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| 1 | Runoff Responses to Climate Change in Arid Region of Northwestern China During 1960-2010显示文摘Based on runoff, air temperature, and precipitation data from 1960 to 2010, the effects of climate change on water resources in the arid region of the northwestern China were investigated. The long-term trends of hydroclimatic variables were studied by using both Mann-Kendall test and distributed-free cumulative sum (CUSUM) chart test. Results indicate that the mean annual air temperature increases significantly from 1960 to 2010. The annual precipitation exhibits an increasing trend, especially in the south slope of the Tianshan Mountains and the North Uygur Autonomous Region of Xinjiang in the study period. Step changes occur in 1988 in the mean annual air temperature time series and in 1991 in the precipitation time series. The runoff in different basins shows different trends, i.e., significantly increasing in the Kaidu River, the Aksu River and the Shule River, and decreasing in the Shiyang River. Correlation analysis reveals that the runoff in the North Xinjiang (i.e., the Weigan River, the Heihe River, and the Shiyang River) has a strong positive relationship with rainfall, while that in the south slope of the Tianshan Mountains, the middle section of the north slope of the Tianshan Mountains and the Shule River has a strong positive relationship with air temperature. The trends of runoff have strong negative correlations with glacier coverage and the proportion of glacier water in runoff. From the late 1980s, the climate has become warm and wet in the arid region of the northwestern China. The change in runoff is interacted with air temperature, precipitation and glacier coverage. The results show that streamflow in the arid region of the northwestern China is sensitive to climate change, which can be used as a reference for regional water resource assessment and management. | WANG Huaijun CHEN Yaning LI Weihong DENG Haijun | 2013 | Chinese Geographical Science2013，23，3： | 11 |
| 2 | Remote Sensing Monitoring of Tobacco Field Based on Phenological Characteristics and Time Series Image―A Case Study of Chengjiang County, Yunnan Province, China显示文摘Using three-phase remote sensing images of China-Brazil Earth Resources Satellite 02B (CBERS02B) and Landsat-5 TM, tobacco field was extracted by the analysis of time series image based on the different phenological characteristics between tobacco and other crops. The spectral characteristics of tobacco and corn in luxuriant growth stage are very similar, which makes them difficult to be distinguished using a single-phase remote sensing image. Field film after tobacco seedlings transplanting can be used as significant sign to identify tobacco. Remote sensing interpre- tation map based on the fusion image of TM and CBERS02B's High-Resolution (HR) camera image was used as stan- dard reference material to evaluate the classification accuracy of Spectral Angle Mapper (SAM) and Maximum Like- lihood Classifier (MLC) for time series image based on full samples test method. SAM has higher classification accu- racy and stability than MLC in dealing with time series image. The accuracy and Kappa of tobacco coverage extracted by SAM are 83.4% and 0.692 respectively, which can achieve the accuracy required by tobacco coverage measurement in a large area. | PENG Guangxiong DENG Lei CUI Weihong MING Tao SHEN Wei | 2009 | Chinese Geographical Science2009，19，2： | 8 |
| 3 | Multiplex genome editing using a dCas9-cytidine deaminase fusion in Streptomyces显示文摘CRISPR/Cas-mediated genome editing has greatly facilitated the study of gene function in Streptomyces. However, it could not be efficiently employed in streptomycetes with low homologous recombination(HR) ability. Here, a deaminase-assisted base editor d Cas9-CDA-ULstr was developed in Streptomyces, which comprises the nuclease-deficient Cas9(dCas9), the cytidine deaminase from Petromyzon marinus(PmCDA1), the uracil DNA glycosylase inhibitor(UGI) and the protein degradation tag(LVA tag). Using d Cas9-CDA-ULstr , we achieved single-, double-and triple-point mutations(cytosine-to-thymine substitutions)at target sites in Streptomyces coelicolor with efficiency up to 100%, 60% and 20%, respectively. This base editor was also demonstrated to be highly efficient for base editing in the industrial strain, Streptomyces rapamycinicus, which produces the immunosuppressive agent rapamycin. Compared with base editors derived from the cytidine deaminase rAPOBEC1, the PmCDA1-assisted base editor dCas9-CDA-ULstr could edit cytosines preceded by guanosines with high efficiency, which is a great advantage for editing Streptomyces genomes(with high GC content). Collectively, the base editor dCas9-CDA-ULstr could be employed for efficient multiplex genome editing in Streptomyces. Since the d Cas9-CDA-ULstr -based genome editing is independent of HR-mediated DNA repair, we believe this technology will greatly facilitate functional genome research and metabolic engineering in Streptomyces strains with weak HR ability. | Yawei Zhao Jinzhong Tian Guosong Zheng Jun Chen Chuanwen Sun Zhongyi Yang Andrei A.Zimin Weihong Jiang Zixin Deng Zhijun Wang Yinhua Lu | 2020 | Science China(Life Sciences)2020，63，7： | 2 |
| 4 | Extended SRC: Un- dersampled Face Recognition via Intra-Class Variant Dic- tionary显示文摘 | Deng Weihong Hu Jiani Guo Jun | 2012 | IEEE Transactions on Pattern Analysis and Machine Intelligence2012，34，9： | 1 |
| 5 | Discriminative multi-metric learning for kinship verification显示文摘 | Yan Haibin Lu Jiwen Deng Weihong | 2014 | IEEE Transactions on Information Forensics and Security2014，9，7： | 1 |
| 6 | Extended SRC:Under sam- pled face recognition via infraclass variant dictionary 显示文摘 | Deng Weihong Hu Jiani Guo Jun | 2012 | IEEE transactions on pattern analysis and machine intelli- gence2012，34，9： | 1 |
| 7 | Extended SRC:Undersampled face recognition via intra-class variant dictionary显示文摘 | Deng Weihong Hu Jiani Guo Jun | 2012 | IEEE Transactions on Pattern Analysis and Machine Intelligence2012，34，9： | 1 |
| 8 | The small sample size problem of ICA:A comparative study and analysis显示文摘 | Deng Weihong Liu Yebin Hu Jiani | 2012 | Pattern Recognition2012，45，12： | 1 |
| 9 | Ro- bust, accurate and efficient face recognition from a single training image: A uniform pursuit ap- proach 显示文摘 | Deng Weihong Hu Jiani Guo Jun | 2010 | Pattern Recognition2010，43，5： | 1 |
| 10 | Locality preserving and global discriminant projection with prior information显示文摘 | ZHANG Honggang DENG Weihong GUO Jun | 2010 | Machine Vision and Applications2010，21，4： | 1 |
| 11 | Extended SRC:undersampled face recognition via intraclass variant dictionary显示文摘 | Deng Weihong Hu Jiani Guo Jun | 2012 | IEEE Trans on Pattern Analysis and Machine Intelligence2012，34，9： | 1 |
| 12 | Extended SRC:Undersampled face recognition via intraclass variant dictionary显示文摘 | Deng Weihong Hu Jiani Guo Jun | 2012 | IEEE Transactions on Pattern Analysis and Machine Intelligence2012，34，9： | 1 |
| 13 | Recommendations for the diagnosis and treatment of paroxysmal kinesigemc dyskinesia: an expert consensus in China显示文摘Paroxysmal dyskinesias are a group of neurological diseases characterized by intermittent episodes of involuntary movements with different causes.Paroxysmal kinesigenic dyskinesia(PKD)is the most common type of paroxysmal dyskinesia and can be divided into primary and secondary types based on the etiology.Clinically,PKD is characterized by recurrent and transient attacks of involuntary movements precipitated by a sudden voluntary action.The major cause of primary PKD is genetic abnormalities,and the inheritance pattern of PKD is mainly autosomal-dominant with incomplete penetrance.The proline-rich transmembrane protein 2(PRRT2)was the first identified causative gene of PKD,accounting for the majority of PKD cases worldwide.An increasing number of studies has revealed the clinical and genetic characteristics,as well as the underlying mechanisms of PKD.By seeking the views of domestic experts,we propose an expert consensus regarding the diagnosis and treatment of PKD to help establish standardized clinical evaluation and therapies for PKD.In this consensus,we review the clinical manifestations,etiology,clinical diagnostic criteria and therapeutic recommendations for PKD,and results of genetic analyses in PKD patients performed in domestic hospitals. | Li Cao Xiaojun Huang Ning Wang Zhiying Wu Cheng Zhang Weihong Gu Shuyan Cong Jianhua Ma Ling Wei Yanchun Deng Qi Fang Qi Niu Jin Wang Zhaoxia Wang You Yin Jinyong Tian Shufen Tian Hongyan Bi Hong Jiang Xiaorong Liu Yang Lu Meizhen Sun Jianjun Wu Erhe Xu Tao Chen Tao Chen Xu Chen Wei Li Shujian Li Qinghua Li Xiaonan Song Ying Tang Ping Yang Yun Yang Min Zhang Xiong Zhang Yuhu Zhang Ruxu Zhang Yi Ouyang Jintai Yu Quanzhong Hu Qing Ke Yuanrong Yao Zhe Zhao Xiuhe Zhao Guohua Zhao Furu Liang Nan Cheng Jianhong Han Rong Peng Shengdi Chen Beisha Tang | 2021 | Translational Neurodegeneration2021，10，1： | 1 |
| 14 | Transform- invariant PCA: a unified approach to fully automatic face alignment, representation, and recognition 显示文摘 | Deng Weihong Hu Jiani Lu Jiwen | 2014 | IEEN Transactions on Pattern Analysis and Machine Intelligence2014，36，6： | 1 |
| 15 | Nucleic acids analysis显示文摘Nucleic acids are natural biopolymers of nucleotides that store, encode, transmit and express genetic information, which play central roles in diverse cellular events and diseases in living things. The analysis of nucleic acids and nucleic acids-based analysis have been widely applied in biological studies, clinical diagnosis, environmental analysis, food safety and forensic analysis.During the past decades, the field of nucleic acids analysis has been rapidly advancing with many technological breakthroughs.In this review, we focus on the methods developed for analyzing nucleic acids, nucleic acids-based analysis, device for nucleic acids analysis, and applications of nucleic acids analysis. The representative strategies for the development of new nucleic acids analysis in this field are summarized, and key advantages and possible limitations are discussed. Finally, a brief perspective on existing challenges and further research development is provided. | Yongxi Zhao Xiaolei Zuo Qian Li Feng Chen Yan-Ru Chen Jinqi Deng Da Han Changlong Hao Fujian Huang Yanyi Huang Guoliang Ke Hua Kuang Fan Li Jiang Li Min Li Na Li Zhenyu Lin Dingbin Liu Juewen Liu Libing Liu Xiaoguo Liu Chunhua Lu Fang Luo Xiuhai Mao Jiashu Sun Bo Tang Fei Wang Jianbin Wang Lihua Wang Shu Wang Lingling Wu Zai-Sheng Wu Fan Xia Chuanlai Xu Yang Yang Bi-Feng Yuan Quan Yuan Chao Zhang Zhi Zhu Chaoyong Yang Xiao-Bing Zhang Huanghao Yang Weihong Tan Chunhai Fan | 2021 | Science China Chemistry2021，64，2： | 1 |
| 16 | Comments on globally maximizing,locally minimizing:unsupervised discriminant projection with applications to face and palm biometrics显示文摘 | Deng Weihong Hu Jiani Guo Jun | 2008 | IEEE Transactions on Pattern Analysis and Machine Intelligence2008，30，8： | 1 |
| 17 | A Magnetocatalytic Propelled Cobalt-Platinum@Graphene Navigator for Enhanced Tumor Penetration and Theranostics显示文摘Complex biological environments and multiple physiological barriers significantly impede efficient accumulation and penetration of nanomaterials within tumor tissue for therapy.In situ energy conversion of nanomotors features autonomous movements and improves cancer treatment.However,one of the key challenges is to prepare nanomotors with an adequately small size,good biocompatibility,and precise positioning.Herein,we demonstrate a simple,ultrasmall,versatile,and real-time motion guidance strategy for magnetocatalytic CoPt@graphene navigators(MCGNs)that can enable highly efficient propulsion in the presence of H_(2)O_(2) or magnetic actuation.MCGNs act as highly diffusive delivery vehicles to promote tumor tissue targeting,and the amount of drug in the tumor was three times than without navigation.By engaging movements powered through in situ energy conversion,MCGNs gain considerable propulsion to penetrate a cell’s membrane and enhance intracellular delivery. | Liang Zhang Qian Dong Hui Zhang Jieqiong Xu Shen Wang Lufeng Zhang Wentao Tang Zhaoqian Li Xin Xia Xinqi Cai Shengkai Li Ruizi Peng Zhengyu Deng Michael JDonovan Long Chen Zhuo Chen Weihong Tan | 2022 | CCS Chemistry2022，4，7： | 1 |
| 18 | Study Progress of Traditional Chinese Massage Treatment of Lumbar Disc Herniation显示文摘 | Qing Lan Weihong Deng | 2014 | Frontier and Future Development of Information Technology in Medicine and Education2014，，269： | 1 |
| 19 | Fourier Locally Linear Soft Constrained MACE for facial landmark localization显示文摘 | Wenming Yang Xiang Sun Weihong Deng Chi Zhang Qingmin Liao | 2016 | CAAI Transactions on Intelligence Technology2016，1，3： | 1 |
| 20 | Extended SRC: undersampled face recognition via intraclass variant dictionary显示文摘 | Deng Weihong Hu Jiani Guo Jun | 2012 | IEEE Transactions on Pattern Analysis and Machine Intelligence2012，34，9： | 1 |
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