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| 1 | Test and prediction of chloride diffusion in recycled aggregate concrete显示文摘Recycled aggregate concrete(RAC) specimens with different recycled coarse aggregate replacement ratios by mass(R) are fully immersed in a 10% chloride solution for 235 days. Both free chloride concentration(Cf) and total chloride concentration(Ct) are then measured employing a rapid chloride test(RCT) system. The Fick's second diffusion law is verified by the test data and used to predict chloride concentration distribution at different immersion periods. Additionally, pore structures of the new and old mortar in RAC are tested by mercury intrusion porosimetry(MIP). It is found that binding chloride concentration(Cb) linearly increases with Cf. In natural aggregate concrete(NAC), Cf is obviously smaller than that in the RAC in the same testing environment and this is different from the test results of Ct and Cb. Furthermore, the effects of R on the chloride concentration of RAC become severe for specimens subjected to long immersion periods, which can be explained in terms of the pore structures of the new mortar and old adhesive mortar in RAC. | XIAO Jian Zhuang YING Jing Wei TAM Vivian W.Y GILBERT Ian R | 2014 | Science China(Technological Sciences)2014，57，12： | 5 |
| 2 | 利钠肽受体2的缺乏促进小鼠二叶主动脉瓣、主动脉瓣疾病、左心室功能不全以及升主动脉扩张显示文摘主动脉瓣疾病是无有效药物治疗的细胞介导的病变过程。C型利钠肽(C-type natriuretic peptide,CNP)抑制瓣膜间质细胞(valve interstitial cells,VIC)的肌纤维形成和成骨过程,并且在出现主动脉瓣狭窄时水平下调。然而,CNP信号是否调节体内主动脉瓣的健康状态尚不清楚。该研究旨在确定小鼠CNP信号通路的缺失是否导致主动脉瓣疾病加速发展。 | 刘青 叶鹏 Blaser MC Wei K Adams RL Zhou YQ Caruso LL Mirzaei Z Lam A Tam RK Zhang H Heximer SP Henkelman M Simmons CA | 2018 | 中华高血压杂志2018，26，1： | 3 |
| 3 | Eradication of Helicobacter pylori for prevention of ulcer recurrence after simple closure of perforated peptic ulcer: A meta-analysis of randomized controlled trials显示文摘 | Chung-Shun Wong Chee-Fah Chia Hung-Chia Lee Po-Li Wei Hon-Ping Ma Shin-Han Tsai Chih-Hsiung Wu Ka-Wai Tam | 2013 | Journal of Surgical Research2013，，2： | 3 |
| 4 | CDKN2A/p16 inactivation mechanisms and their relationship to smoke exposure and molecular features in non-small-cell显示文摘 | Kit W Tam Wei Zhang Junichi | 2013 | J Thoracic Oncol2013，8，11： | 1 |
| 5 | CDKN2A/p16 Inactivation Mechanisms and Their Relationship to Smoke Exposure and Molecular Features in Non–Small-Cell Lung Cancer显示文摘 | Kit W. Tam Wei Zhang Junichi Soh Victor Stastny Min Chen Han Sun Kelsie Thu Jonathan J. Rios Chenchen Yang Crystal N. Marconett Suhaida. A. Selamat Ite A. Laird-Offringa Ayumu Taguchi Samir Hanash David Shames Xiaotu Ma Michael Q. Zhang Wan L. Lam Adi Gaz | 2013 | Journal of Thoracic Oncology2013，，11： | 1 |
| 6 | Liver transplantation is not contraindicated in infancy显示文摘 | K.L Chan S.T Fan H Saing W Wei C.M Lo I Ng N.S Tsoi J Chan W.K Tso K.Y Yuen P.K.H Tam J Wong | 2000 | Transplantation Proceedings2000，，7： | 1 |
| 7 | Systematic review of the use of a mesh to prevent parastomal hernia显示文摘 | Tam KW Wei PL Kuo LJ | 2010 | World J Surg2010，34，11： | 1 |
| 8 | Systematic review of the use of amesh to prevent parastomal hemia显示文摘 | Tam KW Wei PL Kuo U | 2010 | World J Sui^2010，，： | 1 |
| 9 | Systematic review of the use of a mesh to prevent parastomal hernia显示文摘 | Tam KW Wei PL Kuo LJ | 2010 | World J Surg2010，34，11： | 1 |
| 10 | Solid-cystic papillary tumor of the pancreas in children显示文摘 | Hong Zhou Wei Cheng K. Y. Lam Godfrey C. F. Chan P. L. Khong Paul K. H. Tam | 2001 | Pediatric Surgery International2001，，8： | 1 |
| 11 | Dynamic phenotypic heterogeneity and the evolution of multiple RNA subtypes in hepatocellular carcinoma:the PLANET study显示文摘Intra-tumor heterogeneity(ITH) is a key challenge in cancer treatment, but previous studies have focused mainly on the genomic alterations without exploring phenotypic(transcriptomic and immune)heterogeneity. Using one of the largest prospective surgical cohorts for hepatocellular carcinoma(HCC)with multi-region sampling, we sequenced whole genomes and paired transcriptomes from 67 HCC patients(331 samples). We found that while genomic ITH was rather constant across stages, phenotypic ITH had a very different trajectory and quickly diversified in stage Ⅱ patients. Most strikingly, 30% of patients were found to contain more than one transcriptomic subtype within a single tumor. Such phenotypic ITH was found to be much more informative in predicting patient survival than genomic ITH and explains the poor efficacy of single-target systemic therapies in HCC. Taken together, we not only revealed an unprecedentedly dynamic landscape of phenotypic heterogeneity in HCC, but also highlighted the importance of studying phenotypic evolution across cancer types. | Weiwei Zhai Hannah Lai Neslihan Arife Kaya Jianbin Chen Hechuan Yang Bingxin Lu Jia Qi Lim Siming Ma Sin Chi Chew Khi Pin Chua Jacob Josiah Santiago Alvarez Pauline Jieqi Chen Mei Mei Chang Lingyan Wu Brian K.P.Goh Alexander Yaw-Fui Chung Chung Yip Chan Peng Chung Cheow Ser Yee Lee Juinn Huar Kam Alfred Wei-Chieh Kow Iyer Shridhar Ganpathi Rawisak Chanwat Jidapa Thammasiri Boon Koon Yoong Diana Bee-Lan Ong Vanessa H.de Villa Rouchelle D.Dela Cruz Tracy Jiezhen Loh Wei Keat Wan Zeng Zeng Anders Jacobsen Skanderup Yin Huei Pang Krishnakumar Madhavan Tony Kiat-Hon Lim Glenn Bonney Wei Qiang Leow Valerie Chew Yock Young Dan Wai Leong Tam Han Chong Toh Roger Sik-Yin Foo Pierce Kah-Hoe Chow | 2022 | National Science Review2022，9，3： | 1 |
| 12 | Structural diversity and antioxidant activity of condensed tannins fractionated from mangosteen pericarp显示文摘 | Hai-Chao Zhou Yi-Ming Lin Shu-Dong Wei Nora Fung-yee Tam | 2011 | Food Chemistry2011，，4： | 1 |
| 13 | VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis显示文摘 | Tam BY Wei K Rudge JS | 2006 | Nat Med2006，12，7： | 1 |
| 14 | Preconditioning technique for symmetric M-matrices显示文摘 | X.-Q. Jin Y.-M. Wei H.-S. Tam | 2005 | Calcolo2005，，2： | 1 |
| 15 | One-pot synthesis of 4,8-dibromobenzobisthiadiazole显示文摘 | Tam T L Li H Wei F | 2010 | Organic Letters2010，12，15： | 1 |
| 16 | Systematic Review of the Use of a Mesh to Prevent Parastomal hernia 显示文摘 | Tam K W Wei P L Kuo L J | 2010 | World J Surg2010，34，11： | 1 |
| 17 | Systematic Review of the Use of a Mesh to Prevent Parastomal hernia显示文摘 | Tam K W Wei P L Kuo L J | 2010 | World J Surg2010，34，11： | 1 |
| 18 | VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis显示文摘 | TAM B Y WEI K RUDGE J S | 2006 | Nat Med2006，12，7： | 1 |
| 19 | Internal governance mechanisms and firm performance in China显示文摘 | Helen Wei Hu On Kit Tam Monica Guo-Sze Tan | 2010 | Asia Pacific Journal of Management2010，，4： | 1 |
| 20 | Pediatric liver transplantation in Hong Kong—a domain with scarce deceased donors显示文摘 | Kwong Leung Chan Sheung Tat Fan Chung Mau Lo William I. Wei Raymond Wai Man Ng Ho Yu Chung Kelvin Kwok Chai Ng See Ching Chan Kwok Wah Chan Wai Kuen Tso Nai Shun Tsoi Paul Kwong Hang Tam John Wong | 2009 | Journal of Pediatric Surgery2009，，12： | 1 |
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