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| 1 | Artificial Intelligence Applications in the Development of Autonomous Vehicles:A Survey显示文摘The advancement of artificial intelligence(AI)has truly stimulated the development and deployment of autonomous vehicles(AVs)in the transportation industry.Fueled by big data from various sensing devices and advanced computing resources,AI has become an essential component of AVs for perceiving the surrounding environment and making appropriate decision in motion.To achieve goal of full automation(i.e.,self-driving),it is important to know how AI works in AV systems.Existing research have made great efforts in investigating different aspects of applying AI in AV development.However,few studies have offered the research community a thorough examination of current practices in implementing AI in AVs.Thus,this paper aims to shorten the gap by providing a comprehensive survey of key studies in this research avenue.Specifically,it intends to analyze their use of AIs in supporting the primary applications in AVs:1)perception;2)localization and mapping;and 3)decision making.It investigates the current practices to understand how AI can be used and what are the challenges and issues associated with their implementation.Based on the exploration of current practices and technology advances,this paper further provides insights into potential opportunities regarding the use of AI in conjunction with other emerging technologies:1)high definition maps,big data,and high performance computing;2)augmented reality(AR)/virtual reality(VR)enhanced simulation platform;and 3)5G communication for connected AVs.This paper is expected to offer a quick reference for researchers interested in understanding the use of AI in AV research. | Yifang Ma Zhenyu Wang Hong Yang Lin Yang | 2020 | IEEE/CAA Journal of Automatica Sinica2020，7，2： | 16 |
| 2 | A two-step lineage reprogramming strategy to generate functionally competent human hepatocytes from fibroblasts显示文摘Terminally differentiated cells can be generated by lineage reprogramming,which is,however,hindered by incomplete conversion with residual initial cell identity and partial functionality. Here, we demonstrate a new reprogramming strategy by mimicking the natural regeneration route, which permits generating expandable hepatic progenitor cells and functionally competent human hepatocytes. Fibroblasts were first induced into human hepatic progenitor-like cells (hHPLCs), which could robustly expand in vitro and efficiently engraft in vivo. Moreover, hHPLCs could be efficiently induced into mature human hepatocytes (hiHeps) in vitro, whose molecular identity highly resembles primary human hepatocytes (PHHs). Most importantly, hiHeps could be generated in large quantity and were functionally competent to replace PHHs for drug-metabolism estimation, toxicity prediction and hepatitis B virus infection modeling. Our results highlight the advantages of the progenitor stage for successful lineage reprogramming. This strategy is promising for generating other mature human cell types by lineage reprogramming. | Bingqing Xie Da Sun Yuanyuan Du Jun Jia Shicheng Sun Jun Xu Yifang Liu Chengang Xiang Sitong Chen Huangfan Xie Qiming Wang Guangya Li Xuehui LYU Hui Shen Shiyu Li Min Wu Xiaonan Zhang Yue Pu Kuanhui Xiang Weifeng Lai Peng Du Zhenghong Yuan Cheng Li Yan Shi Shichun Lu Hongkui Deng | 2019 | Cell Research2019，29，9： | 9 |
| 3 | Variation in cis-regulation of a NAC transcription factor contributes to drought tolerance in wheat显示文摘Drought is a major environmental factor limiting wheat production worldwide,and developing drought-tolerant cultivars is a central challenge for wheat breeders globally.Therefore,it is important to identify genetic components determining drought tolerance in wheat.In this study,we identified a wheat NAC gene(TaNAC071-A)that is tightly associated with drought tolerance by a genome-wide association study.Knockdown of TaNAC071-A in wheat attenuated plant drought tolerance,whereas its overexpression significantly enhanced drought tolerance through improved water-use efficiency and increased expression of stress-responsive genes.This heightened water-saving mechanism mitigated the yield loss caused by water deficit.Further candidate gene association analysis showed that a 108-bp insertion in the promoter of TaNAC071-A alters its expression level and contributes to variation in drought tolerance among wheat accessions.This insertion contains two MYB cis-regulatory elements(CREs)that can be directly bound by the MYB transcription activator,TaMYBL1,thereby leading to increased TaNAC071-A expression and plant drought tolerance.Importantly,introgression of this 108-bp insertion allele,TaNAC071-AIn-693,into drought-sensitive cultivars could improve their drought tolerance,demonstrating that it is a valuable genetic resource for wheat breeding.Taken together,our findings highlight a major breakthrough in determining the genetic basis underlying phenotypic variation in wheat drought tolerance and showcase the potential of exploiting CRE-containing indels for improving important agronomical traits. | Hude Mao Shumin Li Bin Chen Chao Jian Fangming Mei Yifang Zhang Fangfang Li Nan Chen Tian Li Linying Du Li Ding Zhongxue Wang Xinxiu Cheng Xiaojing Wang Zhensheng Kang | 2022 | Molecular Plant2022，15，2： | 9 |
| 4 | INTEGRATED APPROACH TO ASSEMBLY SEQUENCE PLANNING OF C0MPLEX PRODUCTS显示文摘Assembly sequence planning will be more difficult due to the in-creasing complexity of products.An integrated approach to assembly sequence planning of complex products applying de-composition-planning-combination strategy is presented.First,an assembly is decomposed into a hierarchical structure using an assembly structure representation based on connectors.Then,an assembly planning system is used to generate the sequences that are locally optimal for each leaf partition in the structure hierarchy.By combining the local sequences systematically in a bottom-up manner and choosing suitable ones from the merged sequences,the assembly sequence of each parent structure including the whole assembly is generated.An integrated system has been completed.A complex product is given to illustrate the feasibility and the practicality of the approach. | Wang Junfeng Liu Jihong Zhong Yifang CAD Center,Huazhong University of Science and Technology,Wuhan 430074, China | 2004 | Chinese Journal of Mechanical Engineering2004，17，2： | 8 |
| 5 | Pathological changes in the lungs and lymphatic organs of 12 COVID-19 autopsy cases显示文摘Systematic autopsy and comprehensive pathological analyses of COVID-19 decedents should provide insights into the disease characteristics and facilitate the development of novel therapeutics.In this study,we report the autopsy findings from the lungs and lymphatic organs of 12 COVID-19 decedents—findings that evaluated histopathological changes;immune cell signature and inflammatory factor expression in the lungs,spleen and lymph nodes.Here we show that the major pulmonary alterations included diffuse alveolar damage,interstitial fibrosis and exudative inflammation featured with extensive serous and fibrin exudates,macrophage infiltration and abundant production of inflammatory factors(IL-6,IP-10,TNFo?and IL-I f).The spleen and hilar lymph nodes contained lesions with tissue structure disruption and immune cell dysregulation,including lymphopenia and macrophage accumulation.These findings provide pathological evidence that links injuries of the lungs and lymphatic organs with the fatal systematic respiratory and immune malfunction in critically ill COVID-19 patients. | Qian Liu Yu Shi Jun Cai Yaqi Duan Rongshuai Wang Hongyan Zhang Qiurong Ruan Jiansha Li Lei Zhao Yifang Ping Rong Chen Liang Ren Xiaochun Fei Heng Zhang Rui Tang Xi Wang Tao Luo Xindong Liu Xuequan Huang Zhenhua Liu Qilin Ao Yong Ren Jing Xiong Zhicheng He Haibo Wu Wenjuan Fu Pengnan Zhao Xinwei Chen Guoqiang Qu Yunyun Wang Xi Wang Jia Liu Dongfang Xiang Sanpeng Xu Xiaowei Zhou Qingrui Li Jinghong Ma Heng Li Jie Zhang Sizhe Huang Xiaohong Yao Yiwu Zhou Chaofu Wang Dingyu Zhang Guoping Wang Liang Liu Xiu-Wu Bian | 2020 | National Science Review2020，7，12： | 6 |
| 6 | DELAUNAY TRIANGULATION METHOD OF CURVED SURFACES BASED ON RIEMANNIAN METRIC显示文摘A method for quality mesh generation of parametric curved surfaces is proposed. It is shown that the main difference between the proposed method and previous ones is that our meshing process is done completely in the parametric domains with the guarantee of mesh quality. To obtain this aim, the Delaunay method is extended to anisotropic context of 2D domains, and a Riemannian metric map is introduced to remedy the mapping distortion from object space to parametric domain. Compared with previous algorithms, the approach is much simpler, more robust and speedy. The algorithm is implemented and examples for several geometries are presented to demonstrate the efficiency and validity of the method. | Zhao Jianjun Wang QifuZhong Yifang Zhou Ji ZhaoYiCAD Center,Huazhong University of Scienceand Technology,Wuhan 430074, China | 2003 | Chinese Journal of Mechanical Engineering2003，16，1： | 4 |
| 7 | Thermo-optic all-optical devices based on two-dimensional materials显示文摘In this paper, we review our recent work on thermo-optic all-optical devices based on two-dimensional(2 D)materials. The unique properties of 2 D materials enable fast and highly efficient thermo-optic control of light.A few all-optical devices are demonstrated based on various thermo-optic mechanisms. Both fiber and integrated devices will be shown. | KAN WU YIFANG WANG CIYUAN QIU JIANPING CHEN | 2018 | Photonics Research2018，6，10： | 4 |
| 8 | High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors显示文摘A new coronavirus(SARS-CoV-2)has been identified as the etiologic agent for the COVID-19 outbreak.Currently,effective treatment options remain very limited for this disease;therefore,there is an urgent need to identify new anti-COVID-19 agents.In this study,we screened over 6,000 compounds that included approved drugs,drug candidates in clinical trials,and pharmacologically active compounds to identify leads that target the SARS-CoV-2 papain-like protease(PLpro).Together with main protease(Mpro),PLpro is responsible for processing the viral replicase polyprotein into functional units.There-fore,it is an attractive target for antiviral drug develop-ment.Here we discovered four compounds,YM155,cryptotanshinone,tanshinone I and GRL0617 that inhibit SARS-CoV-2 PLpro with IC50 values ranging from 1.39 to 5.63 pmol/L.These compounds also exhibit strong antiviral activities in cell-based assays.YM155,an anti-cancer drug candidate in clinical trials,has the most potent antiviral activity with an EC50 value of 170 nmol/L.In addition,we have determined the crystal structures of this enzyme and its complex with YM155,revealing a unique binding mode.YM155 simultaneously targets three'hot'spots on PLpro,including the substrate-binding pocket,the interferon stimulating gene product 15(ISG15)binding site and zinc finger motif.Our results demonstrate the efficacy of this screening and repur-posing strategy,which has led to the discovery of new drug leads with clinical potential for COVID-19 treatments. | Yao Zhao Xiaoyu Du Yinkai Duan Xiaoyan Pan Yifang Sun Tian You Lin Han Zhenming Jin Weijuan Shang Jing Yu Hangtian Guo Qianying Liu Yan Wu Chao Peng Jun Wang Chenghao Zhu Xiuna Yang Kailin Yang Ying Lei Luke W.Guddat Wenqing Xu Gengfu Xiao Lei Sun Leike Zhang Zihe Rao Haitao Yang | 2021 | Protein & Cell2021，12，11： | 4 |
| 9 | Simulated annealing spectral clustering algorithm for image segmentation显示文摘The similarity measure is crucial to the performance of spectral clustering. The Gaussian kernel function based on the Euclidean distance is usually adopted as the similarity measure. However, the Euclidean distance measure cannot fully reveal the complex distribution data, and the result of spectral clustering is very sensitive to the scaling parameter. To solve these problems,a new manifold distance measure and a novel simulated annealing spectral clustering(SASC) algorithm based on the manifold distance measure are proposed. The simulated annealing based on genetic algorithm(SAGA), characterized by its rapid convergence to the global optimum, is used to cluster the sample points in the spectral mapping space. The proposed algorithm can not only reflect local and global consistency better, but also reduce the sensitivity of spectral clustering to the kernel parameter, which improves the algorithm's clustering performance. To efficiently apply the algorithm to image segmentation, the Nystr¨om method is used to reduce the computation complexity. Experimental results show that compared with traditional clustering algorithms and those popular spectral clustering algorithms, the proposed algorithm can achieve better clustering performances on several synthetic datasets, texture images and real images. | Yifang Yang Yuping Wang | 2014 | Journal of Systems Engineering and Electronics2014，25，3： | 3 |
| 10 | Exploring the design space of immersive urban analytics显示文摘Recent years have witnessed the rapid development and wide adoption of immersive head-mounted devices,such as HTC VIVE,Oculus Rift,and Microsoft HoloLens.These immersive devices have the potential to significantly extend the methodology of urban visual analytics by providing critical 3D context information and creating a sense of presence.In this paper,we propose a theoretical model to characterize the visualizations in immersive urban analytics.Furthermore,based on our comprehensive and concise model,we contribute a typology of combination methods of 2D and 3D visualizations that distinguishes between linked views,embedded views,and mixed views.We also propose a supporting guideline to assist users in selecting a proper view under certain circumstances by considering visual geometry and spatial distribution of the 2D and 3D visualizations.Finally,based on existing work,possible future research opportunities are explored and discussed. | Zhutian Chen Yifang Wang Tianchen Sun Xiang Gao Wei Chen Zhigeng Pan Huamin Qu Yingcai Wu | 2017 | Visual Informatics2017，1，2： | 3 |
| 11 | Evaluating the Role of International Trade in the Growth of China's CO_2 Emissions显示文摘International trade matters in assessing the extent of China’s responsibility for CO2 emissions.A determining factor is whether emissions are measured in production or in consumption terms.Based on a series of input-output tables,an empirical analysis is conducted to measure the impact of international trade on China’s emissions growth during the period 1997 to 2007.The authors also measure the impact on emissions of bilateral trade between China and US,European Union and Japan.As the largest of the developing countries,China has a trade surplus that can substantially influence its measured responsibility for emissions.The authors consider some policy implications for international negotiations to reduce global greenhouse gas emissions. | JIANG Xuemei LIU Yifang ZHANG Jin ZU Lei WANG Shouyang GREEN Christopher | 2015 | Journal of Systems Science & Complexity2015，28，4： | 3 |
| 12 | Antisense Oligodeoxynucleotide Inhibits Expression of Re-com binantPorcine Follicle-Stim ulating Horm one Receptor显示文摘To assess the role of follicle stimulating hormone receptor(FSHR) gene expression in regulating expression of FSHR protein in the plasma membrane, the effects of a porcine FSHR cDNA antisense oligodeoxynucleotide (ODN) on FSHR mRNA levels and 125 I FSH binding were determined in Chinese hamster ovary cells expression recombinant porcine FSHR (pFSHR CHO cells). An 18 mer phosphorothioate endcapped antisense ODN that corresponded to the region surrounding the translation initiation codon of the porcine FSHR cDNA was synthesized. An 18 mer nonsense sequence of identical nucleotide composition, which had little homology to known DNA sequences, was synthesized for use as a control. pFSHR CHO cells were cultured in 24 well plates (10 5 cells/well) in the absence or presence of 1 20 μmol/L antisense or nonsense ODN for 24 h and then assayed for porcine FSHR mRNA, using quantitative reverse transcription and competitive polymerase chain reaction, and for 125 I FSH binding activity. Treatment with 10 μmol/L antisense ODN caused a paradoxical increase in porcine FSHR mRNA from 0.89±0.06 to 1.64±0.08 ng/mg total RNA ( P <0.05). Transfection with lipofectamine and 0.33 μmol/L antisense ODN caused an increase in porcine mRNA from 0.95±0.08 to 1.53±0.07 ng/mg total RAN. This was probably due to upregulation of mRNA synthesis resulting from inhibition of porcine FSHR protein translation. The nonsense ODN had no effect on porcine FSHR mRNA. Antisense, but not nonsense, ODN (10 μmol/L) inhibited membrane binding of 125 I FSH by 13.6± 0.8 % ( P <0.05) in 24 h. Treatment of cells with antisense ODN (10 μmol/L) for 48 h resulted in a 76±1.5 % ( P <0.05) inhibition of 125 I FSH binding. In contrast, transfection with lipofectamine and 0.33 μmol/L antisense ODN at 0 h caused a 76.1±1.3 % ( P <0.05) reduction in binding within 24 h. Binding had returned to 52.3±2.3 % ( P < 0.05) of normal by 48 h. These results indicate that an antisense ODN corresponding to the region of the translation start site of the porcine FSHR cDNA is an effective specific inhibitor of porcine FSHR synthesis and that inhibition of receptor synthesis causes a decrease in functional membrane bound FSHR. | ZHU Changhong 1, Mark D. Nixon 2, WANG Yifang 1, Andrew R. LaBarbera 3 1 Center of Reproductive Medicine, Tongji Hospital, Tongji Medical University, Wuhan 430030 2 Department of Obstetrics and Gynecology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0526 3 Department of Molecular and Cellular Physiology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0526 | 1999 | Journal of Huazhong University of Science and Technology(Medical Sciences)1999，19，3： | 2 |
| 13 | Phase Boundary Mapping in ZrNiSn Half-Heusler for Enhanced Thermoelectric Performance显示文摘The solubility range of interstitial Ni in the ZrNi1+xSn half-Heusler phase is a controversial issue,but it has an impact on the thermoelectric properties.In this study,two isothermal section phase diagrams of the Zr-Ni-Sn ternary system at 973K and 1173 K were experimentally constructed based on the binary phase diagrams of Zr-Ni,Zr-Sn,and Ni-Sn.The thermodynamic equilibrium phases were obtained after a long time of heating treatment on the raw alloys prepared by levitation melting.Solubilities of x<0:07 at 973 K and x<0:13 at 1173 K were clearly indicated.An intermediate-Heusler phase with a partly filled Ni void was observed,which is believed to be beneficial to the lowered lattice thermal conductivity.The highest ZT value~0:71 at 973 K was obtained for ZrNi_(1.11)Sn_(1.04).The phase boundary mapping provides an important instruction for the further optimization of ZrNiSn-based materials and other systems. | Xiaofang Li Pengbo Yang Yumei Wang Zongwei Zhang Dandan Qin Wenhua Xue Chen Chen Yifang Huang Xiaodong Xie Xinyu Wang Mujin Yang Cuiping Wang Feng Cao Jiehe Sui Xingjun Liu Qian Zhang | 2020 | Research2020，，1： | 2 |
| 14 | Stereotactic surgery for refractory epilepsy complicated by mental disorders A retrospective case analysis显示文摘BACKGROUND: Anti-epilepsy and anti-psychosis drugs have traditionally been used in the clinic to treat epilepsy complicated by mental disorders. However, there is still no effective therapy for refractory epilepsy patients suffering from persistent mental disorders. OBJECTIVE: To explore the therapeutic effects of stereotactic multi-element localization and multi-target radiofrequency ablation on patients with refractory primary epilepsy and mental disorders. DESIGN: A retrospective case analysis. SETTING: Department of Neurosurgery, the 454 Hospital of Chinese PLA. PARTICIPANTS: Between June and November 2004, 13 patients with refractory primary epilepsy compli-cated by persistent mental disorders were admitted to the Department of Neurosurgery, the 454 Hospital of Chinese PLA. The patient group consisted of nine males and four females, with an average age of 25 years (range 18-39 years), and a course of disease ranging 3-11 years. Diagnosis of mental disorders was in ac-cordance with Chinese Classification of Mental Disorders. Written informed consent was obtained from all patients and their families, and the treatment protocol was approved by the Ethics Committee of the Hospital. METHODS: Under venous inhalation anesthesia, the disease targets, including bilateral corpus callosum, bilateral amygdala, and bilateral medial septal area, as well as unilateral Forel-H area, were coagulated by RFG-3CF radiofrequency thermocoagulation at 75-80 ℃ for 60-70 seconds. During thermocoagulation, the targets were identified using deep-brain microelectrodes and localized according to electrophysiology and electric resistance values. MAIN OUTCOME MEASURES: One year post-surgery, epileptic seizures were assessed on the basis of the Tan classification, and psychogenic (non-epileptic) seizures were evaluated using a 5-grade system. RESULTS: All enrolled 13 epileptic patients were included in the final analysis. The results of follow-up evaluations demonstrated that epilepsy was well-controlled. In total, nine patients did not experience relapse, and the frequency of seizures was reduced by 75% in two patients, and 50%-74% in another two patients. Psychogenic seizures were ameliorated in 11 cases (class 1, recovery) and improved significantly in two cases (class 2, significant improvement). CONCLUSION: Radiofrequency ablation of bilateral corpus callosum, bilateral amygdala, bilateral medial septal area, and unilateral Forel-H area exhibits certain efficacy in treating epileptic patients suffering from persistent mental disorders. | Yifang Wang Aigang Xu Qifu Tan Zhengwei Wang Dongsheng Jiao Hao Zhu KaidongLiu | 2008 | Neural Regeneration Research2008，3，6： | 2 |
| 15 | Involvement of a cytoplasmic glyceraldehyde-3-phosphate dehydrogenase GapC-2 in low-phosphate-induced anthocyanin accumulation in Arabidopsis显示文摘Phosphorous is one of the essential mineral elements for plant growth and development.Typically, the shoots of plant seedlings usually turn a dark-brown or purple colour under low-Pi stress. Using protein 2-D gel and peptide mass fingerprinting mapping (PMF) methods, a cytoplasmic glyceralde-hyde-3-phosphate dehydrogenase GapC-2 was identified as a low-Pi responsive protein in Arabidopsisplants. Expression of AtGapC-2 protein was significantly decreased after 4 d of low-Pi stress. Two in-dependent T-DNA insertion lines of GapC-2 gene (At1g13440) showed a hypersensitive phenotype inresponse to low-Pi stress compared with wild type plants, while the transgenic complementation linesof the mutants showed a similar phenotype to the wild type. These results indicate that AtGapC-2 mayplay an important role in Arabidopsis responses to low-Pi stress, possibly by regulation of glycoly-sis-associated 'Pi-pool' and accumulation of anthocyanin pigments in plants. | WANG XiYao CHEN YiFang ZOU JunJie WU WeiHua | 2007 | Chinese Science Bulletin2007，52，13： | 2 |
| 16 | The Effect of Corporate Governance on Debt Financing Cost of Listed Companies显示文摘In recent years,bank credit business is booming with the increasing borrowing intention of China’s listed companies,and debt financing has become the major approach among listed companies’financing strategies.As a series of institutional arrangements about rights,responsibilities and benefits between different shareholders,corporate governance mechanism has a significant influence on the cost of debt financing.This paper employs variable coefficient panel data model to investigate the relationship of the listed company’s debt financing costs and corporate governance mechanism in terms of structural characteristics and time series characteristics.The results show that optimizing the structure of both Board of Directors and Board of Supervisors,establishing a reasonable management incentive system and reducing the concentration of ownership properly can directly contribute to a lower company’s debt financing costs.Meanwhile,property rights have an interactive influence on corporate governance from four aspects,which indirectly effect in company’s debt financing costs. | LI Lin DONG Fangyu LIU Yifang HUANG Haijun WANG Shouyang | 2016 | Journal of Systems Science & Complexity2016，29，3： | 2 |
| 17 | Targeting lactate dehydrogenase A (LDHA) exerts antileukemic effects on T-cell acute lymphoblastic leukemia显示文摘Background:T-cell acute lymphoblastic leukemia(T-ALL)is an uncommon and aggressive subtype of acute lymphoblastic leukemia(ALL).In the serum of T-ALL patients,the activity of lactate dehydrogenase A(LDHA)is increased.We proposed that targeting LDHA may be a potential strategy to improve T-ALL outcomes.The current study was conducted to investigate the antileukemic effect of LDHA gene-targeting treatment on T-ALL and the underlying molecular mechanism.Methods:Primary T-ALL cell lines Jurkat and DU528 were treated with the LDH inhibitor oxamate.MTT,colony formation,apoptosis,and cell cycle assays were performed to investigate the effects of oxamate on T-ALL cells.Quantitative real-time PCR(qPCR)and Western blotting analyses were applied to determine the related signaling pathways.A mitochondrial reactive oxygen species(ROS)assay was performed to evaluate ROS production after T-ALL cells were treated with oxamate.A T-ALL transgenic zebrafish model with LDHA gene knockdown was established using CRISPR/Cas9 gene-editing technology,and then TUNEL,Western blotting,and T-ALL tumor progression analyses were conducted to investigate the effects of LDHA gene knockdown on T-ALL transgenic zebrafish.Results:Oxamate significantly inhibited proliferation and induced apoptosis of Jurkat and DU528 cells.It also arrested Jurkat and DU528 cells in G0/G1 phase and stimulated ROS production(all P<0.001).Blocking LDHA significantly decreased the gene and protein expression of c-Myc,as well as the levels of phosphorylated serine/threonine kinase(AKT)and glycogen synthase kinase 3 beta(GSK-3β)in the phosphatidylinositol 3′-kinase(PI3K)signaling pathway.LDHA gene knockdown delayed disease progression and down-regulated c-Myc mRNA and protein expression in T-ALL transgenic zebrafish.Conclusion:Targeting LDHA exerted an antileukemic effect on T-ALL,representing a potential strategy for T-ALL treatment. | Haizhi Yu Yafei Yin Yifang Yi Zhao Cheng Wenyong Kuang Ruijuan Li Haiying Zhong Yajuan Cui Lingli Yuan Fanjie Gong Zhihua Wang Heng Li Hongling Peng Guangsen Zhang | 2020 | Cancer Communications2020，40，10： | 2 |
| 18 | Non-coding RNAs in hepatitis B or C-associated hepatocellular carcinoma: Potential diagnostic and prognostic markers and therapeutic targets显示文摘 | Qi Zhang Rui Pu Yan Du Yifang Han Tong Su Hongyang Wang Guangwen Cao | 2012 | Cancer Letters2012，，1： | 1 |
| 19 | Preparation of iron-tungsten-boron alloy deposits by electroless plating 显示文摘 | Yi Ge Wang Lingling Ouyang Yifang | 1996 | Metal Finnishing1996，94，11： | 1 |
| 20 | Association of a potential functional pre‐miR‐218 polymorphism and its interaction with hepatitis B virus mutations with hepatocellular carcinoma risk显示文摘 | Yifang Han Rui Pu Xue Han Jun Zhao Weiping Li Jianhua Yin Yuwei Zhang Qiuxia Shen Jiaxin Xie Qi Zhang Shuang Jiang Juhong Li Hongwei Zhang Hongyang Wang Guangwen Cao | 2014 | Liver Int2014，，5： | 1 |
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