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| 1 | Chinese Stroke Association guidelines for clinical management of cerebrovascular disorders:executive summary and 2019 update of the management of high-risk population显示文摘Aim Cerebrovascular disease is the leading cause of death and disability in China,causing a huge burden among patients and their families.Hence,stroke prevention is critical,especially in the high-risk population.Here,we present the evidence-based guideline suitable for the Chinese population.Methods Literature search of PubMed and Cochrane library(from January 1964 to June 2019)was done.After thorough discussion among the writing group members,recommendations were listed and summarised.This guideline was reviewed and discussed by the fellow writing committees of the Chinese Stroke Association’s Stroke.Results This evidence-based guideline was written in three parts:controlling the risk factors of stroke,utilisation of antiplatelet agents and assessing the risks of first-ever stroke.All recommendations were listed along with the recommending classes and levels of evidence.Conclusions This guideline provides recommendations for primary prevention of cerebrovascular disease among high-risk population in China.Controlling related risk factors,appropriately using antiplatelet agents,assessing the risk of developing first-ever stroke should help reduce the rate of cerebrovascular disease in China. | Yilong Wang Shangrong Han Haiqiang Qin Huaguang Zheng Bin Jiang Yong Cao Yuan Gao Ling Guan Qian Jia Yong Jiang Yuming Jiao Shuya Li Yapeng Li Zixiao Li Wei Liu Xiaojuan Ru Dongling Sun Haixin Sun Penglian Wang Tingting Wang Lixia Zong Lei Guo Xuewei Xie Yuming Xu Yuyuan Xu Xiaomeng Yang Yingying Yang Mengyuan Zhou Wenzhi Wang Chinese Stroke Association Stroke Council Guideline Writing Committee | 2020 | Stroke & Vascular Neurology2020，5，3： | 11 |
| 2 | Small Interfering RNA-mediated Caveolin-1 Knockout on Plasminogen Activator Inhibitor-1 Expression in Insulin-stimulated Human Vascular Endothelial Cells显示文摘把人的脉管的 endothelial 房间(ECV304 ) 用作目标,我们学习了 caveolin (CAV ) 的效果在 plasminogen 的刺激胰岛素的表示期间的 -1 禁止者(白族)-1。代表 RNAi CAV-1 基因的适当搁浅单人赛的 oligonucleotides 被 Ambion 软件分析。在退火产生双 stranded oligonucleotides (dsoligo ) 以后,它被克隆进由 T4 DNA 连接酶包含 RNA 聚合酶 III 表示元素的 pENTR/U6 入口向量。从 pENTR/U6 入口转移的短发卡(shRNA ) 序列与 LR 再结合反应被克隆进 pLenti6/BLOCK-iT-DEST 向量。由定序的 Afteridentification,我们成功地用网关技术构造了 CAV-1 RNAi lentiviral 表达式系统。Silencing 效率是由即时 reversetranscription 聚合酶链反应,免疫荧光染色并且西方的弄污的 assayed。ECV304cells 在包含胰岛素的不同集中的媒介是有教养的(1x10 ^( 有 CAV-1 基因 silenced 的 -9)to1x10^(-7) M ) 。表示水平和潜水艇 PAI-1 和 CAV-1 的细胞的本地化用反向的抄写聚合酶链反应,免疫荧光染色和蛋白质印迹试金被比较。结果证明有势力抑制 ofCAV-1 表示能到达 85% ,并且它对 CAV-1-derived shRNA,不是导出 theS100A13 的 shRNA 特定。在蛋白质确实在房间膜下面积累了的在与生理的胰岛素,而是 PAI-1 孵化的 RNAi^+andRNAi^- ECV304 房间之间的 PAI-1 表示没有戏剧的差别。当胰岛素的集中增加了, PAI-1 的表示是起来调整的,而 CAV-1 的表示稀释了。而且, PAI-1 清楚地在 CAV-1knockdown 以后扩充了。这些结果显示 hyperinsulinism 能由 inhibitingCAV-1 支持 PAI-1 表示,并且稳定或在 endothelial 房间的起来调整的 CAV-1 表示可能在糖尿病减少大容器和毛状的容器的复杂并发症。 | Huiling YANG Shuya HE Zhihua QUAN Weixia PENG Bin YAN Jianghua LIU Fang WEN Renxian CAO Yangyan XU Gebo WEN Weixin HU | 2007 | Acta Biochimica et Biophysica Sinica2007，39，3： | 7 |
| 3 | Intake of Vitamin A,Thiamine,Riboflavin,Vitamin C,and Niacin Among Children Aged 6−11 Years Old—China,2016−2017显示文摘Summary What is already known on this topic?Insufficient intake of vitamins is one of the major nutritional problems in children aged 6-11 years old in China,and the problem is particularly severe for rural populations.What is added by this report?Among children aged 6-11 years old in 2016-2017,the average intakes of vitamin A,thiamine. | Wei Piao Lahong Ju Hongyun Fang Qiya Guo Shuya Cai Xiaoli Xu Shujuan Li Xue Cheng Liyun Zhao Dongmei Yu | 2021 | China CDC weekly2021，3，11： | 3 |
| 4 | Cooking Oil and Salt Intakes Among Children Aged 6−17 Years——China,2016−2017显示文摘Summary What is already known on this topic?High-level intakes of both cooking oil and salt are issues of concern in China as they can lead to an increased risk of chronic diseases later in life.Reducing intakes of cooking oil and salt should be prioritized in children.What is added by this report?Among children aged 6-17 years in China in 2016-2017,the median intake of cooking oil and salt were 27.7 and 6.1 g/d,respectively.The percentages of children with intake of cooking oil and salt that exceeded the recommended guidelines were 50.4%and 67.8%,respectively. | Lahong Ju Dongmei Yu Wei Piao Hongyun Fang Qiya Guo Xiaoli Xu Shujuan Li Xue Cheng Shuya Cai Liyun Zhao | 2021 | China CDC weekly2021，3，31： | 3 |
| 5 | Understanding the phase separation characteristics of nucleocapsid protein provides a new therapeutic opportunity against SARS-CoV-2显示文摘Dear Editor To date,tens of millions of people have been infected with severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),causing the outbreak of the respiratory disease named the coronavirus disease 2019(COVID-19).As a newly emerged member of the coronavirus family,SARS-CoV-2 is an enveloped positive-strand RNA virus,which has probably the largest genome(approximately 30 kb)among all RNA viruses.The nucleocapsid(N)protein of SARS-CoV-2 is mainly responsible for recognizing and wrapping viral RNA into helically symmetric structures(Malik,2020). | Dan Zhao Weifan Xu Xiaofan Zhang Xiaoting Wang Yiyue Ge Enming Yuan Yuanpeng Xiong Shenyang Wu Shuya Li Nian Wu Tingzhong Tian Xiaolong Feng Hantao Shu Peng Lang Jingxin Li Fengcai Zhu Xiaokun Shen Haitao Li Pilong Li Jianyang Zeng | 2021 | Protein & Cell2021，12，9： | 1 |
| 6 | Consumption of Milk and Dairy Products Among Junior High and Senior High School Students — China, 2016–2017显示文摘Summary What is already known about this topic?Chinese dietary guidelines recommend an intake of milk and dairy products to be closely related to human health.Although the production capacity of dairy in China is strong,the per capita consumption of dairy products is not high.What is added by this report?This report showed that the consumption rate of milk and dairy products of junior high and senior high school students in China was 82.5%from 2016 to 2017.Only 44.1%of them consumed milk and dairy products every day.Only 20.4%of these students reached intake levels recommended by the Dietary guidelines for Chinese residents(2016).What are the implications for public health practice?Milk and dairy products are a key food group in a healthy dietary pattern.To cultivate a healthy eating habit of including dairy for children and adolescents,the government,suppliers,schools,and parents need to cooperate together. | Xiaoli Xu Xue Cheng Liyun Zhao Hongyun Fang Qiya Guo Lahong Ju Shujuan Li Shuya Cai Wei Piao Dongmei Yu | 2022 | China CDC weekly2022，4，3： | 0 |
| 7 | 城·学显示文摘城市校园作为一种建筑意向和形式,已经与城市肌理交织变化为一体。在21世纪的今天,校园的概念应该更为繁复和综合。它应该更加强调人的融合、功能的塑造以及组成我们学习与生活交互空间的参与。我们的灵感来源来自美国墨西哥城。在我们学习和停留墨西哥城的期间,我们不仅注意到她勃勃生机与脆弱的并存,同时也发现其空间的不确定性和可塑造性,二者都是墨西哥城非常吸引人且不可分割的一部分。墨西哥城里的校园,在我们看来,是多功能公共空间的一个最好例子。由于在墨西哥这样的国家城市基础设施建设的资金有限,我们希望能建立一个可以和城市融为一体的校园。它能够与当地的街道、社区融合,甚至成为这个城市的标志和中心。 | xu shuya huang yiwei lee hsin-han maria arquero de alarcon(指导) mclain clutter(指导) | 2016 | 城市环境设计2016，0，1： | 0 |
| 8 | Multifunctional self-delivery micelles targeting the invasion-metastasis cascade for enhanced chemotherapy against melanoma and the lung metastasis显示文摘Metastasis is closely related to the high mortality of cancer patients,which is regulated by multiple signaling pathways.Hence,multiphase blocking of this biological process is beneficial for cancer treatments.Herein,we establish a multifunctional self-delivering system by synthesizing D-α-tocopheryl succinates(TOS)-conjugated chondroitin sulfate(CS)(CT NPs),which both serve as nanocarrier and antimetastatic agent that affects different phases of the metastatic cascade.TOS as the hydrophobic segment of CT NPs can inhibit the secretion of matrix metalloproteinase-9,while the hydrophilic segment CS targets B16F10 cells through CD44 receptors and reduces the interaction between tumor cells and platelets.The results show that CT NPs are able to inhibit metastasis successfully both in vitro and in vivo by interfering the multiphase of the metastatic cascade.Following encapsulating chemotherapeutic drug doxorubicin(DOX),the obtained micelles CT/DOX efficiently suppress both primary-tumor growth and metastases in B16F10 bearing mice.As a result,the rationally designed multifunctional NPs composing of biocompatible materials provide excellent therapeutic effects on solid tumors and metastases。 | Shanshan Xu Chunyu Liu Shuya Zang Jiaxin Li Yashi Wang Kebai Ren Man Li Zhirong Zhang Qin He | 2021 | Asian Journal of Pharmaceutical Sciences2021，16，6： | 0 |
| 9 | β-decay Study of Tz=-3/2Proton-rich Nucleus 29S显示文摘The exotic decay of nuclei far from the stability has recently become a hot topic of nuclear structure research.The nuclide 29S is not well investigated in the A=4n+1,Tz=-3/2series of strong+β-delayed proton precursors.The decay schemes of these nuclei are characterized | ZHONG Fupeng XU Xinxing LIN Chengjian WANG Jiansong LI Zhihuan YANG Lei MA Nanru WANG Dongxi WEN Peiwei SUN Lijie WU Hongyi LUO Diwen WU Chenguang JIANG Ying LIU Yang ZANG Hongliang LIANG Pengfei LI Pengjie LI Xiaojing ZHAO Qingqing SHI Guozhu MA Junbing MA Peng YU Gongming Dipikap Patel BAI Zhen YANG Feng JIA Huiming ZHANG Huanqiao WANG Jianguo YANG Yanyun MA Weihu HU Qiang JIN Shuya ZHOU Xiaohong LI Ren HOU Dongsheng LIU Minliang HU Zhengguo MA Xinwen YANG Weiqing GAO Zhihao DUAN Fangfang YU Yuechao WANG Yufeng WANG Peng ZHOU Qingwu CUI Danteng WANG Xiang HU Liyuan PAN Min ZHANG Gaolong WANG Xiaoyu | 2017 | Annual Report of China Institute of Atomic Energy2017，，1： | 0 |
| 10 | Epitaxial fabrication of AgTe monolayer on Ag(111)and the sequential growth of Te film显示文摘Transition-metal chalcogenides(TMCs)materials have attracted increasing interest both for fundamental research and industrial applications.Among all these materials,two-dimensional(2D)compounds with honeycomb-like structure possess exotic electronic structures.Here,we report a systematic study of TMC monolayer AgTe fabricated by direct depositing Te on the surface of Ag(111)and annealing.Few intrinsic defects are observed and studied by scanning tunneling microscopy,indicating that there are two kinds of AgTe domains and they can form gliding twin-boundary.Then,the monolayer AgTe can serve as the template for the following growth of Te film.Meanwhile,some Te atoms are observed in the form of chains on the top of the bottom Te film.Our findings in this work might provide insightful guide for the epitaxial growth of 2D materials for study of novel physical properties and for future quantum devices. | Haoyu Dong Le Lei Shuya Xing Jianfeng Guo Feiyue Cao Shangzhi Gu Yanyan Geng Shuo Mi Hanxiang Wu Yan Jun Li Yasuhiro Sugawara Fei Pang Wei Ji Rui Xu Zhihai Cheng | 2021 | Frontiers of physics2021，16，6： | 0 |
| 11 | Beverage Consumption of Children and Adolescents Aged 6−17 Years—China,2016−2017显示文摘Summary What is already known on this topic?Beverage consumption has become a problematic dietary behavior in children and adolescents.Excessive drinking of beverages,especially sugary beverages,can increase the risk of chronic diseases such as obesity,dental cavities,and diabetes.What is added by this report?This report revealed the beverage consumption rate was higher in males,in urban areas. | Xiaoli Xu Wei Piao Hongyun Fang Qiya Guo Lahong Ju Shuya Cai Shujuan Li Xue Cheng Liyun Zhao Dongmei Yu | 2021 | China CDC weekly2021，3，13： | 0 |
| 12 | Estimation of the Reflection of Internal Tides on a Slope显示文摘Reflection occurs when internal tides impact on a steep continental slope. Separating reflected internal tide signals from incident ones is crucial to develop the parameterization of internal tide-driven turbulent mixing on the continental slopes. In this study, the performances of three different methods for estimating internal tide reflections are examined by using two different cases. The Hilbert transform-based method is found to be more suitable than two other methods for both cases considered in this study. The two other methods are effective for westward-propagating mode-1 internal tides impacting a slope, but inappropriate in the case where internal tides radiate from a Gaussian ridge impact the slope because of their inaccurate estimation of incident internal tides in the latter case. Such inaccurate estimation further influences the extraction of reflected signals and calculation of the reflected and cross term of energy fluxes. In addition, it should be noted that, due to the use of filtering, the method based on Hilbert transform may result in slight bias when assessing the incident and reflected signals near topographic features. | WANG Shuya CAO Anzhou CHEN Xu LI Qiang SONG Jinbao MENG Jing | 2020 | Journal of Ocean University of China2020，19，3： | 0 |
| 13 | Canopy structure:An intermediate factor regulating grassland diversity-function relationships under human disturbances显示文摘Grasslands are one of the largest coupled human-nature terrestrial ecosystems on Earth,and severe anthropogenic-induced grassland ecosystem function declines have been reported recently.Understanding factors influencing grassland ecosystem functions is critical for making sustainable management policies.Canopy structure is an important factor influencing plant growth through mediating within-canopy microclimate(e.g.,light,water,and wind),and it is found coordinating tightly with plant species diversity to influence forest ecosystem functions.However,the role of canopy structure in regulating grassland ecosystem functions along with plant species diversity has been rarely investigated.Here,we investigated this problem by collecting field data from 170 field plots distributed along an over 2000 km transect across the northern agro-pastoral ecotone of China.Aboveground net primary productivity(ANPP)and resilience,two indicators of grassland ecosystem functions,were measured from field data and satellite remote sensing data.Terrestrial laser scanning data were collected to measure canopy structure(represented by mean height and canopy cover).Our results showed that plant species diversity was positively correlated to canopy structural traits,and negatively correlated to human activity intensity.Canopy structure was a significant indicator for ANPP and resilience,but their correlations were inconsistent under different human activity intensity levels.Compared to plant species diversity,canopy structural traits were better indicators for grassland ecosystem functions,especially for ANPP.Through structure equation modeling analyses,we found that plant species diversity did not have a direct influence on ANPP under human disturbances.Instead,it had a strong indirect effect on ANPP by altering canopy structural traits.As to resilience,plant species diversity had both a direct positive contribution and an indirect contribution through mediating canopy cover.This study highlights that canopy structure is an important intermediate factor regulating grassland diversity-function relationships under human disturbances,which should be included in future grassland monitoring and management. | Xiaoxia Zhao Yuhao Feng Kexin Xu Mengqi Cao Shuya Hu Qiuli Yang Xiaoqiang Liu Qin Ma Tianyu Hu Maggi Kelly Qinghua Guo Yanjun Su | 2023 | Fundamental Research2023，3，2： | 0 |
| 14 | 通过^(1)H(^(15)O,p)^(15)O弹性散射来研究^(16)F的能级性质显示文摘The understanding of open quantum systems in unbound nuclei is a challenge to the nuclear structure research[1].The continuum coupling effect may lead to a reordering of the shells in such systems[2].A way to study this effect is to compare the level schemes of two mirror nuclei involving an unbound and a bound nucleus such as 16F and 16N[3].Here we report an experiment of studying the level properties of 16F using the resonant elastic scattering with an 15O radioactive beam delivered by the Radioactive Ion Beam Line at Lanzhou(RIBLL)[4]. | Ru Longhui Hu Jun Liu Enqiang Bai Zhen Duan Fangfang Fang Xiao Hou Suqing Hu Qiang Ji Liancheng Jin Shuya Li Kuoang Li Yiyang Li Ruojie Ma Peng Ma Junbing Sun Xinxin Shi Guozhu Tang Xiaodong Wang Xinyu Wang Jiansong Wang Yufeng Wu Jiatong Xu Xiaodong Xu Shiwei Xin Wenyu Yang Kaiping Yang Yanyun NMichel | 2018 | IMP & HIRFL Annual Report2018，，1： | 0 |
| 15 | Density Perturbation and Energy Flux of Internal Waves from Velocity Data显示文摘Internal waves play a crucial role in ocean mixing, and density perturbation and energy flux are essential quantities to investigate the generation and propagation of internal waves. This paper presents a methodology for calculating density perturbation and energy flux of internal waves only using a velocity field that is based on linearized equations for internal waves. The method was tested by numerical simulations of internal waves generated by tidal flowing over a Gaussian topography in a stratified fluid. The density perturbations and energy fluxes determined using our method that only used velocity data agreed with density perturbations and energy fluxes determined by the equation of state based on temperature data. The mean relative error(MRE) and root mean square error(RMSE) between the two methods were lower than 5% and 10% respectively. In addition, an experiment was performed to exam our method using the velocity field measured by Particle Image Velocimetry(PIV), and the setup of the experiment is consistent with the numerical model. The results of the experiments calculated by the methods using PIV data were also generally equal to those of the numerical model. | WANG Shuya WANG Jinhu CHEN Xu MENG Jing WANG Huan | 2018 | Journal of Ocean University of China2018，17，4： | 0 |
| 16 | Energy and Macronutrient Intake Among Children Aged 6−11 Years Old—China,2016−2017显示文摘Summary What is already known on this topic?Low level energy and macronutrient intakes and dietary imbalances are still important issues and should be prioritized in children aged 6-11 years old in China.What is added by this report?Among children aged 6-11 years in China in 2016-2017,the average protein intake was 55.2 g/d in urban areas and was higher than the estimated 45.4 g/d in rural areas. | Lahong Ju Wei Piao Hongyun Fang Qiya Guo Shuya Cai Xiaoli Xu Shujuan Li Xue Cheng Dongmei Yu Liyun Zhao | 2021 | China CDC weekly2021，3，9： | 0 |
| 17 | Experimental Study of the Elastic Scattering and Breakup Reactions of Proton Drip-line Nucleus^(8)B on^(208)Pb at energies around Four Times of Coulomb Barrier显示文摘First measurement of the angular distribution of breakup reaction for^(8)B on a^(208)Pb target at an energy around four times of Coulomb barrier was carried out at the National Laboratory of Heavy Ion Research of Institute of Modern Physics. | Wang Kang Yang Yanyun Duan Fangfang Pang Danyang Wang Jiansong Gao Zhihao Ma Peng Xu Shiwei Liu Xingquan Ma Junbing Bai Zhen Hu Qiang Jin Shuya Sun Zhiyu | 2019 | IMP & HIRFL Annual Report2019，，1： | 0 |
| 18 | Construction of diverse C–S/C–Se bonds via nickel catalyzed reductive coupling employing thiosulfonates and a selenosulfonate under mild conditions显示文摘A nickel-catalyzed reductive cross coupling between organic iodides and thiosulfonates and a selenosulfo-nate under mild conditions is disclosed.This practical method provides a facile access to a series of unsym-metrical thioethers with low catalyst loading,good functional group tolerance,and excellent chemo-selectivity. | Yong Liu Shuya Xing Jing Zhang Wen Liu Yuenian Xu Yan Zhang Kefang Yang Lei Yang Kezhi Jiang Xinxin Shao | 2022 | Organic Chemistry Frontiers2022，9，5： | 0 |
| 19 | 2-16 Experimental Study of 13N(α,p)16O at the Stellar Energies显示文摘The presolar SiC grains[1]carry the original stellar nucleosynthesis signature.Their isotopic anomalies compared to the sun are the strong constrains in the supernovae(SN)model calculations.The 15N-excess in some SiC-AB grains(12C/13C<10 and 14N/15N<272)is one of the challenges of core-collapse supernovae(CCSNe)models[2].Recently,Pignatari pointed out that the entrainment of H-rich material into the He shell before the SN explosion allows the coproduction of 13C,15N and 26Al,which provides a new production scenario for SiC-AB grains[2].In the He shell nucleosynthesis,the 13C is produced through 12C(p,γ)13N(β+γ)13C reaction.The 14N is synthesized through 13N(n,γ)and 13C(p,γ)reactions. | Lin Weiping Ma Shaobo Hu Jun Bai Zhen Chen Han Chen Zhijun Duan Fangfang Gao Bingshui Gao Zhihao Hou Suqing Ji Liancheng Jia Baolu Jiao Lei Jin ShuYa Liu Xingquan Li Kuoang Lu Tan Ma Junbing Ma Peng Tang Xiaodong Wang Xinyu Xu Shiwei Yang Yanyun Yu Gongming Yu Xiangqing Zhai Yaojie Zhang Ningtao Zhang Xing | 2016 | IMP & HIRFL Annual Report2016，，1： | 0 |
| 20 | On the Generation and Evolution of Internal Solitary Waves in the Andaman Sea显示文摘Internal solitary waves(ISWs)are ubiquitous in the Andaman Sea,as revealed by synthetic aperture radar images;however,their generation mechanisms and corresponding influencing factors remain unknown.Based on a nonhydrostatic two-dimensional model,the generation of ISW packets along the transect of a channel lying between Batti Malv Island and Car Nicobar Island is investigated.Moreover,the influences of topographic characteristics,seasonal stratifications,and tidal forcings are analyzed through a series of sensitivity runs.The simulation results indicate that bidirectional rank-ordered ISW packets are generated by the nonlinear steepening of internal tides.An east-west ISW asymmetry is observed,which is attributed to distinct topographic characteristics.The surrounding sills can also generate internal wave beams,which modulate the intensity of ISWs.However,the topographic structure of the west flank of the ridge mainly contributes to the suppression of westward ISWs,which decreases the modulating effect of internal wave beams.During the spring tide,the generation of ISWs is enhanced.During the neap tide,ISWs are weak,and the east-west ISW asymmetry is less obvious.Moreover,seasonal stratification only has a minor effect on the generation and evolution of ISWs. | YU Yujun XU Tao WANG Jinhu WANG Shuya LI Qun MENG Jing CHEN Xu LU Kexiao WANG Guixia | 2023 | Journal of Ocean University of China2023，22，2： | 0 |
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