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| 1 | Non-canonical regulation of SPL transcription factors by a human OTUBl-like deubiquitinase defines a new plant type rice associated with higher grain yield显示文摘完成增加的谷物生产率长是引起节目的谷物的制服的焦点。ideotype 途径被用来在国际瑞斯研究院并且在中国改进米饭收益潜力。然而,在米饭的收益相关的特点的基因基础仍然保持不清楚。这里,我们显示出那一个主要量的特点地点, qNPT1,通过建筑学由更少 tillers 描绘了的一种新植物类型(NPT ) 的决心的行为,更坚定的灰煤杆和更大的圆锥花序,并且它与相同编码 deubiquitinating 酶到人的 OTUB1。OsOTUB1 的 Downregulation 提高 meristematic 活动,导致在谷物产量的减少的 tiller 数字,增加的谷物数字,提高的谷物重量和米饭的作为结果的增加。不同于人的 OTUB1, OsOTUB1 能劈开连接 K48 、连接 K63 的 polyubiquitin。OsOTUB1 与 E2 结合 ubiquitin 蛋白质 OsUBC13 和 squamosa 倡导者绑定交往像蛋白质的抄写因素 OsSPL14。OsOTUB1 和 OsSPL14 分享普通目标基因,和他们的物理相互作用限制 OsSPL14 的连接 K63 的 ubiquitination (K63Ub ) ,它接着支持 OsSPL14 的 K48Ub 依赖的 proteasomal 降级。相反地, OsOTUB1 的 loss-of-function 与 OsSPL14 的高水平的累积被相关,导致 NPT 建筑学。我们也证明 high-yielding npt1 和 dep1-1 等位基因节节上升为增加在当前是可完成的的上面的米饭收益潜力提供新策略。 | Shuansuo Wang Kun Wu Qian Qian Qian Liu Qi Li Yajun Pan Yafeng Ye Xueying Liu Jing Wang Jianqing Zhang Shan Li Yuejin Wu Xiangdong Fu | 2017 | Cell Research2017，27，9： | 33 |
| 2 | PandaX: a liquid xenon dark matter experiment at CJPL显示文摘PandaX is a large liquid-xenon detector experiment usable for direct dark-matter detection and 136Xe double-beta decay search.The central vessel was designed to accommodate a staged target volume increase from initially 120 kg(stage I)to 0.5 t(stage II)and eventually to a multi-ton scale.The experiment is located in the Jinping Deep-Underground Laboratory in Sichuan,China.The detector operates in dual-phase mode,allowing detection of both prompt scintillation,and ionization charge through proportional scintillation.In this paper a detailed description of the stage I detector design and performance as well as results established during the commissioning phase are presented. | CAO XiGuang CHEN Xun CHEN YunHua CUI XiangYi FANG DeQing FU ChangBo GIBONI Karl L. GONG HaoWei GUO GuoDong HE Ming HU Jie HUANG XingTao JI XiangDong JU YongLin LI ShaoLi LIN Qing LIU HuaXuan LIU JiangLai LIU Xiang LORENZON Wolfgang MA YuGang MAO YaJun NI KaiXuan PUSHKIN Kirill REN XiangXiang SCHUBNELL Michael SHEN ManBing SHI YuJie STEPHENSON Scott TAN AnDi TARLé Greg WANG HongWei WANG JiMing WANG Meng WANG XuMing WANG Zhou WEI YueHuan WU ShiYong XIAO MengJiao XIAO Xiang XIE PengWei YE Tao YOU YingHui ZEN XiongHui ZHANG Hua ZHANG Tao ZHAO HaiYing ZHAO Li ZHOU XiaoPeng ZHU ZhongHua | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，8： | 9 |
| 3 | Sensitivity and regionally proximal relation in minimal systems显示文摘A topological dynamical system is n-sensitive,if there is a positive constant such that in each non-empty open subset there are n distinct points whose iterates will be apart from the constant at least for a same moment.The properties of n-sensitivity in minimal systems are investigated.It turns out that a minimal system is n-sensitive if and only if the n-th regionally proximal relation Q_n contains a point whose coordinates are pairwise distinct.Moreover,the structure of a minimal system which is n-sensitive but not(n+1)-sensitive(n≥2)is determined. | SHAO Song YE XiangDong ZHANG RuiFeng | 2008 | Science China Mathematics2008，51，6： | 5 |
| 4 | Microstructure and properties of novel Al-Ce-Sc,Al-Ce-Y,Al-Ce-Zr and Al-Ce-Sc-Y alloy conductors processed by die casting,hot extrusion and cold drawing显示文摘In order to overcome the trade-off between the strength and electrical conductivity of aluminum alloy conductors,the new Al-Ce-Sc,Al-Ce-Y,Al-Ce-Zr and Al-Ce-Sc-Y alloys were prepared by die casting,high temperature homogenization treatment,hot extrusion and cold drawing.Adding Sc and Y eliminated the dendrite segregation of the as-cast Al-0.2 Ce alloy and promoted the formation of equiaxed grains with the average grain size of 142.5μm.The Al-0.2 Ce-0.2 Sc-0.1 Y alloy inherited the great tensile properties of Al-0.2 Ce-0.2 Sc alloy and the high electrical conductivity of Al-0.2 Ce-0.1 Y alloy simultaneously.After cold drawing and annealing at 200℃for 5 h,the ultimate tensile strength of Al-0.2 Ce-0.2 Sc-0.1 Y alloy reached 200 MPa and 198 MPa,the elongation reached 6.8%and 8.5%,and the electrical conductivity reached 61.01%and 61.77%,respectively.The main second phase of Al-0.2 Ce-0.2 Sc-0.1 Y alloy after hot extrusion were Al_(13)Fe_3 Ce containing a few Y and Si atoms.The larger size and proportion of the second phase greatly reduced the concentration of solute Fe and Si atoms and the addition of Y significantly decreased the density of defects after cold drawing compared to Al-0.2 Ce-0.2 Sc alloy,which improved electrical conductivity of the alloy.Furthermore,the dispersed and coherent nano-size Al_3 Sc precipitions of Al-0.2 Ce-0.2 Sc-0.1 Y alloy greatly improved strength,elongation and heat resistance.Compared with Al-0.2 Ce-0.2 Sc alloy,the lower density of dislocation,stacking fault and subgrain boundary and the larger size of Al_3 Sc precipitions with enrichment of Y atoms enable the Al-0.2 Ce-0.2 Sc-0.1 Y alloy to maintain high strength,elongation and electrical conductivity after annealing. | Weiyi Wang Qinglin Pan Geng Lin Xiaoping Wang Yuqiao Sun Xiangdong Wang Ji Ye Yuanwei Sun Yi Yu Fuqing Jiang Jun Li Yaru Liu | 2020 | Journal of Materials Science & Technology2020，58，23： | 4 |
| 5 | The rational design of multiple molecular module-based assemblies for simultaneously improving rice yield and grain quality显示文摘Rice is one of the most important staple food for over half of the world's population,and a substantial increase in productivity and quality of rice grain will be required to feed a growing human population.Grain size and shape are the two important components contributing to grain yield and quality,because they impact both yield potential and end-use quality.Over the past 50 years。 | Kun Wu Xiaopeng Xu Nan Zhong Haixiang Huang Jianping Yu Yafeng Ye Yuejin Wu Xiangdong Fu | 2018 | Journal of Genetics and Genomics2018，45，6： | 4 |
| 6 | Wheat breeding history reveals synergistic selection of pleiotropic genomic sites for plant architecture and grain yield显示文摘Diversity surveys of crop germplasm are important for gaining insights into the genomic basis for plant architecture and grain yield improvement,which is still poorly understood in wheat.In this study,we exome sequenced 287 wheat accessions that were collected in the past 100 years.Population genetics analysis identified that 6.7%of the wheat genome falls within the selective sweeps between landraces and cultivars,which harbors the genes known for yield improvement.These regions were asymmetrically distributed on the A and B subgenomes with regulatory genes being favorably selected.Genome-wide association study(GWAS)identified genomic loci associated with traits for yield potential,and two underlying genes,TaARF12 encoding an auxin response factor and TaDEP1 encoding the G-proteinγ-subunit,were located and characterized to pleiotropically regulate both plant height and grain weight.Elite single-nucleotide haplotypes with increased allele frequency in cultivars relative to the landraces were identified and found to have accumulated over the course of breeding.Interestingly,we found that TaARF12 and TaDEP1 function in epistasis with the classical plant height Rht-1 locus,leading to propose a“Green Revolution”-based working model for historical wheat breeding.Collectively,our study identifies selection signatures that fine-tune the gibberellin pathway during modern wheat breeding and provides a wealth of genomic diversity resources for the wheat research community. | Aili Li Chenyang Hao Zhenyu Wang Shuaifeng Geng Meiling Jia Fang Wang Xiang Han Xingchen Kong Lingjie Yin Shu Tao Zhongyin Deng Ruyi Liao Guoliang Sun Ke Wang Xingguo Ye Chengzhi Jiao Hongfeng Lu Yun Zhou Dengcai Liu Xiangdong Fu Xueyong Zhang Long Mao | 2022 | Molecular Plant2022，15，3： | 4 |
| 7 | Strong interface contact between NaYF_(4):Yb,Er and CdS promoting photocatalytic hydrogen evolution of NaYF_(4):Yb,Er/CdS composites显示文摘To acquire efficient photocatalysts,it is necessary to make effective use of visible light/Near Infrared(NIR)light,which takes up a large percentage of sunlight.Integrating upconversion materials with visible light active photocatalysts has attracted much attention in this regard.The interface contact between upcon-version material and photocatalyst has potential influence on the properties and thus the performance of the system.In this work,NaYF_(4):Yb,Er/CdS composites of the upconversion material NaYF_(4):Yb,Er nanorods and CdS nanoparticles were synthesized by ion adsorption/precipitation process and were then annealed in an argon atmosphere at different temperatures to modulate the microstructures.The annealing pro-cess endows the crystal transformation of cubic CdS with low crystallinity to hexagonal CdS with high crystallinity and,importantly,good interface contact between NaYF_(4):Yb,Er and CdS.Consequently,the hy-drogen evolution activity greatly increases from 171 to 2539μmol h^(−1) g^(−1) under the light irradiation ofλ>400 nm,and from 0 to 19μmol h^(−1) g^(−1) under the light irradiation ofλ>600 nm.This work might provide a useful reference for the rational design of promising photocatalyst involving upconversion ma-terials. | Huaze Zhu Yongqiang Yang Yuyang Kang Ping Niu Xiangdong Kang Zhiqing Yang Hengqiang Ye Gang Liu | 2022 | Journal of Materials Science & Technology2022，，7： | 3 |
| 8 | A facile method to fabricate surfaces showing superhydrophilicity in air and superhydrophobicity in oil显示文摘The changes of the wettability of the solid surfaces have attracted massive attention due to their important practical implications in numerous fields. As a new subject, the research on the wettability under the different environments is still in its early stage. So the fundamental research must be performed for the practical applications under different environments. However, it is seldom that the comprehensive wettability of a surface in air, in water and in oil has been reported. In this paper, the authors investigated the wettability of the stainless steel mesh coated with polyurethane in the above three different environments. The surface of the uncoated mesh was found to be hydrophobic in air, but the surface of the coated mesh was superhydrophilic in air. More interestingly, the surfaces of the coated meshes were superoleophilic in water and superhydrophobic in oil. Due to the coated meshes with these wettabilities were fabricated via a facile two-step method, the presented method may be adopted for large-scale industrial production, in various fields, such as icing prevention or the oil-field industry. | YE XiangDong GUO YuXuan JIA YanChao YE Xin WANG Shuai CAI AnJiang WU XiaoJun SHAO JinYou | 2017 | Science China(Technological Sciences)2017，60，11： | 2 |
| 9 | A local variational relation and applications显示文摘 | Wen Huang Xiangdong Ye | 2006 | Israel Journal of Mathematics2006，，1： | 1 |
| 10 | A local variational relation and applications显示文摘 | Wen Huang Xiangdong Ye | 2006 | Israel Journal of Mathematics2006，，1： | 1 |
| 11 | Analysis on virus resistance and fruit quality for T4 generation of transgenic papaya显示文摘Molecular biological characterization,fruit char-acters,and nutrients were analyzed for T4 generation of transgenic papaya.All transgenic papaya plants with the mutated replicase(RP)gene from papaya ringspot virus(PRSV)showed high resistance or immunity against PRSV in the field.The RP transgene can be steadily inherited to,and expressed at RNA level,the progenies.The growth char-acteristics of transgenic papaya were much better than non-transgenic papaya in the field.The non-transgenic papaya seedlings began to show typical symptoms caused by PRSV after being inoculated with PRSV.They died quickly and never grew to produce fruit.The adult trees developed yellow leaves and produced smaller fruits and were doomed to a slow death after some time,while most of transgenic papaya plants(about 91.8%)did not show any symptoms caused by PRSV,and produced more,bigger,and high quality fruits.Compared with non-transgenic plants,the fresh fruit length of T4 gen-eration of transgenic papaya increased 2.6%-5%,and the diameter decreased 0.6%-1.5%.The flesh thickness of fresh fruit increased 12%-15%,which made it fitter for eating.Although the fresh fruit quality changed,there was no sig-nificant difference between transgenic and non-transgenic papaya.The quality characteristics of dry fruit including the contents of water,lipid,N,protein,reduced sugar,vitamin A,vitamin C,and carotene in the T4 generation of transgenic papaya were all the same as their non-transgenic parents.This means that transgenic plants and non-transgenic plants are substantially equivalent,and the transgene has no effect on dry fruit quality.In this study,we found that vitamin A and vitamin C in red-fleshed papaya were 1.4-1.8 and 1.78-2.07 times more than the yellow-fleshed ones,respectively,while N and protein were only 84.2%-92.1%and 82.1%-98.9%of the yellow-fleshed ones. | WEI Xiangdong LAN Congyu LU Zhijing YE Changming | 2007 | Frontiers in Biology2007，2，3： | 1 |
| 12 | Multi-recurrence and van der Waerden systems显示文摘We explore recurrence properties arising from dynamical approach to the van der Waerden theorem and similar combinatorial problems. We describe relations between these properties and study their consequences for dynamics. In particular, we present a measure-theoretical analog of a result of Glasner on multi-transitivity of topologically weakly mixing minimal maps. We also obtain a dynamical proof of the existence of a C-set with zero Banach density. | KWIETNIAK Dominik LI Jian OPROCHA Piotr YE XiangDong | 2017 | Science China Mathematics2017，60，1： | 1 |
| 13 | Investigation of a Cluster of 2019 Novel Coronavirus Disease (COVID-19) with Possible Transmission During the Incubation Period--Shenyang City, China, 2020显示文摘In December of 2019,a novel coronavirus(2019-nCoV)emerged in Wuhan China,which was later named COVID-19(1).It quickly spread and as of February 11,2020,there were 38,800 laboratoryconfirmed cases,16,067 suspected cases,and 1,113 attributable deaths that have affected all provinciallevel administrative divisions(PLADs)of China's Mainland(2).The first confirmed COVID-19 case in Shenyang City,the capital of Liaoning Province,occurred on January 22,2020,with a total of 9 confirmed cases by January 29,2020.Of these cases,4 were clustered in one family.Shenyang CDC immediately launched an investigation to determine routes of transmission,scale of the outbreak,and evidence for epidemic control. | Ping Wang Zhiyong Lian Ye Chen Ying Qi Huijie Chen Xiangdong An | 2020 | China CDC weekly2020，2，8： | 1 |
| 14 | Non-wandering points and the depth of a gragh map显示文摘 | | 2000 | J Austral Math Soc2000，69，： | 1 |
| 15 | The center and the depth of the center of a tree map显示文摘 | | 1993 | Bull Austral Math Soc1993，48，： | 1 |
| 16 | Mapping of de novo mutations in primary biliary cholangitis to a disease-specific co-expression network underlying homeostasis and metabolism显示文摘Primary biliary cholangitis(PBC) is an autoimmune disease involving dysregulation of a broad array of homeostatic and metabolic processes. Although considerable single-nucleotide polymorphisms have been unveiled, a large fraction of risk factors remains enigmatic. Candidate genes with rare mutations that tend to confer more deleterious effects need to be identified. To help pinpoint cellular and developmental mechanisms beyond common noncoding variants, we integrate whole exome sequencing with integrative network analysis to investigate genes harboring de novo mutations. Prominent convergence has been revealed on a network of disease-specific co-expression comprised of 55 genes associated with homeostasis and metabolism. The transcription factor gene MEF2 D and the DNA repair gene PARP2 are highlighted as hub genes and identified to be up-and down-regulated, respectively, in peripheral blood data set. Enrichment analysis demonstrates that altered expression of MEF2 D and PARP2 may trigger a series of molecular and cellular processes with pivotal roles in PBC pathophysiology. Our study identifies genes with de novo mutations in PBC and suggests that a subset of genes in homeostasis and metabolism tend to act in synergy through converging on co-expression network, providing novel insights into the etiology of PBC and expanding the pool of molecular candidates for discovering clinically actionable biomarkers. | Lu Wang Jinchen Li Chan Wang Ruqi Tang Jialong Liang Yuhua Gong Yaping Dai Ningling Ding Jian Wu Na Dai Lei Liu Yi Zhao Youlin Shao Weifeng Zhao Peng Jiang Xingjuan Shi Weichang Chen Ye Tian Xiangdong Liu Xiong Ma Zhongsheng Sun | 2022 | Journal of Genetics and Genomics2022，49，2： | 1 |
| 17 | RP5-1148A21.3 (lncRP5) exerts oncogenic function in human ovarian carcinoma显示文摘Ovarian cancer(OC)is a fatal gynecological malignancy that is difficult to diagnose at early stages.Various long non-coding RNAs(lncRNAs)are aberrantly expressed in OC and exert regulatory effects on OC;however,the underlying mechanism requires in-depth investigation.This work is designed to explore the molecular regulatory axis of a newly identified lncRNA in OC,that is,lncRNA RP5-1148A21.3(lncRP5).RT-qPCR shows lncRP5 is significantly upregulated in OC patients and cell lines,and it is mainly located in the cytoplasm of OC cells.The results of CCK-8,colony formation,and transwell assays demonstrate that overexpression of lncRP5 greatly contributes to malignant behaviors of OC cells,while inhibition of lncRP5 shows the opposite effects.Moreover,the binding relationship between lncRP5 and miR-545-5p is predicted by bioinformatics and is further verified by luciferase assay.Functionally,the regulatory effects of lncRP5 and miR-545-3p are negatively related;miR-545-5p serves as a tumor suppressor in OC.Further studies demonstrate that PTP4A1 is the target gene of miR-545-5p.Overexpression of PTP4A1 abrogates the inhibitory function of miR-545-5p on OC cell growth and metastasis.The lncRP5/miR-545-5p/PTP4A1 axis is subsequently demonstrated in vivo,and knockdown of lncRP5 notably inhibits tumor growth.This study provides a novel regulatory mechanism of OC,which may contribute to the diagnosis and therapy of OC. | Pingping Sun Aimei Bao Xiangdong Hua Jian Cao Ye Ding | 2022 | Acta Biochimica et Biophysica Sinica2022，54，2： | 1 |
| 18 | Epidemiological analysis of syphilis in China from 1995 to 2000显示文摘 | Zhang Guocheng Ye Shunzhang | 2001 | Chin J Sex Transm Infect2001，1，： | 1 |
| 19 | Synthesis and characterization of ( h0l ) oriented high-silica zeolite beta membrane显示文摘 | Yanli Chen Guangshan Zhu Ye Peng Xiangdong Yao Shilun Qiu | 2009 | Microporous and Mesoporous Materials2009，，1： | 1 |
| 20 | A Note on Double Minimality显示文摘It is known that a minimal prime system is either a subshift or with a connected phase space(Keynes and Newton TransAmMath Soc 217:237-255,1976).We show that a double minimal system is a subshift;this implies immediately that no non-periodic map has 4-fold topological minimal self-joinings.We also prove that a POD system is either uniformly rigid or is a subshift. | Wen Huang Xiangdong Ye | 2015 | Communications in Mathematics and Statistics2015，3，1： | 1 |
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