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| 1 | Comparing the Diagnostic Criteria for Gestational Diabetes Mellitus of World Health Organization 2013 with 1999 in Chinese Population显示文摘INTRODUCTION Gestational diabetes mellitus (GDM) was earlier defined as 'hyperglycemia first recognized during pregnancy' and has more recently been described by American Diabetes Association (ADA) (2012) as diabetes diagnosed during pregnancy that is not clearly overt diabetes.[1] The hyperglycemia and adverse pregnancy outcomes study (HAPO) demonstrated that the risk of adverse maternal,fetal,and neonatal outcomes continuously increase as a function of maternal glycemia at 24-28 weeks,even within ranges previously considered normal for pregnancy.[2] After reviewing the results of the HAPO study,many international diabetes study groups,including the International Association of Diabetes and Pregnancy Study Groups and ADA have adopted the 75 g oral glucose tolerance test (OGTT) at 24-28 weeks as a screening and diagnostic test and defined new cut-off values for GDM diagnosis.The Ministry of Health of China published the criteria for GDM,that is the same as the ADA criteria on July 1,2011.World Health Organization (WHO) has recommended the 75 g OGTT with different cut-offvalues as a diagnostic test since 1999,changed its recommendation on 2013.In Hongkong and Yunnan province in China,most hospital adopted the WHO 1999 criteria,nevertheless,there is no evidence of multicenter and large sample to show that the GDM population within the same ethnic group diagnosed by the new WHO criteria matches those diagnosed by the old one and consistency between the two criteria has not been reported.Thus,we conducted this study to analyze the two criteria in Chinese pregnant women. | Weiwei Zhu Huixia Yang Yumei Wei Zilian Wang Xuelan Li Hairong Wu Nan Li Meihua Zhang Xinghui Liu Hua Zhang Yunhui Wang Jianmin Niu Yujie Gan Liruo Zhong Yunfeng Wang Anil Kapur | 2015 | Chinese Medical Journal2015，，1： | 42 |
| 2 | Optimization of Agrobacterium tumefaciens-Mediated Transformation Systems in Tea Plant(Camellia sinensis)显示文摘In this study, an efficient plant regeneration protocol in vitro and transformation by Agrobacterium-mediated method of Camellia sinensis was achieved, which would lay the foundation for genetic improvement of tea plant by genetic engineering technology. The cotyledon callus of C.sinensis were used as the receptors for transformation by Agrobacterium tumefaciens EHA105 containing PS1aG-3. Some factors which affected the result of Agrobacterium-mediated transformation of C. sinensis were studied on the basis of GUS transient expression system. The optimum system of Agrobacterium-mediated transformation was that the cotyledon callus were pre-cultured for 3 d, and then infected by EHA105 for 15 min followed by 3 d co-culture in the dark on the YEB medium containing 150 μmol·L^(-1) acetosyringone(AS). The transient expression rate of GUS gene was 62.6%. After being delayed selective culture for 3 d, infected callus were transferred into the differentiation medium and the root induction medium both of which were supplemented with 100 mg·L^(-1) spectinomycin, and then resistant seedlings of C. sinensis were obtained. The conversion rate was 3.6%. | LV Qianru CHEN Changsong XU Yijuan HU Shunkai WANG Le SUN Kang CHEN Xuan LI Xinghui | 2017 | Horticultural Plant Journal2017，3，3： | 9 |
| 3 | Spatial and vertical variations of perfluoroalkyl substances in sediments of the Haihe River,China显示文摘The levels of six perfluoroalkyl substances(PFASs) in surface sediment and their vertical variations in dated sediment cores from the Haihe River were investigated; studied substances included perfluorooctanoic acid(PFOA),perfluorononanoic acid(PFNA),perfluorooctane sulfonate(PFOS),perfluorodecanoic acid(PFDA),perfluoroundecanoic acid(PFUnA),and perfluorododecanoic acid(PFDoA). Results showed that the total PFAS concentration in surface sediment ranged between 0.52 and 16.33 ng/g dry weight(dw) with an average of3.47 ng/g dw,with PFOS and PFOA as the dominant PFASs. In general,the PFAS concentrations in the mainstream increased from the upper to the lower reaches,except that a drop occurred downstream of the Erdao dam. Although the PFASs in the sediment cores did not show a clear decreasing or increasing trend with depth,the three cores had a similar vertical variation.The PFAS levels were relatively low in the surface sediment,and reached the first high point at8–20 cm as a result of the wide use of PFASs from 1990 to 2000. After that the PFAS levels decreased,and then increased to a second high point at about 40–48 cm,which might be caused by the leaching of PFASs in sediment. Because PFASs have hydrophilic groups and relatively high solubility,the PFASs will transfer from the upper to lower layers of sediment when water infiltration occurs,leading to the fluctuation of PFAS levels in sediment cores. This study suggests that both the temporal variation of sources and transfer processes of PFASs in sediments are important factors influencing the vertical variation of PFASs in sediment cores. | Xiuli Zhao Xinghui Xia Shangwei Zhang Qiong Wu Xuejun Wang | 2014 | Journal of Environmental Sciences2014，26，8： | 8 |
| 4 | Effectiveness of ZiYin Xiehuo granules and Zishen Qinggan granules on partial precocious puberty in girls: a multicenter, randomized, single-blind, controlled trial显示文摘OBJECTIVE: To evaluate the effect of ZiYin Xiehuo granules(ZYXH) and Zishen Qinggan granules(ZSQG) on partial precocious puberty(PPP).METHODS: This was a multicenter, randomized, single-blind, positive-controlled trial. A total of 143 pa-tients were assigned to either the ZYXH group or the ZSQG group using a random number table. The ZYXH group received ZYXH three times daily for 6 months and the ZSQG group received ZSQG three times daily for 6 months. Mammary nucleus diameter; the results of uterus, ovarian, and maximum follicle measures; and Chinese medicine symptom pattern scores were compared at baseline and after 3 months and 6 months of treatment.RESULTS: After 3 months' treatment, there were no significant differences between the two groups in mammary nucleus index changes(left 3.4 ± 3.1 vs3.5 ± 3.1, P = 0.790; right 3.0 ± 2.9 vs 3.6 ± 3.0, P =0.719). The uterine volume in the ZYXH group was smaller than that in the ZSQG group(2.1 ± 1.6 vs2.6 ± 2.2, P = 0.006). There were no significant between-group differences in ovarian volume and maximum follicular diameter on either side(ovarian volume: left 1.2 ± 0.7 vs 1.3 ± 0.6, P = 0.8; right1.2 ± 0.7 vs 1.4 ± 1.1, P = 0.984; maximum follicular diameter: left 3.9 ± 1.7 vs 3.5 ± 2.2, P = 0.158; right3.5 ± 1.7 vs 3.9 ± 2.1, P = 0.314).CONCLUSION: ZYXH granules and ZSQG granules both affected the size of the mammary nucleus in girls with PPP, and improved Chinese medicine symptom patterns. ZYXH granules showed slight advantages over ZSQG granules in terms of the decrease in the size of the uterus, ovaries, and ovarian follicles. | Sun Wen Han Xinghui Wang Yonghong Yu Jian Yan Weili Zhao Jun Chen Weibin Xue Zheng | 2018 | Journal of Traditional Chinese Medicine2018，38，5： | 5 |
| 5 | Relationship between metabolic enzyme activities and bioaccumulation kinetics of PAHs in zebrafish(Danio rerio)显示文摘Many studies have investigated bioaccumulation and metabolism of polycyclic aromatic hydrocarbons(PAHs)in aquatic organisms.However,lack of studies investigated both processes simultaneously,and the interaction between these two processes is less understood so far.This study investigated the bioaccumulation kinetics of PAHs and metabolic enzyme activities,including total cytochrome P450(CYPs)and total superoxide dismutase(T-SOD),in zebrafish.Mature zebrafish were exposed to the mixture of phenanthrene and anthracene under constant concentration maintained by passive dosing systems for 16 days.The results showed that PAH concentrations in zebrafish experienced a peak value after exposure for 1.5 days,and then decreased gradually.The bioaccumulation equilibrium was achieved after exposure for 12 days.Both of the uptake rate constants(k_u)and the elimination rate constants(k_e)decreased after the peak value.The variation of PAH concentrations and metabolic enzyme activities in zebrafish had an interactive relationship.The activities of CYPs and T-SOD increased initially with the increase of PAH concentrations,but decreased to the lowest state when PAH concentrations reached the peak value.When the bioaccumulation equilibrium of PAHs was achieved,CYPs and T-SOD activities also reached the steady state.In general,CYPs and T-SOD activities were activated after exposure to PAHs.The decrease of PAH concentrations in zebrafish after the peak value may be attributed to the great drop of k_uand the variation of CYPs activities.This study suggests that an interactive relationship exists between bioaccumulation kinetics of PAHs and metabolic enzyme activities in aquatic organisms. | Haotian Wang Yayuan Li Xinghui Xia Xinyue Xiong | 2018 | Journal of Environmental Sciences2018，30，3： | 4 |
| 6 | Post-marketing safety surveillance and reevaluation of Motherwort injection:A clinical study of 10094 cases显示文摘OBJECTIVE:To investigate the safety profiles of Motherwort injection(MI).METHODS:A multi-center,prospective and drugderived hospital intensive monitoring method was conducted to assess the safety of MI in real world applications.This study was based on a very large population after the injection was approved and marketed in China.All patients using the injection in participating hospitals were monitored to determine the incidence,pattern,severity and outcome of associated adverse events.RESULTS:The post-marketing surveillance was performed in 10 094 female patients from April to December,2015.The incidence of adverse drug reactions(ADRs) was 0.79‰(8/10 094).Among the 8 patients,the reported adverse events mainly included systemic abnormalities,such as fever,chills and eyelid edema;skin and appendages disorders,such as pruritus and rash;gastrointestinal disorders,such as nausea,abdominal distension and pain;heart rate and rhythm disorders,such as palpitation and increased heart rate.All of these ADRs were mild in severity.CONCLUSION:In this study the ADRs incidence rate of MI is very low,which supports that it is generally safe for use in obstetric and gynecological diseases.However,the total number of 8 ADRs recorded over a relatively short time span seems limited,and the low number of reports could not represent an absolute guarantee of safety. | Cao Shan Zhang Wenhao Zhao Ziwei Heng Mingli Bu Huaien Wang Hongwu Liu Xinghui Wang Zhong Cai Yan Ma Yuyan Cui Shihong Deng Jihong Ding Guifeng Ding Yajuan Dong Linhong Duan Zhentao Fan Ling Fan Yang Fu Fen He Jing Ji Shuying Jin Lin Li Hong Li Hongying Liao Tao Lu Wei Luo Xiucui Lü Zhihui Ma Fengchun Ma Dafeng Shi Tianyun Sun Juying Sun Xiaotong Teng Hong Wang Jinhua Wang Ruihua Wang Ying Wang Zhengling Xi Jie Xu Minjuan Xu Zhihong Yan Qian Yang Cuirong Yang Yimei Yin Jie Yu Jinhua Yuan Wenjun Zhang Guanli Zhang Meihua Zhao Renfeng Zhong Yonghong Zhou Jian | 2018 | Journal of Traditional Chinese Medicine2018，38，4： | 4 |
| 7 | Rambutan-like hollow carbon spheres decorated with vacancy-rich nickel oxide for energy conversion and storage显示文摘Transition metal oxides hold great promise for lithium-ion batteries(LIBs)and electrocatalytic water splitting because of their high abundance and high energy density.However,designing and fabrication of efficient,stable,high power density electrode materials are challenging.Herein,we report rambutan-like hollow carbon spheres formed by carbon nanosheet decorated with nickel oxide(NiO)rich inmetal vacancies(denoted as h-NiO/C)as a bifunctional electrode material for LIBs and electrocatalytic oxygen evolution reaction(OER).When being used as the anode of LIBs,the h-NiO/C electrode shows a large initial capacity of 885mAh g−1,a robust stability with a high capacity of 817mAh g−1 after 400 cycles,and great rate capability with a high reversible capacity of 523mAh g−1 at 10Ag−1 after 600 cycles.Moreover,working as an OER electrocatalyst,the h-NiO/C electrode shows a small overpotential of 260mV at 10mAcm−2,a Tafel slope of 37.6mVdec−1 along with good stability.Our work offers a cost-effective method for the fabrication of efficient electrode for LIBs and OER. | Zixu Sun Xinghui Wang Hu Zhao See W.Koh Junyu Ge Yunxing Zhao Pingqi Gao Guangjin Wang Hong Li | 2020 | Carbon Energy2020，2，1： | 4 |
| 8 | Noncoding RNAs and Their Potential Therapeutic Applications in Tissue Engineering显示文摘Tissue engineering is a relatively new but rapidly developing field in the medical sciences. Noncoding RNAs(ncRNAs) are functional RNA molecules without a protein-coding function; they can regulate cellular behavior and change the biological milieu of the tissue. The application of ncRNAs in tissue engineering is starting to attract increasing attention as a means of resolving a large number of unmet healthcare needs, although ncRNA-based approaches have not yet entered clinical practice. In-depth research on the regulation and delivery of ncRNAs may improve their application in tissue engineering.The aim of this review is: to outline essential ncRNAs that are related to tissue engineering for the repair and regeneration of nerve, skin, liver, vascular system, and muscle tissue; to discuss their regulation and delivery; and to anticipate their potential therapeutic applications. | Shiying Li Tianmei Qian Xinghui Wang Jie Liu Xiaosong Gu | 2017 | Engineering2017，3，1： | 4 |
| 9 | Missile aerodynamic design using reinforcement learning and transfer learning显示文摘Dear editor,Aerodynamic design is usually a time-consuming process of four steps [1]. First, an initial design profile is obtained with designer’s domain knowledge. Second, the design profile is represented as a CAD model using softwares such as Catia or UG.Third, a CAE software, such as ICEM or Hypermesh, is applied to generate corresponding meshes.At last, a computational fluid dynamics (CFD)software, such as Fluent or CFX, is used to calculate the performance. Therefore, only | Xinghui YAN Jihong ZHU Minchi KUANG Xiangyang WANG | 2018 | Science China(Information Sciences)2018，61，11： | 4 |
| 10 | Three-Probe Error Separation with Chromatic Confocal Sensors for Roundness Measurement显示文摘In this study,three-probe error separation was developed with three chromatic confocal displacement sensors for roundness measurement.Here,the harmonic suppression is discussed first to set suitable orientation angles among three sensors.Monte Carlo simulation is utilized to test the error separation and optimize the orientation angles and off-axial distance.The experimental setup is established using chromatic confocal sensors with a precise rotary platform.The experimental results show that the measured roundness with an orientation-angle combination of(0°,90.1°,and 178.6°)is much better than that of another nonoptimal selection(0°,90.4°,and 177.4°).The roundness error is only 0.7%between the proposed measurement system and an expensive ultraprecision roundness meter.Furthermore,it is proven that the eccentricity distance should be decreased as small as possible to improve the measurement accuracy.In sum,this paper proposes a feasible method for roundness measurement with reliable simulations,easily integrated sensors,and an ordinary precision rotary platform. | Jiao Bai Yingzuo Wang Xiaohao Wang Qian Zhou Kai Ni Xinghui Li | 2021 | Nanomanufacturing and Metrology2021，4，4： | 3 |
| 11 | Density functional theory study of the mechanism of the acid-catalyzed decarboxylation of pyrrole-2-carboxylic acid and mesitoic acid显示文摘The mechanisms of the acid-catalyzed decarboxylation of pyrrole-2-carboxylic acid and mesitoic acid have been investigated based on density functional theory calculations at the B3LYP/6-311G (d,p) level. A polarizable continuum model (PCM) has been established in order to evaluate the effects of solvents on these reactions. The results of the calculations indicate that the first step of the acid-catalyzed decarboxylation of the pyrrole-2-carboxylic acid has two possible pathways,that is,the proton of H3O+ attacks either the-carbon atom or the carboxyl oxygen atom. The subsequent process of forming a four-membered ring transition state is the rate-determining step. The activation energies of acid-catalyzed decarboxylation of pyrrole-2-carboxylic acid proceeding via attack at the-carbon atom and the carboxyl oxygen atom are determined to be 194.21 and 210.41 kJ/mol,respectively. The computational results show that both pathways are favored. However,for the reaction of mesitoic acid with H3O+,the reaction barrier for the former pathway is calculated to be 212.15 kJ/mol,whilst the latter pathway has a reaction barrier of 200.45 kJ/mol. Our computational results are consistent with the experimental observations of Mundle and Kluger. | ZHANG XingHui GENG ZhiYuan WANG YongCheng | 2011 | Science China Chemistry2011，54，5： | 3 |
| 12 | Three-dimensional knotting of W_(17)O_(47)@PEDOT:PSS nanowires enables high-performance flexible cathode for dual-functional electrochromic and electrochemical device显示文摘An efficient integration of electrochromic and electrochemical devices into one flexible entity enables both energy storage and energy-saving dual-functionalities.For this purpose,achieving both high electrochromic and electrochemical performance is the key aspect.Herein,a new 3D architecture is successfully made by knotting W_(17)O_(47)@PEDOT(poly(3,4-ethylenedioxythiophene)):PSS(poly(styrenesulfonate))nanowires with NaWO_(3)nanoknots,and interestingly,the 3D W_(17)O_(47)/(NaWO_(3)-knots)@PEDOT:PSS cathode thus-made simultaneously exhibits a large optical modulation(79.7%at 633 nm),an ultra-long cycling life(76%of original optical modulation retained after 12400 cycles),and a high areal capacitance(55.1 mF cm^(-2)at 0.1 mA cm^(-2)).Our density functional theory(DFT)calculations demonstrate that the much improved dual-functional performance is correlated to the raised electronic conductivity and ion adsorption at the W_(17)O_(47)/(NaWO_(3)nanoknots)interface,together with the ion adsorption of PEDOT:PSS in the 3D-knotted architecture.As a proof-of-concept application,different-sized flexible dual-functional electrochromic/electrochemical devices(FDEDs)were assembled and investigated for various application scenarios,including a smart window(15 cm×10 cm),a wearable wristband(20 cm×2.5 cm),and a smart eyeglass.The smart window made of the FDED enables a large temperature difference of 27.6℃ confirm-tested in model houses,where the energy source also powers three light-emitting diodes(LEDs).The understandings of the key governing principles in the electrodes and dual-functionalities provide a timely foundation for the new generation flexible multifunctional devices. | Qi Zhao Jinkai Wang Xinghui Ai Yujuan Duan Zhenghui Pan Shaorong Xie John Wang Yanfeng Gao | 2022 | InfoMat2022，4，4： | 2 |
| 13 | Polarized holographic lithography system for high-uniformity microscale patterning with periodic tunability显示文摘Periodic microscale array structures play an important role in diverse applications involving photonic crystals and diffraction gratings.A polarized holographic lithography system is proposed for patterning high-uniformity microscale two-dimensional crossed-grating structures with periodic tunability.Orthogonal two-axis Lloyd’s mirror interference and polarization modulation produce three sub-beams,enabling the formation of two-dimensional crossed-grating patterns with wavelength-comparable periods by a single exposure.The two-dimensional-pattern period can also be flexibly tuned by adjusting the interferometer spatial positioning.Polarization states of three sub-beams,defining the uniformity of the interference fringes,are modulated at their initial-polarization states based on a strict full polarization tracing model in a three-dimensional space.A polarization modulation model is established considering two conditions of eliminating the unexpected interference and providing the desired identical interference intensities.The proposed system is a promising approach for fabricating high-uniformity two-dimensional crossed gratings with a relatively large grating period range of 500–1500 nm.Moreover,our rapid and stable approach for patterning period-tunable two-dimensional-array microstructures with high uniformity could be applicable to other multibeam interference lithography techniques. | Gaopeng Xue Qihang Zhai Haiou Lu Qian Zhou Kai Ni Liyu Lin Xiaohao Wang Xinghui Li | 2021 | Microsystems & Nanoengineering2021，7，2： | 2 |
| 14 | Quantum chemical study on the abstraction reaction of alkylidenegermylene with oxirane and thiirane显示文摘The mechanisms of theion reaction of alkylidenegermylene with oxirane and thiirane have been characterized detail in using density functional theory, as well as ab initio method, including geometry optimization and vibrational analysis for the involved stationary points on the potential energy surface. Energies were calculated by CCSD(T)/6-311G(d)//B3LYP/6-311G(d,p) method for the involved conformations. The results show that the reaction pathways for both reactions consist of two ways: (1) the reactants can yield bent products (P1; P4) by syn-isomers; (2) the reactants can also yield three-membered products (P2; P5) by anti-isomers, which then further react with oxirane and thiirane to form the ultimate products (P3-1, P3-2; P6). Furthermore, a comparison with alkylidenecarbene, oxirane, and thiirane was done. | GENG ZhiYuan YAO Kun WANG YongCheng FANG Ran ZHANG XingHui JIA BaoLi | 2007 | Science China Chemistry2007，50，3： | 2 |
| 15 | Major element chemistry of the Changjiang (Yangtze River) 显示文摘 | Chen Jingsheng Wang Feiyue Xia Xinghui Zhang Litian | 2002 | Chem Geol2002，187，34： | 1 |
| 16 | N/S co-doped carbon nanosheet bundles as high-capacity anode for potassium-ion battery显示文摘Potassium-ion batteries(PIBs)are of academic and economic significance,but still limited by the lack of highly active electrode materials for de-/intercalation of large-radius K ions.Herein,an interconnected nitrogen/sulfur co-doped carbon nanosheep bundle(N/S-CSB)was proposed as the potassium ions storage material.The rich co-doping of nitrogen/sulfur of N/S-CNB with three-dimensional hierarchical bundled array structure yields distensible interlayer spaces to buffer the volume expansion during K+insertion/extraction,offers more electrochemical active sites to obtain a high specific capacity,and provides efficient channels for fast ion/electron transports.Therefore,the N/S-CSB anode achieved high reversible specific capacity of 365 mAh/g obtained at 50 mA/g after 200 cycles with a coulombic efficiency(CE)close to 100%,high rate performance and long cycle stability.Moreover,the in-situ Raman spectra indicated outstanding reaction kinetics of as-prepared N/S-CSB anode. | Jinhui Cao Jiang Zhong Hanjiao Xu Shengyang Li Hongli Deng Tao Wang Ling Fan Xinghui Wang Lei Wang Jian Zhu Bingan Lu Xidong Duan | 2022 | Nano Research2022，15，3： | 1 |
| 17 | The n+n combined structure gas sensor based on burnable gases显示文摘 | Wang Yude Wu Xinghui Li Yanfeng | 2001 | Solid-state Electronics2001，45，： | 1 |
| 18 | All-Solid-State Thin-Film Lithium-Sulfur Batteries显示文摘Lithium-sulfur(Li-S)system coupled with thin-film solid electrolyte as a novel high-energy micro-battery has enormous potential for complementing embedded energy harvesters to enable the autonomy of the Internet of Things microdevice.However,the volatility in high vacuum and intrinsic sluggish kinetics of S hinder researchers from empirically integrating it into allsolid-state thin-film batteries,leading to inexperience in fabricating all-solid-state thin-film Li-S batteries(TFLSBs).Herein,for the first time,TFLSBs have been successfully constructed by stacking vertical graphene nanosheets-Li2S(VGsLi2S)composite thin-film cathode,lithium-phosphorous-oxynitride(LiPON)thin-film solid electrolyte,and Li metal anode.Fundamentally eliminating Lipolysulfide shuttle effect and maintaining a stable VGs-Li2S/LiPON interface upon prolonged cycles have been well identified by employing the solid-state Li-S system with an“unlimited Li”reservoir,which exhibits excellent longterm cycling stability with a capacity retention of 81%for 3,000 cycles,and an exceptional high temperature tolerance up to 60℃.More impressively,VGs-Li2S-based TFLSBs with evaporated-Li thin-film anode also demonstrate outstanding cycling performance over 500 cycles with a high Coulombic efficiency of 99.71%.Collectively,this study presents a new development strategy for secure and high-performance rechargeable all-solid-state thin-film batteries. | Renming Deng Bingyuan Ke Yonghui Xie Shoulin Cheng Congcong Zhang Hong Zhang Bingan Lu Xinghui Wang | 2023 | Nano-Micro Letters2023，15，5： | 1 |
| 19 | Hydrothermal synthesis of Fe3O4 nanoparticles and its application in lithium ion battery显示文摘 | Ni Shibing Wang Xinghui Zhou Guo | 2009 | Materials Letters2009，63，30： | 1 |
| 20 | 5-20 MeV proton irradiation effects on GaAs/Ge solar cells for space use显示文摘 | Wang Rong Guo Zengliang Zhang Xinghui | 2003 | Solar Energy Materials & Solar Cells2003，77，4： | 1 |
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