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| 1 | Global transcriptome analysis for identification of interactions between coding and noncoding RNAs during human erythroid differentiation显示文摘在 erythroid 开发期间编码基因, miRNAs,和 lncRNAs 上的研究在最近的年里被执行了。然而,集中于三种 RNA 类型的集成的分析还得被做。在现在的学习,我们比较了编码基因, miRNA,和 lncRNA 表示侧面的动力学。为了在在 transcriptome 控制这些变化的红血球生成和潜在的机制探索动态变化,铺平,我们利用了定序技术从绳索血获得 transcriptome 数据的高产量造血的干细胞和下列四个 erythroid 区别阶段,以及从成熟的红血房间。结果显示 lncRNAs 为 erythroid 区别正在答应房间标记候选人。聚类分析分类差别表示基因进在 stemness 维护期间对应于动态变化的四种子类型,中间区别,并且成熟。综合分析揭示了 RNA 潜在地参予了控制血细胞成熟的那 noncoding,并且特别与到氧种类和 DNA 损坏的 heme 新陈代谢和回答联系了。这些规章的相互作用在一个全面网络,在 RNA 之间的从而推断的关联和他们的联系功能被显示。这些数据为正常红血球生成的学习提供了一个大量的资源,它将允许 erythroid 开发的进一步的调查和理解并且获得 erythroid 混乱。 | Nan Ding Jiafei Xi Yanming Li Xiaoyan Xie Jian Shi Zhaojun Zhang Yanhua Li Fang Fang Sihan Wang Wen Yue Xuetao Pei Xiangdong Fang | 2016 | Frontiers of Medicine2016，10，3： | 6 |
| 2 | Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species显示文摘在现在的学习,我们识别了从 Amolops daiyunensis, Pelophylax hubeiensis, Hylarana maosuoensis 和 Nanorana pleskei 与抗氧化剂或抗菌剂活动被分类进 21 个肽家庭的 50 肽,它在 Ranidae 和 Dicroglossidae 家庭属于四个不同的类。这四青蛙种第一次被作出对有利的裁决表示抗氧化剂肽(AOP ) 和抗菌剂肽(安培) 。这些肽包括七最新发现的家庭 daiyunin-1, daiyunin-2, daiyunin-3, maosonensis-1MS1, pleskein-1, pleskein-2,和 pleskein-3。抗氧化剂和抗菌剂活动试金证明一些这些肽举办好生物活动。例如,在两个都展出的 50 M, nigroain-B-MS1,和 nigroain-C-MS1 的集中,相对强壮的 2,2-diphenyl-1-picrylhydrazyl (DPPH ) 和 2,2-azinobis-(3-ethylbenzothiazoline-6-sulfonicacid )(ABTS ) 释放激进的清除能力与 99.7% 和 68.3% 的根除率(nigroain-B-MS1 ) ,并且 99.8% 和 58.3%(nigroain-C-MS1 ) 分别地。这些肽是新奇抗氧化剂或安培准备的发展的潜在的候选人。 | Xiao Wang Shuguang Ren Chao Guo Weiqi Zhang Xiaoli zhang Baowen Zhang Sihan Li Jian Ren Yuhong Hu Hui Wang | 2017 | Acta Biochimica et Biophysica Sinica2017，49，6： | 3 |
| 3 | BMAL1 functions as a cAMP-responsive coactivator of HDAC5 to regulate hepatic gluconeogenesis显示文摘 | Jian Li Sihan Lv Xinchen Qiu Jiamin Yu Junkun Jiang Yalan Jin Wenxuan Guo| Ruowei Zhao Zhen-Ning Zhang Chao Zhang Bing Luan | 2018 | Protein & Cell2018，9，11： | 3 |
| 4 | CAPE promotes the expansion of human umbilical cord blood-derived hematopoietic stem and progenitor cells in vitro显示文摘Due to the low number of collectable stem cells from single umbilical cord blood(UCB)unit,their initial uses were limited to pediatric therapies.Clinical applications of UCB hematopoietic stem and progenitor cells(HSPCs)would become feasible if there were a culture method that can effectively expand HSPCs while maintaining their self-renewal capacity.In recent years,numerous attempts have been made to expand human UCB HSPCs in vitro.In this study,we report that caffeic acid phenethyl ester(CAPE),a small molecule from honeybee extract,can promote in vitro expansion of HSPCs.Treatment with CAPE increased the percentage of HSPCs in cultured mononuclear cells.Importantly,culture of CD34+HSPCs with CAPE resulted in a significant increase in total colony-forming units and high proliferative potential colony-forming units.Burst-forming unit-erythroid was the mostly affected colony type,which increased more than 3.7-fold in 1μg mL 1CAPE treatment group when compared to the controls.CAPE appears to induce HSPC expansion by upregulating the expression of SCF and HIF1-α.Our data suggest that CAPE may become a potent medium supplement for in vitro HSPC expansion. | LIU YiMing ZHANG BoWen ZHANG Jing WANG SiHan YAO HaiLei HE LiJuan CHEN Lin YUE Wen LI YanHua PEI XueTao | 2014 | Science China(Life Sciences)2014，57，2： | 2 |
| 5 | Thermal Behavior Analysis of Stacked-type Supercapacitors with Different Cell Structures显示文摘As a new energy storage element,supercapacitors have characteristics such as high power density,fast charge and discharge rates,green environmental protection,and long cycle life.Temperature is an important parameter of supercapacitors which significantly influences the stability of the supercapacitors.In this study,the finite element method is used to realize a coupling between a one-dimensional electrochemical model and a three-dimensional thermal model.Then,based on this model,the concept of limited cycle numbers is defined,and different unit quantities,unit size,and the effect of temperature under different temperature environments such as low temperature,room temperature,and high temperature on stacked-type supercapacitors is studied.Finally,stacked-type supercapacitors are compared with rolled-type supercapacitors considering the same cell size,density,and volume approximations.The simulation results show that the higher the number of packaging units,the lower is the limit cycle number.This phenomenon is more pronounced under high current than under low current conditions.Increasing the package size of the porous electrode or separator decreases the limiting cycles.Under the same unit volume scenario,improving the separator size proportion can accurately control the temperature rise at small current values.Under the same material,volume,and density approximations,the temperature rises slowly for stacked-type supercapacitors as compared to rolled-type supercapacitors.This phenomenon is more pronounced with an increase in current. | Yansong Li Sihan Wang Meina Zheng Jun Liu | 2018 | CSEE Journal of Power and Energy Systems2018，4，1： | 2 |
| 6 | Preparation of antifouling ultrafiltration membranes from copolymers of polysulfone and zwitterionic poly(arylene ether sulfone)s显示文摘The past few decades have witnessed rapid gains in our demands of antifouling membranes such as water purification membranes and hemodialysis membranes.A variety of methodologies have been proposed for improving the antifouling performance and the hemocompatibility of the membranes.In this study,a series of copolymers(PSF-PESSB)containing polysulfone(PSF)and poly(arylene ether sulfone)bearing pendant zwitterionic sulfobetaine groups(PESSB)were prepared via one-pot polycondensation.Subsequently,the ultrafiltration(UF)membranes were prepared from different zwitterion-containing copolymers.The prepared membranes showed high thermal stability and mechanical properties.Besides,it also displayed attractive antifouling performance and blood compatibility.Compared with the original PSF membrane,the amount of protein absorption on the modified membrane was reduced;the flux recovery ratio and the resistance to blood cells were significantly improved.The results of this work suggest that PSF-PESSB membranes are expected to be applied in blood purification.The introduction of zwitterion-containing polymers to membranes paves ways for developing advanced hemodialysis technologies for crucial process. | Sihan Huang Yaohan Chen Xue Wang Jing Guo Yonggang Li Lei Dai Shenghai Li Suobo Zhang | 2022 | Chinese Journal of Chemical Engineering2022，35，9： | 1 |
| 7 | Immnnomodulatary effects of polysaccharopeptide ( PSP ) in human PBMC through regulation ff TRAF6/TLR immunosignal-transduction palhways 显示文摘 | Wenwen Li Manran Liu Sihan Lai | 2010 | Immunopharmacology and Immunotoxicology2010，32，4： | 1 |
| 8 | Plasma miR-126 Is a Potential Biomarker for Early Prediction of Type 2 Diabetes Mellitus in Susceptible Individuals显示文摘 | Tao Zhang Chunfang Lv Liling Li Sihan Chen Shenglin Liu Changyi Wang Bing Su Thean Hock Tang | 2013 | BioMed Research International2013，，： | 1 |
| 9 | Multimaterial additive manufacturing manipulator for fabricating magnetoelectric pressure sensors显示文摘The simultaneous placement of different types of materials including polymers,ceramics,and metals,in their desired positions could be adopted to manufacture end-use devices/apparatuses with diverse functionalities and significantly reduce the fabrication cost and time.However,existing additive manufacturing(AM)approaches can only treat one material species at a time due to their intrinsic working mechanisms.Here we develop an AM manipulator for manufacturing a wide variety of material species,including polymers,ceramics,and metals,through a multifilament transport strategy assisted by laser power.The six-jaw manipulator contains three pairs of filament delivering/cutting systems for transporting diverse materials and a beam of tunable laser as the thermal source.The whole apparatus is integrated into a robotic manipulator to create a multifreedom manufacturing platform.With this innovation,products with multiple material species and desired complex geometries can be fabricated on demand.Furthermore,we synthesize a multimaterial(polymer/ceramic/metal)printed magnetoelectric pressure sensor that can convert applied mechanical forces to electricity and maintain efficiency even after undergoing 10000 cycles of pressure/recovery.With this multimaterial filament transport and laser manufacturing strategy,our AM manipulator exhibits promising application in the advanced manufacturing of embedded electronics,sensors,soft robotics,and customizable medical devices. | LIU ZhuFeng LI ZhaoQing WANG Qi WANG Yan YANG Lei NIE Xiang GENG Peng WU ZhenHua TANG SiHan YANG Lei WU HongZhi SHI YunSong CHEN Peng SU Bin ZHANG LiChao YAN ChunZe SHI YuSheng | 2022 | Science China(Technological Sciences)2022，65，11： | 1 |
| 10 | Triptolide Cooperates With Cisplatin to Induce Apoptosis in Gemcitabine-Resistant Pancreatic Cancer显示文摘 | Zhu Wenbo MD Li Jingjie MMed Wu Sihan BSc | 2012 | Pancreas2012，419，7： | 1 |
| 11 | Severe Vitamin D-deficiency and the Health of North China Children显示文摘 | Mark A. Strand Judith Perry Jinping Zhao Philip R. Fischer Jianping Yang Sihan Li | 2009 | Maternal and Child Health Journal2009，，1： | 1 |
| 12 | cAMP-PGC1α途径诱导的抗Warburg效应驱动胶质母细胞瘤细胞分化为星形胶质细胞显示文摘文章简介多形性胶质母细胞瘤(GBM)是人类最具侵袭性的肿瘤之一。虽然分化治疗已被提出作为治疗GBM的潜在方法,但诱导分化的机制仍然很不清楚。在此,课题组利用c AMP激活剂建立了GBM诱导分化模型,该模型特异性地指导GBM分化为星形胶质细胞。 | Fan Xing Yizhao Luan Jing Cai Sihan Wu Jialuo Mai Jiayu Gu Haipeng Zhang Kai Li Yuan Lin Xiao Xiao Jiankai Liang Yuan Li Wenli Chen Yaqian Tan Longxiang Sheng Bingzheng Lu Wanjun Lu Mingshi Gao Pengxin Qiu Xingwen Su Wei Yin Jun Hu Zhongping Chen Ke Sai Jing Wang Furong Chen Yinsheng Chen Shida Zhu Dongbing Liu Shiyuan Cheng 谢志 朱文博 颜光美 | 2018 | 科学新闻2018，0，4： | 1 |
| 13 | Therapeutic effect of Qinghuayin(清化饮)against chronic atrophic gastritis through the inhibition of toll or interleukin-1 receptor domain-containing adaptor inducing interferon-β signaling pathway显示文摘OBJECTIVE:To examine the efficacy of Qinghuayin(清化饮,QHY)in rat chronic atrophic gastritis(CAG)models and explored the molecular mechanism of QHY in treating CAG.METHODS:In total,65 Wistar rats were randomly divided into the control(n=10)and CAG groups(n=55).CAG model rats were further divided into five groups:model(n=10),vitacoenzyme(n=10),low-dose QHY(n=10),medium-dose QHY(n=10),and high-dose QHY groups(n=10).We analyzed histopathological changes using hematoxylin and eosin staining and measured interleukin(IL)-6 and IL-8 levels in serum using enzyme-linked immunosorbent assay(ELISA)(Boster Bio,Pleasanton,USA).In addition,gastrin(GAS),pepsinogen I(PGI),and PGII expressions were evaluated using ELISA.The protein and m RNA expression of toll-like receptor 4(TLR4)and toll or interleukin-1 receptor domaincontaining adaptor inducing interferon-β(TRIF)was detected by Western blotting and quantitative reverse transcription-polymerase chain reaction,respectively.RESULTS:Our results revealed that histopathological changes in CAG model rates could be restored by low-,medium-,and high-dose QHY.The changes in GAS and PGI/II expression demonstrated that QHY improved CAG.Serum IL-6 and IL-levels were decreased by QHY administration.TLR4 and TRIF were upregulated at the m RNA and protein levels in the model group but downregulated by QHY administration.CONCLUSION:We concluded that QHY could effectively improve the histopathological changes of the gastric mucosa induced by CAG in rats.The therapeutic mechanism of QHY may be related to inhibition of the inflammatory factors IL-6 and IL-8 and suppression of TLR4/TRIF m RNA and protein expression. | HE Youcheng YAO Xiaoling LI Sihan ZHOU Hongjian XU Ruoying ZHENG Rong XIAO Wendi SU Ning LIN Ping HUANG Minghan | 2022 | Journal of Traditional Chinese Medicine2022，42，2： | 1 |
| 14 | All-fiber generation of arbitrary cylindrical vector beams on the first-order Poincare sphere显示文摘We propose a linear mapping relationship between the polarization of the fundamental mode and the cylindrical vector(CV)modes on the first-order Poincaresphere(FOPS)in fiber.The new method is based on the fourdimensional complex Jones matrices in terms of the linearly polarized mode bases.With our theoretical model,an all-fiber approach to generate arbitrary CV beams on the FOPS is proposed theoretically and verified experimentally.In the experiment,through the combination of a mode converter and a two-segment cascaded few-mode fiber with fixed stresses,it is possible to generate all CV modes on the FOPS by only adjusting the polarization of the fundamental mode.The Stokes parameters of the output light are measured to verify our scheme,which shows good agreement with the theoretical prediction.The method may provide a convenient way to generate CV beams and evolve the polarization states in any path on the FOPS,which is expected to have potential applications in encoding information and quantum computation. | LIPENG FENG YAN LI SIHAN WU XUN GUAN CHEN YANG WEIJUN TONG WEI LI JIFANG QIU XIAOBIN HONG YONG ZUO HONGXIANG GUO ERHU CHEN JIAN WU | 2020 | Photonics Research2020，8，8： | 1 |
| 15 | A Lightweight Model of VGG-U-Net for Remote Sensing Image Classification显示文摘Remote sensing image analysis is a basic and practical research hotspot in remote sensing science.Remote sensing images contain abundant ground object information and it can be used in urban planning,agricultural monitoring,ecological services,geological exploration and other aspects.In this paper,we propose a lightweight model combining vgg-16 and u-net network.By combining two convolutional neural networks,we classify scenes of remote sensing images.While ensuring the accuracy of the model,try to reduce the memory of themodel.According to the experimental results of this paper,we have improved the accuracy of the model to 98%.The memory size of the model is 3.4 MB.At the same time,The classification and convergence speed of the model are greatly improved.We simultaneously take the remote sensing scene image of 64×64 as input into the designed model.As the accuracy of the model is 97%,it is proved that the model designed in this paper is also suitable for remote sensing images with few target feature points and low accuracy.Therefore,the model has a good application prospect in the classification of remote sensing images with few target feature points and low pixels. | Mu Ye Li Ji Luo Tianye Li Sihan Zhang Tong Feng Ruilong Hu Tianli Gong He Guo Ying Sun Yu Thobela Louis Tyasi Li Shijun | 2022 | Computers, Materials & Continua2022，，12： | 1 |
| 16 | ON DECORRELATED FAST CIPHER显示文摘Decorrelated Fast Cipher(DFC) is a candidate for the Advanced Encryption Standard (AES). It is shown that the cryptographic properties of the confusion permutation of DFC are weak in this paper. With the same F-function of DFC, a Feistel cipher VDFC which has no resistance against differential cryptanalysis is constructed. This demonstrates the importance of the key addition into DFC sufficiently. As a result, DFC may not be qualified candidate for the AES. | Wu Wenling Li Bao Feng Denguo Qing Sihan(Engineering Research Center for Information Security Technology,Chinese Academy of Sciences, Beijing 100080) | 2000 | Journal of Electronics(China)2000，17，1： | 0 |
| 17 | J-comb: An image fusion algorithm to combine observations covering different spatial frequency ranges显示文摘Ground-based, high-resolution bolometric(sub)millimeter continuum mapping observations on spatially extended target sources are often subject to significant missing fluxes. This hampers accurate quantitative analyses. Missing flux can be recovered by fusing high-resolution images with observations that preserve extended structures. However, the commonly adopted image fusion approaches do not maintain the simplicity of the beam response function and do not try to elaborate the details of the yielded beam response functions. These make the comparison of the observations at multiple wavelengths not straightforward. We present a new algorithm, J-comb, which combines the high and low-resolution images linearly. By applying a taper function to the low-pass filtered image and combining it with a high-pass filtered image using proper weights, the beam response functions of our combined images are guaranteed to have near-Gaussian shapes. This makes it easy to convolve the observations at multiple wavelengths to share the same beam response functions. Moreover, we introduce a strategy to tackle the specific problem that the imaging at 850 μm from the present-date ground-based bolometric instrument and that taken with the Planck satellite do not overlap in the Fourier domain. We benchmarked our method against two other widely-used image combination algorithms, CASA-feather and MIRIAD-immerge, with mock observations of star-forming molecular clouds. We demonstrate that the performance of the J-comb algorithm is superior to those of the other two algorithms. We applied the J-comb algorithm to real observational data of the Orion A star-forming region. We successfully produced dust temperature and column density maps with ~10′′angular resolution, unveiling much greater details than the previous results. A py Thon code release of J-comb and implementation of the algorithm are available at http://gffzz188fe103f8f1460as060xq5ncc9b96qoo.ffgz.tsg.suse.edu.cn/Sihan Jiao/J-comb. | Sihan Jiao Yuxin Lin Xiangyu Shui Jingwen Wu Zhiyuan Ren Di Li | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，9： | 0 |
| 18 | Transformer fault diagnosis based on relational teacher-student network显示文摘The analysis of dissolved gas in oil can provide an important basis for transformer fault diagnosis.In order to improve the accuracy of transformer fault diagnosis,a method based on the relational teacher-student network(R-TSN)is proposed by analyzing the relationship between the dissolved gas in the oil and the fault type.R-TSN replaces the original hard labels with soft labels,and uses it to measure the similarity between different samples in the space,to a certain extent,it can obtain the hidden feature information in the samples,and clarify the classification boundary.Through the identification experiment,the effect of R-TSN diagnosis model is analyzed,and the influence of the compound fault of discharge and thermal on the diagnosis model is studied.This paper compares R-TSN with support vector machines(SVMs),decision trees and multilayer perceptron models in transformer fault diagnosis.Experimental results show that R-TSN has better performance than the above methods.After adding compound faults in the sample set,the accuracy rate can still reach 86.0%. | Yin Sihan Li Yalei Liu Xiaoping Cui Xu Wang Huapeng | 2023 | The Journal of China Universities of Posts and Telecommunications2023，30，3： | 0 |
| 19 | Artificial Plant Seeds and Their Application显示文摘The artificial plant seed is a new technology developed on the basis of the in vitro plant culture technology.As a high-tech achievement with great development potential and economic value in the 21^(st) century,artificial plant seeds have great potential advantages.This paper briefly introduced artificial plant seeds,their composition and advantages,the preparation of artificial plant seeds and the application of artificial plant seeds. | Yilong HOU Zhiruo QI Sihan YU Chuiyu KONG Tongning BAI Qing LI | 2022 | Agricultural Biotechnology2022，11，2： | 0 |
| 20 | A novel biodegradable high nitrogen iron alloy with simultaneous enhancement of corrosion rate and local corrosion resistance显示文摘To improve the corrosion rate and suppress the local corrosion,a novel biodegradable high nitrogen(N)FeMnN alloy was developed,and the effects of N content on the corrosion behaviors were systematically investigated.It was found that,as the N content increased,the corrosion rate was significantly enhanced in both Hank’s solution and simulated gastric fluid.Meanwhile,as the N content increased,the size and depth of pits decreased obviously,and the number of pits increased,which presented a more uniform corrosion morphology.X-ray photoelectron spectroscopy(XPS)results indicated that N existed in the form of NH_(4)^(+) in the corrosion products and[FeN]clusters in the matrix.The[FeN]clusters would simultane-ously improve the corrosion rate and suppress the local corrosion,which provides a new perspective for the development of biodegradable Fe alloy. | Sihan Lu Qingchuan Wang Yi Zhang Huabing Li Hao Feng Lili Tan Ke Yang | 2023 | Journal of Materials Science & Technology2023，，21： | 0 |
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