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| 1 | Novel cotton homeobox gene and its expression profiling in root development and in response to stresses and phytohormones显示文摘Homeodomain 白氨酸拉链(HD 压缩) 蛋白质是涉及植物开发的 transcriptional 因素。在这研究,一 cDNA 克隆(Gossypium hirsutum homeobox1,指明的 GhHB1 ) 编码 HD 压缩蛋白质从一个棉花根 cDNA 图书馆被孤立。GhHB1 cDNA 是在长度的 1132 bp,包括 828 bp 与 275 氨基酸编码肽的开的读框架,和 5'-/3'-untranslated 区域。包含 homeodomain 和一个充满白氨酸的拉链主题的预言的 GhHB1 蛋白质与另外的植物 HD 压缩蛋白质分享相对高的身份。用量的即时 RT-PCR 的分析显示 GhHB1 基因主要在根和胚轴被表示。而且, GhHB1 抄本大部分在早根开发被积累,并且显著地减少了,建议基因可能在根的早开发工作很,根推进的底层发展了。在有 1% NaCl 的处理下面, GhHB1 基因的表示水平戏剧性地在根被增加。同样,在根的 GhHB1 活动由 abscisic 是起来调整的。这些结果暗示 GhHB1 可能响应盐应力并且到 abscisic 发信号起一个重要作用。 | Yongxiang Ni Xiulan Wang Dengdi Li Yajie Wu Wenliang Xu Xuebao Li | 2008 | Acta Biochimica et Biophysica Sinica2008，40，1： | 12 |
| 2 | Sox2 enhances the tumorigenicity and chemoresistance of cancer stem-like cells derived from gastric cancer显示文摘Gastric cancer stem-like cells(GCSCs) have been identified to possess the ability of self-renewal and tumor initi-ation.However,the mechanisms involved remain largely unknown.Here,we isolated and characterized the GCSCs by side population(SP) sorting procedure and cultured sphere cells(SC) from human gastric cancer cell lines SGC-7901,BGC-823,MGC-803,HGC-27 and MKN-28.The sorting and culture assay revealed that SP cells proliferated in an asymmetric division manner.In addition,SP cells exhibited a higher potential of spheroid colony formation and greater drug resistance than non-SP cells(NSP).Moreover,the SC were found with enhanced capabilities of drug resistance in vitro and tumorigenicity in vivo.Sox2 mRNA and protein was highly and significantly overex-pressed in the SP cells and SC.Importantly,downregulation of Sox2 with siRNA obviously reduced spheroid colony formation and doxorubicin efflux,as well as increased apoptosis rate in sphere cells in vitro and suppressed tumori-genicity in vivo.These results suggest that both SP cells and cultured SC enrich with GCSCs and that Sox2 plays a pivotal role in sustaining stem cell properties and might be a potential target for gastric cancer therapy. | Tian Tian Yajie Zhang Shouyu Wang Jianwei Zhou Shan Xu | 2012 | The Journal of Biomedical Research2012，26，5： | 11 |
| 3 | Autofluorescence of MDA-modified proteins as an in vitro and in vivo probe in oxidative stress analysis显示文摘 | Qiang, Min Xu, Yajie Lu, Yang He, Yingge Han, Chanshuai Liu, Ying He, Rongqiao | 2014 | Protein & Cell2014，5，6： | 11 |
| 4 | Identification of ferroptosis as a novel mechanism for antitumor activity of natural product derivative a2 in gastric cancer显示文摘Ferroptosis is a type of cell death accompanied by iron-dependent lipid peroxidation,thus stimulating ferroptosis may be a potential strategy for treating gastric cancer,therapeutic agents against which are urgently required.Jiyuan oridonin A(JDA) is a natural compound isolated from Jiyuan Rabdosia rubescens with anti-tumor activity,unclear anti-tumor mechanisms and limited water solubility hamper its clinical application.Here,we showed a2,a new JDA derivative,inhibited the growth of gastric cancer cells.Subsequently,we discovered for the first time that a2 induced ferroptosis.Importantly,compound a2 decreased GPX4 expression and overexpressing GPX4 antagonized the anti-proliferative activity of a2.Furthermore,we demonstrated that a2 caused ferrous iron accumulation through the autophagy pathway,prevention of which rescued a2 induced ferrous iron elevation and cell growth inhibition.Moreover,a2 exhibited more potent anti-cancer activity than 5-fluorouracil in gastric canc er cell line-derived xenograft mice models.Patient-derived tumor xenograft models from different patients displayed varied sensitivity to a2,and GPX4 downregulation indicated the sensitivity of tumors to a2.Finally,a2 exhibited well pharmacokinetic characteristic s.Overall,our data suggest that inducing ferroptosis is the major mechanism mediating anti-tumor activity of a2,and a2 will hopefully serve as a promising compound for gastric cancer treatment. | Ying Liu Zan Song Yajie Liu Xubin Ma Wang Wang Yu Ke Yichao Xu Dequan Yu Hongmin Liu | 2021 | Acta Pharmaceutica Sinica B2021，11，6： | 10 |
| 5 | Design and fabrication of a SiN-Si dua卜layer optical phased array chip显示文摘A SiN-Si dual-layer optical phased array(OPA)chip is designed and fabricated.It combines the low loss of SiN with the excellent modulation performance of Si,which improves the performance of Si single-layer OPA.A novel optical antenna and an improved phase modulation method are also proposed,and a two dimensional scanning range of 96°×14°is achieved,which makes the OPA chip more practical. | PENGFEI WANG GUANGZHEN LUO YANG XU YAJIE LI YANMEI SU JIANBIN MA RUITING WANG ZHENGXIA YANG XULIANG ZHOU YEJIN ZHANG JIAOQING PAN | 2020 | Photonics Research2020，8，6： | 5 |
| 6 | Relocation of the Foreshocks and Aftershocks of the 2021 Ms 6.4 Yangbi Earthquake Sequence,Yunnan,China显示文摘An Ms 6.4 earthquake occurred in Yangbi,Yunnan,China on May 21,2021,which has obvious foreshock activity and abundant aftershocks.Based on the seismic observation data recorded by the Yunnan Seismic Network three days before and seven days after the mainshock,a doubledifference location method was used to relocate 2133 earthquakes of the Yangbi sequence.Aftershocks are mostly distributed to the southeast of the mainshock in a unilateral rupture pattern.This sequence exhibits a SE-trending linear alignment with a length of about 25 km,and most of the focal depth is above 12 km.Integrated with the seismic distribution and focal mechanism results,we infer that the strike of the seismogenic fault is about 140°,and dipping to the SW.The fault structure revealed by the seismic sequence is complex,with the NW segment exhibiting a steep dip and relatively simple structure of strike-slip rupture and the SE segment consisting of several branching ruptures.The Yangbi Earthquake is a typical foreshock-mainshock-aftershock sequence,and the mainshock is likely triggered by the largest foreshock.This earthquake occurred in the boundary between high-and lowvelocity anomalous zone,where is susceptible to generate large earthquakes. | Ting Yang Boren Li Lihua Fang Youjin Su Yusheng Zhong Jingqiong Yang Min Qin Yaji Xu | 2022 | Journal of Earth Science2022，33，4： | 5 |
| 7 | Exosomal HOTAIR promotes proliferation, migration and invasion of lung cancer by sponging miR-203显示文摘Dear Editor,Lung cancer is one of the most common causes of cancerrelated deaths worldwide.Despite great progress in the development of lung cancer treatments,the prognoses of patients with advanced stage cancer remains poor(Torre et al.,2015). | Chengcheng Zhang Lisha Xu Guoying Deng Yajie Ding Ke Bi Hansong Jin Jixin Shu Jia Yang Haibin Deng Zhongqi Wang Yin Wang | 2020 | Science China(Life Sciences)2020，63，8： | 4 |
| 8 | High-end equipment development task decomposition and scheme selection method显示文摘Decomposition of tasks and selection of optimal schemes are key procedures in high-end equipment development processes.However,such procedures are highly innovative,technology intensive,interdisciplinary,and multi-party engineering projects,making the decomposition and scheme selection more difficult and complicated than that in the development of ordinary equipment.In this study,we consider three factors,namely,functional structure,task granularity,and task feasibility in task decomposition of high-end equipment development.Based on the principles of systems engineering,a method of task decomposition is proposed.As for decomposition scheme selection,a method based on the superiority and inferiority ranking(SIR)method mixed information and multiple attribute decision making is proposed by considering attributes of scheme feasibility,uncertainty risk and task integration complexity.To verify the proposed method,development of a military electric vehicle is used as an example to demonstrate the calculation process. | XU Xiangqian YANG Kewei DOU Yajie ZHOU Zhexuan CHEN Ziyi TAN Yuejin | 2021 | Journal of Systems Engineering and Electronics2021，32，1： | 3 |
| 9 | NK cells play a significant role in immunosurveillance at the early stage of MLL-AF9 acute myeloid leukemia via CD226/CD155 interactions显示文摘Acute myeloid leukemia(AML) is an aggressive hematological malignancy, and the mechanism underlying immune system involvement in leukemia development is unclear. In the present study, we utilized a myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3(MLLT3/MLL-AF9)-induced AML mouse model with or without exposure to irradiation. We found that the leukemia cells could survive and expand in hosts with intact immune systems, whereas leukemia progression was accelerated in mice with impaired immune systems. Moreover, the leukemia cells escaped from host immunosurveillance via editing their immunogenicity, including the up-regulation of an inhibitory antigen(i.e., CD47) and the down-regulation of active antigens(i.e., CD86, CD54, retinoic acid early transcript(RAE), histocompatibility 2, D region locus b(H2-Db) and H2-Dd). Natural killer(NK) cells were activated in the early phase of AML progression, whereas T cells were stimulated in the late phase. Furthermore, NK cell depletion showed that NK cells were necessary for the elimination of leukemia cells in our AML mouse model. Notably, CD155/CD226 primarily mediated the interaction between NK cells and leukemia cells and contributed to the antitumor effects of NK cells during the early phase of AML. Clinical data from patients with diverse hematological malignancies showed that CD155 expression was decreased in hematological malignancies. Taken together, our results demonstrate that NK cells play a pivotal role in immunosurveillance against leukemia cells during the early stage of AML primarily through the CD226/CD155 interaction; however, NK cells are not sufficient to eliminate leukemia cells. | WANG YaJie CHEN Chen DONG Fang MA ShiHui XU Jing GONG YueMin CHENG Hui ZHOU Yuan CHENG Tao HAO Sha | 2015 | Science China(Life Sciences)2015，58，12： | 3 |
| 10 | Constructing quantum error correcting code via logic function显示文摘We present a systematic way to construct p-ary quantum error correcting codes using logic functions. As a consequence, for a given function with APC distance d′ 2, we can construct quantum codes with parameters ((n, K, d))p and gain a lower bound of K for all 2 d d′. The basic states of the constructed quantum codes can be stated and the sufficient conditions for saturating quantum Singleton bound are also discussed. We give quantum codes [[5, 1, 3]]p with p prime, [[6, 0, 4]], [[6, 2, 3]]p with p > 2 prime and [[2n, 2n - 2, 2]] as examples constructed in this way. | ZHONG ShuQin, MA Zhi & XU YaJie Zhengzhou Institute of Information Engineering, University of Information Engineering of China, Zhengzhou 450002, China | 2010 | Science China(Information Sciences)2010，53，3： | 3 |
| 11 | Correlation between Microstructure and Failure Mechanism of Hyriopsis cumingii Shell Structure显示文摘In nature,shells exhibit remarkable high toughness and impact resistance to the external load despite their brittle main constituent and simple hierarchical structure.In this work,the structure of the mussel shell Hyriopsis cumingii is analyzed by scanning electron micro scope and atomic force microscope,and the macro/micro compression and impact tests are perfonned.Results show that the shell has a three-layer structure:an outer cuticle layer,a prismatic layer,and a nacreous layer.The stiffer and load-dependent prismatic layer is conducive to improve the impact resistance of shell structure.Fracture morphology after failure proves that cracks are transgranularly propagated inside the prism and aragonite platelet,and the crack deflection and platelet pullout can effectively lock the stress,thereby eventually improving the impact-resistance and toughness of the shell. | Zhen Zhang Jun Zhu Yajie Chu Zhengnian Chen Shun Guo Junqiang Xu | 2019 | Journal of Bionic Engineering2019，16，5： | 2 |
| 12 | ON CLASSICAL BCH CODES AND QUANTUM BCH CODES显示文摘It is a regular way of constructing quantum error-correcting codes via codes with self-orthogonal property, and whether a classical Bose-Chaudhuri-Hocquenghem (BCH) code is self-orthogonal can be determined by its designed distance. In this paper, we give the sufficient and necessary condition for arbitrary classical BCH codes with self-orthogonal property through algorithms. We also give a better upper bound of the designed distance of a classical narrow-sense BCH code which contains its Euclidean dual. Besides these, we also give one algorithm to compute the dimension of these codes. The complexity of all algorithms is analyzed. Then the results can be applied to construct a series of quantum BCH codes via the famous CSS constructions. | Xu Yajie Ma Zhi Zhang Chunyuan | 2009 | Journal of Electronics(China)2009，26，1： | 2 |
| 13 | Random seismic noise attenuation by learning-type overcomplete dictionary based on K-singular value decomposition algorithm显示文摘The transformation of basic functions is one of the most commonly used techniques for seismic denoising,which employs sparse representation of seismic data in the transform domain. The choice of transform base functions has an influence on denoising results. We propose a learning-type overcomplete dictionary based on the K-singular value decomposition( K-SVD) algorithm. To construct the dictionary and use it for random seismic noise attenuation,we replace fixed transform base functions with an overcomplete redundancy function library. Owing to the adaptability to data characteristics,the learning-type dictionary describes essential data characteristics much better than conventional denoising methods. The sparsest representation of signals is obtained by the learning and training of seismic data. By comparing the same seismic data obtained using the learning-type overcomplete dictionary based on K-SVD and the data obtained using other denoising methods,we find that the learning-type overcomplete dictionary based on the K-SVD algorithm represents the seismic data more sparsely,effectively suppressing the random noise and improving the signal-to-noise ratio. | XU Dexin HAN Liguo LIU Dongyu WEI Yajie | 2016 | Global Geology2016，19，1： | 2 |
| 14 | Cobalt-doped Mn3O4 nanocrystals embedded in graphene nanosheets as a high-performance bifunctional oxygen electrocatalyst for rechargeable Zn–Air batteries显示文摘A non-noble-metal bifunctional catalyst with efficient and durable activity towards both the oxygen reduction reaction(ORR)and the oxygen evolution reaction(OER)is crucial to the development of rechargeable Zn-air batteries.Herein,a facile one-step hydrothermal method is reported for the synthesis of a high-performance bifunctional oxygen electrocatalyst,cobalt-doped Mn_(3)O_(4) nanocrystals supported on graphene nanosheets(Co–Mn_(3)O_(4)/G).Compare to pristine Mn_(3)O_(4),this Co–Mn_(3)O_(4)/G exhibits greatly enhanced electrocatalytic activity,delivering a halfwave potential of 0.866 V for the ORR and a low overpotential of 275 mV at 10 mA cm^(-2) for the OER.The zinc-air battery built with Co–Mn_(3)O_(4)/G shows a reduced charge–discharge voltage of 0.91 V at 10 mA cm^(-2),an power density of 115.24 mW cm^(-2) and excellent stability without any degradation after 945 cycles(315 h),outperforming the state-of-the-art Pt/C–Ir/C catalyst-based device. | Mengyang Dong Xu Liu Lixue Jiang Zhengju Zhu Yajie Shu Shan Chen Yuhai Dou Porun Liu Huajie Yin Huijun Zhao | 2020 | Green Energy & Environment2020，5，4： | 2 |
| 15 | Clinical characteristics and prognosis of triple-negative breast cancer显示文摘客观我们调查了临床的特征,和三元组否定的乳癌的预示的因素。130 个三元组否定的乳癌病人在临床的特征和预后上被考察的方法。所有情况是免疫组织化学决定的雌激素受体,孕酮受体,和 HER2/neu 的表示的缺乏。结果 17.1% 所有乳癌病人(774 个案例) 是三元组否定的乳癌,并且 68.9% 三元组否定的乳癌病人(91 个案例) 是绝经前的。53.8% 病人(71 个案例) 与 T2 尺寸有肿瘤,并且(52 个病人) 他们中的 39.4% 个有淋巴节点转移。没有淋巴节点转移,在有淋巴节点转移的病人的恶化的率在病人显然比那高(P = 0.001 ) 。后续的中部的时间是 63 个月。33 案例 relapsed 和 20 个病人死了。23 个病人有至少二机关转移。5 年的没有疾病、全面的幸存率是 73.8% 和 85.7% 。结论三元组否定的乳癌病人通常在治疗以后在 2 3 年里有多重远转移的高率。淋巴节点的地位是最重要的预示的因素。有淋巴节点转移的三元组否定的胸 caner 病人有差的预后。 | Hua Cao Maosheng Yan Shubin Wang Tao Zheng Ruilian Xu Yixin Chen Yajie Liu | 2009 | The Chinese-German Journal of Clinical Oncology2009，8，8： | 2 |
| 16 | In vivo fiber photometry of neural activity in response to optogenetically manipulated inputs in freely moving mice显示文摘In vito fber photometry is a powerful technique to analyze the dy namics of population neurons during fiunctional study of neuroscience.Here,we introduced a detailed protocol for fiber photometry-based calciun reording in freely moving mice,covering from virus injection,fiber stub insertion,optogenetical stimulation to data procurement and analysis.Furthemnore,we applied this protocol to explore neuronal activity of mice latenal-posterior(LP)thalaric nucleus in response to optogenetical stimulation of primary visual cortex(V1)neurons,and explore axon clusters activity of optogenetically evoked V1 neurons.Final confirmation of virus-based protein expression in V1 and precise fber insertion indicated that the surgery procedure of this protocol is reliable for functional calcium recording.The scripts for data analysis and some tips in our protocol are provided in details.Together,this protocol is simple,low-cost,and effective for neuronal activity detection by fiber photometry,which will hep neuroscience researchers to carry out fiunctional and behavioral study in vivo. | Liang Li Yajie Tang Leqiang Sun Khaista Rahman Kai Huang Weize Xu Jinsong Yu Jinxia Dai Gang Cao | 2017 | Journal of Innovative Optical Health Sciences2017，，5： | 1 |
| 17 | The Solar Upper Transition Region Imager(SUTRI)Onboard the SATech-01 Satellite显示文摘The Solar Upper Transition Region Imager(SUTRI)onboard the Space Advanced Technology demonstration satellite(SATech-01),which was launched to a Sun-synchronous orbit at a height of~500 km in 2022 July,aims to test the on-orbit performance of our newly developed Sc/Si multi-layer reflecting mirror and the 2k×2k EUV CMOS imaging camera and to take full-disk solar images at the Ne VII 46.5 nm spectral line with a filter width of~3 nm.SUTRI employs a Ritchey-Chrétien optical system with an aperture of 18 cm.The on-orbit observations show that SUTRI images have a field of view of~416×416 and a moderate spatial resolution of~8″without an image stabilization system.The normal cadence of SUTRI images is 30 s and the solar observation time is about16 hr each day because the earth eclipse time accounts for about 1/3 of SATech-01's orbit period.Approximately15 GB data is acquired each day and made available online after processing.SUTRI images are valuable as the Ne VII 46.5 nm line is formed at a temperature regime of~0.5 MK in the solar atmosphere,which has rarely been sampled by existing solar imagers.SUTRI observations will establish connections between structures in the lower solar atmosphere and corona,and advance our understanding of various types of solar activity such as flares,filament eruptions,coronal jets and coronal mass ejections. | Xianyong Bai Hui Tian Yuanyong Deng Zhanshan Wang Jianfeng Yang Xiaofeng Zhang Yonghe Zhang Runze Qi Nange Wang Yang Gao Jun Yu Chunling He Zhengxiang Shen Lun Shen Song Guo Zhenyong Hou Kaifan Ji Xingzi Bi Wei Duan Xiao Yang Jiaben Lin Ziyao Hu Qian Song Zihao Yang Yajie Chen Weidong Qiao Wei Ge Fu Li Lei Jin Jiawei He Xiaobo Chen Xiaocheng Zhu Junwang He Qi Shi Liu Liu Jinsong Li Dongxiao Xu Rui Liu Taijie Li Zhenggong Feng Yamin Wang Chengcheng Fan Shuo Liu Sifan Guo Zheng Sun Yuchuan Wu Haiyu Li Qi Yang Yuyang Ye Weichen Gu Jiali Wu Zhe Zhang Yue Yu Zeyi Ye Pengfeng Sheng Yifan Wang Wenbin Li Qiushi Huang Zhong Zhang | 2023 | Research in Astronomy and Astrophysics2023，23，6： | 1 |
| 18 | Current Situation Assessment of Urban Agriculture in Urban Planning in China显示文摘Urban agriculture (UA) is a spontaneous response to the increasing demand for food with the inevitable population expansion in urban areas. As a critical part of FAO’s Special Programme for Food Security (SPFS), UA has increasingly been considered as a significant contributor to food and nutrition security of urban residents all over the world. Thus, the central aim of this essay is to develop a better understanding of the current situation of UA in urban planning of China, and 6 categories of UA in China will be discussed, including Leisure Agriculture, Modern Agricultural Science and Technology Park, Community Supported Agriculture (CSA), Institutional garden and Edible landscape. And finally the paper tries to raise the awareness and drive innovation of UA in both theory and practice. | XU Yajie BAI Xue CHU Kaifeng | 2019 | Journal of Landscape Research2019，11，3： | 1 |
| 19 | Conducting polymeric nanoparticles synthesized in reverse micelles and their gas sensitivity based on quartz crystal microbalance 显示文摘 | Yang Yajie Jiang Yadong Xu Jianhua | 2007 | Polymer2007，48，15： | 1 |
| 20 | Towards magnetism in pigeon MagR: Iron- and iron-sulfur binding work indispensably and synergistically显示文摘The ability to navigate long distances is essential for many animals to locate shelter,food,and breeding grounds.Magnetic sense has evolved in various migratory and homing species to orient them based on the geomagnetic field.A highly conserved ironsulfur cluster assembly protein IscA is proposed as an animal magnetoreceptor(MagR).Iron-sulfur cluster binding is also suggested to play an essential role in MagR magnetism and is thus critical in animal magnetoreception.In the current study,we provide evidence for distinct iron binding and iron-sulfur cluster binding in MagR in pigeons,an avian species that relies on the geomagnetic field for navigation and homing.Pigeon MagR showed significantly higher total iron content from both iron-and ironsulfur binding.Y65 in pigeon MagR was shown to directly mediate mononuclear iron binding,and its mutation abolished iron-binding capacity of the protein.Surprisingly,both iron binding and iron-sulfur binding demonstrated synergistic effects,and thus appear to be integral and indispensable to pigeon MagR magnetism.These results not only extend our current understanding of the origin and complexity of MagR magnetism,but also imply a possible molecular explanation for the huge diversity in animal magnetoreception. | Yajie Zhou Tianyang Tong Mengke Wei Peng Zhang Fan Fei Xiujuan Zhou Zhen Guo Jing Zhang Huangtao Xu Lei Zhang Shun Wang Junfeng Wang Tiantian Cai Xin Zhang Can Xie | 2023 | Zoological Research2023，44，1： | 1 |
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