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92篇 您的检索式:作者名="Yang Haiying"
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1Mapping wetland changes in China between 1978 and 2008显示文摘Four wetland maps for all China have been produced,based on Landsat and CBERS-02B remote sensing data between 1978 and 2008 (1978,1990,2000 and 2008).These maps were mainly developed by manual interpretation and validated by substantial field investigation in 2009.Based on these maps,we analyzed the 2008 wetland distribution in China and discussed wetland changes and their drivers over the past 30 years.(i) There were about 324097 km 2 of wetlands in 2008,for which inland marshes or swamps were the most common wetland type (35%),with lakes (26%) second.Most of the wetlands were in Heilongjiang,Inner Mongolia,Qinghai and Tibet,occupying about 55% of the national wetland area.(ii) From 1978 to 2008,China's wetland area continually and significantly decreased,by about 33% based on changes in the wetland map.This was in sharp contrast to the increase in artificial wetlands,which increased by about 122%.Inland marshes accounted for the main loss of total wetlands from 1978 to 2000.From 2000 through 2008,riverine and lacustrine wetlands constituted the main wetland loss.Fortunately however,the rate of wetland loss decreased from 5523 to 831 km 2 /a.(iii) The change ratio of lost natural wetlands (including inland and coastal wetlands) to non-wetlands has decreased slightly over the past 30 years.From 1978 to 1990,nearly all natural wetlands (98%) lost were transformed into non-wetlands.However,the ratio declined to 86% from 1990 to 2000,and to 77% from 2000 to 2008.(iv) All Chinese provinces were divided into three groups according to patterns of wetland changes,which could relate to the driving forces of such changes.Tibet was completely different from other provinces,as it was one representative example in which there was a net wetland increase,because of global warming and decreased human activity since 1990.Increased economic development caused considerable wetland loss in most eastern provinces,and artificial wetlands increased.NIU ZhenGuo ZHANG HaiYing WANG XianWei YAO WenBo ZHOU DeMin ZHAO KuiYi ZHAO Hui LI NaNa HUANG HuaBing LI CongCong YANG Jun LIU CaiXia LIU Shuang WANG Lin LI Zhan YANG ZhenZhong QIAO Fei ZHENG YaoMin CHEN YanLei SHENG YongWei GAO XiaoHong ZHU WeiHong WANG WenQing WANG Hong WENG YongLing ZHUANG DaFang LIU JiYuan LUO ZhiCai CHENG Xiao GUO ZiQi GONG Peng 2012Chinese Science Bulletin2012,57,22:51
2The first all-season sample set for mapping global land cover with Landsat-8 data显示文摘We report the world's first all-season training and validation sample sets for global land cover classification with Landsat-8 data.Prior to this,such samples were only available at a single date primarily from the growing season.It is unknown how much limitation such a single-date sample has to mapping global land cover in other seasons of the year.To answer this question,we selected available Landsat-8 images from four seasons and collected training and validation samples from them.We compared the performances of training samples in different seasons using Random Forest algorithm.We found that the use of training samples from any individual season would result in the best overall classification accuracy when validated by samples in the same season.The global overall accuracy from combined best seasonal results was 67.2% when classifying the 11 Level-1 classes in the Finer Resolution Observation and Monitoring of Global Land Cover(FROM-GLC) classification system.The use of training samples from all seasons(named all-season training sample set hereafter) produced an overall accuracy of 67.0%.We also tested classification within 10° latitude 60° longitude zones using all-season training subsample within each zone and obtained an overall accuracy of 70.2%.This indicates that properly grouped subsamples in space can help improve classification accuracies.All the results in this study seem to suggest that it is possible to use an all-season training sample set to reach global optimality with universal applicability in classifying images acquired at any time of a year for global land cover mapping.Congcong Li Peng Gong Jie Wang Zhiliang Zhu Gregory S. Biging Cui Yuan Tengyun Hu Haiying Zhang Qi Wang Xuecao Li Xiaoxuan Liu Yidi Xu Jing Guo Caixia Liu Kwame O. Hackman Meinan Zhang Yuqi Cheng Le Yu Jun Yang Huabing Huang Nicholas Clinton 2017Science Bulletin2017,62,7:21
3Influence of Water Stress on Endogenous Hormone Contents and Cell Damage of Maize Seedlings显示文摘Phytohormones play critical roles in regulating plant responses to stress. We investigated the effects of water stress induced by adding 12% (w/v) polyethylene glycol to the root medium on the levels of abscisic acid (ABA), indole-3-acid (IAA), zeatin (ZT), and gibberellin3 (GA3) in maize leaves. The results suggested that water stress had significant effects on the four hormone levels. There was a transient increase in the IAA content during the initial stage of adaptation to water stress in maize leaves, but it dropped sharply thereafter in response to water stress. ABA content increased dramatically in maize leaves after 24 h of exposure to water stress, and then the high levels of ABA were maintained to the end. The contents of ZT and GA3 rapidly declined in maize leaves subjected to water stress. The effects of water stress on chlorophyll content, electrolyte leakage and malondialdehyde levels in maize leaves were also studied. The variation of cell damage was negatively correlated with ZT and GA3 levels in maize leaves under water stress. Thus, we explored the roles of ZT and GA3 on the growth of maize seedlings under water stress by exogenous application. It is possible that both ZT and GA3 were effective in protecting maize seedlings from water stress, which would be of great importance for the improvement of drought tolerance in maize by genetic manipulation.Chunrong Wang Aifang Yang Haiying Yin Juren Zhang 2008Journal of Integrative Plant Biology2008,50,4:17
4Functional regionalization with the restriction of ecological shelter zones: A case of Zhaotong in Yunnan显示文摘生态的躲蔽处地区重建是瞄准到国家,区域和盆的生态的安全的生态系统恢复和保存工程。长江的上面的活动范围的生态的躲蔽处地区的重建成为了西方的发展策略的最重要的任务之一。这篇文章,作为一个例子拿 Zhaotong,学习生态的躲蔽处地区的功能的区域化。学习为其主要任务是环境保留的小、中等的区域的功能的区域化供应一个盒子。与功能的区域化的理论的指导,并且基于 Zhaotong 鈥檚 天赋的分析,生态、社会经济的因素,纸为因素建议五个原则选择。这些原则包括:(1 ) 颠倒顺序评估;(2 ) 选择主要因素;(3 ) 保留镇的行政区域的完全;并且(4 ) 由本地管理使产品可接受。为了分析选择因素,在 2002 的 LUCC 数据, 1:50,000 消除地图和镇单位的空间地位,在 2004 的社会经济的统计数据被使用。RS 和 GIS 工具也被使用融化传统、现代的地理方法。这将对在多山的区域的功能的区域化研究有用。作为一个结论,生态的保存或经济开发的领先的功能的区域分别地被建议。Zhaotong 城市被划分成二水平的功能的区域。第一水平包括三条带功能的区域和他们将带分区的发展中的方向。秒级包括八个分区,它是实现的政策区域,和愿望供应指导到 Zhaotong 鈥檚 生态的躲蔽处地区重建。DU Yu WANG Chuansheng ZHAO Haiying YANG Xiaoguang 2007Journal of Geographical Sciences2007,17,3:5
5Sensitive electrochemical DNA sensor for the detection of HIV based on a polyaniline/graphene nanocomposite显示文摘A nanocomposite of polyaniline/graphene(PAN/GN)was prepared using reverse-phase polymerization.The nanocomposite material was dropcast onto a glassy carbon electrode(GCE).Then,a single-stranded DNA(ssDNA)probe for HIV-1 gene detection was immobilized on the modified electrode,and the negative charged phosphate backbone of the HIV-1 was bound to the modified electrode surface via p-p*stacking interactions.The hybridization between the ssDNA probe and the target HIV-1 formed doublestranded DNA(dsDNA),and the electron transfer resistance of the electrode was measured using impedimetric studies with a[Fe(CN)6]^(3-/4-)redox couple.Under the optimized experimental conditions,the change of the impedance value was linearly related to the logarithm of the concentration of HIV genes in the range from 5.0×10^(-16)M to 1.0×10^(-10)M(R=0.9930),and the HIV sensor exhibited a lower detection limit of 1.0×10^(-16)M(S/N=3).The results show that this biosensor presented wonderful selectivity,sensitivity and specificity for HIV-1 gene detection.Thus,this biosensor provides a new method for the detection of HIV gene fragments.Qiaojuan Gong Haixia Han Haiying Yang Meiling Zhang Xiaoling Sun Yunxia Liang Zhaorong Liu Wenchan Zhang Jinli Qiao 2019Journal of Materiomics2019,5,2:5
6In Vivo Corrosion Resistance of Ca-P Coating on AZ60 Magnesium Alloy显示文摘Xing Xiao Haiying Yu Qingsan Zhu Guangyu Li Yang Qu Rui Gu 2013Journal of Bionic Engineering2013,10,2:5
7A β-glucosidase-producing M-2 strain: Isolation from cow dung and fermentation parameter optimization for flaxseed cake显示文摘Flaxseed cake contains cyanogenic glucosides, which can be metabolized into hydrocyanic acid in an animal's body, leading to asphyxia poisoning in cells. Beta-glucosidase is highly efficient in degrading cyanogenic glucosides. The Cattle may have b-glucosidase-producing strains in the intestinal tract after eating small amounts of flaxseed cake for a long time. This study aimed to isolate of a strain from cow dung that produces b-glucosidase with high activity and can significantly reduce the amount of cyanogenic glucosides. We used cow dung as the microflora source and an esculin agar as the selective medium. After screening with 0.05% esculin and 0.01% ferric citrate, we isolated 5 strains producing high amounts of b-glucosidase. In vitro flaxseed cake fermentation was fermented by these 5 strains, in which the strain M-2 exerted the best effect(P < 0.05). The strain M-2 was identified as Lichtheimia ramosa and used as the fermentation strain to optimize the fermentation parameters by a single factor analysis and orthogonal experimental design. The optimum condition was as follows: inoculum size3%, water content 60%, time 144 h, and temperature 32℃. Under this condition, the removal rate of cyanogenic glucosides reached 89%, and crude protein increment reached 44%. These results provided a theoretical basis for the removal of cyanogenic glucosides in flaxseed and the comprehensive utilization of flaxseed cake.Chenhui Li Junshu Wei Yaping Jing Baoxia Teng Pingrong Yang Xinjun Chen Haiying Huang Tang Zhao Tuanjie Che Chunjiang Zhang 2019Animal Nutrition2019,,1:5
8Phosphorite generative processes around the Precambrian-Cambrian boundary in South China: An integrated study of Mo and phosphate O isotopic compositions显示文摘Large phosphorite deposits in Central Guizhou,China,were formed around the Precambrian/Cambrian boundary(PC/C),including the Ediacaran(Doushantuo stage)and early Cambrian(Gezhongwu stage).Among them,Gezhongwu phosphorite from Zhijin are enriched in rare earth elements(REE)plus yttrium(REY),reaching 3.503 million tons.Although phosphorites have attracted great attention,the specific sources P and REY remained unclear.To determine the P and REY sources and establish a phosphogenic model of PC/C phosphorite,we present an integrated dataset of Mo and phosphate O isotopes for the first time,along with carbonate C and O isotopes,geology,petrology,and geochemistry.In all samples,d18Op,Y/Ho,and Zr/Hf decreased from the Ediacaran to the early Cambrian,indicating increased terrigenous weathering fluxes while decreased upwelling water input.Furthermore,terrigenous weathering delivery significantly elevated marine REY concentrations in the Cambrian in Zhijin.The Ceanom and d98/95Mo suggest that seawater was oxidized in the later Ediacaran and became entirely oxic in the early Cambrian.The positive feedback between oxygen levels in atmosphere and primary productivity caused progressive oxygenation in ocean-atmosphere system and enable phosphorites to be formed by different mechanisms.Results show that the Lower Doushantuo consist of abiotic intraclasts and exhibited“seawaterlike”REY types,indicating abiological and mechanical reworking phosphogenesis.The Upper Doushantuo and Gezhongwu Formation contained mainly microbial debris and abiogenic intraclasts,and exhibit “hat-shaped”REY plots,suggesting microbially mediated phosphogenesis.Based on this data set,we developed a phosphogenic model illustrating formation of these two phosphorite deposits,wherein the Lower Doushantuo phosphorite formed through the reworking of pre-existing phosphatic sediments in anoxic and abiotic ocean,whereas the Upper Doushantuo and Gezhongwu phosphorite formed via microbial metabolisms in oxic and biotic conditions.Our study has implications on the PC/C phosphorite generative processes,as well as paleoenvironmental conditions.Haiying Yang Jiafei Xiao Yong Xia Zhuojun Xie Qinping Tan Jianbin Xu Shan He Shengwei Wu Xiqiang Liu Xingxiang Gong 2021Geoscience Frontiers2021,12,5:5
9Engineering optimization approach of nonaqueous electrolyte for sodium ion battery with long cycle life and safety显示文摘Electrolyte design strategies are closely related to the capacities, cycle life and safety of sodium–ion batteries. In this study, we aimed to optimize electrolyte with the focus on engineering aspects. The basic physicochemical properties including ionic conductivity, viscosity,wettability and thermochemical stability of the electrolytes using Na PF6 as the solute and the mixed solvent with different components of EMC,DMC or DEC in PC or EC were systematically measured. Ah pouch cell with NaNi_(1/3)Fe_(1/3)Mn_(1/3)O_(2)/hard carbon electrodes was used to evaluate the performance of the prepared electrolytes. By using the Inductive Coupled Plasma Emission Spectrometer(ICP), X-ray photoelectron spectroscopy(XPS), Thermogravimetric-differential scanning calorimetry(TG-DSC) and Accelerating Rate Calorimeter(ARC), we show that an optimized electrolyte can effectively promote the formation of a protective interfacial layer on two electrodes, which not only retards parasitic reactions between the electrodes and electrolyte but also suppresses dissolution of metal ions from the cathode. With an optimized electrolyte, a NaNi_(1/3)Fe_(1/3)Mn_(1/3)O_(2)/hard carbon cell can attain 56.16% capacity retention under the low temperature of -40℃, and can be able to retain 80%capacity retention after more than 2500 cycles while presenting excellent thermal safety.Haiying Che Xinrong Yang Yan Yu Chaoliang Pan Hong Wang Yonghong Deng Linsen Li Zi-Feng Ma 2021Green Energy & Environment2021,6,2:4
10A biomass carbon material with microtubule bundling and natural O-doping derived from goldenberry calyx and its electrochemical performance in supercapacitor显示文摘A promising biomass carbon material,manufactured by the carbonation of Physalis peruviana L.calyx at 700℃,is presented in this wo rk.Morphology characterization shows that the carbon material possesses long microtubule bundling and above 30%natural O-atom component on the surface.After KOH chemical etching,the materials maintain the oxygen content but exhibit more micropores and higher specific surface area up to 1732.6 m^2/g.Using as an electrode material for supercapacitor,the active carbon material exhibits high specific capacitance up to 339.7 F/g at 0.5 A/g in 3 mol/L KOH aqueous solution through three-electrode system.The active carbon material also exhibits excellent cycling stability(97%retention)by 10,000 cycles at 10 A/g.The outstanding electrochemical performances are attributing to the unique long microtubule bundling with much more pores and the abundant Oelement on the surface.This biomass carbon material with excellent electrochemical properties could be a useful material for multiple applications.Yang Liu Mengyi Zhang Liqiu Wang Yajuan Hou Chenxiao Guo Haiying Xin Shuang Xu 2020Chinese Chemical Letters2020,31,3:4
11Hydrothermal Synthesis and Properties of Y-zeolite-containing Composite Material with Micro/mesoporous Structure显示文摘有 micro/mesoporous 结构的 Y-zeolite-containing 合成材料从白陶土被综合了借助于在原处结晶化方法。获得的样品被 XRD 调查并且赌了方法。商业 Y 沸石和新奇 Y-zeolite-containing 的催化活动的评估合成材料在脉搏被执行有不同分子的尺寸的二个探查分子的微层析的站台:VGO 化工物品和 1,3,5 tri-isopropyl 苯。Y-zeolite-containing 合成材料富于外部表面和 meso-/macro-pores,这被发现;Y-zeolite-containing 合成材料与商业 Y 沸石相比表明了释放的更小的率。Zhou Jihong Min Enze Shu Xingtian Zong Baoning Yang Haiying Luo Yibin (State Key Laboratory of Catalytic Material and Reaction Engineering,Research Institute of Petroleum Processing,SINOPEC,Beijing 100083) 2010China Petroleum Processing & Petrochemical Technology2010,12,1:3
12Destabilization of linker histone H1.2 is essential for ATM activation and DNA damage repair显示文摘连接器 histone H1 在 DNA 损坏反应是更高的顺序染色质结构,而是它的参与的一个主人管理者,修理是不清楚的。这里,我们报导连接器 histone H1.2 是混乱毛细管扩张的一个必要管理者变异(ATM ) 激活。我们证明 H1.2 通过和 ATM 热重复领域和 MRE11-RAD50-NBS1 (MRN ) 的抑制的直接相互作用保护染色质免受异常 ATM 激活的伤害复杂依赖者的 ATM 招募。在 DNA 损坏之上, H1.2 通过它的 C 终点和进一步的 proteasomal 降级的 poly-ADP-ribosylation (PARylation ) 经历快速的 PARP1 依赖的染色质分离。由 PARylation 死了的变化妥协 ATM 激活和 DNA 损坏修理的 PARP1 弄空或 H1.2 的 H1.2 排水量的抑制,因此导致损害了房间幸存。一起拿,我们的调查结果建议连接器 histone H1.2 作为一个生理的障碍工作因为指向染色质的 ATM,和调停 PARylation 的活跃 H1.2 周转为柔韧的 ATM 激活和 DNA 损坏修理被要求。Zhiming Li Yinglu Li Ming Tang Bin Peng Xiaopeng Lu Qiaoyan Yang Qian Zhu Tianyun Hou Meiting Li Chaohua Liu Lina Wang Xingzhi Xu Ying Zhao Haiying Wang Yang Yang Wei-Guo Zhu 2018Cell Research2018,28,7:3
13Overview of the Solar Polar Orbit Telescope Project for Space Weather Mission显示文摘The Solar Polar ORbit Telescope(SPORT) project for space weather mission has been under intensive scientific and engineering background studies since it was incorporated into the Chinese Space Science Strategic Pioneer Project in 2011.SPORT is designed to carry a suite of remote-sensing and in-situ instruments to observe Coronal Mass Ejections(CMEs),energetic particles,solar high-latitude magnetism,and the fast solar wind from a polar orbit around the Sun.The first extended view of the polar regions of the Sun and the ecliptic enabled by SPORT will provide a unique opportunity to study CME propagation through the inner heliosphere,and the solar high-latitude magnetism giving rise to eruptions and the fast solar wind.Coordinated observations between SPORT and other spaceborne/ground-based facilities within the International Living With a Star(ILWS) framework can significantly enhance scientific output.SPORT is now competing for official selection and implementation during China's 13 th Five-Year Plan period of 2016-2020.XIONG Ming LIU Ying LIU Hao LI Baoquan ZHENG Jianhua ZHANG Cheng XIA Lidong ZHANG Hongxin RAO Wei CHEN Changya SUN Weiying WU Xia DENG Yuanyong HE Han JIANG Bo WANG Yuming WANG Chuanbing SHEN Chenglong ZHANG Haiying ZHANG Shenyi YANG Xuan SANG Peng WU Ji 2016空间科学学报2016,36,3:3
14Highly efficient fluoride removal from water using 2D metal-organic frameworks MIL-53(Al)with rich Al and O adsorptive centers显示文摘In this study,metal-organic framework MIL-53(Al)was synthesized and studied to understand the different mechanisms between normal MIL-53(Al)and 2D metal-organic framework MIL-53(Al)for removing fluoride.Comparatively,the 2D MIL-53(Al)had two-dimensional linear morphology rather than block shape,indicating more expose adsorptive sites than normal MIL-53(Al).The batch adsorption experiments were applied to investigate the performance of 2D MIL-53(Al),including pH,adsorption kinetics,and thermodynamics.The 2D MIL-53(Al)(75.50 mg/g)showed better adsorption capacity than normal MIL-53(Al)(35.63 mg/g).The adsorption process of 2D MIL-53(Al)followed the pseudo-firstorder model and Langmuir model.The adsorption mechanism of this material was further studied by using experimental characterization and density functional theory calculations in detail.The main adsorptive sites were Al and O in the 2D MIL-53(Al),and the relationship between fluoride binding with Al and O was HF^(-)_(2)>HF>F^(-).The species of fluoride were HF2,HF,F at different pH and concentrations.Hence,this study provides a significant way on the application of two-dimensional materials for removing fluoride.Lei Huang Zhihui Yang Sikpaam Issaka Alhassan Zhixuan Luo Baocheng Song Linfeng Jin Yixian Zhao Haiying Wang 2021Environmental Science and Ecotechnology2021,,4:3
15Scalable synthesis of Na_(3)V_(2)(PO_(4))_(3)/C with high safety and ultrahigh-rate performance for sodium-ion batteries显示文摘NASICON-type Na_(3)V_(2)(PO_(4))_(3) is a promising electrode material for developing advanced sodium-ion batteries.Preparing Na_(3)V_(2)(PO_(4))_(3) with good performance by a cost-effective and large-scale method is significant for industrial applications.In this work,a porous Na_(3)V_(2)(PO_(4))_(3)/C cathode material with excellent electrochemical performance is successfully prepared by an agar-gel combined with freeze-drying method.The Na_(3)V_(2)(PO_(4))_(3)/C cathode displayed specific capacities of 113.4 mAh·g^(-1),107.0 mAh·g^(-1) and 87.1 mAh·g^(-1) at 0.1 C,1 C and 10 C,respectively.For the first time,the 500-mAh soft-packed symmetrical sodium-ion batteries based on Na_(3)V_(2)(PO_(4))_(3)/C electrodes are successfully fabricated.The 500-mAh symmetrical batteries exhibit outstanding low temperature performance with a capacity retention of 83%at 0℃ owing to the rapid sodium ion migration ability and structural stability of Na_(3)V_(2)(PO_(4))_(3)/C.Moreover,the thermal runaway features are revealed by accelerating rate calorimetry(ARC)test for the first time.Thermal stability and safety of the symmetrical batteries are demonstrated to be better than lithium-ion batteries and some reported sodium-ion batteries.Our work makes it clear that the soft-packed symmetrical sodium ion batteries based on Na_(3)V_(2)(PO_(4))_(3)/C have a prospect of practical application in high safety requirement fields.Guijia Cui Hong Wang Fengping Yu Haiying Che Xiaozhen Liao Linsen Li Weimin Yang Zifeng Ma 2022Chinese Journal of Chemical Engineering2022,35,6:2
16The chromosome-level Stevia genome provides insights into steviol glycoside biosynthesis显示文摘Stevia(Stevia rebaudiana Bertoni)is well known for its very sweet steviol glycosides(SGs)consisting of a common tetracyclic diterpenoid steviol backbone and a variable glycone.Steviol glycosides are 150–300 times sweeter than sucrose and are used as natural zero-calorie sweeteners.However,the most promising compounds are biosynthesized in small amounts.Based on Illumina,PacBio,and Hi-C sequencing,we constructed a chromosome-level assembly of Stevia covering 1416 Mb with a contig N50 value of 616.85 kb and a scaffold N50 value of 106.55 Mb.More than four-fifths of the Stevia genome consisted of repetitive elements.We annotated 44,143 high-confidence protein-coding genes in the high-quality genome.Genome evolution analysis suggested that Stevia and sunflower diverged~29.4 million years ago(Mya),shortly after the whole-genome duplication(WGD)event(WGD-2,~32.1 Mya)that occurred in their common ancestor.Comparative genomic analysis revealed that the expanded genes in Stevia were mainly enriched for biosynthesis of specialized metabolites,especially biosynthesis of terpenoid backbones,and for further oxidation and glycosylation of these compounds.We further identified all candidate genes involved in SG biosynthesis.Collectively,our current findings on the Stevia reference genome will be very helpful for dissecting the evolutionary history of Stevia and for discovering novel genes contributing to SG biosynthesis and other important agronomic traits in future breeding programs.Xiaoyang Xu Haiyan Yuan Xiaqing Yu Suzhen Huang Yuming Sun Ting Zhang Qingquan Liu Haiying Tong Yongxia Zhang Yinjie Wang Chunxiao Liu Lei Wu Menglan Hou Yongheng Yang 2021Horticulture Research2021,8,1:2
17Separation and Anti-Hantaan Virus Activity of Extracts from Alternanthera philoxcroides in vitro and in vivo显示文摘A water-soluble substance was extracted from the Chi-nese herb, Alternanthera philoxcroides with hot water and alcohol. Aliquots of this initial extract were further fractionated by treat-ment with ether, ethyl acetate and alcohol respectively. The four extracts were assayed for anti-viral activity against three serum, Hantaan virus 114 (HV114),HV435 and A9 strains. Results show that the four extracts are capable of inhibiting Hantaan virus propagation, of which extract No.1 has the best efficiency. The three dosage of extract No.1, which are used upon three Hantaan virus serum IC50, are 153, 157, 154 μ?/mL. New-born mice were made to be infected with HV114 and then fed in vivo with extract No.1 on the 3rd, 10th and 14th days after being infected by the virus. The treatment continued for 8 days with a dosage of 2.5 g/kg. Result shows that survival rates of mice were 75%, 50% and 0, respectively. The median time to death (MTDs) of the three groups were 37, 30, 23 days.LIU Yingjuan YANG Zhanqiu DENG Haiying XIAO Hong QU Chunfeng 2007Wuhan University Journal of Natural Sciences2007,12,6:2
18Histones released by NETosis enhance the infectivity of SARS-CoV-2 by bridging the spike protein subunit 2 and sialic acid on host cells显示文摘Neutrophil extracellular traps(NETs)can capture and kill viruses,such as influenza viruses,human immunodeficiency virus(HIV),and respiratory syncytial virus(RSV),thus contributing to host defense.Contrary to our expectation,we show here that the histones released by NETosis enhance the infectivity of SARS-CoV-2,as found by using live SARS-CoV-2 and two pseudovirus systems as well as a mouse model.The histone H3 or H4 selectively binds to subunit 2 of the spike(S)protein,as shown by a biochemical binding assay,surface plasmon resonance and binding energy calculation as well as the construction of a mutant S protein by replacing four acidic amino acids.Sialic acid on the host cell surface is the key molecule to which histones bridge subunit 2 of the S protein.Moreover,histones enhance cell-cell fusion.Finally,treatment with an inhibitor of NETosis,histone H3 or H4,or sialic acid notably affected the levels of sgRNA copies and the number of apoptotic cells in a mouse model.These findings suggest that SARS-CoV-2 could hijack histones from neutrophil NETosis to promote its host cell attachment and entry process and may be important in exploring pathogenesis and possible strategies to develop new effective therapies for COVID-19.Weiqi Hong Jingyun Yang Jun Zou Zhenfei Bi Cai He Hong Lei Xuemei He Xue Li Aqu Alu Wenyan Ren Zeng Wang Xiaohua Jiang Kunhong Zhong Guowen Jia Yun Yang Wenhai Yu Qing Huang Mengli Yang Yanan Zhou Yuan Zhao Dexuan Kuang Junbin Wang Haixuan Wang Siyuan Chen Min Luo Ziqi Zhang Tiangi Lu Li Chen Haiying Que Zhiyao He Qiu Sun Wei Wang Guobo Shen Guangwen Lu Zhiwei Zhao Li Yang Jinliang Yang Zhenling Wang Jiong Li Xiangrong Song Lunzhi Dai Chong Chen Jia Geng Maling Gou Lu Chen Haohao Dong Yong Peng Canhua Huang Zhiyong Qian Wei Cheng Changfa Fan Yuquan Wei Zhaoming Su Aiping Tong Shuaiyao Lu Xiaozhong Peng Xiawei Wei 2022Cellular & Molecular Immunology2022,19,5:2
19Research on the Application of Time Structure Variation Analysis to the Jiashi-Bachu Earthquake Swarm Sequence显示文摘In 1997~2003,27 earthquakes with M≥5.0 occurred in the Jiashi-Bachu area of Xinjiang. It was a rare strong earthquake swarm activity. The earthquake swarm has three time segments of activity with different magnitudes in the years 1997, 1998 and 2003. In different time segments, the seismic activity showed strengthening-quiet changes in various degrees before earthquakes with M≥5.0. In order to delimitate effectively the precursory meaning of the clustering (strengthening) quiet change in sequence and to seek the time criterion for impending prediction, the nonlinear characteristics of seismic activity have been used to analyze the time structure characteristics of the earthquake swarm sequence, and further to forecast the development tendency of earthquake sequences in the future. Using the sequence catalogue recorded by the Kashi Station, and taking the earthquakes with M_S≥5.0 in the sequence as the starting point and the next earthquake with M_S=5.0 as the end, statistical analysis has been performed on the time structure relations of the earthquake sequence in different stages. The main results are as follows: (1) Before the major earthquakes with M≥5.0 in the swarm sequence, the time variation coefficient (δ-value) has abnormal demonstrations to different degrees. (2) Within 10 days after δ≈1, occurrence of earthquakes with M≥5.0 in the swarm is very possible. (3) The time variation coefficient has three types of change. (4) The change process before earthquakes with M5.0 is similar to that before earthquakes with M6.0, with little difference in the threshold value. In the earthquake swarm sequence, it is difficult to delimitate accurately the attribute of the current sequences (foreshock or aftershock sequence) and to judge the magnitude of the follow-up earthquake by δ-value. We can only make the judgment that earthquakes with M5.0 are likely to occur in the sequence. (5) The critical clustering characteristics of the sequence are hierarchical. Only corresponding to a certain magnitude can the sequence have the variation state of critical clustering. (6) The coefficient of the time variation has a clear meaning in physics. After the clustering-quiet state of earthquake activity has appeared, it can describe clearly the randomness of the seismogenic system. Furthermore, it can efficiently clarify whether or not the clustering quiescence variation is of some prognostic meaning. In the case that the earthquake frequency attenuation is essentially normal (h>1) and there is no remarkable clustering-quiescence state, it is still possible to discover the abnormal change of the sequence from the time variation coefficient. On the contrary, in the later period of swarm activity, after the appearance of many seismic quiescence phenomena, this coefficient did not appear abnormally, even when h<1, suggesting that the δ-value diagnosis is more universal.Yang Xin Long Haiying Shangguan Wenming Nie Xiaohong 2008Earthquake Research in China2008,22,3:2
20Genetic relationship and pedigree of Chinese watermelon varieties based on diversity of perfect SNPs显示文摘Watermelon(Citrullus lanatus)is one of the world’s most important fruit crops,and China produces the most watermelons in the world.Recently,a watermelon variome consisting of 414 key resequenced accessions was reported.However,the genetic relationships and pedigree of Chinese watermelon varieties in the seed market remain unclear.In this study,241 evenly distributed perfect single nucleotide polymorphisms(SNPs)derived from the watermelon variome were selected for variety identification.The diversity of 247 Chinese watermelon varieties was identified based on their SNP genotypes.The 247 watermelon varieties were clustered into five subpopulations:the East Asian ecotype,intermediate ecotype,small fruit with red flesh ecotype,small fruit with yellow flesh ecotype,and American ecotype.We further established the pedigree of four subpopulations,of which JingXinNo.1,ZaoChunHongYu,HuangXiaoYu and XiaoLan,and Sugarlee were the main doner of the East Asian ecotype,small fruit with red flesh ecotype,small fruit with yellow flesh ecotype,and American ecotype,respectively.Thirty-two core SNPs were selected and applied in watermelon variety identification.They were also validated by the Kompetitive allele-specific PCR(KASPar)platform.The present study furthered our understanding of the genetic relationships and pedigree of watermelon varieties in China,and will help to manage the plant variety protection in watermelon.Jingjing Yang Jian Zhang Hushan Du Hong Zhao Aijun Mao Xiaofei Zhang Luo Jiang Haiying Zhang Changlong Wen Yong Xu 2022Horticultural Plant Journal2022,8,4:2
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