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| 1 | Highly efficient induction and long-term maintenance of multipotent cardiovascular progenitors from human pluripotent stem cells under defined conditions显示文摘心血管的祖先房间( CVPC )源于人的 pluripotent 干细胞( hPSCs ),包括人的胚胎的干细胞( hESCs )和人的导致的 pluripotent 干细胞( hiPSCs ),为心血管的开发和心疾病的基于房间的治疗的学习的抓住伟人诺言,但是他们的应用被困难在他们的有效产生和稳定的维护质问。这研究试图由关键早发展的小径在人的心血管的说明和 CVPC 自强包含了的 modulating 为柔韧的产生和导出 hPSC 的 CVPC 的稳定的繁殖开发化学上定义的系统。此处,我们报导那骨头的联合形态基因的蛋白质 4 (BMP4 ) ,肝糖 synthase kinase 3 (GSK3 ) 禁止者 CHIR99021 和维生素酸是足够的很快变换单层有教养的 hPSCs 包括 hESCs 和 hiPSCs,调节进在在喂免费、没有浆液的文化下面的化学上定义的媒介的同类的 CVPC。在喂免费、没有浆液的条件下面稳定地自我更新、在 10 7-fold 上膨胀的这些 CVPC 从 BMP, GSK3 和 Activin/Nodal 小径的导致区别的信号是什么时候,同时消除了。而且,这些 CVPC 在 vitro 展出了 CVPC,包括 cardiomyocytes 产生主要的心血管的系的保留的潜力,光滑的肌肉房间和 endothelial 房间的期望的染色体宽的分子的特征,并且是在 vivo 的 non-tumorigenic。总的来说,这里报导的确定的系统允许有效产生和导出 hPSC 的 CVPC 的稳定的维护,它代表一个强大的工具学习早胚胎的心血管的开发并且为心肌的再生药提供房间的潜在地安全的来源。 | Nan Cao He Liang Jijun Huang Jia Wang Yixiong Chen Zhongyan Chen Huang-Tian Yang | 2013 | Cell Research2013，23，9： | 12 |
| 2 | Optimization and control of a reactive distillation process for the synthesis of dimethyl carbonate显示文摘Dimethyl carbonate is an environmentally benign and biodegradable chemical.Based on integration of reactive distillation and pressure-swing distillation technologies,a novel process for synthesis of dimethyl carbonate through transesterification with propylene carbonate and methanol has been developed by Huang et al.In this work,the optimization of this process was performed by minimizing the total TAC.The results show that the optimal design flowsheet can save energy consumption by 18.6% with the propylene carbonate conversion of 99.9%.Then,an effective plant-wide control structure for the process was developed.Dynamic simulation results demonstrate that the temperature/flow rate cascade control plus with simple temperature control can keep not only product purity but also the conversion of the reactant at their desired values in the face of the disturbance in reactant feed flow rate and feed composition. | Zhixian Huang Yixiong Lin Xiaoda Wang Changshen Ye Ling Li | 2017 | Chinese Journal of Chemical Engineering2017，25，8： | 8 |
| 3 | Non-axisymmetric Flow Characteristics in Centrifugal Compressor显示文摘The flow field distribution in centrifugal compressor is significantly affected by the non-axisymmetric geometry structure of the volute.The experimental and numerical simulation methods were adopted in this work to study the compressor flow field distribution with different flow conditions.The results show that the pressure distribution in volute is characterized by the circumferential non-uniform phenomenon and the pressure fluctuation on the high static pressure zone propagates reversely to upstream,which results in the non-axisymmetric flow inside the compressor.The non-uniform level of pressure distribution in large flow condition is higher than that in small flow condition,its effect on the upstream flow field is also stronger.Additionally,the non-uniform circumferential pressure distribution in volute brings the non-axisymmetric flow at impeller outlet.In different flow conditions,the circumferential variation of the absolute flow angle at impeller outlet is also different.Meanwhile,the non-axisymmetric flow characteristics in internal impeller can be also reflected by the distribution of the mass flow.The high static pressure region of the volute corresponds to the decrease of mass flow in upstream blade channel,while the low static pressure zone of the volute corresponds to the increase of the mass flow.In small flow condition,the mass flow difference in the blade channel is bigger than that in the large flow condition. | WANG Leilei LAO Dazhong LIU Yixiong YANG Ce | 2015 | Journal of Thermal Science2015，24，4： | 7 |
| 4 | Hot corrosion behavior of nanostructured Gd2O3 doped YSZ thermal barrier coating in presence of Na2SO4+V2O5 molten salts显示文摘Nickel-based superalloy DZ125 was first sprayed with a NiCrAlY bond coat and followed with a nanostructured 2 mol% Gd_2O_3-4.5 mol% Y_2 O_3-ZrO_2(2 GdYSZ) topcoat using air plasma spraying(APS). Hot corrosion behavior of the as-sprayed thermal barrier coatings(TBCs) were investigated in the presence of 50 wt%Na_2SO_4 + 50 wt% V_2O_5 as the corrosive molten salt at 900 ℃ for 100 h. The analysis results indicate that Gd doped YVO_4 and m-ZrO_2 crystals were formed as corrosion products due to the reaction of the corrosive salts with stabilizers(Y_2O_3, Gd_2O_3) of zirconia. Cross-section morphology shows that a thin layer called TGO was formed at the bond coat/topcoat interface. After hot corrosion test, the proportion of m-ZrO_2 phase in nanostructured 2GdYSZ coating is lower than that of nano-YSZ coating. The result reveals that nanostructured 2GdYSZ coating exhibits a better hot corrosion resistance than nano-YSZ coating. | Yixiong Wang Chungen Zhou | 2017 | Progress in Natural Science:Materials International2017，27，4： | 7 |
| 5 | Using in situ REE analysis to study the origin and diagenesis of dolomite of Lower Paleozoic,Tarim Basin显示文摘In situ REE concentrations of various dolomites from Tarim Basin were obtained by LA-ICP-MS analysis,and the data were normalized to standard seawater(Seawater Normalized=SWN).Most of the samples have a ΣREE range of less than 20 ppm.All samples show similar REESWN distributions with heavy REE depletion,and positive Ce anomaly,which indicates that they have the same dolomitization fluids(seawater).According to the origin and diagenetic process of dolomite,two types of dolomite are determined and described as follows:1) syndepositional dolomite,with the highest REE concentrations(more than 20 ppm),the cores of which are more enriched in REE compared with their cortexes,indicating that they underwent the dolomitization of calcareous sediments by hypersaline and subsequent diagenesis decreased the REE content of the cortex because of the low REE concentration of the diagenetic fluids;2) diagenetic dolomite,which can be subdivided into four groups.(1) burial dolomite which has higher REE concentrations than limestone,but lower than syndepositional dolomite.This shows that pore fluids with high salinity dolomitized the pre-existing limestone;(2) void filling dolomite which has the similar REE patterns with the matrix dolomite.In addition,the Eu anomaly is not obvious,suggesting that the dolomitization fluids originated from the diagenetic fluids;(3) recrystallized dolomite,whose REE concentration was obviously decreased,indicating that the REE concentration was decreased during the recrystallization processes;and(4) hydrothermal altered void-filling dolomite,which has the lowest REE concentration,but obvious positive Eu anomaly,reflecting its hydrothermal activity related origin.Thus,the diverse REE signatures,which were recorded in different dolomites,retain the information of their formation conditions and subsequent diagenetic processes.In situ REE analysis of dolomite is an effective probe into the origin and diagenetic process of dolomite. | WANG XiaoLin JIN ZhiJun HU WenXuan ZHANG JunTao QIAN YiXiong ZHU JingQuan LI Qing | 2009 | Science China Earth Sciences2009，52，5： | 7 |
| 6 | Effect of Gd_2O_3 on the microstructure and thermal properties of nanostructured thermal barrier coatings fabricated by air plasma spraying显示文摘The nanostructured 4–8 mol% Gd_2O_3-4.5 mol% Y_2O_3-ZrO_2(4–8 mol% Gd YSZ) coatings were developed by the atmospheric plasma spraying technique. The microstructure and thermal properties of plasmasprayed 4–8 mol% Gd YSZ coatings were investigated. The experimental results indicate that typical microstructure of the as-sprayed coatings were consisted of melted zones, nano-zones, splats, nano-pores,high-volume spheroidal pores and micro-cracks. The porosity of the 4, 6 and 8 mol% Gd YSZ coatings was about 9.3%, 11.7% and 13.3%, respectively. It was observed that the addition of gadolinia to the nano-YSZ could significantly reduce the thermal conductivity of nano-YSZ. The thermal conductivity of Gd YSZ decreased with increasing Gd_2O_3 addition. And the reduction in thermal conductivity is mainly attributed to the addition of Gd_2O_3, which results in the increase in oxygen vacancies, lattice distortion and porosity. | Yixiong Wang Chungen Zhou | 2016 | Progress in Natural Science:Materials International2016，26，4： | 6 |
| 7 | REE Compositions of Lower Ordovician Dolomites in Central and North Tarim Basin,NW China:A Potential REE Proxy for Ancient Seawater显示文摘摘要:在中央、北的 Tarim 盆的更低的奥陶纪白云石的稀土元素元素作文被学习。大多数白云石样品被泥土矿物质差不多污染。他们的稀土元素元素作文因而被改变了,出现像海水并且 non-seawater-like 特征。在 REE 数据被使用以前,泥土污染应该被处理。通过 ICPMS 和 ICP-AES 分析, REE 特征很好被记录。泥土污染是显微镜的调查,踪迹元素和 REE 内容决定的份量上。至少在 Tarim 盆,当他们的全部的 LREE 内容是不到 3times10 时,白云石被认为纯 ? 6。通过比较,纯白云石在 REE 模式显示出类似但是在 REE 的差别与共存的纯石灰石满足,它显示化成白云石可以稍微改变 REE 作文。不过,变化是无论什么,纯白云石可以为奥陶纪海水充当一个潜在的 REE 代理,它将为缺乏石灰石的古老的巨大的白云石阶层是重要的。 | ZHANG Xuefeng HU Wenxuan JIN Zhijun ZHANG Juntao QIAN Yixiong ZHU Jingquan ZHU Dongya WANG Xiaolin XIE Xiaomin | 2008 | Acta Geologica Sinica(English Edition)2008，82，3： | 3 |
| 8 | Spatio-temporal Variation of Landscape Heterogeneity under Influence of Human Activities in Xiamen City of China in Recent Decade显示文摘Xiamen is an economically competitive and highly urbanized city along the coastal area of Fujian Province, China. The research on spatio-temporal variation of landscape heterogeneity under the influence of human activities is of great importance to the further study on the relationship of landscape pattern and ecological process. It is also crucial to the discovery of spatial variation and intensity distribution of human activities. The research analyzed the intensity of human impacts and the spatial variation features and dynamics of landscape patterns by introducing statistical theories and approaches. We analyzed spatio-temporal variation of landscape heterogeneity using the geostatistical techniques, such as semivariogram and Kriging interpolation.Results show that there is a higher correlation between landscape heterogeneity indexes and human impact index. Both the indexes show a moderate spatial autocorrelation as well as an obvious characteristic of anisotropy. From 1998 to 2008, the spatial differentiation of the changes in the intensity of human activities and the changes in landscape heterogeneity shows that the landscape patterns in Xiamen are closely related with the urban land utilization methods, the condition of traffic and geographical location and the physical geographical condition such as the terrain and the ecological environment. The process of urbanization has a significant impact on the urban landscape pattern. | HUANG Yixiong YIN Xiuqin YE Gongfu LIN Jiemin HUANG Ru WANG Na WANG Liang SUN Yue | 2013 | Chinese Geographical Science2013，23，2： | 3 |
| 9 | Failure Detection and Correction for Appearance Based Facial Tracking显示文摘The appearance based facial tracking methods, such as active appearance models and candide models, are widely used in intelligent user interface and facial expression recognition. This paper proposes a novel method to detect and correct the failures in appearance based facial tracking. A sparse coding strategy is applied to learn an efficient feature representation for the difference between the warped image and the face template. The features are extracted by directly pro ject the difference image to the space spanned by the dictionary of the sparse coding. An iterative regression based method is proposed to detect and correct the failures according to the features. Experimental evaluation on an open dataset shows a global performance improvement of the tracking algorithm. | WANG Lei LIANG Yixiong CAI Wangyang ZOU Beiji | 2015 | Chinese Journal of Electronics2015，24，1： | 3 |
| 10 | Standard pancreatoduodenectomy versus extended pancreatoduodenectomy with modified retroperitoneal nerve resection in patients with pancreatic head cancer:a multicenter randomized controlled trial显示文摘Background:The extent of pancreatoduodenectomy for pancreatic head cancer remains controversial,and more high-level clinical evidence is needed.This study aimed to evaluate the outcome of extended pancreatoduodenectomy(EPD)with retroperitoneal nerve resection in pancreatic head cancer.Methods:This multicenter randomized trial was performed at 6 Chinese highvolume hospitals that enrolled patients between October 3,2012,and September 21,2017.Four hundred patients with stage I or II pancreatic head cancer and without specific pancreatic cancer treatments(preoperative chemotherapy or chemoradiation)within three months were randomly assigned to undergo standard pancreatoduodenectomy(SPD)or EPD,with the latter followed by dissection of additional lymph nodes(LNs),nerves and soft tissues 270◦on the right side surrounding the superior mesenteric artery and celiac axis.The primary endpoint was overall survival(OS)by intention-to-treat(ITT).The secondary endpoints were disease-free survival(DFS),mortality,morbidity,and postoperative pain intensity.Results:TheR1 ratewas slightly lower with EPD(8.46%)thanwith SPD(12.56%).The morbidity and mortality rates were similar between the two groups.The median OS was similar in the EPD and SPD groups by ITT in the whole study cohort(23.0 vs.20.2 months,P=0.100),while the median DFS was superior in the EPD group(16.1 vs.13.2 months,P=0.031).Patients with preoperative CA19–9<200.0 U/mL had significantly improved OS and DFS with EPD(EPD vs.SPD,30.8 vs.20.9 months,P=0.009;23.4 vs.13.5 months,P<0.001).The EPD group exhibited significantly lower locoregional(16.48%vs.35.20%,P<0.001)andmesenteric LNrecurrence rates(3.98%vs.10.06%,P=0.022).The EPD group exhibited less back pain 6 months postoperation than the SPD group.Conclusions:EPD for pancreatic head cancer did not significantly improve OS,but patients with EPD treatment had significantly improved DFS.In the subgroup analysis,improvements in bothOS and DFS in the EPD armwere observed in patients with preoperative CA19–9<200.0 U/mL.EPD could be used as an effective surgical procedure for patients with pancreatic head cancer,especially those with preoperative CA19–9<200.0 U/mL. | Qing Lin Shangyou Zheng Xianjun Yu Meifu Chen Yu Zhou Quanbo Zhou Chonghui Hu Jing Gu Zhongdong Xu LinWang Yimin Liu Qingyu Liu MinWang Guolin Li He Cheng Dongkai Zhou Guodong Liu Zhiqiang Fu Yu Long Yixiong Li Weilin Wang Renyi Qin Zhihua Li Rufu Chen | 2023 | Cancer Communications2023，43，2： | 3 |
| 11 | The fatty acid composition of colostrum in three geographic re- gions of China 显示文摘 | GAO Yixiong ZHANG Jian WANG Chunrong | 2013 | Asia Pac J Clin Nutr2013，22，2： | 1 |
| 12 | The fatty acid composition of colostrum in three geographic regions of China显示文摘 | GAO Yixiong ZANG Jian WANG Chunrong | 2013 | Asia Pac J Clin Nutr2013，22，2： | 1 |
| 13 | Different intakes of n-3 fatty acids among pregnant women in 3 regions of China with contrasting dietary patterns are reflected in maternal but not in umbilical erythrocyte phosphatidylcholine fatty acid composition显示文摘 | ZHANG Jian WANG Chunrong GAO Yixiong | 2013 | Nutr Res2013，33，8： | 1 |
| 14 | Investigation on Inlet Recirculation Characteristics of Double Suction Centrifugal Compressor with Unsymmetrical Inlet显示文摘The inlet recirculation characteristics of double suction centrifugal compressor with unsymmetrical inlet structures were studied in numerical method,mainly focused on three issues including the amounts and differences of the inlet recirculation in different working conditions,the circumferential non-uniform distributions of the inlet recirculation,the recirculation velocity distributions of the upstream slot of the rear impeller.The results show that there are some differences between the recirculation of the front impeller and that of the rear impeller in whole working conditions..In design speed,the recirculation flow rate of the rear impeller is larger than that of the front impeller in the large flow range,but in the small flow range,the recirculation flow rate of the rear impeller is smaller than that of the front impeller.In different working conditions,the recirculation velocity distributions of the front and rear impeller are non-uniform along the circumferential direction and their non-uniform extents are quite different.The circumferential non-uniform extent of the recirculation velocity varies with the working conditions change.The circumferential non-uniform extent of the recirculation velocity of front impeller and its distribution are determined by the static pressure distribution of the front impeller,but that of the rear impeller is decided by the coupling effects of the inlet flow distortion of the rear impeller,the circumferential unsymmetrical distribution of the upstream slot and the asymmetric structure of the volute.In the design flow and small flow conditions,the recirculation velocities at different circumferential positions of the mean line of the upstream slot cross-section of the rear impeller are quite different,and the recirculation velocities distribution forms at both sides of the mean line are different.The recirculation velocity distributions in the cross-section of the upstream slot depend on the static pressure distributions in the intake duct. | YANG Ce WANG Yingjun LAO Dazhong TONG Ding WEI Longyu LIU Yixiong | 2016 | Journal of Thermal Science2016，25，4： | 1 |
| 15 | Formation of saddle dolomites in Upper Cambrian carbonates, western Tarim Basin (northwest China): Implications for fault-related fluid flow显示文摘 | Juntao Zhang Wenxuan Hu Yixiong Qian Xiaolin Wang Jian Cao Jingquan Zhu Qing Li Xiaomin Xie | 2009 | Marine and Petroleum Geology2009，，8： | 1 |
| 16 | Evaluation model for arc fluctuations of triple-electrode high speed fillet welding显示文摘 | Ma Xiaoli Hua Xueming Wang Fei Wu Yixiong | 2014 | China Welding2014，23，2： | 1 |
| 17 | Residual stresses in coating-based systems, part I: Mechanisms and analytical modeling显示文摘 | Xiancheng Zhang Yixiong Wu Binshi Xu Haidou Wang | 2007 | Frontiers of Mechanical Engineering in China2007，，1： | 1 |
| 18 | Molecular correlation of crude oils and oil components from reservoir rocks in the Tazhong and Tabei uplifts of the Tarim Basin, China 显示文摘 | Yu Shuang Pan Changchun Wang Jinji Jin Xiaodong Jiang Lanlan Liu Dayong LiJ Xiuxiang Qin Jianzhong Qian Yixiong Ding Yong Chen | 2011 | Org Geochem2011，42，10： | 1 |
| 19 | Guidelines for the diagnosis and treatment of acute pancreatitis in China (2021)显示文摘Acute pancreatitis(AP)is a common acute abdominal condition of the digestive system.In recent years,treatment concepts,methods,and strategies for the diagnosis of AP have advanced,and this has played an important role in promoting the standardization of AP diagnosis and treatment and improving the treatment quality of AP patients.On the basis of previous guidelines and expert consensus,this guideline adopts an evidence-based,problem-based expression;synthesizes important clinical research data at home and abroad in the most recent 5 years;and forms 29 recommendations through multidisciplinary expert discussion,including diagnosis,treatment,and follow-up.It is expected to provide evidence support for the treatment of AP in the clinical setting in China. | Fei Li Shouwang Cai Feng Cao Rufu Chen Deliang Fu Chunlin Ge Chunyi Hao Jihui Hao Heguang Huang Zhixiang Jian Gang Jin Ang Li Haimin Li Shengping Li Weiqin Li Yixiong Li Tingbo Liang Xubao Liu Wenhui Lou Yi Miao Yiping Mou Chenghong Peng Renyi Qin Chenghao Shao Bei Sun Guang Tan Xiaodong Tian Huaizhi Wang Lei Wang Wei Wang Weilin Wang Junmin Wei Heshui Wu Wenming Wu Zheng Wu Changqing Yan Yinmo Yang Xiaoyu Yin Xianjun Yu Chunhui Yuan Taiping Zhang Yupei Zhao on behalf of the Chinese Pancreatic Surgery Association | 2021 | Journal of Pancreatology2021，4，2： | 1 |
| 20 | Residual stresses in coating-based systems, part I: Mechanisms and analytical modeling显示文摘 | Xiancheng Zhang Yixiong Wu Binshi Xu Haidou Wang | 2007 | Frontiers of Mechanical Engineering in China2007，，1： | 1 |
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