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| 1 | Glutamate synthase 1 is involved in iron-deficiency response and long-distance transportation in Arabidopsis显示文摘Iron is an essential microelement for plant growth.After uptake from the soil,iron is chelated by ligands and translocated from roots to shoots for sub-sequent utilization.However,the number of ligands in-volved in iron chelation is unclear.In this study,we identified and demonstrated that GLU1,which encodes a ferredoxin-dependent glutamate synthase,was involved in iron homeostasis.First,the expression of GLU1 was strongly induced by iron deficiency condition.Second,lesion of GLU1 results in reduced transcription of many iron-deficiency-responsive genes in roots and shoots.The mutant plants revealed a decreased iron concentration in the shoots,and displayed severe leaf chlorosis under the condition of Fe limitation,compared to wild-type.Third,the product of GLU1,glutamate,could chelate iron in vivo and promote iron transportation.Last,we also found that supplementation of glutamate in the medium can alleviate cadmium toxicity in plants.Overall,our results provide evidence that GLU1 is involved in iron homeo-stasis through affecting glutamate synthesis under iron deficiency conditions in Arabidopsis. | Man Cui Mengjun Gu Yaru Lu Yue Zhang Chunlin Chen Hong‐Qing Ling Huilan Wu | 2020 | Journal of Integrative Plant Biology2020，62，12： | 2 |
| 2 | Fast Distance Protection Scheme for Wind Farm Transmission Lines Considering R-L and Bergeron Models显示文摘The distributed capacitance of the line becomes larger as the scale of wind farms,the transmission voltage level,and the transmission distance increase.Hence,the error of the traditional time-domain distance protection scheme based on the R-L model,which ignores the distributed capacitance of the line,becomes unacceptable.Therefore,the error of the time-domain fault location method based on the R-L model,especially the maximum error range,is theoretically analyzed in this paper.On this basis,a novel fault location method based on the RL and Bergeron models is proposed.Then,a fast time-domain distance protection scheme is designed.In the proposed scheme,the error in the fitting calculation is used to construct a weight matrix,and an algorithm for solving the time-domain differential equations is designed to improve the calculation speed and stability.Compared with the traditional frequency-domain distance protection scheme,the proposed scheme is independent of the power supply characteristics;thus,it is suitable for wind farm transmission lines.In addition,compared with the traditional method based on the R-L model,the proposed scheme effectively avoids the negative influence of the distributed capacitance of the line,which significantly improves the operating speed.Different types of faults are simulated by PSCAD/EMTDC to verify the effectiveness and superiority of the proposed scheme. | Zepeng Hu Bin Li Yuping Zheng Tonghua Wu Jiawei He Bin Yao Yaru Sheng Wei Dai Xindong Li | 2023 | Journal of Modern Power Systems and Clean Energy2023，11，3： | 2 |
| 3 | Image encryption combining multiple generating sequences controlled fractional DCT with dependent scrambling and diffusion显示文摘 | Yaru Liang Guoping Liu Nanrun Zhou Jianhua Wu | 2015 | Journal of Modern Optics2015，，4： | 1 |
| 4 | A capillary liquid chromatographic/tandem mass spectrometric method for the quantification of 7-aminohutyric acid in human plasma and cerebrospinal fluid显示文摘 | SONG Yaru WU Mingshen DIRK M D | 2005 | Journal of Chromatography B2005，814，2： | 1 |
| 5 | Role of local coordination in bimetallic sites for oxygen reduction: A theoretical analysis显示文摘Understanding of the oxygen reduction reaction(ORR)mechanism for single atom catalysts is pivotal for the rational design of non-precious metal cathode materials and the commercialization of fuel cells.Herein,a series of non-precious metal electrocatalysts based on nitrogen-doped bimetallic(Fe and Co)carbide were modeled by density functional theory calculations to predict the corresponding reaction pathways.The study elucidated prior oxygen adsorption on the Fe atom in the dual site and the modifier role of Co atoms to tune the electronic structures of Fe.The reaction activity was highly correlated with the bimetallic center and the coordination environment of the adjacent nitrogen.Interestingly,the preadsorption of*OH resulted in the apparent change of metal atoms'electronic states with the d-band center shifting toward the Fermi level,thereby boosting reaction activity.The result should help promote the fundamental understanding of active sites in ORR catalysts and provide an effective approach to the design of highly efficient ORR catalysts on an atomic scale. | Yuqi Yang Hao Zhang Zhaofeng Liang Yaru Yin Bingbao Mei Fei Song Fanfei Sun Songqi Gu Zheng Jiang Yuen Wu Zhiyuan Zhu | 2020 | Journal of Energy Chemistry2020，29，5： | 1 |
| 6 | A new blue light-emitting material显示文摘 | Gui Yu Liu Yunqi Song Yaru Wu Xia Zhu Daoben | 2001 | Synthetic Metals2001，117，： | 1 |
| 7 | Intraspecific and interspecific variation in Setaria revealed by RAPD analysis显示文摘 | Yu Li Jizeng Jia Yaru Wang Shuzhi Wu | 1998 | Genetic Resources and Crop Evolution1998，，3： | 1 |
| 8 | Image encryption based on compressed sensing and variable parameter chaotic map显示文摘 | LIANG Yaru WU Jianhua | 2015 | Journal of Photoelectron Laser2015，26，3： | 1 |
| 9 | Exploring the catalytic function and active sites of a novel C-glycosyltransferase from Anemarrhena asphodeloides显示文摘Anemarrhena asphodeloides is an immensely popular medicinal herb in China,which contains an abundant of mangiferin.As an important bioactive xanthone C-glycoside,mangiferin possesses a variety of pharmacological activities and is derived from the cyclization reaction of a benzophenone C-glycoside(maclurin).Biosyntheti-cally,C-glycosyltransferases are critical for the formation of benzophenone C-glycosides.However,the benzo-phenone C-glycosyltransferases from Anemarrhena asphodeloides have not been discovered.Herein,a promiscuous C-glycosyltransferase(AaCGT)was identified from Anemarrhena asphodeloides.It was able to catalyze efficiently mono-C-glycosylation of benzophenone,together with di-C-glycosylation of dihydrochalcone.It also exhibited the weak O-glycosylation or potent S-glycosylation capacities toward 12 other types of flavonoid scaffolds and a simple aromatic compound with–SH group.Homology modeling and mutagenesis experiments revealed that the glycosylation reaction of AaCGT was initiated by the conserved residue H23 as the catalytic base.Three critical residues H356,W359 and D380 were involved in the recognition of sugar donor through hydrogen-bonding interactions.In particular,the double mutant of F94W/L378M led to an unexpected enzy-matic conversion of mono-C-to di-C-glycosylation.This study highlights the important value of AaCGT as a potential biocatalyst for efficiently synthesizing high-value C-glycosides. | Jia Huang Yaru She Jingyang Yue Yidu Chen Yu Li Jing Li Yonger Hu Deying Yang Jiabo Chen Lu Yang Zhongqiu Liu Ruibo Wu Pengfei Jin Lixin Duan | 2022 | Synthetic and Systems Biotechnology2022，7，1： | 1 |
| 10 | The role of cell death in SARS-CoV-2 infection显示文摘Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),showing high infectiousness,resulted in an ongoing pandemic termed coronavirus disease 2019(COVID-19).COVID-19 cases often experience acute respiratory distress syndrome,which has caused millions of deaths. | Cui Yuan Zhenling Ma Jiufeng Xie Wenqing Li Lijuan Su Guozhi Zhang Jun Xu Yaru Wu Min Zhang Wei Liu | 2023 | Signal Transduction and Targeted Therapy2023，8，10： | 0 |
| 11 | A review of monitoring,calculation,and simulation methods for ground subsidence induced by coal mining显示文摘Subsidence data acquisition methods are crucial to mining subsidence research and an essential component of achieving the goal of environmentally friendly coal mining.The origin and history of the existing methods of field monitoring,calcula-tion,and simulation were introduced.It summarized and analyzed the main applications,flaws and solutions,and improve-ments of these methods.Based on this analysis,the future developing directions of subsidence data acquisition methods were prospected and suggested.The subsidence monitoring methods have evolved from conventional ground monitoring to combined methods involving ground-based,space-based,and air-based measurements.While the conventional methods are mature in technology and reliable in accuracy,emerging remote sensing technologies have obvious advantages in terms of reducing field workload and increasing data coverage.However,these remote sensing methods require further technological development to be more suitable for monitoring mining subsidence.The existing subsidence calculation methods have been applied to various geological and mining conditions,and many improvements have already been made.In the future,more attention should be paid to unifying the studies of calculation methods and mechanical principles.The simulation methods are quite dependent on the similarity of the model to the site conditions and are generally used as an auxiliary data source for subsidence studies.The cross-disciplinary studies between subsidence data acquisition methods and other technologies should be given serious consideration,as they can be expected to lead to breakthroughs in areas such as theories,devices,software,and other aspects. | Yinfei Cai Yutian Jin Zuoyang Wang Tao Chen Yaru Wang Weiyu Kong Wu Xiao Xiaojing Li Xugang Lian Haifeng Hu | 2023 | International Journal of Coal Science & Technology2023，10，3： | 0 |
| 12 | Evaluation of FGF10 as a candidate gene for high myopia in a Han Chinese population显示文摘Background:Fibroblast growth factor 10(FGF10)is implicated in the growth and development of the eye.Four singles nucleotide polymorphisms(SNPs)in the FGF10 gene(including rs1384449,rs339501,rs12517396 and rs10462070)were found to be associated with extreme myopia(EM,refractive error≤−10.0 diopters)in Japanese and Chinese Taiwan population.This case-control association study was conducted to explore the relationship between these four SNPs and high myopia in a western Chinese population.Methods:A total of 869 high myopia patients(HM,including 485 EM patients)and 899 healthy controls were recruited.These four SNPs were genotyped using the ABI SNaPshot method.Five genetic models(allelic,homozygous,heterozygous,dominant,and recessive)were applied to further evaluate the possible correlation between the SNPs and high myopia.The linkage-disequilibrium block(LD)structure was tested by Haploview Software.Results:In our study,no statistically significant differences were found between HM/EM patients and controls after Bonferroni multiple-correction(P>0.05)in the allele frequencies of these four SNPs in the FGF10 gene.We further found that rs12517396AA and rs10462070GG carriers showed a decreased risk of HM/EM compared with rs12517396AC+CC and rs10462070GA+AA carriers(P=0.045,OR=0.366;P=0.021,OR=0.131;P=0.03,OR=0.341;P=0.015,OR=0.122;respectively).Additionally,rs12517396AA and rs10462070GG carriers showed the same decreased risk of HM/EM compared with rs12517396CC and rs10462070AA carriers(P=0.048,OR=0.370;P=0.023,OR=0.133;P=0.032,OR=0.346;P=0.017,OR=0.126).However,these significant associations between rs12517396/rs10462070 and HM/EM disappeared after Bonferroni multiple-correction(P>0.05).Conclusion:Our findings indicate that rs12517396 and rs10462070 had marginal association with HM and EM.The other two common polymorphisms in FGF10 unlikely have significant effects in the genetic predisposition to HM/EM in western Chinese population.Further replication studies are needed to validate our findings in both animal models and human genetic epidemiologic studies. | Lingxi Jiang Dongyan Luo Tingting Wang Rui Zheng Yaru Zhai Xiaoqi Liu Bo Gong Zhengzheng Wu Yin Yang Zhenglin Yang Yi Shi | 2019 | Eye and Vision2019，6，1： | 0 |
| 13 | Characterization of a Novel Esterase Belonging to Family V from Marinobacter flavimaris显示文摘Lipolytic enzymes have attracted enormous attentions because of their ability in ester hydrolysis,ester synthesis,transesterification and other biochemical reactions.Bacteria are important sources of lipolytic enzymes applied in industry.Here,a novel lipolytic enzyme encoded by esterase gene est1347 was identified in Marinobacter flavimaris WLL162,and was purified and characterized.The lipolytic enzyme Est1347 consisted of 312 amino acid residues and a 21-amino-acids N-terminal signal peptide with a predicted molecular weight of 34.2 kDa.It belongs to family V of bacterial lipolytic enzymes based on the amino acid sequence homology analysis.Est1347 is a mesophilic and alkali-resistant enzyme with the highest activity at 45℃and pH 8.5;it is stable at temperatures below 50℃and pH 7.5–11.0.Est1347 showed a preference for middle-length chain substrate p-NPC10 and a wide range of other substrates.The Km,Vmax,Kcat and Kcat/Km values of Est1347 for p-NPC10 in pH 8.5 at 45℃were 0.9411 mmol L^(−1),1285μmol min^(−1)mg^(−1),698.91 s^(−1)and 743.65 s^(−1)(mmol L^(−1))^(−1),respectively.It is also tolerant to the metal ions,organic solvents and detergents.In conclusion,the esterase Est1347 laid a foundation for further study of bacterial lipolytic enzyme family V. | HE Jingjing ZHANG Yunhui WU Leilei WANG Yaru ZHANG He LIU Zhengang SHI Xiaochong | 2024 | Journal of Ocean University of China2024，23，1： | 0 |
| 14 | Contrasting phenology responses to climate warming across the northern extra-tropics显示文摘Climate warming has substantially advanced the timing of spring leaf-out of woody species at middle and high latitudes,albeit with large differences.Insights in the spatial variation of this climate warming response may therefore help to constrain future trends in leaf-out and its impact on energy,water and carbon balances at global scales.In this study,we used in situ phenology observations of 38 species from 2067 study sites,distributed across the northern hemisphere in China,Europe and the United States,to investigate the latitudinal patterns of spring leaf-out and its sensitivity(S T,advance of leaf-out dates per degree of warming)and correlation(R_(T),partial correlation coefficient)to temperature during the period 1980-2016.Across all species and sites,we found that S_(T) decreased significantly by 0.15±0.02 d℃^(-1)°N^(-1),and R_(T) increased by 0.02±0.001°N^(-1)(both at P<0.001).The latitudinal patterns in R_(T) and S_(T) were explained by the differences in requirements of chilling and thermal forcing that evolved to maximize tree fitness under local climate,particularly climate predictability and summed precipitation during the pre-leaf-out season.Our results thus showed complicated spatial differences in leaf-out responses to ongoing climate warming and indicated that spatial differences in the interactions among environmental cues need to be embedded into large-scale phenology models to improve the simulation accuracy. | Xiaojun Geng Yaru Zhang Yongshuo H.Fu Fanghua Hao Ivan A.Janssens Josep Penuelas Shilong Piao Jing Tang Zhaofei Wu Jing Zhang Xuan Zhang Nils Chr.Stenseth | 2022 | Fundamental Research2022，2，5： | 0 |
| 15 | Rational construction and triethylamine sensing performance of foam shapedα-MoO_(3)@SnS_(2) nanosheets显示文摘Owing to their high surface area,stable structure and easy fabrication,composite nanomaterials with encapsulation structures have attracted considerable research interest as sensing materials to detect volatile organic compounds.Herein,a hydrothermal route is designed to prepare foam shapedα-MoO_(3)@SnS_(2)nanosheets that exhibit excellent sensing performance for triethylamine(TEA).The developed sensor,based onα-MoO_(3)@SnS_(2)nanosheets,displays a high response of 114.9 for 100 ppm TEA at a low working temperature of 175℃with sensitivity higher than many other reported sensors.In addition,the device shows a wide concentration detection range(from 500 ppb to 500 ppm),good stability after exposure to air for 80 days,and excellent selectivity.The superior sensing characteristics of the developed sensor are attributed to the high crystallinity ofα-MoO_(3)/SnS_(2),excessive and accessible active sites provided by the good permeability of porous SnS_(2)shells,and the excellent conductivity of the encapsulation heterojunction structure.Thus,the foam shapedα-MoO_(3)@SnS_(2)nanosheets presented herein have promising practical applications in TEA gas sensing devices. | Xianhui Dong Qing Han Yaru Kang Haidong Li Xinyu Huang Zhengtao Fang Huimin Yuan Ahmed A.Elzatahry Zongtao Chi Guanglei Wu Wanfeng Xie | 2022 | Chinese Chemical Letters2022，33，1： | 0 |
| 16 | Highly Aligned Graphene Aerogels for Multifunctional Composites显示文摘Stemming from the unique in-plane honeycomb lattice structure and the sp^(2)hybridized carbon atoms bonded by exceptionally strong carbon–carbon bonds,graphene exhibits remarkable anisotropic electrical,mechanical,and thermal properties.To maximize the utilization of graphene’s in-plane properties,pre-constructed and aligned structures,such as oriented aerogels,films,and fibers,have been designed.The unique combination of aligned structure,high surface area,excellent electrical conductivity,mechanical stability,thermal conductivity,and porous nature of highly aligned graphene aerogels allows for tailored and enhanced performance in specific directions,enabling advancements in diverse fields.This review provides a comprehensive overview of recent advances in highly aligned graphene aerogels and their composites.It highlights the fabrication methods of aligned graphene aerogels and the optimization of alignment which can be estimated both qualitatively and quantitatively.The oriented scaffolds endow graphene aerogels and their composites with anisotropic properties,showing enhanced electrical,mechanical,and thermal properties along the alignment at the sacrifice of the perpendicular direction.This review showcases remarkable properties and applications of aligned graphene aerogels and their composites,such as their suitability for electronics,environmental applications,thermal management,and energy storage.Challenges and potential opportunities are proposed to offer new insights into prospects of this material. | Ying Wu Chao An Yaru Guo Yangyang Zong Naisheng Jiang Qingbin Zheng Zhong‑Zhen Yu | 2024 | Nano-Micro Letters2024，16，6： | 0 |
| 17 | PLZF restricts intestinal ILC3 function in gut defense显示文摘Group 3 innate lymphoid cells(ILC3s)play important roles in maintaining intestinal homeostasis by protecting the host from pathogen infections and tissue inflammation.The transcription factor PLZF(promyelocytic leukemia zinc finger),encoded by zinc finger BTB domain containing 16(Zbtb16),is highly and transiently expressed in ILC precursors(ILCPs).However,the role of PLZF in regulating ILC3 development and function remains unknown.Here,we show that PLZF was specifically expressed in mature intestinal ILC3s compared with other ILC subsets.PLZF was dispensable for ILC3 development.However,PLZF deficiency in ILC3s resulted in increased innate interleukin-22(IL-22)secretion and protection against gut infection and inflammation.Mechanistically,PLZF negatively regulated IL-22 expression by ILC3s in a cell-intrinsic manner by binding to the IL-22 promoter region for transcriptional repression.Together,our data suggest that PLZF restricts intestinal ILC3 function to regulate gut immune homeostasis. | Yaru Xu Huasheng Zhang Shuai Wu Jianyue Liu Hongzhi Liu Dongdi Wang Youqin Zhang Hongshen Niu Xiaohui Su Jiping Sun Lei Shen | 2023 | Cellular & Molecular Immunology2023，20，4： | 0 |
| 18 | Synthesis of symmetrical medium-and long-chain triacylglycerols rich in arachidonic acid at sn-2 position for infant formula显示文摘Medium-and long-chain triacylglycerols(MLCT)rich in arachidonic acid(ARA)at sn-2 position were synthesized by a two-step enzymatic method.Firstly,sn-2 monoacylglycerols(MAG)were synthesized at a temperature of 25℃ by enzymatic alcoholysis.The MAG with 69.42%ARA at sn-2 position were obtained by solvent extraction and low temperature solvent crystallization.Secondly,the MLCT rich in ARA at sn-2 position and capric acid(CA)at sn-1,3 positions were produced by enzymatic esterification.Under the optimal conditions(MAG:CA=1:3(mol/mol),0.05 MPa vacuum,8% Lipozyme RM IM,5 h,25℃),the content of triacylglycerol was up to 93.60%.The triacylglycerol in the form of C10:0-C20:4-C10:0(including isomers)was about 40.43%.The ARA contents in the total and sn-2 fatty acid composition of the final product were 32.35%and 51.12%,respectively.MLCT rich in ARA at sn-2 position were successfully produced and the product has the potential application for functional food and infant formula. | Xuan Jiang Jianhua Huang Yaru Li Ye Wen Shibin Wu Xiuli Xu Zhonghao Chao Hong Zhang Xiaoqiang Zou | 2022 | Food Bioscience2022，45，1： | 0 |
| 19 | A heteropolysaccharide from Rhodiola rosea L.:preparation,purification and anti-tumor activities in H22-bearing mice显示文摘Numerous polysaccharides isolated from plants have been used to augment traditional drugs in the treatment of cancer.In order to explore the influence to hepatocellular carcinoma,a novel cold water-soluble polysaccharide was separated from Rhodiola rosea L.root(RLP)and then its structure and anti-cancer activities were tested.The chemical compositions and high performance gel permeation chromatography(HPGPC)results indicated that RLP was an acid heteropolysaccharide with the molecular weight of about1.15×10~6 Da.Furthermore,ion chromatography(IC),Fourier transform infrared(FT-IR)and nuclear magnetic resoance(NMR)further indicated that RLP was main composed of→2,4)-α-Rha(1→,→5)-α-L-Araf-(1→,α-D-Glu,→6)-β-D-Galp-(1→,β-D-Man and→4)-α-GalpA-(1→.In vivo antitumor activities of RLP were carried out by using H22 tumor-bearing mice model.The results shown that RLP(100 and 300 mg/kg)could inhibit tumor growth of H22 cells from 23.59%to 45.52%and protect thymuses and spleen without damage.In addition,according to cell cycle,AV-FITC/PI and JC-1,RLP could induce dose-dependent apopto sis of H22 cells via S phase arrested which was through a mitochondrial related pathway.Our data indicated that RLP has a broader application prospect in anti-tumor preparations. | Yaru Wu Qing Wang Huiping Liu Lulu Niu Mengyu Li Qi Jia | 2023 | Food Science and Human Wellness2023，12，2： | 0 |
| 20 | Research on Construction Process of EPS in the Thermal Insulation Building显示文摘 | Xiuli Wu Li zhou Yaru Fan | 2015 | International Journal of Technology Management2015，，6： | 0 |
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