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| 1 | Application of a catch-based method for stock assessment of three important fisheries in the East China Sea显示文摘Most fisheries in China do not have maximum sustainable yield(MSY) estimates due to limited and poor data.Therefore, finding a common method to estimate MSY or total allowable catch(TAC) for fishery management is necessary. MSYs of three important fisheries in the East China Sea were evaluated through a catch-based model.Estimates for intrinsic rate of increase(r) and five levels of process error were considered. Results showed hairtail Trichiurus japonicas(Temminck and Schlegel) and small yellow croaker Larimichthys polyactis(Bleeker) fisheries experienced overfishing from the mid-1990 s to the early 2000 s, and the suggested TACs were 55.8×10~4 t and9.06×10~4 t, respectively. Decades of overfishing in wintering and spawning grounds of large yellow croaker Larimichthys crocea(Richardson) caused the fishery's collapse in the 1980 s, and it has not recovered until today.The Catch–MSY model generated similar estimated MSYs with other methods and may be a useful choice for the assessment of regional stocks in China. | ZHANG Kui ZHANG Jun XU Youwei SUN Mingshuai CHEN Zuozhi YUAN Meng | 2018 | Acta Oceanologica Sinica2018，37，2： | 14 |
| 2 | Strengths, weaknesses, opportunities and threats (SWOT) analysis of reinitiation into methamphetamine abusers: qualitative findings from an exploration of methamphetamine abusers in Shanghai, China显示文摘Background Despite high relapse rate among methamphetamine (MA) abusers, there still have been little empirical data to date detecting the risk factors related to craving and relapse from the perspective of MA abusers. Therefore, the aim of this study was to use qualitative research methods exploring the strengths, weaknesses, opportunities and threat factors that could facilitate or impede individuals' abstinence in a real-life context from the perspectives of MA abusers. Aim To use qualitative research methods exploring the strengths, weaknesses, opportunities and threat factors relating to individuals' abstinence in a real-life context. Method Semistructured interviews were conducted with 32 MA abusers recruited in Shanghai guided by open-ended questions on narrating the real-life catalysts and inhibitors related to craving, initiation, relapse and abstinence. All data were transcribed verbatim and analysed using a strengths, weaknesses, opportunities and threats (SWOT) analysis. Results The results of the SWOT analysis revealed that contextual factors including peer influence, prevalence and availability of MA, familiar venue of MA use, discrimination, sexual behaviours, alcohol, emotional states and their attitudes towards smoking MA were important factors that contribute to reinitiation and relapse. Surveillance systems, antidrug social workers, vocational skills trainings, moving to another city and family responsibility might serve as counter measures targeti叩 those mentioned weaknesses and threats above. Conclusion This SWOT analysis highlights the complex nature of relapse. Comprehensive interventions strengtheni叩 coping skills such as virtual reality techniques are desperately needed to facilitate individuals1 sustained abstinence. | Youwei Zhu Na Zhong Hang Su Xiaolu Ruan Jiayi Bao Lei Zhang Jiang Du Ding Xu Rongjie Ding Ke Xiao Min Zhao | 2019 | General Psychiatry2019，32，3： | 9 |
| 3 | Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins显示文摘The Omicron BA.2 variant has become a dominant infective strain worldwide.Receptor binding studies show that the Omicron BA.2 spike trimer exhibits 11-fold and 2-fold higher potency in binding to human ACE2 than the spike trimer from the wildtype(WT)and Omicron BA.1 strains.The structure of the BA.2 spike trimer complexed with human ACE2 reveals that all three receptor-binding domains(RBDs)in the spike trimer are in open conformation,ready for ACE2 binding,thus providing a basis for the increased infectivity of the BA.2 strain.JMB2002,a therapeutic antibody that was shown to efficiently inhibit Omicron BA.1,also shows potent neutralization activities against Omicron BA.2.In addition,both BA.1 and BA.2 spike trimers are able to bind to mouse ACE2 with high potency.In contrast,the WT spike trimer binds well to cat ACE2 but not to mouse ACE2.The structures of both BA.1 and BA.2 spike trimer bound to mouse ACE2 reveal the basis for their high affinity interactions.Together,these results suggest a possible evolution pathway for Omicron BA.1 and BA.2 variants via a human-cat-mouse-human circle,which could have important implications in establishing an effective strategy for combating SARS-CoV-2 viral infections. | Youwei Xu Canrong Wu Xiaodan Cao Chunyin Gu Heng Liu Meriting Jiang Xiaoxi Wang Qingning Yuan Kai Wu Jia Liu Deyi Wang Xianqing He Xueping Wang Su-Jun Deng H.Eric Xu Wanchao Yin | 2022 | Cell Research2022，32，7： | 6 |
| 4 | Aerosol light absorption in a coastal city in Southeast China:Temporal variations and implications for brown carbon显示文摘Light-absorbing carbonaceous aerosols including black carbon(BC) and brown carbon(BrC)play significant roles in atmospheric radiative properties. One-year measurements of aerosol light absorption at multi-wavelength were continuously conducted in Xiamen,southeast of China in 2014 to determine the light absorption properties including absorption coefficients(σabs) and absorption ?ngstr?m exponent(AAE) in the coastal city.Light absorptions of BC and BrC with their contributions to total light absorption were further quantified. Mean σabsat 370 nm and 880 nm were 56.6 ± 34.3 and 16.5 ± 11.2 Mm-1,respectively. σabspresented a double-peaks diurnal pattern with the maximum in the morning and the minimum in the afternoon. σabswas low in warm seasons and high in cold seasons. AAE ranged from 0.26 to 2.58 with the annual mean of 1.46, implying that both fossil fuel combustion and biomass burning influenced aerosol optical properties. σabsof BrC at 370 nm was 24.0 ± 5.7 Mm-1, contributing 42% to the total absorption. The highest AAE(1.52 ± 0.02) and largest BrC contributions(47% ± 4%) in winter suggested the significant influence of biomass burning on aerosol light absorption. Long-distance air masses passing through North China Plain and the Yangtze River Delta led to high AAE and BrC contributions. High AAE value of 1.46 in July indicated that long-range transport of the air pollutants from intense biomass burning in Southeast Asia would affect aerosol light absorption in Southeast China. The study will improve the understanding of light absorption properties of aerosols and the optical impacts of BrC in China. | Yuqing Qiu Xin Wu Yanru Zhang Lingling Xu Youwei Hong Jinsheng Chen Xiaoqiu Chen Junjun Deng | 2019 | Journal of Environmental Sciences2019，31，6： | 5 |
| 5 | Zircon U-Pb Ages and Sr-Nd-Hf Isotopic Characteristics of the Huichizi Granitic Complex in the North Qinling Orogenic Belt and Their Geological Significance显示文摘The Huichizi granite complex is the largest Paleozoic I-type intrusion located in the North Qinling orogenic belt(NQB). In this study, we present systematic geochemical element data, zircon U-Pb ages, Lu-Hf isotopic data, and Sr-Nd isotopic data for the Huichizi granites. In terms of mineral and chemical compositions, these granites are biotite monzonitic and alkali-feldspar granites, both of which are characterized by high SiO 2 and total alkali contents and low Mg O, Ti O2, and TFeO contents. These granites are weakly peraluminous(A/CNK values are 1–1.06 for biotite monzonitic granites and 1.04–1.09 for alkali-feldspar granites) and possess the geochemical characteristics of adakitic rocks, e.g., high Sr contents(319 ppm–633 ppm), Sr/Y ratios(18.5–174), and(La/Yb)N ratios(17.6–57) and low MgO(0.04 wt.%–0.83 wt.%), Y(3.0 ppm–17.2 ppm), and heavy rare-earth element(HREE) contents. This indicates that these rocks were most likely derived from the partial melting of a thickened lower crust. In situ zircon U-Pb dating of these granites yields Early Caledonian ages(437 Ma for biotite monzonitic granites and 424 Ma for alkali-feldspar granites), indicating that the Huichizi granitic complex is the product of multi-periodic magmatism. The positive but varying zircon εHf(t) values(+0.6 to +8.5) suggest that this thickened lower crust was mainly juvenile, i.e., accreted from depleted mantle during the Neo-Mesoproterozoic Period, but involved the ancient recycled crust. Biotite monzonitic granites formed during crust thickening at the extrusion stage, whereas the alkali granites formed during crust thickening at the extension stage(post extrusion). The Huichizi granite complex witnessed the process of extrusion to extension because of the collision between the NCB and the Qinling microcontinent in the Caledonian. | Youwei Chen Ruizhong Hu Xianwu Bi Shaohua Dong Yue Xu Ting Zhou | 2018 | Journal of Earth Science2018，29，3： | 5 |
| 6 | The PHD1 finger of KDM5B recognizes unmodified H3K4 during the demethylation of histone H3K4me2/3 by KDM5B显示文摘KDM5B 是 histone H3K4me2/3 demethylase。KDM5B 的 PHD1 领域为 demethylation 是批评的,但是位于这个领域的行动下面的机制是不清楚的。在这份报纸,我们观察了那 PHD1 < 潜水艇 class= “ a-plus-plus ” > KDM5B 与 unmethylated H3K4me0 交往。我们 PHD1 的 NMR 结构 < 潜水艇 class= “ a-plus-plus ” > 在有 H3K4me0 的建筑群的 KDM5B 表明有约束力的模式与另外的报导哲学博士手指的稍微不同。由在接口(L325A/D328A ) 的残余上的两倍变化的这个相互作用的混乱减少在在约 50% 的房间和增加的 KDM5B 的 H3K4me2/3 demethylation 活动肿瘤 suppressor 基因由的 transcriptional 压抑近似双重。这些调查结果暗示那 PHD1 < 潜水艇 class= “ a-plus-plus ” > KDM5B 可以帮助在目标基因维持 KDM5B 调停 KDM5B 的 demethylation 活动。 | Yan Zhang Huirong Yang Xue Guo Naiyan Rong Yujiao Song Youwei Xu Wenxian Lan Xu Zhang Maili Liu Yanhui Xu Chunyang Cao | 2014 | Protein & Cell2014，5，11： | 3 |
| 7 | Room temperature ferromagnetism of Ni, (Ni, Li), (Ni, N)-doped ZnO thin films显示文摘Ni-doped ZnO thin films (Ni concentration up to 10 mol%) were generated on Si (100) substrates by a sol-gel technique. The films showed wurtzite structure and no other phase was found. The chemical state of Ni was found to be bivalent by X-ray photoelectron spectroscopy. The results of magnetic measurements at room temperature indicated that the films were ferromagnetic, and magnetic moment decreased with rise of Ni concentration. The magnetization of Ni (10 mol%)-doped ZnO film annealed in nitrogen was lower than that annealed in argon, suggesting that the density of defects had an effect on ferromagnetism. | YE XiaoJuan SONG HaiAn ZHONG Wei QI XiaoSi XU MeiHua JIN ChangQing YANG ZaiXin AU ChakTong DU YouWei | 2010 | 中国科学:技术科学2010，40，2： | 2 |
| 8 | Aberrant expression of BDNF might serve as a candidate target for cocaine- induced psychosis: insights from bioinformatics analysis and microarray validation显示文摘Background Cocaine use disorder(CUD)and associated psychosis are major public health issues worldwide,along with high relapse outcome and limited treatment options.Exploring the molecular mechanisms underlying cocaine-induced psychosis(CIP)could supply integrated insights for understanding the pathogenic mechanism and potential novel therapeutic targets.Aims The aim of the study was to explore common alterations of CUD-schizophrenia target genes and identify core risk genes contributing to CIP through data mining and network pharmacology approach.Methods Target genes of CUD were obtained from GeneCards,Comparative Toxicogenomics Database,Swiss Target Prediction platform and PubChem.Schizophrenia-related target genes were derived from DisGeNET,GeneCards,MalaCards and Online Mendelian Inheritance in Man databases.Then,the overlap genes of these two sets were regarded as risk genes contributing to CIP.Based on these CUD-schizophrenia target genes,functional annotation and pathway analysis were performed using the clusterProfiler package in R.Protein-protein interaction network construction and module detection were performed based on the Search Tool for the Retrieval of Interacting Genes(STRING)database and Cytoscape software.Gene expression datasets GSE54839 and GSE93577 were applied for data validation and diagnostic capacity evaluation of interested hub genes.Results A total of 165 CUD-schizophrenia target genes were obtained.These genes were mainly contributing to chemical synaptic transmission,neuropeptide hormone activity,postsynaptic membrane and neuroactive ligand-receptor interaction pathway.Network analysis and validation analysis indicated that BDNF might serve as an important risk gene in mediating CIP.Conclusions This study generates a holistic view of CIP and provides a basis for the identification of potential CUD-schizophrenia target genes involved in the development of CIP.The abnormal expression of BDNF would be a candidate therapeutic target underlying the pathogenesis of CUD and associated CIP. | Youwei Zhu Yan Zhao Xiaomin Xu Hang Su Xiaotong Li Na Zhong Haifeng Jiang Jiang Du Min Zhao | 2021 | General Psychiatry2021，34，5： | 2 |
| 9 | Generation of selectable marker-free soft transgenic rice with transparent kernels by downregulation of SSSⅡ-2显示文摘The amylose content(AC)of rice endosperm starch varies from 0 to 35%,and is associated with rice cooking and eating quality.Soft rice has low AC,generally between 6%and 15%,and its eating quality is high whether it is consumed hot or cold.However,the appearance quality of current soft rice cultivars needs to be improved,especially opaque endosperm.Conventional genetic engineering has improved some agronomic traits of soft rice varieties,but not endosperm appearance.In the present study,a RNAi construct of the soluble starch synthase II-2(SSSII-2)and the hygromycin phosphotransferase(HPT)gene were introduced into an elite japonica rice variety,Kangtiaowuyunjing(KWY8)by co-transformation.Several selectable marker-free(SMF)transgenic lines were obtained,and SSSII-2 expression was significantly downregulated in selected transgenic lines,resulting in lower AC of the endosperm.The physicochemical properties of the transgenic rice kernels,including gel consistency(GC)and rapid visco analyzer(RVA)profile,differed significantly from those of wild-type rice and were similar to those of a soft rice variety,Nanjing 46(NJ46).These findings indicate that the cooking,eating,and processing qualities of transgenic rice are comparable to those of NJ46.However,the transgenic rice endosperm retained a transparent appearance under low-moisture conditions.Thus,SMF SSSII-2 RNAi rice provides a resource for breeding soft rice with transparent endosperm. | Zhihao Xu Meimei Yu Youwei Yin Cenwen Zhu Wen Ji Changquan Zhang Qianfeng Li Honggen Zhang Shuzu Tang Hengxiu Yu Qiaoquan Liu | 2020 | The Crop Journal2020，8，1： | 2 |
| 10 | Synthesis and Characterization of CoAPO-11 Molecular Sieve from a Non-aqueous System显示文摘IntroductionFolowingthesynthesesofaluminophosphatefamilyofmolecularsieves(AlPO4-n)in1982[1],aseriesofMeAPO-n(Me=Mg,Mn,CoorFe,... | JIAO Xiuling, YAO Youwei, PANG Wenqin** and XU Ruren (Department of Chemistry, Jilin University, Changchun, 130023) | 1999 | Chemical Research in Chinese Universities1999，15，2： | 1 |
| 11 | Protection of the flavonoid fraction from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice显示文摘 | Shuai Zhang Binan Lu Xu Han Lina Xu Yan Qi Lianhong Yin Youwei Xu Yanyan Zhao Kexin Liu Jinyong Peng | 2012 | Food and Chemical Toxicology2012，，： | 1 |
| 12 | Protective effects of the total saponins from Dioscorea nipponica Makino against carbon tetrachloride-induced liver injury in mice through suppression of apoptosis and inflammation显示文摘 | Hao Yu Lingli Zheng Lianhong Yin Lina Xu Yan Qi Xu Han Youwei Xu Kexin Liu Jinyong Peng | 2014 | International Immunopharmacology2014，，： | 1 |
| 13 | Radiation synthesis and Cr(VI) removal of cellulose microsphere adsorbent显示文摘 | Youwei Zhang Ling Xu Long Zhao Jing Peng Cancan Li Jiuqiang Li Maolin Zhai | 2012 | Carbohydrate Polymers2012，，3： | 1 |
| 14 | Behind the Scences of the Xi'an Incident: The Case of the Lixingshe显示文摘 | Xu Youwei & Phil Billingsley | 1998 | The China Quarterly1998，6，154： | 1 |
| 15 | Experimental exploration of five-qubit quantum error-correcting code with superconducting qubits显示文摘Quantum error correction is an essential ingredient for universal quantum computing.D espite tremendous experimental efforts in the study of quantum error correction,to date,there has been no demonstration in the realis ation of universal quantum error-correcting code,with the subsequent verification of all key features including the identification of an arbitrary physical error,the capability for transversal manipulation of the logical state and state decoding.To address this challenge,we experimentally realise the [5,1,3]code,the so-called smallest perfect code that permits corrections of generic single-qubit errors.In the experiment,having optimised the encoding circuit,we employ an array of superconducting qubits to realise the [5,1,3] code for several typical logical states including the magic state,an indispensable resource for realising non-Clifford gates.The encoded states are prepared with an average fidelity of 57.1(3)% while with a high fidelity of 98.6(1)% in the code space.Then,the arbitrary single-qubit errors introduced manually are identified by measuring the stabilisers.We further implement logical Pauli operations with a fidelity of 97.2(2)% within the code space.Finally,we realise the decoding circuit and recover the input state with an overall fidelity of 74.5(6)%,in total with 92 gates.Our work demonstrates each key aspect of the [5,1,3] code and verifies the viability of experimental realisation of quantum error-correcting codes with superconducting qubits. | Ming Gong Xiao Yuan Shiyu Wang Yulin Wu Youwei Zhao Chen Zha Shaowei Li Zhen Zhang Qi Zhao Yunchao Liu Futian Liang Jin Lin Yu Xu Hui Deng Hao Rong He Lu Simon C.Benjamin Cheng-Zhi Peng Xiongfeng Ma Yu-Ao Chen Xiaobo Zhu Jian-Wei Pan | 2022 | National Science Review2022，9，1： | 1 |
| 16 | Change of phase state during multi-cycle injection and production process of condensate gas reservoir based underground gas storage显示文摘Based on the differences in production mode and operation process between gas storage and gas reservoir,we established a phase balance test procedure and a theoretical simulation model of phase balance during multi-cycles of injection and production of underground gas storage(UGS)rebuilt from condensate gas reservoir to study the phase characteristics of produced and remaining fluids during multi-cycles of injection and production.Take condensate reservoir gas storage as example,the composition of produced fluid and remaining fluid,phase state of remaining fluid,retrograde condensate saturation and condensate recovery degree in the process of multi-cycles of injection-production were studied through multi-cycle injection-production experiment and phase equilibrium theory simulation.The injected gas could greatly improve the recovery of condensate oil in the gas reservoir,and the condensate oil recovery increased by 42% after 5 cycles of injection and production;the injected gas had significant evaporative and extraction effects on the condensate,especially during the first two cycles;the condensate oil saturation of the formation decreased with the increase of injection-production cycles,and the condensate oil saturation after multi-cycles of injection-production was almost 0;the storage capacity increased by about 7.5% after multi-cycles of injection and production,and the cumulative gas injection volume in the 5 th cycle increased by about 25%compared with that in the 1 st cycle. | TANG Yong LONG Keji WANG Jieming XU Hongcheng WANG Yong HE Youwei SHI Lei ZHU Huayin | 2021 | Petroleum Exploration and Development2021，48，2： | 1 |
| 17 | Structural insights into ligand binding and activation of the human thyrotropin-releasing hormone receptor显示文摘Dear Editor,The thyrotropin-releasing hormone(TRH)is the initlal hormone of the hypothalamo-pituitary-thyroid axis(HPT),a signaling cascade required for metabolic homeostasis and development in vertebrates.TRH is a tripeptide hormone(pGlu-His-Pro-NH2)that is synthesized in the hypothalamus and activates thyrotropin-releasing hormone receptor(TRHR),a member of class A G protein-coupled receptor(GPCR). | Youwei Xu Hongmin Cai Chongzhao You Xinheng He Qingning Yuan Hualiang Jiang Xi Cheng Yi Jiang H.Eric Xu | 2022 | Cell Research2022，32，9： | 0 |
| 18 | Development and Research on the Internet Resources Aggregation Platform显示文摘We proposed an Internet resource aggregation platform based on semantic web. The platform includes an Web Ontology Language(OWL) ontology design toolkit(VO-Editor) and a selective inference algorithm engine so that it can visually editing ontology and using novel selective reasoning for information aggregation. We introduce the VO-Editor and the principle of selective inference algorithm. At last a case of budget travel system is used to interpret the approach of Internet resources aggregation by this platform. | XU Youwei TANG Shengqun YANG Yan XU Yang LI Ling | 2007 | Wuhan University Journal of Natural Sciences2007，12，2： | 0 |
| 19 | Combining magnetocaloric and elastocaloric effects in a Ni45Co5Mn37In13 alloy显示文摘1.Introduction Refrigeration plays an essential role in nowadays society.However,conventional refrigeration based on vapor compression cooling shows high energy consumption,complicated structure and even environmental pollution.Searching for an environmentalfriendly and energy-saving refrigeration technology has become a matter of concern[1,2].In the past few decades,the solid-state refrigeration technologies mainly represented by magnetocaloric effect(MCE),electrocaloric effect(ECE)and elastocaloric effect(e CE)have been regarded as promising candidate to replace traditional vapor compression refrigeration technology owing to environmental friendliness and high efficiency[1-9]. | Pengtao Cheng Zhenjia Zhou Jiaxing Chen Zongbin Li Bo Yang Kun Xu Zhe Li Jun Li Zhengming Zhang Dunhui Wang Suxin Qian Youwei Du | 2021 | Journal of Materials Science & Technology2021，，35： | 0 |
| 20 | Sources appointment and health risks of PM_(2.5)-bound trace elements in a coastal city of southeastern China显示文摘To gain a comprehensive understanding of sources and health risks of trace elements in an area of China with high population densities and low PM_(2.5)concentrations,15 trace elements(Al,K,Ca,Ti,V,Cr,Mn,Fe,Ni,Cu,Zn,As,Sn,Ba,Pb)in PM_(2.5)were monitored from December 2020 to November 2021 in a representative city,Xiamen.The concentrations of trace elements in Xiamen displayed an obvious seasonal variation and were dominated by K,Fe,Al,Ca and Zn.Based on Positive Matrix Factorization analysis,source appointment revealed that the major sources of trace elements in Xiamen were traffic,dust,biomass and firework combustion,industrial manufacture and shipping emission.According to health risk assessment combined with the source appointment results,it indicated that the average noncarcinogenic risk was below the threshold and cancer risk of four hazardous metals(Cr,Ni,As,Pb)exceeded the threshold(10^(-6)).Traffic-related source had almost half amount of contribution to the health risk induced by PM_(2.5)-bound trace elements.During the dust transport period or Spring Festival period,the health risks exceeded an acceptable threshold even an order of magnitude higher,suggesting that the serious health risks still existed in low PM_(2.5)environment at certain times.Health risk assessment reminded that the health risk reduction in PM_(2.5)at southeastern China should prioritize traffic-related hazardous trace elements and highlighted the importance of controlling vehicles emissions in the future. | Ziyi Lin Xiaolong Fan Gaojie Chen Youwei Hong Mengren Li Lingling Xu Baoye Hu Chen Yang Yanting Chen Zhiqian Shao Jinsheng Chen | 2024 | Journal of Environmental Sciences2024，，4： | 0 |
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