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| 1 | Clinical efficacy of 0.1% pranoprofen in treatment of dry eye patients:a multicenter, randomized, controlled clinical trial显示文摘 | Chen Jingyao Dong Fei Chen Wei Sun Xuguang Deng Yingping Hong Jing Zhang Mingchang Yang Wenzhao Liu Zuguo Xie Lixin | 2014 | Chinese Medical Journal2014，，13： | 18 |
| 2 | Degradation of organic pollutants by a Co_3O_4 -graphite composite electrode in an electro-Fenton-like system显示文摘A novel composite electrode was constructed by pressing together Co3O4 and graphite and it was used as the cathode in an electro-Fenton-like (EFL) system. The poor electron transport characteristic of Co3O4 was overcome by incorporating graphite. In situ electro-catalytic generation of hydroxyl radicals (·OH) occurred at high current efficiencies from pH 2-10, extending the traditional Fenton reaction pH range. Cyclic voltammetry and AC impedance spectrometry were used to characterize the composite electrode. The ability of the EFL system to degrade organic compounds was investigated using sulforhodamine B (SRB) and 2,4-dichlorophenol (2,4-DCP) as probes. Decoloration of SRB (1.0×10-5 mol/L) was complete (100%) in 150 min and SRB was effectively degraded from pH 2-10. The decomposition of SRB was studied using Fourier transform infrared spectroscopy (FT-IR) and total organic carbon (TOC) analysis and results indicated that the final degradation products were carbon dioxide, carboxylic acids and amines. The EFL system also decomposed 2,4-DCP and the degradation was 98.6% in 240 min. Electro-catalytic degradation of SRB occurs by a ·OH mechanism. After 5 times reused, the degradation rate of SRB did not significantly slow down. The electrode shows excellent potential for use in advanced oxidation processes (AOPs) used to treat persistent organic pollutants (POPs) in wastewater. | LIU Shuan GU Yan WANG ShuLian ZHANG Yu FANG YanFen JOHNSON David M HUANG YingPing | 2013 | Chinese Science Bulletin2013，58，19： | 18 |
| 3 | Preparation and application of ZnO doped Pt-CeO2 nanofibers as electrocatalyst for methanol electro-oxidation显示文摘ZnO doped Pt/CeO_2 nanocomposites were prepared by electrospinning and reduction impregnation.Xray diffraction(XRD),transmission electron microscopy(TEM),energy disperse spectroscopy(EDS) and X-ray photoelectron spectroscopy(XPS) were employed to characterize the nanocomposites.It is observed that ZnO and CeO_2 form the hexagonal wurtzite phase and cubic fluorite phase in the nanocomposite,respectively,whilst Pt nanoparticles(NPs) with the number-averaged size of ca.3.1 nm are uniformly distributed on the surface of nanofibers.The mass fraction of Pt NPs in the nanocomposites is about 10 wt%.The doping of ZnO is effective to promote reactive oxygen species,surface reaction sites and the interaction between Pt and oxides.The catalytic performance of nanocomposites was evaluated by the methanol electro-oxidation.indexed with the catalytic activity,stability of catalyst.As a result,it is found that the nanocomposite exhibits much higher activity and stability for methanol oxidation than the undoped Pt/CeO_2 catalyst. | Yingping Zheng Xin Zhang Zhengying Zhang Ying Li Yueming Sun Yongbing Lou Xiaojun Li Yang Lu | 2018 | Journal of Rare Earths2018，36，9： | 5 |
| 4 | Recent progress in organic solar cells(PartⅠmaterial science)显示文摘During past several years,the photovoltaic performances of organic solar cells(OSCs)have achieved rapid progress with power conversion efficiencies(PCEs)over 18%,demonstrating a great practical application prospect.The development of material science including conjugated polymer donors,oligomer-like organic molecule donors,fused and nonfused ring acceptors,polymer acceptors,single-component organic solar cells and water/alcohol soluble interface materials are the key research topics in OSC field.Herein,the recent progress of these aspects is systematically summarized.Meanwhile,the current problems and future development are also discussed. | Yahui Liu Bowen Liu Chang-Qi Ma Fei Huang Guitao Feng Hongzheng Chen Jianhui Hou Lingpeng Yan Qingya Wei Qun Luo Qinye Bao Wei Ma Wei Liu Weiwei Li Xiangjian Wan Xiaotian Hu Yanchun Han Yaowen Li Yinhua Zhou Yingping Zou Yiwang Chen Yongfang Li Yongsheng Chen Zheng Tang Zhicheng Hu Zhi-Guo Zhang Zhishan Bo | 2022 | Science China Chemistry2022，65，2： | 5 |
| 5 | Recent progress in organic solar cells(PartⅡdevice engineering)显示文摘1 Introduction Organic solar cells(OSCs)belong to a multidisciplinary field composed of chemistry,materials science,physics,engineering,etc.For a better reviewing of this field,we briefly divide the research field of OSCs into two parts:material science and device engineering.In our previous review,the material science part of OSCs,including conjugated polymer donors and acceptors,small molecular donors and acceptors. | Yahui Liu Bowen Liu Chang-Qi Ma Fei Huang Guitao Feng Hongzheng Chen Jianhui Hou Lingpeng Yan Qingya Wei Qun Luo Qinye Bao Wei Ma Wei Liu Weiwei Li Xiangjian Wan Xiaotian Hu Yanchun Han Yaowen Li Yinhua Zhou Yingping Zou Yiwang Chen Yuqiang Liu Lei Meng Yongfang Li Yongsheng Chen Zheng Tang Zhicheng Hu Zhi-Guo Zhang Zhishan Bo | 2022 | Science China Chemistry2022，65，8： | 3 |
| 6 | A Novel Readout System for Wireless Passive Pressure Sensors显示文摘这份报纸基于诱导地联合的电感器和洞(LC ) 为无线被动压力传感器论述一个新奇读出系统反响的电路。建议系统由诱导地联合到传感器电路,一个读出电路,和处理联合起来的一张个人计算机(PC ) 帖子的一条阅读器天线组成。读出电路产生代表传感器电容的一个电压信号。驾驶信号的读者天线的频率是一个常数,它等于传感器在零个压力的反响的频率。基于机械、电建模,压力传感器设计基于高温度共同开火陶器(HTCC ) 技术被进行并且讨论。读出系统的功能和精确性与一个电压电容测量系统被测试并且在现实主义的压力测量环境示威了,以便全面表演和读出系统的可行性被证明。 | Huixin Zhang Yingping Hong Binger Ge Ting Liang Jijun Xiong | 2014 | Photonic Sensors2014，4，1： | 2 |
| 7 | Neglected Rural Public Health Issue:The Case of Intestinal Roundworms显示文摘Despite increasing institutional and financial support,certain public health issues are still neglected by the Chinese Government.The present paper examines the soil-transmitted helminth(STH)infection and reinfection rates by conducting a survey on 1724 children in Guizhou Province,China.Our results indicate that 37.5 percent of children had been infected with one or more of the three types of tested STH.However,only 50.4 percent of children reported having taken deworming medicine during the 18-month period before the survey.Of those who reported being dewormed,34.6 percent tested positive for STH infections.Poverty and number of siblings are significantly and positively correlated with infection and reinfection,and parental education is significantly and negatively correlated with infection and reinfection.Given the ineffectiveness of treatment in these areas to date,for anthelmintic campaigns to actually succeed,China must pay more attention to locallevel incentives to improve children's health. | Linxiu Zhang Yingping Cai Xiaobing Wang Xiaochen Ma Alexis Medina D.Scott Smith Scott Rozelle | 2013 | China & World Economy2013，21，3： | 2 |
| 8 | 20(R)-ginsenoside Rg3,a product of high-efficiency thermal deglycosylation of ginsenoside Rd,exerts protective effects against scrotal heat-induced spermatogenic damage in mice显示文摘Heat stress(HS)reaction can lead to serious physiological dysfunction associated with cardiovascular and various organ diseases.Ginsenoside Rg3(G-Rg3)is a representative component of ginseng rare saponin and can protect against multiple organs,also used as functional food to adjust the balance of the human body,but the therapeutic effect and molecular mechanism of G-Rg3 on male diseases under HS are underexplored.The aim of the present study,G-Rg3 was prepared through the efficient conversion of ginsenoside Rd and investigate the contribution of G-Rg3 to testicular injury induced exposure to HS.All mice were divided into four groups as follows:normal group,HS group,and HS+G-Rg3(5 and 10 mg/kg)groups.G-Rg3 was administered orally for 14 days,then exposed to a single scrotal heat treatment(43°C,18min)on the 7th day.After HS treatment,the morphology of testis and epididymis changes,and caused a significant loss of multinucleated giant cells,desquamation of germ cells in destructive seminiferous tubules,and degenerative Leydig cells,further destroying the production of sperm.After administration G-Rg3(5 and 10 mg/kg/day)for 2 weeks,the spermatogenic-related indexes of testosterone levels and superoxide dismutase(SOD)activity,glutathione(GSH)content significantly(p<0.01)increase compared with the HS group.Moreover,G-Rg3 treatment effectively ameliorated the production of malondialdehyde(MDA)(p<0.05 or p<0.01).Importantly,G-Rg3 exhibited the protective potential against HS-induced injury not only suppressing the protein levels of heme oxygenase-1(HO-1),hypoxia-inducible factor-1α(HIF-1α),and heat shock protein 70(HSP70)but also modulating the Bcl-2 family(p<0.01 or p<0.001)and activation of mitogen-activated protein kinase(MAPK)signaling pathways(p<0.01).For most of the parameters tested,the HS+G-Rg3(10 mg/kg)group exhibited potent effects compared with those exhibited by the low dose(5 mg/kg)group.In conclusion,the present study demonstrated that G-Rg3 exerted protective effects against HS-induced testicular dysfunction via inhibiting the MAPK-mediated oxidative stress and apoptosis in mice. | WEI LIU ZI WANG JING LENG HENG WEI SHEN REN XIAOJIE GONG CHEN CHEN YINGPING WANG RUI ZHANG WEI LI | 2020 | BIOCELL2020，44，4： | 2 |
| 9 | Efficacy,safety and immunogenicity of hexavalent rotavirus vaccine in Chinese infants显示文摘A randomized,double-blind,placebo-controlled multicenter trial was conducted in healthy Chinese infants to assess the efficacy and safety of a hexavalent live human-bovine reassortant rotavirus vaccine(HRV)against rotavirus gastroenteritis(RVGE).A total of 6400 participants aged 6-12 weeks were enrolled and randomly assigned to either HRV(n?3200)or placebo(n?3200)group.All the subjects received three oral doses of vaccine four weeks apart.The vaccine efficacy(VE)against RVGE caused by rotavirus serotypes contained in HRV was evaluated from 14 days after three doses of administration up until the end of the second rotavirus season.VE against severe RVGE,VE against RVGE hospitalization caused by serotypes contained in HRV,and VE against RVGE,severe RVGE,and RVGE hospitalization caused by natural infection of any serotype of rotavirus were also investigated.All adverse events(AEs)were collected for 30 days after each dose.Serious AEs(SAEs)and intussusception cases were collected during the entire study.Our data showed that VE against RVGE caused by serotypes contained in HRV was 69.21%(95%CI:53.31-79.69).VE against severe RVGE and RVGE hospitalization caused by serotypes contained in HRV were 91.36%(95%CI:78.45-96.53)and 89.21%(95%CI:64.51-96.72)respectively.VE against RVGE,severe RVGE,and RVGE hospitalization caused by natural infection of any serotype of rotavirus were 62.88%(95%CI:49.11-72.92),85.51%(95%CI:72.74-92.30)and 83.68%(95%CI:61.34-93.11).Incidences of AEs from the first dose to one month post the third dose in HRV and placebo groups were comparable.There was no significant difference in incidences of SAEs in HRV and placebo groups.This study shows that this hexavalent reassortant rotavirus vaccine is an effective,well-tolerated,and safe vaccine for Chinese infants. | Zhiwei Wu Qingliang Li Yan Liu Huakun Lv Zhaojun Mo Fangjun Li Qingchuan Yu Fei Jin Wei Chen Yong Zhang Teng Huang Xiaosong Hu Wei Xia Jiamei Gao Haisong Zhou Xuan Bai Yueyue Liu Zhenzhen Liang Zhijun Jiang Yingping Chen Jiuwei Zhang Jialiang Du Biao Yang Bo Xing Yantao Xing Ben Dong Qinghai Yang Chen Shi Tingdong Yan Bo Ruan Haiyun Shi Xingliang Fan Dongyang Feng Weigang Lv Dong Zhang Xiangchu Kong Liuyifan Zhou Dinghong Que Hong Chen Zhongbing Chen Xiang Guo Weiwei Zhou Cong Wu Qingrong Zhou Yuqing Liu Jian Qiao Ying Wang Xinguo Li Kai Duan Yuliang Zhao Gelin Xu Xiaoming Yang | 2022 | Virologica Sinica2022，37，5： | 2 |
| 10 | Screening of Benzoic Acid Biodegradation Strains显示文摘Three strains BQ,BJ,and BS utilizing benzoic acid as the sole carbon source were achieved from Yichang City,Hubei Province,China,through selective enrichment and domestication.Both BQ and BJ were primarily identified as Acinetobacter.spp while BS was Geotrichum.spp.After three domestications,the removal rates of BQ,BJ,and BS to chemical oxygen demand(COD) value of benzoic acid were 62.41%,94.44%,and 43.34%,respectively.The strains were mixed cultured,and the degradation rates of strains to benzoic acid at different temperature,pH and benzoic acid concentration were determined.The results show that the optimum degradation conditions about strains were pH 7.0,temperature 30 ℃,and aerobic with 1 500 mg/L of concentration of benzoic acid.In this condition,the COD removal rate of strains to benzoic acid reached 84.93%. | WANG Shulian,ZHANG Liping,WANG Xiaoxing,CHEN Dengxia,LI Xiaocong,HUANG Yingping Alan G.MacDiarmid Research Institute of Renewable Energy,China Three Gorges University,Yichang 443002,Hubei,China | 2010 | Wuhan University Journal of Natural Sciences2010，15，6： | 2 |
| 11 | Ore prospecting model and targets for the Dashuigou tellurium deposit, Sichuan Province, China显示文摘The Dashuigou tellurium(Te) deposit in Shimian city, Sichuan Province is the only known independent Te ore deposit in China. Samples were collected by1/50,000 stream sediment survey and analyzed by inductively coupled plasma–mass spectrometry, X-ray fluorescence spectrometry, emission spectrometry, and atomic absorption spectroscopy. An ore prospecting model for the Dashuigou Te deposit was then established. In the Dashuigou area, bismuth(Bi), Te, and gold(Au) concentrations in stream sediment samples displayed weak-positive anomalies, while silver(Ag) displayed a weaknegative anomaly. Bi, Te, Ag, and Au anomalies are regarded as indicators of Te deposits; the greater the ratio of Te+Bi/Au+Ag, the larger the possibility of an independent tellurobismuthite deposit. The ratio calculated from our samples is 7.288. Five locations were identified for prospecting for Te minerals by this model, including the northern part of the Dashuigou Te deposit, Majiagou,Tizigou, southeastern Miaoping, and northern Baishuihe.These five regions are within the Dashuigou dome anticline, the exposed strata of which are controlled by tracing the tensile shear fracture; the metallogenic geological conditions and geochemical characteristics are the same as those of the known Dashuigou Te deposit. Already, Te–Bi veins have been found in some of these areas. | Quanjiang Zhang Yingping Liu Mingyou He Jun Bai Wei Xu Cong Zhao | 2018 | Acta Geochimica2018，37，4： | 2 |
| 12 | Effect of γ-PGA Coated Urea on N-Release Rate and Tomato Growth显示文摘The anionic polymer γ-polyglutamic acid(γ-PGA) was used to coat urea and slow its dissolution. Three types of slow release urea(SRU) fertilizers(polymer coated urea with pore constriction, polymer coated urea with enzyme inhibitor and polymer coated urea with pore constriction and enzyme inhibitor) were prepared and tested for the N-release rate. After using SRU, the effect on the tomato growth was analyzed. The extracts of SRU were analyzed for NH3/NH4+-N and NO3--N. The N-release rate was used to determine the optimum ratio of ingredients. The results show that the three types of SRU met the dissolution rate standards recommended by the Committee of European Normalization. γ-PGA SRU increased the chlorophyll content of tomato(flowering stage) by an average of 100% compared with that grew in untreated urea. The results from soil analysis(0-60 cm in tomato pots) indicate that the content of NH3/NH4+-N in SRU-treated pots was 25%-61% higher than that in soil from urea-treated pots during the growing period,while the content of NO3--N was nearly 50% lower after the tomato had been harvested. Newly formulated SRU fertilizer increases nitrogen uptake and reduces loss of applied nitrogen. Plant growth is enhanced, a valuable resource is conserved, and the aquatic environment benefits from decreased level of nitrate in agricultural run-off. | JIANG Yue LIU Liming LUO Guangfu ZHANG Zhanli Davidmark J HUANG Yingping | 2014 | Wuhan University Journal of Natural Sciences2014，19，4： | 2 |
| 13 | Preparation, physical property and thermal physical property of phase change microcapsule slurry and phase change emulsion显示文摘 | Rui Yang Hui Xu Yingping Zhang | 2003 | Solar Energy Materials and Solar Cells2003，，4： | 1 |
| 14 | Direct rapid high-temperature alloy prototypeing by hybrid plasma-laser technology显示文摘 | Qian Yingping Huang Juhua Zhang Haiou | 2008 | Journal of Mate- rials Processing Technology2008，208，： | 1 |
| 15 | Wireless LTCC-based capacitive pressure sensor for harsh environment显示文摘 | Jijun Xiong Ying Li Yingping Hong Binzhen Zhang Tianhong Cui Qiulin Tan Shijun Zheng Ting Liang | 2013 | Physical2013，，： | 1 |
| 16 | Y6 and its derivatives:molecular design and physical mechanism显示文摘Non-fullerene-acceptor(NFA) materials in the bulk heterojunction(BHJ) play an important role in high-performance organic solar cells(OSCs). Recently,Y-series acceptors with an A-DA D-A structure have been a research hotspot and advanced device efficiency to 15%–18%. This perspective will focus on the discovery of Y6 and its derivatives as well as the intrinsic physical mechanism of Y-series-based devices, which provides a guideline for future molecular design. | Qingya Wei Jun Yuan Yuanping Yi Chunfeng Zhang Yingping Zou | 2021 | National Science Review2021，8，8： | 1 |
| 17 | Preparation, physical property and thermal physical property of phase change microcapsule slurry and phase change emulsion显示文摘 | Rui Yang Hui Xu Yingping Zhang | 2003 | Solar Energy Materials and Solar Cells2003，，4： | 1 |
| 18 | Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome显示文摘Organization of the genome into euchromatin and heterochromatin appears to be evolutionarily conserved and relatively stable during lineage differentiation.In an effort to unravel the basic principle underlying genome folding,here we focus on the genome itself and report a fundamental role for L1(LINE1 or LINE-1)and B1/Alu retrotransposons,the most abundant subclasses of repetitive sequences,in chromatin compartmentalization.We find that homotypic clustering of L1 and B1/Alu demarcates the genome into grossly exclusive domains,and characterizes and predicts Hi-C compartments.Spatial segregation of L1-rich sequences in the nuclear and nucleolar peripheries and B1/Alu-rich sequences in the nuclear interior is conserved in mouse and human cells and occurs dynamically during the cell cycle.In addition,de novo establishment of L1 and B1 nuclear segregation is coincident with the formation of higher-order chromatin structures during early embryogenesis and appears to be critically regulated by L1 and B1 transcripts.Importantly,depletion of L1 transcripts in embryonic stem cells drastically weakens homotypic repeat contacts and compartmental strength,and disrupts the nuclear segregation of L1-or B1-rich chromosomal sequences at genome-wide and individual sites.Mechanistically,nuclear co-localization and liquid droplet formation of L1 repeat DNA and RNA with heterochromatin protein HP1αsuggest a phase-separation mechanism by which L1 promotes heterochromatin compartmentalization.Taken together,we propose a genetically encoded model in which L1 and B1/Alu repeats blueprint chromatin macrostructure.Our model explains the robustness of genome folding into a common conserved core,on which dynamic gene regulation is overlaid across cells. | J.Yuyang Lu Lei Chang Tong Li Ting Wang Yafei Yin Ge Zhan Xue Han Ke Zhang Yibing Tao Michelle Percharde Liang Wang Qi Peng Pixi Yan Hui Zhang Xianju Bi Wen Shao Yantao Hong Zhongyang Wu Runze Ma Peizhe Wang Wenzhi Li Jing Zhang Zai Chang Yingping Hou Bing Zhu Miguel Ramalho-Santos Pilong Li Wei Xie Jie Na Yujie Sun Xiaohua Shen | 2021 | Cell Research2021，31，6： | 1 |
| 19 | Preparation, physical property and thermal physical property of phase change microcapsule slurry and phase change emulsion显示文摘 | Rui Yanga Hui Xu Yingping Zhang | 2003 | Solar Energy Materials & Solar Cells2003，80，4： | 1 |
| 20 | Association of growth rate with hormone levels and myogenic gene expression profile in broilers显示文摘Background: The growth rate often varies among individual broilers of the same breed under a common management condition. To investigate whether a variation in the growth rate is associated with a difference in hormone levels and myogenic gene expression profile in broilers, a feeding trial was conducted with 10,000 newly hatched Ross 308 chicks in a commercial production facility under standard management. At 38 d of age,30 fast-, 30 medium-, and 30 slow-growing broilers were selected among 600 healthy male individuals. The levels of insulin-like growth factor-1(IGF-1), triiodothyronine(T3), thyroxine(T4), and growth hormone in the serum or breast muscle were assayed by ELISA or RIA kits, and the expression levels of several representative pro-and anti-myogenic genes in the breast muscle were also measured by real-time PCR.Results: Results showed that both absolute and relative weights of the breast muscle were in linear positive correlations with the body weight of broilers(P < 0.001). Fast-growing broilers had higher concentrations of IGF-1 than slow-growing broilers(P < 0.05) in both the serum and breast muscle. The serum concentration of T3 was significantly higher in fast-growing birds than in slow-growing birds(P < 0.05). However, no difference was observed in growth hormone or T4 concentration among three groups of birds. Additionally, a decreased expression of an anti-myogenic gene(myostatin) and increased expressions of pro-myogenic genes such as myogenic differentiation factor 1, myogenin, muscle regulatory factor 4, myogenic factor 5, IGF-1, and myocyte enhancer factor 2B, C, and D were observed in fast-growing broilers(P < 0.05), relative to slow-growing broilers.Conclusions: Collectively, these findings suggested that the growth rate is linked to the hormone and myogenic gene expression levels in broiler chickens. Some of these parameters such as serum concentrations of IGF-1 and T3 could be employed to breed for enhanced growth. | Yingping Xiao Choufei Wu Kaifeng Li Guohong Gui Guolong Zhang Hua Yang | 2017 | Journal of Animal Science and Biotechnology2017，8，3： | 1 |
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