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| 1 | Endovascular therapy for Acute ischemic Stroke Trial (EAST): study protocol for a prospective, multicentre control trial in China显示文摘Background and purpose:5 recent trials have shown the benefit of endovascular treatment for acute ischaemic stroke(AIS)due to large vessel occlusion of the anterior circulation.This study aims to evaluate the safety and efficacy of Solitaire thrombectomy in patients with moderate-to-severe stroke in the Chinese population,which has a high prevalence of intracranial atherosclerosis.Methods and analysis:This multicentre prospective control study will involve 17 stroke centres in China,and plans to recruit 150 patients in the intervention group,and 150 patients in the medical group,in which patients meet enrolment criteria but refuse intervention.Patients with AIS due to large vessel occlusion indicated for treatment with Solitaire stent retriever within 12 hours of symptom onset,and who meet the inclusion and exclusion criteria,will be enrolled in this study.The primary efficacy endpoint is functional independence as defined by a modified Rankin Scale(mRS)score≤2 at 90 days or by functional improvement as defined by mRS,using shift analysis.The procedural efficacy endpoint is arterial recanalisation of the occluded target vessel measured by a modified Thrombolysis in Cerebral Infarction(mTICI)score equal or superior to 2b right following the use of the study device.The primary safety endpoint is symptomatic intracranial haemorrhage(sICH)within 24±3 hours postprocedure.Ethics and dissemination:The protocol was approved by the Ethics Committee at the coordinating centre and by the local Institutional Review Board of each participating centre.Trial registration number:NCT02350283. | Zhongrong Miao Xiaochuan Huo Feng Gao Xiaoling Liao Chunjuan Wang Ya Peng Yibin Cao Shengli Chen Meng Zhang Changchun Jiang Xiaoxiang Peng Cunfeng Song Liping Wei Qiyi Zhu Zaiyu Guo Li Liu Hang Lin Hua Yang Wei Wu Hui Liang Anding Xu Kangning Chen Xingquan Zhao Yuesong Pan Hao Li Liping Liu Yilong Wang Yongjun Wang EAST investigators | 2016 | Stroke & Vascular Neurology2016，1，2： | 8 |
| 2 | Engineering three-layer core–shell S-1/TS-1@dendritic-SiO_(2) supported Au catalysts towards improved performance for propene epoxidation with H_(2) and O_(2)显示文摘The advocacy of green chemical industry has led to the development of highly efficient catalysts for direct gas-phase propene epoxidation with green,sustainable and simple essence.The S-1/TS-1@dendritic-SiO_(2) material with three-layer core–shell structure was developed and used as the support for Au catalysts,which showed simultaneously fantastic PO formation rate,PO selectivity and stability(over 100 h)for propene epoxidation with H_(2) and O_(2).It is found that silicalite-1(S-1)core and the middle thin layer of TS-1 offer great mass transfer ability,which could be responsible for the excellent stability.The designed dendritic SiO_(2) shell covers part of the acid sites on the external surface of TS-1,inhibiting the side reactions and improving the PO selectivity.Furthermore,three kinds of SiO_(2) shell morphologies(i.e.,dendritic,net,mesoporous shell)were designed,and relationship between shell morphology and catalytic performance was elucidated.The results in this paper harbour tremendous guiding significance for the design of highly efficient epoxidation catalysts. | Zhaoning Song Juncong Yuan Zhenping Cai Dong Lin Xiang Feng Nan Sheng Yibin Liu Xiaobo Chen Xin Jin De Chen Chaohe Yang | 2020 | Green Energy & Environment2020，5，4： | 3 |
| 3 | Investigation on Organic Solvent Free Toluene Oxidative Bromination Reaction Catalyzed by HTS Zeolite显示文摘The toluene oxidative bromination reaction catalyzed by hollow titanium silicalite(HTS)zeolite in aqueous medium was investigated by employing H2O2 and HBr under mild conditions without the need for organic solvent.A high toluene conversion(90.7%)and high selectivity of mono-bromotoluene(99.0%)was achieved under the optimal reaction conditions.The UV-Raman spectroscopy was applied for the mechanism study and the result reveals that HTS is efficient for catalyzing the oxidation reaction of HBr with H2O2 to produce abundant active bromine species,which can further facilitate the toluene electrophilic bromination reaction.A two-step toluene bromination reaction mechanism involving the HTS catalyzed active bromine species“generation-conversion-utilization”process is proposed based on the UV-Raman spectroscopy analysis. | Peng Xinxin Xia Changjiu Lin Min Zhu Bin Luo Yibin Shu Xingtian | 2020 | China Petroleum Processing & Petrochemical Technology2020，22，4： | 2 |
| 4 | Genomic Variations in the Tea Leafhopper Reveal the Basis of Its Adaptive Evolution显示文摘Tea green leafhopper(TGL),Empoasca onukii,is of biological and economic interest.Despite numerous studies,the mechanisms underlying its adaptation and evolution remain enigmatic.Here,we use previously untapped genome and population genetics approaches to examine how the pest adapted to different environmental variables and thus has expanded geographically.We complete a chromosome-level assembly and annotation of the E.onukii genome,showing notable expansions of gene families associated with adaptation to chemoreception and detoxification.Genomic signals indicating balancing selection highlight metabolic pathways involved in adaptation to a wide range of tea varieties grown across ecologically diverse regions.Patterns of genetic variations among 54 E.onukii samples unveil the population structure and evolutionary history across different tea-growing regions in China.Our results demonstrate that the genomic changes in key pathways,including those linked to metabolism,circadian rhythms,and immune system functions,may underlie the successful spread and adaptation of E.onukii.This work highlights the genetic and molecular basis underlying the evolutionary success of a species with broad economic impacts,and provides insights into insect adaptation to host plants,which will ultimately facilitate more sustainable pest management. | Qian Zhao Longqing Shi Weiyi He Jinyu Li Shijun You Shuai Chen Jing Lin Yibin Wang Liwen Zhang Guang Yang Liette Vasseur Minsheng You | 2022 | Genomics, Proteomics & Bioinformatics2022，20，6： | 1 |
| 5 | A JNK-Dependent Pathway Is Required for TNFα-Induced Apoptosis显示文摘 | Yibin Deng Xiaoyang Ren Lin Yang Yahong Lin Xiangwei Wu | 2003 | Cell2003，，1： | 1 |
| 6 | Morphology and texture evolution of FeCrAlTi–Y 2 O 3 foil fabricated by EBPVD显示文摘 | Xiu Lin Xiaodong He Yue Sun Yibin Li Guangping Song Xinyan Li Jiazhen Zhang | 2010 | Surface & Coatings Technology2010，，1： | 1 |
| 7 | Theory and application of near infrared spectroscopy in assessment of fruit quality: A review显示文摘 | Lin Hongjian Ying Yibin | 2009 | Sensing and Instrumentation for Food Quality and Safety2009，3，2： | 1 |
| 8 | Review of Smart Grid Comprehensive Assessment Systems显示文摘 | Qiang Sun Xubo Ge Lin Liu Xin Xu Yibin Zhang Ruixin Niu Yuan Zeng | 2011 | Energy Procedia2011，，： | 1 |
| 9 | Photocatalytic property of nitrogen-doped layered perovskite K2La2Ti3O10显示文摘 | Yunfang Huang Yuelin Wei Shuhong Cheng Leqing Fan Yibin Li Jianmin Lin Jihuai Wu | 2010 | Solar Energy Materials & Solar Cells2010，94，： | 1 |
| 10 | Enhancing the dynamic electron transfer of Au species on wormhole-like TS-1 for boosting propene epoxidation performance with H_(2) and O_(2)显示文摘Engineering unique electronic structure of catalyst to boost catalytic performance is of prime scientific and industrial importance.Herein,the identification of intrinsic electronic sensitivity for direct propene epoxidation was first achieved over highly stable Au/wormhole-like TS-1 catalyst.Results show that the electron transfer of Au species can be regulated by manipulating the dynamic evolutions and contents of Au valence states,thus resulting in different catalytic performance in 100 h time-on-stream.By DFT calculations,kinetic analysis and multicharacterizations,it is found that the Au^(0) species with higher electronic population can easily transfer more electrons to activate surface O_(2) compared with Au^(1+) and Au^(3+) species.Moreover,there is a positive correlation between Au^(0) content and activity.Based on this correlation,a facile strategy is further proposed to boost Au^(0) percentage,resulting in the reported highest PO formation rate without adding promoters.This work harbors tremendous guiding significance to the design of highly efficient Au/Ti-containing catalyst for propene epoxidation with H_(2) and O_(2). | Dong Lin Xiuhui Zheng Xiang Feng Nan Sheng Zhaoning Song Yibin Liu Xiaobo Chen Zhenping Cai De Chen Chaohe Yang | 2020 | Green Energy & Environment2020，5，4： | 1 |
| 11 | FGF8-mediated signaling regulates tooth developmental pace during odontogenesis显示文摘The developing human and mouse teeth constitute an ideal model system to study the regulatory mechanism underlying organ growth control since their teeth share highly conserved and well-characterized developmental processes, and their developmental tempo varies notably. In the current study, we manipulated heterogenous recombination between human and mouse dental tissues and demonstrated that the dental mesenchyme dominates the tooth developmental tempo and FGF8 could be a critical player during this developmental process. Forced activation of FGF8 signaling in the dental mesenchyme of mice promoted cell proliferation, prevented cell apoptosis via p38 and perhaps PI3 K-Akt intracellular signaling,and impelled the transition of the cell cycle from G1-to S-phase in the tooth germ, resulting in the slowdown of the tooth developmental pace. Our results provide compelling evidence that extrinsic signals can profoundly affect tooth developmental tempo, and the dental mesenchymal FGF8 could be a pivotal factor in controlling the developmental pace in a non-cell-autonomous manner during mammalian odontogenesis. | Chensheng Lin Ningsheng Ruan Linjun Li Yibin Chen Xiaoxiao Hu YiPing Chen Xuefeng Hu Yanding Zhang | 2022 | Journal of Genetics and Genomics2022，49，1： | 1 |
| 12 | Insights into the Reaction Network and Mechanism of Green Aerobic Oxidative Esterification of Methacrolein over Different Heterogeneous Catalysts显示文摘The oxidative esterification of methacrolein(MAL)is an important way to prepare high-valued methyl methacrylate(MMA),but this process is ultra-complex due to the high reactivity of both C=O and C=C bonds in MAL molecule.In order to further improve MMA selectivity,the reaction network and relevant mechanisms have been proposed and profoundly investigated in this paper.Five kinds of fundamental reactions are involved in this process,including(a)the acetal reaction;(b)the aerobic oxidation of hemiacetal;(c)the alkoxylation of C=C double bond;(d)the Diels-Alder reaction;and(e)the hydrogenation reaction of unsaturated double bond.Among them,the Diels-Alder reaction of MAL is non-catalyzed,and the Brönsted acid sites or the Lewis acid sites favor promoting acetal reaction of MAL with methanol,while the alkoxylation of C=C bond with methanol is enhanced under alkaline condition.In particular,by employing the Pd-based catalysts,hydrogenation products are formed in alkaline methanol solution,hence with lower than those obtained by the Au-based catalysts.Notably,it is necessary to match the hemiacetal fromation and aerobic oxidation of hemiacetal,which is relevant with the amount and strength of acid and redox sites.Consequently,this work can provide a good guidance for the further design of both catalysts and processes in future. | Li Chenhao Xia Changjiu Liu Yujia Huang Kaimeng Peng Xinxin Liu Jinsheng Lin Min Zhu Bin Luo Yibin Shu Xingtian | 2021 | China Petroleum Processing & Petrochemical Technology2021，23，3： | 1 |
| 13 | Catalyst for Increasing Ethylene and Propylene Production and Its Industrial Application in a Catalytic Pyrolysis Unit显示文摘Light olefins,particularly ethylene and propylene,are the most important building blocks for the petrochemical industry,and demand for their production has been increasing.The catalytic pyrolysis process(CPP)and the corresponding catalyst,developed by SINOPEC Research Institute of Petroleum Processing Co.,Ltd.,are designed to maximize the light olefin yield from catalytic cracking of heavy feedstocks.However,owing to the continuing degradation of feedstocks,the original catalyst can no longer maintain its activity.Herein,we describe the rational design of the new catalyst,Epylene,from a new metal-modified hierarchical ZSM-5 zeolite and matrix.Epylene was tested in the CPP unit of Shaanxi Yanchang Coal Yulin Energy and Chemical Company.A test run and base run were conducted to demonstrate the better performance of Epylene compared with the original catalyst.The properties of the feedstocks and the operating conditions in both runs were similar.The light olefin yield was increased from 33.95%to 36.50%and the coke yield was only 9.58%in the test run,which was lower than that in the base run. | Sha Yuchen Wang Peng Ouyang Ying Zhu Genquan Lu Lijun Song Haitao Lin Wei Luo Yibin | 2023 | China Petroleum Processing & Petrochemical Technology2023，25，2： | 1 |
| 14 | Bisulfite-free mapping of DNA cytosine modifications:challenges and perspectives显示文摘The mapping of DNA cytosine modifications is crucial for understanding the dynamic landscape of epigenetic regulation.While bisulfite sequencing has been the gold standard for decades,it suffers from limitations such as DNA degradation and low library quality due to harsh chemical treatment.In recent years,bisulfite-free methods have emerged as promising alternatives for detecting and quantifying DNA cytosine modifications.These methods employ enzymatic and chemical strategies to investigate cytosine modifications without the need for bisulfite treatment.This review provides an overview of the historical context of bisulfite-based methods and presents the current landscape of bisulfite-free methods.The advantages and limitations of each approach are discussed,along with insights into their applications.Furthermore,the review explores the existing challenges in the field and presents future perspectives and potential directions for advancing bisulfite-free mapping methods.The continued progress in bisulfite-free techniques holds great promise for unraveling the intricate nature of DNA cytosine modifications and their functional implications in diverse biological processes and diseases. | Yanfang Du Ying Tang Bingqian Lin Xiaochen Xue Yafen Wang Yibin Liu | 2023 | Science China Chemistry2023，66，11： | 0 |
| 15 | Kinetic Investigation of a Cucurbit[7]uril-Based Pseudo[6]rotaxane System by Microfluidic Nuclear Magnetic Resonance显示文摘It is challenging to investigate fast supramolecular processes due to the lack of appropriate characterization methods with high structural resolution.In this study,microfluidic nuclear magnetic resonance(μFNMR)spectroscopy was employed to monitor the kinetics of threading and dethreading of a pseudo[6]rotaxane system.By employing high time resolutionμF-NMR,1 H and two-dimensional(2D)rotating frame nuclear Overhauser effect spectroscopy(ROESY)NMR spectra were recorded at any time point within 1.5 s after the onset of the process.This technique enabled the successful identification of kinetic intermediates and rate-determining steps,usually impossible to determine by other spectroscopic techniques.Thus,our study demonstrates the capability ofμF-NMR in investigating the mechanism of complex supramolecular systems. | Yibin Sun Hongxun Fang Xujing Lin Xiuxiu Wang Ganyu Chen Xinchang Wang Zhongqun Tian Liulin Yang Marcel Utz Xiaoyu Cao | 2022 | CCS Chemistry2022，4，2： | 0 |
| 16 | Speech Enhancement via Mask-Mapping Based Residual Dense Network显示文摘Masking-based and spectrum mapping-based methods are the two main algorithms of speech enhancement with deep neural network(DNN).But the mapping-based methods only utilizes the phase of noisy speech,which limits the upper bound of speech enhancement performance.Maskingbased methods need to accurately estimate the masking which is still the key problem.Combining the advantages of above two types of methods,this paper proposes the speech enhancement algorithm MM-RDN(maskingmapping residual dense network)based on masking-mapping(MM)and residual dense network(RDN).Using the logarithmic power spectrogram(LPS)of consecutive frames,MM estimates the ideal ratio masking(IRM)matrix of consecutive frames.RDN can make full use of feature maps of all layers.Meanwhile,using the global residual learning to combine the shallow features and deep features,RDN obtains the global dense features from the LPS,thereby improves estimated accuracy of the IRM matrix.Simulations show that the proposed method achieves attractive speech enhancement performance in various acoustic environments.Specifically,in the untrained acoustic test with limited priors,e.g.,unmatched signal-to-noise ratio(SNR)and unmatched noise category,MM-RDN can still outperform the existing convolutional recurrent network(CRN)method in themeasures of perceptual evaluation of speech quality(PESQ)and other evaluation indexes.It indicates that the proposed algorithm is more generalized in untrained conditions. | Lin Zhou Xijin Chen Chaoyan Wu Qiuyue Zhong Xu Cheng Yibin Tang | 2023 | Computers, Materials & Continua2023，，1： | 0 |
| 17 | NEW STORIES IN BEIJING'S CULTURAL PARKS显示文摘There are many approaches to assessing the cultural development of a city.The construction and development of cultural and creative industry parks can serve as one barometer for measuring cultural development.During the China International Fair for Trade in Services 2021 from September 2 to 7 in Beijing,10 cultural and creative industry parks,including Zhongguancun Software Park,768 Creative Industry Park and Jiacheng Hutong Creative Workshop,along with 80 companies located in the parks,were present to display the latest developments in the capital city. | Zhang Hongpeng(Translated) Brad Green Jin Jianhui(Photos) Wu Yibin(Photos) | 2021 | Beijing2021，，38： | 0 |
| 18 | Binaural Speech Separation Algorithm Based on Long and Short Time Memory Networks显示文摘Speaker separation in complex acoustic environment is one of challenging tasks in speech separation.In practice,speakers are very often unmoving or moving slowly in normal communication.In this case,the spatial features among the consecutive speech frames become highly correlated such that it is helpful for speaker separation by providing additional spatial information.To fully exploit this information,we design a separation system on Recurrent Neural Network(RNN)with long short-term memory(LSTM)which effectively learns the temporal dynamics of spatial features.In detail,a LSTM-based speaker separation algorithm is proposed to extract the spatial features in each time-frequency(TF)unit and form the corresponding feature vector.Then,we treat speaker separation as a supervised learning problem,where a modified ideal ratio mask(IRM)is defined as the training function during LSTM learning.Simulations show that the proposed system achieves attractive separation performance in noisy and reverberant environments.Specifically,during the untrained acoustic test with limited priors,e.g.,unmatched signal to noise ratio(SNR)and reverberation,the proposed LSTM based algorithm can still outperforms the existing DNN based method in the measures of PESQ and STOI.It indicates our method is more robust in untrained conditions. | Lin Zhou Siyuan Lu Qiuyue Zhong Ying Chen Yibin Tang Yan Zhou | 2020 | Computers, Materials & Continua2020，，6： | 0 |
| 19 | Composition,function,and timing:exploring the early‑life gut microbiota in piglets for probiotic interventions显示文摘Background The establishment of a robust gut microbiota in piglets during their early developmental stage holds the potential for long-term advantageous effects.However,the optimal timeframe for introducing probiotics to achieve this outcome remains uncertain.Results In the context of this investigation,we conducted a longitudinal assessment of the fecal microbiota of 63 piglets at three distinct pre-weaning time points.Simultaneously,we gathered vaginal and fecal samples from 23 sows.Employing 16S rRNA gene and metagenomic sequencing methodologies,we conducted a comprehensive analysis of the fluctuation patterns in microbial composition,functional capacity,interaction networks,and colonization resistance within the gut microbiota of piglets.As the piglets progressed in age,discernible modifications in intestinal microbial diversity,composition,and function were observed.A source-tracking analysis unveiled the pivotal role of fecal and vaginal microbiota derived from sows in populating the gut microbiota of neonatal piglets.By D21,the microbial interaction network displayed a more concise and efficient configuration,accompanied by enhanced colonization resistance relative to the other two time points.Moreover,we identified three strains of Ruminococcus sp.at D10 as potential candidates for improving piglets’weight gain during the weaning phase.Conclusions The findings of this study propose that D10 represents the most opportune juncture for the introduction of external probiotic interventions during the early stages of piglet development.This investigation augments our comprehension of the microbiota dynamics in early-life of piglets and offers valuable insights for guiding forthcoming probiotic interventions. | Jianping Quan Cineng Xu Donglin Ruan Yong Ye Yibin Qiu Jie Wu Shenping Zhou Menghao Luan Xiang Zhao Yue Chen Danyang Lin Ying Sun Jifei Yang Enqin Zheng Gengyuan Cai Zhenfang Wu Jie Yang | 2024 | Journal of Animal Science and Biotechnology2024，15，2： | 0 |
| 20 | Self-powered flexible fingerprint-recognition display based on a triboelectric nanogenerator显示文摘In the time of Internet of Things(IoT),alternating current electroluminescence(ACEL)has unique advantages in the fields of smart display and human–computer interaction.However,their reliance on external high-voltage AC power supplies poses challenges in terms of wearability and limits their practical application.This paper proposed an innovative scheme for preparing a feather triboelectric nanogenerator(F-TENG)using recyclable and environmentally friendly material.The highest open-circuit voltage,short-circuit current,and transferred charge of SF6-treated F-TENGs can reach 449 V,63μA,and 152 nC,which enables easy lighting of BaTiO_(3)^(-)doped ACEL devices.Using a human electrical potential,a single-electrode F-TENG is combined with ACEL device for self-powered fingerprint recognition display.These works achieve self-powered flexible wearable ACEL devices,which are not only efficient and portable but also have good application prospects in the human–computer interaction,functional displays,and wearable electronic devices. | Wandi Chen Haonan Wang Yibin Lin Xinyan Gan Heng Tang Yongai Zhang Qun Yan Tailiang Guo Xiongtu Zhou Chaoxing Wu | 2024 | Nano Research2024，17，4： | 0 |
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