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| 1 | Increased MicroRNA-1 and MicroRNA-133a Levels in Serum of Patients With Cardiovascular Disease Indicate Myocardial Damage显示文摘 | Yasuhide Kuwabara Koh Ono Takahiro Horie Hitoo Nishi Kazuya Nagao Minako Kinoshita Shin Watanabe Osamu Baba Yoji Kojima Satoshi Shizuta Masao Imai Toshihiro Tamura Toru Kita Takeshi Kimura | 2011 | Circulation: Cardiovascular Genetics2011,,: | 2 |
| 2 | Hepatoid adenocarcinoma of the stomach显示文摘 | Satoshi Inagawa Jiro Shimazaki Masao Hori Fuyo Yoshimi Shinya Adachi Toru Kawamoto Katashi Fukao Masayuki Itabashi | 2001 | Gastric Cancer2001,,1: | 2 |
| 3 | Mutation screening of the human Clock gene in circadian rhythm sleep disorders显示文摘 | Toshio Iwase Naofumi Kajimura Makoto Uchiyama Takashi Ebisawa Kimio Yoshimura Yuichi Kamei Kayo Shibui Keiko Kim Yoshinao Kudo Masaaki Katoh Tsuyoshi Watanabe Toru Nakajima Yuji Ozeki Mariko Sugishita Toru Hori Masaaki Ikeda Ryoichi Toyoshima Yuichi Inoue | 2002 | Psychiatry Research2002,,2: | 1 |
| 4 | Hepatoid adenocarcinoma of the stomach显示文摘 | Satoshi Inagawa Jiro Shimazaki Masao Hori Fuyo Yoshimi Shinya Adachi Toru Kawamoto Katashi Fukao Masayuki Itabashi | 2001 | Gastric Cancer2001,,1: | 1 |
| 5 | High Risk for Bradyarrhythmic Complications in Patients With Brugada Syndrome Caused by SCN5A Gene Mutations显示文摘 | Takeru Makiyama Masaharu Akao Keiko Tsuji Takahiro Doi Seiko Ohno Kotoe Takenaka Atsushi Kobori Tomonori Ninomiya Hidetada Yoshida Makoto Takano Naomasa Makita Fumiko Yanagisawa Yukei Higashi Youichi Takeyama Toru Kita Minoru Horie | 2005 | Journal of the American College of Cardiology2005,,11: | 1 |
| 6 | Hepatoid adenocarcinoma of the stomach显示文摘 | Satoshi Inagawa Jiro Shimazaki Masao Hori Fuyo Yoshimi Shinya Adachi Toru Kawamoto Katashi Fukao Masayuki Itabashi | 2001 | Gastric Cancer2001,,1: | 1 |
| 7 | FOXOland TCF7L2 genes involved in metastasis and poor prognosis in clear cell renal cell carcinoma 显示文摘 | Takahiro Kojima Toru Shimazui Ryo Horie | 2010 | Genes Chromosomes & Cancer2010,49,4: | 1 |
| 8 | Rectal angiolipoma diagnosed after surgical resection: A case report显示文摘Angiolipoma is a common benign tumor with a char- acteristic vascular component that usually occurs in subcutaneous tissue. Although lipomas are frequently encountered at colonoscopy as submucosal tumors, an- giolipomas are rarely found in the gastrointestinal tract including the large intestine. Here we report a 77-year old Japanese man who underwent transanal resection of a tumor that was diagnosed tentatively as a leiomyoma. Histologically, the tumor consisted of mature fat cells and blood vessels. Immunohistochemically, the tumor cells were negative for c-kit and HMB-45, which are consis- tently expressed in tumors such as gastrointestinal stro- mal tumor and angiomyolipoma. The tumor was there- fore diagnosed as an angiolipoma. This is thought to be the first case report of a surgically resected angiolipoma of the rectum. | Mitsuru Ishizuka Hitoshi Nagata Kazutoshi Takagi Toru Horie Akihito Abe Keiichi Kubota | 2007 | World Journal of Gastroenterology2007,13,3: | 1 |
| 9 | Ciliated hepatic foregut cyst显示文摘 | Takahiro Horii Masaharu Ohta Takashi Mori Motonari Sakai Naoki Hori Kanji Yamaguchi Hiroya Fujino Toru Oishi Yasuaki Inada Kenji Nakamura Takeshi Okanoue Kei Kashima | 2003 | Hepatology Research2003,,3: | 1 |
| 10 | PI3K-Akt inactivation induced CHOP expression in endoplasmic reticulum-stressed cells显示文摘 | Kanae Hyoda Toru Hosoi Naohiro Horie Yasunobu Okuma Koichiro Ozawa Yasuyuki Nomura | 2005 | Biochemical and Biophysical Research Communications2005,,1: | 1 |
| 11 | Inflammation-Based Prognostic Score Is a Novel Predictor of Postoperative Outcome in Patients With Colorectal Cancer显示文摘 | Mitsuru Ishizuka Hitoshi Nagata Kazutoshi Takagi Toru Horie Keiichi Kubota | 2007 | Annals of Surgery2007,,6: | 1 |
| 12 | Comparison of Corneal and Aqueous Humor Penetration of Moxifloxacin, Gatifloxacin and Levofloxacin during Keratoplasty显示文摘 | Masahiko Fukuda Masakazu Yamada Shigeru Kinoshita Tsutomu Inatomi Yuichi Ohashi Toshihiko Uno Jun Shimazaki Yoshiyuki Satake Naoyuki Maeda Yuichi Hori Kohji Nishida Akira Kubota Toru Nakazawa Yoshikazu Shimomura | 2012 | Advances in Therapy2012,,4: | 1 |
| 13 | Phase II trial on neoadjuvant intravenous and trans-uterine arterial chemotherapy for locally advanced bulky cervical adenocarcinoma显示文摘 | Hiroshi Tsubamoto Hiroaki Maeda Riichiro Kanazawa Yoshihiro Ito Naoko Ohama Masateru Hori Yuki Ikeda Toru Kato Riya Sakane Shozo Hirota | 2013 | Gynecologic Oncology2013,,: | 1 |
| 14 | Up-regulated expression of microRNA-143 in association with obesity in adipose tissue of mice fed high-fat diet显示文摘 | Rieko Takanabe Koh Ono Yukiko Abe Tomohide Takaya Takahiro Horie Hiromichi Wada Toru Kita Noriko Satoh Akira Shimatsu Koji Hasegawa | 2008 | Biochemical and Biophysical Research Communications2008,,4: | 1 |
| 15 | Oxidative stress is a triggering factor for LPS-induced Mrp2 internalization in the cryopreserved rat and human liver slices显示文摘 | Shuichi Sekine Kentaro Yano Junjiro Saeki Nozomi Hashimoto Toru Fuwa Toshiharu Horie | 2010 | Biochemical and Biophysical Research Communications2010,,2: | 1 |
| 16 | Endovascular Treatment of Spontaneous Isolated Dissecting Aneurysm of the Superior Mesenteric Artery Using Stent-Assisted Coil Embolization显示文摘 | Toshiro Ozaki Motomasa Kimura Norihiko Yoshimura Yoshiro Hori Toru Takano Takesi Kamura Satoshi Yamamoto Keisuke Sasai | 2006 | CardioVascular and Interventional Radiology2006,,3: | 1 |
| 17 | Hepatoid adenocarcinoma of the stomach显示文摘 | Satoshi Inagawa Jiro Shimazaki Masao Hori Fuyo Yoshimi Shinya Adachi Toru Kawamoto Katashi Fukao Masayuki Itabashi | 2001 | Gastric Cancer2001,,1: | 1 |
| 18 | Inverse relationship between platelet Akt activity and hippocampal atrophy:A pilot case-control study in patients with diabetes mellitus显示文摘BACKGROUND Akt plays diverse roles in humans.It is involved in the pathogenesis of type 2 diabetes mellitus(T2DM),which is caused by insulin resistance.Akt also plays a vital role in human platelet activation.Furthermore,the hippocampus is closely associated with memory and learning,and a decrease in hippocampal volume is reportedly associated with an insulin-resistant phenotype in T2DM patients without dementia.AIM To investigate the relationship between Akt phosphorylation in unstimulated platelets and the hippocampal volume in T2DM patients.METHODS Platelet-rich plasma(PRP)was prepared from the venous blood of patients with T2DM or age-matched controls.The pellet lysate of the centrifuged PRP was subjected to western blotting to analyse the phosphorylation of Akt,p38 mitogen-activated protein(MAP)kinase and glyceraldehyde 3-phosphate dehydrogenase(GAPDH).Phosphorylation levels were quantified by densitometric analysis.Hippocampal volume was analysed using a voxel-based specific regional analysis system for Alzheimer’s disease on magnetic resonance imaging,which proposes the Z-score as a parameter that reflects hippocampal volume.RESULTS The levels of phosphorylated Akt corrected with phosphorylated p38 MAP kinase were inversely correlated with the Z-scores in the T2DM subjects,whereas the levels of phosphorylated Akt corrected with GAPDH were not.However,this relationship was not observed in the control patients.CONCLUSION These results suggest that an inverse relationship may exist between platelet Akt activation and hippocampal atrophy in T2DM patients.Our findings provide insight into the molecular mechanisms underlying T2DM hippocampal atrophy. | Haruhiko Tokuda Takamitsu Hori Daisuke Mizutani Tomoyuki Hioki Kumi Kojima Takashi Onuma Yukiko Enomoto Tomoaki Doi Rie Matsushima-Nishiwaki Shinji Ogura Hiroki Iida Toru Iwama Takashi Sakurai Osamu Kozawa | 2024 | World Journal of Clinical Cases2024,12,2: | 0 |