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| 1 | Improved algorithm of light scattering by a coated sphere显示文摘An efficient numerical algorithm for computing the light scattering by a coated sphere is proposed. The calculation of relevant functions by different recurrence algorithms is discussed. The new algorithm avoids the numerical difficulties, which give rise to significant errors encountered in practice by prior methods. Exemplifying results such as extinction efficiency, scattering efficiency, light scattering intensity as well as calculation speed are provided. The results show that this algorithm is efficient, fast, numerically stable and accurate. | Lei Liu Huarui Wang Bin Yu Yamin Xu Jianqi Shen | 2007 | China Particuology2007，5，3： | 5 |
| 2 | Chinese expert consensus on conversion therapy for hepatocellular carcinoma(2021 edition)显示文摘Recent advances in systemic and locoregional treatments for patients with unresectable or advanced hepatocellular carcinoma(HCC)have resulted in improved response rates.This has provided an opportunity for selected patients with initially unresectable HCC to achieve adequate tumor downstaging to undergo surgical resection,a‘conversion therapy’strategy.However,conversion therapy is a new approach to the treatment of HCC and its practice and treatment protocols are still being developed.Review the evidence for conversion therapy in HCC and develop consensus statements to guide clinical practice.Evidence review:Many research centers in China have accumulated significant experience implementing HCC conversion therapy.Preliminary findings and data have shown that conversion therapy represents an important strategy to maximize the survival of selected patients with intermediate stage to advanced HCC;however,there are still many urgent clinical and scientific challenges for this therapeutic strategy and its related fields.In order to summarize and learn from past experience and review current challenges,the Chinese Expert Consensus on Conversion Therapy for Hepatocellular Carcinoma(2021 Edition)was developed based on a review of preliminary experience and clinical data from Chinese and non-Chinese studies in this field and combined with recommendations for clinical practice.Sixteen consensus statements on the implementation of conversion therapy for HCC were developed.The statements generated in this review are based on a review of clinical evidence and real clinical experience and will help guide future progress in conversion therapy for patients with HCC. | Hui-Chuan Sun Jian Zhou Zheng Wang Xiufeng Liu Qing Xie Weidong Jia Ming Zhao Xinyu Bi Gong Li Xueli Bai Yuan Ji Li Xu Xiao-Dong Zhu Dousheng Bai Yajin Chen Yongjun Chen Chaoliu Dai Rongping Guo Wenzhi Guo Chunyi Hao Tao Huang Zhiyong Huang Deyu Li Gang Li Tao Li Xiangcheng Li Guangming Li Xiao Liang Jingfeng Liu Fubao Liu Shichun Lu Zheng Lu Weifu Lv Yilei Mao Guoliang Shao Yinghong Shi Tianqiang Song Guang Tan Yunqiang Tang Kaishan Tao Chidan Wan Guangyi Wang Lu Wang Shunxiang Wang Tianfu Wen Baocai Xing Bangde Xiang Sheng Yan Dinghua Yang Guowen Yin Tao Yin Zhenyu Yin Zhengping Yu Bixiang Zhang Jialin Zhang Shuijun Zhang Ti Zhang Yamin Zhang Yubao Zhang Aibin Zhang Haitao Zhao Ledu Zhou Wu Zhang Zhenyu Zhu Shukui Qin Feng Shen Xiujun Cai Gaojun Teng Jianqiang Cai Minshan Chen Qiang Li Lianxin Liu Weilin Wang Tingbo Liang Jiahong Dong Xiaoping Chen Xuehao Wang Shusen Zheng Jia Fan 无 | 2022 | Hepatobiliary Surgery and Nutrition2022，11，2： | 4 |
| 3 | Tailoring combinatorial lipid nanoparticles for intracellular delivery of nucleic acids, proteins,and drugs显示文摘Lipid nanoparticle(LNP)-based drug delivery systems have become the most clinically advanced non-viral delivery technology.LNPs can encapsulate and deliver a wide variety of bioactive agents,including the small molecule drugs,proteins and peptides,and nucleic acids.However,as the physicochemical properties of small-and macromolecular cargos can vary drastically,every LNP carrier system needs to be carefully tailored in order to deliver the cargo molecules in a safe and efficient manner.Our group applied the combinatorial library synthesis approach and in vitro and in vivo screening strategy for the development of LNP delivery systems for drug delivery.In this Review,we highlight our recent progress in the design,synthesis,characterization,evaluation,and optimization of combinatorial LNPs with novel structures and properties for the delivery of small-and macromolecular therapeutics both in vitro and in vivo.These delivery systems have enormous potentials for cancer therapy,antimicrobial applications,gene silencing,genome editing,and more.We also discuss the key challenges to the mechanistic study and clinical translation of new LNP-enabled therapeutics. | Yamin Li Zhongfeng Ye Hanyi Yang Qiaobing Xu | 2022 | Acta Pharmaceutica Sinica B2022，12，6： | 3 |
| 4 | Unveiling the Effects of Interchain Hydrogen Bonds on Solution Gelation and Mechanical Properties of Diarylfluorene-Based Semiconductor Polymers显示文摘The intrinsically rigid and limited strain of most conjugated polymers has encouraged us to optimize the extensible properties of conjugated polymers.Herein,learning from the hydrogen bonds in glucose,which were facilitated to the toughness enhancement of cellulose,we introduced interchain hydrogen bonds to polydiarylfluorene by amide-containing side chains.Through tuning the copolymerization ratio,we systematically investigated their influence on the hierarchical condensed structures,rheology behavior,tensile performances,and optoelectronic properties of conjugated polymers.Compared to the reference copolymers with a low ratio of amide units,copolymers with 30%and 40%amide units present a feature of the shearthinning process that resembled the non-Newtonian fluid,which was enabled by the interchain dynamic hydrogen bonds.Besides,we developed a practical and universal method for measuring the intrinsic mechanical properties of conjugated polymers.We demonstrated the significant impact of hydrogen bonds in solution gelation,material crystallization,and thin film stretchability.Impressively,the breaking elongation for P4 was even up to~30%,which confirmed the partially enhanced film ductility and toughness due to the increased amide groups.Furthermore,polymer light-emitting devices(PLEDs)based on these copolymers presented comparable performances and stable electroluminescence(EL).Thin films of these copolymers also exhibited random laser emission with the threshold as low as 0.52μJ/cm^(2),suggesting the wide prospective application in the field of flexible optoelectronic devices. | Lubing Bai Yamin Han Chen Sun Xiang An Chuanxin Wei Wei Liu Man Xu Lili Sun Ning Sun Mengna Yu He Zhang Qi Wei Chunxiang Xu Yingguo Yang Tianshi Qin Linghai Xie Jinyi Lin Wei Huang | 2020 | Research2020，，1： | 2 |
| 5 | Evolutionary analysis of Omicron variant BF.7 and BA.5.2 pandemic in China显示文摘On December 7,2022,China adjusted public health control measures,there have been widespread of SARS-CoV-2 infections in Chinese mainland.As the number of infected people increased,the mutation probability of SARS-CoV-2 is also raised.Therefore,it is of great importance to monitor SARS-CoV-2 variants and its mutations in China.In this current study,665 SARS-CoV-2 genomes from China deposited in the public database were used to analyze the proportion of different variants;to determine the composition of variants in China across different provinces;and analyze specific mutation frequency,focusing on 12 immune escape residues.The results showed that no new mutations were generated on the 12 immune escape residues.The evolutionary analysis of the BF.7 variant circulating in China showed that there is an independent evolutionary branch with unique mutation sites,officially named BF.7.14 by PANGO.This variant may have been imported from Russia to Inner Mongolia at the end of September 2022 and continued its spread in China.The evolutionary analysis of BA.5.2 variant shows that the variant is composed of two sub-variants,named BA.5.2.48 and BA.5.2.49 by PANGO,respectively.This variant may have been imported from abroad to Beijing at the beginning of September 2022 and formed two sub-variants after domestic transmission.Finally,this study showed that current epidemic variants in China were already circulating in other countries,and there were no additional mutations on immune escape residues that could pose a threat to other countries. | Yamin Sun Min Wang Wenchao Lin Wei Dong Jianguo Xu | 2023 | Journal of Biosafety and Biosecurity2023，5，1： | 2 |
| 6 | From China’s Heavy Precipitation in 2020 to a “Glocal” Hydrometeorological Solution for Flood Risk Prediction显示文摘The prolonged mei-yu/baiu system with anomalous precipitation in the year 2020 has swollen many rivers and lakes,caused flash flooding,urban flooding and landslides,and consistently wreaked havoc across large swathes of China,particularly in the Yangtze River basin.Significant precipitation and flooding anomalies have already been seen in magnitude and extension so far this year,which have been exerting much higher pressure on emergency responses in flood control and mitigation than in other years,even though a rainy season with multiple ongoing serious flood events in different provinces is not that uncommon in China.Instead of delving into the causes of the uniqueness of this year’s extreme precipitation-flooding situation,which certainly warrants in-depth exploration,in this article we provide a short view toward a more general hydrometeorological solution to this annual nationwide problem.A“glocal”(global to local)hydrometeorological solution for floods(GHS-F)is considered to be critical for better preparedness,mitigation,and management of different types of significant precipitation-caused flooding,which happen extensively almost every year in many countries such as China,India and the United States.Such a GHS-F model is necessary from both scientific and operational perspectives,with the strength in providing spatially consistent flood definitions and spatially distributed flood risk classification considering the heterogeneity in vulnerability and resilience across the entire domain.Priorities in the development of such a GHS-F are suggested,emphasizing the user’s requirements and needs according to practical experiences with various flood response agencies. | Huan WU Xiaomeng LI Guy J.-P.SCHUMANN Lorenzo ALFIERI Yun CHEN Hui XU Zhifang WU Hong LU Yamin HU Qiang ZHU Zhijun HUANG Weitian CHEN Ying HU | 2021 | Advances in Atmospheric Sciences2021，38，1： | 1 |
| 7 | Alkyl-chain branched effect on the aggregation and photophysical behavior of polydiarylfluorenes toward stable deep-blue electroluminescence and efficient amplified spontaneous emission显示文摘The control of the condensed superstructure of light-emitting conjugated polymers(LCPs)is a crucial factor to obtain high performance and stable organic optoelectronic devices.Side-chain engineering strategy is an effective platform to tune inter chain aggregation and photophysical behaviour of LCPs.Herein,we systematically investigated the alkyl-chain branched effecton the conformational transition and photophysical behaviour of polydiarylfluorenes toward efficient blue optoelectronic devices.The branched side chain will improve materials solubility to inhibit interchain aggregation in solution according to DLS and optical analysis,which is useful to obtain high quality film.Therefore,our branched PEODPF,POYDPF pristine film present high luminance efficiency of 36.1%and 39.6%,enhanced about 20%relative to that of PODPF.Compared to the liner-type sides'chain,these branched chains also suppress chain planarization and improve film morphological stability effectively.Interestingly,the branched polymer also had excellent stable amplified spontaneous emission(ASE)behaviour with low threshold(4.72μJ/cm2)and a center peak of 465 nm,even thermal annealing at 220℃in the air atmosphere.Therefore,side-chain branched strategy for LCPs is an effective means to control interchain aggregation,film morphology and photophysical property of LCPs. | Lili Sun Ning Sun Lubing Bai Xiang An Bin Liu Chen Sun Lixiang Fan Chuanxin Wei Yamin Han Mengna Yu Jinyi Lin Dan Lu Ning Wang Linghai Xie Kang Shen Xinwen Zhang Yanan Xu Juan Cabanillas-Gonzalez Wei Huang | 2019 | Chinese Chemical Letters2019，30，11： | 1 |
| 8 | The Solar Upper Transition Region Imager(SUTRI)Onboard the SATech-01 Satellite显示文摘The Solar Upper Transition Region Imager(SUTRI)onboard the Space Advanced Technology demonstration satellite(SATech-01),which was launched to a Sun-synchronous orbit at a height of~500 km in 2022 July,aims to test the on-orbit performance of our newly developed Sc/Si multi-layer reflecting mirror and the 2k×2k EUV CMOS imaging camera and to take full-disk solar images at the Ne VII 46.5 nm spectral line with a filter width of~3 nm.SUTRI employs a Ritchey-Chrétien optical system with an aperture of 18 cm.The on-orbit observations show that SUTRI images have a field of view of~416×416 and a moderate spatial resolution of~8″without an image stabilization system.The normal cadence of SUTRI images is 30 s and the solar observation time is about16 hr each day because the earth eclipse time accounts for about 1/3 of SATech-01's orbit period.Approximately15 GB data is acquired each day and made available online after processing.SUTRI images are valuable as the Ne VII 46.5 nm line is formed at a temperature regime of~0.5 MK in the solar atmosphere,which has rarely been sampled by existing solar imagers.SUTRI observations will establish connections between structures in the lower solar atmosphere and corona,and advance our understanding of various types of solar activity such as flares,filament eruptions,coronal jets and coronal mass ejections. | Xianyong Bai Hui Tian Yuanyong Deng Zhanshan Wang Jianfeng Yang Xiaofeng Zhang Yonghe Zhang Runze Qi Nange Wang Yang Gao Jun Yu Chunling He Zhengxiang Shen Lun Shen Song Guo Zhenyong Hou Kaifan Ji Xingzi Bi Wei Duan Xiao Yang Jiaben Lin Ziyao Hu Qian Song Zihao Yang Yajie Chen Weidong Qiao Wei Ge Fu Li Lei Jin Jiawei He Xiaobo Chen Xiaocheng Zhu Junwang He Qi Shi Liu Liu Jinsong Li Dongxiao Xu Rui Liu Taijie Li Zhenggong Feng Yamin Wang Chengcheng Fan Shuo Liu Sifan Guo Zheng Sun Yuchuan Wu Haiyu Li Qi Yang Yuyang Ye Weichen Gu Jiali Wu Zhe Zhang Yue Yu Zeyi Ye Pengfeng Sheng Yifan Wang Wenbin Li Qiushi Huang Zhong Zhang | 2023 | Research in Astronomy and Astrophysics2023，23，6： | 1 |
| 9 | De- sign and evaluation of gap-graded asphalt rubber mixtures 显示文摘 | Liu Yamin Han Sen Zhang Zhongjie Xu Ouming | 2012 | Materials & Design2012，，35： | 1 |
| 10 | An experimental and numerical study of flow and heat transfer in channels with pin fin-dimple and pin fin arrays显示文摘 | RAO Yu XU Yamin WAN Chaoyi | | 0，，04： | 1 |
| 11 | Impacts of road corridors on urban landscape pattern: a gradient analysis with changing grain size in Shanghai, China显示文摘 | Ming Zhu Jiangang Xu Nan Jiang Jianlong Li Yamin Fan | 2006 | Landscape Ecology2006，，5： | 1 |
| 12 | Unlinkable Secret Handshakes from Message Recovery Signature显示文摘 | Wen Yamin Zhang Fangguo Xu Lingling | 2010 | Chinese Journal of Electronics2010，19，4： | 1 |
| 13 | Origin and evolutionary analysis of the SARS-CoV-2 Omicron variant显示文摘The severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has evolved rapidly into new variants throughout the pandemic.The Omicron variant has more than 50 mutations when compared with the original wild-type strain and has been identified globally in numerous countries.In this report,we analyzed the mutational profiles of several variants,including the per-site mutation rate,to determine evolutionary relationships.The Omicron variant was found to have a unique mutation profile when compared with that of other SARS-CoV-2 variants,containing mutations that are rare in clinical samples.Moreover,the presence of five mouse-adapted mutation sites suggests that Omicron may have evolved in a mouse host.Mutations in the Omicron receptor-binding domain(RBD)region,in particular,have potential implications for the ongoing pandemic. | Yamin Sun Wenchao Lin Wei Dong Jianguo Xu | 2022 | Journal of Biosafety and Biosecurity2022，4，1： | 1 |
| 14 | Transmission fluctuation method for particle analysis in multiphase flow显示文摘 | SHEN Jianqi XU Yamin YU Bin | 2008 | International Journal of Multiphase Flow2008，34，10： | 1 |
| 15 | Deposition of Ag Nanoparticles on Carbon Microspheres Surface:Evaluation of Structures,Electrochemical and Optical Properties显示文摘A hybrid material of carbon microspheres(CMSs) with Ag decoration(Ag/CMSs) was developed.Poly(3-hexylthiophene):Ag/CMSs composite film was prepared by spin-coating.Scanning electron microscopy,transmission electron microscopy,Fourier transform infrared spectrometry,X-ray diffraction,thermogravimetric analysis and cyclic voltammetry were employed to analyze the morphologies,structures,thermal properties and energy levels of Ag/CMSs.The optical property of the composite films was characterized by ultraviolet-visible spectrophotometry and fluorescent spectrometry.The results indicate that silver nanoparticles(AgNPs,d = 10-20 nm) are distributed on the surface of CMSs.LUMO and HOMO energy levels of Ag/CMSs are-3.97 and-5.52 e V,below the vacuum energy level,respectively,indicating that it is feasible to use Ag/CMSs as an electron acceptor.Ag NPs are blended into the active layer to trigger localized surface plasmon resonance,and consequently enhance light harvesting.The coupling of surface plasmons and excitons increased the probability of exciton dissociation. | 杨维佳 HAO Yamin YAN Lingpeng 杨永珍 陈永康 LIU Xuguang XU Bingshe | 2016 | Journal of Wuhan University of Technology(Materials Science)2016，31，4： | 1 |
| 16 | An experimental stud-y of pressure loss and heat transfer in the pin fin-dimplechannels with various dimple depths 显示文摘 | RAO Yu WAN Chaoyi XU Yamin | 2012 | InternationalJournal of Heat and Mass Transfer2012，55，2324： | 1 |
| 17 | Time to Take Actions to Reduce the Harmful Use of Alcohol in China显示文摘Harmful use of alcohol negatively impacts and harms the drinkers,the people around them,and society at large.Harmful use of alcohol ranks among the top 5 risk factors for disease,disability,and death worldwide,and alcohol consumption is related to approximately 230 health conditions including infectious disease,noncommunicable diseases,and injuries(1–2). | Ning Ji Yamin Bai Jianwei Xu Min Liu Ainan Jia | 2021 | China CDC weekly2021，3，4： | 0 |
| 18 | OBLIVIOUS TRANSFER WITH ACCESS CONTROL AND IDENTITY-BASED ENCRYPTION WITH ANONYMOUS KEY ISSUING显示文摘In ACM'CCS 2009,Camenisch,et al.proposed the Oblivious Transfer with Access Control(AC-OT) in which each item is associated with an attribute set and can only be available,on request,to the users who have all the attributes in the associated set.Namely,AC-OT achieves access control policy for conjunction of attributes.Essentially,the functionality of AC-OT is equivalent to the sim-plified version that we call AC-OT-SV:for each item,one attribute is associated with it,and it is requested that only the users who possess the associated attribute can obtain the item by queries.On one hand,AC-OT-SV is a special case of AC-OT when there is just one associated attribute with each item.On the other hand,any AC-OT can be realized by an AC-OT-SV.In this paper,we first present a concrete AC-OT-SV protocol which is proved to be secure in the model defined by Camenisch,et al..Then from the protocol,interestingly,a concrete Identity-Based Encryption(IBE) with Anonymous Key Issuing(AKI) is given which is just a direct application to AC-OT-SV.By comparison,we show that the AKI protocol we present is more efficient in communications than that proposed by Chow. | Xu Lingling Zhang Fangguo Wen Yamin | 2011 | Journal of Electronics(China)2011，28，4： | 0 |
| 19 | Photoelectrochemical Biosensor for 5-Formylcytosine Based on WS_(2)/Bi/Bi_(2)O_(2)CO_(3) Nanocomposite and Rolling Circle Amplification显示文摘As a key epigenetic modification,5-formylcytosine(5fC)controls many important cell functions,such as gene expression and cell differentiation.However,5fC exists in mammalian tissues and cells with low content,and its structure is highly similar to 5-methylcytosine(5mC),5-hydroxymethylcytosine(5hmC)and 5-carboxycytosine(5caC), which requires the detection method for detecti ng 5fC with high sensitivity and specificity.In this experiment,WS_(2)/Bi/Bi_(2)O_(2)CO_(3) was used as the photoactive material,5fC antibody was used as the target molecule recog nition reage nt,and rolling amplification(RCA)was employed as the signal amplification strategy to con struct a no vel photoelectrochemical biose nsor for detecti ng 5-formylcytosi ne deox ynu cleotide(SfdCTP). | Qian Wang Huanshun Yin Yunlei Zhou Lulu Cao Zhengkun Yu Yamin Xu Shiyun Ai | 2022 | Chinese Journal of Chemistry2022，40，2： | 0 |
| 20 | Massive‐scale genomic analysis reveals SARS‐CoV‐2 mutation characteristics and evolutionary trends显示文摘The severe acute respiratory syndrome coronavirus 2(SARS‐CoV‐2)pandemic resulted in significant societal costs.Hence,an in‐depth understanding of SARS‐CoV‐2 virus mutation and its evolution will help determine the direction of the COVID‐19 pandemic.In this study,we identified 296,728 de novo mutations in more than 2,800,000 high‐quality SARS‐CoV‐2 genomes.All possible factors affecting the mutation frequency of SARS‐CoV‐2 in human hosts were analyzed,including zinc finger antiviral proteins,sequence context,amino acid change,and translation efficiency.As a result,we proposed that when adenine(A)and tyrosine(T)bases are in the context of AM(M stands for adenine or cytosine)or TA motif,A or T base has lower mutation frequency.Furthermore,we hypothesized that translation efficiency can affect the mutation frequency of the third position of the codon by the selection,which explains why SARS‐CoV‐2 prefers AT3 codons usage.In addition,we found a host‐specific asymmetric dinucleotide mutation frequency in the SARS‐CoV‐2 genome,which provides a new basis for determining the origin of the SARS‐CoV‐2.Finally,we summarize all possible factors affecting mutation frequency and provide insights into the mutation characteristics and evolutionary trends of SARS‐CoV‐2. | Yamin Sun Min Wang Wenchao Lin Wei Dong Jianguo Xu | 2022 | mLife2022，1，3： | 0 |
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