprehensively theoretical basis for the designing of anti-drugs. | Shijing Yu Ruirui Zhao Bingchen Zhang Chunmei Lai Linyan Li Jiangwen Shen Xiarong Tan Jingwei Shao | 2023 | Asian Journal of Pharmaceutical Sciences2023，18，4： | 0 |
| 18 | Arbitrary manipulations of focused higher-order Poincare beams by a Fresnel zone metasurface with alternate binary geometric and propagation phases显示文摘The manipulation of high-quality vector beams(VBs)with metasurfaces is an important topic and has potential for classical and quantum applications.In this paper,we propose a Fresnel zone(FZ)metasurface with metallic nanoslits arranged on FZs,which sets alternate binary geometric and propagation phases to cancel the incident spin component and focus the converted spin component(CSC).The rotation designs of nanoslits transform the incident polarization state on the conventional Poincare sphere to VBs on the higher-order Poincare(HOP)sphere.The two orbital angular momentum states of the CSCs were manipulated,and the focused HOP beams were generated.The experimental results demonstrate the broadband generation of arbitrarily focused HOP beams of high quality under the illumination of the red(632.8 nm),green(532 nm),and blue(473 nm)light.This work will be of significance for the applications of VBs in different areas,such as precision metrology,optical micromanipulation,and quantum information. | XIANGYU ZENG YUQIN ZHANG MANNA GU ZIJUN ZHAN RUIRUI ZHANG YU ZHANG RUI SUN CHANGWEI HE CHUNXIANG LIU CHUANFU CHENG | 2022 | Photonics Research2022，10，4： | 0 |
| 19 | Test of CsI(Tl) Crystal for γ Measurement显示文摘Motivated by measuringγ-rays with CsI crystals, the performance of the CsI(Tl) crystal with the shape as shown in Fig. 1 has been tested. The crystal was grown and machined by IMP crystal group. Firstly, different wrapping materials have been investigated. The tested wrapping materials are Teflon, Tyvek (1056D from Dupont) and ESR (from 3M). During the test, the crystal was | Chen Ruofu, Fan Ruirui, Li Songlin, Xu Hushan, Xu Huagen Sun Zhiyu, Yu Yuhong and Xiao Zhigang | 2005 | 近代物理研究所和兰州重离子加速器实验室年报:英文版2005，，1： | 0 |
| 20 | A novel protein domain is important for photosystem Ⅱ complex assembly and photoautotrophic growth in angiosperms显示文摘Photosystem Ⅱ(PSⅡ)is a multi-subunit protein complex of the photosynthetic electron transport chain that is vital to photosynthesis.Although the structure,composition,and function of PSⅡ have been extensively studied,its biogenesis mechanism remains less understood.Thylakoid rhodanese-like(TROL)provides an anchor for leaf-type ferredoxin:NADP^(+)oxidoreductase.Here,we report the chacterizaton of a second type of TROL protein,TROL2,encoded by seed plant genomes whose function has not previously been reported.We show that TROL2 is a PSⅡ assembly cofactor with essential roles in the establishment of photoautotrophy.TROL2 contains a 45-amino-acid domain,termed the chlorotic lethal seedling(CLS)domain,that is both necessary and sufficient for TROL2 function in PSⅡ assembly and photoautotrophic growth.Phylogenetic analyses suggest that TROL2 may have arisen from ancestral TROL1 via gene duplication before the emergence of seed plants and acquired the CLS domain via evolution of the sequence encoding its N-terminal portion.We further reveal that TROL2(or CLS)forms an assembly cofactor complex with the intrinsic thylakoid membrane protein LOW PSⅡ ACCUMULATION2 and interacts with small PSⅡ subunits to facilitate PSⅡ complex assembly.Collectively,our study not only shows that TROL2(CLS)is essential for photoautotrophy in angiosperms but also reveals its mechanistic role in PSⅡ complex assembly,shedding light on the molecular and evolutionary mechanisms of photosynthetic complex assemblyin angiosperms. | Wei Li Jiangfan Guo Xue Han Xiaowen Da Kai Wang Hongfei Zhao Shi-Tang Huange Bosheng Li Hang He Ruirui Jiang Shichen Zhou Peng Yan Tao Chen Yi He Jiming Xu Yu Liu Yunrong Wu Huixia Shou Zhongchang Wu Chuanzao Mao Xiaorong Mo | 2023 | Molecular Plant2023，16，2： | 0 |
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